20. Hart RG, Catanese L, Perera KS, et al. Embolic Stroke
strokes. Stroke. 2014;45:e164–6.
of Undetermined Source. A Systematic Review and Clinical
34. Choi JY, Cha J, Jung JM, Seo WK, Oh K, Cho KH, et al.
Update. Stroke. 2017; 48:867-872
Left ventricular wall motion abnormalities are associated
21. Wachter R, Freedman B. The role of atrial fibrillation in
with stroke recurrence. Neurology. 2017; 88:586–94.
patients with an embolic stroke of unknown source (ESUS).
35. Jugdutt BI, Sivaram CA. Prospective two-dimensional
Thromb Haemost. 2017; 117:1833-1835
echocardiographic evaluation of left ventricular thrombus
22. Glotzer TV, Ziegler PD. Cryptogenic stroke: is silent
and embolism after acute myocardial infarction. J Am Coll
atrial fibrillation the culprit? Heart Rhythm. 2015; 12:234–
Cardiol. (1989) 13:554–64.
241
36. Overell JR, Bone I, Lees KR. Interatrial septal abnorma-
23. Makimoto H, Kurt M, Gliem M, et al. High Incidence of
lities and stroke: a meta-analysis of case-control studies.
Atrial Fibrillation After Embolic Stroke of Undetermined
Neurology. (2000) 55:1172–9.
Source in Posterior Cerebral Artery Territory. J Am Heart
37. Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini
Assoc. 2017; 6:e007448.
H, Mechtouff L, et al. Patent foramen ovale closure or an-
24. Ntaios G, Papavasileiou V, Milionis H, et al. Embolic
ticoagulation vs. antiplatelets after stroke. N Engl J Med.
strokes of undetermined source in the Athens stroke regis-
(2017) 377:1011–21.
try: a descriptive analysis. Stroke. 2015; 46:176–181.
38. Smilowitz NR, Subashchandran V, Berger JS. Atrial sep-
25. Diener HC, Sacco RL, Easton JD, et al.; RE-SPECT ESUS
tal defect and the risk of ischemic stroke in the periope-
Steering Committee and Investigators. Dabigatran for pre-
rative period of noncardiac surgery. Am J Cardiol. (2019)
vention of stroke after embolic stroke of undetermined
124:1120–4.
source.N Engl J Med. 2019; 380:1906–1917
39. Ntaios G, Hart RG. Embolic stroke. Circulation. (2017)
26. Hart RG, Sharma M, Mundl H, et al.; NAVIGATE ESUS
136:2403–5.
Investigators. Rivaroxaban for stroke prevention after em-
40. Amarenco P, Cohen A, Hommel M, Moulin T, Leys D,
bolic stroke of undetermined source.N Engl J Med. 2018;
Bousser MG, et al. Atherosclerotic disease of the aortic
378:2191–2201
arch as a risk factor for recurrent ischemic stroke. N Engl J
27. Nakanishi K, Homma S. Role of echocardiography in pa-
Med. 1996; 334:1216–21.
tients with stroke. J Cardiol. 2016; 68:91–9.
41. Pagola J, Pagola C, Juega J, et al. The Role of Echo-
28. Morris JG, Duffis EJ, Fisher M. Cardiac workup of ische-
cardiography Screening at the Stroke Unit. Front. Neurol.
mic stroke: can we improve our diagnostic yield? Stroke.
2020. https://doi.org/10.3389/fneur.2020.01003
2009; 40:2893–8
42. Reisner SA, Brenner B, Haim N, Edoute Y, Markiewicz
29. Saric M, Armour AC, Arnaout MS, Chaudhry FA, Grimm
W. Echocardiography in nonbacterial thrombotic endocar-
RA, Kronzon I, et al. Guidelines for the use of echocardio-
ditis: from autopsy to clinical entity. J Am Soc Echocardio-
graphy in the evaluation of a cardiac source of embolism. J
gr. 2000; 13:876–81.
Am Soc Echocardiogr. 2016; 29:1–42.
43. Rodriguez CJ, Bartz TM, Longstreth WT, Kizer JR, Ba-
30. Leung DY, Black IW, Cranney GB, Walsh WF, Grimm RA,
rasch E, Lloyd-Jones DM, et al. Association of annular cal-
Stewart WJ, et al. Selection of patients for transesopha-
cification and aortic valve sclerosis with brain findings on
geal echocardiography after stroke and systemic embolic
magnetic resonance imaging in community dwelling older
events. Role of transthoracic echocardiography. Stroke.
adults: the cardiovascular health study. J Am Coll Cardiol.
1995; 26:1820–4.
2011; 57:2172–80.
31. Camen S, Haeusler KG, Schnabel RB. Cardiac imaging
44. Reynen K. Cardiac myxomas. N Engl J Med. 1995;
after ischemic stroke: echocardiography, CT, or MRI? Herz.
333:1610–7.
2019;44:296–303.
45. Izumo M, Akashi YJ. Role of echocardiography for
32. Pritchett AM, Jacobsen SJ, Mahoney DW, Rodeheffer
takotsubo cardiomyopathy: clinical and prognostic impli-
RJ, Bailey KR, Redfield MM. Left atrial volume as an index
cations. Cardiovasc Diagn Ther. 2018; 8:90–100.
of left atrial size: a population-based study. J Am Coll Car-
46.
diol. 2003; 41:1036–43.
non-compaction: genetic heterogeneity, diagnosis and cli-
33. Pagola J, González-Alujas T, Flores A, Muchada M, Ro-
nical course. Int J Cardiol. 2010; 140:145–53.
Captur
driguez-Luna D, Seró L, et al. Left atria strain is a surrogate marker for detection of atrial fibrillation in cryptogenic 34 - diagnosticojournal.com
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Nihoyannopoulos
P.
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