Pharmaceutical & Cosmetic Review March 2020

Page 34

FRAGRANCES

How to keep a fragrance fabulous forever

Oxynex ST may just be a formulators dream come true. Not only are the essential elements in any cosmetic formulation protected, such as the fragrance, vitamins, active ingredients and UV filters, but there are also a whole host of well-supported skin care claims that can be made. Karen Maier, head of performance materials at Merck South Africa, explains. substances and is

DID YOU KNOW?

Superior stabilisation

stee Lauder once said, ‘perfume

Chemical deterioration Oxynex ST liquid not is an auto-oxidative process caused by action protecting fragrances only offers protection of oxygen in air and can from unwanted for fragrances, but also lead to rancidity. Adding antioxidants to your changes in colour stabilises dyes, vitamins formulations will inhibit the or smell. auto-oxidation process, and UV filters – at a helping to stabilise The DESM in Oxynex relatively low concentration. and protect your formulations. ST is a unique molecule, For fragrances, the

is like a new dress. It makes

which, with its specific

you quite simply marvellous’.

structure, ensures light stability.

However, a creased new dress,

DESM has a sterically stabilised phenolic

particularly capable of

E

recommended addition rate is 0.5 percent whereas it can be as low as 0.1 one for dyes.

or perfume that has gone stale, could

function as well as the benzylidene

destroy the feeling of marvelousness in

malonate function. Together these two

able to show that Oxynex ST liquid has

an instant.

functions support the stabilisation of light

superior stabilisation compared to

sensitive ingredients.

traditional photo-stabilisers. For example,

Formulators often face serious challenges when formulating with light-

The phenolic function provides the

In various studies, Merck has been

the photo-induced degradation of

sensitive ingredients and fragrance

antioxidant functionality, the benzylidene

is among the most challenging.

malonate function is a photo-stabiliser

Fortunately, there is a solution –

and a triplet energy quencher and the

solution of 0.1 percent Vanillin and

Diethylhexyl syringylidene malonate

carbon chain residues of the molecule

approximately 0.5 percent DESM was

(DESM), the active ingredient in Oxynex

ensure hydrophobicity, making this a

measured at λmax 281nm.

ST liquid. DESM provides highly effective

processible liquid which is miscible

stabilisation of light-sensitive cosmetic

with oil.

34

| MARCH 2020 | P C Review

Vanillin was investigated photometrically. The light absorption of an ethanolic

Data clearly demonstrates a significant improvement in the photostability of


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