Australian Pain Society Newsletter
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Editor’s Note
Dr Lincoln Tracy
It’s hard to believe there’s only six weeks until the Annual Scientific Meeting (ASM) in Melbourne –it doesn’t seem like it was that long ago that we were all in Darwin!
The Australian Pain Society (APS) ASM is always a great conference, and the program for this year looks like it will continue that trend. And while I am excited that the ASM will be in my home city of Melbourne this year, this excitement is also somewhat tinged with sadness as it marks the point where I will step down as Editor of the eNewsletter – making this my last Editor’s note.
I would like to use this opportunity to thank everyone who I have worked with during my time on the eNewsletter team. I first joined the team in September 2018, serving as the assistant editor to Stephanie Davies. Joanne Harmon came on board in early 2020 after I took over as editor from Stephanie.
The Secretariat does an amazing job at keeping things running smoothly behind the scenes, and it’s safe to say that I couldn’t have done this job for so long without their assistance. Looking back at emails over the years reminded me of some of the names in the early days of the role, and I hope I’m not forgetting anyone, but to Tracy Hallen, Kylie Dark, Sunny Sun, Vanessa Lane, and Kristy Gorenc – thank you deeply.
The APS Board and its different presidents – Anne Burke, Trudy Maunsell, and Joyce McSwan –also deserve a big thank you for their ongoing support and encouragement. Not only has reporting to the Board during my time in this role has given me a new level of appreciation for all of the work that goes into running a society like the APS, but everyone in those meetings went out of their way to make me feel welcome. I’d like to give my best wishes to Bernadette Smith, who will replace Joyce as President later in the month.
This edition of the eNewsletter has all the features you are used to – excellent summaries of recent publications from the Basic Pain Research SIG and members sharing their work – but it also includes three glowing reports from the painSTAR 2024 attendees. If you’re new to the society, or have somehow never heard about painSTAR, check them out.
Looking forward to seeing you all in Melbourne for the ASM next month!
Lincoln
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President’s Report
Joyce McSwan
Hello APS Family!
What an incredible journey the past two years have been as President of the Australian Pain Society (APS). It has been a period of growth, learning, and immense appreciation for the APS and its remarkable members. Serving in this role has been both an honour and a privilege, and I am deeply grateful for the opportunity.
Throughout my tenure, I have witnessed firsthand how the APS stands as a leader in pain management, both nationally and internationally. Our Society is held in the highest regard, thanks to the unwavering dedication of our members— practitioners, researchers, and advocates—who are committed to advancing pain management. It has been particularly inspiring to see the enthusiasm of our emerging health professionals, eager to contribute to the field and drive innovation.
At the heart of the APS’s success are our members, including world-renowned experts who generously share their knowledge and expertise. Their contributions have been instrumental in shaping the future of pain management, and we are immensely grateful for their ongoing commitment.
Reflecting on the past two years, I am particularly proud of the progress we have made in strengthening our Annual Scientific Meeting and introducing key initiatives such as our mentoring program. Our contributions to pain management in aged care have been reinforced through the completion of the online education program, painACT, and painSTAR continues to flourish as a leading program for translation and research. These initiatives highlight the APS’s commitment to fostering education, collaboration, and innovation in pain management.
Enhancing the value of APS membership has remained a priority, ensuring that our activities provide tangible benefits to our members. The APS continues to lead by example, advocating
for best practices and supporting our community through education and research.
A thriving Society depends on the engagement of its members. I encourage all those interested in contributing to APS activities to step forward and share their passion. There are many opportunities to get involved, and your contributions—big or small—play a vital role in the Society’s ongoing success. The APS is a welcoming place for professionals at all career stages, offering mentorship and support to those eager to deepen their involvement.
Following this year’s Annual General Meeting, we will welcome four new members to the APS Board. I look forward to onboarding them and have no doubt that their expertise will serve the Society well. I am also honoured to have worked alongside our incoming President, Bernadette Smith. Her thoughtful leadership and exceptional governance skills will undoubtedly strengthen the APS in the years to come, and I am confident that under her guidance, the Society will continue to thrive.
As I transition into the role of Immediate Past President, I remain committed to the APS and am always available to support members who wish to connect.
Finally, I extend my sincere thanks to each of you for your support, dedication, and passion for advancing pain management. Serving as your President has been an extraordinary experience, and I am grateful for the trust you have placed in me. Together, we have achieved great things, and I am certain that the APS will continue to lead with excellence in the years ahead.
Thank you once again for this incredible opportunity.
Warm regards,
Joyce McSwan President, Australian Pain Society
Calling for Newsletter Editor EOIs!
We extend our heartfelt thanks to Dr Lincoln Tracy for his dedication and support as our Newsletter Editor over the past seven years.
Lincoln has made invaluable contributions to our team by formalising the newsletter structure and schedule.
It is with sadness that we say goodbye, and we wish him all the best in his future endeavours.
We are now seeking Expressions of Interest (EOIs) to fill the role of Newsletter Editor, supported by our Assistant Editor.
About the Role:
The Editor's key responsibilities include:
• Reviewing and editing newsletter content to ensure consistency and readability.
• Writing an editor's note at the beginning of each edition (five times per year, alternating with the Assistant Editor) to provide insights on current topics in the pain field or highlight key newsletter content.
• Attending the newsletter topic only at board meetings (mostly online, with one inperson meeting at the ASM each year) to update the board on newsletter activities and receive feedback.
• Chairing eNewsletter team meetings (twice per year) to guide content strategies and initiatives.
What You’ll Gain:
• Valuable volunteer experience to enhance your CV for promotions or grant applications.
• A platform to share your insights with our membership and wider readership.
• Opportunities to review new pain-related books before their official release when requested by the APS.
