Downtown Louisville Downtown Louisville is the oldest part of our lovely city. Its initial development was closely tied to the Ohio River. Fort Nelson, the largest early fort, was built in 1781, near what is now known as the corner of 7th and Main streets. Today, Downtown Louisville is home to beautiful high-rise buildings, historic hotels, distilleries, and tourist destinations (such as Louisville Slugger Museum and KFC Yum! Center). Dining and nightlife are alive and well downtown.
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