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PAINMEDICINE ACASE-BASED LEARNINC SERIES

The Knee
STEVEN D. WALDMAN

Elsevier

1600JohnF.KennedyBlvd. Ste1800 Philadelphia,PA19103-2899

PAINMEDICINE:ACASE-BASEDLEARNINGSERIES THEKNEE

Copyright © 2022byElsevier,Inc.Allrightsreserved

ISBN:978-0-323-76258-8

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It’s Harder Than It Looks

MAKING THE CASE FOR CASE-BASED LEARNING

For sake of full disclosure, I was one of those guys. You know, the ones who wax poetic about how hard it is to teach our students how to do procedures. Let me tell you, teaching folks how to do epidurals on women in labor certainly takes its toll on the coronary arteries. It’ s true, I am amazing. . .I am great. . .I have nerves of steel. Yes, I could go on like this for hours. . .but you have heard it all before. But, it’ s again that time of year when our new students sit eagerly before us, full of hope and dreams. . .and that harsh reality comes slamming home. . .it is a lot harder to teach beginning medical students “doctoring” than it looks.

A few years ago, I was asked to teach first-year medical and physician assistant students how to take a history and perform a basic physical exam. In my mind I thought “this should be easy. . .no big deal” . I won ’t have to do much more than show up. After all, I was the guy who wrote that amazing book on physical diagnosis. After all, I had been teaching medical students, residents, and fellows how to do highly technical (and dangerous, I might add) interventional pain management procedures since right after the Civil War. Seriously, it was no big deal...I could do it in my sleep with one arm tied behind my back blah blah blah.

For those of you who have had the privilege of teaching “doctoring,” you already know what I am going to say next. It’s harder than it looks! Let me repeat this to disabuse any of you who, like me, didn’t get it the first time. It is harder than it looks! I only had to meet with my first-year medical and physician assistant students a couple of times to get it through my thick skull: It really is harder than it looks. In case you are wondering, the reason that our students look back at us with those blank, confused, bored, and ultimately dismissive looks is simple: They lack context. That’ s right, they lack the context to understand what we are talking about.

It’ s really that simple. . .or hard. . .depending on your point of view or stubbornness, as the case may be. To understand why context is king, you have to look only as far as something as basic as the Review of Systems. The Review of Systems is about as basic as it gets, yet why is it so perplexing to our students? Context. I guess it should come as no surprise to anyone that the student is completely lost when you talk about let’ s say the “constitutional” portion of the Review of Systems, without the context of what a specific constitutional finding, say a fever or chills, might mean to a patient who is suffering from the acute onset of headaches. If you tell the student that you need to ask about fever, chills, and the other “constitutional” stuff and you take it no further, you might as well be talking about the

InternationalSpaceStation.Justsaveyourbreath;itmakesabsolutelynosenseto yourstudents.Yes,theywanttoplease,sotheywillmemorizetheelementsofthe ReviewofSystems,butthatisaboutasfarasitgoes.Ontheotherhand,ifyoupresentthecaseofJannettePatton,a28-year-oldfirst-yearmedicalresidentwithafever andheadache,youcanseethelightsstarttocomeon.Bytheway,thisiswhat Jannettelookslike,andasyoucansee,Jannetteissickerthanadog.This,atitsmost basiclevel,iswhat Case-BasedLearning isallabout.

Iwouldliketotell youthat,smartguy thatIam,Iimmediatelysawthelight andbecameaconvert to Case-BasedLearning. Buttruthbetold,it wasCOVID-19that reallygotmethinkingabout Case-Based Learning.Beforethe COVID-19pandemic, Icouldjustdragthestudentsdowntothemed/surgwardsandwalkintoa patientroomandriff.Everyonewasawinner.Forthemostpart,thepatients lovedtoplayalongandthoughtitwascool.ThepatientandthebedsidewasallI neededtoprovidethecontextthatwasnecessarytoillustratewhatIwastrying toteach thewhyheadacheandfeverdon’tmixkindofstuff.HadCOVID-19 notrudelydisruptedmyabilitytoteachatthebedside,Isuspectthatyouwould notbereadingthis Preface,asIwouldnothavehadtowriteit.Withinaveryfew daysaftertheCOVID-19pandemichit,mydaysofbedsideteachingdisappeared,butmystudentsstillneededcontext.Thisgotmefocusedonhowto providethecontexttheyneeded.Theanswerwas,ofcourse, Case-BasedLearning. Whatstartedasadesiretoprovidecontext becauseitreallywas harderthanit looked ledmetobeginworkonthiseight-volume Case-BasedLearning textbookseries.Whatyouwillfindwithinthesevolumesareabunchoffun,real-life casesthathelpmakeeachpatientcomealiveforthestudent.Thesecasesprovide thecontextualteachingpointsthatmakeiteasyfortheteachertoexplainwhy, whenJannette’schiefcomplaintis, “MyheadiskillingmeandI’vegotafever,” itis abigdeal.

