A Guide to Innovet Products by Innovet Italia

A GUIDE TO INNOVET PRODUCTS RESEARCH-BASED HEALTH AND WELL-BEING ACCORDING TO NATURE January 2024 S

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A GUIDE TO INNOVET PRODUCTS RESEARCH-BASED HEALTH AND WELL-BEING ACCORDING TO NATURE S

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RE NATU TO

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JOINTS Condrogen® Energy Condrostress® (+) Condrostress® (+) Cat Glupacur®

02 03 04 05

NERVOUS SYSTEM Alevica® Senilife® Plus

06 07

SKIN & COAT Redonyl® Ultra Retopix® Mousse Retopix® Fluid Retopix® Spray Retopix® Oto Redoderm® Shampoo Repy® Gel Repy® Dress

08 09 10 11 12 13 14 15

GUT Normalia® Fast Normalia® Extra

16 17

ORAL CARE Restomyl® Gel Restomyl® Toothgel Restomyl® Dentalbones Restomyl® Dentalcroc Restomyl® Supplement

18 19 20 21 22

EYES Oculvet® Gel Oculvet® Drops Oculvet® Wipes

23 24 25

URINARY TRACT Nefrys® Urys®

26 27

CONTENTS

METABOLISM Oleea®

RESEARCH & INNOVATION

FOR THE HEALTH OF OUR FOUR-LEGGED FRIENDS TO GO WHERE NATURE LEADS ...

... means studying and reproducing the body's natural protective responses, as opposed to counteracting artificially the negative stimuli that may affect it.

ALIA MECHANISM

The insight of the Nobel Prize Laureate in Medicine Rita Levi Montalcini led, in the nineties, to the development of a new concept of biological modulation of some neuroimmune inflammatory cells (e.g. mast cells) called the ALIA* mechanism: an endogenous system of local injury antagonism that the body activates to counteract the negative stimuli. The first identified compound acting this physiological mechanism is PEA (palmitoylethanolamide).

ENDOCANNABINOIDS

We now know that PEA is an endocannabinoid (eCB), an authentic defence mechanism that Nature has devised to counteract negative stimuli and thus keep the body healthy.

ALIAMIDES

From PEA originate the ALIAmides, a family of substances that naturally and physiologically modulates the responses of cells and tissues to negative stimuli, thus ensuring a physiological balance in the body. native PEA PEA-um

PEA-um, the most active form Native PEA is poorly bioavailable. Through the ultra-micronization process, Innovet Research managed to obtain a much more active form patented all over the world (PEA-um, ultra-micronized palmitoylethanolamide).

* Autacoid Local Injury Antagonism

ALIAMIDES

ACCORDIN NCE G CIE

RE NATU TO

HEALTH

NEGATIVE STIMULI

(e.g. PEA-um)

PEA-um Adelmidrol PGA-m PGA-cur PEA-q Olaliamid

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THE BODY’S HEALTH DEPENDS ON THE BALANCE BETWEEN NEGATIVE STIMULI AND PHYSIOLOGICAL PROTECTIVE SYSTEMS

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Oleea

To keep overweight pets healthy.

Package sizes and dose forms Oleea® Liquid 60 ml with dosing syringe Oleea® Caps 60 skittle capsules

• Contains Olaliamid®: an innovative, patented compound developed by Innovet research.

Supports diets (lowcalorie diet) and other measures (physical activity) for reducing weight.

• Improves the result of weight-loss diets.

What it contains

How to use

• Olaliamid® Patented derivative of olive oil rich in NAE (N-acylethanolamines), which are physiological substances that help to maintain an efficient sugar and fat metabolism.

Administer preferably 30 to 60 minutes before meals. Shake well, insert the graduated syringe in the hole in the bottle adapter, turn the bottle upside down and draw the daily quantity indicated in the table. Empty the content of the syringe directly in the pet’s mouth. Open the skittle capsule as illustrated in the drawing (1) and squeeze its content into the animal’s mouth or mix it with its food ration (2). Alternatively, the skittle capsules can be swallowed whole.

• Vitamin E Neutralizes free radicals (antioxidant action).

METABOLISM

Reduces the health risks posed by overweight/ obesity.

Its unique features

• Safe and risk-free, can be administered for long periods. • Two dose forms for easy administration (squeeze skittle capsules and liquid).

Body weight (kg) 5-9 10 - 14 15 - 19 20 - 34 35 - 52 > 52

ml/day 0.5 1 1.5 -

Caps/day -

1 2 3

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Condrogen Energy

Healthy joints for puppies, and particularly active adult dogs.

