MS Typical MS-based hyperintensities within the periventricular region, juxtacortical region, and in the cerebellum Neuromyelitis optica spectrum disease (NMOSD) Longitudinal extensive transverse myelitis involving the brainstem and extend over the entire cervical portion of the spinal cord
MOGAD Bilateral optic neuritis, optic nerve edema, contrast enhancement Cervical spinal cord lesion spanning over 2.5 vertebral levels
ADEM Multiple, diffuse, ‘fluffy,’ poorly defined T2 hyperintense lesions involving both grey and white matter in supra- and infratentorial region ADEM acute disseminated encephalomyelitis; MOGAD myelin oligodendrocyte glycoprotein antibody spectrum disorder Jakimovski D, et al. CNS Drugs. 2022 Jan;36(1):45-59