Havefun!

Spring2021

14 AnaliRojas A28-Year-OldYogaInstructorWithPain, Numbness,andaFootDrop188

15 MartinNash A21-Year-OldSprinterWithMedialCalfPainand Bruising204

Index 217

RoseWilliams A72-Year-OldFemaleWith RightKneePain

LEARNINGOBJECTIVES

• Learnthecommoncausesofkneepain.

• Developanunderstandingoftheuniqueanatomyofthekneejoint.

• Developanunderstandingofthecausesofarthritisoftheknee.

• Learntheclinicalpresentationofosteoarthritisoftheknee.

• Learnhowtousephysicalexaminationtoidentifypathologyofthekneejoint.

• Developanunderstandingofthetreatmentoptionsforosteoarthritisof thekneejoint.

• Learntheappropriatetestingoptionstohelpdiagnoseosteoarthritisof thekneejoint.

• Learntoidentifyredflagsinpatientswhopresentwithkneepain.

• Developanunderstandingoftheroleininterventionalpainmanagementinthe treatmentofkneepain.

122/74.Herhead,eyes,ears,nose,t hroat(HEENT)examwasnormal,as washercardiopulmonaryexamination.Herthyroidwasnormal.Her abdominalexaminationrevealedno abnormalmassororganomegaly. Therewasnocostovertebralangle(CVA)tenderness.Therewasnoperipheraledema.Herlowbackexaminationwasunremarkable.Ididarectal examandpelvic,whichwerebothnormal.Visualinspectionoftheknee revealednocutaneouslesionsorobviousherniaorotherabnormalmass. Theareaoverlyingtherightkneewaswarmtotouch.Palpationofthe rightkneerevealedmilddiffusetenderness,withnoobvioussynovitisor pointtenderness.Onballottementoftherightknee,therewasasuggestion ofmildeffusion.Therewasmildcre pitus,butIdidnotappreciateany poppingorcatching.Rangeofmotionwasdecreased,withpainexacerbatedwithactiveandpassiverangeofmotion.Theleftkneeexamination wasnormal,aswasexaminationofherothermajorjoints,otherthansome mildosteoarthritisinthefingers.Acarefulneurologicexaminationofthe upperandlowerextremitiesrevealedtherewasnoevidenceofperipheral orentrapmentneuropathy,andthedeeptendonreflexeswerenormal.

KeyClinicalPoints—What’sImportantandWhat’sNot

THEHISTORY

’ Nohistoryofacutekneetrauma

’ Nofeverorchills

’ Gradualonsetofrightkneepainoverthelastseveralweekswith exacerbationofpainwithkneeuse

’ Gratingsensationintherightknee

’ Sleepdisturbance

’ Difficultywalkingupstairsduetopain

’ Painonkneeling

THEPHYSICALEXAMINATION

’ Thepatientisafebrile

’ Normalvisualinspectionofknee

’ Palpationofrightkneerevealsdiffusetenderness

’ Nopointtenderness

’ Mildwarmthofrightknee

’ Crepitusandpainwithrangeofmotion

’ Noevidenceofinfection

’ Suggestionofamildeffusion

’ Noactivesynovitis

OTHERFINDINGSOFNOTE

’ NormalBP

’ NormalHEENTexamination

’ Normalcardiovascularexamination

’ Normalpulmonaryexamination

’ Normalabdominalexamination

’ Noperipheraledema

’ Nogroinmassoringuinalhernia

’ NoCVAtenderness

’ Normalpelvicexam

’ Normalrectalexam

’ Normalupperextremityneurologicexamination,motorandsensory examination

’ Examinationofjointsotherthantherightkneewerenormalotherthan somemildosteoarthritisofthehands

WhatTestsWouldYouLiketoOrder?

