Skip to main content

Chia: Seeds for Change

Page 1

Chia Report

CHIA: SEEDS FOR CHANGE

A look at the human health potential, sustainability impact, and functional food potential of this mighty seed


An Ancient Superfood for the 21st Century The seeds of change may start small, but in the right environment, they grow mighty. That can certainly be said of the chia plant, whose minuscule seed grains nourished ancient civilizations for centuries - and has, in recent decades, experienced a revitalization as a superfood ideal for meeting the needs of modern consumers. Most of us refer to chia as a seed, though it’s technically a grain. Regardless of how consumers categorize it, the tiny black or white orbs far surpass their seed or grain counterparts when it comes to nutrition: Chia brings together protein, omega-3 fatty acids, fiber, antioxidants, and an array of minerals, all in a package no bigger than a pinhead. In fact, it’s the richest source of plant-based omega-3 fatty acids you can find in nature.

An Ancient Food with the highest Omega-3 content found in

40%

of Dietary Fiber

Nature: with unsuspected health benefits, Chia is an amazing sustainable source of essential nutrients. This unique nutritional profile has made it possible for chia to sustain advanced civilizations such as the Aztecs and the Mayans. And today, a mounting body of evidence shows that the grain has the potential to aid in addressing some of our most pressing health concerns, including heart disease, diabetes, inflammation, and neurocognitive and neurodegenerative conditions. Chia’s nutritional components have also proven integral to fetal and child development, positioning it to support the health of coming generations through pre- and postnatal nutrition. Chia, too, is a food that supports the health of the planet. Requiring few resources to thrive in its native environment, the crop supports humanity’s need for increased sustainability, reduced water usage, and fewer greenhouse gas emissions in our global food supply. It also contributes little to no waste in terms of unusable byproducts. The versatile grains can be enjoyed whole (both raw or soaked) or cold-pressed into a nutrient-dense oil, while the leftover

22%

of Proteins

20%

of Omega-3

6%

of Omega-6

Minerals

Calcium, phosphorus, magnesium, potassium

matter can be ground in a fiber- and protein-rich flour. Altogether, chia’s nutrition, sustainability, and versatility make it a highly appealing option for consumers and food manufacturers. Here’s a closer look at what the science has uncovered about this impressive little seed, and how chia can be utilized to support the health of people and our planet as a whole.

BACK TO THE COVER

Vitamins Antioxidants Gluten-free

AN ANCIENT SUPERFOOD FOR THE 21ST CENTURY

3


Chia’s History in a Nut (or Seed) Shell Chia, or Salvia Hispánica L, is a native plant of the Central

Today, chia has leapt from a little-known alternative crop

American sub-tropical region. A dietary staple of Aztec

to an industrial one, with between 60,000 and 100,000

and Mayan societies, chia was consumed as a nourishing,

tons produced annually. It has earned recognition from

high-energy grain and employed in tribal and religious

scientists and nutrition experts alike as a novel food

ceremonies. It was so valuable, in fact, that the Aztecs

offering many of the nutritional properties currently

used the crop as a form of currency.

lacking in human diets, such as omega-3 fatty acids, fiber,

Records indicate that chia sustained these advanced

protein, and a suite of potent phytochemicals.

civilizations from as early as 3,500 B.C. The crop was banned and replaced with European food crops like wheat and barley when the Spaniards invaded South America

The fact that chia is plant-based, free of

in the 1500’s. Chia production largely lay dormant for

gluten, zero net carbs, and high in protein has

several hundred years thereafter, until unexpectedly and

also made it popular among multiple dietary

enthusiastically reemerging in the late 20th century.

patterns, including vegan, low-carb/keto, and

The banned crop …. Revived!

gluten-free diets.

In the early 1990s, chia’s exceptional nutritional benefits

That’s especially true due to the fact that chia is highly

and strong food industry potential earned it a spot in the

accessible, relatively affordable, and easy for consumers

North Western Argentina Regional Project (NWARP), a joint

to use at home. At the same time, it can be incorporated

project of the University of Arizona and the Argentinean

into a wide range of functional foods to enhance their

government aimed at identifying and producing

nutrition, improve palatability and textural performance,

alternative crops at industrial scale. Chia earned the

and strengthen a brand’s position as a supporter of

heart—and trust—of a number of growers who provided

sustainability.

the project with a formal business structure to support the seed's expansion. This cooperative eventually evolved into Benexia®, the Chilean-based world’s foremost chia ingredient specialist company.

CHIA: SEEDS FOR CHANGE


BACK TO THE COVER

AN ANCIENT SUPERFOOD FOR THE 21ST CENTURY

5


The Health Benefits of Chia Tiny but tremendous Plenty of superfoods may fit this description, but none so more than chia seeds. While each individual grain is no bigger than the period at the end of this sentence, collectively, you'd be hard-pressed to find another food that packs so much goodness in a single spoonful. Chia's nutritional profile goes big on fiber, healthy fats, quality protein, and antioxidants, all of which have been shown to meet the needs of some of our most pressing health concerns.

Chia Nutrition at a Glance What exactly makes chia so special? When you take a look at the grain's nutritional high points, you'll quickly see what sets it apart. A one-ounce (2 Tbsp) serving of chia seeds contains1: 140 Calories 5 g Protein 10 g Fiber 12 g Carbohydrates 9 g Fat, including 5 g ALA omega-3 fatty acids 5 g ALA omega-3 fatty acids

The Balance is Essential Here's why omega-3s matter: balancing out the types of fat in the diet by adding omega-3s is beneficial for health. The typical Western diet includes too much saturated fat and not enough unsaturated fats (i.e., monounsaturated and polyunsaturated fats). Within the polyunsaturated fats category, there is disproportionally more omega-6 polyunsaturated fats than omega-3s given the prevalence of ingredients like corn, soybean and safflower oil.

179 mg Calcium 2 mg Iron 95 mg Magnesium 244 mg Phosphorus 0.262 mg Copper 0.771 mg Manganese 15.6 µg Selenium

OMEGA-3 FATTY ACIDS Chia seeds aren't just any source of omega-3 fatty acids. They’re the richest source of the essential omega-3 fatty acid alpha-linolenic acid (ALA) found in nature with more than 60% of their total fat being

While omega-6 fatty acids are healthy, balancing out the type of fat in the diet by adding omega-3s and limiting saturated fat is beneficial for health. A diet high in omega-3-rich foods can help bring a better balance for good health. That can help the body function optimally, and in turn support cardiovascular health, immune health, reduced inflammation, neurodevelopment, and mental health.

ALA. They’re also an accessible and affordable option for omega-3s compared to other foods.

BACK TO THE COVER

THE HEALTH BENEFITS OF CHIA

7


63%

plant omega-3

FATTY ACIDS FROM PLANT-SOURCE OILS FATTY ACIDS (% TOTAL FA) Oil Fatty Acids

Hemp

Borage

Sasha Inchi

Flaxseed

Perilla

Ahí Flower

Chia Seeds

75

56

81

73.6

75.8

78.5

82

ALA

16

0.6

48

<58

60

42

>63

GLA

4

20.4

<0.1

<0.1

<0.1

4.5

<0.1

SDA

<0.01

<0.01

<0.1

<0.1

<0.1

17

<0.1

OMEGA-6

55

35

33

15.3

14.7

15

15.4

RATIO O6/O3

2.8

1.7

0.69

0.27

0.24

0.24

0.23

PUFAS OMEGA-3

CHIA: SEEDS FOR CHANGE


FIBER Fiber is a must for satiety, sustained energy, and balanced blood sugar control. But that's only the beginning. Fiber is essential for maintaining the health and integrity of the gut microbiome, exerts a cholesterol lowering effect4, and even offers protection against some forms of cancer5,6. In short, staying healthy without roughage is rough! The problem is, only one in 20 Americans meets the daily

CHIA FLOUR (XIA POWDER-435 LM) VS. TRADITIONAL GRAIN SOURCES Analysis of total dietary fiber components 60

50

40

recommendation for fiber7. Eating more chia seeds is one of the easiest ways to bridge this gap, though. A single

30

ounce (about 2 Tbsp) delivers nearly 40% of an adult's daily fiber needs8, and offers both soluble and insoluble

20

types of fiber. To call it nature's fiber supplement wouldn't be inaccurate.

