Volume 7 | Issue 2
Inside This Issue
Charles D. Fraser Awarded 2024 Presidential Citation* See pg. 10
INDEX Oncology Research......... pg.3 Mental Health...................... pg.5 Healthy Heart....................... pg.6 Hospital News ..................... pg.8
February Edition 2024
Recent Federal Price Transparency Requirements for Hospitals and Plans
David A. King, J.D. Rachel M. Roberson, J.D. Polsinelli, PC
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he Center for Medicare and Medicaid Services (“CMS”) recently implemented certain price transparency requirements for hospitals and health plans through various regulations, Executive Orders, and the federal No Surprises Act. CMS reasons that these requirements help Americans know the cost of an item or service (including covered items / services) before receiving it, and that this information will make it easier for consumers to shop and compare prices. We have not yet seen much data indicating transparency has impacted consumer behavior. Each hospital must disclose on a publicly available website current standard charges for a) all items or services, the a) gross charges, b) discounted cash price, and c) payer-specific negotiated charge in a machine-readable format, and for a subset of 300 “shoppable” services, the current standard charges in a consumer-friendly list. These shoppable services are composed of 70 CMS-specified services and 230 hospital-selected services. Many hospitals have chosen to satisfy this shoppable services requirement by providing an online price estimator tool.
Likewise, plans and issuers must disclose on a publicly available website the costs of all items and services for in-network providers and the allowed amounts for, and billed charges from, all out-of-network providers in a
At least 14 hospitals have been assessed civil monetary penalties. And, while we are aware of activity by researchers to use the data provided by plans and issuers, to date, we are unaware of any audit or enforcement measures by any governmental agency against plans or issuers. Enforcement against plans and issuers may be complicated by the complexity of state insurance regulators and diversity of federal agency that oversee various types of health insurance coverage. Additionally, the recently implemented federal No Surprises Act (“NSA”), effective January 1, 2022, imposes some lesser-known price transparency requirements on an individual patient-by-patient basis. These requirements apply to all provider types and regardless of whether the items / services are in- or-network. For uninsured (self-pay) patients, providers must furnish a good faith estimates (“GFE”) to the patient within a very
As of January 2024, plans and issuers are required to expand the price estimator to all items and services.
Melanoma Overdiagnosis Soars Among White Americans, Study Finds See pg. 11
machine readable format, and an online price comparison tool (also available by phone, or in paper form, upon request) allowing an individual to receive an estimate of their cost-sharing responsibility for a 500 designate item or service from a specific provider. As of January 2024, plans and issuers are required to expand the price estimator to all items and services. CMS has been reviewing hospital websites and evaluation complaints made by members of the public and sent out over 1000 general warning letters or requests for corrective action plans (“CAPs”).
see Transparency ...page 14
PERMIT# NO PERMIT 11491 AUSTIN TXTX HOUSTON PRSRT STD US POSTAGE PAID
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JOMO: The Joy of Missing Out FOMO (fear of missing out) is very real in today’s always-on world. We constantly check for the next email, to-do or news headline. But this can leave us more stressed than ever.
Disconnecting is a fantastic way to recharge.