Thefollowingtestswereordered:

’ Plainradiographoftherightknee

TESTRESULTS

Theplainradiographsoftherightkneerevealedsignificantjointspacenarrowingandosteophyteformationconsistentwithsevereosteoarthritis(Fig.1.1).

CLINICALCORRELATION—PUTTINGITALLTOGETHER

Whatisthediagnosis?

’ Osteoarthritisoftherightkneejoint

TheScienceBehindtheDiagnosis

ANATOMYOFTHEKNEEJOINTS

Althoughbothcliniciansandlaypeoplethinkofthekneejointasasingle joint,fromtheviewpointofundersta ndingthefunctionalanatomy,itis morehelpfultothinkofthekneeastwose paratebutinterrelatedjoints:the femoral-tibialjointandthefemoral-patellarjoint( Fig.1.2 ).Thetwojoints shareacommonsynovialcavity,anddysfunctionofonejointcaneasily affectthefunctionoftheother.

Fig.1.1 Osteoarthritisoftheknee.AnteroposteriorstandingkneeX-raywithjointspaceloss,especiallyinthemedialcompartmentandosteophytesbilaterally.(FromVincentTL,WattFE.Osteoarthritis. Medicine.2018:46[3]:187 195[Fig.3C].)

Thefemoral-tibialjointismadeupofthearticulationofthefemurandthe tibia.Interposedbetweenthetwobonesaretwofibrocartilaginousstructures knownasthemedialandlateralmenisci(Fig.1.3).Themeniscihelptransmitthe forcesplacedonthefemuracrossthejointontothetibia.Themeniscihavethe propertyofplasticityinthattheyareabletochangetheirshapeinresponseto thevariableforcesplacedonthejointthroughitscomplexrangeofmotion.The medialandlateralmenisciarerelativelyavascularandreceivethebulkoftheir nourishmentfromthesynovialfluid,whichmeansthatthereislittlepotential forhealingwhentheseimportantstructuresaretraumatized.

Theprimaryfunctionofthefemoral-patellarjointistousethepatella,which isalargesesamoidboneembeddedinthequadricepstendon,toimprovethe mechanicaladvantageofthequadricepsmuscle.Themedialandlateralarticular surfacesofthesesamoidinterfacewiththearticulargrooveofthefemur (Fig.1.4).Inextension,onlythesuperiorpoleofthepatellaisincontactwiththe articularsurfaceofthefemur.Asthekneeflexes,thepatellaisdrawnsuperiorly intothetrochleargrooveofthefemur.

CLINICALPRESENTATIONOFARTHRITISOFTHEKNEEJOINT

Arthritisofthekneeisacommonpainful condition.Thekneejointissusceptibletothedevelopmentofarthritisfromavarietyofconditionsthathave theabilitytodamagethejointcartilage.Osteoarthritisisthemostcommon formofarthritisthatresultsinkneepain;rheumatoidarthritisand

Vastus medialis m

Vastus lateralis m

Iliotibial tract

Lat sup genicular a

Iliotibial tract

Popliteus t

Ant cruciate lig

Lat meniscus

Peroneus longus and extensor digitorum longus mm

Ant tibial recurrent a

Med sup genicular a

Adductor magnus t

Femur

Post cruciate lig

Med meniscus

Tibial collateral lig

Sartorius t

Tibia

Med inf genicular a

Gracilis and semitendinosus tt

Fig.1.3 Coronalviewoftheknee. a,artery; t,tendon; n,nerve; lig,ligament; m,muscle; tt,tendons. (FromKangHS,AhnJM,ResnickD. MRIoftheExtremities.Philadelphia:Saunders;2002:301.)

Thepainisconstantandischaracte rizedasachinginnature;itmay interferewithsleep.Somepatientscomplainofagratingorpoppingsensationwithuseofthejoint,andcrepitusmaybepresentonphysical examination.

Inadditiontopain,patientsoftenexperienceagradualreductioninfunctional abilitybecauseofdecreasingkneerangeofmotion,makingsimpleeveryday taskssuchaswalking,climbingstairs,andgettinginandoutofacarquitedifficult(Fig.1.5).Withcontinueddisuse,musclewastingmayoccur,andafrozen kneeduetoadhesivecapsulitismaydevelop.

