Biotecnika&Rasayanika
ModulesFor BioinformaticsGlobalToolsandTechniques(BGTI)–2.0
30-Days:Hands-onSummerInternshipwithCaseStudies
Session No.
UnitNo.andTopic
UNIT-1:Introduction:WhyLearnBioinformatics?
Day1 Ice-breakingSessiononBioinformaticsGlobalToolsandTechniques
Day2 Scope&OpportunitiesinBioinformatics:India&Abroad
Day3 UnderstandingKeyterminologyinBioinformaticsDatabases
UNIT-2:Dicepheringmoleculesatthesub-molecularlevel
Day4 CarbohydratesandProteins
Demoontools:Cheminformatics
Day5 LipidsandNucleicacids
Demoontools:ChemDraw&ChemSketch
UNIT-3:Bioanalytics:Understandingthepatternsoflife
Day6 PrimarySequences–DNA,RNA,andProteins
Demoontools:NCBI,EMBL,DDBJ,andSBI
Day7 SecondaryStructures–DNA,RNA,andProteins
Demoontools:GORV,Swissmodel,I-TASSER,Phyre2
Day8 TertiaryStructures–Stability,folding,andmisfolding
Demoontools:ProteinDataBank(PDB),EMBLandSBI
Day9 BiochemicalandMetabolicpathwayanalysis
Demoontools:KEGGdatabaseandCytoscape
UNIT-4:Biocomputing-Computer-AidedDrugDesign(CADD)
Day10 Introduction, Drug discovery pipeline: Target identification and validation, Lead identificationandoptimization,Virtualscreening
Demo: IMPPAT and Dr Duke's Phytochemical and Ethnobotanical databases for PhytochemistryResearch.
Day11 ADMETStudiesfortheleadoptimization.
Demoontools:SWISS-ADME,Analysis,andInterpretation;Boiled-EggModel
Day12 Introduction for Protein and Modelling concepts, Types, HomologyModelling, andAb-initioMethod.
Demoontools:PDBtools,SwissExPaSy
Day13 Moleculardocking:LigandoptimizationandTargetidentification
Demoontools:MolegroPackage
Day14 QSARStudiesandInterpretationofdocking
Demo on Molecular docking software: Patchdock, Autodock, ClusPro web server
DAY15 IntroductiontoMolecularDynamicsandSimulation(MDS).
Unit-5:Biomimetics:DrivingDeeper
DAY16 Pre-clinical (Bacterial,Fly,Plants,andMurinemodels),HumanClinicalTrialsfor drugdiscovery,FunctionalgenomicsandComparativegenomics.
Demoontool:Differentialexpressionanalysisonbacterialgenome.
DAY17 Protein-protein interaction network, STRING, Network terminology, Pathway enrichmentanalysis
Demoontool:STRINGandCytoscape.
DAY18 Human Genome project, Bacterial Genomics, Human Microbiome, and Epigenetics
Demoontool:MothurandQIIME
DAY19 Sanger sequencing, Next Generation Sequencing: DNA Sequencing, RNA Sequencing.miRNAAnalysis.
Demo on tool: Databases: dbSNP, Clinvar, Genome browsers: UCSC and Ensembl
Unit-6:PeningDown:PublishorPerish
DAY20 Publicationtypes,formats,andjournals
Demoontool:Elsevier,Springer,Wiley,MDPI,andBenthamSciences
DAY21 ResearchmadeeasywithArtificialIntelligence(AI&ML)
Demoontool:ApplicationsofChatGPTinBioResearch
DAY22 Selectionofthejournalandindexing
Demoontool:Journalfinder
DAY23 Submission,Revision,andre-submissionprocess
Demoontool:EditorialManager
Unit-7:ProposalWritingandGrantSubmission
DAY24 Structureandingredientsofproposalwriting
DAY25 Networkingandfundingfrom(govt./private/industrialpartners)
DAY26 Portalsforgrantsubmissionandprerequisites
DAY27 Generatingprimarydataforproposalandfunding
Unit-8:LaunchYourself
DAY28 Generatingideas,Start-ups,andBioenterpreunship
DAY29 Livetroubleshootingsession
DAY30 OpenDiscussion