Replace FOMO with JOMO Use the “do not disturb” setting to focus
Wait to check after-hours emails
Only check the news headlines once a day
Enjoy a disconnected weekend
Just a few benefits of JOMO Deeper connections Better sleep
Less anxiety More creativity
© Copyright 2021 American Heart Association, Inc., a 501(c)(3) not-for-profit. All rights reserved. Unauthorized use prohibited. DS17941 10/21
February 2024
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Oncology Research Guarding Your Heart During and After Cancer Treatment By Karen Cohen, M.D., as emerging technologies and solutions. Texas Oncology– How Cancer Treatments Affect the Austin Central and Heart Round Rock
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long with remarkable advancements in life-saving cancer care, medical researchers also are making major progress in mitigating the potential impact some cancer treatment can have on the heart. While the vast majority of cancer patients will not develop treatment-related heart problems, it is important for patients and survivors to maintain heart-healthy habits as heart disease is the leading cause of death in the U.S. To help patients make informed decisions, a wealth of information is available about cardiac risks associated with certain cancer treatments, as well
In some patients, cancer treatments can present challenges to the heart’s health, including damage to the heart muscle, leading to short- and long-term cardiovascular complications. According to a study published in the European Heart Journal, cancer patients have a higher risk of dying from heart disease and stroke than cancer, with 10% of cancer patients dying from cardiovascular problems. Some chemotherapy drugs may disrupt the heart’s normal function, affecting its ability to pump blood efficiently, leading to chemotherapy-induced cardiotoxicity (CIC). Cardiotoxicity can lead to heart problems including cardiomyopathy, heart attack, heart failure, arrhythmia, or fluid buildup around the heart. Radiation therapy, vital in treating certain cancers, especially
those in the chest area, can also affect the heart and its surrounding structures. Radiation-induced heart disease (RIHD), can lead to coronary artery disease, valve problems, or pericardial diseases. While targeted therapies and immunotherapies aim for precision in attacking cancer cells, some may still have unintended effects on the heart. These treatments can interfere with the heart’s electrical system or weaken the heart muscle, resulting in myocarditis (an inflammation in the heart), arrhythmias, or heart failure. How Innovation is Protecting Heart
Health The ongoing research and integration of innovative cardioprotective strategies offer hope in preserving heart health. As these approaches evolve, the goal remains to provide effective cancer treatment while prioritizing the long-term cardiac well-being of patients. 1. Cardioprotective Medications: These medications aim to shield the heart from potential damage caused by chemotherapy agents without compromising the efficacy of cancer therapy. see Oncology ...page 14
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Ring in the New Year With a Goal-Oriented Mindset Setting Health-Related Resolutions for 2024 Is a Simple Way to Start By Chad Scott M.D., Family Medicine
resistance training, yoga, walking, biking, dancing, and body weight, resistance band, or light dumbbell exercises. According to the or many older Americans, a new Centers for Disease Control and year often starts with resolutions Prevention (CDC), regular physical that can lead to improvements in daily activity is vital for healthy aging. habits and better health. Disclaimer: Talk with your doctor In fact, according to a 2020 before significantly increasing your study, older adults who engaged activity level. This is especially in healthy lifestyle choices such important for those with underlying as physical activity, not smoking, medical conditions. Ask about the not drinking heavily, following the amounts and types of activities Mediterranean-style diet, and taking that may be best for you. part in mentally stimulating activities, had a 60% lower risk of developing 2. Eat healthfully. Prioritize healthy eating and snacking. Potential Alzheimer’s disease. benefits of healthy eating include As you consider changes and living longer, strengthening bones, goals for 2024, here are five achievable and lowering the risk of heart resolutions that may help you start the disease, Type 2 diabetes, and some new year on the right foot. cancers. Depending on how they 1. Pursue an active lifestyle. are prepared, home-cooked meals Staying active is an important may have lower levels of sodium, goal. Adults can engage in activity sugar, and fat when compared to at home including aerobic activity,
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meals at a restaurant. If you have allergies or conditions that require a special diet, talk to your doctor about your meal plan. 3. Challenge your brain and stimulate your mind. Because aging can cause changes to brain size, vasculature, and cognition, according to the National Institute of Aging, it’s important to keep your mind active. Living healthfully, both physically and mentally, may be one of the best defenses against the changes of an aging brain. Completing crossword
puzzles or playing games, such as chess, or enjoying a new hobby may be fun ways to keep your mind active. Talk to your doctor if you are worried about changes in your memory and thinking. They can help determine if those changes are normal or something more serious. 4. Stay connected with friends and family. The National Institute on Aging says older adults with strong social and community ties are more likely to live a longer life and cites research stating that isolation can see New Year ...page 12
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Mental Health UTSW Expert: Resilience Strategies Can Help Avert Holiday Blues By Eric Storch, Ph.D
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onsidering therapy is a big step, and finding the best therapist for your needs is important to form a connection. A Baylor College of Medicine psychologist provides a path for finding a therapist. “T he field of psycholog y, psychiatry and psychotherapy has advanced over the years, and one of the ways it has advanced is by learning that certain therapies may work best for certain problems,” said Dr. Eric Storch, professor and vice chair of psychology in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor. You should feel a sense of connection and comfort in disclosing things that are personal when speaking with a therapist. While opening up might be difficult, being able to do so comfortably is an initial good sign that you have found a good therapist.