• A chance to network and develop a broader understanding of the society.
We publish 10 editions annually, with eight more newsletters scheduled through December 2025.
If you’re interested, please submit your EOI to the APS Secretariat at aps@apsoc.org.au.
Joyce McSwan APS President
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6 WEEKS TO GO! REGISTER TODAY!
Have you secured your place at Australia’s only multidisciplinary conference?
The conference offers insights into the complex nature of pain management from a variety of medical, nursing, research, and allied health perspectives.
Don’t miss out on your opportunity to join us this April in Melbourne, VIC.
Please click here to register
Considering the benefits of APS membership?
Become a member and save on your APS 2025 registration fee!
Early Bird Deadline Register before 8 March 2025
Non-Member Registration Price VS
Becoming an APS Member $1,625 OR
Being a member saves you up to $550 after membership fees!
APS Student Member Registration Price Only $350 Being a member saves you $1,180 after membership fees!
Tell your colleagues who are interested in becoming members so they can save on their registrations too!
Become an APS Member here!
Should you have any queries about the conference, please contact the Conference Secretariat
PROGRAM OVERVIEW
2025 will bring us more challenges in the IASP Global Year about Pain Management, Research and Education in Low- and Middle-income Settings
You can look forward to an extensive program including seven pre-conference workshops, plenary sessions including international keynote speakers and national leaders in the field of pain, 24 topical sessions, and three social functions.
Yes, that’s right – 24 topical sessions!
Thanks to a record number of submissions received, the APS is delighted to confirm the ASM program in 2025 has been extended to include an additional stream of concurrent topical sessions.
The program will run until 5pm on Wednesday afternoon – ensuring delegates have access to more content, more speakers, and more opportunities to connect than ever before.
Follow the links to start planning your conference experience today!
Program Overview
Keynote Speakers
Panel Discussion: Psychedelics in Pain
Pre-Conference Workshops
Topical Concurrent Sessions
Free Paper Sessions
Meet the Minds Sessions
Social Program
For information on APS 2025 visit the conference website
We look forward to welcoming you to Melbourne, VIC!
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CONFERENCE SOCIAL PROGRAM
Social Program Explore the social program and plan your conference experience today:
Sunday 13 April 2025
Welcome Reception
Venue: Exhibition Hall, Pullman Melbourne Albert Park
Time: 6:00pm - 7:30pm
Dress: Smart Casual
Cost: Included in registration fee for full delegates and sponsors/exhibitors
Additional tickets: $60pp, guests welcome
Join us for a first look at the exhibition hall and a chance to catch up with colleagues and delegates you may not have seen since Darwin.
Basic Pain Research & Pain in Childhood SIG Dinner
Venue: The Windsor Alehouse, 42 Punt Road
Time: From 7:30pm, after the Welcome Reception
Dress: Smart Casual
Cost: $90 per person, guests welcome
The Windsor Alehouse is within walking distance of the Pullman, it has a cosy and wholesome vibe and offers craft beer, live music and delicious food.
Enjoy a two-course meal, plus drinks with friends and colleagues interested in Basic Pain Research and Pain in Childhood. Delegates don’t have to be a member of the SIGs to join, everyone is welcome.
Monday 14 April 2025
Social Activity
Venue: The Windsor Alehouse, 42 Punt Road
Time: From 5:30pm
Cost: Delegates will receive a complimentary drink card in their registration pack, no reservation is required.
An easy stroll after a long day of sitting, join fellow delegate at The Windsor Alehouse - a local pub that offers craft beers, wholesome meals, and space to network.
With a dedicated reserved space for APS delegates, join colleagues to wind down and recap on the days learning, over a complimentary wine or beer.
Tuesday 15 April 2025
Gala Dinner
Venue: Carousel, Albert Park Lake
Time: 7:00pm - 11:00pm
Dress: Smart/Cocktail
Cost: $150, guests welcome (transport included)
Join us to celebrate another fantastic ASM, enjoy a delicious meal and drinks - with plenty of time for dancing (of course!). The Gala Dinner is always considered a highlight of the conference, don't miss out!
Register Now! Secure your place at these enjoyable and entertaining social functions
Should you have any queries about the conference, please contact the Conference Secretariat
We look forward to welcoming you to Melbourne, VIC!
MEET THE MINDS: Q&A AND NETWORKING SESSION
Pick the brains of leaders in the field!
Join us at this exclusive Q&A and networking event designed for those looking to undertake a dive deep into the latest in pain research and clinical practice.
Engage in meaningful discussions, gain valuable insights, and establish new collaborations.
Whether you are a student, early or mid-career researcher, clinician, or just eager to learn, come along and connect with top minds and fellow attendees.
Date: Monday 14 April 2025
Time: 5:30pm - 6:30pm
Cost: $15 per person, includes a drink on arrival
When registering for the conference, don’t forget to add in a ticket to the Meet the Minds: Q&A and Networking Session!
To register click here.
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Morning Workshops
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Afternoon Workshops
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Full Day Workshop
painSTAR 2024 Report
Erin MacIntyre
Erin is in the final year of her PhD at the University of South Australia. She is interested in how technology can be harnessed to improve clinical outcomes for people suffering from pain.
I feel so grateful that I was able to attend painSTAR in the beautiful Barossa Valley. I was inspired to apply for painSTAR due to the positive experiences I’ve had at the previous trainee sessions at Australian Pain Society (APS) conferences and from rave reviews of previous alumni. My goals for attending painSTAR were simple – I wanted to build a network of fellow pain researchers and learn from the faculty of national and international experts. I can honestly say that after three action-packed days, I was able to achieve these goals and more!
