SUPPORTING GUT HEALTH WITH SEAWEED EXTRACTS
A targeted approach by Marie Gallissot and Maria Garcia Suarez, Olmix Group
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mportance of gut health in modern production systems. Gut health has become increasingly important in the livestock industry with the emergence of antimicrobial resistance and the urge to limit the use of antibiotics. The intestinal mucosa converges various functions: digestion and absorption of nutrients; as well as physical barriers against microbes and toxins, thanks to the presence of a protective mucus layer and tight junction proteins that seal the paracellular space. The intestinal mucosa hosts both gut microbiota and immune cells (70% of the total number of immune cells are residents of the gut mucosa and gut-associated lymphoid tissue). In modern production systems, the gastrointestinal tract is being challenged and the subtle gut health balance being relied
Figure 1: Seaweed polysaccharides structure
on can be impaired. The components that define gut barrier and immune function can be weaken and lead to higher occurrence of digestive troubles associated with dysbiosis. This imbalance will trigger local and systemic inflammation, affecting the global health status and the growth performance of the animals. The challenge in the industry is to find solutions capable of supporting the epithelial barrier function and the gutassociated lymphoid tissue (GALT), in order to maintain a proper gut health and, thus, ensure good performance without the need of antibiotics.
Seaweeds: The multi-asset solution!
Many candidates are available, with varying efficacy and scientific evidence. Among them, seaweeds, or macroalgae, which have gained great interest in the past decades and are the object of increasing research. In the literature, seaweeds Figure 2: Mode of action of MSPÂŽIMMUNITY on intestinal epithelial cells. Adapted from Berri et al. (2016 and 2017).
22 | July 2019 - International Aquafeed