At the first meeting, your therapist will ask questions about your situation, which will help them to conceptualize the problem while linking the best treatment option for that problem. The treatment plan should align with the therapies that have proved to work for that issue. “Not every therapist is equipped to treat every problem. This is comparable to physicians. You wouldn’t see a cardiologist for a problem with your lungs, you would see a pulmonologist,” Storch said. “In psychotherapy, you want to be looking for people who have a particular expertise in a particular type of problem.” Experts who treat OCD and anxiety like Storch often use cognitive behavioral therapy as it proves to be highly effective for facing fears. People exploring interpersonal dynamics might find a therapist with a different skillset. The therapist should discuss these treatment elements and discuss
evidence that supports doing a certain type of treatment. Storch recommends looking into patient advocacy groups that provide sets of questions you might ask a therapist during the initial meeting. Some common initial questions include, “What is your treatment approach?” “What is the evidence that supports that approach for my presenting problem?” “How long will it take?” or “What are some of the techniques or components we do in treatment?” “You can match up the answers with a trusted, vetted source to understand if this is the right treatment approach,” he said.
The relationship with your therapist should be a collaborative one with open discussion about the treatment approach, components and evidence supporting it. Finding a specialist can sometimes require a few tries until you find the right one. “If you see someone and it just isn’t the right connection or they don’t specialize in the established treatment for your problem, it’s ok to move on. It’s all about finding the right fit that allows you to best actualize yourself,” Storch said.
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Healthy Heart 11 Things to Know To Save A Life With CPR
FEEL GOOD AGAIN
By American Heart Association
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hen a heart stops, seconds matter. But too often, when someone has a cardiac arrest away from a hospital, people in a position to help don’t. Misunderstandings about CPR can keep people from acting. That costs lives. We asked experts to help clear things up. You can’t wait. If you see a teen or adult suddenly collapse, call 911 and don’t wait for professional rescuers, said Dr. Jose Cabañas, chief medical officer for Wake County, North Carolina. Each minute that CPR is delayed decreases the odds of survival by about 10%, research has shown. But having
Bee Gees’ “Stayin’ Alive.” You can also have someone search Google for “metronome” and enter “110.”) You don’t need certification. Training is great, and refresher courses are important, said Dr. Elizabeth Hunt, a professor of pediatric critical care medicine at Johns Hopkins University School of Medicine in Baltimore. But you “absolutely” do not have to have a card to perform CPR. “I advocate getting training,” said Hunt, who helped write a 2022 AHA scientific statement on lay responders and CPR. “But it is not necessary to save a life.” Don’t waste time checking for a pulse. If you see someone collapse, Hunt said, shake the patient gently and
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a bystander perform CPR doubles or triples the chances of somebody surviving, said Cabañas, who helped write the American Heart Association’s 2020 CPR guidelines. The steps for responding to a cardiac arrest, according to the AHA, are: − Check for responsiveness. − Call 911 or, if other people are on hand, have a second bystander make the call. 911 operators can guide rescuers through CPR. − Begin CPR while a second bystander retrieves an automated external defibrillator, or AED, if one is nearby. Do not stop CPR to go look for an AED. To perform CPR, place the heel of one hand in the center of the chest. Place the other hand on top and interlock the fingers. Push straight down hard and fast at 100 to 120 beats a minute. (That’s the rhythm of the
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ask, “Are you OK?” If they are not breathing or are breathing with “agonal breaths,” when breathing is abnormal or it appears the person is gasping for air, start CPR. People used to be told to check for a pulse. “But lay providers don’t need to do that,” Hunt said. Find the spot in the middle of the chest – “essentially, between the nipples” – and start pressing hard and fast. Don’t be squeamish. Roughly 350,000 U.S. adults experience an out-of-hospital cardiac arrest annually in the United States, according to AHA statistics. But bystanders, or lay rescuers, administer CPR in only about 40% of cases. Research shows people in low-income and predominantly Black neighborhoods are less likely to see Healthy Heart ...page 12
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CME content from Texas experts. Topics that impact your practice.
Join 250,000+ professionals who get free Continuing Medical Education (CME) with Texas Health Steps Online Provider Education. Choose from over 50 CME courses developed by trusted Texas experts, for experts like you. Quick courses and case studies on topics such as Medicaid guidelines, ethics and mental health, and more are all available 24/7.