It's hard to narrow down the best part of painSTAR 2024. Highlights included learning about basic science from the best (I have a new appreciation for how complex this work is), sessions dedicated to working with industry (from both a researcher and industry perspective), and how to deal with imposter syndrome and (try to) achieve work-life balance. I also enjoyed that we were able to be creative – from paint and sip to our pitch presentations. Beyond this, faculty and patient partners were involved for the duration of the program. They attended all talks and activities and had meals with us. Unlike most conferences or events, this
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allowed us time to get to know each other and build genuine connections. These connections have already paid off – I have already met with one of the other delegates to solve a tricky analysis problem that has been plaguing me for months!
I am also incredibly grateful that I was able to get to know a whole cohort of painSTARs. My fellow attendees shared their research throughout the week in a series of presentations. I was blown away by the quality and the breadth of the research people shared. This combined with the passion that attendees had for their work was seriously impressive. I am so excited to reconnect with my fellow painSTAR alumni this April in Melbourne (and beyond). I think that the future of pain research in Australia is very bright!
My experience at painSTAR exceeded all expectations. I want to thank the APS and the painSTAR faculty for providing this opportunity. The event was incredibly well organised, and perfectly balanced fun and learning. As an early career researcher, I feel so incredibly grateful for the opportunities provided to me by the APS. If you ever get the opportunity to apply for painSTAR – do it!
Declaration
Erin MacIntyre has nothing to declare.
L to R: Marina Vygonskaya and Erin MacIntyre
painSTAR 2024 Report
Caitlin Jones
Caitlin Jones is a postdoctoral research associate at the Institute for Musculoskeletal Health, the University of Sydney. Her research focus is investigating high-risk interventions for musculoskeletal pain that lack a supportive evidence base.
I have been going to Australian Pain Society (APS) conferences since the first year of my PhD, drawn in by the opportunity to mingle with people from diverse pain fields with diverse perspectives. The world of clinical musculoskeletal research, particularly back pain, is reasonably small and so I value the chance to hear from people who work in the different part of the research spectrum. I had heard of painSTAR through my APS connections, but didn’t really know what it entailed. I hoped it would be a small group of early career researchers, getting to know each other and each other’s work, being mentored by world class teachers, learning relevant concrete skills, expanding my network, and opening my eyes to the breadth of possibilities in pain research. It turns out, painSTAR was exactly that.
What I enjoyed most about painSTAR was that it was a small enough group that we got to know each other. It was on a different level to a typical conference where you might chat with a new person over a coffee for a few moments. This was four days of connecting over our shared interests, learning from each other (from both the other attendees and the expert faculty). I particularly enjoyed learning about
basic research, as that has felt completely inaccessible to me as a clinical researcher who knows NOTHING about it. Now I feel like I know just enough to strike up a conversation with a basic scientist and have a chat about how we can complement each other’s work.
Attending painSTAR has already changed my work by changing my mindset. My sense of where my career could go and how broad my collaborations could be feels at least three times as big as it was before. I have also already used the practical skills I learnt about research communication during my presentations since. That’s another benefit of the small group - that we got each got to get up and present our work and receive feedback from experts and the wider group. The feedback was directly relevant and immediately actionable.
I am looking forward to the APS conference in Melbourne because I can’t wait to catch up with the people I met at painSTAR. I feel more solidly a part of the APS community. I would highly recommend painSTAR to anyone who is in the early stages of a career in pain research and wants to improve their science communication, expand their network, feel inspired, and spend time among a community of warm and interesting people in a beautiful location.
Declaration
Caitlin Jones has nothing to declare.
painSTAR 2024 Report
Alison Sim
PhD Candidate, The University of Sydney. Alison is an osteopath who has worked in the area of chronic pain for many years. She has a master’s degree in pain management from The University of Sydney and has completed a PhD exploring early interventions following compensable injuries.
Reflections
on attending the painSTAR Conference
Being selected to attend the painSTAR conference was an incredible honour. Having heard such positive reports from past participants, I was excited to be part of this prestigious program and to engage with a group of highly motivated individuals. As I near the completion of my PhD, I saw painSTAR as a valuable opportunity to gain insights into the field of pain research, expand my professional network, and gain clarity on potential career pathways. My goals for the week were to build connections, learn from the experiences of established researchers, and develop a clearer vision of what a career in pain research could look like. I am pleased to say that each of these goals was met—and exceeded—throughout the week.
Highlights of painSTAR
The experience of painSTAR was truly enriching. One of the most significant takeaways for me was a strong sense of reassurance about the future of pain research. The attendees were not only intelligent and highly motivated but also collaborative, kind, and open to sharing their knowledge. It was inspiring to be surrounded by such a dedicated group of researchers and clinicians who are deeply invested in advancing pain science.
A key highlight was the faculty members—a generous and experienced group of leaders in the field who were genuinely invested in our future and in the mission of painSTAR. Their candid discussions about their careers,
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challenges, and successes were incredibly valuable. I particularly appreciated the sessions on burnout, working with industry, work-life balance, and grant writing, as they provided practical insights from seasoned professionals who have navigated the complexities of academia and clinical research.
Another standout experience was the group project, which pushed us out of our comfort zones and reinforced the importance of collaboration. Faced with what initially seemed like an impossible task, our team worked together by leveraging each other’s strengths, ultimately producing a strong project proposal. The process was both challenging and rewarding, and along the way, there were plenty of laughs. This exercise reinforced the power of teamwork and adaptability—key skills for any research career.
Beyond the academic and professional development aspects, the conference setting in the Adelaide Hills and Barossa Valley provided a perfect backdrop for deep learning and connection. The stunning scenery, incredible food and wine, and opportunities for outdoor activities created an environment that fostered both relaxation and engagement. The friendships and connections I made during this time will be just as valuable as the knowledge I gained.
