RISE Newsletter - Spring 2023

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In This Issue + Product Champions + Upcoming Promos + Big News for All Select Sires Team Membrs + Mycotoxin Reporting + Global Agrarian – Opening Asia + Mycotoxin Myths RISE
globe!the
Agrarian Solutions visits Dubai – Green Fields Feed for Industries (pictured left to right) Dr. Mohamed Ramadan – IFT Dubai, Nic Bradley, Mark Lantz, Eng. Ahmed Hassan Al Manqatiny – Green Fields for Feed Industries, Dr. John Doerr
around
m

A Letter from Agrarian Solutions® President

Greetings from Agrarian! We are already wrapping up the 1st quarter of 2023 and the days seem to fly by.  Optimism is running high as we are having one of the strongest starts to the year that we have ever had.   We were also pleased to release our new BioFresh® Microbial Gel and Convert™ BIG Calf Powder.  We are already seeing significant sales and very positive reports from the field.

We are experiencing some significant market penetration with our core products as people continue to see not only the benefits when mycotoxins are present, but the overall health and improvement to the immune system through a healthier gut.  These products are performing well with dairy cows in the U.S. as well as swine in Asia, and poultry in the Middle East.  Agrarian product programs are improving the health and performance of camels in the UAE, dairy cows in Quebec, and chickens in Egypt…and that is just to mention a few.

In addition to our high-performing family of products powered by Agrarian’s L-form technology, we are exploring some new products that could provide significant benefits to the end-user.  All this is great news, but what sets Agrarian apart is the relationships we have with our co-workers, customers, and suppliers all over the world.  It is the fuel that drives our engine, and it is what makes us want to come to work every day!

Those of us at Agrarian are always eager to hear from our partners and colleagues with suggestions and ideas.  This is why we exist…it is our desire to see others succeed.  We are excited about the future with you, and truly believe that our greatest days are just ahead. Thank you for being on the Agrarian team!

2 Agrarian Solutions® RISE Newsletter | Spring 2023

Agrarian Solutions® Team & Staff Updates

MARK CARPENTER Executive Vice President and General Manager

We are extremely pleased to welcome Mark Carpenter to the Agrarian team as Executive Vice President and General Manager. Mark brings a wealth of talent and experience to the team. Many of you know Mark and have witnessed his ongoing leadership with Premier Select Sires. Mark brings a strong vision and the strategic acumen that will be instrumental in reaching our future goals. Mark is a great fit and a welcome addition to the Agrarian team.

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Mark Lantz President Rob Hamaker Vice President, Sales & Marketing Mark Carpenter Executive Vice President, General Manager John Doerr, Ph.D., PAS, Dpl. ACAP Vice President, Science & Technology Chad Christensen Regional Sales Manager Midwest Plains Region Dan Hoying Regional Sales Manager Midwest Region Nic Bradley Director of Operations Scott Zehr Business Development Manager Kurt Marquardt Sales Representative East Asia Mary Taylor Administrative Assistant Larry Roth,, Ph.D., PAS Vice President of Nutrition Jamie Peth Regional Sales Manager West Coast Kelbi Veenstra Office Manager Kelly Bristle ALL IN Community Manger

Introducing Two New Members of the Agrarian Solutions Program:

These new members of the team are designed with an emphasis on boosting ruminal fermentation and whole digestive tract health. Not all microbial counts are equal, and these products feature 9 billion CFU of beneficial bacteria and yeast per Microbial Bolus or 15 ml Microbial Gel. Both products also utilize eggbased specialized proteins and vitamins to dominate digestive pathogens and enhance immune function.

The trusted and long-proven BioFresh® Bolus is now transformed into the BioFresh® Microbial Bolus!

Faster bounce-back for fresh cows

Restore feed intake and ruminal fermentation for off-feed cows

Enhance immune function for challenged and high SCC cows

Dairy and beef producers are reporting great results with the newly introduced BioFresh Microbial Gel and cite these benefits:

Faster return to feed intake after off-feed periods

Reduced health treatments needed and fewer re-treats needed

Ideally designed for

• Newly weaned cattle

• Cows at calving

• Assist with health treatments

“We gate cut some sale-barn calves upon arrival at our feedlot and gave one pen the BioFresh® Microbial Gel at initial processing. The Gel pen had 40% fewer pulls, lower medication costs and took off on feed faster than the control pen.”

