Buy Pure Nmn Bulk powder (1094-61-7) HPLC≥99%

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Buy Pure Nmn Bulk powder (1094-61-7) HPLC≼99% 01

Overview

Nicotinamide mononucleotide powder ("NMN", "NAMN", and "β-NMN") is a nucleotide derived from ribose and nicotinamide.Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH).

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beta-Nicotinamide mononucleotide powder video

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Nmn powder Base Information

Name

NMN powder

CAS

1094-61-7

Purity

98%

Chemical name

beta-Nicotinamide mononucleotide; nicotinamide mononucleotide; 1094-61-7; beta-NMN; nicotinamide ribonucleotide

Synonyms

3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl] pyridinium

Molecular Formula

C11H15N2O8P

Molecular Weight

334.221 g/mol

Melting Point

>96°C

InChI Key

DAYLJWODMCOQEW-TURQNECASA-N

Form

Solid

Appearance

white powder

Half Life

/

Solubility

soluble in water

Storage Condition

Hygroscopic, -20˚C Freezer, Under Inert Atmosphere

Application

Nicotinamide mononucleotide (“NMN”, “NAMN”, and “β-NMN”) is a nucleotide derived from ribose and nicotinamide.

Testing Document

Available

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Nmn powder General Description

beta-Nicotinamide mononucleotide powder (1094-61-7) is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice.

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It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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Nmn powder (1094-61-7) History

Beta-Nicotinamide mononucleotide (NMN) powder is an intermediate of NAD+ biosynthesis produced from nicotinamide through nicotinamide phosphoribosyltransferase (NAMPT) and also referred to as NMN or nicotinamide ribotide. In recent studies of NMN applications to prevention and diagnosis of age-dependent diseases such as diabetes, neurodegenerative disorder, cardiac disease etc., it has become one of hottest biomarkers on discussion for anti-aging, lately.

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Nmn powder Mechanism Of Action

beta-Nicotinamide mononucleotide (β-NMN) is a biosynthetic precursor of nicotinamide adenine dinucleotide (NAD+) known to promote cellular NAD+ production and counteract age-associated pathologies associated with a decline in tissue NAD+ levels.

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Nmn powder (1094-61-7) Application

Aging cells. Indeed, past work in Imai’s lab has shown that giving beta-Nicotinamide mononucleotide to older mice has beneficial effects on metabolism throughout the body, including positive effects in skeletal muscle, liver function, bone density, eye function, insulin sensitivity, immune function, body weight, and activity levels.

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Nmn powder (1094-61-7) More research

Aging cells. Indeed, past work in Imai’s lab has shown that giving beta-Nicotinamide mononucleotide to older mice has beneficial effects on metabolism throughout the body, including positive effects in skeletal muscle, liver function, bone density, eye function, insulin sensitivity, immune function, body weight, and activity levels.

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Nmn powder (1094-61-7) Document Download

COA

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Nmn powder (1094-61-7) Reference

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1, Bogan, KL; Brenner, C (2008). “Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition”. Annual Review of Nutrition. 28: 115–30. doi:10.1146/annurev.nutr.28.061807.155443. PMID 18429699.

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2, Brazill, JM; Li, C; Zhu, Y; Zhai, RG (June 2017). “NMNAT: It’s an NAD+ synthase… It’s a chaperone… It’s a neuroprotector”. Current Opinion in Genetics & Development. 44: 156–162. doi:10.1016/j.gde.2017.03.014. PMC 5515290. PMID 28445802.

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3, “Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice”. Cell Metabolism. 13 December 2016.

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4, Stipp, David (March 11, 2015). “Beyond Resveratrol: The Anti-Aging NAD Fad”.

Scientific American Blog Network.

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Everything You Need to Know About Nicotinamide Riboside Chloride Nicotinamide Mononucleotide(NMN): Benefits, Dosage, Supplement, Research

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PRECAUTION AND DISCLAIMER: This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

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