The difficulty in diagnosing hypertrophic cardiomyopathy. . 2021. https://pcna.net/the-difficulty-indiagnosing-hypertrophic-cardiomyopathy/. Accessed Jul 21, 2023.
Summarized as an imbalance in Starlings forces or an imbalance in the degree of end-diastolic fiber stretch proportional to the systolic mechanical work expended in the ensuing contraction
Pathophysiology
Or basically like a rubber band, the more it is stretched, the greater the releasing velocity
Depression of Ventricular function
Stretching of myocardial fibers (STARLING’S LAW)
Ventricular dilatation
Left Ventricle Failure
• Ischemic Heart Disease
• Valvular Heart Disease
• Pericardial Restriction
• Myocarditis
Right Ventricle Failure
• Right Side Valvular Disease
• Right Side Myocardial Disease
• Cor Pulmonale
• Pulmonary Hypertension
Compensation Mechanisms Activation
Tachycardia
Etiology
• Coronary artery disease-chronic, post MI
• HTN
• Chronic Valvular heart disease (especially aorta and mitral disease)
• Acute Infection viral myocarditis
• Dysrhythmias
• Alcohol-chronic
• Long standing Diabetes
Concept Of Preload And Afterload
Preload
• The amount of blood the heart must pump with each beat
• Determined by:
• Venous return to heart
• Accompanying stretch of the muscle fibers
• Increasing preload → increased stroke volume in normal heart