FRMC Program

PRELIMINARY SPEAKERS

Nicolas Rivron, PhD

LimorMan,MD, MMedSci

ShermanJ. Silber,MD

ProfessorofPediatrcsand PublcHeathatBoston UnversityChobanan& AvedsanSchoo ofMedcne Editor-n-Chiefemeritus,The JAMAjournals

DemiánGlujovsky, MDMSc

SeniorScientst,LunenfedTanenbaumResearch nsttute; ScentificDirector TRO VF; Medica Director InsceptonLifebankCordBoodBank

Cinca ProfessorofMedcine andObstetricsand Gynecology Unversityof SouthernCaiforniaKeck Schoo ofMedcne Los Angeles CA USA

Shoukhrat Mitalipov Raoul Orvieto,MD

HeadoftheSanDiego dvsonoftheAtos InstitutesofScience former ProfessorattheSak Institute nLaJola CA,USA

Group Leader, Laboratory for B astoid Development, Inst tute of Molecu ar B otechnology the Austr an Academy of Sciences (IMBA)/ the Vienna B oCenter (VBC), V enna, Austria

AliH.Brivanlou, PhD

Medical D rector and ChiefSc entist The Center for Human Reproduction; Visiting Researcher The Rockefe ler Univers ty, President The Foundation for Reproduct ve Medic ne New York, N Y USA

ProfessorandHeadofInferti ty and VFUnit,Departmentof OBGYN,ShebaMedca Center, Te-AvvUniversty,Israel;CoEditor-in-Chief,Reproductive BioogyandEndocrnoogy

ProfessorandDirector, CenterforEmbryonicCel andGeneTherapy Oregon Health&ScenceUnversity, Portland,OregonUSA

RobertandHarretHelbrunn Professor,DrectorThe BrivanlouLaboratoryof SyntheticEmbryoogyBioogy RockefelerUnversityNew York,NY,USA

Eli Y. Adashi, MD, MS, MA

Rad ation Oncolog st and Researcher Human Oncology and Pathogenesis Program, Memor al S oan Ketter ng Cancer Center New York NY, Un ted States; Department of Radiat on Oncology Memorial S oan Kettering Cancer Center

foundationforreprodmed.com

Pasquale Patrizio,MD ProfessorandChef,Dvsion ReproductiveEndocrinology& nfertiity DepartmentofOBGYN andReproductveSciences, UniverstyofMiamiMilerSchool ofMedcine,Miami FL

AssistantProfessorof ResearchinOB/Gyn Center forReproductveMedcine, WelCornelMedicne New York,NY,USA

Zeev Shoham, MD

Director Reproduct ve Endocr no ogy Un t, Kap an Hosp ta , Rehovot and Professor of Obstetr cs and Gynecology

Hadassah Schoo of Medic ne of Hebrew University Jerusalem, srael

MichelleN. Meyer,PhD,JD

Former Dean of Medicine and B o ogica Sciences Professor of Med cal Science The Warren A pert Med cal School of Brown University

Providence Rhode Island USA Member of the Nat ona Academy of Med cine (former y the nst tute of Med cine) The Assoc at on of Amer can Phys cians and the Amer can Association for the Advancement of Science 2018 recip ent of the ASRM Lifet me Ach evement Award

Assoc ate Professor and Cha r Department of Bioeth cs and Dec s on Sciences in the Col ege of Hea th Sciences and Faculty Co-Director of the Behav oral Insights Team n the Steele Inst tute of Health nnovations at Ge s nger n Danvi le PA USA

info@foundationforreprodmed.com

Medica Director The nfertilty CenterofSt Louse,St.Louis, MO,USA

DrectorofClnicalARTand SenorScentist TheCenter forHumanReproduction New York,NewYork,NY,USA

S. Zev Williams, MD, PhD

WendyD HavensAssociate ProfessorofWomen’sHeathand ChiefoftheDivisionof ReproductveEndocrnoogyand nfertltyatColumbaUniversty rvingMedicalCenter NewYork, NY USA

PaoloRinaudo, MD,PhD

Professor of Obstetrics & Gyneco ogy, Reproduct ve Sciences University of Cal forn a, San Francisco (UCSF) San Francisco CA, USA.