Learn more at TXHealthSteps.com Content on the Texas Health Steps Online Provider Education website has been accredited by the Texas Medical Association, American Nurses Credentialing Center, National Commission for Health Education Credentialing, Texas State Board of Social Worker Examiners, Accreditation Council for Pharmacy Education, and UTHSCSA Dental School Office of Continuing Dental Education. Continuing Education for multiple disciplines will be provided for some online content.
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Hospital News UT Southwestern Molecular Geneticist Wins Hill Prize from TAMEST Russell Debose-Boyd, Ph.D., to Continue Cholesterol-Related Research with New Award from The Texas Academy of Medicine, Engineering, Science And Technology
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ussell DeBose-Boyd, Ph.D., Professor of Molecular Genetics at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research into a key
mechanism necessary for cholesterol control. The Hill Prize is a new award from TAMEST designed to accelerate high-risk, high-reward research ideas in Texas with significant potential for real-world impact. Funded by Lyda Hill Philanthropies, Hill Prizes are
awarded in five categories – Medicine, Engineering, Biological Sciences, Physical Sciences, and Technology – providing $500,000 to each recipient as seed funding to advance groundbreaking science and highlight Texas as a premier destination for world-class research. The prizes were announced Feb. 5 on the opening day of the TAMEST 2024
Annual Conference: Artificial Intelligence and Machine Learning at the AT&T Hotel and Conference Center in Austin. “It’s an honor to be recognized by Lyda Hill Philanthropies and TAMEST with this elite group of see Hospital News...page 13
MD Anderson Designated IAEA Collaborating Centre to Focus on Improving Radiation, Radiology And Nuclear Medicine Worldwide MD Anderson Is First U.S. Health Care Institution to Receive Distinction
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he University of Texas MD Anderson Cancer Center today announced the signing of an agreement with the International Atomic Energy Agency (IAEA) to become an IAEA Collaborating Centre. Working together, MD Anderson and the IAEA aim to enhance radiation oncology, radiation physics, radiology, nuclear medicine and nutrition globally. MD Anderson operates the most comprehensive radiation oncology facility in the world and will be the first IAEA Collaborating Centre in the United States focused on health care. “Our years of work with the IAEA and now being named a Collaborating Centre, exemplifies our commitment to advancing global efforts in cancer research, treatment and education,” said Peter WT Pisters, M.D., president of MD Anderson. “This collaboration underscores
February 2024
our dedication to fostering international collaborations that accelerate progress, particularly in low- and middle-income countries, where radiation treatment and diagnostic imaging capabilities are least accessible.” The IAEA has six decades of experience helping countries take action against cancer, and also cooperates with the World Health Organization (WHO) and other agencies within the United Nations system. An IAEA Collaborating Centre is an IAEA Member State institution that focuses on research, development and training and which has been designated by the IAEA to support its programmatic activities by implementing an agreed work plan. As of January 2024, 71 active IAEA Collaborating Centres worldwide operate in various areas related to the safe, secure and peaceful application of nuclear science and technology.
Chris McKee, Senior Vice President, Strategy and Business Development, MD Anderson and Rafael Mariano Grossi, IAEA Director General.
“Through its work, MD Anderson has demonstrated its firm commitment to advancing cancer patient care, research, education and prevention. With the signing of this agreement, and the designation of MD Anderson as an IAEA Collaborating Centre, we will support cancer care for all through training and educational activities in low- and middle-income countries under the IAEA’s Rays of Hope. By doing this, we are tackling cancer challenges where assistance is needed most,” said IAEA Director General Rafael Mariano Grossi at the signing ceremony in Vienna on January 30, 2024.
