SABRİ ÜLKER PHYSIOLOGY LAB
IMPACT OF IN VIVO MODELING “If anything has changed over the years, now more than ever, we do not just focus on cell-based work or animal physiology, but rather we strive to present a complete story from the cellular level to whole-body physiology.” Karen E. Inouye, PhD
The partnership between Dr. Hotamışlıgil and Dr. Inouye goes back more than ten years, prior to her joining the lab in 2010. Dr. Hotamışlıgil was her academic advisor during a postdoctoral fellowship at Novartis Institutes for Biomedical Research. After completing her fellowship Dr. Inouye spent some time working in industry and focused on in vivo animal studies. In reflecting on her career path, Dr. Inouye noted, “It didn’t turn out to be what I was looking for in a career, and so I began the search for a new position. I was interested in getting back into research and using my skills in metabolic physiology. After some time looking for positions, I came across an ad for the position in the Hotamışlıgil Lab. Gökhan was looking for someone to run the department’s metabolic physiology core, which included using high-end metabolic physiology equipment, mouse imaging systems, and performing advanced in vivo techniques, such as glucose clamp studies in mice, in which I had extensive experience. I felt this position was a perfect fit for my skills and research interests, and was excited at the prospect of working in a lab that was at the forefront of metabolism research.” The Sabri Ülker Physiology Lab has a full complement of state-of-the-art small animal physiology instrumentation that Dr. Inouye uses to support the research of the members of the Center, in addition to colleagues throughout the Longwood Medical area.
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