Tibial n

Rectus femoris m

Prefemoral fat body

Quadriceps t

Suprapatellar bursa

Suprapatellar fat body

Patella

Transverse lig

Lat inf genicular a Infrapatellar fat body

Patellar lig

Tibia

Lat sup genicular a

Tibial n

Femur

Oblique popliteal lig and joint capsule

Ant cruciate lig

Post meniscofemoral lig of Wrisberg

Post cruciate lig

Gastrocnemius, lat head, and plantaris mm

Popliteal v and tibial n

Popliteus m

Soleus m

Fig.1.4 Sagittalviewoftheknee.(FromKangHS,AhnJM,ResnickD. MRIofthe Extremities.Philadelphia:Saunders;2002:341.)

TESTING

Plainradiographyisindicatedinall patientswhopresentwithkneepain (Fig.1.6).Basedonthepatient’sclinicalpresentation,additionaltestingmay bewarranted,includingacompletebloodcount,erythrocytesedimentation rate,andantinuclearantibodytesting.Magneticresonance(MRI)andultrasoundimagingofthekneeisindicated ifinternalderangement,aseptic necrosis,oranoccultmassortumoriss uspected,orifthediagnosisisin question( Figs.1.7 and 1.8).

Arthritis of the knee joint

Fig.1.5 Patientssufferingfromosteoarthritisofthekneeoftenexperienceagradualreductioninfunctionalabilitybecauseofdecreasingkneerangeofmotion,makingsimpleeverydaytaskssuchaswalking,climbingstairs,andgettinginandoutofacarquitedifficult.(FromWaldmanSD. Atlasof CommonPainSyndromes.4thed.Philadelphia:Elsevier;2019:Fig.105.1.)

Fig.1.6 X-raysofosteoarthritisoftheknee:(A)grade0normal,(B)grade1lateralfemoralosteophyte,(C)grade2lateralfemoralosteophyte,and(D)grade3lateralfemoralosteophyte.(From AltmanRD,GoldGE.Atlasofindividualradiographicfeaturesinosteoarthritis,revised. Osteoarthr Cart.2007:15[1]:A1 A56[Fig.22].)

Fig.1.8 Ultrasoundimageofthekneedemonstratingatornmedialmeniscus.(CourtesySteven Waldman,MD.)

TABLE1.1 ’ CausesofKneePainandDysfunction

Arthritis

• Osteoarthritis

• Rheumatoid

• Gout

• Pseudogout

• Reactivearthritis

• Septicarthritis

Trauma

• Fractures

• Meniscalinjuries

• Tendinitis

• Bursitis

• Ligamentousinjuries

MechanicalAbnormalities

• Jointmouse

• Alteredgaitduetohip,foot,orankleproblems

• Iliotibialbandsyndrome

• Patellarabnormalities(e.g.,patellaalta,bipartitepatella)

OtherCauses

• Avascularnecrosis

• Foreign-bodysynovitis

• Charcotjoint

• Neurofibromatosis

• Malignancy

• Pseudorheumatism

cyclooxygenase-2inhibitorsandphysicaltherapy.Thelocalapplicationofheat andcoldmayalsobebeneficial.Forpatientswhodonotrespondtothese treatmentmodalities,intraarticularinjectionoflocalanestheticandsteroidisa reasonablenextstep.

Forintraarticularinjectionoftheknee,thepatientisplacedinthesupinepositionwitharolledblanketunderneaththekneetogentlyflexthejoint.Theskin overlyingthemedialjointispreparedwithantisepticsolution.Asterilesyringe containing5mLof0.25%preservative-freebupivacaineand40mgmethylprednisoloneisattachedtoa1.5-inch,25-gaugeneedleusingstrictaseptictechnique. Thejointspaceisidentified,andtheclinicianplacesathumbonthelateralmarginofthepatellaandpushesitmedially.Atapointinthemiddleofthemedial edgeofthepatella,theneedleisinsertedbetweenthepatellaandthefemoral condyles.Theneedleisthencarefullyadvancedthroughtheskinandsubcutaneoustissuesthroughthejointcapsuleandintothejoint(Fig.1.9).Ifboneis encountered,theneedleiswithdrawnintothesubcutaneoustissuesandredirectedsuperiorly.Afterthejointspaceisentered,thecontentsofthesyringeare gentlyinjected.Thereshouldbelittleresistancetoinjection.Ifresistanceis encountered,theneedleisprobablyinaligamentortendonandshouldbe advancedslightlyintothejointspaceuntiltheinjectioncanproceedwithoutsignificantresistance.Theneedleisthenremoved,andasterilepressuredressing andicepackareappliedtotheinjectionsite.Clinicalstudiessuggestthat

Femur Patella
Inflamed and arthritic joint
Fig1.9 Intraarticularinjectionoftheknee.(FromWaldmanSD. AtlasofPainManagementInjection Techniques.4thed.StLouis:Elsevier;2017:Fig.132-4.)

viscosupplementationandtheinjectionofplatelet-richplasmamayalsoprovide symptomaticreliefofkneepainsecondarytoosteoarthritis.Theuseofultrasoundguidancemayimprovetheaccuracyofneedleplacementintotheintraarticularspace(Fig.1.10).