Package sizes and dose forms Condrogen® Energy 30 scored tablets Condrogen® Energy 60 scored tablets Condrogen® Energy 90 scored tablets

Its unique features • Acts on both the muscles and the cartilage.

JOINTS

Ensures the healthy musculoskeletal development of puppies of large/giant dog breed.

• Safe for prolonged use (useful as early treatment for dogs prone to joint problems).

Protects the joints of particularly active dogs (e.g. sporting dogs) or overweight dogs.

• Formulated also for dogs with excessive joint wear (e.g. rescue dogs or overweight dogs).

What it contains

How to use

• Oxiforce complex® Exclusive combination of SOD (superoxide dismutase) and nucleotides. It guarantees joint stability by stimulating the energy metabolism of the muscles and neutralizing the free radicals.

Administer directly into the mouth or mixed with food for the following periods:

• Chondroitin sulfate and Glucosamine HCl Contribute synergistically to nourish the joint cartilage, maintaining the correct cartilage metabolism.

• Adult: for consecutive 60-90 day cycles to be repeated when needed.

• Puppy: during the developmental stages (from 2 to 12-18 months of age).

Body weight (kg) 0-8 9 - 18 19 - 29 30 - 44 45 - 60 > 60

Tabs/day ½ 1 1 and ½ 2 2 and ½ 3

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Condrostress (+)

To improve joint mobility of adult and senior dogs.

Package sizes and dose forms Condrostress® (+) 30 scored tablets Condrostress® (+) 60 scored tablets Condrostress® (+) 90 scored tablets

Protects joint cartilage.

• Safe for prolonged administration to senior dogs. • Improves the quality of life in dogs with reduced joint mobility.

What it contains

How to use

• Ovopet® (eggshell membrane) Biological matrix, a natural source of collagen, glycosaminoglycans (chondroitin sulfate, hyaluronic acid) and sulfur-bearing amino acids. It protects joint cartilage from the damage caused by wear.

Administer directly into the mouth or mixed with food at the quantity indicated in the table for periods of 60-90 days.

• Omega-3 fatty acids (EPA and DHA) Support the correct function of the synovial membrane.

JOINTS

Preserves the ability to move of dogs with chronic joint problems.

Its unique features

Body weight (kg) 0-6 7 - 14 15 - 22 23 - 30 31 - 39 ≥ 40

Tabs/day ½ 1 1 and ½ 2 2 and ½ 3

• Vitamin E Neutralizes free radicals (antioxidant action).

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Condrostress (+) Cat To improve joint mobility to adult and senior cats.

Package sizes and dose forms Condrostress (+) Cat 30 openable capsules

Protects joint cartilage.

• Safe for prolonged administration to senior cats. • Improves the quality of life of cats with reduced joint mobility.

What it contains

How to use

Open the capsule and pour its contents onto the food or directly into the animal’s mouth. Administer for 60-90 day cycles at the quantity indicated in the table.

• Omega-3 fatty acids (EPA and DHA) Support the correct function of the synovial membrane. • Vitamin E Neutralizes free radicals (antioxidant action).

JOINTS

Preserves the ability to move of cats with chronic joint problems.

Its unique features

The capsule is not edible. Once opened and emptied, dispose of the capsule in the organic waste.

Body weight (kg) 0-6 >6

Caps/day 1 2

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Glupacur

Joint relief for dogs and cats of all ages.

Package sizes and dose forms Glupacur® 30 scored tablets Glupacur® 200 scored tablets Glupacur® 30 stick packs

Helps to maintain the physiological pain threshold. Protects joint cartilage.

• Patented formula containing highly bioavailable PGA-cur. Physiological action.

JOINTS

Preserves the ability to move in cats and dogs with acute joint problems.

Its unique features

• Triple action on cartilage, inflammatory cells and oxidation. • Efficacy demonstrated by numerous clinical trials. • Safe and risk-free even for long-term administration.

What it contains

How to use

• PGA-cur Patented combination of Palmitoyl-glucosamine (PGA) and curcumin (cur). It reduces the reactivity of the synovial mast cell. It releases glucosamine, which has a protective action on the joint cartilage.

Administer for 60-90 days at the quantity indicated in the table.

• Curcumin Neutralizes free radicals (antioxidant action).