10

0

Xia Powder-435 LM

Whole Oats

Total Dietary Fiber (TDF)

Whole Wheat

Brown Rice, Long Grain

Unsoluble fiber

Soluble fiber

Sources: USDA National Nutrient Database for Standard Reference, Release 23; J Agric Food Chem, 2010, 49: 2437; Cereal Chem, 1999, 76: 788; cereal Chem, 2000,77: 673.

GLYCEMIC INDEX (GI) COMPARISON

100

Glucose

70

White Bread Whole Grain Bread

60

Oats (Hot Cereal)

58

Chia Flour: Xia Powder-435 LM (Bread)

25 0

BACK TO THE COVER

20

40

60

80

100

THE HEALTH BENEFITS OF CHIA

9


More (Plant) Protein, Please! Nearly two thirds of consumers say they're trying to consume more protein. In fact, it's the number-one nutrient people say they want more of in their diet. And sustainable sources of plant protein, like chia seeds, are more desirable than ever, with one in four adults saying they're trying to get more protein from plants compared to a year ago10.

PROTEIN

PHYTOCHEMICALS

Consisting of 20% protein, chia is a high-quality, plant-

Foods like kale and berries rack up a lot of attention for their

based source of this all-important nutrient. Protein is

high antioxidant capacity. In fact, chia seeds deserve the

central to the construction of bodily tissues, is intricately

same consideration. They're packed with phytochemicals

involved in the immunological process, and is needed

including phenolic acids, tocopherols, tocotrienols, and

to generate antibodies, enzymes, and hormones.

phytosterols, and boast a total ORAC capacity between 8,000

Unlike many other plant sources, chia seeds contain all

to 11,000—very high and varies as with all crops depending

nine essential amino acids, including high amounts of

on Mother Nature under optimal farming conditions—

glutamine, in a highly bioavailable form with no known

which is on par with blueberries and cranberries11. These

anti-nutritive factors. It's also highly digestible, with a

supernutrients are known to guard cells from free radical

PDCAAS score of 0.859.

damage and revert the cell aging process and oxidation. Altogether, that can have a protective effect against cancer, heart disease, lung disease, cognitive decline, and more12.

High Quality Plant-based Protein CAKE/FLOUR

PDCAAS

MINERALS

Soy

0.99

Chia Seeds

0.95

Chia's mineral content towers above most other ancient

Canola

0.9

grains, including quinoa, amaranth, spelt, and millet. It's

Hemp

0.84

Pea

0.78

Quinoa

0.63

Sunflower Seeds

0.54

Fax

0.48

Sesame

0.43

**Ertl, P., Knaus, W., & Zollitsch, W. (2016). An approuch to including protein queality when assesing the net contribution of livestock to human food supply. Animal, 10 (11), 1883-1889. doi:10.1017/S1751731116000902.

CHIA: SEEDS FOR CHANGE

rich in phosphorus and magnesium, and is a good source of copper, selenium, iron, manganese and calcium. Altogether, chia provides an easy, tasty way to fill up on essential micronutrients that aren't always easy to find elsewhere.


Chia and Health: What The Science Says

OMEGA-3S, PHYTOCHEMICALS, FIBER, ANTIOXIDANTS

How do chia’s impressive nutritional stats translate to human

plant-based omega-3 fatty acids. The fat in chia seeds

health benefits? The omega-3s, fiber, and phytochemicals

consists of more than 63% omega-3s, which far exceeds

in this little grain are thought to offer significant benefits in

other plant-based omega-3 sources such as hemp and

helping protect against a host of diseases.

flaxseed. Chia also boasts a highly favorable ratio of

Much of chia's anti-inflammatory, disease-fighting activity is owed to alpha-linolenic acids (ALAs), those essential

anti-inflammatory omega-3 to pro-inflammatory omega-6 fatty acids13.

ANTI-INFLAMMATORY BENEFITS FOR CHRONIC DISEASE PREVENTION

There’s also a suite of potent phytochemicals to consider.

Chia comes packaged with a wide variety of

Together, these compounds help thwart and prevent

anti-inflammatory compounds that may help reduce the risk for chronic diseases where inflammation has been

oxidative damage by activating anti-inflammatory activity and simultaneously suppressing the production of

identified as an important risk factor. Health conditions

pro-inflammatory substances15,16.

that have been shown to be associated with increased

Diets supplemented with ALA have been shown to lower

inflammation include, but may not be limited to:

• • • • • • • •

Diabetes and metabolic disorders Heart disease High cholesterol High blood pressure Memory-related disorders including dementia Obesity Arthritis and joint pain

inflammatory markers. What's more, these protective benefits can be obtained by chia seeds directly. Individuals who supplemented with 4 g of chia seeds daily for 12 weeks showed a 40% reduction in C-reactive protein, an inflammatory blood marker17. Similar reductions in C-reactive protein levels have also been demonstrated in healthy adults, suggesting that ALA and chia may exert a preventive anti-inflammatory effect18.

Skin-related conditions like psoriasis

"Chia is an excellent food because of its unique matrix of nutrients and antioxidants that benefit health and nutrition. We know today that the Western diet is deficient in dietary fiber, and we could benefit from more omega-3 ALA. Chia is an excellent source of both plus a host of other vitamins, minerals, and antioxidants. Together, these nutrients support the immune system, cardiovascular health, metabolic conditions, liver health and more." Rodrigo Valenzuela, PhD, MSc. Professor of Food and Nutrition and Chia Scientist, University of Chile

BACK TO THE COVER

THE HEALTH BENEFITS OF CHIA

11


Worth noting is the fact that consumption of ALA-

How Chia Stacks Up Just how nutrient-dense are chia seeds? Here's an ounce-by-ounce comparison to some other popular superfoods14.

1,400%

enriched sources of omega-3 fatty acids can directly and significantly increase circulating levels of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid)19, the omega-3 fatty acids that have historically received more attention for heart and brain health. In other words, consumers don't necessarily need to turn to seafood sources of omega-3s such as salmon or fish oil capsules. EPA and DHA can be effectively converted from plantbased ALA omega-3 sources such as chia.

more magnesium than broccoli

Chia's fiber, specifically its soluble fiber (also called

800%

prebiotic that serves as food for probiotic ("good")

more phosphorus than whole milk

700%

more omega-3s than salmon

500%

more protein than kidney beans

mucilage), plays a key role as well. Soluble fiber is a bacteria in the GI tract. This essential nourishment helps maintain the balance of good and bad bacteria, in turn protecting the integrity of the gut lining and supporting a healthy immune system to keep body-wide inflammation low20. A balanced microbiome also supports adequate communication between the gut and the brain to ensure proper hormone and nerve function21, which may offer further protection against disease. Chia's high fiber content, too, offers demonstrable effects against inflammatory diseases such as type 2 diabetes.

