Name Address/P.O. Box Postal Code/City State Contact Person Telephone Fax Email Website Social Media Number of Employees Founded (year) Type of Laboratory Areas of Activity
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IBA Lifesciences GmbH
High performance research tools for cell and protein isolation
Rudolf-Wissell-Str. 28 37079 Göttingen Germany Dr Mike Rothe +49-551-50672-0 +49-551-50672-181 info@iba-lifesciences.com www.iba-lifesciences.com
IBA Lifesciences GmbH is a biotechnology company providing products for life science research in academia and industry. We develop high performance research tools for cell and protein isolation based on our proprietary Strep-tag® technology. Headquartered in Göttingen, Germany, we have built a network of worldwide distributors, making our products available in over 40 countries across 5 continents.
FL I
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~50 1996 S1
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l Cell Selection & Expansion
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l Protein Production & Assays Biological Patents
External Collaborations
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l Strep-Tactin®XT l Twin-Strep-tag® l Streptamer® Numerous in- and out-licensing contracts
Strep-tag® technology The Strep-tag® technology exploits on one of the strongest non-covalent interactions in nature: the interaction of biotin and streptavidin. Strep-tag® II and its tandem equivalent Twin-Strep-tag ® are peptide sequences exhibiting intrinsic affinity towards the biotin-binding pocket of two specifically engineered streptavidin variants, Strep-Tactin® and its high affinity version StrepTactin®XT. The range of selectable affinities as well as the reversibility of the binding interaction makes the Strep-tag® system a universal tool for isolation of proteins, cells, and exosomes.
Strep-tag® technology in protein purification and analysis The Strep-tag® system enables cloning, expression, detection, purification, and immobilisation of recombinant proteins. The highly specific interaction of the Strep-tag® with Strep-Tactin® ensures efficient one-step purification of the protein of interest and isolation of Strep-tagged targets even from crude cell lysate in unparalleled purity. The mild and physiological conditions promote the yield of fully functional proteins, making the system particularly suitable for purification of enzymes as well as structural investigations, protein-protein interaction studies, ligand-receptor investigations, or even separation of living cells for re-culturing processes. The Strep-tag ® technology is compatible with a large number of protein classes, e.g. metalloproteins, membrane proteins, and fragile protein complexes with multiple subunits. Simultaneously, a high tolerance towards different buffers
