Nutramedic &Cosmetics At that time, the definition of psychobiotics was primarily based on the results of preclinical re search on laboratory animals, which suggested the potential of psychobiotics in the treatment of de pression and anxiety. In humans, the effects of psy chobiotics have been mainly investigated in collabo rative psychiatry, particularly in the treatment of so matic diseases such as irritable bowel syndrome. These days, we already have the first meta-analy ses in the field of psychobiotics. Several meta-ana lyses have pointed to the effectiveness of psychobi otics in reducing symptoms of depression. For in stance, one meta-analysis of 10 randomized place bo-controlled studies that investigated the impact of psychobiotics in alleviating symptoms of major depressive disorder showed that psychobiotics are indeed significantly more effective than a placebo, especially in male patients and with longer-term therapy. However, a meta-analysis of 12 randomized placebo-controlled studies did not demonstrate the same effectiveness of psychobiotics in treating an xiety, similar to the meta-analysis on psychobiotics in the treatment of anxiety in young individuals. A review of the literature gives the impression that psychobiotics are more effective in treating depres sion than anxiety. It is believed that psychobiotics are particularly effective in treating depression be cause their anti-inflammatory action influences its inflammatory component. On the market, there are products that contain psychobiotics whose efficacy has been scientifically proven. OMNi-BiOTiC® STRESS contains 9 different bacte rial strains of human origin, the effectiveness of which has been scientifically demonstrated through clinical studies. Numerous research studies have shown its positive impact not only on gastrointesti nal issues but also on reducing mental fatigue and overall tiredness, as well as on improving sleep. The addition of B-group vitamins, it protects cells from oxidative stress and contributes to normal psycho logical function and the normal functioning of the nervous system, normal metabolism, energy pro duction, reduction of fatigue and exhaustion, and the normal function of the immune system.
References:
Dinan et al., 2013, https://pubmed.ncbi.nlm.nih.gov/23759244/ Misera et al., 2021, https://pubmed.ncbi.nlm.nih.gov/34681176/ Liu et al., 2018, https://pubmed.ncbi.nlm.nih.gov/29995348/ Kadosh et al., 2021, https://pubmed.ncbi.nlm.nih.gov/34131108/ Nadeem et al., 2019, https://pubmed.ncbi.nlm.nih.gov/30499231/ Sikorska et al., 2023, https://pubmed.ncbi.nlm.nih.gov/36834489/
Centar Mikrobiom d.o.o. Sky Office, Toranj B R. F. Mihanovića 9, Zagreb, Croatia Mob.: + 385 98 13 73 344 Tel.: + 385 1 78 99 694 https://www.ccm.hr/
New Probiotic Concept within Cognitive Health Probi® Sensia offers a diversified solution for a wide range of consumer needs, from dietary supplements to functional foods and beverages.
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ental health supplements have emerged as the fastest-growing benefit within the global dietary supplements market. Over five years (20172021), we’ve seen a 30 percent growth in probiotic launches positioned within Brain-Mood Health1, showing how psychobiotics is a fast-rising niche2. Within the scientific community, the connection between gut and neurocogni tive functions has been a major research topic during the last couple of years. Stress, anxiety and depression-like symptoms were the first to be addressed, but today there are more and more research being carried out in healthy individuals, as the focus has shifted towards finding solutions to the “everyday” issues that many of us struggle with - poor sleep quality, moody-behavior and issues with cog nitive functions such as memory and focus. Probi® Sensia is a new probiotic concept by Probi® based on clinical and scien tific data that supports improved cognition by boosting learning and working memory as well as improved mood and sleep. These cognitive functions are im portant in enhancing people´s overall mental health. The new probiotic solution is available to meet diverse consumer needs, supported by global health-related claims and customizable with local support. Furthermore, it can be combined with selected vitamins, minerals or other ingredients, and is ideal for dietary sup plement formats like capsules, stick packs and functional foods such as beverag es and powder products. Probi® Sensia is based on the well-documented probiotic strain Lactiplantiba cillus plantarum HEAL9 (HEAL9™). Three clinical studies and totally five scientific articles have repeatably showed that intake of HEAL9™ affects the so-called gut- brain axis in a positive way. The clinical endpoints include decreased cortisol and stress-induced inflamma tion in chronically stressed but otherwise healthy students, as well as decreased symptoms of depression and anxiety. In the latest publication healthy individuals with moderate stress were evaluated. Improved memory and cognitive function, improved sleep quality and decreased daytime dysfunction, as well as improved mood was found after intake of the HEAL9™ strain. “We are proud to launch our new concept Probi® Sensia, based on a strong clini cally proven effect, which optimizes and maintains important cognitive functi ons such as memory as well as mood, sleep and stress. With Probi® Sensia we now offer a wide-ranging solution to help our customers to meet diverse consumer needs from a health-related perspective with a broad usage from dietary supple ments to functional foods and beverages." said Anita Johansen, CEO of Probi. The latest study “Intake of Lactiplantibacillus plantarum HEAL9 Improves Cog nition in Moderately Stressed Subjects: A Randomized Controlled Study was re cently published in Nutrients (2023) 15 (15), 3466. Read the complete study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421450/
References: 1
Innova Market Insight 2022
2
Further insights: “The gut-brain axis: Psychobiotic opportunity in 25 countries” (March 2022)
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