DirectorandFounderofFerti ty Argentna BuenosAires, Argentna andScentfc DirectoratCEGYR-Eugingroup, BuenosAres Argentina

David F. Albertini, PhD

Ed tor- n-Chief Journal of Assisted Reproduct on and Genetics (JARG) Senior Visiting Scientist, The Center for Human Reproduct on Stem Cel B ology and Mo ecu ar Embryology Laboratory The Rockefe ler Un vers ty

JacobHanna, Founder AntonioPellicer

Associate Professor and Cha r Department of Bioeth cs and Dec s on Sc ences n the Col ege of Hea th Sciences and Faculty Co-D rector of the Behav oral nsights Team n the Stee e Inst tute of Health Innovations at Geis nger n Danvi e PA USA

Assoc ate Professor and Cha r Department of Bioeth cs and Dec s on Sciences in the Col ege of Hea th Sciences and Faculty Co-Director of the Behav oral Insights Team n the Steele Inst tute of Health nnovations at Ge s nger n Danvi le PA USA

Howard Bauchner,MD

Robert Casper,MD

Uri Elkayam, MD

JuanCarlosIzpisua Belmonte,PhD

Samuel F. Bakhoum, MD

Norbert Gleicher,MD

DavidH.Barad, MD,MSc

PRELIMINARY AGENDA: DAY 1

DECEMBER,1,2023

Welcometothe 2023Foundation forReproductive Medicine Conference!

8:30

Invitrogametogenesis, -producingeggsand spermfrombuccal smears:A summaryofthe2023 workshopofthe NationalAcademyof Medicine

12:00

The “Young Investigator Award”

Why PGT-A simply cannot work: Physiological, biological, technical, and mathematical reasons

TheOpening Lecture:Whatis wrongwithcurrent medicalpublishing?

Is the concept of embryo selection in IVF still sustainable?

4:00

Why are we using extended embryo culture to blastocyst for almost all IVF cycles?

LunchSymposium: Transferring chromosomal “abnormal” embryos?

foundationforreprodmed.com

Anothercritical lookatelective singleembryo transfer

The Breaking News Lecture: Penetrating the black box of implantation

Humanblastoid modelstoadvance ourunderstanding ofearly-stage embryos

Improving organ health and function by programmed rejuvenation

Can non-invasive PGT-A save PGT-A?

Whatisthe pregnancypotential ofunusedand/or discarded “abnormal”embryos afterPGT-A?

CoffeeBreak, PosterViewing& VisittheExhibition

The Daily Summary: Q&A with the day’s faculty

WelcomeReception atthehotel

CoffeeBreak, PosterViewing& VisittheExhibition info@foundationforreprodmed.com

PRELIMINARY AGENDA: DAY 2

DECEMBER,2,2023

Thefunctionof micronucleiin cancercells:Isthere relevancetothe preimplantationstageembryo?

8:30

Germline editing for genetic diseases: The 2023 state-ofthe-arts

Chromosomal analysis of extruded cells/fragments in preimplantationstage embryos

Howfolliclesand oocyteschangewith advancingfemaleage: HighlyIndvidualized EggRetrieval(HIER)as animportantstep toward“precison medicine”

Thepublic sopinion onpolygenicrisk scoring,likelythe nextbigsalesitem ofthe genetictesting industryinIVF

CoffeeBreak, PosterViewing& VisittheExhibition

Invitrogerm cellinduction fromfertileand infertile monozygotic twins

For how long can IVF cycles be safely delayed in cancer patients to pursue fertility preservation?

Lunch Symposium

SYMPOSIUM:Afterall, howeffectiveisoocyte cryopreservationin extendinga woman’sreproductive lifespan?

mtDNA transfer can be horizontal: A mechanism to restore compromised mitochondrial function in embryos?

Doespregnancy affectDNA methylationand, therefore, biologicalage? 9:00 9:30 10:00 10:30 11:00 11:30 12:00

Shining some light into the black box of implantation by using human stem cell-derived blastoids

Some tips and tricks after over 1,000 nuclear transfers in mice

The Daily Summary: Q&A with the day’s faculty

4:30 5:30 6:00

6:30

12:20 12:40 1:00 2:00 2:30 3:00 3:30

info@foundationforreprodmed.com

PRELIMINARY AGENDA: DAY 3

DECEMBER,3,2023

out of date?

Issuesarisingfor mankindfrom increasing utilizationofIVF

Unintended consequencesof industrializationand commoditizationof IVFpractice: PGT-Aasanexample

WhyIVFdoes nothavetobe asexpensive asitis

OUR FIRST SPONSORS AND EXHIBITORS

PRELIMINARY AGENDA: DAY 3

DECEMBER,3,2023

DoPCOSphenotypes reallyexistoriswhat wecurrentlydescribe asPCOSreallyan amalgamoftwo distinctgenomic entities?

8:30

“Laboratory-developed tests,” a major FDA loophole for the proliferation of useless and/or harmful “addons” to IVF

Where do we stand with social eggfreezing, now that we know that it is not very effective at older ages?

Societalissues arisingformankind fromincreasing utilizationofIVF

Coffee Break, Poster Viewing & Visit the Exhibition

Unintended consequencesof industrializationand commoditizationof IVFpractice

Can in vivo fragmentation of ovarian tissue and/or intraovarian injection of PRP really be considered “ovarian rejuvenation”?

The Daily Summary: Q&A with the day’s faculty

Closing Remarks