Invest in Tuscany - Life Sciences - EN

Tuscany, for centuries in the future

Life Sciences

www.investintuscany.com

You know • How difficult it can be to count on specialist and reliable suppliers in the life sciences sector.

• How rare is a territory that can guarantee high knowhow, professionalism and highly specialized personnel.

• How crucial it is to find the right partner to develop new projects, new products and new technologies.

in Tuscany you can!

• Recruit young talents and experts in scientific and technical fields through an extensive network of academic, training facilities, and medical research centres. 2 Tuscan universities are among the top 200 in the world (QS World University - https://www. qs.com/rankings/), and these are flanked by research institutes actively engaged in knowledge transfer to promote innovation.

• Run into university spin-off projects for technology transfer.

• Compete in international markets working with highly innovative companies, in some cases national and global leaders and large multinationals.

• Count on a health system first in Italy and among the most efficient in the world in terms of service and health care and specialized services on complex cases.

Since • In Tuscany there is one of the 15 best bio-incubation platforms in Europe (“Toscana Life Sciences/TLS Bio Incubator”, ranking of Labiotech - https://www. labiotech.eu/tops/biotech-incubators-europe/).

• 2021 is the year of the launch of Tuscany Pharma Valley, the Italian automatic logistics platform with high technological integration specifically conceived and designed to serve the pharmaceutical sector.

120,000 square metres for handling, transport, storage and international distribution, import and export of medicines and raw materials.

• Tuscany’s high vertical specialization in immunology/ vaccines, oncology, cardiovascular, bio-robotics and neuroscience, translates into an articulated and widespread system consisting of 32 research centres and 37,000 square metres of dedicated laboratories.

• The dynamic and diversified regional economic environment, the high quality of life and the competitive cost of leased facilities make Tuscany one of the most favourable and convenient places to start a new business.

excellence grows up Since Tuscany is ranked the fourth region of Europe of the Future 2020/2021 for its attractive potential (Financial Times, February 2020), and it is one of the natural places of settlement of new initiatives and productive activities in the sector from all over the world.

A highly specialized landscape that counts important industrial, service and technological presences to constitute a specialized platform of global level, at the service of the most diversified economic segments.

ABIOGEN

ESAOTE

LONZA

EXOSOMICS

ABOCA

EUKEDOS

MENARINI

CODIFI

BIOMÉRIEUX

EXTERNAUTICS

COFARDIS

FAREVA

MALESCI ISTITUTO DE ANGELI

MOLTENI

FARMIGEA

MSD

DEDALUS

FIAB

OTSUKA

DIESSE

F.I.R.M.A. S.P.A.

PHARMANUTRA

DUPONT

FRESENIUS KABI

PHILOGEN

EBNEURO

GRIFOLS

SARTORIUS STEDIM

EDOS

GSK

TAKEDA

ELANCO

KEDRION

CSL

EL.EN. ENDOTICS

SEQUIRUS

DEKA

SHIRE BAXTER

LA VILLA

TOSCANA BIOMARKERS

LILLY

WINMEDICAL

in a land where The high concentration of production and research settlements guarantees a favourable context to inclusion in value chains and activation of partnerships between companies. Tuscany is studded with a widespread network of competence centres, production plants and advanced research and development facilities, some of them among the first in the world. All at the service of entrepreneurs and operators active in the sector, from whatever country they come from, whatever their size is, regardless of their level of maturation: from start-up to the most articulated multinational. A widespread and extensive distribution with some points of natural concentration where affinities, complementarity and integration of the various subjects, including service networks, have given rise to specific clusters.

From the point of view of competitive advantages, in all the specialty segments of Life Sciences, Tuscany is well above the European average, for example in Biomedical devices (514%), Orthotics and Prosthetics (742%), bioinformatics (379%), qualifying as a territory of extreme interest and favour to start innovative entrepreneurial initiatives.

ÂŤRevealed Comparative Advantage IndexÂť (Europa = 1) Biomedical tools and devices

5,14 e-health

2,09 Orthoses, prosthesis and implantable and simulation

7,42 Bioinformatics, in silico modelling and simulation

3,79 Clinical trials for new drugs and therapies

Dynamic companies of the production chain

3,34 Medical robotics, biomedical instruments

3,30 Assistive technologies for the disabled

3,19

All the companies in the production chain

first-class standards The main economic indicators confirm the competitive positioning of the territory, both in the national and international context. Making it one of the best European and global destinations to invest in research and development and in service and production activities. With all the advantage of settling in one of the most evocative places in the world.

Subsector detail

150 € B

Biotech-Pharma

Distribution/Trade

Healthcare

Medtech

Tuscany

Turnover 20% 5%

8%

12.7 € B

67%

Biotech-Pharma contributes to Life Sciences Turnover by 67% and together with distribution/ Trade, they contribute to almost 90% of the Sector Turnover.

12,7 € B

3,1

€ B Export

Companies 17% 17% 14%

5,800

52%

Biotech-Pharma & Distribution/ Trade are more concentrated, Healthcare & Medtech are more fragmentend with smaller companies.

suit your needs.