Impact on My Research and Practice
Attending painSTAR has significantly shaped my understanding of what a career in pain research can look like. The discussions with faculty members helped contextualise the progress of the field, reinforcing the importance of building upon existing research to make meaningful contributions to improving patient outcomes. Their insights gave me a renewed sense of purpose and motivation to continue in research, with a deeper appreciation of its real-world impact.
painSTAR Delegate Report
On a practical level, I found the presentation and communication skills workshops particularly beneficial. I have already begun applying these techniques in my own presentations, and I believe they will enhance my ability to communicate complex ideas more effectively in both academic and clinical settings.
New Collaborations and Future Directions
One of the most exciting outcomes of painSTAR has been the opportunity to form new professional connections, which have already led to potential collaborations. These connections have expanded my network beyond my immediate research group and provided new avenues to explore in the future.
Final Thoughts
Attending painSTAR was an invaluable experience that has undoubtedly influenced the direction of my career. It not only deepened my passion for pain research but also provided me with practical skills, new collaborations, and a greater understanding of the diverse opportunities within the field. The support and encouragement from both faculty and fellow attendees have reinforced my confidence in pursuing a career in research, knowing that I am part of a community that values collaboration, innovation, and real-world impact.
I am incredibly grateful for this opportunity and look forward to applying the knowledge and connections I gained at painSTAR to my future work.
Declaration
Alison Sim has no declarations
Would you like to be featured in an APS member spotlight?
Email the APS Secretariat (aps@apsoc.org.au) if you would like to complete a short interview to introduce yourself and your work to the broader membership.
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Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes
Franco-Enzástiga Ú, Inturi NN, Natarajan K, et al. Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes. Pain. 2025;166(3):614-630, 10 July 2024
Reviewer: Dr Dusan Matusica, Group Lead - Pain and Sensory Cell Biology Lab, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, South Australia
DOI: 10.1097/j.pain.0000000000003509, March 2025
Review of article
Background
This article is a commentary on a research paper by Franco-Enzastiga et al., which investigates the differences in how genes are expressed in males and females, specifically focusing on the dorsal root ganglia (DRG). The DRG is a cluster of nerve cells in the spinal cord that plays a crucial role in transmitting pain signals from the periphery to the central nervous system and plays a critical role in the development of chronic pain. This study looks at how DNA accessibility in the DRG might explain why men and women experience pain differently.
Study group
The study examined DRG tissue from male and female human organ donors.
Aims of study
The primary goal was to understand how differences in the accessibility of DNA in the DRG contribute to variations in gene expression that may identify molecular differences in pain related processing and pathways between males and females.
Brief methodology
This study used a high-tech method called ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing). Think of DNA inside cells not as a naked strand, but as being wrapped around proteins called histones, forming a structure called chromatin. This wrapping can either hide DNA, preventing genes from being read, or expose DNA, allowing DNA and the genes embedded in it to be read. ATAC-seq is a way to map out the areas of DNA that are exposed ("accessible"). In simple terms, they used a special enzyme that only cuts DNA in the exposed regions. This enzyme also adds "tags" to the cut DNA. Then, they used a machine to identify the tagged DNA fragments, allowing them to detect which genes are accessible in the DRG cells of male and female human donors. More importantly, to understand in which DNA parts are accessible in which cell types, they used spatial ATAC. Spatial ATAC involves placing a thin slice of DRG tissue onto a special grid. This grid captures the DNA from individual cells, allowing cell-type specific identification of accessible genes within the DRG.
Brief summary of the results
The results show that about 15% of the accessible DNA regions were near the start sites of genes. They identified over 3000 regions where DNA accessibility differed between males and females. Interestingly, in females, many of these differences were on the X chromosome, while in males, they were on other non-sex linked (autosomal) chromosomes. They also found that females and males use different transcription factors (proteins that control gene reading) to read the DNA. Different transcription factors enable expression of different genes, related to things like nerve function, pain signalling, and the immune system. This consequently
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demonstrates that the accessibility and gene expression is differently controlled between sexes.
Conclusions
These differences could help explain why males and females experience pain differently.
Reviewers’ critique & take home message from the article
This study highlights the intricacies and important differences in the genetic processing of pain-related molecules in males and females. It marks a pivotal juncture in the search to unravel the genetic reasons behind sex differences in pain. While the sample sizes were small and sourced from donor tissues that have no history of chronic pain or neuropathy, this study opens an important avenue to critical insights into pain neurobiology. It clearly shows that sex differences in basic pain processing
in males and females are significant, and X chromosome-linked in females. More importantly, this work establishes the baseline platform for comparison with DRG tissues from chronic pain patients. The authors also demonstrate the utility of ATAC-seq and spatial ATAC as a powerful approach to understanding gene regulation in sensory neurons. The exciting message is that we are beginning to understand the genetic basis of pain differences between men and women, and further research in this area could lead to new approaches to diagnose and treat chronic pain.
Declaration
DM declares a collaborative partnership with the Pain Neurobiology Research Group led by Professor Theodore Price on unrelated projects, including co-authorship of a manuscript on structural DRG neurobiology that is currently under review.
Cerebellar Bergmann glia integrate noxious information and modulate nocifensive behaviors
Kim SH, Lee J, Jang M, et al. Cerebellar Bergmann glia integrate noxious information and modulate nocifensive behaviors. Nat Neurosci. 2025;28(2):336-345, 02 January 2025
Reviewer: Karin Aubrey - Laboratory Head, Pain Management Research Institute, Kolling Institute, Northern Sydney Local Health District & Adjunct Associate Professor, Kolling Institute, Faculty of Medicine and Health, The University of Sydney. E. karin.aubrey@sydney.edu.au
DOI: 10.1038/s41593-024-01807-z
Review of article
Background
The cerebellum is well recognised for its role in movement coordination and vestibular function. However, growing evidence suggests that it also plays a role in various cognitive processes.