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MD Anderson’s designation as an IAEA Collaborating Centre follows several years of collaboration. The Imaging and Radiation Oncology Core (IROC) Houston in the Department of Radiation Physics at MD Anderson has provided several international Member States of the IAEA with quality assurance services, including audits, training and research. Additionally, training and expert missions have been conducted by teams from Radiation Physics, Radiation Oncology, Imaging Physics, Diagnostic Imaging and others. MD Anderson experts also have contributed to see MD Anderson ...page 13
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Charles D. Fraser Awarded 2024 Presidential Citation
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harles D. Fraser Jr., M.D., is one of four members of The University of Texas at Austin community to receive this year’s Presidential Citation from President Jay Hartzell. The award recognizes the extraordinary contributions of individuals who personify the University’s commitment to the task of transforming lives. Fraser has led a distinguished career as a world-renowned pediatric heart surgeon. In 2018, he joined Dell Medical School to establish the Texas Center for Pediatric and Congenital Heart Disease and the Institute for Cardiovascular Health, both in partnership with Ascension Seton. Under his leadership, both programs have transformed care for hearts in Central Texas and made rapid strides toward making Austin a premier destination for world-class cardiovascular care, from performing the first pediatric heart transplant
February 2024
at Dell Children’s Medical Center to recruiting a dozen preeminent surgical faculty to help lead the adult cardiovascular program. Fraser, who earned a bachelor’s degree with honors in mathematics from the University, is Charles D. Fraser Jr., M.D joined by Jim Breyer, an entrepreneurial investor and UT advisory board society forward. Collectively, they member; alumna Cloteal Davis save and improve lives and create Haynes, president of UT’s Precursors transformative opportunities that alumni group; and alumnus Dade will allow young men and women Phelan, speaker of the Texas House to flourish and positively impact of Representatives, as this year’s our world for generations to come,” honorees. Hartzell said. “Each person has “These honorees epitomize the reached incredible heights in their incredible talent that is responsible fields, generously shared their vast for moving our University and personal and professional insights,
and their involvement has encouraged other people of similar achievement and character to take part in what we are doing. I could not be more grateful for their talents, their kindness and their generosity.”
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Melanoma Overdiagnosis Soars Among White Americans, Study Finds About 83,000 Patients Overdiagnosed in 2018 Alone, Say Researchers
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ore than half of all melanoma diagnoses among white Americans may be overdiagnosed, according to a new study led by a researcher at Dell Medical School at the University of Texas at Austin. “Cases of cutaneous melanoma have risen significantly in the U.S. over the last 40 years, without an equivalent rise in mortality— which points to overdiagnosis,” said Ade Adamson, M.D., M.P.P., lead author of the study and an assistant professor in the Department of Internal Medicine at Dell Med. “Overdiagnosis happens when a melanoma is diagnosed that is actually harmless. That means the patient may undergo expensive, unnecessary treatments that may do far more harm than good,” said Adamson.
The research, published today in the journal BMJ Evidence-Based Medicine, found that an estimated 49.7% of melanomas diagnosed in white men and 64.6% in white women were overdiagnosed in 2018—a total of about 83,000 cases. Using national data from 1975 to 2018, researchers also found that the lifetime risk of being overdiagnosed with melanoma increased over the years. A large proportion of overdiagnosed melanomas are in the earliest stage (Stage 0 – also known as melanoma in situ). The authors estimate that 89% of melanoma in situ are overdiagnosed in white men and 85% in white women in the U.S. “This study shouldn’t dissuade people from getting concerning moles evaluated for melanoma,
especially if you are high risk,” said Adamson. “However, my hope is that it informs how people receive a melanoma diagnosis and brings
awareness to the phenomenon of overdiagnosis as an unintended consequence of screening.”
Age Well, Live Well HHS Highlights World Cancer Day By Stephanie Taylor, HHSC ASC Researcher
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orld Cancer Day on Feb. 4 is recognized worldwide to raise awareness and encourage the prevention, detection and treatment of cancer.
The Paris Charter established World Cancer Day in 2000 to promote research for cures and prevention, improve patient services and mobilize the global community against cancer. One of every five deaths in the U.S. is due to cancer, making it the second-leading cause of death, exceeded only by heart
disease. According to the Texas Cancer Registry (TCR), 99,642 adults ages 50 and older were diagnosed with cancer in 2020. This is a decrease from the 108,726 adults in that age group who were diagnosed in 2019. Among those older adults diagnosed with cancer in 2020, 46,433 were female and 53,209
were male. In 2020, the top five most common cancer areas in the body for adults ages 50 or older in Texas were the breast, prostate, lung and bronchus, colon and rectum, and kidney and renal pelvis, according to the TCR. “Age is the most important risk factor for cancer,” said Ramona Magid, chief prevention officer with the Cancer Prevention and Research Institute of Texas. “Healthy lifestyle choices can possibly reduce the chances of getting cancer. Higher risk lifestyle choices include smoking, alcohol consumption, physical
see Age Well, Live Well...page 14
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New Year Continued from page 4 contribute to high blood pressure. Even a virtual visit is better than no visit at all if a face-to-face visit isn’t possible. 5. Nurture an interest. People who engage in activities or hobbies may feel happier and healthier, according to the National Institute
on Aging. Learning new skills may also help increase cognitive function. Music, theater, dance, and creative writing are just some ways that older adults may be able to help improve their well-being through hobbies. These specific interests may help with memory,
boost self-esteem, reduce stress and increase social interactions. 6. See your doctor. While New Year’s resolutions such as watching what we eat or starting a fitness routine are common, prioritizing and scheduling a wellness visit with a primary care physician is
an important first step. Having regular checkups and preventive screenings, that are separate from visits due to illness, injury, or routine care for ongoing medical conditions, may help catch health problems early, helping you live a healthier and longer life.