STICK PACK: the contents can be administered directly into the mouth of the animal or mixed with the food. TABLETS: the chewable tablet can be administered directly into the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal. Body weight (kg) 1-7 8 - 14 15 - 17 18 - 21 22 - 24 25 - 28 29 - 31 32 - 35 36 - 39 ≥ 40

Stick/day Tabs/day 1 2 1 1 and ¼ 1 and ½ 1 and ¾ 2 2 and ¼ 2 and ½ 2 and ¾ 3

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Alevica

To maintain the physiological function of the nervous system.

Package sizes and dose forms Alevica® Liquid 100 ml Alevica® 20 scored tablets Alevica® 40 scored tablets Alevica® 200 scored tablets

Maintains the correct pain threshold.

• Patented formula containing highly bioavailable PEA-q. Physiological action. • Efficacy confirmed by numerous scientific studies.

Protects the cells of the nervous system from oxidative damage (antioxidant action).

• Safe and risk-free even for long-term administration.

What it contains

How to use

• PEA-q Patented PEA (Palmitoylethanolamide) co-micronized with quercetin (q). Reduces the reactivity of the non-neuronal cells (mast cell and microglia) responsible for activating the neurons.

Administer the product at the daily quantity indicated in the table. TABLETS: the chewable tablet can be administered directly into the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal.

• Quercetin Neutralizes free radicals and protects the nervous system against oxidative stress.

NERVOUS SYSTEM

Supports the physiological nociceptive function.

Its unique features

• Formulated for fragile pets (e.g. senior pets or pets with metabolic diseases).

Body weight (kg) Tabs/day 1-6 ¼ 7 - 14 ½ 15 - 25 1 26 - 40 1+½

Body weight (kg) 41 - 60 61 - 75 > 75

Tabs/day 2 2+½ 3

LIQUID: shake well, insert the graduated syringe in the hole in the bottle adapter, turn the bottle upside down and draw the daily quantity indicated in the table. Administer the contents of the syringe directly into the animal’s mouth or mix it with the food. Body weight (kg) ml/day 0-5 0.5 6 - 10 1 11 - 15 1.5 16 - 20 2 21 - 25 2.5

Body weight (kg) ml/day 26 - 30 3 31 - 35 3.5 36 - 40 4 41 - 45 4.5 46 - 50 5

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Senilife Plus

To improve the cognitive functions and memory of senior cats and dogs, for successful brain ageing.

Package sizes and dose forms Senilife® 30 skittle capsules Senilife® 60 skittle capsules

Improves cognitive performance. Improves memory.

• Patented formula containing PEA-um (ALIA effect). Physiological action. • Safe in senior (fragile) pets even for long-term administration.

NERVOUS SYSTEM

For the mental health of senior cats and dogs.

Its unique features

• Efficacy demonstrated by numerous clinical trials. • Squeezable skittle capsules easy to administer.

What it contains

How to use

• PEA-um Bioavailable active form of PEA, it improves the short and long-term memory, both in the early and late stages of brain ageing.

Administer for 90-day cycles at the daily quantity indicated in the table.

• Vitamin E Neutralizes free radicals and slows down the natural cognitive decline in senior pets.

Open the skittle capsule as illustrated in the drawing (1) and squeeze the contents into the animal’s mouth or mix it with its ration of food (2). Alternatively, the skittle capsules can be swallowed whole.

• Phosphatidylserine, Pyridoxine and DHA Promote neurotransmission.

Body weight (kg) 0 - 10 11 - 20 21 - 30 > 30

Caps/day 1 2 3 4

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Redonyl Ultra

For healthy coat and skin.

Package sizes and dose forms Redonyl® Ultra 50 - 60 skittle capsules Redonyl® Ultra 150 - 60 skittle capsules

Reduces skin redness. Improves the quality of the skin and coat.

• With PEA-um (ALIA effect) physiological soothing action. • Tested and documented efficacy (international publications).

SKIN AND COAT

Soothes itching.

Its unique features

• Safe, even if used for prolonged periods. • Squeezable skittle capsules easy to administer.

What it contains

How to use

• PEA-um (ultramicronized palmitoylethanolamide) Maintains the physiological reactivity of skin mast cells.

Administer for 60-day cycles at the quantity indicated in the table.

• Biotin and essential fatty acids Moisturizing and restructuring action.

Open the skittle capsule as illustrated in the drawing (1) and squeeze the contents into the animal’s mouth or mix it with its food ration (2). Alternatively, the skittle capsules can be swallowed whole. 1

Body weight Redonyl® Ultra (kg) 50 mg 0-6 1 caps/day 7 - 12 2 caps/day 13 - 19 20 - 35 > 35 -

Redonyl® Ultra 150 mg 1 caps/day 2 caps/day 3 caps/day

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Retopix Mousse

To normalize skin areas affected by redness, dandruff and/ or foul-smelling greasy/oily secretions.