4 Agrarian Solutions® RISE Newsletter | Spring 2023
the Excitement! m
Join
New
m Contact your Agrarian representative for more information on these key components of the Agrarian Program.
& Enhanced
5 Product Champions 1 COBA Select Sires 2 Premier Select Sires 3 CentralStar Select Sires 4 Minnesota Select Sires 5 Select Sires MidAmerica 6 All West Select Sires DTX™ Concentrate Sales 1/1/23 – 3/31/23 Product #1025 1 CentralStar Cooperative 2 All West Select Sires 3 Premier Select Sires 4 COBA Select Sires 5 Minnesota Select Sires BioFresh® Microbial Bolus Sales 1/1/23 – 3/31/23 Product #11011-11012 1 Premier Select Sires 2 COBA Select Sires 3 Select Sires MidAmerica 4 Minnesota Select Sires 5 CentralStar Cooperative Ca3 BioFresh® Sales 1/1/23 – 3/31/23 Product #11040 1 Premier Select Sires 2 CentralStar Cooperative 3 Minnesota Select Sires 4 All West Select Sires 5 COBA Select Sires 6 Select Sires MidAmerica Convert™ BIG Calf Powder Sales 1/1/23 – 3/31/23 Product #3600-3625 1 Premier Select Sires 2 Select Sires MidAmerica 3 Minnesota Select Sires 4 CentralStar Cooperative 5 COBA Select Sires 6 All West Select Sires Convert™ Day-One Calf Gel Sales 1/1/23 – 3/31/23 Product #11004-11005

Upcoming Promotion

May 2023

June/July 2023

August 2023

6 Agrarian Solutions® RISE Newsletter | Spring 2023

Success is Subjective

“Success isn’t always about greatness. It’s about consistency. Consistent hard work leads to success. Greatness will follow.” – Dwayne “The Rock” Johnson

This quote by “The Rock” very much encapsulates what All In is all about. All In is about showing up each week for the men and women across the U.S. and Canada that serve the livestock community. In April of ’23, we will be celebrating two full years of the All In program. That’s two full years of providing an hour-long platform where people who want to grow personally and professionally can have meaningful dialogue. The topics range from leadership and sales strategy to product discussions, and include workshops to improve communication and selling skills.

There are so many things that go into a commitment like this that people do not see, so I wanted to take a moment to thank some people for their hard work! Jamie Peth – Jamie is the mastermind behind the program. She has taught us how to do this thing each week. When others get down and question things, Jamie is the one who continually says, “Just keep showing up. You will make an impact.” Rob Hamaker – For having the courage to try something different and implementing the right team to make it happen! Kelly Bristle – Kelly has become the engine that drives this program. Kelly is the ultimate team captain. She’s organized and finds creative ways to help others who are not nearly as organized. Ah-hem…Thanks, Kelly. Nic Bradley – For helping us establish goals and a long-term vision for this program. Take a minute to send them a note and thank them if All In has made a difference for you!

Throughout the last two years, we have heard from numerous people that we have made a positive impact on their career, perspective on the industry, and even their lives. Honestly, that is the very definition of Success for the All In program. My personal goal is that we make a difference for at least one person every week when we go live with the call. If you are one of the participants, thank you! If you have been on the fence about joining the live Zoom call, give it a try. Challenge yourself to be successful. We would love the opportunity to help you!

All In, is a live Zoom call that is simulcast into the private Facebook group: All In – Where Champions Connect. We start our calls at 4pm ET every Monday. You can join the Facebook group by clicking this link: https://www.facebook.com/groups/ wherechampionsconnect You can watch all of the replays and find any Agrarian resource you need by clicking this link: allin.agrarianhub.com

You can join the Zoom calls live by clicking this link each week: https://us06web.zoom.us/j/83810760916

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Scan this code to join our ALL IN community
Scott Zehr Business Development Manager

Agrarian University

District Sales Manager - COBA Select Sires

“Since Agrarian University, I have gained a significant amount of confidence in my discovery and follow-up after the sales. I have put another 1300 cows on DTX using the skills that I learned and retained/increased sales to several smaller herds that weren’t getting the desired results from DTX by discovering that their nutritionists had them on a lower level than recommended, so we increased to the full rate on those farms and saw a response.

