MED Magazine January February 2019

Page 1

Eye Bank Leads the Way in QA USD Healthcare Students Expand Their World View

JANUARY FEBRUARY

A Conversation with LifeScape’s New CEO

VOL. 10 NO. 1

2019

SANFORD’S FIRST LORRAINE CROSS AWARD DR. KATHERINE HIGH AND DR. JEAN BENNETT THE SOUTH DAKOTA REGION’S PREMIER PUBLICATION FOR HEALTHCARE PROFESSIONALS



ORTHOPEDIC AND SPECIALTY HOSPITAL OPENING JAN. 7, 2019

Regional Health Orthopedic & Specialty Hospital combines top physicians, advanced treatment and the latest technology to deliver high-quality care to our patients. Whether patients experience pain, have an injury or seek to enhance their competitive edge, our team of specialists can help them accomplish their goals and get back to doing the things they love.

SERVICES:

N

16

Catron Blvd.

Neurosurgery

Orthopedics

Pain Management

Physical Medicine and Rehabilitation

Plastic Surgery

Podiatry

Regenerative Medicine

Sports Medicine

Therapy Services

Weight Management

Wound Care

Regional Way

Cargiver Circle

1635 CAREGIVER CIRCLE, RAPID CITY, SD 57702 (Corner of Catron Blvd. and Hwy 16)

orthopedicspecialtyhospital.regionalhealth.org 160881_1218


VO LU M E 1 0, N O. 1 ■ JA N UA RY / F E B R UA RY 2019

Inside This Issue

CONTENTS PAGE 6 | THIS MONTH ONLINE A roundup of exclusive content and other features available only on the website.

FROM US TO YOU

W W

ELCOME to the 10th Year of MED Magazine! If you’re new here,

we’d like to introduce ourselves.

PAGE 8 | [INTERVIEW] LifeScape's New CEO on Meaning, Expansion, and 'Drinking from a Fire Hydrant'

MED Magazine is the premiere

PAGE 10 | NEWS & NOTES Ribbon cuttings, new technology, promotions, and more

Dakota region. And if you’re a

ON THE COVER

PAGE 14 | Leading the Way in QA: Dakota Lions Sight and Health

lifeblood of our business.

SANFORD’S FIRST LORRAINE CROSS WINNERS

Sioux Falls’ eye bank is setting the standard for quality assurance among eye bank professionals across the country

■ By Alex Strauss

The inaugural $1 million scientific prize is a win for two researchers, for gene therapy, and for Sanford. PAGE

PAGE 19 | [RESEARCH] Sioux Falls Researcher Wins Area’s First Lush Prize Animal-free cancer research model attracts international attention PAGE 20 | Overseas Research Expands World View for USD Student Scientists PAGE 23 | Upcoming Events Conferences, Symposiums and Spring events

publication for and about the business of medicine in the South long-time MED Magazine reader, thank you! Readers like you are the This year, we’re bringing you more of what you asked for–interviews with the area’s most fascinating people, an expanded News & Notes section to keep you up to date, and a roundup of winter and spring events and CME opportunities. Do you have news to report, an event to announce, or an opinion to share? No one gives you more ways to do it than MED. Send it our way any time at Info@MidwestMedicalEdition.com. Here’s to a healthy, happy, and productive new year!

16

—Alex & Steff

ON THE COVER / Front row (l to r): David Shulkin, Katherine High, Jean Bennett, Andy North Back row: (l to r): Kirk Penney, Micah Aberson, Kelby Krabbenhoft, Miles Beacom, Cindy Rarick. Photo by Lawrence and Schiller.

CONTACT INFORMATION STEFFANIE LISTON-HOLTROP

ISSUE

VP Sales & Marketing Publisher / MED MAGAZINE, LLC Sioux Falls, South Dakota

JAN/FEB

605-366-1479

MARCH

Steff@MidwestMedicalEdition.com

APRIL/MAY

Vice president Sales & Marketing STEFFANIE LISTON-HOLTROP

ALEX STRAUSS

JUNE

Editor in Chief

JULY/AUG

June 10

Editor in Chief / ALEX STRAUSS

605-759-3295

SEP/OCT

July 10

Graphic Design / CORBO DESIGN

Alex@MidwestMedicalEdition.com

NOVEMBER

Oct 10

Photographer / JULIE PRAIRIE PHOTOGRAPHY

WEBSITE

DECEMBER

Nov 10

MidwestMedicalEdition.com

NEXT ISSUE

MAILING ADDRESS

Editorial contributions due Feb 1

PO Box 90646, Sioux Falls, SD 57109

Ads due Feb 10

Web Design / LOCABLE Digital Media Director / ALYSSA MCGINNIS

4

2019 ADVERTISING DEADLINES DUE Dec 10 Feb 10 March 10 May 10


There’s more to MED than meets the eye. What started out as a print publication is now so much more. • MED Magazine, print edition • MED Magazine, digital edition • MidwestMedicalEdition.com • MED eNews Distribution We’re reaching more healthcare professionals in more ways than ever before. Want to be part of the conversation? MED VIPs get free access to every digital issue, bi-weekly news updates, reminders of upcoming events, and more!

