Chemical Hygiene Plan and Safety Manual - LP3004.4

Section IV: General Biological Safety

1.0 Outline

This section outlines all the basic safety precautions for working with biological standards and samples in the laboratory. It also outlines the protocols for handling, storage and disposition of these biological hazards. The laboratory is responsible for controlling all types of standards and samples and there is a rating system in place for monitoring and handling.

There are many types of biological hazards that Purity personnel will encounter while working in the laboratory environment. They include but are not limited to:

2 1 There are a variety of potential biological hazards present at the laboratory that personnel could be exposed to These hazards include, but are not limited to: microbiological positive control standards, human blood, human serum, human urine and OPIM

2.2 Biosafety Levels: This category is for microbiological hazards such as positive control standards. The range of BSL is 1-4 with 4 being the most hazardous.

2.2.1Strains of microorganisms not known to cause disease in healthy human adults. Normal safety procedures apply.

2.2.2 Moderate risk microorganisms that are associated with less serious human diseases. Extra precautionare necessary such as PPE and limited lab access.

2.2.3 High risk microorganisms with a true potential for infection via inhalation. PPE required such as respirators, double gloves and gowns. Work only to be conducted in an isolated laboratory.

2 2 4Easily transmitted very high risk microorganisms which cause life threatening diseases for which there is no treatment Hazmat suits required as well as chemical showers

2 3 Microbiological Hazards:

2 3 1 There are a variety of positive control standards used by the microbiology department

Each of these standards comes with a BSL (Biosafety Level) rating Depending on the degree of the rating, various precautions must be taken when using these standards