Package sizes and dose forms Retopix® Mousse 150 ml

Reduces the bad smell in skin folds and around the ears above all.

• Contains Adelmidrol (ALIA mechanism). Physiological action. • Efficacy tested by clinical trials. • Safe for long-term use even in puppies and kittens.

Soothes skin redness.

• Easy to apply, it is rapidly absorbed (ideal also for cats).

What it contains

How to use

• Adelmidrol Reduces the reactivity of skin mast cells. Soothing action.

Apply to the dry coat two or more times a day for at least ten days. Shake and turn upside down the bottle and spray the mousse onto a hand or directly onto the pet’s coat. Apply having parted the fur with your fingers or moving your hand against the grain of the hair, and spread uniformly rubbing it in gently. Do not rinse. Retopix® Mousse can be used in combination with the other products containing Adelmidrol in the Retopix line® (Spray, Fluid, Oto). The pet should also be washed regularly with Redoderm® Shampoo. External use, avoid contact with the eyes.

• Echinacea, Undecylenic acid and Octopirox A sanitizing complex that helps to maintain a balanced surface microflora. • Tapioca starch Protects the skin from excessive moisture and helps to remove excess oil and dandruff (adsorbing action).

SKIN AND COAT

Removes surplus sebum and favors the elimination of flakes.

Its unique features

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Retopix Fluid

To normalize the skin barrier of areas affected with redness, disepithelialization, dryness or scaling.

Package sizes and dose forms Retopix® Fluid 10 vials of 2 ml each

Moisturizing and re-epithelializing action. Soothing and anti-redness action.

Its unique features • Contains Adelmidrol (ALIA mechanism). Physiological action. • Efficacy demonstrated by scientific studies.

SKIN AND COAT

Maintains an effective skin barrier function.

• Safe even for prolonged application. • Easy application with resealable vials.

What it contains

How to use

• Adelmidrol Reduces the reactivity of skin mast cells, thereby exerting a soothing and anti-redness action.

Apply a drop of fluid per cm² of skin to be treated. Massage gently for a few moments. Repeat application twice a day for at least 10 days. The vial is resealable and can be used for several applications. External use, avoid contact with the eyes.

• Phytosphingosine A natural component of the epidermis that favors an intact skin barrier and limits the trans-epidermal water loss. • Hyaluronic acid and Traumatic acid Maintain skin integrity, hydration and elasticity.

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Retopix Spray

To normalize areas of skin affected with redness, greasy/oily secretions and a foul smell.

Package sizes and dose forms Retopix® Spray 100 ml

Helps to maintain the balance of surface microbial flora (sanitizing action). Indicated in case of foul-smelling greasy/oily secretions.

Its unique features • Contains Adelmidrol (ALIA mechanism). Physiological action. • Safe for prolonged use. • Easy to apply also to large areas.

What it contains

How to use

• Adelmidrol Reduces the reactivity of skin mast cells (soothing and anti-redness action).

Apply 1 spray every 10 cm² of skin. Before spraying, expose the skin by parting the fur with your thumb and index finger, or passing the hand against the grain of the hair. Rub gently for a few moments to spread the product more evenly. Repeat application 2 or 3 times a day for at least 10 days. External use, avoid contact with the eyes.

• Phytosphingosine A natural component of the epidermis that favours an intact skin barrier and limits the transepidermal water loss.

SKIN AND COAT

Soothes redness and skin irritation.

• Triclosan, Usnic acid and Undecylenic acid A sanitizing complex that helps to maintain a balanced skin surface microflora.

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Retopix Oto

Normalizes the outer ear affected by redness, waxy secretions and a foul smell.

Package sizes and dose forms Retopix® Oto 15 ml

Maintains a correct dermal function (soothing and anti-redness action). Favours the dissolution of wax and its elimination from the ear canal.

• Contains Adelmidrol (ALIA mechanism). Physiological action. • Safe even for prolonged use.

SKIN AND COAT

Its unique features

• Can be combined beneficially with drug therapy.

Helps to maintain a balanced microbial flora of the outer ear. What it contains

How to use

• Adelmidrol Reduces the reactivity of skin mast cells.

Apply 4-8 drops outside the ear canal, twice a day. Rub the base of the ear gently for a few moments to spread the product in the lower part of the outer ear canal. Repeat application for at least 10 days.