Sign up at the top of the Home page at MidwestMedicalEdition.com


THIS MONTH ONLINE Highlighting content and opportunities available exclusively at MidwestMedicalEdition.com

How to Post to MED’s Online Calendar for FREE

>

From the home page, locate the title “Upcoming Events Near You” at the top of the right hand side

>

Just below the visible events, click on “+ Add Your Event”

>

Input the event title, subtitle, and description. An image is optional.

>

Enter the start date of your event

>

Use the dropdown menus to select the hour and minute for the beginning and end

>

Search for your business by entering the first few letters or click the blue “Add a New Venue” button to add your business to the business directory

>

Add a website, phone number, price, category and related tags and click “Create Event” You event will appear on MED’s homepage within 15 minutes. Once you have created a free listing in the MED business directory, it will be even faster to submit your next event.

Regional Recognized for Maternity Care Tips for Presenting Like

JUNE

MED’s interactive online calendar is the ideal place to announce events— from open houses and social events to job fairs, symposiums, conferences, and more. Best of all, it is completely free and takes just two minutes. Curious? Here’s exactly how to do it:

SD’s New Rules for Handling a Data Breach

a Pro

VOL. 9 NO. 4

2018

PRAIRIE LAKES HEALTHCARE SYS TEM Portrait of a Top 20 Rural Hospital

Stories Heal By Storycast [MED Digital Partner] From the local experts in storytelling, an article on the importance of storytelling for patients, doctors and administrators wrestling with the messy complexities of disease and treatment, as well

ARE YOU ON

THE VIP LIST? E! FRE IT’SEDICALEDI TION.COM MIDWESTM

THE SOUTH DAKOTA REGION ’S PREMIER PUBLICA TION

Exclusive articles:

FOR HEALTH CARE

PROFESSIONALS

Reading MED on Your Digital Device Are you a busy professional who enjoys the convenience of reading MED Magazine on the go on your phone or tablet? Make sure your name is on the VIP list! Only MED VIPs get free access to the digital edition of MED Magazine. In addition to the convenience, you’ll be “in the know” before your peers since the digital issue is often released up to two weeks before the print issue arrives in the mail. Just enter your email address at the top of the homepage or at MidwestMedicalEdition.com/ pages/join-the-vip-list

as life and death.

Public Health 3.0: A New Opportunity to Address Health in Rural America By Sandra Melstad Public Health expert Sandra Melstad of SLM Consulting explains the concept of Public Health 3.0, a renewed, expanded approach that relies on cross-sector collaboration, consideration of collective impact, and improving the social determinants of health.

Safe Driving in Winter Weather By Gbenga Ogungbe Think you know everything there is to know about winter weather driving? Certified Safety Professional Gbenga Ogungbe, an ergonomic and loss control specialist with RAS, offers some surprising statistics and potentially life-saving advice.

Have you taken the Reader Survey?

HE T E K Y !! TA SURVE W NE DER REA 6

MED runs periodic surveys to make sure we are delivering exactly what readers like you want and need from our publications. Click on the bright yellow “New!! Take the Reader Survey” box on the right hand side of the home page. (Scroll down if you are using a digital device) The survey include just 8 “yes or no”, questions, one multiple choice, and three places to share your opinion. It is designed to take no more than five minutes. Let us know how we’re doing.

MidwestMedicalEdition.com


Digital Partners

Meet Travis Remme, Owner of Visiting Angels Living Assistance Services in Sioux Falls MED: What drew you into home care? TR: When I left my corporate job after 12 years, I had some time to think about what I wanted to do next. My wife’s aunt had end stage cancer at the time, so I spent some time visiting with her. Her family was taking her to all her appointments and helping her and it was hard since it was planting time. When I found out about Visiting Angels, I thought, ‘Wow, this company is doing essentially exactly what I was doing’ and it came full circle. I could see there was a need for this.

MED: What kinds of services does Visiting Angels provide? TR: Think of us as an alternative to assisted living or a nursing home. We commonly provide all the activities of daily living to stay safely in the home, from personal care and hygiene to meal preparation, errands, and just companionship.

MED: What about patients who need physical therapy? TR: We are not physical therapists, but we do understand that successful rehabilitation means doing the exercises at home. We know that people rehab better at home. But everyone needs motivation to work out. Having our people right there to remind and encourage them can really help a patient keep up with their PT and make faster progress.

MED: Who is a good candidate for home care? TR: Anyone who is likely to be unsafe at home. If they have frequent falling, dementia, Parkinson’s or they have had an injury and still need help when they come home from rehab. And anyone who just wants to stay at home. Many people just do not want to leave their homes and will fight tooth and nail to stay there. We can help make that possible.

See the website for more of our conversation with Travis Remme, including how to refer a patient for home care and how to broach the subject.

? The Question

“ What are you most looking forward to in healthcare in 2019?”