Those results have impacted my life by making me feel like a more valued part of my customer’s operations as I build those relationships beyond genetics sales. It has caused some of those customers to ask for advice in other areas of their operations as well. It has been a nice boost for the paycheck as well.

I said yes to Agrarian University because I wanted to be more than just another genetics salesperson when I pull into a dairy or beef operation. I wanted to be able to add value to the genetics that I was selling in any way possible because coming from a dairy background I know that an animal won’t achieve its genetic potential if it faces challenges nutritionally or environmentally.”

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Big News for All Select Sires Team Members!

We are excited to announce the launch of our brand new training program specifically designed to help you develop your product knowledge and grow your personal product business as a Select Sires professional.

The Agrarian team has been working hard behind the scenes to create an experience like nothing else you will find in the industry. we have something amazing to show you.

We are going to give a few people reading this right now a major advantage to accelerate their product expertise and generate more sales without prospecting your face off.

And I promise, we created this to literally knock your socks off.

But here’s the problem:

This will only be available for a limited number of people.

Why?

Because when you hear the real-world value and personal guidance our team is investing to help provide these few people the foundation they need to create a massively lucrative product business…

… you will immediately understand why it’s limited by how much personal time, support, and money we’ll be investing to make this a high-impact, transformational experience.

Here are just a few of the things you can expect to learn in this training program:

• Get clear on your goals and earning potential by adding consistent product business to your sales arsenal

• Learn how to confidently identify opportunities to sell products on the farm that always puts the customer first

• Get real time support for actual on-farm challenges specific to your customers

• Get connected with a group of SS pros just as committed as you to hit their sales targets

So here’s what to do next:

If you’re interested in hearing more, scan this QR code with your phone and enter your best contact information. We’ll personally reach out so we can schedule a 15-minute call to see if this solution is a good fit for you.

You can also email me at:

jpeth@agrsol.com

Put “Agrarian University” in the subject line.

Since this is only for a limited number of people that our team will be closely working with, I’d love to introduce myself, answer all your questions and make sure you’re a good match for our next group.

And because these calls are on a “first come, first serve” basis, everybody who signs up first will get the foremost opportunity to take a look at this program.

... and if we’re a good match by the end of the call…

… you’ll also get a priority invite before anybody else to lock in your spot with the rest of this exclusive group of elite professionals.

So, to get the details today, follow these directions exactly:

#1- Scan the QR code or send an email as noted above

#2- Enter you best contact information

#3- Look for an email directly from us with the subject: [Agrarian University] Call

Don’t delay! We have a serious vision and strategy to share with you that worked incredibly well for those that have already created a highly lucrative and efficient product business.

If you are ready to be first in line to hear about all the details, follow the steps above & see for yourself.

I truly believe you’re going to love it, especially when you see who else will be joining us.

Chat soon.

Not sure if this is right for you, but curious? Scan the code and we will chat regardless of your job title!

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Jamie Peth Regional Sales Manager - West Coast

HUB Easy to Navigate m

Agrarian Solutions comprehensive online library of resources designed to get you what you need to better serve your customers as quickly as possible.

10 Agrarian Solutions® RISE Newsletter | Spring 2023

There’s one resource we simply cannot get back…TIME!

Which is why the Agrarian team is thrilled to announce the launch of our incredible Agrarian Hub, a comprehensive online library of resources designed to get you what you need to better serve your customers as quickly as possible.

Our team has worked tirelessly to create a platform that provides the most comprehensive collection of tools, information, and resources available. Whether you’re looking to expand your knowledge, get fliers to give out to customers, or simply stay ahead of the curve, we’ve got you covered.

The Agrarian Hub offers a wealth of features, including:

• A vast library of training videos and marketing material to help you sell products confidently

• Tools and articles to keep you up to speed with the most relevant industry research

• Access to expert-led webinars and workshop replays designed to help you grow your skills and knowledge

• Access to join a vibrant community with like-minded professionals where you can connect, share ideas, and collaborate on projects

With Agrarian Hub access, you won’t have to spend countless hours sorting through the answers to determine what’s true. Guaranteed to have the most up-to-date content, the Agrarian Hub is a searchable, easy-to-access online source. You can find anything you are looking for related to the front end of the cow, products made by Agrarian Solutions, and some things you didn’t even know existed.