500%

more calcium than milk

300%

more selenium than flaxseed

200%

more iron than spinach

100%

more fiber than bran flakes

100%

more potassium than bananas More folate than asparagus More antioxidants than blueberries More lignans than flaxseeds CHIA: SEEDS FOR CHANGE

In a recent analysis, chia seed consumption was found to significantly reduce fasting blood sugar levels, total cholesterol, and waist circumference while increasing adiponectin. These findings lead the authors to conclude that chia has potential to improve diabetes risk factors and even serve as an adjunct treatment for type 2 diabetes22. FIRST IN FIBER 23 FIBER CONTENT (g/100g)

2 Tbsp (25g)

Chia Seeds

35 g

9g

Flaxseed

27.3 g

6.8 g

Oat Bran

15.4 g

3.8 g

Sesame Seed

11.6 g

2.9 g

Sunflower Seed

11.1 g

2.7 g

Buckwheat

10 g

2.5 g

Quinoa

7g

1.7 g

Amaranth

6.7 g

1.6 g

FOOD

U.S. Department of Agriculture, Agricultural Research Service. FoodData Central, 2019. fdc.usda.gov.


As if that wasn't enough, let's not forget chia's copious

ALA consumption, too, yields lower levels of inflammatory

antioxidant compounds. The seed's potent phytochemicals

biomarkers such as C-reactive protein, which is linked

are tied to decreases in reactive oxygen species and

to lower incidence of heart attack and stroke31,32,33.

reducing inflammatory processes that may slow or

These benefits have been demonstrated in both healthy

thwart the development of disease. Chia's isoflavones,

populations34 as well as populations at higher risk for heart

in particular, have also demonstrated anticarcinogenic

disease, including those with type 2 diabetes. 33

properties24.

NEUROPROTECTIVE BENEFITS It's fair to say that fatty acids such as omega-3 ALAs

138%

support the brain's ability to fire at maximum capacity. ALA omega-3s are a key component of the brain's cell membranes, allowing them to remain nimble and

Eating chia seeds can raise blood levels of

flexible35. This increased neuroplasticity supports optimal

ALA by this much, research shows. Chia consumption also boosts blood levels of EPA omega-3s by up to 39% . 25

neurotransmitter signaling, resulting in more effective chemical communication between the brain's neurons36. OMEGA-3, AGAIN

CARDIOVASCULAR HEALTH

The effects of this optimized brain functioning are

Fat is no longer the enemy when it comes to heart health.

consuming ALA can increase brain levels of DHA,

Higher intake of ALA omega-3 fatty acids found in chia,

which may reverse memory impairment for those with

potentially far-reaching. Animal studies suggest that

specifically, may reduce heart disease risk factors and have

Alzheimer's disease37. ALA may also exert protective

been shown to decrease the risk of heart disease death .

effects during seizures by reducing neuron loss during an

Consumption of ALAs also reduces the risk of ventricular

episodic event 38. Limited research has shown, too, that

arrhythmias by more than 25% .

treatment with ALA after traumatic spinal cord injury may

26

27

reduce cell death, in turn reducing the potential effects of OMEGA-3

central nervous system injuries39.

Heart health is multifactorial, and indeed, ALA serves

Psychiatric disorders may benefit from increased ALA

to protect the heart through a number of channels. It

consumption as well. Both attention deficit hyperactivity

supports healthy cholesterol by reducing levels of LDL

disorder and depression are associated with decreased

("bad") cholesterol and triglycerides in the blood, while

levels of omega-3 fatty acids 40. Though more research

decreasing the growth rate of artery-clogging plaque28.

is needed to understand the connection between

In fact, adults who consumed 4 g chia seeds daily for 2.5

psychiatric disorders and ALA, these findings suggest

months saw an 18% decline in LDL cholesterol and a 17%

that omega-3 supplementation could play a valuable role

decline in triglycerides29.

in mental health.

Consuming of ALA-rich foods also reduces hypertension risk by encouraging healthier blood vessel function and exerting a blood pressure-lowering effect. For instance, adults with high blood pressure who consumed 35 g of chia flour daily for 12 weeks experienced an average 10-point drop in blood pressure30.

BACK TO THE COVER

THE HEALTH BENEFITS OF CHIA

13


Chia and Low Carb or Keto: An Ideal Match

PRENATAL, PEDIATRIC, AND MATERNAL HEALTH

Low-carb and ketogenic diets have grown

in utero and in early childhood. These essential fats are

increasingly popular in recent years, and the

constituents of the phospholipids in cell membranes, and

trend shows no sign of abating: Global values of

concentrations of omega-3s in the brain and retina are

the ketogenic diet market are expected to rise to

particularly high, at 40% and 60% respectively41.

Omega-3 fatty acids have long been known to play a key role in brain and eye development and function, both

$15.6 billion by 202748. But developing low-carb baked good products that score high on taste and performance remains a challenge. One ingredient poised to solve this problem is our concentrated chia fiber, called Xia Powder 435 LM, which is both naturally high in fiber and contains quality chia protein. Containing zero net carbs, the

Concentations of Omega-3:

40% 60%

in brain

in retina

high-fiber flour boasts thickening and emulsifying properties that can improve the flavor, texture, and crumb of ketogenic baked goods, helping

Omega-3s are transferred to the fetus during pregnancy

them taste more like the traditional options

via the placenta, and through breast milk for as long as a

consumers are accustomed to. From pancakes and

mother chooses to nurse. During both stages, omega-3s

waffles, breads and buns, donuts and muffins, to

accumulate in the fetal and infant brain and retina at the

cookies and cakes, chia flour's unique composition

expense of the mother. During pregnancy and throughout

can be utilized to achieve conventional flavors

breastfeeding, mothers can consume adequate amounts

and textures - without the carbs. In short, it offers

of dietary omega-3s to ensure a steady fetal/infant supply

a way for low-carb consumers to, quite literally,

of omega-3s without depleting their own vital stores 42.

have their cake and eat it too.

Historically, much of the focus had been specifically on marine-based omega-3 sources such as DHA and EPA. Now, we know that a healthy pregnancy needn't necessarily hinge on fish or fish oil consumption alone. ALA sources of omega-3s such as chia can also support brain development during the prenatal period, and in fact, it's recommended that pregnant and breastfeeding women consume both DHA and ALA omega-3s. What's more, as a precursor to DHA 43, ALA omega-3 intake can actually drive up levels of DHA and EPA. Research shows that chia oil consumption during pregnancy and breastfeeding increases the content of ALA (76%) and EPA (57%) in erythrocyte phospholipids and the content of ALA (60%) and DHA (50%) in breast milk44.

CHIA: SEEDS FOR CHANGE


Ensuring an adequate supply of ALA and DHA omega-3s isn't just important for the developing fetus, and later, the growing infant. Crucially, omega-3s may offer protection

Culture Check

against postpartum depression. A recent trial found

As a vegan food that's high in

that women who take 5 g of omega-3s daily at the end

protein and low in carbs, chia is

of pregnancy and at the onset of breastfeeding have

poised to serve multiple food and

a greater chance of alleviating some of the symptoms

health communities popular today.

related postpartum depression45,46.

The plant-based food retail market value was $7.4 billion in 2021, compared to $6.9 billion in 2020. Growth was three times faster than total food sales in 202147.