It could be a new piece of equipment, a new partner, an expansion, or something broader like a breakthrough in your field or an expected new medication. Send your short answer to Alex@MidwestMedicalEdition.com. We'll feature your answers online and in an upcoming issue.

January / February 2019

7


[ INTERVIEW ]

Steve Watkins LifeScape’s New CEO on Meaning, Expansion, and ‘Drinking from a Fire Hydrant’ In September, Steve Watkins, former CEO of Orion Foods, became the new CEO of Sioux Falls-based LifeScape. Since his unanimous approval by the Governing Board, Watkins has jumped into his new role with both feet — an experience he describes as “trying to drink from a fire hydrant.” MED caught up with him to find out how he is settling in and what is next for LifeScape, an independent, non-profit organization serving special needs adults and children across the region. MED: LifeScape is a pretty big change from food manufacturing. What drew you to this position?

SW:

The biggest thing is that I knew that I wanted to migrate

out of for-profit into something that really mattered, something tangible, something that involved giving back to my community. At Orion, we supported organizations including Children’s Home Society and Sanford’s Children’s Hospice, which was very meaningful to me. When I was contacted about LifeScape, I wasn’t even actively looking, but it really felt like the right move. MED: In the board’s recommendation of you, they said they thought you could help LifeScape “address the big challenges”. What are these challenges?

SW:

There are several. The biggest one is workforce. In some

cases, we have had to turn away individuals looking for our services because we did not have the staffing to meet their needs. This is an economic but also a cultural issue and it means that we may need to look more closely at things like retention and even automation. The other big challenge for us is space. What we are seeing is that there are demands for services that exceed our capacities. A lot of that has to do with space. MED: So that begs the question . . . how are you going to deal with that?

SW:

Anne believed that it was time to expand to a new facility,

a new campus, and I am excited to take on that challenge. Our Foundation gave us $6 million to buy 40 acres so we are in the

8

MidwestMedicalEdition.com


process of determining what the landscape looks like for property. We are

Honey Balsamic-Glazed Ham

looking at an overall project of about $60 million for a campus that would bring together most of the high level services that we currently provide in 18 buildings across Sioux Falls. We are putting together the appropriate committees and hope to have a more formal timeline in place by March. MED: Today, as we are talking, you are just a month into your new position. What have you learned so far?

SW:

The biggest take-away in my first

month is that the level of excellence in care that LifeScape provides is a very well-kept secret. We have very special-

Let’s make this. Let’s make it happen – simply and deliciously. Get the recipe at pork.org/cooking

ized services and there are still a lot of people who don’t know what we do. So that is something we need to address,

©2018 National Pork Board, Des Moines, IA USA. This message funded by America’s Pork Producers and the Pork Checkoff.

as well. ❖

EDITH SANFORD BREAST CENTER SYMPOSIUM FRIDAY, APRIL 5, 2019 DELTA HOTELS BY MARRIOTT, FARGO Please join us and other national breast cancer experts as we share the latest advancements in genetics, prevention and detection, surgery, treatment and survivorship.

011004-00734 11/18

Cost is $50; a reduced rate of $25 is offered for Sanford employees and students.

For more information, visit edith.sanfordhealth.org/symposium or email edithsymposium@sanfordhealth.org. Registration deadline is Friday, March 29.


Happenings around the region

News & Notes

South Dakota | Southwest Minnesota | Northwest Iowa | Northeast Nebraska

AVERA

BLACK HILLS

STEVE LINDQUIST Avera Health has named former behavioral health assistant Vice President Steve Lindquist as the leader of a new project aimed at combating the opioid epidemic through a one-year planning grant from the Health Resources & Services Administration (HRSA). Lindquist served at the helm of the Avera Behavioral Health Center for nearly 20 years. Previously, he was director of Mental Health for the State of South Dakota, as well as administrator of the George S. Mickelson Center for the Neurosciences. Lindquist has served on state task forces for managed care, telemedicine, and behavioral health and is a past president of the South Dakota Chapter of the National Association of Social Workers.

10

BROCK SANDERSON Brock Sanderson, RN, BSN, in the intensive care unit at Regional Health Rapid City Hospital, has been recognized with the prestigious DAISY Award for extraordinary nursing. Sanderson was nominated by a patient’s family member who recognized his ability to comfort the patient and his family, educate them on the patient’s care plan, and care for the whole family – not just the patient.

ERIC THOMPSON Eric Thompson, MD, has joined the Urgent Care team at Rapid City Medical Center. Dr. Thompson is board-certified in Family Medicine. He earned his medical degree from the University of North Dakota School of Medicine and Health Sciences and did his residency at the UC Davis in Redding, california. Dr. Thompson comes to Rapid City from Sanford Health in Bismarck and will join Drs. Michael Rafferty and Gary Welsh at Rapid City Medical Center’s Mt. Rushmore Road location.

Regional Health Medical Clinic in Rapid City held an open house and ribbon cutting in November for its new Genius 3D Mammography system. 3D mammography captures multiple slices of the breast, all at different angles. The three-dimensional technology allows radiologists to better detect breast cancer deep within the tissue, where it might be hidden during a traditional two-dimensional mammogram.

