Spatial configurations of networks are also being increasingly used to preliminarily assess potential movements of vehicles and pedestrians. This methodology, born approximately thirty years ago in the UK, is arguing that route choice is strongly affected by the configuration of the space and by the way the different parts of complex system are related to each other, according to the same rules that are applied to mathematical graph theories. This research is aimed to test to extent to which this is true for the Metropolitan area of Milan, comparing Space Syntax output with our macroscopic traffic model.