Chia is a naturally gluten-free grain whose flour can be utilized to add fiber, protein, and structure to gluten-free breads, tortillas, pizza doughs, baked goods like muffins and cookies, and more.

With less than 1 gram of net carbohydrates per 2-tablespoon serving, chia seeds are low-carb source of fiber and protein that fits the bill for trendy keto diets.

BACK TO THE COVER

THE HEALTH BENEFITS OF CHIA

15


A Highly Sustainable Food Source Chia is, by its very nature, a highly sustainable crop. Grown in its native South America, where it evolved to thrive—it’s the right plant for the right place—and can be grown with minimal additional resources. Benexia, a fully integrated company specializing in the production, processing, and commercialization of chia and chia-based ingredients, has built on these inherent qualities to yield an eco-friendly farming production process that gives back the local environment, local communities, and the planet at large. Ultimately, chia is a food people can feel good about.

REGENERATIVE GROWING PRACTICES AND HARVESTING METHODS From planting to harvesting, Benexia practices

It's important to note that this no-till policy doesn't just

regenerative agriculture to achieve lower carbon and

support the environment. It yields a highly nutritious

water footprints. These practices are incorporated

product that food manufacturers can rely on. Chia's

by the brand's farming partners in Bolivia, Argentina,

nutrient composition (and indeed, the nutrient

and Paraguay.

composition of all plant foods) is dependent on the health

It starts with sustaining and facilitating 30 to 40 meter-wide natural barriers between chia fields. These barriers, consisting of a biodiverse network of native forest, allow chia plants to grow and thrive while supporting the wellbeing and reproduction of the local flora and fauna - from the kapok or silk-cotton tree and

of the soil in which it’s grown. Foregoing tilling allows for the harvest of chia seeds with the highest omega-3 and antioxidant capacity, while ensuring greater nutritional consistency as well as product stability and shelf life. This, in turn, translates to a higher-quality product overall with better flavor.

the Brazilian fern tree to the brown capuchin, the collared anteater, and the scarlet-headed blackbird. Once the chia seeds are planted, it's up to Mother Nature to turn on the water works: Benexia's farms rely solely on rainfall as a watering source, foregoing additional irrigation inputs and preserving the region's natural water reserves. This, of course, is made possible by the fact that chia has evolved to thrive in Benexia's hyperlocal growing regions. When you put a plant in the right climate, it doesn't need much beyond simple human stewardship to thrive.

99.95%

the level of purity of chia seeds grown, cleaned and processed by Benexia After a couple years of carefully monitored harvests, chia fields are left to rest crop-free for 1-2 years during which grasses are planted and animals can graze. Once the land

No-till practices are employed when it's time for the

has been fully replenished and the soil’s inherent nutrient

chia to be harvested. Foregoing tilling preserves organic

composition is again optimal, a new crop is planted. These

matter, allowing the soil to retain more nutrients, reduce

crop rotation practices support healthier soil, which in

CO2 emissions, limits soil erosion, and preserves insect

turn yields greater crop resilience as well as more reliable

life. It also helps the soil hold onto more moisture, creating

local economic activity.

additional humidity for future crops to flourish.

CHIA: SEEDS FOR CHANGE


CLEAN, NO-WASTE PRODUCTION METHODS Fresh from the field, Benexia's newly-harvested chia seeds are processed without the use of gas or water. Seeds are cleaned and separated using physical processes such as airflow and density-based separation methods, yielding a final seed product that's 99.95% pure.

Seeds of Potential: Present and Future Applications Chia's versatility as a whole seed, oil, and flour unlocks vast potential for healthier, more satisfying, and more sustainable eating at home. It also provides manufacturers

From there, all parts of the seeds are used to ensure that

with opportunities to offer a broad array of food products

nothing is lost - and no resources are wasted. After the

made with chia ingredients that are delicious, nutritious,

seeds are cleaned, they are pasteurized with a specialized,

and optimized to meet a range of health needs.

organically certified process that uses no solvents, chemicals, or water, while the omega-3 rich chia oil is extracted from the seeds via a single cold pressing to retain maximum nutrition capacity. The oil is cleaned and purified through a filter, that, again, requires no chemicals or solvents.

CHIA AT THE CONSUMER TABLE Chia seeds are widely available at most large grocery stores as well as online - so they're easy for shoppers to find. They're also highly affordable, especially when compared to many other sources of omega-3 fatty acids,

Once the oil is extracted from the seeds, the leftover

such as seafood. And when stored properly (in a dry, cool

fibrous matter is dried and milled to separate the fiber

place), chia seeds also boast a long shelf life.

from the protein. The powdered chia fiber and protein, now a fine flour, can be incorporated into baked goods, pizza crusts, breads, and more, as a source of zero-waste, functional nutrition.

CORPORATE RESPONSIBILITY

Most important, though, is the fact that they're simple for consumers to use in meals and snacks. They're an easy way to add protein, fiber and healthy fats to smoothies and can be soaked overnight to make satisfying breakfast puddings. Thanks to their binding ability, they're highly effective at replacing eggs or fat in baked goods. Their

Considering Benexia's commitment to the planet, it may

thickening power even aids in making fruit compotes and

come as no surprise that, since its founding in 2005, the

jams without the need for much added sugar.

company is equally dedicated to supporting the welfare of its local communities. Benexia is aligned with the United Nations’ Sustainable Development goals and is on track to

Chia seeds absorb up to 12 times their weight

complete its B Corporation certification by 2023.

in water. This allows them to add a moist

As a vertically integrated company, 50% of Benexia's

and consistent texture to any recipe

partner shareholders are chia seed farmers. This

or application.

guarantees fair pricing and technical support within the company's supply chain as well as full traceability of their ingredients.

Home cooks can utilize chia oil at home, too. This highly nutritious, unrefined oil offers benefits in its own right, including a rich phytochemical profile. It can be used raw in smoothies, or as a stand-in for olive oil in salad dressings, grain salads, and pestos. The oil's surprisingly high smoke point - 420˚F / 214˚C, which exceeds common cooking fats such as olive oil, coconut oil, and butter49 - lends itself as a healthier option for high heat cooking methods including stir-frying, sautéing, roasting, and baking.

BACK TO THE COVER

THE HEALTH BENEFITS OF CHIA

17


Chia as Functional Food Ingredients

or pulverized to make similarly potent flours. (A fiber-

Chia Oil

rich flour for baking, called Xia Powder 435 LM, or a

Cold-pressed from fresh, high quality, low-moisture

protein-rich flour for beverages, called Xia Powder 125

chia seeds, chia oil is a pure, unrefined oil made

LM.) All of these ingredients boast high functionality and

without chemical solvents or diluents. Benexia's careful

versatility, making them useful tools for functional food

processing preserves chia's liposoluble nutrients and

manufacturers to create products that meet the flavor

bioactive components, resulting in an oil with the highest

and nutrition needs of health-minded consumers while

concentration of essential omega-3 fatty acids among

delivering on palatability and stability.

plant-based cooking oils.

Chia seeds can be pressed into a highly nutritious oil

Chia in the Dietitian’s Toolkit

With 63% of chia oil’s total fat consisting of omega-3 ALAs, just one teaspoon provides twice the recommended daily ALA intake, qualifying as an “excellent source.”

Registered dietitians and health professionals play an important role in making consumers

For comparison, avocado oil and extra virgin olive oil

omega-3 literate - and highlighting the

contain less than 1% omega-3 ALAs, while canola oil

value of rich omega-3 sources such as chia.

contains around 9%.