The Tuscan economic fabric can meet all the different investment and expansion needs of your business, providing sectoral expertise and dedicated infrastructures for the functions and areas of operation and specialties that most affect your organization’s investment objectives:

Call Centres & Technical Support Centres At the head of the entire Tuscan system of Life Sciences is the Tuscany Life Sciences Foundation, which works to facilitate the process of start-ups in the field of biotechnology applied to human health. It supports research in the field of orphan diseases, and manages technology transfer activities in the field of biomedical and research enhancement through national and international networking activities. From a technical point of view, it is the main information and guiding hub for the entire Tuscan system in this area.

• Tuscany Life Sciences www.toscanalifesciences.org

Research & Development Tuscany’s high vertical specialization in immunology/ vaccines, oncology, cardiovascular, bio-robotics and neuroscience translates into an articulated and widespread system consisting of 32 research centres and 37,000 square metres of dedicated laboratories, among which stand out:

• University of Florence www.dss.unifi.it

• Scuola Superiore Sant’Anna of Pisa www.santannapisa.it/it/istituto/scienze-della-vita/ istituto-di-scienze-della-vita

• Vita Foundation - ITS for New Life Technologies www.itsvita.it

Business Services Among the top-level services for companies in the sector, the Distretto Toscano Scienze della Vita and the Bioincubatore Tuscany Life Sciences operate in the transfer of innovation and scientific development and in the provision of services to support business and product development.

• Distretto Toscano Scienze della Vita www.scienzedellavita.it (more than 190 member companies, 5.5 billion of total turnover, 32 research infrastructures, 14 research organizations, 6 service centers. It is the regional cluster that brings together all public and private entities operating in the fields of biotechnology, pharmaceuticals, medical devices, nutraceuticals, cosmeceuticals and ICT applied to life sciences). The Cluster was created in 2011 thanks to the Tuscany Region with the aim of contributing to the growth of the Region’s competitiveness by planning integrated research and development activities around innovative projects and creating a network of excellence of companies in the field of research and technology transfer.

• Bioincubatore Tuscany Life Sciences www.toscanalifesciences.org is equipped to offer spaces and services for growing companies; the incubator operates in particular in the fields: biotech, diagnostic, medical devices, nutraceuticals and cosmeceuticals, new technologies applied to life sciences. The incubator supports non-profit companies and research groups at every stage of their development and is a benchmark for companies that need to realize their business ideas.

Logistics In 2021 will open, around the “Amerigo Vespucci Interporto” area, the Toscana Pharma Valley, an automatic Italian logistics platform with high technological integration specifically conceived and designed to serve the pharmaceutical sector.

120,000 square meters for the handling, transport, storage and international distribution, import and export of medicines and raw materials. Unique at a national level and among the few at a European level, it will make the establishment in Tuscany of specialized activities in the Life Sciences even more fluid and convenient. It will be fully integrated with a dense network of iron and rubber infrastructure for fluid logistics of people and products, thanks to which Tuscany ranks among the main logistical nodes of the country. In addition, the presence of three seaports, including the Livorno platform (one of the best performing and most integrated at European level), facilitates connections with the rest of the world and with the rest of Europe. In particular, it allows a substantial saving of time to and from South East Asia and immediate access the main European corridors.

Motorways

Rail Infrastructure

Motorways provide good transports links througout Italy:

An execellent, rapid rail link system guaranteeing:

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•

•

2 jey north-south motorway axes (the A1-E35 Milano-Roma and the A12-E80 Genova-Livorno)

50 daily links between Florence and Rome (1 hour 31 min)

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24 daily links between Florence and Milan (1 hour 35 min)

1 east-west motorway (A11-E76-Viareggio-Pistoia)

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17 daily links between Florence and Venice (2 hour 5 min)

Ports 2 commercial ports in Livorno (7th Italian port, 6th for cointaner traffic serving all the major ports in the world) and Piobino, in close proximity to other major Italian ports.

Airports 2 major international airports, Pisa and Florence, for passengers and freight, with numerous daily flights to major italian and Europen cities.

Manufacturing The region has a consolidated tradition in the scientific field with a strong focus on research and development that, over the years, has given rise to leading companies at national and international level in the Biotech-pharma, Bio-Robotics and Medtech sectors. Tuscany has always been a land of research and innovation. Ideal for those who wish to carry out revolutionary projects and conduct experiments in their core business. The Tuscany Region has constituted the Distretto Tecnologico delle Scienze della Vita with the intent of creating opportunities and development, bringing together all public and private partners who are active in the fields of biotechnology, pharmaceuticals, medical devices, nutritional products, cosmeceuticals and ICT applied to life sciences.

Pharma Valley key points and goals:

2

1

INBOUND LOGISTICS (Raw materials, packaging)

3

6 5

4

OUTBOUND LOGISTICS (Finished Product) EXPORT CENTER DISTRIBUTION CENTER (Regional/National) IMPORT & TRANSIT POINT DIGITAL HUB

• Creating new space for production • Synergies costs from centralization • Serialization and product traceability • Regulatory obligation (GMP/GDP) • Last mile supervision • E-commerce/Home delivery • Global networking (regulatory/custom) • Leadership in innovation processes

You know, in Tuscany you can!

Since excellence grows up in a land where first-class standards suit your needs.

Tuscany, for centuries in the future.

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