If you’re wary of breathing into a stranger, don’t, Cabañas said. These days, training emphasizes hands-only CPR for the first few minutes, which has been shown to be as effective as conventional CPR with rescue breaths in the first few minutes after cardiac arrest in adults and teens. Mouth-to-mouth resuscitation – two rescue breaths after every 30 compressions – is important, however, for infants and children and if someone’s heart stopped because of choking or drowning, Hunt said. “But if you don’t
know how to do it, compressions-only is still great,” she said. Don’t worry about hurting someone. One of the biggest misconceptions about CPR, Cabañas said, is that you can harm someone in cardiac arrest. “The biggest risk is not doing something,” he said. Whether it’s concerns about legality, propriety or breaking bones, “I would emphasize that there is actually more potential harm by not doing or participating in providing bystander CPR when somebody collapses in front of you.” Good Samaritan laws protect people who step in to provide lifesaving care. Hunt puts it this way: If someone’s heart has stopped, “they’re already dead.” So any problems caused by CPR are not as bad as not doing CPR. Don’t be afraid to move them. If someone falls in a twisted position, you might have to straighten them out to get them on their back, Hunt said. If they are on a bed or couch, it is best to lower them to the ground so that CPR can be performed on a firm surface. You’re likely to use it on someone you know. Some people think they’ll never need to use CPR, Cabañas said. They’ll say, “My family’s healthy,” or they think it’s unlikely they’ll encounter anybody who needs help. “And that is not the case.” Research shows more than 70% of cardiac arrests happen in a home or private residence. So learning CPR should be part of any family’s safety plans, Cabañas said. Learning can be simple. Taking a CPR course will help people know how to respond, Cabañas said.
“There’s multiple ways to learn CPR these days,” he said. You can learn the basics from a free AHA video and get hands-on training through a community center or fire department. (Some airports and medical centers have hands-only training kiosks.) You’re qualified to use an AED. AEDs can shock a heart back into rhythm but, as with CPR, need to be used quickly. You should scout out where to find one in places you frequent. If a place you visit lacks one, Cabañas recommended talking with the manager. If you acquire one for your own facility, register it with the local EMS system so that 911 dispatchers know where to direct people. Some AEDs might say they are for trained personnel only. Ignore that, Hunt said. With voice and visual prompts “they were designed to be used by someone who’s never seen them before,” from sixth graders to senior citizens. It’s not all on you. Saving people from sudden cardiac arrest takes a community effort, Cabañas said. “When we see jurisdictions and cities and countries that have a higher survival rate, it’s because the community engages and the community is participating in those efforts.” That also means you don’t face an emergency alone, he said. Other lay responders, 911 dispatchers, first responders and medical workers all are part of the chain. “You’re not alone,” he said. “There’s going to be other people that will be around to support you in that mission of trying to save somebody’s life.”
Healthy Heart Continued from page 6 receive bystander CPR than those in predominantly white neighborhoods with higher income, and women are less likely to receive CPR than men. Chest compressions might require opening or cutting away someone’s bulky clothing or removing a bra to reach the middle of their chest or apply AED pads. “It is important that people also have an image of how they would do that,” Hunt said, because even though it may be a little uncomfortable, they can save a life. Don’t fret about mouth-to-mouth.