• Transcutol Biocompatible solvent with ceruminolytic action. • Triclosan, Usnic acid and Undecylenic acid A sanitizing complex that helps to maintain a balanced skin surface microflora.

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Redoderm Shampoo

For gentle cleansing of the skin and coat.

Package sizes and dose forms Redoderm® Shampoo 250 ml Redoderm® Shampoo 2000 ml

Reduces the allergen load (removes irritants, dust and pollen).

Its unique features • Safe even for frequent washes. • Does not alter the physiological lipid composition of the skin. • Leaves the coat shiny and silky.

SKIN AND COAT

Useful as medicated shampoo for allergic animals.

Favours a balanced skin barrier.

What it contains

How to use

• Titalin®-Zn and Ceramides Promote the integrity of the skin barrier and limit water loss.

Apply in a small quantity to the coat when wet. Rub in gently until a foam distributed uniformly across the whole body is obtained. Leave to act for at least one minute, then rinse with lukewarm water. Dry immediately. Repeat once a week as needed.

• Echinacea purpurea, Undecylenic acid and Octopirox A sanitizing complex that helps to maintain a balanced surface microflora. • Normalising cleansing base Cleanses thoroughly while respecting the skin’s natural lipid composition.

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Repy Gel ®

Improves the functional and aesthetic result of skin re-epithelialization.

Package sizes and dose forms Repy® Gel 30 ml Repy® Gel 75 ml

Soothing and anti-redness action on injured skin. Repellent action against licking and insects.

Its unique features • Contains Adelmidrol (ALIA mechanism). Physiological action. • Safe, even if used for prolonged periods. • With a repellent effect to preserve the wound.

What it contains

How to use

• Adelmidrol Optimizes re-epithelialization and improves the elasticity of the skin tissue.

Apply an adequate amount of product to the area of skin affected. Repeat the application 2 or more times a day.

• Hyaluronic acid and traumatic acid Maintain skin integrity, hydration and elasticity.

SKIN AND COAT

Promotes effective skin repair in case of various kinds of lesions.

• Echinacea purpurea, Usnea barbata and snail slime Promote the balance of surface skin microflora. • Olio di Neem Neem Oil gives the product a repellent action against licking and insects (e.g., flies).

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Repy Dress ®

Improves the functional and aesthetic result of skin re-epithelialization.

Package sizes and dose forms Repy® Dress 10x10 cm. 5 units Repy® Dress 10x10 cm. 25 units

Protects the wound mechanically from external insults. Absorbs exudates, thus promoting an ideal microenvironment.

Its unique features • Does not adhere to the wound so it is easier for the owner to monitor. • Easy to apply even to rough areas. • Adapts to the pet’s movements, ensuring perfect adhesion.

What it contains

How to use

• Polymer gel Absorbs exudates and does not adhere to the injured skin.

Remove the dressing from the sachet and peel off the transparent film. Apply to the clean wound with the gel in direct contact with the skin. Secure in place with a plaster or elastic bandage. Check the wound daily by lifting one corner of the dressing until the area to be inspected is completely visible. Replace the dressing when saturated with exudate (once a day for highly exudative wounds; every 3-7 days for dry wounds).

• Glycerine Protects from the overgrowth of microorganisms.

SKIN AND COAT

Promotes effective skin repair in case of various kinds of lesions.

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Normalia Fast

Promotes normal gut function during acute diarrhoea.

Package sizes and dose forms Normalia® Fast 10 openable capsules Normalia® Fast 100 openable capsules

Useful during acute diarrhoea. Indicated in the flare-up of chronic forms.

• With PGA-m (ALIA effect). Physiological action. • Dual action: maintains the physiological reactivity of the mast cells of the gut and protects the intestinal wall. • 100% vegetable capsules that can also be used in pets with food allergies/intolerances.

What it contains

How to use

• PGA-m (micronized palmitoylglucosamine) Highly bioavailable patented micronized compund. It maintains the physiological reactivity of the mast cells of the gut and releases glucosamine, which has a protective action (it restores the layer of mucus in the intestinal wall).

Administer the product for 5-10 days at the daily quantity indicated in the table.

• Bentonite and Tannic Acid Adsorbent and astringent action.

Concomitant oral use with macrolides should be avoided.

• Electrolyte complex Rehydrating action.

GUT

Rapidly improves the stool consistency.

Its unique features

The capsule should preferably be administered whole, placing it at the base of the tongue so that it is swallowed. Alternatively, the capsule can be opened, mixing its contents with the food.

