April 9 2020

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VOLUME 138, ISSUE 22 | THURSDAY, APRIL 9, 2020

THEAGGIE.ORG

ONLINE INSTRUCTION PROVES PARAMOUNT FOR SLOWING SPREAD OF COVID-19, SCIENTISTS SAY Scientists call for campus closures due to novel coronavirus

Aggie Compass of the Basic Needs Center at the MU at UC Davis. (Photo by Timothy Li / Aggie)

THE PANTRY AND AGGIE COMPASS PARTNER TO CREATE WEEKLY GROCERY BAG PROGRAM FOR STUDENTS DURING COVID-19 PANDEMIC Students in need receive weekly, customizable grocery bags BY ALLY R USSELL campus@theaggie.org

The UC Davis campus is now empty as people shelter-in-place. (Photo by Justin Han / Aggie)

BY MA RG O ROSE N B AU M science@theaggie.org No longer are bikes dotting the streets of campus. No longer are lecture halls filling up with students diligently taking notes. No longer are dining halls bustling with freshmen. With the recent campus closures due to threats of spreading COVID-19, instruction is held remotely and entirely online this Spring Quarter. Students will be watching lectures, contributing to discussions and taking tests using computers in their homes, at their desks, at their dining room tables or even in their beds. UC Davis, along with all other UC campuses, made this decision based on guidance from local and state public health authorities, including the Centers for Disease Control and Prevention (CDC). Further measures, including stricter guidelines regarding avoidance of non-essential gatherings, have been implemented to ensure social distancing to keep the Davis community safe, said Cindy Schorzman, the medical director of Student Health and Counseling Services, via email. “The health and safety of students, faculty and staff is of paramount importance,” Schorzman said. Guidelines provided by the CDC as well as

local and state public health authorities informed UC Davis’ decision to transition all finals online at the end of last quarter and implement remote instruction for the entirety of Spring Quarter, Schorzman said. Because much is still unknown about this virus, these guidelines have been put in place, such as the CDC’s recommendation to reduce as much interaction with others as possible. “Online classes are the only way to properly practice social distancing while continuing school education,” said Angela Haczku, a professor of medicine and the associate dean for research at the UC Davis School of Medicine, via email. Currently, scientists believe that the virus spreads through respiratory droplets, which are produced when an infected person coughs or sneezes, Schorzman said. These droplets can land in the mouths or noses of others within six feet, which can then possibly be inhaled into the lungs. Individuals may also become infected by touching a surface or object that has the virus on it and then touching their faces, especially near the mouth or nose. “[The virus] stays on surfaces for days waiting for people to touch and pick them up,” Haczku said. “The virus first enters the mouth and gets into the gut system (sometimes causes diarrhea) and then makes its way into the airways, where it infects the lung.” Researchers have found that the symptoms

can vary widely. Some people may develop no symptoms, while others have a mild flu-like illness or even extremely severe pneumonia that can be fatal, Haczku said. Since the main way COVID-19 spreads is thought to be through inhaling respiratory droplets, the main strategies implemented to prevent its spread involve limiting potential exposure to these droplets, Haczku said. One strategy is social distancing since respiratory droplets are unlikely to travel more than six feet. Also, washing one’s hands multiple times a day to remove infected particles before they spread to others is very important. Lastly, cleaning and disinfecting frequently touched surfaces is effective to reduce the number of infected particles to which individuals are exposed, Haczku said. “[The virus] is spread by droplets and by contact, so if we limit the number of contacts people have, we can limit the spread of this infection,” said Dean Blumberg, the chief of pediatric infectious diseases at UC Davis Children’s Hospital. “We know it is already in the community, so we are trying to limit the number of contacts to limit the number in the entire community.”

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UC DAVIS RESEARCHERS WORK TOWARD DEVELOPING POTENTIAL VACCINE FOR COVID-19 Broad distribution of viable vaccine could take up to a year TE SSA KO G A / AG G I E

MIC HE L L E WON G science@theaggie.org As the lives of people around the world have drastically changed due to the novel coronavirus, or COVID-19, pandemic, researchers from UC Davis have been working tirelessly to understand the mechanisms of the severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2), the virus which causes the COVID-19 disease, in order to develop a potential vaccine. “Vaccines are based upon harnessing the ability of the immune system to recognize pathogens that they have counteracted before,” said Angela Haczku, a professor of medicine and associate dean for research at the UC Davis Medical School. “This feature or characteristic of the immune system is utilized when a small amount of the properties of the pathogen is being injected into the person.” When an individual is exposed to a virus, a particle from the virus is recognized by a component of the immune system called a T lymphocyte, explained Haczku. Once T lymphocytes come into contact with these particles, they be-