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Hospital News Continued from page 8 researchers making advances in so many different fields. These funds will help advance our work to better understand how cholesterol is produced,” said Dr. DeBose-Boyd, who holds the Beatrice and Miguel Elias Distinguished Chair in Biomedical Science at UTSW. Dr. DeBose-Boyd’s research focuses on the regulation of HMG-CoA reductase, which produces mevalonate, a crucial intermediate in the synthesis of cholesterol. Inhibitors of HMG-CoA reductase – collectively called statins – have revolutionized the treatment of high blood cholesterol levels. Statins trigger effects that result in the decrease of LDL-cholesterol, thereby reducing the incidence of heart attacks. Understanding how statins lower LDL levels was based on the Nobel Prize-winning research of UT Southwestern scientists Michael S. Brown, M.D., Professor of Molecular Genetics, and Joseph L. Goldstein, M.D., Chair and Professor of Molecular Genetics. The deficiency in mevalonate-derived products that accompany statin therapy leads to a compensatory increase in HMG-CoA reductase protein, resulting in the need for higher doses of the drug
to maintain cholesterol-lowering effects. Dr. DeBose-Boyd’s research aims to understand the mechanisms for this compensatory increase in HMG-CoA reductase, which could provide a foundation to develop novel therapies that enhance the therapeutic effectiveness of statins. “Hundreds of millions of patients worldwide take statins to protect their heart health. Dr. DeBose-Boyd’s research could eventually lead to drugs that work significantly better to achieve this goal,” said W. P. Andrew Lee, M.D., Executive Vice President for Academic Affairs, Provost, and Dean of UT Southwestern Medical School. Dr. DeBose-Boyd, who was elected to the National Academy of Sciences in 2023, joined UT Southwestern in the laboratory of Drs. Brown and Goldstein as a fellow of the Jane Coffin Childs Memorial Fund for Medical Research. He joined the UTSW faculty in 2003, received an Established Investigator Award from the American Heart Association in 2005, and was appointed a Howard Hughes Medical Institute Early Career Scientist in 2009. In 2022, Dr. DeBose-Boyd was recognized by the American Society for Biochemistry
and Molecular Biology with the Avanti Award in Lipids for outstanding research contributions in that field. He also mentors students in Biological Chemistry and Cell and Molecular Biology in the UT Southwestern Graduate School of Biomedical Sciences. Founded in 2004, TAMEST brings together the state’s brightest minds in medicine, engineering, science, and technology to foster collaboration and advance research, innovation, and business in Texas. With more than 335 members, eight Nobel Laureates, and 22 member institutions, TAMEST is composed of Texas-based members of the three National Academies (National Academy of Medicine, National Academy of Engineering, and National Academy of Sciences) and other honorific organizations. “Researchers at UT Southwestern and across Texas are pursuing ideas with the potential for global impact,” said Lyda Hill, entrepreneur and founder of Lyda Hill Philanthropies. “Through its critical work, TAMEST brings together many of our state’s leading innovators, and it is exciting to see the significant contributions of Dr. DeBose-Boyd and all of this year’s recipients.”
TAMEST President Brendan Lee, M.D., Ph.D., Baylor College of Medicine, said: “We are thrilled to announce this year’s recipients of our Hill Prizes and to support these top researchers in our state as we watch them change the world. These prizes will accelerate their groundbreaking contributions and put them in a stronger position to receive more research funding in large-scale grants and collaborations. We are proud to advance these exceptional innovators and ideas and highlight the most exciting research in the state thanks to the vision and support of Lyda Hill.” Drs. Brown and Goldstein are Regental Professors at UTSW. Dr. Brown is Director of the Erik Jonsson Center for Research in Molecular Genetics and Human Disease. Dr. Brown holds the W.A. (Monty) Moncrief Distinguished Chair in Cholesterol and Arteriosclerosis Research, and the Paul J. Thomas Chair in Medicine. Dr. Goldstein holds the Julie and Louis A. Beecherl, Jr. Distinguished Chair in Biomedical Research, and the Paul J. Thomas Chair in Medicine. Executives.
example, quality assurance of dosimetry auditing methodologies. • Collaboration in the Rays of Hope initiative of the IAEA through Anchor Centres. • Participation in the cost-free experts program of the IAEA through the provision of technical experts. “We are honored to be designated as an IAEA Collaborating Centre. This recognition not only validates the work we’ve already completed to advance global initiatives in cancer research and treatment but also inspires us with the possibilities ahead through these collaborative opportunities,” said Kathleen Schmeler, M.D., associate
vice president of Global Oncology and professor of Gynecologic Oncology and Reproductive Medicine. “We look forward to working together with the IAEA and their Member State institutions to make significant strides for cancer patients and their families around the world.” MD Anderson’s Strategic Plan calls for reaching more people and saving more lives, which is advanced by aligning with others to provide expertise in cancer prevention, education, research and treatment in the community setting. Today’s announcement further extends MD Anderson’s commitment to this work, which includes its international
collaboration to reduce the global burden of women’s cancers with the WHO. Aligned with the goals of World Cancer Day on February 4, MD Anderson’s efforts echo the broader mission of the international awareness day to alleviate the global impact of cancer while highlighting the need to take concerted actions to recognize, understand and resolve disparities in cancer care on a global level.