Body weight (kg) 0 - 10 11 - 20 > 20

Caps/day 1 2 3

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Normalia Extra

Promotes normal gut function during chronic diarrhoea.

Package sizes and dose forms Normalia® Extra 30 stick packs Normalia® Extra 60 stick packs Normalia® Extra 30 scored tablets Normalia® Extra 200 scored tablets

Useful during chronic diarrhoea. Essential in changes in diet (including weaning).

Its unique features • With PEA-um (ALIA effect). Physiological action.

GUT

Helps to maintain normal intestinal reactivity.

• Safe even for prolonged administration. • Contains no meat, meat derivatives or lactose (safe in intolerant animals).

Normalizes gut microbiota.

What it contains

How to use

• PEA-um (ultra-micronized palmitoylethanolamide) Active form of PEA. Reduces the reactivity of the mast cells of the gut and restores the correct permeability of the intestinal barrier.

Administer the product for at least 30 days at the quantity indicated in the table.

• Bacillus subtilis Probiotic action. Viable spore-forming bacterium resistant to high temperatures and gastric acidity. • Bovine colostrum Prebiotic with immunomodulatory activity. Improves the stability and biodiversity of the gut microbiota. • Electrolyte complex Rehydrating action.

The contents of the sachet can be administered directly in the animal’s mouth or mixed with the food. The chewable tablet can be administered directly in the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal. Body weight (kg) 0 - 10 11 - 15 16 - 20 21 - 25 26 - 30 31 - 35 > 35

Stick/day Tabs/day 1 2 1 1+¼ 1+½ 1+¾ 2

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Restomyl Gel

Relieves redness of the oral mucosa.

Package sizes and dose forms Restomyl® Gel 30 ml

Controls irritation of the gums.

• Contains Adelmidrol (ALIA mechanism). Physiological action. • Does not contain ingredients or by-products of animal origin. Suitable for pets with food intolerances/allergies.

Useful after dental procedures (e.g. tooth scaling and polishing).

• Efficacy demonstrated by studies published in international journals.

What it contains

How to use

• Adelmidrol Maintains the physiological reactivity of the mucosal mast cells.

Raise the lip by applying slight pressure with the tip of the applicator, taking care to ensure that the gel outlet is directed towards the mouth. Press the applicator one or more times according to the size of the pet. Due to its marked mucoadhesive properties, the gel is distributed quickly across the entire oral mucosa. Repeat the application 2-3 times a day.

• Traumatic acid Plant-based substance with repair effect on oral mucosa. • Phytosphingosine Sanitizing action; it helps to maintain a balanced oral microbial flora, thus reducing the buildup of plaque.

ORAL CARE

Helps to restore the integrity of oral mucosa.

Its unique features

• Hyaluronic acid Mucoadhesive action that increases the residence time and thus the action of the other functional ingredients.

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Restomyl Toothgel

Removes the plaque and protects the gums.

Package sizes and dose forms Restomyl® Toothgel 50 ml with toothbrush Restomyl® Toothgel 50 ml

Anti-plaque, anti-bacterial and whitening action. Protects the oral mucosa (soothing and anti-redness action).

• Contains Adelmidrol (ALIA mechanism). Physiological action. • Designed for daily use, safe even if swallowed. • Toothbrush specially developed not to damage the enamel (extra soft bristles) with a user-friendly grip.

What it contains

How to use

• Adelmidrol Maintains the physiological reactivity of the mucosal mast cells.

Apply the gel to Restomyl® Toothbrush, brushing gently across the entire tooth surface. To ensure a good oral hygiene of cats and dogs, the teeth should be brushed once a day (AAHA* guidelines).

• Bromelain Plant-based substance with a whitening action. • Triclosan Helps to maintain a balanced oral microbial flora, thus reducing the formation of plaque.

ORAL CARE

For daily cleaning of the teeth of cats and dogs.

Its unique features

*AAHA (American Animal Hospital Association) Dental care guidelines for dogs and cats, JAAHA 2019

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Restomyl Dentalbones ®

Chewable bones for daily tooth cleaning.

Package sizes and dose forms Restomyl® Dentalbones 482 g Restomyl® Dentalbones Mini 340 g

Slows down the buildup of tartar.

• Dual action (mechanical and systemic) against dental plaque. • Efficacy demonstrated by published clinical trials.

ORAL CARE

Prevents the formation and adhesion of plaque on the teeth surface.

Its unique features

• Approved by the VOHC (Veterinary Oral Health Council).