MidwestMedicalEdition.com


Regional Health recently got a new high-fidelity patient simulator through a grant from The Leona M. and Harry B. Helmsley Charitable Trust. This equipment adds obstetric care and labor and delivery training to the Simulation in Motion South Dakota (SIM-SD) program. Regional Health now has an adult male, two children, and an OB simulator that can give birth and simulate various obstetrical emergencies including breach delivery, precipitous delivery, and shoulder dystocia.

January / February 2019

Regional Health Lead-Deadwood Hospital has launched a new pilot project called the Lead-Deadwood Community Paramedicine Program, which expands the role of paramedics to help medically vulnerable patients stay at home and out of the hospital. When a patient is deemed a good fit for the program, a specially-trained paramedic goes to the patient’s home after discharge to take their vital signs, go through medications, draw blood and perform other services. The paramedic also evaluates whether prescriptions are correct and whether additional resources are needed and puts the patient in touch with the appropriate agencies.

SANFORD Sanford Health’s newest multispecialty clinic near S. Ellis Road and W. 32nd Street in Sioux Falls hosted a public open house on December 1 and opened on December 3. Staff members formerly at the 41st and Sertoma clinic have relocated to the new clinic. The 42,000 square foot facility includes more than 50 exam rooms for family medicine, children’s, OB-GYN and allergy services plus six procedure rooms and lab services. Patients will have the option to meet with genetic counselors, integrated health therapist and health coaches in private consultation rooms. A Lewis Drug store and pharmacy is attached.

11

• Happenings around the region

News & Notes


Happenings around the region

OTHER PILAR DE LA PUENTE A Sanford Health researcher recently won a Lush Prize for her work with breast cancer tumors. Pilar de la Puente, PhD, is looking for advances in technology and patientderived 3D-cell culture models to study breast cancer, rather than using animal tissue, which fails to provide an adequate model for recreating the complexities of human tumors. She plans to better understand the biology of drug resistance in breast cancer and the structure and function of the tumor microenvironment. (more on pg. 19)

12

Paul Hanson (second from left in photo), president of Sanford Sioux Falls and representing Sanford Health, recently accepted an appreciation award for Sanford’s support of residency programs from medical school officials including Nedd Brown (far left), associate dean of graduate medical education at USD Sanford School of Medicine, Dr. Michael Koch, chair of the medical school’s pathology department, and Dr. Mary Nettleman, dean of the medical school. The award was presented at the 60th anniversary celebration of the pathology department’s residency program. About 77.5 percent of USDSM graduates who do residencies in South Dakota stay in South Dakota to practice.

Ear, Nose & Throat Associates joins Yankton Medical Clinic, PC, on January 1. David Abbott, MD, and Micah Likness, MD, specialize in the diagnosis and management of diseases in the fields of allergy and sinus disease, facial plastics and reconstructive surgery, voice and swallowing disorders, thyroid and parathyroid disease, and sleep disorders including sleep apnea, facial trauma, allergy, otology and head and neck surgery. Audiology services are also offered. Ear, Nose & Throat Associates will continue to practice in their current locations in Yankton and Norfolk, Nebraska.

MidwestMedicalEdition.com


JASON R. HOWE Audiologist Jason R. Howe, M.S., FAAA, CCC-A, of Yankton Medical Clinic, PC, recently attended the Academy of Doctors of Audiology Annual Convention in Orlando, Florida. Among the topics discussed were comorbidity of hearing loss with a variety of conditions including moderate kidney disease, diabetes, balance disorders and arthritis. The group also addressed the association between hearing loss and cognitive decline and the importance of collaboration with primary care providers.

LORNELL E. HANSEN Dr. Lornell E. Hansen of Physicians Vein Clinics has been appointed to the American College of Phlebology’s Healthcare Advocacy Committee. The committee provides strategic direction to ACP leadership, and directly advocates for members in the areas of Federal and state policies, reimbursement, coding, carrier relations, vein education, and practice management. Based in Chicago, the ACP is dedicated to advancing clinical research, advocacy, and serving members who treat patients with venous and lymphatic medical conditions.

Prairie Lakes Healthcare System recently upgraded its cardiac catheterization lab. The cath lab installed a Phillips FD10 X-ray machine with a clarity package which offers high quality imaging with lower radiation levels. A boom with 6 screens was replaced by one large screen allowing up to eight inputs. Cath lab services include angiography, interventional procedures that restore circulation, and stent, pacemaker, defibrillator, and heart failure monitor placements.

Prairie Lakes cardiologists Dr. Salem Maaliki, Dr. Evelio Garcia, and Dr. Steven Miller

According to the personal finance website WalletHub, one of the states in the MED territory is among the 20 fattest states in the country. Iowa ranked number 18 on the list and fell between North Carolina (17th) and Maine (19th). Mississippi was number one with the highest number of obese residents. WalletHub released the report in November as part of National Diabetes Awareness Month. Find the full infographic at http://wallethub.com/blog/ diabetes-statistics/41253/

BRANDON HAGGERTY Brandon Haggerty, CISSP, has joined NorthStar Technology Group as a Director of Security and Professional Services. Haggerty has 8+ years of experience in healthcare risk management, vulnerability assessment and penetration testing, information security awareness programs/ training, HIPAA compliance, incident response, and social engineering.

