Diagnostic Clinical & Laboratories
Designing for clinical decision-making
PERKINS EASTMAN UNDERSTANDS
that today’s healthcare laboratories play a pivotal role in the clinical decision-making process, and targeted treatments require rapid, accurate diagnostics.
At the same time, competition in the marketplace, expanding test menus, emerging pathogens, new technologies and therapies, the regulatory environment, and a mobile workforce, demand that labs be nimble, efficient and a great place to work.
Our extensive experience and grasp of national trends enable us to collaborate with our clients to develop lean approaches to laboratory operations such as improving specimen flow with thoughtful equipment placement and automation, optimizing space allocation, considering logistics, and providing adaptable, sustainable infrastructure. We also plan and design research and development as well as cellular therapy laboratories. Creating innovative, functional, and attractive laboratory work environments supports our clients in staff recruitment/retention, health and safety; clinicians with accurate, cost-effective test results; and patients with the right treatment for their condition.
1.0 EXPERIENCE
Memorial Sloan-Kettering David Koch Center for Cancer Care: Rapid Response Laboratory
The new Memorial Sloan-Kettering David Koch Center for Cancer Care features a “Rapid Response Laboratory.” As part of MSKCC’s Cliical Support Program, the Rapid Response Laboratory serves as a “STAT” lab for quick turn-around clinical testing, as well as the staging and shipping of patient specimens for routine testing at the main hospital campus. The facility includes a Blood Bank Depot & Cell Product Depot for the receipt, staging and internal distribution of blood & cell product for patient infusion.
UCLA CHS Telemedicine & Telepathology Lab
UCLA TELEMEDICINE | LOS ANGELES
The Telepathology Laborator y provides state-of-the-art Immunohistochemistry (IHC) and Immunofluorescence (IF) specimen preparation and analysis.
Directly suppor ting the telemedicine component, slidescanning capabilities create digital images from clinical case specimens and place them on telepathology servers, creating an unlimited potential for diagnosis.
To maintain optimum flexibility, a system of mobile lab benches can be removed, replaced, or reconfigured to adapt to changes in use and developing technologies. Fixed elements are primarily oriented at structural walls and columns; and the suspended ceiling integrates lighting and HVAC in an asymmetrical layout that maintains uniform lighting levels while not dictating the arrangement of workspaces below.
NYU Langone: Human & Environmental Exposure Assessment Facility Lab
NYU Langone: Human & Environmental Exposure Assessment Lab
NYU LANGONE HEALTH | NEW YORK, NEW YORK
SIZE
8,500 sf (790 sm)
DESIGN SERVICES
Lab Planning, Architecture
PROJECT FEATURES
Open, customizable lab spaces
Wet lab space equipped with the latest instruments and technologies
The MSB 6 houses the Human & Environmental Exposure Assessment Facility Core lab. Research is focused on environmental and biomonitoring studies designed to determine human exposure sources, pathways, and effects of organic contaminants. MSB-6 uses Biomonitoring as an approach to assess human exposure to toxic substances or their metabolites in human body fluids or tissues.
The MSB 6 lab performs a unique function – as a “select agent lab.” A Select Agent lab is a specialty lab where botulinum neurotoxin research (MSB 6) is regulated and monitored by the CDC.
MSB-6 is part of a multi-story renovation that includes wet lab space equipped with the latest instruments and technologies. Its open, customizable lab spaces encourage research teams to share resources and data. Modern seminar and conference rooms are available for graduate and research seminars.
NYU Langone: Hematological Oncology Research Lab
NEW YORK LANGONE HEALTH MEDICAL SCIENCE BUILDING | NEW YORK, NY
NYU Langone: Hematological Oncology Research Lab
SIZE
8,500 sf (790 sm)
DESIGN SERVICES
Lab Planning, Architecture
PROJECT FEATURES
Open, customizable lab spaces
Wet lab space equipped with the latest instruments and technologies
The Division of Hematology and Medical Oncology, part of NYU Langone Health’s Department of Medicine, is a major clinical arm of Perlmutter Cancer Center, a National Cancer Institute–designated Comprehensive Cancer Center. Innovative research is aimed at preventing, diagnosing, and improving outcomes in people with cancer and blood disorders. New prevention strategies and treatments for hematologic conditions and cancer are developed within the MSB 4 lab.