Along with ALL IN replays, the Agrarian HUB gives you access to the most current:

Product Tech Data Sheets (with all the key information you want like ingredients, dosage rates, etc)

Research studies

Articles

Sales flyers

Producer results

Sales training

Much more

No one has an infinite amount of time, so using the time you have to maximize what you want to accomplish is paramount. The Agrarian Hub is guaranteed to help you use your time more efficiently, giving you the opportunity to further develop your product expertise to better serve your customers, while expanding your earning potential.

Scan this QR code below or visit agrarianhub.com to get registered TODAY!

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Comparisons of Various Products for Binding Efficiency of Mycotoxins, Amino Acids and Vitamins

Several products are marketed for their ability to bind mycotoxins and thereby protect food-producing animals from the harmful effects of mycotoxins. Recent research has raised concerns about the inability of these products to adequately protect animals by sequestering mycotoxins, and may in fact reduce the availability of amino acids and vitamins.

Kihal et al (2022) conducted a meta-analysis of 68 peer-reviewed research studies to determine the percentage mycotoxin adsorption by various mycotoxin binder products (MTB). The analysis found that mycotoxin adsorption is highly variable, with aflatoxin being the highest and deoxynivalenol being the least. In addition, activated carbon (charcoal) was the most effective MTB across mycotoxin type; however, considerable variation in pore size exists due to source and processing.

Earlier research (Kihal et al., 2020) evaluated adsorption by the MTB for vitamins and amino acids. When the water- and fatsoluble vitamins D and E were incubated together, the MTB adsorption average 35% for the water-soluble vitamins and 37.2% of the vitamin E, while minimal vitamin D was bound. The researchers incubated the amino acids lysine, methionine, threonine and tryptophan together with the MTB and found that 19% of the amino acids were bound.

Summary

Common MTB are ineffective for adsorption of mycotoxins, except aflatoxin; further, the MTB did bind water-soluble vitamins and vitamin E, as well as amino acids. Rations including common MTB should be adjusted for reduced vitamin and amino acid availability.

1Kihal et al (2022). J. Anim. Sci. 100:1-14.

2Kihal et al (2020). J. Dairy Sci. 103:3125-3132.

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Table 1. In vitro Efficacy of Mycotoxin Binding by Various Mycotoxin Binder Types1

Mycotoxin Summary Results

Mycotoxin summary results for October 1, 2022 through March 31, 2023 are displayed in figures 1 and 2 for TMR and corn silage samples, respectively. Generally, Eastern States, with higher rainfall patterns, posted higher mycotoxin levels than the Plains States experiencing drier conditions or drought.

Ohio’s TMR assay results were most problematic with a combination of elevated DON and zearalenone readings to affect both digestion/nutrient absorption and reproductive success. Interestingly, Ohio’s corn silage zearalenone levels were not that concerning, suggesting that by-products being fed could be significant zearalenone contributors to the Ohio TMR values. Conversely, Michigan TMR mycotoxin levels were somewhat lower than what might be predicted from the state’s corn silage assays.

High fumonisin corn silages values were observed along the Eastern Seaboard from South Carolina through North Carolina, Virginia and into Maryland and Pennsylvania. Fortunately, other feed ingredients must have been relatively low in fumonisin to create the safe levels seen in the TMR samples.

I encourage you to participate in the Agrarian mycotoxin testing program. We are emphasizing recording crop year for the corn silage samples to identify year to year changes, as well as variability through the year. In addition, please consider the value of monthly monitoring of TMR and corn silage for mycotoxin variation. Proactive sampling may help to identify challenges before escalating. Contact your Agrarian representative for the latest on mycotoxin evaluation.

