Buy Pinoline powder (20315-68-8) from Wisepowder

www.wisepowder.com

wise12@wisepowder.com

Buy Pinoline powder (20315-68-8) from Wisepowder Overview Pinoline powder is a methoxylated tryptoline (5-methoxytryptoline) long claimed to be produced in the pineal gland during the metabolism of melatonin, however its pineal occurrence remains controversial. Its IUPAC name is 6-methoxy-1,2,3,4-tetrahydro-β-carboline, usually abbreviated as 6-MeO-THBC, and its more common name is a combination of "pineal beta-carboline". The biological activity of this molecule is of interest as a potential free radical scavenger, also known as an antioxidant, and as a monoamine oxidase A inhibitor.

1/3

www.wisepowder.com

wise12@wisepowder.com

Pinoline powder (20315-68-8) video Pinoline powder (20315-68-8) Base Information Name

pinoline powder

CAS

20315-68-8

Purity

98%

Chemical name

6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole 20315-68-8 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Synonyms

6-methoxytryptoline 6-Methoxy-1,2,3,4-tetrahydro-beta-carboline pinoline

Molecular Formula

C12H14N2O

Molecular Weight

202.257 g/mol

Melting Point

216- 224 °C

InChI Key

QYMDEOQLJUUNOF-UHFFFAOYSA-N

Form

Solid

Appearance

/

Half Life

/

Solubility

/

Storage Condition

/

Application

Pinoline is a methoxylated tryptoline (5-methoxytryptoline) long claimed to be produced in the pineal gland during the metabolism of melatonin,

Testing Document

Available

Pinoline powder General Description Pinoline (6-methoxy-tetrahydro-beta-carboline) powder can be formed in the mammalian body under physiological conditions from 5-hydroxytryptamine or as a tricyclic metabolite of melatonin. Both melatonin and pinoline inhibited lipid peroxidation and showed comparable activity in a total antioxidant status test. These results support the importance of the indolic part of the molecule and 2/3

www.wisepowder.com

wise12@wisepowder.com

the 5-methoxy group common to both compounds in terms of the ability of these molecules to quench the hydroxyl radicals.

Pinoline powder (20315-68-8) History Pinoline (20315-68-8) Mechanism Of Action Pinoline (20315-68-8) Application Pinoline (20315-68-8) More research As pinoline has been shown to exert an antidepressant-like effect in behavioral experiments and has been reported to have a low toxicity, this compound should be further studied as a potential antidepressant with pronounced antioxidative effects.

These results further support the importance of pineal gland in antioxidative protection.

Pinoline (20315-68-8) Document Download COA

Pinoline (20315-68-8) Reference 1. Schiller, Erich; Bartsch, H. (2003). Free Radicals and Inhalation Pathology: Respiratory System, Mononuclear Phagocyte System, Hypoxia and Reoxygenation, Pneumoconioses, and Other Granulomatoses, Cancer (Google Books, page view). Springer. p. 107. ISBN 978-3-540-00201-7. Retrieved 2009-02-14.

2. Airaksinen, M. M., Huang, J. T., Ho, B. T., Taylor, D., and Walker, K. (1978). “The Uptake of 6-Methoxy-1,2,3,4-Tetrahydro-β-carboline and its Effect on 5-Hydroxytryptamine Uptake and Release in Blood Platelets”. Acta Pharmacol Toxicol. 43 (5): 375–380. doi:10.1111/j.1600-0773.1978.tb02281.x.

3. Bartels, S. P. (2006) U.S. Patent No. 20,060,292,202 Washington, DC: U.S. 4. { Mario de la Fuente et al. 2015 “Neurogenic Potential Assessment and Pharmacological Characterization of 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (Pinoline) and Melatonin–Pinoline Hybrids” http://pubs.acs.org/doi/abs/10.1021/acschemneuro.5b00041}

3/3