Presentation-Paediatric onset multiple sclerpsis

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Ongoing clinical trials with high efficacy DMT A Study To Evaluate Safety And Efficacy Of Ocrelizumab In Comparison With Fingolimod In Children And Adolescents With RelapsingRemitting Multiple Sclerosis (Operetta 2) 2022-2025 233 participants (10-17 years)

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis 2020-2027 Non-randomized Open label Clinical Trial Estimated Enrollment : 36 participants

Annualized relapse rate (primary)

Outcome measures Serum Concentration of Ocrelizumab during treatment according to bodyweight

N of new or enlarging T2- lesions

Levels of CD19+ B-cell Count in Blood

N of T1 Gd lesions

Developmental Milestones

Outcome measures

Incidence and severity of adverse events

Adverse events


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