Improves breath freshness.

• Free of substances that mask halitosis.

What it contains

How to use

• AN ProDen® (Ascophyllum nodosum) Specific alga of the North Sea with a systemic action. through the bloodstream, its functional ingredients concentrate in the saliva where they carry out their anti-plaque action.

Starting from the appearance of the permanent teeth, administer Restomyl® Dentalbones at the daily quantity indicated in the table. Restomyl® Dentalbones can be administered alternated with Restomyl® Supplement or Restomyl® Dentalcroc as an oral health “treat”. For toy dogs, the bone should be broken into smaller pieces. Always leave fresh water for the dog. Body weight (kg) <14 >14

Daily quantity ½ bone 1 bone

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Restomyl Dentalcroc ®

A treat for oral health and hygiene.

Package sizes and dose forms Restomyl® Dentalcroc Dog 60 g Restomyl® Dentalcroc Dog 150 g Restomyl® Dentalcroc Cat 60 g

Slows down the buildup of tartar. Improves breath freshness.

• Approved by the VOHC (Veterinary Oral Health Council). • Extremely palatable and 100% vegetable.

ORAL CARE

Prevents the formation and adhesion of plaque on the tooth surface.

Its unique features

• Low-calorie content. • Free of substances that mask halitosis.

What it contains

How to use

• AN ProDen® (Ascophyllum nodosum) Specific alga of the North Sea with a systemic action. Through the circulation, its functional ingredients concentrate in the saliva where they carry out their anti-plaque action.

Starting from the appearance of the permanent teeth, administer Restomyl® Dentalcroc once a day in the quantities indicated in the table. Restomyl® Dentalcroc can be administered alternated with Restomyl® Supplement, as an oral health “treat”. To maintain a healthy mouth Restomyl® Dentalcroc is to be used daily for long periods of time (at least 8 months).

Body weight Dentalcroc 60 g (kg) Cat and Dog 0-5 2 - 4 croq. 6 - 10 4 - 8 croq. 11 - 25 > 25 -

Dentalcroc 150 g Dog 2 - 4 croq. 4 - 5 croq.

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Restomyl Supplement ®

Nutritional supplement for oral health and hygiene.

Package sizes and dose forms Restomyl® Supplement Dog 60 g Restomyl® Supplement Cat 40 g

Slows down the buildup of tartar.

• Efficacy demonstrated by numerous published clinical trials.

ORAL CARE

Prevents the formation of plaque.

Its unique features

• Approved by the VOHC (Veterinary Oral Health Council).

Improves breath freshness.

• 100% vegetable.

What it contains

How to use

Starting from the appearance of the permanent teeth, administer Restomyl® Supplement, mixed with food (wet or dry), at the daily quantities indicated in the table. To be used daily for long periods. The results are generally obtained during the 3rd week of use.

• Free of substances that mask halitosis.

Restomyl® Supplement can be administered alternated with Restomyl® Dentalcroc.

Body weight (kg) 0 - 10 11 - 25 > 25

Supplement Dog ½ measure 1 measure 2 measures

Supplement Cat 1 measure / /

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Oculvet Gel ®

Protects the ocular surface in case of dry eye.

Package sizes and dose forms Oculvet® Gel 10 ml

Relieves the symptoms of dry eye. Maintains the integrity of the cornea surface.

• Acts on all three layers (lipid, water and mucin) of the tear film.

EYES

Lubricant and humectant action.

Its unique features

• Long-lasting effect. • Contains Adelmidrol (ALIA mechanism). Physiological action. • Soft applicator nozzle.

What it contains

How to use

• MCT (medium-chain triglycerides) Reintegrate the lipid layer by limiting evaporation (less frequent applications).

Pull the lower eyelid down gently and apply a small quantity of gel in the conjunctival sac at least twice a day, taking care not to touch the eye with the applicator nozzle. Close the eyelid and rub gently to distribute the gel uniformly across the eye surface. Before you apply the product, remove any secretions from the area using a sterile wipe (e.g. Oculvet® Wipes).

• Hyaluronic acid & Carbomer Mucoadhesive polymer gel with a long-lasting moisturizing effect. • Adelmidrol Increases the endogenous levels of PEA, a natural component of the eye (its reduction causes dry eyes).

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Oculvet Drops

Gives relief to red eyes.

Package sizes and dose forms Oculvet® Drops 10 ml

Useful against pollen, dust, wind, etc.

• Contains Adelmidrol (ALIA mechanism). Physiological action.