MD Anderson Continued from page 8 many IAEA publications, among them the Radiation Oncology Physics: A Handbook for Teachers and Students and the recent IAEA Human Health Report on National Networks for Radiotherapy Dosimetry Audits. MD Anderson will expand its support of IAEA through a jointly developed work plan that includes: • Training and educational activities in radiation oncology, radiation physics, radiology, nuclear medicine and nutrition. • Technical expertise and assistance in expanding scientific and technical capabilities in radiotherapy and radiology. • Research collaborations, for
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February 2024
Austin Medical Times
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Transparency
Continued from page 1 short timeframe. The patient may dispute any amount billed that is $400 or more than the GFE amount through the NSA’s patient-provider dispute resolution process (“PPDRP”). A failure to comply with this requirement is subject to $10,000 monetary penalty for each violation. At this point, we understand that CMS is engaging in inquiries with providers in response to patient complaints regarding the GFE. However, we are
unaware of any financial penalties having been imposed on any provider for failure to comply with this requirement. Similarly, the NSA requires plans to furnish an advanced explanation of benefits (“AEOB”) to commercially insured patients 3 days before the service or upon request if the service has not been scheduled. This would also require providers to send estimates of the scheduled item
/ services to the plan so that the plan could furnish the AEOB. However, CMS is delaying enforcement of these AEOB requirements until subsequent rulemaking. Nonetheless, providers should be prepared to, at some point, send estimates for both uninsured (self-insured) and commercially insured patients.
Accounting Liz Thachar dose of radiation to the heart in treatments of the breast, chest wall, and nearby lymph nodes. How Lifestyle Changes and Supportive Care Help Integrating lifestyle interventions is important when it comes to the heart. Encouraging patients to adopt healthy habits not only supports overall well-being but aids in maintaining heart health during and after cancer treatment. • Eat a healthy diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats; limit processed foods and excessive sodium • Exercise or engage in regular physical activity as able • Manage stress through techniques
like meditation, journaling, or deep breathing • Steer clear of tobacco and limit alcohol consumption When it comes to the heart and cancer treatment, balancing the effectiveness of cancer therapies with the preservation of heart function is essential to improving the long-term cardiovascular health of cancer patients. By understanding potential cardiac risks, preventive measures, and lifestyle modifications, healthcare providers and patients can make informed decisions when it comes to matters of the heart.
Age Well, Live Well Continued from page 11
February 2024
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Continued from page 3
inactivity, obesity and eating an unhealthy diet. It’s important to consult with a health care provider to determine the appropriate cancer screening tests based on individual health history and risk factors.” The most important cancer risk factors that can be changed are body weight, diet and physical activity. At least 18% of all cancers diagnosed in the U.S. are related to preventable conditions like excess body weight, physical inactivity, excess alcohol
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Oncology 2. Advanced Imaging Techniques: Imaging technologies, such as echocardiograms and cardiac MRIs, aid in early detection of cardiac changes, enabling timely interventions to prevent further complications. 3. Precision Medicine and Biomarkers: By analyzing the individual genetic makeup and biomarkers of cancer, oncologists can tailor effective treatments that are less harmful to the heart. 4. Proton therapy: Treatments like ultra-precise proton therapy limit potential impact outside the targeted tumor, avoiding the heart and lungs. According to a study, proton therapy consistently demonstrates the lowest average
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consumption and poor nutrition. Avoiding tobacco products, staying at a recommended weight, being active throughout life and eating a nutritious diet can greatly reduce the risk of developing or dying from cancer. These same behaviors are also linked with a lower risk of heart disease and diabetes. The Texas Health and Human Services Texercise statewide health and wellness initiative encourages people and communities to adopt
healthy lifestyle habits. People are encouraged to download the Texercise Health Chart using the Aging Well Resources Order Form to track their health information. The Texas Department of State Health Services also provides cancer resources for patients, caregivers and families.
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