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mycotoxin Report m OCTOBER 1, 2022 - MARCH 31, 2023
PAGES 13-17

nd = none detected = low = medium = high

ppb = parts per billion

14 Agrarian Solutions® RISE Newsletter | Spring 2023 nd nd nd nd nd nd nd 250 nd nd nd nd nd nd nd nd nd 97 State Zearalenone T-2 Toxin Average START DATE October 1, 2022 | END DATE March 31, 2023 NO. OF SAMPLES 277 DON Average 1225 2030 265 1959 2005 420 370 1707 1755 3695 1619 1183 260 322 195 1128 270 1836
IL IN KS MD MI MN NE NY NC OH PA SD TN TX UT VA WA WI Fumonisins Average 867 nd 567 333 150 125 600 233 1550 150 397 100 nd 188 200 437 100 138 100 nd 110 85 180 83 nd 148 225 776 169 120 nd 140 nd 92 nd 139 TMR MYCOTOXIN VALUE STATE AVERAGES (all values in ppb) | OCTOBER 1, 2022 - MARCH 31, 2023
1 DON = DON + 3-Acetyl-DON + 15-Acetyl-DON; FUM = fumonisin B1 + fumonisin B2; T-2 = T-2 toxin + HT-2 Toxin

T-2 Toxin Average

15
ppb (parts per billion) <600 600-1500 1501+ nd
Fumonisins Average
ppb (parts per billion) <75 75-150 151+ nd DON
ppb (parts per billion) <300 300-1000 1001+ nd Zearalenone ppb (parts per billion) <100 100-300 301+ nd October 1, 2022 - March 31, 2023 State Averages (all values in ppb) TMR MYCOTOXIN VALUE STATE AVERAGES (all values in ppb) | OCTOBER 1, 2022 - MARCH 31, 2023
Average

nd = none detected = low = medium = high ppb = parts per billion

16 Agrarian Solutions® RISE Newsletter | Spring 2023 START DATE October 1, 2022 | END DATE March 31, 2023 NO. OF SAMPLES 188
CORN SILAGE VALUE STATE AVERAGES (all values in ppb) | OCTOBER 1, 2022 - MARCH 31, 2023
nd nd nd nd nd nd nd nd nd 190 nd nd nd 310 nd 305 nd nd nd nd 70 380 State Zearalenone T-2 Toxin Average DON Average nd nd 550 nd 440 120 nd 620 4345 1543 270 nd nd 2072 2909 1895 2075 105 nd nd 3821 3377 AR ID IL IN IA KS LA MD MI MN MO NE NM NY NC OH PA SC SD TN VA WI Fumonisins Average 6400 nd 300 nd 100 nd nd 900 nd 185 nd nd nd 200 2340 397 1232 1200 nd 2400 1107 360 nd nd nd nd nd nd nd 60 2195 207 nd nd nd 135 575 178 284 nd nd nd 238 285
1 DON = DON + 3-Acetyl-DON + 15-Acetyl-DON; FUM = fumonisin B1 + fumonisin B2; T-2 = T-2 toxin + HT-2 Toxin

T-2 Toxin Average

17 Fumonisins
ppb (parts per billion) <600 600-1500 1501+ nd
Average
ppb (parts per billion) <75 75-150 151+ nd DON
ppb (parts per billion) <300 300-1000 1001+ nd Zearalenone ppb (parts per billion) <100 100-300 301+ nd October 1, 2022 - March 31, 2023 State Averages (all values in ppb) CORN SILAGE VALUE STATE AVERAGES (all values in ppb) | OCTOBER 1, 2022 - MARCH 31, 2023
Average

aroundglobe!the m

18 Agrarian Solutions® RISE Newsletter | Spring 2023
Thailand - Dr. John Doerr, Ms. Mon - Sinotrade Thailand - Ms. Mon – Sinotrade, Dr. John Doerr, Miss Subaidah Egypt Pyramids IFT Egypt - Aya Fatouh, Soha Saied, Heba Amin, Nic Bradley, Mark Lantz Dubai – Green Fields Feed for Industries Dr. Mohamed Ramadan – IFT Dubai, Nic Bradley, Mark Lantz, Eng. Ahmed Hassan Al Manqatiny –Green Fields for Feed Industries, Dr. John Doerr Thailand - Dairyland Dairy Thailand - Prayoon – Sinotrade, Dr. John Doerr, Ms. Mon – Sinotrade, Miss Subaidah Egypt - Value Vet team

SYNER-TOX and The Ship of The Desert

The camel occupies a distinguished place in the heritage of the Arabs, a position dating back nearly 1800 years. We raise camels as companions and for meat, milk, transportation, and racing. So many of us depended on their ability to live in the desert and adapt to its harsh nature… intense heat, scarcity of water, and scorching sun. In the United Arab Emirates, the population of camels today is approximately 450,000.