Physicalmodalities,includinglocalheatandgentlerangeofmotionexercises, shouldbeintroducedseveraldaysafterthepatientundergoesinjection. Vigorousexercisesshouldbeavoidedbecausetheywillexacerbatepatient symptoms.

HIGH-YIELDTAKEAWAYS

• Thepatientisafebrile,makinganacuteinfectiousetiology(e.g.,septicarthritis) unlikely.

• Thepatient’ssymptomatologyisnottheresultofacutetraumabutmorelikely theresultofrepetitivemicrotraumathathasdamagedthejointovertime.

• Thepatient’spainisdiffuseratherthanhighlylocalized,aswouldbethecase withapathologicprocesssuchasprepatellarbursitis.

• Thepatient’ssymptomsareunilateralandinvolveonlyonejoint,whichismore suggestiveofalocalprocessthanasystemicpolyarthropathy.

• Sleepdisturbanceiscommonandmustbeaddressedconcurrentlywiththe patient’spainsymptomatology.

• Plainradiographswillprovidehigh-yieldinformationregardingthebony contentsofthejoint,butultrasoundimagingandMRIwillbemoreuseful inidentifyingsofttissuepathology.

Fig.1.10 Ultrasound-guidedinjectionoftheknee.(CourtesyStevenWaldman,MD.)

BrendanBeckham

A32-Year-OldMaleWithAcute LeftMedialKneePainFollowing aSoccerInjury

LEARNINGOBJECTIVES

• Learnthecommoncausesofkneepain.

• Developanunderstandingoftheuniqueanatomyofthekneejoint.

• Developanunderstandingoftheanatomyofthemedialmeniscus.

• Understandthefunctionofthemusclesofthemedialmeniscus.

• Developanunderstandingofthecausesofmedialmeniscustear.

• Developanunderstandingofthevarioustypesofmedialmeniscusinjury.

• Learntheclinicalpresentationofmedialmeniscustear.

• Learnhowtoexaminetheknee.

• Learnhowtousephysicalexaminationtoidentifypathologyofthemedial meniscus.

• Developanunderstandingofthetreatmentoptionsformedialmeniscustear.

BrendanBeckham

“CallmeBrendan, ” mynew patientsaidasIintroducedmyself. Brendanwasa28-year-oldprofessionalsoccerplayerwithourlocal farmteamwiththechiefcomplaint of, “ Iblewoutmyrightknee.” Brendanstatedthataboutaweek ago,hewastakingtheballdown tothegoalandpivotedtoavoida defendertomoveinforthescore whenhefeltlike “something poppedinmyleftknee.Doc,itreallyhurt,butIwentaheadandmadethe kick,scored,andthenheadedofftothelockerroomtoicemyknee.Itook aquickshower,buttheinsideofmykneewaskillingme.Ididn ’timmediatelysayanythingtoanybodybecause,youknow,atmyage ... ” ashis voicedjusttrailedoff. “ButIfiguredwithice,Tylenol,andacoupleof daysoff,Iwouldberightasrain.ButhereIam, ” hesaidwithaweak smile.Iaskedifhehadeverhadanythinglikethisbeforeandheshookhis headandsaid, “ Justtheusualachesandpains.Inevermissagame.Ilove playingsoccer.Ihopetoplayforalongtimeyet,soIneedyoutogiveme ashotorsomething.Noharddrugs,becausetheleagueisalwaysdoing drugscreens. ”

ItoldBrendanIwoulddoallIcouldforhim,andthefirststepwasto figureoutexactlywhatwasgoingonwithhisknee.IaskedBrendanhowhewas sleepingandhesaid, “Prettywell,buteverytimeIrollontomyleftknee,Iwake up. ” Brendandeniedanyfeverorchills.