Study group
The study was carried out in wild-type C57Bl/6N and genetically modified mice. The genetically modified organisms (GMOs) were Cre-lines that facilitated specific manipulation of astrocytes or cerebellar Purkinje cells. Acute pain was stimulated with noxious electrical stimulation of the hind paw or intraplanar capsaicin/mustard oil injection.
Aims of study
Pain processing involves multiple brain regions beyond sensory circuits, enabling appropriate responses to noxious stimuli. Functional MRI studies in both humans and mice consistently show cerebellar activation during pain states. However, the specific mechanisms by which the cerebellum contributes to pain signaling remain poorly understood.
This study aimed to investigate how peripheral noxious information is transmitted and processed within the cerebellum.
Brief methodology
The study used a dizzying variety of contemporary neuroscience techniques in combination with animal behaviour to address the studies aims. Neuronal activity of axon terminals from noradrenaline-releasing locus coeruleus (LC) projection neurons and glial was measured using 2-photo calcium imaging in the cerebellum, chemogenetics, optogenetics, pharmacology, gene expression knockdown with shRNA were used to manipulate behaviour/neuronal activity and this was complimented with field electrophysiology and GRABNE/calcium sensor recordings in brain slice. The combination is impressive and allowed the group to validate finding using multiple techniques.
Brief summary of the results
The authors directly demonstrate that noxious stimuli are sensed in the cerebellar cortex, showing that the terminals of LC projection neurons in the cerebellar cortex respond reliably to noxious stimuli. They also show that LC stimulation triggers slow calcium waves in Bergmann glia cells that is dependent on Bergmann glia α1-adrenergic receptors ( α1-AR) and linked to nocifensive responses. Bergmann glia sit close to the only output neuron in the cerebellum, Purkinje cells, and are known to modulate Purkinje cell activity. Finally, the authors demonstrate that α1-AR-mediated activation of Bergmann glia leads to changes the Purkinje cell outputs during pain, and that preventing Bergmann glia to Purkinje signaling is analgesic in a model of neuropathic pain.
Conclusions
Together, this work illustrates a mechanism for the cerebellum to sense and respond to noxious information and suggests it could be targeted to alleviate chronic pain symptoms. It convincingly elucidates an underlying mechanism by which the cerebellum is actively involved in the computation of the pain state.
Reviewer's critique & take home message from the article
This study stands out not only for its use of technology, but also for its strong evidence demonstrating how the cerebellum influences pain behaviors. Additionally, it highlights the critical role of type of glial cell in this signaling cascade.
The authors conducted multiple rigorous control experiments to validate their data and interpretations, all of which are included in the supplementary materials. While the study does not answer all questions regarding the cerebellum’s role in pain—such as how signals
are transmitted between the Bergmann glia cells and Purkinje cells, whether the proposed computational value of phasic and tonic noxious signaling hold in chronic pain states, or how these circuits interact with motor control circuits—it represents a significant – and well executed - advancement in the field. Importantly, it also generates a range of testable hypotheses. Future replication will be key to confirming these findings.
Declaration
Nothing to declare
Boost your career with a partial scholarship of $1,000-$5,000 from Women & Leadership Australia. Choose from one of four leadership and workplace skill development courses for women at all levels in Health.
Apply by Friday 28 March 2025, places are limited.
Have you had an article accepted for publication recently?
The Australian Pain Society (APS) is keen to share publications from our members with their colleagues via our eNewsletter. If you’ve had an article accepted or published recently, please contact our Assistant Editor Joanne Harmon via the APS Secretariat (aps@apsoc.org.au) with the title, authors, and reference (i.e., journal, volume, and DOI) of your article and request the submission template. We would love it if you also supply a short commentary (300 words max) to give our readers the gist of the article.
Characterizing phenotypes and clinical and health utilization associations of young people with chronic pain: latent class analysis using the electronic Persistent Pain Outcomes
Collaboration database
Thank you to APS members Professor Helen Slater and A/Prof Susie Lord, with their colleagues, Dr Rob Waller and Professors Anne Smith and Andrew Briggs for sharing the following recent publication. The authors gratefully acknowledge the assistance of, and discussions with, Dr David Holloway, Dr Hilarie Tardif, and Sam Allingham, from the ePPOC team, Australian Health Services Research Institute, University of Wollongong, Australia.
Article first published online: July 9, 2024
Journal Reference: Slater H, Waller R, Briggs AM, Lord SM, Smith AJ. Characterizing phenotypes and clinical and health utilization associations of young people with chronic pain: latent class analysis using the electronic Persistent Pain Outcomes Collaboration database. Pain. 2025 Jan 1;166(1):67-86. doi: 10.1097/j. pain.0000000000003326. Epub 2024 Jul 9. PMID: 39688968; PMCID: PMC11647817.
DOI: 10.1097/j.pain.0000000000003326
Abstract
Objectives
Using the Australian electronic Persistent Pain Outcomes Collaboration (ePPOC), a binational pain registry collecting standardised clinical data from paediatric (PaedsePPOC) and adult pain services (AdultePPOC), we explored and characterised nationally-representative chronic pain phenotypes and associations with clinical and sociodemographic factors, health care utilisation and medicines use of young people.
Methods
Data from 68 adult and 12 paediatric pain services for a five-year period January 2018-December 2022 (first episode, including treatment information), were analysed. Young people ≥ 15 and < 25 years captured in
PaedsePPOC and AdultePPOC Australian data registry were included. Unsupervised latent class analysis (LCA) was applied to explore the existence of distinct pain phenotypes, with separate models for both services.
