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A summary of the latest clinical studies Title: Study of the 0.1% Tretinoin Cream Vs Fractional Microneedling Radiofrequency Combination with Fractional CO2 Laser for the Treatment of Striae Alba in Indonesian Patients Authors: Listiawan M, et al. Published: Journal of Cosmetic and Laser Therapy, September 2021 Keywords: Laser, Radiofrequency, Striae Alba Abstract: Striae distensae (SD) is linear scar tissue in the dermis that arises from the stretching of the skin. There are two types of SD, striae rubrae and striae albae (SA) which is marked with a line hypopigmentation that cause a psychological problem, especially in the high skin types. The standard therapy is a 0.1% tretinoin cream, which takes a long time to reach the collagen, so needs invasive measures to reach these targets. This study compares 0.1% tretinoin cream with combination therapy of fractional microneedle radiofrequency (FMR) and fractional CO2 laser for SA. The number of subjects was 11 patients in each group with Fitzpatrick skin types IV or V. Biopsies were taken before and after therapy. The clinical changes in SA lesions in this study were represented by measurements of the length and width. The percentage of collagen in the area is the amount of collagen fibres with Masson’s trichrome staining. The clinical changes of lesions in the combination therapy decreased. The percentage change in collagen area in the combination therapy group had a higher increase. The side effect experienced by all combination group subjects was post inflammatory hyperpigmentation, and two subjects in 0.1% tretinoin cream group experienced irritation. Title: Superficial Lip Injections Utilising Cohesive Polydensified Matrix Hyaluronic Acid-Based Soft Tissue Fillers Authors: Goldie K, et al. Published: Journal of Drugs in Dermatology, September 2021 Keywords: Dermal filler, Injectables, Lip Improvement Abstract: A combination of optimal injection technique and dermal filler choice is key for improving lip architecture with natural and long-lasting results. Eligible patients underwent lip contouring and volumisation using a superficial direct tissue action technique. All injections were performed with CPM-HA lip fillers using a 30G needle and retrograde microthreading. Injected volume was 0.8-1.2 mL. High-resolution ultrasound imaging (US), 3D surface scanning, and Global Aesthetic Improvement Scale (GAIS) assessments were performed before, and one, three and six months post-injection to define the anatomy, positioning, longevity and patient satisfaction. 16 patients were injected. US measurements revealed an increased orbicularis oris muscle distance up to one-month post-injection, after which measurements returned to baseline values. This observation correlated with complete product integration into the surrounding tissue visualized by US at three months. An increased dry mucosa thickness remained at six months, and GAIS scores revealed 70% of patients continued to experience visible lip improvements. 3D analyses revealed increased total lip surface area at three months with increased Cupid’s bow distance, philtral height, and anterior upper lip projection. Superficial injection of CPM-HA fillers offers an effective and safe tool for improving lip architecture and volume.
Title: Association Between Exposure to Ambient Air Pollution and Occurrence of Inflammatory Acne in the Adult Population Authors: Haddad C, et al. Published: BMC Public Health, September 2021 Keywords: Acne, Pollution Abstracts: Acne vulgaris is one of the most prevalent skin diseases responsible for dermatological consultations. Outdoor air pollution is an external factor discussed to trigger inflammation of the skin. This study aimed to find a link between the exposure to ambient air pollution and inflammatory acne occurrence in the Lebanese adult population. A cross-sectional study was conducted, using an online questionnaire to collect the data from different Lebanese regions. The survey covered pollution exposure questions as well as several factors known to have a role on acne. 372 participants were included, aged 18 to 55. The results of a logistic regression taking the presence/absence of acne as the dependent variable, showed that female sex, younger age, using hydrating cream, working near a power plant vs not, having a severe NO2 exposure compared to none, a higher number of family members with acne or history of acne were significantly associated with higher odds of having acne, whereas having dry skin compared to normal was significantly associated with lower odds of having acne. The occurrence of inflammatory acne in Lebanese adults was found to be associated with exposure to high levels of NO2 and employment near a power plant known to emit CO2, CO, SO2, NO2 and PM. Our findings can serve as a first step towards implementing awareness of a skin care routine suitable for highly polluted areas. Title: Infraeyebrow Blepharoplasty Using Dynamic Suspension Technique Between Dermis-Fascia Flap and Frontalis in Upper Eyelid Lifting and Eyebrow Augmentation Authors: Cao Z, et al. Published: Journal of Craniofacial Surgery, September 2021 Keywords: Blepharoplasty, Eyebrow, Technique Abstract: Upper eyelid laxity affects facial aesthetics, and the eyebrow arch in the East Asian population is low. The authors developed infraeyebrow blepharoplasty using a dynamic suspension technique between the dermis-fascia flap and frontalis for upper eyelid lifting and eyebrow augmentation. A study was performed on 43 female patients with upper eyelid laxity from August 2015 to October 2019. The epidermis and superficial dermis of the infraeyebrow was removed from the surgical marking area with the deep dermis and fascia preserved. The eyebrow skin flap was separated from the frontalis surface, which exposed the area around the eyebrow arch. The preserved dermis-fascia flap was folded and suspended to frontalis in the superior margin of eyebrow arch. Follow-up was 25 months. All incisions healed well and were almost invisible. The eyebrow area improved with upper eyelid skin lift and eyebrow augmentation; 40 cases were “very satisfied” with their appearance. Three cases were “not very satisfied,” including one case with numbness in surgical area. Two cases had slight bilateral asymmetry of the upper eyelids. The dynamic suspension technique is worthy of clinical application because it can correct upper eyelid laxity, augment the low eyebrow arch, and obtain an invisible scar by reducing the incision tension.
Reproduced from Aesthetics | Volume 8/Issue 11 - October 2021