Though public knowledge of the benefits of omega-3s continues to grow, many individuals remain unaware of how achieving a healthy omega-6:omega-3 balance can impact their health, and more importantly, how a simple food like chia can help make that happen. Benexia is committed to serving health professionals and providing them with sciencebacked information to spread this important word, by providing materials such as:

Chia oil naturally possesses more omega-3s than any other oil, with higher oxidative stability and decreased rancidity, thanks to phytochemical compounds such as polyphenols (such as caffeic acid, p-coumaric acid), tocopherols (vitamin E), and phytosterols. Independent, third-party tests show that this remains true even after several heat treatments (such as sautéing or baking), making it a highly stable cooking option that isn't prone to damage or denaturing. As mentioned previously, chia oil has a smoke

• The latest research insights • Consumer friendly cooking and shopping tips • Easy, delicious recipes • Continuing education related to chia seeds, plant-based eating, cardiovascular health, ALA omega-3s, and more

BACK TO THE COVER

CHIA AS FUNCTIONAL FOOD INGREDIENTS

19


Seed Oils: Are They Really So Bad? Seed oils are in the spotlight, and some of the attention hasn’t been flattering. Recently, health-minded social media influencers have taken to suggesting that seed oils as a whole are dietary taboos. The argument? That oils like canola, soybean, corn, and sunflower are ultra-refined, prone to denaturation at high heat, and have a high omega 6-to-omega-3 ratio, which can increase levels of inflammation in the body. 3 Since chia oil is also derived from a seed, it’s natural to wonder whether it, too, might fall into this category, or whether in fact there’s much more to the story and related to our health. The truth is that refined seed oils such as canola, soybean, corn, and sunflower may develop harmful by-products when they are reheated to high temperatures repeatedly such as in commercial fryers. However, a number of quality studies have shown that omega-6 polyunsaturated fats in general are an important component of heart health.50, 51 On the other hand, while there’s no question we are eating far higher levels of omega-6s in the diet than necessary, the omega-6s are very often found in ultra-processed foods, which we know has a number of factors that may contribute to poor health, beyond oil-based ingredients, when consumed in high amounts.52, 53

What we do know: Chia oil is unique among plant-based cooking oils because it has the highest concentration of omega-3 ALA, whereas most other cooking oils have higher percentages of monounsaturated fats and/or omega-6 polyunsaturated fats, and yet it also stays stable at cooking temperatures. And chia oil is a seed oil that contributes on many levels to balancing this story and misperception about seed oils altogether. Chia oil is cold-pressed and unrefined, and is produced entirely without solvents and diluents. This process safeguards the oil’s nutritional characteristics and stability at high temperatures - up to 420 °F, as verified by independent laboratory tests. It also means, and has been shown, that the oil retains its anti-inflammatory omega-3 fatty acids - in fact, 63% of the total fat in chia oil is omega-3s, with 3 grams of omega-3s (considered an excellent dietary source) in a single teaspoon. Despite the surrounding controversy, it’s one seed oil consumers can feel good about saying yes to.

CHIA: SEEDS FOR CHANGE


point of 420 °F (214º C), which is significantly higher than commonly utilized cooking oils such as olive, sunflower, or coconut. Utilizing chia oil in food products such as dips, salad dressings, soups, rice, sautés, sauces, smoothies, fruit and vegetable compote ‘pouches’ formulated for infants and toddlers and adult snacking, and baked goods provides a built-in opportunity to dramatically increase a product’s ALA omega-3s and overall health benefits. The mild, nutty taste works well in a variety of flavor profiles too. Simply by adding more products made with chia oil, consumers have an easy, delicious way to balance the types of fat in their diets.

The Science on Smoke Points

Chia Fiber Flour A byproduct of the chia oil production process, chia

A fat’s smoke or burning point is the

flour has high potential as an ingredient for food

temperature at which an oil or solid fat

manufacturers while diverting highly nutritious food

starts to produce visible, bluish-gray smoke

matter away from landfills. Made from pure, pulverized

and an unpleasant odor. Oils heated above

and chia seeds, Benexia’s chia flour is produced through

their smoke point undergo oxidation and

a low-temperature, micro-milling system process that

chemical breakdown, forming compounds

standardizes the ingredient without the need for additives,

that may increase health risks to humans.

processing aid ingredients, solvents, or enzymes for

At 420 °F, chia oil’s smoke point is naturally

a clean, pure ingredient. The result is a functional,

higher than many other common cooking

alternative flour that's ideal for the clean snack and

oils, making it a good fit for medium-high

baking category.

heat applications—and high enough for the majority of cooking and baking approaches.

From a nutrition perspective, chia fiber flour

FAT

SMOKE POINT

Grapeseed Oil

510 °F

268 °C

consists of 56% fiber and 25% protein and is

Avocado Oil

480 °F

250 °C

an excellent source of omega-3 fats.

Refined Soybean Oil

450 °F

234 °C

Palm Oil

433 °F

223 °C

And since it’s milled from pure white and/or black chia

Chia Oil

420 °F

214 °C

seeds, it yields a pale, golden-colored flour that won’t

Refined Sunflower Oil

408 °F

209 °C

negatively impact the appearance of baked products with

Extra Virgin Olive Oil

400 °F

207 °C

a traditional ‘whole grain’ color. These attributes make it a

Coconut Oil

381 °F

194 °C

wholesome and visually acceptable choice that can stand

Virgin Olive Oil

340 °F

175 °C

in partially or fully for wheat flour in a variety of betterfor-you baked applications including: bread, tortillas, pizza dough, cookies, muffins, brownies, cakes, waffles, pancakes, crepes, bagels, flatbreads, pie crusts, and more.

BACK TO THE COVER

CHIA AS FUNCTIONAL FOOD INGREDIENTS

21


Important to point out, too, is the fact that chia flour

In addition to delivering added nutrition, chia fiber is highly functional - it can make healthy baked goods taste better and last longer.

is naturally gluten-free. This makes it an appealing alternative to lower-nutrition ingredients often found in the gluten-free sphere, such as white rice flour, potato starch, and tapioca starch. Not only does it deliver added nutrition, it performs on key functions such as binding,

With a high viscosity, the flour can be used to replace eggs, gums and thickeners (such as xanthan gum and guar gum), and oils. Its impressive absorption rate (up to 20 its own weight) means that the flour can also be utilized

emulsifying, and raising. In fact, replacing 10% of any starch source in the bakery with chia flour provides an additional 3.2 g fiber, 1.3 g of protein, and 300 mg omega-3s without a reduction in baking functionality.

to help baked goods retain moisture, maintain shelf life, and achieve a more palatable texture and crumb. Benexia

innovation in the field of keto- and low carb-friendly baked

Protein in Chia Fiber Flour

goods such as cookies, muffins, breads, and more.

Chia Fiber contains more than

has pioneered the development of bakery applications with the use of chia fiber. Collaborating with industry baking partners, these partners have paved the way for

20% high-quality protein. Here’s how the ingredient stacks up against other

Indeed, chia fiber contains <1 g net

high-protein plant flours54.

carbs, making it a shoe-in potential in the ketogenic/low-carb baking space.

FLOUR

PDCAAS

Soy

0.99

Chia

0.85

Canola

0.91

Hemp

0.84

can also have a significant effect on texture. Chia flour

Pea

0.78

is a keto-friendly flour that can solve these problems. Its

Quinoa

0.63

thickening and emulsifying properties enhance the texture

Sunflower

0.54

and crumb of low-carb baked goods without the need for

Flax

0.48

traditional flours or added sweeteners.