January / February 2019

13

• Happenings around the region

News & Notes


Leading the Way in QA: Dakota Lions Sight & Health BY ALEX STRAUSS

D

AKOTA LIONS SIGHT & HEALTH

recognized by the associa-

in Sioux Falls is taking its mission

tion as being experts in

to restore sight and health to the

several areas of QA.”

rest of the country through the

One of Arnett’s first

work of its Chief Quality Officer, Matthew Arnett.

orders of business as chair

“At DLSH, I am responsible for quality policies

was to initiate the EBAA’s

and directives with the ultimate goal of assuring

first Quality Assurance

the safety and quality of the tissue that we recover,”

seminar, a concept that

Arnett told MED. “Everything we do is to make sure

had been in the works for

that the tissue is effective, safe, and suitable for the recipient.” DLSH Chief Quality Officer Matthew Arnett led six of the 13 presentations at the EBAA's first Quality Assurance Seminar in September.

several years. The EBAA already offers a similar training for recovery techni-

Arnett has been a member of the Quality Assur-

cians–those people who recover donated tissues–but,

ance Committee of the Eye Bank Association of

until now, there had not been a national level con-

America (EBAA), the accrediting organization

tinuing education opportunity for those who do what

which certifies eye and tissue banks like DLSH,

Arnett does.

since 2015. This June, at the group’s annual meeting, he became its chair.

“The FDA requires that every eye bank have two sides,” says Arnett. “There is a technical side and a

“I think being selected for this position is a

quality assurance side. So we knew there are people

recognition that we have a good quality program

in every eye bank in the country that could benefit

here in South Dakota,” says Arnett. “It reflects that

from learning and hearing about best practices from

we have a strong QA program and that we are

others.” In September, Arnett was one of three presenters and taught six of the 13 presentations at the first EBAA Quality Assurance training. More than 50 QA experts from eye banks around the US and Canada gathered in San Antonio to hear what’s working, what’s not, and to strategize ways to maintain the highest quality standards among member eye banks. “To a certain extent, eye banks compete with each other,” says Arnett. “So it was especially exciting to see everyone there being mission-focused and dedicated to improving their own programs by sharing and working together. We had some great roundtable discussions.” Arnett presented on topics ranging from handling complaints to information sharing, document control, and OSHA considerations. DLSH has maintained top level accreditation with the FDA, EBAA and the American Association of Tissue Banks (AATB). Arnett has been with the organization since 2013. ❖

WEB EXTRA

Read More

❱ Learn how DLSH makes things easier for surgeons with cutting edge tissue prep

14

MidwestMedicalEdition.com


I wish to go to Japan Jessica, 12

gastrointestinal disorder

HELP WISH KIDS TAKE FLIGHT Donate your unused airline miles from Delta or United to help make travel wishes come true for South Dakota children facing critical illnesses. Watch KSFY-TV and NewsCenter1 on February 28 to donate miles or cash during our statewide campaign, or donate anytime at southdakota.wish.org.

Call 800.640.9198 or donate online at southdakota.wish.org

Compassion . Experience . Trust  � � � �  ­ 605.334.1930 6301 S. Minnesota Ave., Suite 300 www.plasticsurgerysiouxfalls.com January / February 2019

15


Sanford’s First Lorraine Cross Award Katherine High Winners Dr. and Dr. Jean Bennett BY ALEX STRAUSS

T

HE DEVELOPERS of the very first

THE PROCESS

FDA-approved gene therapy drug for

To help streamline the process of wading through

a specific form of blindness were

thousands of research papers, Sanford used a com-

named

Sanford

puter algorithm to identify potential “hot topics”

Health’s inaugural Lorraine Cross Award in

from the year’s published studies. The original 72

December. The gala award ceremony at Sanford

topic areas were whittled down to 58 which were

Foundation Headquarters on December 4th was

then presented to the Sanford Scientific Advisory

the culmination of a year-long process that

Board, a 12-member board headed by Pearce and

involved dozens of people, hundreds of hours,

comprised of both MDs and PhDs.

the

winners

of

and a unique, sophisticated computer algorithm. top left Dr. Katherine High, President and Head of Research & Development, Spark Therapeutics top right Dr. Jean Bennett, F.M Kirby Professor of Ophthalmology and Cell & Developmental Biology, University of Pennsylvania, Perelman School of Medicine

16

As David Pearce, PhD, executive vice president of Innovation and Research at Sanford told MED, “The whole notion was that we wanted to have a different type of award. We wanted to find someone who had taken an idea beyond the bench, beyond the bedside, and actually used it to treat disease. And we wanted to use an entirely agnostic process to identify that person.” In the end, two longtime collaborators, Dr. Katherine High and Dr. Jean Bennett from Pennsylvania, took home the $1 million prize, elevating the cause of gene therapy and simultaneously helping to secure Sanford’s standing as a significant player within the international research community.