Onphysicalexamination,Brendanwas afebrile.Hisrespirationswere16 andhispulsewas64andregular.Hisbloodpressurewas118/82.Hishead, eyes,ears,nose,throat(HEENT)examwasnormal,aswashiscardiopulmonaryexamination.Histhyroidwasnormal.Hisabdominalexamination revealednoabnormalmassororgano megaly.TherewasaleftlowerquadrantscarthatBrendansaidwasfromanappendectomywhenhewasakid. Therewasnocostovertebralangle(CVA)tenderness.Therewasnoperipheraledema.Hislowbackexaminationw asunremarkable.Visualinspection oftheleftkneerevealedasmallareaofecchymosisoverthemedialjoint space.IaskedBrendanaboutitandhesaid, “Oh,that ’ snothing,justalittle bruisingfromtheacupuncture.” Iaskediftheacupuncturehelpedandhe gavemeawrysmileandsaidifitdid,hewouldbeatpracticeratherthan sittingonmyexamtable.

Fig.2.1 Elicitingthebulgesignforsmallkneejointeffusions.(FromWaldmanSD. PhysicalDiagnosis ofPain:AnAtlasofSignsandSymptoms.3rded.StLouis:Elsevier;2016:Fig.202-1.)

IaskedBrendantopointwithonefingertoshowmewhereithurtthe most,andhepointedtotheareaoverthemedialjointspace.Hesaid, “ Doc,itfeelslikeit ’ sdownintheknee;notontheoutside. ” Hevolunteered, “ Sometimesafterasquat,whenIgetup,itfeelslikemykneeis goingtocatchorlockup. ” Igentlyflexedandextendedthekneeandhe saidthatreproducedthepain.Theleftkneewasalittlewarmmediallybut didnotappeartobeinfected.IfeltlikeBrendanhadalargejointeffusion, soIperformedthebulgesigntestforkneejointeffusions,whichwaspositive,aswashisballottementtest( Figs.2.1 2.3).BrendanexhibitedapositiveMcMurraytestaswellasapositivesquattest( Figs.2.4 and 2.5).

Brendan ’ srightkneeexaminationwasnormal,aswasexaminationofhis othermajorjoints.Acarefulneurolo gicexaminationoftheupperandlower extremitiesrevealedtherewasnoevi denceofperipheralorentrapment neuropathy,andthedeeptendonreflexeswerenormal.ItoldBrendanI wasprettysureIknewwhatwasgoingonandweweregoingtogetsome teststoconfirmit.

Fig.2.4 TheMcMurraytestfortornmeniscus.(FromWaldmanSD. PhysicalDiagnosisofPain:An AtlasofSignsandSymptoms.3rded.StLouis:Elsevier;2016:Fig.219-1.)

KeyClinicalPoints

THEHISTORY

’ Ahistoryofsuddenonsetleftmedialjointpainfollowingasoccerinjury

’ Ahistoryofasuddenpopinthekneeatthetimeoftheacuteinjury

’ Ahistoryofcontinuedpaininspiteofconservativetherapy,including acupuncture

’ Nohistoryofprevioussignificantkneepain

’ Nofeverorchills

’ Sleepdisturbance

THEPHYSICALEXAMINATION

’ Thepatientisafebrile

’ Palpationofleftkneerevealstendernessoverthemedialjointspace

’ Aneffusionoftheleftkneejointasindicatedbyapositivebulgeand ballottementtest

Fig.2.5 Thesquattestfortornmeniscus.(A)Thesquattestformeniscaltear.Thepatientisasked firsttoperformafullsquatwiththefeetandlegsfullyexternallyrotated.(B)Thesquattestformeniscal tear.Thepatientisthenaskedtoperformafullsquatwiththefeetandlegsfullyinternallyrotated. (FromWaldmanSD. PhysicalDiagnosisofPain:AnAtlasofSignsandSymptoms.3rded.StLouis: Elsevier;2016[Figs.221-3and221-4].)

’ Thepresenceofmildecchymosisoverthemedialrightkneejointspace

’ Painonflexionandextensionoftheleftknee

’ ApositivedropMcMurraytest

’ Apositivesquattest

OTHERFINDINGSOFNOTE

’ NormalHEENTexamination

’ Normalcardiovascularexamination

’ Normalpulmonaryexamination

’ Normalabdominalexaminationwithawell-healedappendectomyscar noted

’ Noperipheraledema

’ Normalupperextremityneurologicexamination,motorandsensory examination

’ Examinationofotherjointswasnormal

WhatTestsWouldYouLiketoOrder?