For this reason, the camel has a special place in the Middle East and needs special medical care from birth and during its 40-year life span.

SYNER-TOX has been used in camels in the gulf region for more than a decade now with a significant impact on the camel’s health, not only with mycotoxins but especially with blood parasite/bacterial infections as there can be high occurrence of such blood infections in local camels caused by Anaplasma (bacterial), Theileria (parasitic), Trypanosoma (parasitic), and Babesia (parasitic). The diseases are characterized by fever

and intravascular hemolysis leading to progressive anemia, hemoglobinuria, and jaundice, as well as ‘off feed’, and may result in death.

The elevated liver enzymes, especially AST (aspartate aminotransferase), are very high which indicates liver damage not only from blood parasites but also from excessive drug detoxifications and mycotoxins. Using SYNER-TOX as a supportive treatment for successive three to five days with an oral dose twice daily of 60 – 75 ml diluted in 2 Liters of water showed remarkable improvement in reducing AST back to normal protecting the camel’s liver from damage and potential death.

SYNER-TOX now is the main supportive treatment for camels especially in liver disease having gained full trust of owners based on the liver recovery and health vitality of camels after treatment with it.

Syner-Tox is a liquid product added to drinking water. Syner-Tox uses Agrarian Solutions’ proprietary L-Form technology found in Select BioCycle and Select DTX.

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Global Agrarian – Opening Asia

Asian markets have been a goal for Agrarian. There, swine are a major production species and a number of controlled research projects have been completed to address concerns in Thailand and other SE Asia countries for this species. Let me share just a few highlights of that activity.

Beginning with a very small trial at Chulalongkorn University in Bangkok, investigations progressed onto large commercial swine operations that offered research-capable units. Several studies were completed with sows, the latest involving 250 sows divided between control (CON) and NDC (Nutrisound Dry Concentrate, our primary mycotoxin mitigating feed additive). Health, reproductive efficiency, litter size, livability of offspring, etc. were all favorably improved by NDC. But to give just one prime result that has implications for other lactating animals, here is a summary of metrics tested on colostrum:

abc Values in a row with different superscripts are significantly different (P<0.05)

While volatile fatty acids have great impact, butyrate is recognized for its positive influence on balancing the gut microbiome to improve over-all health of animals. Many companies offer products specifically to increase butyrate production! In this study, NDC outperformed the CON pigs and also the antibiotic and enzyme treatments. Similarly, fecal E. coli was reduced by nearly 3 log cycles by NDC and the antibiotic. NDC was a direct and complete replacement for a now prohibited growth-promoting antibiotic and one of the enzymatic approaches to growth promotion!

As a result of this research, Agrarian Solutions is now shipping containers of NDC to Thailand to our distributor there, Sinotrade Technology Co., for use by the second largest feed mill in the region, Betagro, for swine. New inroads are being established with two other mills and trials are now underway for its use in dairy animals in that country.

** NDC highly significantly different from CON (P<0.01)

Similar results were obtained for lactose and non-fat solids in colostrum and for all colostrum IgG collections during the first 24 hours post-parturition. Piglets from NDC sows also surpassed Controls for gain, survival, and lowered shedding of Gram-negative bacteria. Our attention then turned to weanling pigs. The data below are from a study with 30 pigs/treatment and 4 treatments: CON, CLT (colistin sulfate [Polymyxin E], BLM (bromelain [a growth promoting enzyme]), and NDC. Again, I just share a short sample of our results.

¹ Dr. Dachrit Nilubol, a highly recognized swine virologist, served as the principal investigator in these trials.