come memory T cells, which allow the immune system to recognize the virus if exposed to it again. Memory T cells allow helper lymphocytes to trigger B lymphocytes to produce the antibodies necessary to eliminate the viral particles. The amount of time these memory T cells can live on in a person’s body depends on the nature of the antigen, otherwise known as a foreign substance or toxin. When vaccines are administered, with a specific antigen, one no longer has to worry about contracting a certain disease in the future as memory T cells remember how to fight it off. But certain viruses, such as influenza, are able to mutate and become infectious again, so new vaccines must be created in response. The ability to develop a vaccine for COVID-19 depends on the nature of the virus and whether researchers will be able to find a proper antigen that T lymphocytes will be able to remember as the virus ages. “We don’t know what’s happening with [COVID-19] because humankind never encountered a coronavirus pandemic before,” Haczku said. “This is the very first time and therefore we never had the need to develop vaccines against coronavirus.” Although COVID-19 is novel, as the virus

which causes it is not the same as the viruses that cause other coronaviruses, previous research already conducted on other coronaviruses has contributed to some of the early progress for UC Davis researchers, according to Denis Hartigan-O’Connor, an associate professor in the department of medical microbiology and immunology and a core scientist at the California National Primate Research Center (CNPRC). “We learned from [previous research] about basically how to grow this virus, what things might inhibit it, what are some vaccine strategies that could be tried and then we start to think about the biology of this new agent and whether these strategies are applicable,” Hartigan-O’Connor said. Hartigan-O’Connor is a part of a group of researchers at the CNPRC working toward developing the first animal model in learning how SARS-CoV-2 affects monkeys. Smita S. Iyer, an assistant professor and core scientist at the infectious disease unit at the CNPRC, explained that once an animal model is developed, researchers will be able to answer fundamental questions that are difficult to answer with a human model. For example, factors like the mode of infection and viral concentration in the body, both of which are difficult to control for in humans, can be accounted for in these essential animal models. “We are not going to win the race to make a vaccine in academia because of resources,” Iyer said. “We just cannot compete with biotech [companies] and pharmaceutical [companies]. But what we can do and what we do really well is to understand the immune mechanism of protection, and so if we use that kind of approach to design a vaccine, that might inform the field.” Hartigan-O’Connor explained that his group plans to test a vaccine on monkeys in the next three to four months. Once they establish a candidate in which the vaccine seems to be effective, researchers will be able to quickly move onto human trials, Hartigan-O’Connor predicts. Iyer speculates that it will take another 12 months or, optimistically, closer to the end of the year for a viable COVID-19 vaccine for humans to be widely distributed .

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The Aggie Compass Basic Needs Center and The Pantry are teaming up to help provide students with basic needs despite constraints of the county and statewide shelter-in-place order and social distancing. Both spaces are currently closed in accordance with the county’s shelterin-place order, but both teams remain dedicated to providing assistance and resources to students virtually and in new, innovative ways. The evolving COVID-19 pandemic has simultaneously increased students’ need for basic needs and restricted the abilities of programs like Aggie Compass and The Pantry to meet these needs. Homelessness and food insecurity are prevalent issues among college students across the country. Around 250,000 students experienced homelessness in California in 2018, according to the U.S. Interagency Council on Homelessness. And more than 6.5 million Americans were forced to file for unemployment last week, according to The Guardian. At UC Davis, with nonessential services shutting down, many students have found themselves with reduced hours or out of work entirely. Before the COVID-19 pandemic, The Pantry provided around 800 UC Davis students with food products every day. To combat food insecurity during the pandemic, The Pantry and the Aggie Compass Basic Needs Center have partnered to create a weekly grocery bag program for students. While both The Pantry and Aggie Compass’ physical locations have closed, many services provided by both centers remain available online. Every week, 150 students can sign up by Sunday night to receive a pre-filled grocery bag on Thursday between 12:00 p.m. and 2:00 p.m. Instead of receiving food products in the MU, students can pick up their groceries on the Quad where pre-filled bags are spaced six feet apart from one another. On April 2, Aggie Compass and The Pantry provided 240 grocery bags filled with a week’s worth of groceries to students, nearly 100 more than they originally anticipated. “Students will have the option to choose between a meat bag, a vegetarian bag or both,” said Ryan Choi, the director of The Pantry. In addition to providing access to food products, Choi spoke at length about The Pantry’s goal of providing for students’ needs that may differ based on cultural or religious belief. Providing vegetarian options for students is one way Choi hopes to respect the diversity of students’ backgrounds and needs. After picking up their bag of groceries, students can check out with student volunteers from The Pantry and Aggie Compass, tabling nearby on the South Quad. In addition to groceries, students have the option to receive menstrual products in weekly grocery bags. PERIOD, a campus club, usually provides menstrual products in bathrooms across campus. The club is also adapting to the new constraints and demands created by COVID-19. Sabina Kabra, a fourth-year genetics and genomics major, is the operations and donations director for PERIOD. “During the coronavirus pandemic, more and more people are facing uncertainty surrounding health, shelter, employment, food and other necessities,” Kabra said. “PERIOD is trying to alleviate some of this uncertainty by providing free menstrual products. Menstrual products are a necessity and periods don’t stop during an epidemic.” PERIOD has donated over 3,000 menstrual products, according to Choi. Usually, The Pantry relies on both donations and their partnership with the Yolo County Food Bank to provide products for students. Due to the COVID-19 epidemic, the Yolo County Food Bank has become inundated with increased community demand for food. As a result, The Pantry is in need of community support and monetary donations now more than ever, according to Choi.

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