Thefollowingtestswereordered:

’ Plainradiographsoftheleftknee

’ Magneticresonanceimaging(MRI)oftheleftknee

’ Ultrasoundoftheleftkneewithspecialattentiontothemedialmeniscus

TESTRESULTS

Theplainradiographsoftheleftkneerevealednoevidenceofbonyabnormality orfracture,butshowedpatellartiltingduetothelargeeffusionbehindand aroundthepatellartendon(Fig.2.6).TheMRIrevealedabuckethandletearof themedialmeniscus(Fig.2.7).Theultrasoundoftheleftmedialmeniscusreveals complextearingofthemeniscus(Fig.2.8).

ClinicalCorrelation—PuttingItAllTogether

Whatisthediagnosis?

’ Buckethandletearofthemedialmeniscus

TheScienceBehindtheDiagnosis ANATOMYOFTHEMEDIALMENISCUS

Themedialmeniscusisacrescent-shapedfibrocartilaginousbandthatspans themedialkneejoint(Fig.2.9).Thefunctionofthemedialmeniscusisto providechondroprotectionbyreducingpeakcontactforcesandfrictionbetween thefemurandproximaltibia(Fig.2.10).Themedialmensicusisattachedtothe tibiabythecoronaryligaments,whicharealsosubjecttotraumaticinjury (Fig.2.11).

Fig.2.7 Magneticresonanceimaging(MRI)revealsabuckethandletearofthemedialmeniscus.(A) TheparasagittalprotondensityMRIindicatesasmallmeniscus (whitearrows).(B)Thesagittalproton densityMRIthroughtheleveloftheintercondylarnotchshowsadisplacedbuckethandlefragmentof themedialmeniscus (brokenwhitearrows) lyinginferiorandanteriortotheposteriorcollateralligament.(C)Full-thicknesstearofthesupraspinatustendonaswellas(D)morechronictendinopathyof theinfraspinatustendonasevidencedbythickeningandhighsignalintensityofthetendon.(From WaldmanSD,CampbellRSD. ImagingofPain.Philadelphia:Saunders;2011:Fig.146.2A,B.)

section,whichisapproximately3.5cminlengthfromanteriortoposterior(see Fig.2.10).Itiswiderposteriorlyandisattachedtothetibiabythecoronaryligaments,whicharealsosusceptibletotrauma,asarethefibrousconnectionsfrom thejointcapsuleandmedialcollateralligament.

A B
C D

Fig.2.8 Longitudinalultrasoundimagerevealingcomplextearingofthemedialmeniscus.(Courtesy StevenWaldman,MD.)

Vastus lateralis m.

Lat. sup. genicular a.

medialis m.

Med. sup. genicular a.

Infrapatellar fat body

Iliotibial tract

Transverse lig.

Lat. meniscus, ant. horn

Iliotibial tract

Extensor digitorum longus m.

Med. meniscus, ant. horn

Sartorius, gracilis and semitendinosus tt.

Med. inf. genicular a.

Fig.2.9 Themedialmeniscusissubjecttodegenerativechangesaswellastearingsecondaryto acutetrauma. m,muscle; a,artery; ant,anterior; tt,tendons.(FromKangHS,AhnJM,ResnickD. MRIoftheExtremities:AnAnatomicAtlas.2nded.Philadelphia:Saunders;2002:305.)

Femur
Tibia
Vastus

Fig.2.10 Longitudinalultrasoundimagedemonstratingthetriangularmedialmeniscusnestled betweenthemedialbordersofthefemurandtibia.(CourtesyStevenWaldman,MD.)

Articular portion of femur

Medial portion of coronary ligament

Fig.2.11 Themedialmensicusisattachedtothetibiabythecoronaryligaments,whicharealsosubjecttotraumaticinjury,whichcanresultinmedialkneepain.(FromWaldmanSD. AtlasofUncommon PainSyndromes.3rded.Philadelphia:Saunders;2014:Fig.102-1.)