20 Agrarian Solutions® RISE Newsletter | Spring 2023
Variable CON NDC Colostrum yield (kg) 8.6 10.5** Fat (%) 3.8 4.1** Protein (%) 11.2 12.8** IgG (mg/ml) Parturition 88.8 112.5** 6 hours post-Parturition 64.7 83.7** Variable CON CLT BLM NDC Butyric Acid (mmol/L) Week 2 55B 77AB 77AB 90A Week 4 83B 124AB 112AB 161A Fecal E. coli (log10cfu/g) Week 0 7.4A 7.2A 7.3A 7.3A Week 6 7.5A 4.7C 5.7B 4.7C Fat (%) 3.8 4.1** Protein (%) 11.2 12.8** IgG (mg/ml) Parturition 88.8 112.5** 6 hours post-Parturition 64.7 83.7** Variable CON CLT BLM NDC Butyric Acid (mmol/L) Week 2 55B 77AB 77AB 90A Week 4 83B 124AB 112AB 161A Fecal E. coli (log10cfu/g) Week 0 7.4A 7.2A 7.3A 7.3A Week 6 7.5A 4.7C 5.7B 4.7C

Hello, we are Agrarian Solutions® and we exist to help others succeed.

At Agrarian Solutions® we believe we exist to help others succeed. In each one of us there is a Champion’s heart. We want to come alongside you and help you R.I.S.E. to the occasion; whatever that may look like for you. Every day each one of us encounters an opportunity to help others by providing a

service, product, word of encouragement, or even a smile. Whether it’s the local banker we are working with, our product distributors, vendors, suppliers, or end users of our products, we want to help you RISE to the occasion. At Agrarian Solutions® We Help Champions Succeed!

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Mycotoxin Myths

As well-known as mycotoxins have become in animal agriculture, there are some recurring myths needing correction so a producer can make good choices when faced with a possible threat to the herd or flock:

Mycotoxin = aflatoxin. False Aflatoxins are just one kind of over 2000 known mycotoxins. Zero aflatoxin does not mean that there are no mycotoxins. A corollary is that when a test for 6 or so different mycotoxins is performed and the results are negative, the feed tested is ‘safe’. False. While we don’t see some of the odd mycotoxins very often, or if they are not part of the test panel, the animals may still be at high risk. For example, one called beauvericin has been known for over a decade, but little was known about its effects on domestic species. In a 2016 study, Schoevers [E. J. Schoevers, et al. (2016). Toxicity of beauvericin on porcine oocyte maturation and preimplantation embryo development. Repro. Toxicol. 65:159-69] reported that this toxin has serious impact on developing pig embryos shortly after fertilization of the ovum. At this time, we may not have similar studies for poultry or cattle, but the implication that they are also at risk is reasonable. Does your mycotoxin test include beauvericin?

Monogastrics absorb mycotoxins differently that ruminants True. But differences occur within each of those groups. Even within one type of animal (e.g., the dairy cow) different breeds have different susceptibilities to specific mycotoxins. And, within a single breed, there is considerable variation animal to animal on absorption and impact, usually dependent on health, environmental stress, genetics, etc. But, almost without exception, all animals do absorb mycotoxins in the same general region of the intestinal tract.

The rumen will detoxify key mycotoxins. False. Early research was performed in vitro with rumen fluid; some research confirms that a portion of deoxynivalenol (DON) is converted to a less toxic form. But zearalenone is converted in the rumen to an alternative form that is many times more estrogenic than the primary molecule. And while some research implied aflatoxins might be broken down, one must then explain how a conversion product of aflatoxin in the liver, aflatoxin M1, can show up in milk.

High levels of mycotoxins are needed to affect animals

False. First exposure may be acute...a sudden problem from a portion of one ingredient for a short time...or chronic...low to moderate levels over a long period of time. Each will impact the herd or flock. And, when there are multiple mycotoxins, low amounts generally produce the most noticeable synergistic effects.

If the toxin is below FDA levels, it’s okay. False. FDA’s primary mission is to protect humans from problems related to their food, and secondarily to protect animals from chemicals that may harm them or contaminate the milk, meat, or eggs they produce. But the line between what causes possible harm to a cow or pig and what impairs efficient production is not clear cut. Whether your Holstein produces 90 lbs of milk or 70 lbs of milk is not FDA’s concern.

22 Agrarian Solutions® RISE Newsletter | Spring 2023

R ELATIONAL we care about others

I NTEGRITY  a representation of your true character

S TRATEGIC growth with fiscal responsibility

E XCELLENCE  in all things

585 Shawnee Street Nappanee, IN 46550 Contact Us (574) 825-1224 office@agrsol.com agrariansolutions.com Follow Us On Social Media AgrarianSolutions AgrarianSolutions Agrsol RISE thenewall m

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