MSB-4 is part of a multi-story renovation that includes wet lab space equipped with the latest instruments and technologies. Its open, customizable lab spaces encourage research teams to share resources and data. Modern seminar and conference rooms are available for graduate and research seminars.
NYU Langone Medical Center: Clinical Core Laboratories
NYU LANGONE MEDICAL CENTER | NEW YORK, NEW YORK
NYU Langone Medical Center: Clinical
The Clinical Core Laboratories project on the 3rd floor of Tisch Hospital consists of Chemistry, Hematology, CPA, LIS, POCT, Microbiology, Bacteriology, Admin areas, Specialty Microbiology (Serology-Immunology, TB lab, Parasitology, Mycology, and Virology), staff lockers, public toilets, staff lounge, IT closets, conference spaces, corridors, and acid waste plumbing, as well as Dermatopathology relocation and Pharmacy expansion. The spaces under design is approximately 30,000 square feet and the projected construction schedule is 5 years with 5 phases.
New York Presbyterian- Columbia University Medical Center: Transfusion Medicine
& Cell Therapy Unit
Perkins Eastman was commissioned to renovate an existing space of approximately 4,350 sf of space within the 4th floor of the Harkness Pavilion to update the Transfusion Medicine Department, including a new Apheresis center, new Cell Therapy laboratory space designed to current Good Manufacturing Practice (cGMP) Standards, Blood Bank renovations, as well as office and support space.
The efficiently organized 1,250 sf Apheresis center consists of 4 patient bays, including one with a door for added privacy, a blood draw station, physician and nursing work areas, soiled utility, clean supply rooms, one office, reception, and patient waiting area. Thoughtfully considered finishes provide for patient comfort and staff conveniences.
New York PresbyterianWeill Cornell: Radiation/ Oncology Expansion
WEILL CORNELL MEDICINE | NEW YORK, NEW YORK
This practice is a part of one the most comprehensive care facilities in the world - the renowned NewYork Presbyterian - Weill Cornell Medical Center. Phase 2 of a multiphase relocation plan to relocate research groups from three separate departments in order to consolidate and improve efficiency with an open lab concept.
The program includes two open labs, tissue culture room, microscope room, a coldroom, an irradiator, a procedure room, and staff offices. The Xstrahl irradiator required site specific preparation to facilitate the installation in the new lab. The procedure room is where samples are examined to determine the effects of radiation on living tissue.Their research focuses on cancer treatment using a combination of chemotherapy and radiotherapy to enhance immunotherapy, and localization of radiotherapy treatments to minimize radiation exposure to surrounding organs.
Weill Cornell Medical Center: Genomics Core Laboratories
NEW YORK-PRESBYTERIAN HOSPITAL/ WEILL CORNELL MEDICAL CENTER | NEW YORK, NEW YORK
The Weill Cornell Medicine (WCM) Core Laboratories Center (CLC) was established in 2015. The CLC includes core facilities that offer resources and services in genomica, proteomics and metabolomics, flow cytometry, imaging (e.g., optical and electron microscopy, high content screening, MRI, PET/CT, and ultrasound), synthetic and analytical chemistry, and nucelar magnetic resonance (NMR).
The Genomics Core Facility of the WCM CLC provides state-of-the-art instruments and services, and expertise in their applications, to the WCM communicty and to outside investigators. Resources and services include next generation sequencing, single cell genomics, nucleic acid mass spectrometry, and real-time PCR. The facility provides consultation on project design and data analysis, and offers seminars, educational workshops and training.
New York Blood Center: Blood Processing Center
For more than 40 years, New York Blood Center has provided the community with cuttingedge research, technological and medical care innovation, and education in the field of transfusion medicine.
