chromatography
20
Issue 6 2018
A solution for your daily bioseparations challenges THE Waters Acquity Arc Bio system is a versatile, iron-free, bio-inert, quaternary liquid chromatograph specifically engineered to enable the efficient transfer and improvement of bioseparation analytical methods, regardless of the LC platform on which the original method was developed. Engineered with bio-inert flow paths made of iron-free materials, the Acquity Arc Bio system keeps large molecules intact and on the move, for better sample recovery and minimal carryover, whether the chromatographic mode is reversed phase (RP), ion exchange (IEX), size exclusion (SEC) or hydrophobic interaction (HIC).
Built upon the reliable foundation of the Acquity Arc system, the Acquity Arc Bio system is designed with novel Arc Multi-flow path technology to provide the versatility and robustness required to efficiently transfer, adjust or improve your methods without compromising method integrity. • Experience true plug-and-play HPLC and UHPLC bioseparations • Modernise existing legacy methods • Accelerate analytical assays designed to assess biotherapeutic quality attributes related to safety, stability and efficacy The Acquity Arc Bio system is compatible with numerous detectors from Waters, including photodiode array, UV/Vis,
fluorescence, refractive index, evaporative light scattering and the Acquity QDa mass detector. In addition, the Acquity Arc Bio system features novel Auto Blend Plus™ technology that automatically blends up to four solvents in any combination or proportion and allows the operator to program in pH and ionic strength for ion-exchange or size exclusion-based methods, or program in the organic solvent concentration and pH for reversed-phase gradient separations. This significantly reduces human error and the task of preparing buffered mobile phases manually. The Acquity Arc Bio system is controlled through Waters Empower 3 and MassLynx software.
MICROSEP (PTY) LTD Louis van Huyssteen Tel: (011) 553 2300 Fax: (011) 553 2400 louis.vanhuyssteen@microsep.co.za www.microsep.co.za
USP recommends new ion chromatography method for zinc oxide assay More convenient and more reliable UNITED States Pharmacopeia (USP) has updated the General Chapter 591 ‘Zinc Determination’ monograph to include ion chromatography as the preferred method for measuring zinc oxide.
Why send samples to a lab when
you can measure CBD and THC yourself in minutes at a cost of less than R10 per analysis.
Lowest Cost System: R99 000.00 + VAT • GC • An electronic balance to weigh the sample • Six extraction bottles • Calibration standard (enough for 400 analyses) • Two injection syringes • Compact size Contact: I kevin@chromspec.co.za I 082 445 0714 I
website. The new method is convenient to use, reliable and is approved by the FDA. Advantages of using Metrohm IC for zinc oxide assay: • Precise software-controlled PCR delivery by patented Dosino technology • Simple reagent replenishment for easy use • Automatic cleaning of the flow-path to prevent reagent crystallisation for faster start up and reliability METROHM SA (PTY) LTD Tel: (011) 656 1918 CPT: (021) 852 0213 DBN: (031) 265 0067 Fax: (011) 656 2698 078 643 7113 info@metrohm.co.za www.metrohm.co.za
Jasco LC-4000 HPL/RHPLC/UHPLC systems
SRI GC Range dedicated to Cannabis Oil Analysis • Inexpensive • Easy to use • Dedicated to Cannabis Oil analysis
USP 41–NF 36 was developed in partnership with Metrohm and replaces manual titration methods. The new method is approved by the FDA and benefits users with more ease of use and reliability. Zinc oxide is used in various skincare creams, drugs and drug products. USP has replaced the existing manual titration methods with ion chromatography method and has rewritten the General Chapter 591. The ion chromatography analysis involves separation of zinc oxide followed by post-column reaction using 4-(2-pyridylazo) resorcinol (PAR) reagent and subsequent detection at 530nm wavelength. The new method is documented in the Metrohm Application Note AN-U-076, which can be downloaded from the Metrohm
There are 3 models of GC in this range: • The simplest is a plug-and-play system for measuring CBD and THC concentration in cannabis flower or concentrates. (Not for edibles, residual solvent or terpene analysis). • The mid-range GC to measure CBD & THC as well as cannabinoids, residual solvents and terpenes. • The professional model for analysis of cannabinoids, residual solvents and terpenes includes a 12 vial incubator for easier extraction of concentrates and edibles.
JASCO, the Japanese analytical instrument manufacturer, started production of the first chromatographic detectors in the 70s by using its experience in the field of spectroscopy. Within a short time, the firm entered the market with its fluid transport modules, and since then continuous development has characterised its chromatographic units. The key features of the currently produced LC-4000 chromatographic system includes the modular design, the wide detector selection, as well as the wide variety of gradient mixing options. The modules of the system not only provide solutions for the classical liquid chromatography
applications but also fulfil the requirements of the rapid chromatography (max.70MPa) and UHPLC (max.130 MPa). Due to more than half a century of experience and knowledge gained by Jasco in the chiral spectroscopy field, the available detectors include special ones such as the circular dichroism or the optical rotation detectors. The modules can be programmed individually from the control panel of the instruments and they have an independent memory and complete selfdiagnosis, enabling them to easily fit into the chromatographic systems of other manufacturers as well. With the Jasco ChromNav2 chromatography software package, the full system control, data processing, validation and documentation are possible.
ANALYTICAL SOLUTIONS CC Tel: +27 (0)87 610 0900 (National) info@analyticalsolutions.co.za www.analyticalsolutions.co.za
