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SEÑALIZACIÓN CELULAR
BIOLOGÍA CELULAR foto: www.pexels.com
CELL SIGNALING SEÑALIZACIÓN CELULAR A. Ordaz-Hernández1,3 C. Regalado-Santiago1 J. M. Loeza-Corte2,3 M. N. Fierro-Muñoz1 M. Herrera-Martínez1* 1 Instituto de Farmacobiología, 2Instituto de Tecnología de los Alimentos, 3Cuerpo Académico Tecnologías Agroalimentarias en Zonas Áridas. Universidad de la Cañada, Carretera Teotitlán - San Antonio Nanahuatipán Km 1.7 s/n., Paraje Titlacuatitla, Teotitlán de Flores Magón, Oaxaca, México, C.P. 68540.
ABSTRACT Cell signaling is a conserved and inherent mechanism in all the functions carried out by the cell, which allows its interaction with the surrounding microenvironment. The advance in the understanding of this essential process is largely due to the progress of molecular biology, the generation of new bioinformatics tools and the identification of both, the human genome and other organisms. Recently, new concepts have been described to help in a better understanding on the cell signaling mechanisms; likewise, some paradigms have been discarded in relation to this topic. Due the vast knowledge on cell signaling, the present review is focused on communication processes of multicellular organisms, where it is intended to mention key points that will allow understanding how this process operates, and some concepts established in the last decades. Keywords: Cell Biology, Cell Signaling, Ligand, Receptors, Intercellular Communication, Receptor Tyrosine Kinases, G Protein-Coupled Receptors, Intrinsically Disordered Proteins
RESUMEN Fecha de envío: 12 de febrero del 2019.
T E S T L A PA L L I | E N E R O - J U N I O 2 0 1 9
La señalización celular es un mecanismo conservado e inherente a todas las funciones celulares, que permite su interacción con el microambiente que lo rodea. El avance en la comprensión de este proceso esencial para la célula, ha sido en gran medida al progreso de la biología