New York Blood Center (NYBC) identified the need to expand their blood processing capabilities with a new state-of-the-art Blood Processing and Research Facility. They chose an undistinguished beer warehouse in Long Island City to convert into a 75,000 square foot, state-of-the-art blood processing facility and research lab. NYBC needed a facility that would support a variety of highly complex functions—including blood production, research and support labs, conference and education programs, and product storage and logistics—and they wanted the building to clearly announce the Blood Center’s presence as a vital resource in the region.
Dermpath Diagnostics
DERMPATH DIAGNOSTICS | PITTSBURGH, PENNSYLVANIA
Dermpath Diagnostics
DERMPATH DIAGNOSTICS | PITTSBURGH, PENNSYLVANIA
Dermpath Diagnostics, a part of the Quest Diagnostic netwrok, is focused on providing diagnostic services to dermatologists and other physicians dedicated to the treatment of skin disorders.
Our approach for this renovation was collaborative and informative - taking into account Dermpath's national operations, protocols and standards, staff, customer experience - and developing appropriate solutions tht advance and support its mission to provide the best possible care through accurate, clear, and prompt diagnoses.
Carolinas Health Care System: Core & Acute Care Laboratory
CAROLINAS HEALTHCARE SYSTEM | CHARLOTTE, NORTH CAROLINA
A 28,800 sf interior renovation of vacated space for the CHS new core laboratory. This renovation project consolidated core laboratory testing functions from five regional hospitals and a number of medical practices into this off-site location, creating space within the main campus for 18,000 sf of Acute Lab renovations. This project used an IPD contract and LEAN 3P design process to develop the architectural design. The LEAN operational planning process was guided by understanding, modeling and simulating specimen, staff and material flow to optimize the layout and available space. As part of this project Perkins Eastman developed detailed VSK and work flow models for different specimen plans and test results.
Hospital For Special Surgery: Research Institute
HOSPITAL FOR SPECIAL SURGERY | NEW YORK, NEW YORK
Four of the five research laboratory floors were designed generically to the same layout, replicating open laboratory space with natural light, quick disconnect table-based laboratory benches, support rooms, equipment areas, and dry laboratory, office, and administrative functions. The office environment is a blend of glass-front private offices, open workspace, touchdown zones, and collaboration and amenity areas. Special care was taken to enhance the connectivity between the office and laboratory zones.
One floor is dedicated to shared core facilities which include the vivarium, environmental storage rooms, flow cytometry, chemical storage, and various other core specialty laboratories. All mechanical, electrical, and plumbing/fire protection systems are fully modernized, energy efficient, and adaptable to future changes.
NYC OCME: DNA Forensic Biology Laboratory Building
DORMITORY AUTHORITY OF THE STATE OF NEW YORK | NEW YORK, NEW YORK
The state-of-the-art DNA facility houses numerous forensic laboratories of various complexities, such as: a casework analysis lab to identify perpetrators; an exemplar lab to process both people known to be at the crime scene and paternity samples; a high-sensitivity lab for proper ty crimes; an in-situ lab for ascer taining if genetic defects causing death have been transmitted within a family, and a mitochondrial lab for body identification and missing persons cases.
The facility also houses a scanning electron microscope, biochemistry and immunohistochemistry labs, quality control/quality assurance labs, training labs, and research and development labs, in addition to support space comprising of fice, archive storage, evidence holding areas, conference center, and subterranean parking.
University of Pittsburgh Medical Center: Clinical Laboratory Building
UNIVERSITY OF PITTSBURGH MEDICAL CENTER HEALTH SYSTEM | PITTSBURGH, PENNSYLVANIA
University of Pittsburgh Medical Center: Clinical Laboratory Building
Perkins Eastman worked closely with the University of Pittsburgh Medical Center (UPMC) to consolidate and relocate central clinical laboratories to a vacant nine-story research building on their Pittsburgh campus. The 133,000 sf building houses automated testing along with related testing and diagnostic laboratories including: molecular diagnostics, virology/serology, microbiology, histology, special chemistry and molecular anatomic pathology. To effectively link the new clinical laboratories to the main hospital campus and Magee-Womens Hospital, the project includes the extension and modernization of the hospital’s pneumatic tube system.