Results
A three-phenotype model was selected from both paediatric and adult ePPOC data, with 693 and 3,518 young people included respectively (at least one valid indicator variable). Indicator variables for paediatric models, were: pain severity, functional disability (quasisurrogate ‘pain interference’), pain count, pain duration, pain-related worry (quasi-surrogate ‘catastrophising’) and emotional functioning; and, for adult models: pain severity, pain interference, pain catastrophising, emotional functioning and pain self-efficacy. From both services, three similar phenotypes emerged (‘Low’, ‘Moderate’, ‘High’), characterised by an increasing symptomseverity gradient in multidimensional painrelated variables, showing meaningful differences across clinical and sociodemographic factors, health service utilisation and medicines use.
Conclusions
Derived phenotypes point to the need for novel care models that differentially respond to the needs of distinct groups of young people, providing timely, targeted, age-appropriate care. To effectively scale such care, digital technologies can be leveraged to augment phenotype-informed clinical care.
Declaration
HS, AMB and RW, were funded by the Australian Government Medical Research Future Fund (MRF2016567) with co-funding from the Government of Western Australia, Department of Health (WA Health), with support from Curtin University. The authors have no other conflicts to declare.
Developed by the Australian Pain Society in collaboration with the National Ageing Research Institute, this FREE ‘train-the-trainer’ pain management program is for use by sta in both residential aged care facilities and organisations that provide aged care in the community, as well as NDIS providers.
Bite-sized 10 minute training modules!
Eight (8) painACT modules: One for the trainer called “How to use the painACT trainer program”, and seven modules for the trainer to train their sta :
Introduction to pain in aged
Impact
Conversations
Source
Developed by the Australian Pain Society in collaboration with the National Ageing Research Institute, this FREE ‘train-the-trainer’ pain management program is for use by sta in both residential aged care facilities and organisations that provide aged care in the community, as well as NDIS providers.
For more information:
painACT is available on the Australian Pain Society website and consists of: > trainer learning module documents > short training video clips, and > participant handout material apsoc.org.au/painACT-Online-Learning
Major Healthcare Improvements Announced: Expanded Access and Affordable Treatments for Endometriosis
On behalf of peak body for endometriosis, the Australian Coalition for Endometriosis is pleased to support the announcement of the latest investment into Endometriosis and Persistent Pelvic Pain. The Australian Government has announced a major healthcare package in response to community feedback and sustained advocacy efforts by the Australian Coalition for Endometriosis (ACE) and our member organisations.
From March 1, 2025, commonly used contraceptive pills like Vaz® and Yasmin® will be listed on the Pharmaceutical Benefits Scheme (PBS), reducing annual costs from $380 to just $126 or $30 with a concession card.
Additionally, bulk billing and increased Medicare rebates will make longterm contraceptives like IUDs and implants more affordable, offering effective options for managing endometriosis, adenomyosis, and heavy bleeding.
A key part of the package is the addition of 11 new Endometriosis and Pelvic Pain Clinics, expanding the network to 33 clinics nationwide.
"This is a significant win," Jess Taylor said. "But our work doesn't stop here -we'll continue advocating for even more services and ongoing support."
About ACE:
ACE is the peak body representing people with endometriosis and pelvic pain in Australia, advocating for improved healthcare, support services, and community awareness. Through collaboration and sustained advocacy, ACE works to improve outcomes for those affected by these conditions.
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30 APR - 1 MAY 2025 | PRE-CONGRESS WORKSHOPS
NEW!
> Arthritis Training, Learning and up-Skilling (ATLAS) platform, an evidence-based eLearning program for health professionals promoting a person-centred approach to arthritis care, including arthritis pain care
Other items of interest for our members:
> Latest opioid data from the Australian Bureau of Statistics: Opioid induced deaths in Australia.
> Australia’s annual overdose report 2024 from the Pennington Institute
> Australian Atlas of Healthcare Variation Series: This series explores how healthcare use in Australia varies depending on where people live. It investigates reasons for variation that may be unwarranted, and provides specific achievable actions to reduce unwarranted variation
> ePPOC: electronic Persistent Pain Outcomes Collaboration: The electronic Persistent Pain Outcomes Collaboration (ePPOC) is an Australasian initiative that aims to improve the quality of care and outcomes for people who experience chronic pain.
> PainHEALTH: painHEALTH‘s aim is to help health consumers with musculoskeletal pain access reliable, evidence-based information and tips to assist in the co-management of musculoskeletal pain. painHEALTH is an initiative of the Department of Health, Western Australia
> Stanford University CHOIR: CHOIR Collaborative Health Outcomes Information Registry
> Opioid Podcasts for GPs: These podcasts are produced by David Outridge GP, and FAChAM Trainee as a project under the auspices of Dr Steven Kelly Staff Specialist in Addiction Medicine, Kullaroo Clinic Gosford. A weekly series from the Hunter Postgraduate Medical Institute (University of Newcastle)
> Airing Pain: Pain resources via an online radio show produced by Pain Concern, a UK registered Charity
> Indigenous Resources: Webpage on the APS website aggregating Indigenous resources
TGA
> Codeine information hub
NSW Agency for Clinical Innovation resources:
> Brainman and Pain Tool Kit translations
> Pain Management Resources
> Quicksteps to Manage Chronic Pain in Primary Care
> Built into Quicksteps: “How to de-prescribe and wean opioids in general practice”
> A list of helpful apps for consumers and clinicians
> Chronic Pain in the ED
Vale Dr Keith Chan, Canberra, ACT
By Dr Geoffrey Speldewinde
It is with deep sadness that we announce the passing of Dr. Keith Chan, a highly respected Specialist in Rehabilitation and Pain Medicine who made a lasting impact on Canberra and its surrounding communities. Keith moved to Canberra in 2007 with his young family, bringing with him extensive training from the United States, where he earned Board Certifications in both Rehabilitation and Pain Medicine, including specialised training in Interventional Pain Management. Each of these certifications were subsequently recognised in Australia. He provided an invaluable service as a Staff Specialist in Rehabilitation Medicine at The Canberra Hospital. He also played a big role in the transition of inpatient rehabilitation from The Canberra Hospital to the specially designed and built University of Canberra Hospital providing subacute care.