EYES

Soothes the redness of eye tissues.

Its unique features

• Free of side effects; ideal also for repeated applications. • Can be used together with any medicinal product.

What it contains

How to use

• Adelmidrol Completely physiological soothing and anti-redness action.

Pull the lower eyelid down gently and instil 1 or 2 drops in the conjunctival sac at least twice a day, taking care not to touch the eye with the dropper. Before you apply the product, remove any secretions from the area using a sterile wipe (e.g. Oculvet® Wipes).

• Hyaluronic acid Lubricant action.

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Oculvet Wipes

For cleansing the periocular area (e.g. eyelids, eyelashes).

Package sizes and dose forms Oculvet® Wipes, 14 sterile wipes

Useful for minimizing tear staining caused by excessive tearing. Indicated to remove irritants, dust and pollen.

• Contains Adelmidrol (ALIA mechanism). Physiological action.

EYES

To remove eye discharge also before applying eye drops or ophthalmic gels.

Its unique features

• Soft TNT wipes (not harmful for the cornea). • Sterile, ideal for use before and after surgery.

To clean around the eyes before and after surgery and in case of blepharitis/ conjunctivitis.

What it contains

How to use

• Adelmidrol Completely physiological soothing and anti-redness action.

Wash your hands and remove the wipe from the sachet. Cleanse the periocular area gently. For a better soothing action, the sachet can be kept closed in the refrigerator for half an hour before putting the wipe in position for a few minutes.

• Complex of plant extracts Emollient and cleansing action. Helps to maintain a good periocular cleanliness. • Hyaluronic acid Humectant and moisturizing action.

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Nefrys

CAT

To maintain a healthy upper urinary tract.

Package sizes and dose forms Nefrys® 100 ml with dosing syringe

Protects the kidney against toxic substances.

• With PEA-um + Silymarin (patented combination). Physiological action. • Contains no meat or meat derivatives.

Reduces oxidative stress.

• Safe also for prolonged administration, it presents no contraindications or side effects.

What it contains

How to use

• PEA-um (ultra-micronized palmitoylethanolamide) Active form of PEA. Maintains the correct reactivity of kidney mast cells.

Administer twice a day the quantity indicated in the table at mealtime. Shake the bottle well, insert the graduated syringe in the hole and draw the preselected quantity indicated in the table. Administer the contents of the syringe directly into the animal’s mouth or mix it with the food.

• Silymarin Flavonoid extract from Milk thistle (Silybum marianum) with an antioxidant function. • Chitosan and Calcium carbonate Help to maintain the intestinal physiological levels of phosphate and products of protein digestion (e.g., nitrogenous waste).

Body weight (kg) 0-4 5-8 9 - 12 13 - 16 17 - 20 21 - 24 25 - 28 29 - 32 33 - 39 ≥ 40

URINARY TRACT

Helps to maintain the physiological balance of the kidney.

Its unique features

ml* 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5

* To be administered twice a day

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Urys

For a healthy lower urinary tract.

Package sizes and dose forms Urys® Liquid 60 ml with dosing syringe Urys® Caps 30 skittle capsules

Promotes the barrier function of the urothelium (inner lining of the lower urinary tract).

• With PGA-m (ALIA effect). Physiological action. • Can be used for long periods of time (safe). • Two dose forms for easy administration (squeeze skittle capsules and liquid).

Protects the lower urinary tract from oxidative stress.

• Palatable and easy to administer to cats.

What it contains

How to use

• PGA-m (micronized palmitoyl-glucosamine) Reduces the reactivity of bladder mast cells. It releases glucosamine, a natural component of the protective layer of the bladder urothelium.

Administer the product at the daily quantity indicated in the table. CAPS: open the skittle capsule as illustrated in the drawing (1) and squeeze its contents into the animal’s mouth or mix it with its ration of food (2). Alternatively, the skittle capsules can be swallowed whole.

• Hesperidin Flavonoid extracted from bitter orange (Citrus aurantium) with a high antioxidant activity.

URINARY TRACT

Helps to maintain the physical balance of the bladder.

Its unique features

Body weight Caps/day (kg) 7 - 11 1 12 - 20 2

Body weight Caps/day (kg) 21 - 30 3 > 30 4

Body weight ml/day (kg) 11 - 12 2.5 13 - 15 3

Innovet supports

Fondazione Salute Animale (The Animal Health Foundation) Info at: www.fondazionesaluteanimale.it

member of

MB0295-01-2024

For more information, visit www.innovet.it/prodotti