The CRS Group - CRS Pharma Solutions

MODULAR & CLIMATE CONTROLLED STORAGE SOLUTIONS www.crspharmasolutions.com

2 CRS Pharma Solutions provide fully validated Pharmaceutical temperature controlled storage

Our Solutions

Our expert team will work with you to customise our Pharma Grade storage solutions to your exact specifications for hire or purchase.

We offer

• Bespoke modular temperature controlled stores (built to fit within existing facility).

• Varying sizes of mobile climate stores to any required specification.

• Full range of temperature controlled storage solutions including Pharmagrade Cold Stores, ICH Stability Chambers, Combined Cold Stores, PCM/Blast Freezers, ULT Trolley Stores, and Incubators.

• Full in-house project management team with Prince 2 Verification.

• Engineering team chartered with both Engineers Ireland and IMechE.

• FGAS registered refrigeration engineers.

• Qualified electricians & fabricators.

• Experience managing logistics throughout the world.

• Construction experience with ability to assist with BCAR, PSDP/PSCS and certified emergency lighting.

• Pharmaceutical knowledge including GDP/GMP and can support IOPQ’s.

• In-house ability to CE certify products.

• Experience and knowledge of ATEX regulations.

• ISO 9001 accredited.

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Our Products

Products in our Pharmagrade range are fully CE marked and comply with all relevant Safety Health and Welfare at Work regulations.

They are also supplied complete with clearly written procedures for checking the functionality and compliance of the unit and for the safe operation, maintenance, and cleaning of the chamber.

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Pharmagrade Temperature Controlled Store

Standard features

• Our temperature controlled stores are weatherproof, pest/rodent proof and can be safely sited externally to free up valuable internal space.

• Our units are modular in construction and ensure fast on-site installation.

• Temperature range -40°C to +60°C with full air thermal mapping results available.

• Duty standby redundancy systems provide a back-up on all critical features.

• Recording and alarm probes are completely independent of control probes.

• All control and monitoring probes have an accuarcy of at least +/-0.5°C.

• Forced air circulation systems are used to ensure temperature uniformity.

• Auto-defrost interlock systems ensure the temperature within the chamber is not affected during defrost cycles.

• Internal lighting including emergency lights with minimum 500 lux lighting capacity.

• Local alarm systems cover temperature change, system faults, power failures,

in touch for flexible hire options!

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ICH Stability Chamber

ICH Stability Chambers are designed to cover the requirements for stability storage testing and are suitable to store samples at standard and low ICH conditions.

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Temp. +20°C to +40°C RH:+35% to +80%

• Active Pharmaceutical Ingredients (API) and the packaging do not deteriorate over time when exposed to external climatic conditions.

• Shelving options available to suit a variety of storage requirements.

• Tight temperature and humidity control to meet the ICH requirements.

• High/low temperature and humidity alarms.

• Safety features include person-trapped alarms, emergency lighting, non-slip flooring and door access control system.

• Remote user interface package, temperature and relative humidity alarms.

• Temperature range +20°C to +40°C, with temperature tolerance +/-2°C, and 35%-80% humidity range with +/-5% humidity tolerance.

• Optional backup power supply will provide power to the ACE Board and SmartPad in the event of power failure.

• Internal refrigerant leak detection system available.

• Low power consumption at 7.05 kWh!

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Stability storage testing is an essential part of the drug development process where samples and finished products are placed in specific environmental conditions.

www.crspharmasolutions.com

+2°C to +8°C Chilled Stores

Perfect for protecting the integrity of refrigerated temperature-sensitive products.

• Two refrigeration plant systems operate on a daily alternating duty standby cycle, to provide and maintain a chamber temperature of +5°C/-3°C for the storage of pharmaceutical product.

• Duty standby temperature control is arranged so that the main coolling unit defrosts naturally during the standby rest period while cooling is provided by the standby unit.

• If a high temperature alarm occurs, both duty and standby cooling units are activated until the temperature returns within the required range.

Pharmagrade

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• Dual close control modulating cooling systems ensure that temperature fluctuations are minimised.

• Early warning alerts at +3°C and +7°C.

• Internal lighting including emergency lights with minimum 500 lux lighting capacity.

• High-quality build specification with easy open doors and non-slip floors.

• Easy clean, stainless steel interiors.

• Local audio-visual alarms for total piece of mind.

• Energy efficient refrigeration units.

Whatever your requirements are, the CRS technical team will work with you to find a solution.

Call us on: 1890 929 824

+2°C to +8°C

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Pharmagrade Blast Freezers and Chillers

Boost the fluidity of your distribution chain with one of our pharmagrade blast freezers or chillers.

To -70°C

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• Large volumes of cold packs/plates can be frozen or chilled quickly.

• High velocity forced air cooling units.

• The need for slow conditioning in a conventional cooler is eliminated.

• Specialised low-temperature interior lighting for safety and convenience.

• Entirely weatherproof and designed for external use.

• Person-trapped emergency stop alarms for operator safety.

• Local audio-visual alarms for total peace of mind.

• High-quality build specifications with easy open doors and non-slip floors.

• Easy clean, stainless steel interiors.

• Easy to open heated lowtemperature doors.

• Wire grid racks and blast freezing trolleys available on request!

Cooling or conditioning time for phase change and eutectic materials will be cut drastically, extending their capacity for reuse. Ideal for the fast cooling of packs and plates intended for use in the shipping of frozen, refrigerated or controlled ambient products.

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Hot Box and Incubator Stores

Heat up and store your high temperature products in a controlled environment with the CRS Hot Box stores.

The consistent warm temperature is achieved by using a forced air circulation system with electric element heaters discharging up to 40 kW of heated air into the insulated chamber.

We can guarantee first use of brand new equipment!

• Local audio-visual alarms for total piece of mind.

• High-quality build specifications with easy open doors and non-slip floors.

• Easy clean, stainless steel interiors.

Up to +60°C

Flexible hire options available!

Flexible hire periods with competitive prices!

New and refurbished equipment available!

In-house engineering team and manufacturing! All installed components are CE marked and fully compliant with ISO 12100 standard!

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Pharmagrade

CRS Incubator Stores are built with reliability and safety in mind, incorporating precise heating and cooling control, and providing excellent temperature uniformity throughout the chambers.

• Close temperature control range from +5°C to +60°C.

• Uniform temperature +/- 1.5°C.

• Modulating cooling system.

• Entirely weatherproof and designed for external use.

• High-quality build specification with easy open doors and non-slip floors.

• Easy clean, stainless steel interiors.

• Person-trapped emergency alarms for safety.

• Digital air temperature controllers with alarms in the event of variation.

+5°C to +60°C

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Pharmagrade Mega Climate Controlled Stores & Crossdocking

Increase the efficiency of your stock turnaround and expand your storage capacities with our Mega Climate Controlled range and Crossdocking solutions.

• Store from 18-400 pallets!

• Temperature range from -40°C to +45°C.

• Humidity control options available.

• Entirely weatherproof and designed for external use.

• Fully customisable to meet your precise storage requirements.

CRS will help ensure that you meet all of your quality and regulatory requirements, providing full installation, Operation and Performance Qualification (IQ, OQ, & PQ), including empty and full state thermal mapping studies on all products!