High Purity Andarine (S4) powder (401900-40-1) for bodybuilding

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High Purity Andarine (S4) powder (401900-40-1) for bodybuilding Overview Andarine powder is a non-steroidal selective androgen receptor modulator (SARM) that has tissue-selective androgenic and anabolic effects in animals. It improves muscle strength and prevents bone loss in orchidectomized rats. Like other SARMs, andarine produces anabolic effects in muscle and bone without androgenic effects.

Anabolic agents, including andarine and other SARMs, are prohibited by the World Anti-Doping Agency.

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Andarine (S4) powder (401900-40-1) video Andarine (S4) powder Base Information Name

Andarine (S4) powder

CAS

(401900-40-1)

Purity

98%

Chemical name

Andarine

Synonyms

(2S)-3-[4-(Acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3 -(trifluoromethyl)phenyl]propanamide;N-[4-Nitro-3-(trifluorometh yl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpr opanamide; S 4;

Molecular Formula

C19H18F3N3O6

Molecular Weight

441.36

Melting Point

147-149°C

InChI Key

YVXVTLGIDOACBJ-SFHVURJKSA-N

Form

Solid

Appearance

Light Yellow Solid

Half Life Solubility

Soluble in DMSO, not in water

Storage Condition

0 – 4 C for short term (days to weeks), or -20 C for long term (months).

Application

Andarine, also known as GTx-007 and S-4, is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting

Testing Document

Available

Andarine (S4) powder General Description Andarine powder, also known as GTx-007 and S-4, is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy. Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to 2/4

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finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.

Andarine (S4) powder (401900-40-1) History While steroidal SARMs have been around since the 1940s, a number of nonsteroidal SARMs that do not serve as substrates for CYP19 aromatase or 5Îą-reductase,Andarine is a selective androgen receptor modulator, or SARM. Pharmaceutical companies developed andarine for the treatment of osteoporosis and muscle wasting disease. The compound helps build stronger bones and muscle mass but is especially effective at decreasing body fat, providing body builders with “a cut look.â€?

Andarine(S4) (401900-40-1) Application Similar to other SARMs, Andarine has greater affinity to androgen receptors, the common site of action of male sex hormone- testosterone. While traditional synthetic steroids bind to androgen receptors indiscriminately, SARMs are very specific in its mode of action, affecting only the ones present in skeletal muscles and bones. Undoubtedly, this selectivity gives Andarine an edge over steroids. Some of the remarkable benefits of Andarine include increase in lean muscle mass, lipolysis and boosting of stamina and strength.

Andarine(S4) (401900-40-1) More research Andarine, commonly known as S4 in the market, comes under umbrella of wide group of drugs called SARM (Selective Androgen Receptor Modulator), but S4 is considered to be more potent and beneficial as compared to other similar SARMs like LGD-4033. It was first manufactured by GTX labs during its research aiming for treatments of senile- onset muscle wasting diseases like muscular dystrophy, osteoporosis and benign enlargement of prostrate.

It has shown promising results during animal trials and currently, numerous medical research teams are conducting various human trials to elicit more beneficial effects on skeletal muscle mass, strength and bone density. Even though S4 is yet to be prescribed by practitioners, it is widely included in body fitness regime of aspiring athletics. Moreover, the selectivity of the drug eliminates numerous side effects that traditional steroids bring.

Andarine(S4) (401900-40-1) Document Download 3/4

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COA

Andarine(S4) (401900-40-1) Reference 1: Cawley AT, Smart C, Greer C, Liu Lau M, Keledjian J. Detection of the selective androgen receptor modulator andarine (S-4) in a routine equine blood doping control sample. Drug Test Anal. 2015 Oct 12. doi: 10.1002/dta.1867. [Epub ahead of print] PubMed PMID: 26456227.

2: Girgis CM, Mokbel N, Digirolamo DJ. Therapies for musculoskeletal disease: can we treat two birds with one stone? Curr Osteoporos Rep. 2014 Jun;12(2):142-53. doi: 10.1007/s11914-014-0204-5. Review. PubMed PMID: 24633910; PubMed Central PMCID: PMC4083371.

3: de Rijke E, Essers ML, Rijk JC, Thevis M, Bovee TF, van Ginkel LA, Sterk SS. Selective androgen receptor modulators: in vitro and in vivo metabolism and analysis. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(9):1517-26. doi: 10.1080/19440049.2013.810346. Epub 2013 Jul 24. PubMed PMID: 23883284.

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