MidwestMedicalEdition.com


Photos by Lawrence & Schiller

“Ours was the first gene therapy for a genetic disease, but we know that there are other very exciting things coming down the pipeline in the area of gene therapy,” says High. “The whole point of the Human Genome Project was to identify all of these genes and use that knowledge to expand the therapeutic options for people with various genetic diseases. So I think it was a very timely decision for Sanford to recognize gene therapy.” The collaboration between High and Bennett began Sanford has adopted the Lorraine Cross as the symbol of innovation in healthcare

in 1990 when the two met at a gene therapy seminar and bonded over their shared interests and backgrounds. Bennett was testing gene therapy in dogs with Leber’s congenital amaurosis and seeing a 99% response rate. High was researching hemophilia. Although the two were working independently,

Eventually, the list of topics was narrowed to 20,

they reunited when High recognized the potential

then 14, and finally, just three. “At this point, we hadn’t

in Bennett’s work and helped her secure funding for

even talked about individuals yet,” says Pearce. “But

a human trial. With money from the Children’s

it was already quite clear that gene therapy stood out

Hospital of Philadelphia, the first human trials of

above everything else.” Pearce says gene therapy was the top choice not only because of its tremendous potential impact on human lives, but also because there were no other major prizes specifically recognizing innovation in this field. Once the topic was selected, certain individual gene therapy researcher candidates rose to the top of the pack. Along with Drs. High and Bennett, the finalists included Brian Kaspar, PhD, who discovered a gene replacement therapy for spinal muscular atrophy and James Wilson, MD, PhD, who helped define scientific and ethical standards for gene therapy testing. The Sanford International Board, comprised of business executives, philanthropists, and celebrities, was tasked with choosing the final winner after meeting with each of the nominees. “We were looking for those who really had what we saw as a ‘finishing mentality’,” says Pearce.

the new gene therapy treatment began in 2007. Luxturna proved to be just as effective in humans as it

THE WINNERS

had been in dogs and was approved in 2017.

Lorraine Cross winners Dr. Jean Bennett, a professor

“For us, the partnership worked because we both

of ophthalmology at the University of Pennsylvania’s

had confidence in each other’s judgment,” says High.

Perelman School of Medicine, and Dr. Katherine High,

“There are days when you feel like you’re just not

President and Head of Research & Development at

going to make it. And the other person will say, no

Spark Therapeutics, clearly had that mentality.

we’re going to make it. We’re closer than you think

The two had not only worked together for decades

Lorraine Cross candidates met personally with members of the Sanford International Board before the board made its final selection.

we are. We have both played that role over the years.”

to develop a gene therapy for the RPE65 mutation behind inherited retinal disease, but had also taken

THE FUTURE

that idea all the way through to human trials, the

While the $1 million Lorraine Cross award is a boon

formation of a company (Spark Therapeutics), and

for the recipients, as well as for genetic research, it

FDA clearance of Luxturna, the very first approved

has also been a win for Sanford’s global brand.

gene therapy.

January / February 2019

The prize brought a number of significant

17


Exceptional care.

High and Bennett received their award at a gala ceremony at Sanford Foundation headquarters on December 4th.

researchers into Sanford’s sphere of influence and put Sanford on the radar of other major players in the international research community. Pearce says the unique selection process ran surprisingly smoothly for a first time and, just as importantly,

Right here.

proved that the concept, and the algorithm designed to support it, are sound. “The take-home is that this was a purely agnostic process,” says Pearce. “This was novel. We do take nominations, but at the end of the day

AND HERE.

Dakota Dunes, SD Ponca, SD Vermillion, SD Norfolk, NE Pender, NE Wayne, NE Cherokee, IA

AND HERE. Dennison, IA Hawarden, IA Ida Grove, IA Lake City, IA Le Mars, IA Moville, IA Onawa, IA

AND HERE.

Orange City, IA Primghar, IA Sac City, IA Sioux Center, IA Sioux City, IA Spencer, IA Storm Lake, IA

it was an impartial assessment of these different research areas. This is really significant. I’m somewhat exhausted but I’m thrilled with the result.” After a few weeks to “debrief”, the wheels will be set in motion for the next Lorraine Cross Award in two years. In the meantime, Pearce says he hopes to publish a paper on the unique methodology behind the prize selection process. As for the Jean High and Katherine Bennett, both have philanthropic plans for at least part of

Schedule an appointment today. CNOS.net | 605-217-2667

their winnings. But both will also soldier on in their work, looking for the next genetic breakthrough Spark Therapeutics can help bring to market. “You have to do science because you love it,” says High. “It is not really something that people do for prizes or for financial reward or recognition. It really has to come from within because it is a very harsh discipline. But I have found it to be endlessly interesting. When things work, there is almost nothing better.” ❖

18

MidwestMedicalEdition.com


[ RESE ARCH ]

SIOUX FALLS RESEARCHER WINS AREA’S FIRST LUSH PRIZE

L

IKE MOST RESEARCHERS ,

Researcher prizes. De la Puente is one of only

Pilar de la Puente recognizes

four US researchers to win and the first one

the value of animal research.

ever from Sanford, the Dakotas, or Spain.