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Much of his private practice was in Pain Medicine where he excelled in patient-centred care with judicious use of medications and interventions in the context of educating and optimising a patient's self-management and self-care.
With his passing and his peace from his medical condition, we — his colleagues, staff, and the many patients whose lives he touched — strive to honour his legacy by upholding his ethos of good will, equanimity, great humour, ever-ready sage and calming advice, and easy-going view of the world. Our heartfelt condolences are shared with his wife Lynn, daughter Janine, and son Sean.
Vale, Keith Chan.
Annual General Meeting
The 2025 Australian Pain Society (APS) Annual General Meeting (AGM) will be held on Wednesday 19 March 2025 from 5:30 – 6:30pm AEDT, via Zoom.
A General Business Meeting (GBM) will immediately follow the AGM.
If you are unable to attend the AGM, your apology would be most appreciated.
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A formal Notice of the AGM along with the 2025 Agenda, Proxy form, Minutes from the 2024 AGM and GBM, and other documents has been distributed by separate email to all members.
Your RSVP by 5:30pm AEDT, Monday 17 March 2025 would be most appreciated.
APS Membership Renewals 2025
Renewal notices for 2025 have been sent by email to members, check your inbox!
Thank you for your continued support and membership of the APS.
Please note:
1. We understand that circumstances change, so each year we ask you to select your appropriate level of membership.
2. This system of self-reporting subscription levels was implemented in 2009 for the benefit and fairness of all members.
3. There has been a small increase applied to the 2025 membership fees.
Please refer to the rates below for your 2025 membership fee:
a. Regular A $130 (was $120)
b. Regular B $260 (was $230)
c. Regular C $440 (was $370)
d. Retired $65 Concessional Rate
e. Student $65 Concessional Rate
Before renewing, please ensure you review and update your member profile online.
Payments can be made by Credit Card or BPAY.
Did you know that the Australian Pain Society is a registered charity with ACNC? Your donation will help the Society to promote the prevention and control of diseases in human beings associated with pain.
All donations of $2 or more to APS are tax-deductible.
New Members as at 25 February 2025
Miss Rachel Almaw Musculoskeletal Medicine
Ms Elizabeth Andresen Nursing
Mr Bede Ashley Physiotherapy
Mrs Lisa Austin Pharmacy
Ms Bec Black Occupational Therapy
Ms Isabelle Bogard Physiotherapy
Miss Jess Coventry Physiotherapy
Ms Natasha Huong Dong Anaesthesia
Ms Marloes Duijzings Psychology
Dr Jennifer English Geriatrics
Mrs Erica Ferreira Physiotherapy
Mrs Melody Francis Physiotherapy
Miss Breeanna Gaylor Physiotherapy
Miss Romina Gollan Physiotherapy
Ms Amy Gowland Occupational Therapy
Mrs Rachael Gregory Nursing
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Mr Jackson Hart Science Research
Dr Romilly Hawter General Practice
Mr Campbell Hogan Physiotherapy
Dr Amity Honor Psychiatry
Mr Benjamin Hoy Science Research
Dr Andy Hsieh General Practice
Prof Mohammad Amjad Kamal Science Research
Dr Richard Lawrence Rheumatology
Miss Sally Lawton Physiotherapy
Mr Eric Le Pharmacology
Dr Kathleen Leach Psychology
Dr Ben Low Rehabilitation Medicine
Ms Katherine Ma Exercise Physiologist
Miss Brittany McCarthy Science Research
Dr Edmund Neo Rehabilitation Medicine
Mr Joseph Parmenter Pharmacy
Ms Marie Pham Physiotherapy
Dr David Phillips Anaesthesia
Ms Mia Ryan Exercise Physiologist
Ms Tracy Shand Psychology
Dr Clive Sun Pain Medicine Physician
Mrs Tracy Taulier Education
Dr Jemma Todd Psychology
Ms Maree Whyte Nursing
Mrs Kirsten Williams Physiotherapy
Dr Brad Williamson Pain Medicine Physician
Mr Jake Wilson Physiotherapy
Mrs Zoe ( Jianyun) Zhu Nursing
Miss Douer Zhu Pharmaceutical
Calendar of Events
20-22 March 2025
New Zealand Pain Society (NZPS)
NZPS25 - Weaving our Kete
Te Papa Tonogarewa, Wellington, NZ
4-6 April 2025
Spine Society of Australia
2025 Spine Society of Australia 36th Annual Scientific Meeting
Perth Convention & Exhibition Centre, Perth, WA
13-16 April 2025
Australian Pain Society (APS)
2025 Australian Pain Society 45th Annual Scientific Meeting
Pullman Melbourne Albert Park, Melbourne, VIC
24-26 April 2025
European Pain Federation - EFIC
EFIC 14th Congress - Comorbidity of chronic pain and mental health disorders: Breaking the cycle
Cite - Centre de Congres, Lyon, France
2 May 2025
Australian and New Zealand College of Anaesthetists & Faculty of Pain Medicine (ANZCA/FPM)
2025 FPM Symposium - Diving Deep
Pullman Cairns International Hotel, Cairns, QLD
2-4 May 2025