Sesame

0.43

Removing key baked good ingredients such as wheat flour, sugar, or starches doesn’t just pose flavor challenges, it

CHIA: SEEDS FOR CHANGE


Chia Protein Powder Chia protein is a functional powder designed to be used for liquid beverages, such as protein drinks or shakes. What makes it unique is the fact that, unlike many other powdered proteins, chia protein is also a rich source of fiber. Like chia fiber flour, chia protein is a byproduct of the chia oil manufacturing process. Once the chia seeds have been expeller-pressed to remove the omega-3-rich oil, the remaining particles are defatted and separated by size. The larger particles are used to make chia fiber (which also contains lesser amounts of protein); the smaller particles are used to make chia protein (which also contains lesser amounts of fiber).

A multifunctional, high-protein micro-milled chia powder, Benexia's Xia Powder-125 W LM is a high-quality vegan protein that is easily dispersible, low in saturated fat, and free of solvents and additives. Unlike many plant-based protein options, chia protein is a complete protein, with a PDCAAS score of 0.95, similar to soy protein which is often considered the benchmark complete protein among plant sources. It contains all essential amino acids, including significant levels of glutamine and branched chain amino acids such as leucine, valine, and isoleucine. With high digestibility and bioavailability, chia protein powder an ideal plant-based alternative to conventional protein options such as whey and egg. As a whole food protein concentrate derived from high-quality chia seeds, it's important to note that Xia Powder comes with added nutritional benefits rarely found in other protein powders: Xia Powder-125 consists of 20% dietary fiber (in the form of soluble and insoluble fibers) and 6% omega-3 fatty acids. To top it all off, it's highly palatable: The flavor is mild and nutty while the texture is smooth and grit-free, making it an acceptable alternative to consumers who may be used to more conventional powders such as whey protein.

BACK TO THE COVER

CHIA AS FUNCTIONAL FOOD INGREDIENTS

23


The Future of Chia: Looking Ahead The consumer demand for plant-based foods and food products that are both sustainable and nutrient-dense will continue to grow in the years and decades to come. So too will public awareness on the benefits of consuming high-quality proteins, more fiber, and achieving a healthier balance of omega-3 to omega-6 fatty acids. As a growing number of shoppers seek out foods with these qualities, they’ll increasingly look to chia (and products made with it) as a go-to that’s accessible, affordable, and highly versatile.

AN UNPARALLELED NUTRIENT PROFILE

And while nutrition is key for health-minded consumers,

Environmentally-friendly, low-resource production

it’s not enough to stand on alone. Today, savvy shoppers

methods. Loads of functional applications that eschew

demand high-quality, clean-label products with a

food waste. This ancient supergrain, in short, is a food

demonstrable track record for doing good. Ultimately,

that can support a healthier future - for both people and

food products that fall into the better-for-you category

the planet. With its science-backed benefits, it’s up to

demand a robust sustainability platform to even be

manufacturers, nutrition professionals, and early adopters

considered viable.

to educate consumers about this small-but-mighty seed.

CHIA SEED FOOD INGREDIENTS: COMPARED NUTRITIONAL CONTENTS CHIA SEED Serving Size

CHIA OIL

CHIA FIBER

CHIA PROTEIN

2 Tbsp

100 g

1 tsp

100 ml

2 Tbsp

100 g

2 Tbsp

100 g

25 g

100 g

5 ml

100 ml

20 g

100 g

26 g

100 g

Calories

93.75

375

45

900

36.2

181

80.6

310

Total Fat g

7.9

31.6

5

100

1.82

9.1

3.952

15.2

Sat Fat g

0.85

3.4

0.5

10.8

0.22

1.1

0.494

1.9

Omega-3 mg

5000

19900

3000

63000

1100

5500

2392

9200

Carbohydrate g

8.575

34.3

0

0

11.36

56.8

7.41

28.5

Fiber g

8.55

34.2

0

0

11.34

56.7

7.384

28.4

Available Carbs g

0.025

0.1

0

0

0.02

0.1

0.026

0.1

0.1

0.4

0

0

0.56

2.8

1.326

5.1

0

0

0

0

0

0

0

0

Gram Weight or Volume

Sodium mg Cholesterol mg Protein g

5.625

22.5

0

0

4.94

24.7

11.232

43.2

Calcium mg

130

520

0

0

178

890

218.4

840

Iron mg

1.7

6.8

0

0

5.6

28

7.28

28

Magnesium mg

100

400

0

0

82

410

166.4

640

Phosporus mg

197.5

790

0

0

186

930

390

1,500

Potassium mg

182.5

730

0

0

166

830

312

1,200

Zinc mg

1.25

5

0

0

1.08

5.4

2.34

9

CHIA: SEEDS FOR CHANGE


Authors Wendy Bazilian Wendy Bazilian, DrPH, MA, RDN is a doctor of public health, registered dietitian and American College of Sports Medicine-Certified Exercise Physiologist. An award-winning journalist and author of several books, Dr. Bazilian is an expert nutrition strategy and communications consultant to the spa industry, to start-up and established food and commodity groups, and to the healthcare industry; and frequent nutrition and wellness keynote presenter. Wendybazilian.com @bazilians Carolina Chica Carolina Chica, RDN, is a registered dietitian nutritionist with over 20 years of experience in functional ingredients, fats and oils in human nutrition, and is a leader in research and development projects on functional food and nutritional supplements and their effects on human health. In the clinical arena, she works with non-transmissible chronic diseases, and as part of integrated interdisciplinary work teams to develop a program of intervention and nutritional and dietary education. Marygrace Taylor Marygrace Taylor is an award-winning health and wellness writer based in Philadelphia, where she lives with her husband and son. Visit her at marygracetaylor.com.

DISCLAIMER Please note that the following information is intended for business-to-business use and should not be interpreted as scientific or medical advice, diagnosis, or treatment recommendations. For labeling or advertising purposes aimed at end consumers, it is essential to take into account the specific regulatory information relevant to the country or region in question. Benexia® holds no responsibility for any damages that may arise from relying on or using the information provided in this document. Additionally, the content of this document is subject to change without prior notice.

BACK TO THE COVER

CHIA AS FUNCTIONAL FOOD INGREDIENTS

25


References 1.

U.S. Department of Agriculture (USDA). FoodData Central. (n.d.) Accessed April 14, 2023: https://fdc.nal.usda.gov/fdc-app.html#/food-details/170554/nutrients

2.

Suri, S., Passi, J. S., Goyat, J. (2016). Chia Seed (Salvia Hispanica L.) – A New Age Functional Food. International Journal of Advanced Technology in Engineering and Science, 4(3).

3.

Simopoulos, A. P. (2006). Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomedicine & Pharmacotherapy, 60(9), 502–507. https://doi.org/10.1016/j.biopha.2006.07.080

4.

Myhrstad, M. C. W., Tunsjø, H., Charnock, C., & Telle-Hansen, V. H. (2020). Dietary Fiber, Gut Microbiota, and Metabolic Regulation—Current Status in Human Randomized Trials. Nutrients, 12(3), 859. https://www.mdpi.com/2072-6643/12/3/859

5.

Arayici, M. E., Mert-Ozupek, N., Yalcin, F., Basbinar, Y., & Ellidokuz, H. (2021). Soluble and Insoluble Dietary Fiber Consumption and Colorectal Cancer Risk: A Systematic Review and Meta-Analysis. Nutrition and Cancer, 1–14. https://doi.org/10.1080/01635581.2021.2008990 https://www.tandfonline.com/doi/full/10.1080/01635581.2021.2008990

6.