But it’s the fact that her lab

“In the end, when I won, I thought this is

has found an even more effective way to test

something incredible,” says de la Puente. “This

breast cancer treatments that attracted the

is the first one from Spain so my country is

attention of the Lush Prize, an organization

making a super big deal about it. There is news

that promotes animal-free testing.

all over the radio and everything.”

De la Puente is using patient-derived 3D

The Lush Young Researcher Prize carries a

cell culture models rather than animal tissue

£10,000 reward, which de la Puente will use to

to better understand the biology of drug resis-

take her research on patient-derived cellular

tance as well as a the structure and function

matrices to the next level.

of the tumor microenvironment.

“We will start with a retrospective study

“Not all breast cancers are identical. We try

to confirm that the predictions we are making

to treat all patients equally. That is a mistake.

based on the tumor models we create are accu-

We want to develop a treatment for that specific

rate,” says de la Puente. “Hopefully, within a

patient,” de la Puente told MED. “The idea is

couple of years, we will be able to start telling

that because we are recreating that specific

clinicians what to give the patient.”

tumor, we can test hundreds of therapies and

The annual Lush prize is the largest in

hundreds of combinations and say what one

the non-animal testing sector, and it is the

will work for that patient, at that moment, with

only award to focus solely on the complete

those specific genetics.”

replacement of animal tests. De la Puente

Thirty-three-year-old De la Puente, who is

says she hopes her win will inspire others in

from Spain, started at Sanford in Sioux Falls

our region to consider applying for interna-

in June. She was familiar with the UK-based

tional awards. “This could open the doors for

Lush company but was thrilled and surprised

people to do some new kinds of research,”

to be nominated for one of this year’s 13 Young

she says. ❖

January / February 2019

“ NOT ALL BREAST

CANCERS ARE IDENTICAL. WE TRY TO TREAT ALL PATIENTS EQUALLY. THAT IS A MISTAKE.

19


USD student researcher Kylie Vandry in Ghana

SUSTAINABLE HEALTHCARE in developing countries requires regular education, adequate access, and government support. When agencies and governments need to make informed decisions about these issues, they can turn to an unlikely resource: university student research. Dr. Carole South-Winter and her Health Services Administration students at the University of South Dakota have been conducting and publishing research for Sanford World Clinic for six years. It started with opinion leadership and patient satisfaction and in May 2018, student investigators were tasked to discover how long patients are willing to wait in line for healthcare, and learned that some will wait as long as three days. This survey also provided information to Sanford regarding new clinic location. Supply chain management is essential, requiring a challenging level of managerial skill throughout the process. Second, research shows a strong correlation

OVERSEAS RESEARCH EXPANDS WORLD VIEW FOR USD STUDENT SCIENTISTS

between a deficiency of healthcare workers and lower healthcare quality; it is common for outsiders to provide well-intentioned “Short Term Medical Brigades” to developing countries. This method does not fix the healthcare system and can actually create problems with continuity, finances, and cultural barriers (Portman & Martin, 2015). Investment in the local workforce by hiring indigenous profes-

The following article was provided by

sionals promotes cultural understanding

Dr. Carole South-Winter, Assistant Profes-

and sustainable success. (South-Winter &

sor Health Services Administration at the University of South Dakota as a summary of the research she and a group of HSAD

Tihart, 2018). Finally, education is paramount to building sustainable healthcare in developing countries, but —as

students have been involved in overseas

South-Winter’s research shows— that

for the past six years.

education is mutually beneficial. Student researchers survey healthcare needs, conduct blood sugar and blood pressure checks, and teach the importance of handwashing and dental hygiene.

A student researcher conducting house-to-house healthcare surveys in Ghana.

20

MidwestMedicalEdition.com


“Allowing students to be a part of the research process within the Sanford World Clinics is an amazing way to experience first-hand just how important the work is,” says student researcher Kylie Vandry. “It was a major learning experi-

Mediterranean-Style

Lean Beef

Eating with Supports a Healthy

ence for me to see the real-life differences

Heart

Recent research demonstrates that following a Mediterranean-style eating pattern that includes up to 18 ounces of cooked, fresh lean beef and pork per week – along with poultry and fish – is just as effective at improving certain heart disease risk factors (such as blood pressure and total and LDL cholesterol) as a Mediterranean-style eating pattern that limits red meat.1

in each clinic’s healthcare facility and their services. As a student who plans on entering the healthcare field, the opportunity to conduct research in a developing nation has increased my passion and overall desire to help communities, such as the ones we visited.” The most effective health initiatives provide free and equal access, especially to primary care, which is the greatest need in developing countries. Health systems are partnering with others dedicated to improving global healthcare, not least of

BeefItsWhatsForDinner.com/newsroom/Mediterranean-Diet

these are university programs and student

1

researchers.

