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Coherent Inc

5100 Patrick Henry Drive Santa Clara, CA 95054 USA Petra Wallenta (for EU) +49-6071-968-0 (for EU) tech.sales@coherent.com www.coherent.com 1966

l Laser l Biotechnology l Laser-based solutions l DNA sequencing l Microscopy l Spectroscopy l Flow cytometry

Biosciences – The lasers you want with the performance you need.

Founded in 1966, Coherent is one of the world’s leading providers of lasers and laser-based technology for industrial, commercial, and scientific customers. With headquarters in the heart of Silicon Valley, California, and offices spanning the globe, Coherent offers a comprehensive product portfolio for applications across the life sciences and bioinstrumentation markets. These products range from simple laser diode modules to sophisticated multi-wavelength light engines. They are widely used in research, clinical, and analytical applications.

No matter whether you’re an end user or an OEM, if you need a laser-based solution in life sciences Coherent has a standard or custom product that perfectly matches your life sciences needs and your budget. Just some of the applications we support include:

Flow cytometry – Coherent supports the latest trends in multi-parameter analysers for research and clinical applications in COVID-19, as well as sorting applications such as sex selection now widely used for animal husbandry. This includes plug & play lasers at new ultraviolet wavelengths and multi-wavelength light engines that lower the cost and accelerate time to market. The superior performance of these lasers delivers data with the lowest coefficient of variation (CV).

Confocal microscopy – From the legacy 488 nm wavelength to our yellow (e.g., 561 nm) and near-IR (980 nm) wavelengths, Coherent has the perfect wavelength and power to match any dye or genetically expressed fluorescent protein. These lasers offer the ideal combination of a round, clean (M2 ≤ 1.1) beam and low output noise.

European Biotechnology

DNA sequencing – Our unique wavelength and power scalable technology gives you the ideal laser wavelength to match any fluorescent nucleotide, as well as the power range needed to support high-throughput applications.

Super-resolution microscopy – Coherent provides lasers with the adjustable power needed for both stochastic photoswitching techniques like STORM and PALM, as well as deterministic techniques like STED and RESOLFT. The high beam quality and low noise of these lasers enable images with the highest possible resolution.

Spectroscopy – The unmatched breadth of the Coherent laser portfolio means that our lasers can be found in every laser-based spectroscopy method used in the life sciences. This includes narrow-line lasers for Raman, laser-spectrometer modules for the latest THz-Raman, and pulsed lasers optimised for both Maldi-TOF and LA-ICP-MS. Plus our one-box ultrafast lasers simplify even complex techniques like CARS and SRS.

Multi-Photon Excitation (MPE) Microscopy – Coherent is a recognised leader in MPE imaging with a complete range of turnkey lasers delivering brighter images, deeper imaging, faster imaging, label-free imaging, and more. These range from widely tunable lasers to a new family of economic fixed-wavelength femtosecond lasers for both OEM and research applications, including label-free translational studies.

Coherent laser wavelengths range from the deep ultraviolet through the near-IR, with custom OEM wavelengths also available. Output powers span from milliwatts through multiple watts. And pulse widths cover everything from CW to a few femtoseconds.

For product updates, visit the company’s website at http://www.coherent.com.