Farvid, M. S., Spence, N. D., Holmes, M. D., & Barnett, J. B. (2020).Fiber consumption and breast cancer incidence: A systematic review and meta-analysis of prospective studies. Cancer. https://doi.org/10.1002/cncr.32816

7.

U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2020-2025. 9th Edition. December 2020. Available at DietaryGuidelines.gov.

8.

U.S. Department of Agriculture, Agricultural Research Service. FoodData Central. (n.d.) Accessed April 14, 2023: https://fdc.nal.usda.gov/fdc-app.html#/fooddetails/170554/nutrients

9.

PCAAS calculation by Benexia® based on: Schaafsma, G. (2000). The Protein Digestibility–Corrected Amino Acid Score. The Journal of Nutrition, 130(7), 1865S1867S. https://doi.org/10.1093/jn/130.7.1865s

10.

Krok-Schoen, J. L., Archdeacon Price, A., Luo, M., Kelly, O. J., & Taylor, C. A. (2019). Low Dietary Protein Intakes and Associated Dietary Patterns and Functional Limitations in an Aging Population: A NHANES Analysis. The Journal of Nutrition, Health & Aging, 23(4), 338–347. https://doi.org/10.1007/s12603-019-1174-1

17.

Vuksan, V., Whitham, D., Sievenpiper, J. L., Jenkins, A. L., Rogovik, A. L., Bazinet, R. P., Vidgen, E., & Hanna, A. (2007). Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial. Diabetes care, 30(11), 2804–2810. https://doi.org/10.2337/dc07-1144

18.

Lopez-Garcia, E., Schulze, M. B., Manson, J. E., Meigs, J. B., Albert, C. M., Rifai, N., Willett, W. C., & Hu, F. B. (2004). Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. The Journal of nutrition, 134(7), 1806–1811. https://doi.org/10.1093/jn/134.7.1806

19.

Valenzuela, R., Bascuñán, K., Chamorro, R., Barrera, C., Sandoval, J., Puigrredon, C., Parraguez, G., Orellana, P., Gonzalez, V., & Valenzuela, A. (2015). Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. Nutrients, 7(8), 6405–6424. https://doi.org/10.3390/nu7085289

20.

Al Bander, Z., Nitert, M. D., Mousa, A., & Naderpoor, N. (2020). The Gut Microbiota and Inflammation: An Overview. International journal of environmental research and public health, 17(20), 7618. https://doi.org/10.3390/ijerph17207618

21.

Clapp, M., Aurora, N., Herrera, L., Bhatia, M., Wilen, E., & Wakefield, S. (2017). Gut microbiota's effect on mental health: The gut-brain axis. Clinics and practice, 7(4), 987. https://doi.org/10.4081/cp.2017.987

22.

Juangco, J.R., Gacute, M.C., Fernandez, T.K.I., Fider, R.A.F., Gan, A.A.K. Fernandez, L.V.D Galicia, K.V., Gapuz, A.N.L., Fredeluces, M.M.E., Flores, B.S.C., Fuentes, A.J.M., Fullero, P.M.G., Gallera, J.F.D. (2022) IDF21-0227 Effectiveness of Chia (Salvia hispanica L.) As an Adjuvant Therapy for Type 2 Diabetes Mellitus, a Meta-Analysis [ABSTRACT]. Diabetes Research and Clinical Practice, 186, 109501. Accessed April, 14, 2023: https://www.diabetesresearchclinicalpractice.com/article/S01688227(22)00313-8/pdf

23.

U.S. Department of Agriculture (USDA). FoodData Central. (n.d.) fdc.nal.usda.gov.

24.

Cisternas, C., Farías, C., Muñoz, L., Morales, G., & Valenzuela, R. (2022). Composición química, características nutricionales y beneficios asociados al consumo de chía (Salvia hispanica L.). Revista Chilena de Nutrición, 49(5), 625–636. https://doi.org/10.4067/s0717-75182022000600625

25.

Jin, F., Nieman, D. C., Sha, W., Xie, G., Qiu, Y., & Jia, W. (2012). Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. Plant foods for human nutrition (Dordrecht, Netherlands), 67(2), 105–110. https://doi.org/10.1007/s11130-012-0286-0

26.

Naghshi, S., Aune, D., Beyene, J., Mobarak, S., Asadi, M., & Sadeghi, O. (2021). Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response metaanalysis of cohort studies. BMJ (Clinical research ed.), 375, n2213. https://doi.org/10.1136/bmj.n2213

11.

Nutrient Data Laboratory (U.S.), N. Data Laboratory (U.S.). (2010). USDA database for the oxygen radical absorbance capacity (ORAC) of selected foods. Accessed April 14, 2023: https://naldc.nal.usda.gov/catalog/43336

12.

Harvard School of Public Health. (2012, September 18). Antioxidants: Beyond the Hype. The Nutrition Source; Harvard School of Public Health. Accessed April 14, 2023: https://www.hsph.harvard.edu/nutritionsource/antioxidants/

13.

Third-party analysis by EUROFINS lab for Benexia®.

14.

Djuricic, I., & Calder, P. C. (2021). Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021. Nutrients, 13(7), 2421. https://doi.org/10.3390/nu13072421

27.

U.S. National Library of Medicine, ClinicalTrials.gov. (2006). Arrhythmia prevention with an alpha-linolenic enriched diet. Accessed April 14, 2023: https://clinicaltrials.gov/ct2/show/NCT00410020

15.

Zhao, G., Etherton, T. D., Martin, K. R., Gillies, P. J., West, S. G., & Kris-Etherton, P. M. (2007). Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. The American journal of clinical nutrition, 85(2), 385–391. https://doi.org/10.1093/ajcn/85.2.385

28.

DiNicolantonio, J. J., & O'Keefe, J. H. (2020). The Benefits of Omega-3 Fats for Stabilizing and Remodeling Atherosclerosis. Missouri medicine, 117(1), 65–69.

29.

Silva, L. A., Verneque, B. J. F., Mota, A. P. L., & Duarte, C. K. (2021). Chia seed (Salvia hispanica L.) consumption and lipid profile: a systematic review and meta-analysis. Food & function, 12(19), 8835–8849. https://doi.org/10.1039/d1fo01287h

16.

Rallidis, L. S., Paschos, G., Liakos, G. K., Velissaridou, A. H., Anastasiadis, G., & Zampelas, A. (2003). Dietary alpha-linolenic acid decreases C-reactive protein, serum amyloid A and interleukin-6 in dyslipidaemic patients. Atherosclerosis, 167(2), 237–242. https://doi.org/10.1016/s0021-9150(02)00427-6

CHIA: SEEDS FOR CHANGE


30.

31.

Toscano, L. T., da Silva, C. S., Toscano, L. T., de Almeida, A. E., Santos, A.daC., & Silva, A. S. (2014). Chia flour supplementation reduces blood pressure in hypertensive subjects. Plant foods for human nutrition (Dordrecht, Netherlands), 69(4), 392–398. https://doi.org/10.1007/s11130-014-0452-7 Vuksan, V., Jenkins, A. L., Brissette, C., Choleva, L., Jovanovski, E., Gibbs, A. L., Bazinet, R. P., Au-Yeung, F., Zurbau, A., Ho, H. V., Duvnjak, L., Sievenpiper, J. L., Josse, R. G., & Hanna, A. (2017). Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: A double-blind randomized controlled trial. Nutrition, metabolism, and cardiovascular diseases: NMCD, 27(2), 138–146. https://doi.org/10.1016/j.numecd.2016.11.124

32.