Icahn School of Medicine at Mount Sinai Cancer Treatment Center
MOUNT SINAI MEDICAL CENTER | NEW YORK, NEW YORK
Perkins Eastman programmed and designed the new Derald H. Ruttenberg Treatment Center of the Tisch Cancer Institute. Spanning the third and fourth floors of the Hess Center for Science and Medicine and the adjacent Residential Tower, this spacious $16.2 million cancer treatment facility provides a contemporary care environment for patients.
The third floor houses 48 exam/consult rooms, each of which can comfortably accommodate family or friends for patient support. Clinical trial enrollment is encouraged here to further cancer research. Three separate infusion suites located on the fourth floor have more than tripled Mount Sinai’s capacity from 16 stations to 54. A United States Pharmacopoeia, a (USP) 797-compliant pharmacy centrally placed on this floor, facilitates chemotherapy preparation and distribution.
Morgan Stanley Children’s Hospital
NEW YORK-PRESBYTERIAN HOSPITAL | NEW YORK, NEW YORK
Morgan Stanley Children’s Hospital
Morgan Stanley Children's Hospital T9 Pharmacy was designed with space to acommodate a Robotic IntraVenous Automation (RIVA) in the near future. The robot will aid in the pharmaceutical process for this full-service pharmacy.
Servicing the hospital in which it is located, the pharmacy features a clean room, USP 797 standards, a high-risk room, an anteroom, a prep room, and a staging room.
As a 24/7 pharmacy, it is essential that this facility stay fully operational and efficient at all times. The hospital is updating the existing facility because it was not up to the contemporary best practices. Additionally, the hospital set a goal to increase production capacity and update to meet USP 797 requirements.
Danbury Hospital Biomedical Research Institute
DANBURY HOSPITAL | DANBURY, CONNECTICUT
Danbury Hospital
Perkins Eastman developed a new 17,000 sf (1,579 sm) Research and Development Laboratory focusing on Cancer, Cardiology, Obstetrics, and Gynecology Research for the Randy Ruggles Biomedical Research Institute at Danbury Hospital. The new facility houses state-of-the-art open laboratories, as well as dedicated Cell Culture, Tissue Culture and a Molecular Biology laboratory and DNA and RNA lab rooms.
This facility has two state-of-the-art conference rooms for teaching, video conferencing and full administrative and support offices. The facility also has a Lyme Disease Research Facility for their continued research on the disease.
New York City Department of Health Public Health Laboratory Building Study
NEW YORK CITY ECONOMIC DEVELOPMENT CORPORATION AND THE NEW YORK CITY DEPARTMENT OF HEALTH & MENTAL HYGIENE | NEW YORK, NEW YORK
New York City Department of Health Public Health Laboratory Building Study
Perkins Eastman conducted the Space Needs Analysis and created the Conceptual Design for the proposed relocation of the NYC Department of Health & Mental Hygiene Public Health Laboratory (PHL) from its existing location at 455 First Avenue to a site on NYC Health + Hospitals’ Harlem Hospital campus at 137th Street and Malcolm X Boulevard. The over-arching goals of this analysis were to provide an updated assessment of the new facilities’ functional program requirements, and a Conceptual Design for the new facility which will become the basis of design for the new PHL building.
John Wayne Cancer Institute
PROVIDENCE ST. JOHN’S HEALTH CENTER | SANTA MONICA, CALIFORNIA
John Wayne Cancer Institute
PROVIDENCE ST. JOHN’S HEALTH CENTER | SANTA MONICA
The JWCI will be relocated to a new building enabling the Cancer Institute to:
• Update and replace aging and poorly configured facilities with modern, flexible, and energy efficient medical research labs
• Enable continuous interaction between cancer clinics and infusion to enhance translational programs and collaboration between providers and researchers
• Accommodate non-cancer research to support Cardiology, Neuroscience and Musculoskeletal investigators
• Centralize clinical trials administration to support the entire medical center; and
• Expand and improve the Biorepository to store more specimens.
