Best Price Pure Resveratrol powder (501-36-0) for Sale

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Best Price Pure Resveratrol powder (501-36-0) for Sale 01

Overview

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural compound found in red grape skin, Japanese knotweed (polygonum cuspidatum), peanuts, blueberries and some other berries. It is a powerful antioxidant produced by some plants to protect them against environmental stresses. Antioxidants neutralize free radicals, which are believed to be the cause of aging. Japanese knotweed is the plant source with the highest resveratrol content.

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Resveratrol powder (501-36-0) video

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Resveratrol powder Base Information

Name

Resveratrol

CAS

501-36-0

Purity

98%

Chemical name

Resveratrol

Synonyms

5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; trans-Resveratrol; (E)-5-(p-Hydroxystyryl)resorcinol; (E)-Resveratrol; trans-3,4′,5-Trihydroxystilbene;

Molecular Formula

C14H12O3

Molecular Weight

228.24

Melting Point

243-253°C (dec.)

InChI Key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

Form

Solid

Appearance

white powder with

Half Life

at studies, suggest a half life up to 1.6 hours

Solubility

Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (≥16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL).

Storage Condition

-20˚C Freezer

Application

Minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation.

Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor

powder

slight yellow cast

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initiation, promotion and progression.

Testing Document

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Available

Resveratrol General Description

Resveratrol is a naturally occurring antioxidant found in red grapes an berries.

Resveratrol powder is known to have a range of beneficial health and nootropic benefits. Resveratrol tends to be concentrated mostly in the skins and seeds of grapes and berries. These parts of the grape are included in the fermentation of red wine, hence its particularly high concentration of resveratrol.

However, much of the research on resveratrol has been done in animals and test tubes using high amounts of the compound.

Of the limited research in humans, most has focused on supplemental forms of the compound, in concentrations higher than those you could get through food.

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Resveratrol powder (501-36-0) History

The first mention of resveratrol was in a Japanese article in 1939 by Michio Takaoka, who isolated it from Veratrum album, variety grandiflorum, and later, in 1963, from the roots of Japanese knotweed.

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Resveratrol Mechanism Of Action

Resveratrol interferes with all three stages of carcinogenesis – initiation, promotion and progression. Experiments in cell cultures of varied types and isolated subcellular systems in vitro imply many mechanisms in the pharmacological activity of resveratrol. These mechanisms include modulation of the transcription factor NF-kB, inhibition of the cytochrome P450 isoenzyme CYP1A1 (although this may not be relevant to the CYP1A1-mediated bioactivation of the procarcinogen benzo(a)pyrene), alterations in androgenic actions and expression and activity of cyclooxygenase (COX) enzymes.

Resveratrol was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease. Again, this has not yet been tested in humans for any disease.

Research at the Northeastern Ohio Universities College of Medicine and Ohio State University indicates that resveratrol has direct inhibitory action on cardiac fibroblasts and may inhibit the progression of cardiac fibrosis.

Note that resveratrol bioavailability depends on its conjugate forms: glucuronate and sulfonate, despite that most in vitro studies use the aglycone form of resveratrol (‘aglycone’ means without a sugar molecule attached, as in the figure in this article).

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Resveratrol powder Application

Resveratrol can prevent the oxidation of low density lipoprotein, and has the potential effect on preventing cardiovascular disease, cancer, antivirus and immune regulation. Its main role is antioxidant properties.

Cardiovascular drugs. It can reduce hematic fat and prevent heart disease. It also has the effect on AIDS. Antioxidants and the activity in anti-inflammatory, antithrombotic, anti-cancer, anti-cancer, anti hyperlipidemia and antibacterial.

Anti-aging, regulating blood lipid, cardiovascular protection, anti-hepatitis.

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Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects.

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Resveratrol (501-36-0) More research

As a dietary supplement, take 250mg twice daily, or as directed by your medical professional. It is recommended that it be taken with meals in order to increase the body’s absorption. It is also best to take it with other grape extracts or with raw grapes, as this makes the effects of Resveratrol much more pronounced. A milligram scale is needed to accurately measure dosages.

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Resveratrol Document Download

COA

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Resveratrol powder (501-36-0) Reference ]Timmers S., Konings E., Bilet L, et al. Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans. Cell Metabolism 2011;14: 612-622 Powell, R.G., et al.: Phytochemistry, 35, 335 (1994), Jeandet, P., et al.: J. Phytopathol., 143, 135 (1995), Mattivi, F., et al.: J. Agric. Food Chem., 43, 1820 (1995) Leiro J, Arranz JA, Fraiz N, Sanmartín ML, Quezada E, Orallo F (2005). “Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling”. Int. Immunopharmacol. 5 (2): 393–

PRECAUTION AND DISCLAIMER:

PRECAUTION AND DISCLAIMER: This Material is Sold For Research Use Only. Terms of Sale Apply. Not for Human Consumption, nor Medical, Veterinary, or Household Uses.

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