Lemos, J. R., Alencastro, M. G., Konrath, A. V., Cargnin, M., & Manfro, R. C. (2012). Flaxseed oil supplementation decreases C-reactive protein levels in chronic hemodialysis patients. Nutrition research (New York, N.Y.), 32(12), 921–927. https://doi.org/10.1016/j.nutres.2012.08.007

33.

Mirfatahi, M., Tabibi, H., Nasrollahi, A., Hedayati, M., & Taghizadeh, M. (2016). Effect of flaxseed oil on serum systemic and vascular inflammation markers and oxidative stress in hemodialysis patients: a randomized controlled trial. International urology and nephrology, 48(8), 1335–1341. https://doi.org/10.1007/s11255-016-1300-5

34.

34. Lopez-Garcia, E., Schulze, M. B., Manson, J. E., Meigs, J. B., Albert, C. M., Rifai, N., Willett, W. C., & Hu, F. B. (2004). Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. The Journal of nutrition, 134(7), 1806–1811. https://doi.org/10.1093/jn/134.7.1806

35.

Vuksan, V., Whitham, D., Sievenpiper, J. L., Jenkins, A. L., Rogovik, A. L., Bazinet, R. P., Vidgen, E., & Hanna, A. (2007). Supplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trial. Diabetes care, 30(11), 2804–2810. https://doi.org/10.2337/dc07-1144

36.

Basiouni, S., Stöckel, K., Fuhrmann, H., & Schumann, J. (2012). Polyunsaturated fatty acid supplements modulate mast cell membrane microdomain composition. Cellular immunology, 275(1-2), 42–46. https://doi.org/10.1016/j.cellimm.2012.03.004

37.

Calon, F., Lim, G. P., Morihara, T., Yang, F., Ubeda, O., Salem, N., Jr, Frautschy, S. A., & Cole, G. M. (2005). Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease. The European journal of neuroscience, 22(3), 617–626. https://doi.org/10.1111/j.1460-9568.2005.04253.x

38.

Guizy, M., David, M., Arias, C., Zhang, L., Cofán, M., Ruiz-Gutiérrez, V., Ros, E., Lillo, M. P., Martens, J. R., & Valenzuela, C. (2008). Modulation of the atrial specific Kv1.5 channel by the n-3 polyunsaturated fatty acid, alpha-linolenic acid. Journal of molecular and cellular cardiology, 44(2), 323–335. https://doi.org/10.1016/j.yjmcc.2007.11.004

39.

Lang-Lazdunski, L., Blondeau, N., Jarretou, G., Lazdunski, M., & Heurteaux, C. (2003). Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats. Journal of vascular surgery, 38(3), 564–575. https://doi.org/10.1016/s0741-5214(03)00473-7

40.

Young, G., & Conquer, J. (2005). Omega-3 fatty acids and neuropsychiatric disorders. Reproduction, nutrition, development, 45(1), 1–28. https://doi.org/10.1051/rnd:2005001

41.

Lauritzen, L., Hansen, H. S., Jørgensen, M. H., & Michaelsen, K. F. (2001). The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina. Progress in lipid research, 40(1-2), 1–94. https://doi.org/10.1016/s0163-7827(00)00017-5

BACK TO THE COVER

42.

Coletta, J. M., Bell, S. J., & Roman, A. S. (2010). Omega-3 Fatty acids and pregnancy. Reviews in obstetrics & gynecology, 3(4), 163–171.

43.

Greenberg, J. A., Bell, S. J., & Ausdal, W. V. (2008). Omega-3 Fatty Acid supplementation during pregnancy. Reviews in obstetrics & gynecology, 1(4), 162–169.

44.

Valenzuela, R., Bascuñán, K., Chamorro, R., Barrera, C., Sandoval, J., Puigrredon, C., Parraguez, G., Orellana, P., Gonzalez, V., & Valenzuela, A. (2015). Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. Nutrients, 7(8), 6405–6424. https://doi.org/10.3390/nu7085289

45.

Su, K. P., Huang, S. Y., Chiu, T. H., Huang, K. C., Huang, C. L., Chang, H. C., & Pariante, C. M. (2008). Omega-3 fatty acids for major depressive disorder during pregnancy: results from a randomized, double-blind, placebo-controlled trial. The Journal of clinical psychiatry, 69(4), 644–651. https://doi.org/10.4088/jcp.v69n0418

46.

Hsu, M. C., Tung, C. Y., & Chen, H. E. (2018). Omega-3 polyunsaturated fatty acid supplementation in prevention and treatment of maternal depression: Putative mechanism and recommendation. Journal of affective disorders, 238, 47–61. https://doi.org/10.1016/j.jad.2018.05.018

47.

Gaan, K. (April 6, 2021). Plant-based food retail sales reach $7 billion. Good Food Institute. Accessed April 14, 2023: https://gfi.org/blog/spins-data-release-2021/

48.

Plant Based Food Association. (2021). 2021 U.S. Retail Sales Data for the Plant-Based Foods Industry. Accessed April 14, 2023: https://www.plantbasedfoods.org/2021-us-retail-sales-data-for-the-plant-based-foods-industry/

49.

Barrios, R. (2023). 34 Ketogenic Diet Statistics, Facts & Trends. Health Reporter. Accessed April 14, 2023: https://healthreporter.com/ketogenic-diet-statistics/

50.

Marklund, M., Wu, J. H. Y., Imamura, F., Del Gobbo, L. C., Fretts, A., de Goede, J., Shi, P., Tintle, N., Wennberg, M., Aslibekyan, S., Chen, T. A., de Oliveira Otto, M. C., Hirakawa, Y., Eriksen, H. H., Kröger, J., Laguzzi, F., Lankinen, M., Murphy, R. A., Prem, K., Samieri, C., … Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) (2019). Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality. Circulation, 139(21), 2422–2436. https://doi.org/10.1161/CIRCULATIONAHA.118.038908

51.

Su, H., Liu, R., Chang, M., Huang, J., & Wang, X. (2017). Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials. Food & function, 8(9), 3091–3103. https://doi.org/10.1039/c7fo00433h

52.

Fritsche K. L. (2015). The science of fatty acids and inflammation. Advances in nutrition (Bethesda, Md.), 6(3), 293S–301S. https://doi.org/10.3945/an.114.006940

53.

Harris, W. S., Mozaffarian, D., Rimm, E., Kris-Etherton, P., Rudel, L. L., Appel, L. J., Engler, M. M., Engler, M. B., & Sacks, F. (2009). Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation, 119(6), 902–907. https://doi.org/10.1161/CIRCULATIONAHA.108.191627

54.

For Chia oil: Third-party analysis by EUROFINS lab for Benexia®. For vegetable oils: Bockisch, M., Editor. (1998). Chapter 2 - Composition, Structure, Physical Data, and Chemical Reactions of Fats and Oils, Their Derivatives, and Their Associates. Fats and Oils Handbook, AOCS Press, 53-120.

27


Luis Pasteur 5850, Of. 403, Vitacura, Santiago - Chile |

Tel: + (56 2) 2437 5820 | info@benexia.com |

www.benexia.com


Turn static files into dynamic content formats.

Create a flipbook
Chia: Seeds for Change by Benexia - Issuu