Kuwait University Health Sciences Center: Hospital Clinical Lab Facility
KUWAIT UNIVERSITY | KUWAIT CITY, KUWAIT
Kuwait University Health Sciences Center: Hospital Clinical Lab Facility
KUWAIT UNIVERSITY | JABRIYA, KUWAIT
The KU clinical lab planning aims to create a future-ready laboratory that incorporates the latest technology and principles of infection control and safety. The design emphasizes flexibility to adapt to anticipated changes, including pandemics, while maximizing efficiency in specimen workflow, staffing, and space utilization to enhance patient care. The design will follow best practices for open lab layouts, featuring ceiling-mounted plug-and-play utilities to facilitate adaptability. Enclosed rooms with anterooms will be included where special infection control or hazardous material containment is necessary.
To balance automation with manual processes, the lab will incorporate redundant equipment and space, ensuring fast turnaround times and reliable testing. For instance, both manual extraction and automated systems will be available in Pre-PCR, and Cytology Read will feature both traditional microscopy and digital systems with AI.
About Perkins Eastman
Architecture is a powerful platform for encouraging curiosity and discovery through that we craft environments that engage, empower, and delight.
Founded in New York City, Perkins Eastman is a global planning and design firm that has grown to include more than 1,100 employees working out of a combined 24 interdisciplinary offices around the world. Our talented team of dreamers, thinkers, and doers promote a diverse design dialogue resulting in more thoughtful “Human by Design” solutions to meet the challenges and complexities of today’s world.
Our portfolio comprises work in a wide range of specialized project types. But at the core of our philosophy is looking beyond any single practice area or building type to find design opportunities through the convergence of our diversity of practices, disciplines, and perspectives to yield practical and holistic solutions. We promote a culture of collaboration, mentoring, and crosspollination of ideas and perspectives supporting the idea that design must have a direct and positive impact on people’s lives. As such, our team draws from across our convergent team to bring specific expertise for Quest.
Design Leaders for Clniical, Research and Medical Facilities
Based on our work with some of the foremost academic medical centers in North America, Southeast Asia and the Middle East, we understand that campuses are ecosystems that meet the needs of varied clinical and research users. Our approach ensures an alignment of continuously shifting practice of healthcare, science, research and education.
Our experience has covered how research spaces can foster innovation and how technology-rich spaces might transform scientific discovery, to working with our on-staff environmental and
behavioral psychologists can understand how to bridge the socio-economic barriers that impede effective interprofessional health education. Our significant experience on the clinical and translational research side of academic medical centers means we know how precious time and access is for clinician–researchers.
Complex Renovation Expertise
Complex renovations offer the potential to create dynamic, cost-effective spaces which would be impossible to replicate if the original building had not existed. Perkins Eastman has extensive experience programming and designing complex renovations for clinical and research use. This ranges from turning a former warehouse into the Mt. Sinai Institute for Advanced Medicine, a comprehensive, patient-centered organization designed to provide care and treatment for all patients living with HIV and AIDS, converting a former dairy barn into a design school for a State University of New York campus; to gut renovating and expanding a physics research building at the University of Chicago while not disturbing an ongoing 40-year dark-matter particle experiment in the basement.
In Pursuit of High Performance
As one of the world’s largest design firms, Perkins Eastman has a significant obligation and opportunity to have a positive impact on the built environment. Aligned with our renovation experience, fewer things are more sustainable that giving an old building new purpose. As designers of America’s two highest scoring LEED facilities, we strongly believe that Quest can achieve highperformance energy use — and that it can be done without a cost premium. It just requires the right strategies at the start.