MDA March-April 2014

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Apple’s Heart Rate Monitor IPad In Health And Medicine 'India's healthcare sector to grow to $158.2 bn in 2017'

Overview Indian Medical Industry 2014

Pharmacy Council of India

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e d i t o r i a l

highlights Medical Devices & Equipment | Healthcare | Pharmaceutical Journal Vol.6 No.2 |March-April 2014 | Annual Subscription: Rs.500

Managing Editor Sarvjit

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Joint Editors

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India’s Healthcare Sector

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The NeXt generation of LED lamps for operating room

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MEDICAL FAIR ASIA 2014

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Selecting An Electrologist for Treatment of Unwanted Hair

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Nanotechnology In Medicine

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Mahajan Imaging, Delhi gets India’s first Silent MRI

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The Top 30 Global Medical Device Companies

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Overview - Indian Medical Industry 2014

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Robots in medical research

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iPads In Health And Medicine

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Apple Receives Patent for Integrate Heart Rate Monitor

Electrophysiology Technology Allows Early Disease Diagnosis Researchers developed a small analyser that could be able to detect medical conditions by measuring the electrical behaviour of cells.

It may well be the minutia of biological cell properties, but the electrophysiological behaviour of our cells determines how effective the cells function, and indeed cellular survival. And the electrolyte balance in cells is often affected in disease conditions.

With this in mind, a group of biological engineers based at the University of Surrey in the UK have used electrophysiological principals to develop new technologies to determine the presence of pathophysiology within the cells. The team, led by Professor Michael Hughes, developed a small analyser, which is able to determine the difference between healthy and unhealthy cells by measuring their electrical behaviour. They hope that the device will be able to detect oral cancers and other diseases at an early stage or subclinical presentation.

The device, which has been named 3DEP (developed by DEPtech and distributed by Labtech), uses a technique known as dielectrophoresis.

The technique works on the basis that electrical properties of unhealthy cells differ from those of normal ones. The process involves the use of the reader which has been developed by the group, and an inexpensive

disposable ‘3-D Well Plate’ chip, which delivers the cell sample for analysis. The aim is to produce a cheap (less than £5), effective, accurate and quick diagnostic test that can be used across a wide range of disease states. The reader can deliver a result within approximately 10 seconds, according to the company.

The research group is currently working in association with the Eastman Dental Institute, the Royal Marsden and Bradford Royal Infirmary to conduct clinical trials to detect oral cancer, and also with

the University of California in order to identify stem cells that could be used to repair cellular damage to the brain. There are many common diseases that simply do not

currently have a cheap diagnostic test and the developers are hopeful that the 3DEP could be an effective and affordable answer to this problem. The well plates are available in a range of sizes making them flexible for a wide range of cell types and the technology has already been formally launched to the AES Electrophoresis Society and is commercially available.

Harnessing technology such as the 3DEP device, which uses well known techniques and the normal

physiological state of cells to benchmark against abnormal functions, seems simple in principa,l but highly complex in development. It will be interesting to see how the technology develops. v

Medical Device ASIA | March-April 2014 | 3

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