Report of the Dietary Guidelines Advisory Committee on the Dietary Guidelines for Americans, 2015. Available at https://health.gov/dietaryguidelines/2015-scientific-report/PDFs/Scientific-Report-of-the-2015-Dietary-Guidelines-Advisory-Committee.pdf A Mediterranean-style eating pattern with lean, unprocessed red meat has cardiometabolic benefits for adults who are overweight or obese in a randomized, crossover, controlled feeding trial. Am J Clin Nutr 2018, nqy075. https://academic.oup.com/ajcn/article/108/1/33/5036105

* Fresh meats were defined in the study as requiring no further preservation or processing beyond refrigeration or freezing; they are not cured, salted or smoked or include chemical preservatives.

By participating in such outreach experiences, this next generation of healthcare professionals learns handson skills necessary to create a healthier world. As graduate student Jeremy Coss summarized, “The unique part about this experience is that we, the students, conducted our own research regarding material that we learned in the classroom. This research opened an entire new view on my education & has enhanced my world view.” ❖

WEB EXTRA

Read More

Be relentless in support of women’s health.

Wear Red 02 01 19 Locally presented by

Read the full research article on our website. Locally sponsored by

REFERENCES Portman, MT, & Martin, EJ, (2015). “Medical Brigades, Global Health and the United Nations: Millennium Development Goals and Developing Nations”, Journal of Health & Human Services Administration, 38(1), 90-107. South-Winter, CA, & Tiahrt, T, (2018). “Opening Clinics in the Developing World”. Global Journal of Business Disciplines (GJBD), Institute for Global Business Research (IGBR), 562

©2018 MWA American Heart Association. Also known as the Heart Fund. Go Red TM AHA. Red Dress TM DHHS.

2019_DAK_WRD_Ad_4.6x4.6.indd 1

January / February 2019

11/28/2018 1:31:12 PM

21


January 20, 2019 • 2 p.m. When JASON FARNHAM takes the stage on piano, you’ll get to enjoy a mix of contemporary and classic piano pieces, along with some originals. This is more than just your average piano performance, so make sure you’re here to see all the surprises!

Tickets start at $25*/adult and $15*/youth Experience Your Washington Pavilion 301 S. Main Ave. Sioux Falls, SD 605.367.6000 | washingtonpavilion.org

*Tax not included. Programs, dates, times and prices subject to change.


January, February, March, April, May

UPCOMING EVENTS JANUARY 7

MARCH 8

5:00 pm

8:00 am – 4:00 pm

Grand Opening Event Location: Regional Health Orthopedic

12th Annual Avera Brain and Spine Institute Conference

& Specialty Hospital

Location: Hilton Garden Inn,

Information: 605-755-9178

Downtown Sioux Falls Information and Registration:

FEBRUARY 1–8 UnityPoint Health Mid-Winter Medical Education Conference Location: Fairmont Orchid, Big Island, Hawaii

averacontinuingeducation@avera.org 605-322-7879

APRIL 5

Registration: 800-441-1414

9:00 am – 6:00 pm

(by Jan. 1 for discounted rate)

Edith Sanford Breast Center Symposium

FEBRUARY 2

Location: Delta Hotel by Marriott, Fargo

8:00 am – 4:00 pm Sanford Neuroscience Symposium

MAY 15

Location: Delta Hotel by Marriott, Fargo, ND

8:30 am – 4:00 pm

Early bird registration until January 21

Avera Caring Professionals Conference

SanfordHealth.csod.com

Location: Sioux Falls Convention Center

FEBRUARY 22–23

Information and Registration:

8:00 am, Friday – 4:00 pm, Saturday

605-322-7879

averacontinuingeducation@avera.org

39th SD Conference in Emergency Medicine

MAY 16

Location: Hilton Garden Inn, Sioux Falls

1:00 pm – 2:00 pm

Information: sdacepconference.com

Sanford Imagenetics Lecture Series Location: Schroeder Auditorium, Sanford USD Medical Center

VISIT THE ONLINE CALENDAR at MidwestMedicalEdition.com to find more information on these and other upcoming events between issues. You can also add your own event to the calendar for free.


DR. JEAN BENNETT & DR. KATHERINE HIGH

2018 SANFORD LORRAINE CROSS AWARD WINNERS When innovation wins, we all win. Meet Dr. Jean Bennett and Dr. Katherine High, who’ve collaborated for more than a decade to develop the first FDA-approved gene therapy drug to cure a genetic form of blindness. For this groundbreaking work, Dr. Bennett and Dr. High are the 2018 co-winners of the Sanford Lorraine Cross Award, a $1 million medical honor that rewards the finishers changing the face of medicine. Congratulations, and here’s to a visionary future.

Learn more about Dr. Bennett and Dr. High at SanfordLorraineCross.com


Issuu converts static files into: digital portfolios, online yearbooks, online catalogs, digital photo albums and more. Sign up and create your flipbook.