TABLE2.1 ’ FunctionsoftheMedialMeniscus

• Loadbearing

• Convertingthecompressiveforcestotensileforces

• Loaddistribution

• Stabilizationofthejoint

• Lubricationofthejoint

• Proprioception

Tibia

TABLE2.3 ’ MostCommonCausesofKneePain

LocalizedBonyor

JointSpace

Pathology

Fracture

Primarybonetumor

Primarysynovialtissuetumor

Jointinstability

Localizedarthritis

Osteophyte formation

Jointspaceinfection

Hemarthrosis

Villonodularsynovitis

Intraarticularforeign body

Osgood-Schlatter disease

Chronicdislocation ofthepatella

Patellofemoralpain syndrome

Patellaalta

Periarticular Pathology

Bursitis

Tendinitis

Adhesivecapsulitis

Jointinstability

Musclestrain

Musclesprain

Periarticularinfection notinvolving jointspace

Systemic Disease

Rheumatoid arthritis

Collagenvascular disease

Reitersyndrome

Gout

Othercrystal arthropathies

Charcotneuropathicarthritis

Sympathetically MediatedPain

Causalgia

Reflexsympathetic dystrophy

ReferredFrom OtherBody Areas

Lumbar plexopathy

Lumbar radiculopathy

Lumbar spondylosis

Fibromyalgia

Myofascialpain syndromes

Inguinalhernia

Entrapment neuropathies

Intrapelvictumors

Retroperitoneal tumors

FromWaldmanSD. PhysicalDiagnosisofPain:AnAtlasofSignsandSymptoms.3rded.StLouis: Elsevier;2016:Table201-1.

TESTING

PlainradiographsandMRIareindicat edinallpatientswhopresentwith kneepain,particularlyifinternalderangementoroccultmassortumoris suspected( Fig.2.13 ).Inaddition,MRIshouldbeperformedinallpatients withinjurytothemedialmeniscuswhofailtorespondtoconservative therapyorwhoexhibitjointinstabilityonclinicalexamination.Bonescan maybeusefultoidentifyoccultstressfracturesinvolvingthejoint,especiallyiftraumahasoccurred.Basedonthepatient ’ sclinicalpresentation, additionaltestingmaybewarranted ,includingacompletebloodcount, erythrocytesedimentationrate,an dantinuclearantibodytesting.

DIFFERENTIALDIAGNOSIS

Anyconditionaffectingthemedial compartmentofthekneejointmay mimicthepainofmedialmeniscaltear.Bursitis,arthritis,andentrapment neuropathiesmayalsoconfusethediagnosis,asmayprimarytumorsofthe kneeandspine.

Fig.2.13 (A C)Sagittalprotondensitymagneticresonanceimaging(MRI)demonstratingahorizontal tearofthemedialmeniscalbodywithananteriorhornfragmentdisplacedanteriortothemedialfemoralcondyle(A)andaposteriorhornfragmentdisplacedintotheintercondylarnotchadjacenttothe posteriorcruciateligament(B).BothdisplacedfragmentsweremissedonMRI.(C)Coronalshorttau inversionrecovery(STIR)MRIalsodemonstratingthedisplacedanteriorhornmeniscalfragmentmentionedin(A).Thisfragmentwaspalpabletothepatient,whobroughtittotheattentionofthesurgeon beforearthroscopy.(D,E)Arthroscopicimagesofthesamecasedemonstratingthehorizontaltearof themeniscalbodyandthedisplacedposteriorhorn(D)andanteriorhornfragments(E). (FromSampsonMJ,JacksonMP,MoranCJ,etal.ThreeteslaMRIforthediagnosisofmeniscaland anteriorcruciateligamentpathology:acomparisontoarthroscopicfindings. ClinRadiol.2008;63 [10]:1106 1111.)

TREATMENT

Initialtreatmentofthepainandfunctionaldisabilityassociatedwithinjuryto themedialcollateralligamentincludesacombinationofnonsteroidalantiinflammatorydrugsorcyclooxygenase-2inhibitorsandphysicaltherapy.Thelocal applicationofheatandcoldmayalsobebeneficial.Anyrepetitiveactivitythat exacerbatesthepatient’ssymptomsshouldbeavoided.Forpatientswhodonot respondtothesetreatmentmodalitiesanddonothavelesionsthatrequiresurgicalrepair,injectionwithlocalanestheticandsteroidisareasonablenextstep. Ultrasoundguidancewillincreasetheaccuracyofneedleplacement(Fig.2.14).

Physicalmodalities,includinglocalheatandgentlerangeofmotionexercises, shouldbeintroducedseveraldaysafterthepatientundergoesinjection. Vigorousexercisesshouldbeavoidedbecausetheywillexacerbatepatient symptoms.

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