TECHNICAL ABSTRACTS Environmental toxicants such as pesticides pose a significant risk to human health. Pesticides are persistent organic compounds and are ubiquitous in our environment. They are used daily in our homes, work places, and school environments. They are found in air, water, soil, food sources, and biological materials. Pesticides are used extensively and are dispersed into the environment in great quantities. Therefore, analysis of pesticides as a biomarker is relevant and is needed for easy assessment of exposure. Analyses of pesticides in biological samples such as blood and urine have their limitations. They are invasive and non‐cumulative. Hair can accumulate pesticides and because of ease of sampling hair can be a good biomarker for analysis of pesticides and pesticide exposure. This study consists of developing an effective method for extracting pesticides from hair. Also, develop a sensitive method for the determination of pesticides in hair using gas chromatography with electron capture detector (GC‐ECD). This work was funded by RCMI Grant # R003045‐17 and NASA / TSU‐URC Grant # NCC9165. Technical Session 11 Thursday, p.m. 3:00 – 5:00 p.m. Aubert Organic Chemistry Session Chair Al fredWilliams, Ph.D. North Carolina Central University Presenters “Improving the physico‐chemical properties of anti‐cancer drugs via 3:00 p.m. – 3:15 co‐crystallization” p.m. Safiyyah Forbes, Christer B. Aakeröy*, and John Desper. Kansas State University, Department of Chemistry, Manhattan, KS 66502 Abstract Co‐crystallization has become an important method for improving the physico‐chemical properties (i.e. stability, solubility) of solid drug candidates. Crystal engineering is being used as a strategy for understanding and predicting hydrogen bonding interactions. The complementary pairing of two molecules held together by hydrogen bonding promotes the formation of a stable crystalline complex that contains both the active pharmaceutical ingredient (API) and the non‐toxic co‐crystallizing agent, Fig.1.
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