ASEAPS 2025 - 10th Association of South-East Asian Pain Societies Congress
From Pain to Empowerment
Singapore EXPO, Singapore
2-6 May 2025
Australian and New Zealand College of Anaesthetists (ANZCA)
ANZCA 2025 Annual Scientific MeetingFutureproof
Cairns Convention Centre, Cairns QLD
17-20 June 2025
International Association for the Study of Pain (IASP)
International Symposium on Paedriatric Pain (ISPP 2025)
Scottish Event Campus (SEC), Glasgow, Scotland
20-23 July 2025
Rehabilitation Medicine Society of Australia & New Zealand in conjunction with New Zealand Rehabilitation Association
RMSANZ NZRA 2025 8th Annual Scientific Meeting - Building Lives
Te Pae Christchurch Convention Centre, Christchurch, NZ
8-10 August 2025
Neuromodulation Society of Australia & New Zealand
NSANZ 2025 18th Annual Scientific Meeting
ICC Sydney, NSW
23-30 August 2025
Pain Revolution 2025
Rural Outreach and Cycling Tour
Various venues: Bundaberg, Hervey Bay, Gympie, Maleny, Noosa, Birtinya, Sunshine Coast, QLD
4-6 September 2025
International Association for the Study of Pain (IASP)
NeuPSIG 2025, 9th International Congress on Neuropathic Pain
Urania Berlin e.V., Berlin, Germany
17 October 2025
Pain Nurses Australia
2025 Annual Professional Day - Pain in Vulnerable Populations
Waterview in Bicentennial Park, Sydney
Olympic Park, Sydney, NSW
19-21 November 2025
Australian & New Zealand Spinal Cord Society
ANZCoS 2025: Rivers of Innovation
Brisbane Convention and Exhibition Centre, Brisbane, QLD
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Vision, Purpose & Priorities
Vision:
All people will have optimal pain management throughout life.
Purpose:
The Australian Pain Society is a multidisciplinary association whose purpose is to advance pain management through education, research, and advocacy for transformational improvements in clinical care.
Priorities:
In order to achieve our purpose, the Australian Pain Society will provide:
> Membership
> Research
> Education
> Services and resources
> Good governance and operations
> Advocacy
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Directors
President:
Mrs Joyce McSwan
Gold Coast Primary Health Network
Persistent Pain Program,
QLD and PainWISE
Tel: 0412 327 795 Fax: 07 3539 9801
President-Elect:
Ms Bernadette Smith
Psychology Plus
South Burnie TAS
Tel: 03 6431 9959 Fax: 03 6431 9950
Secretary:
Mrs Dinah Spratt
Physiotas Physiotherapy
Shearwater TAS 7307
Tel: 03 6428 7500 Fax: 03 6424 7811
Treasurer:
Dr Laura Prendergast
Pain Service, Northern Health
Broadmeadows VIC 3047
Tel: 03 8345 5166 Fax: N/A
Work days Mon & Thu
ACT Director:
Dr Andrew Watson
Calvary Hospital
Canberra ACT 2617
Tel: 02 6201 6352 Fax: N/A
NSW Director:
Dr Connor Gleadhill
Department of Health and Aged Care
Primary Care Division
Newcastle NSW 2038
Tel: 0405 203 661 Fax: N/A
NT Director:
Position Vacant
Tel: 02 9016 4343
QLD Director:
Dr Duncan Sanders
Pain Management Unit, Sydney Medical School, University of Sydney / Managing Pain Clinic and E3 Physio
Gold Coast QLD
Tel: 07 5620 1234 Fax: 07 3009 0420
SA Director:
Ms Heather Gray
Royal Adelaide Hospital
Adelaide SA 5000
Email: heather.gray@sa.gov.au
TAS Director:
Mr Sinan Tejani
Launceston General Hospital
Launceston TAS 7250
Tel: 0469 967 841 Fax: N/A
VIC Director:
Dr Esther Dube
Austin Health
Heidelberg VIC 3084
Email: referrals@periop.net.au
WA Director:
Ms Jacintha Bell
Lifeworks Occupational Therapy
Mount Lawley WA 6050
Tel: 0451 178 880 Fax: 08 6323 3329
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Office Bearers
Immediate Past President:
Ms Trudy Maunsell
Retired QLD
SPC Chair:
Professor Kevin Keay
Department of Anatomy
University of Sydney
Sydney NSW 2006
Tel: 02 9351 4132 Fax: 02 9351 2817
IASP Liaison:
Professor Fiona Blyth AM
Sydney School of Public Health
Faculty of Medicine and Health
University of Sydney
Camperdown NSW 2006
Email: Fiona.blyth@sydney.edu.au
Communications Coordinator:
Mrs Joyce McSwan
Gold Coast Primary Health Network
Persistent Pain Program, QLD and PainWISE
Tel: 0412 327 795 Fax: 07 3539 9801
Newsletter Editor:
Dr Lincoln Tracy
School of Public Health and Preventive Medicine
Monash University
Melbourne VIC 3004
Tel: 03 9903 0288
Newsletter Assistant Editor:
Dr Joanne Harmon
School of Clinical and Health Sciences
University of South Australia
Adelaide SA 5000
Tel: 08 8302 1442
Scholarship/Grant Selection
Subcommittee Co-Chairs:
Emeritus Professor Maree Smith AC
Centre for Integrated Preclinical Drug Development
University of Queensland St Lucia QLD 4072
Professor Luke Henderson
Anatomy & Histology, School of Medical Sciences
Brain & Mind Centre
University of Sydney
Camperdown NSW 2006
Secretariat:
DC Conference & Association
Management Pty Ltd
PO Box 637
North Sydney, NSW 2059
Tel: 02 9016 4343
Email: aps@apsoc.org.au
Website: apsoc.org.au