MostCare Up Reminder card

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HEMODYNAMIC MANAGEMENT

up to the beat

THE

SERVING

MONITORING SYSTEM
YOUR THERAPEUTIC DECISION
MONITORING

Postoperative complications within 30 days occured for patients undergoing nonambulatory elective surgery1

Reduction of post operative morbidity with PCM technology2

A GOOD QUALITY SIGNAL IS ESSENTIAL

1/3 patients may suffer from underdamping/resonance of the arterial pressure waveform3

Underdamping/resonance phenomena has a substancial impact on CO measurements with pulse wave analysis4

Average worldwide cost of care for septic patient in ICU5

Most of these complications are paramount to hemodynamic troubles

ENHANCE YOUR THERAPEUTIC DECISION PROCESS, SECURE YOUR THERAPEUTIC IMPACT

Accurate arterial variables

Dynamic e-filter6,7,9 PRAM patented algorithm6 Supported by +70 studies8

Best quality/price ratio

No disposable Unlimited use Made in Europe

EASY 3-step process

Other unique features

Pedriatric use (>3kgs) Specific variables (e.g. CCE) HL7 compatible DO&CHECK function

After sales service

A COMPLEX REALITY…
IN A CHALLENGING ENVIRONMENT...
17% $37,000 54% > Check Connect Monitor >

ACCURATE ARTERIAL VARIABLES

PRAM

PRESSURE RECORDING ANALYTICAL METHOD

EASY 3-STEP PROCESS

As each patient is unique, PRAM constantly detects any morphological changes of the arterial waveform over time to adjust arterial impedance and reflect immediate changes of your patient hemodynamic status8

Comparison of CO estimated by PRAM (PRAM-CO) with CO measured by pulmonary artery thermodilution (PATD-CO). Prospective observational method comparison study (EJA 2020)

The PRAM method

(PATD)

Calibration or pre-estimates are not required, with MostCareUp you can monitor your patients accurately and quickly

CHECK MONITOR 12 1
CONNECT1
is as accurate as the clinical gold standard
for the CO calculation, thanks to the e-filter7 MostCareUp is your reliable and affordable hemodynamic monitoring solution supporting your therapeutic decisions Concordance rate >90% Percentage error <30% 456783 4 2 0 1] 1 ] 1.40 60% 45% 60% PATD-CO 45% PRAM-CO –60% –60% –45% –45% 30% Conc. = 0.917 30% –30% –30% 15% 15% –15% –15% 0% 0%

UNBEATABLE QUALITY/PRICE RATIO

• Unlimited patient use…

You are free to use your usual disposable an unlimited time : don’t change your habits, don’t be captive by dedicated disposables. MostCareUp guarantees the maximum flexibility and cost efficiency thanks to the various ways in which it can be used !

• …Or on demand application !

The on demand version of the monitor can be activated for a single use for periods of time to meet specific application needs.

250 PATIENTS

sp* OTHER sp* disposable use PRICE (150$/disposable)

minimally

The endless version allows an unlimited use of the system without additional cost. Disposable solution 5 times costlier after 5 years**

THE DYNAMIC OPTIMISATION OF ARTERIAL PRESSURE SIGNAL QUALITY

The quality of the blood pressure waveform is key to ensure accurate MAP and CO monitoring

AnalysisofthearterialpressurewaveformbyPRAM:ontheleftthepoints of instability (POi) indicated as Z(t)8,on the right a representation of the dicrotic pressure detected and measured at a frequency of 1000 Hz

Dicrotic pressure

With PRAM dicrotic notch is well identified, the 1000hz frequency allows the identification of POi to estimate the right impedance & calculate precisely MAP, CO and SVR8

MostCareUp FILTER ACTIVATION

BEFORE AFTER

The dynamic filter of MostCareUp automatically reduces the resonance phenoma to optimize arterial waveform and optimize the accuracy of the pulse contour method.

Asys Asys Z (t) SV = t P 1000 Hz
Z1 Z2 Z3 SYS DIA Z4 mmHg Time 160 60 F F Not active F Standard F Advanced
*sp=standardprice **costofusecomparisonbetweenanondedicateddisposalandadedicated disposable
invasive monitoring system
VYGON

THE

FUNCTION

VYGON’S UNIQUE VALUES

• Specific variable CCE

Cardiac Cycle Efficiency (CCE) is an exclusive variable which describes hemodynamic performance in terms of energy expenditure in the patient being monitored.

Relationship between between CCE and left ventricular ejection fraction (LVEF). CCE was estimated by pulse wave analysis and LVEF by echocardiography.The correlation coefficient is 0.88 (95 % CI 0.81–0.92, P\0.001).Black dots represent LVEF < 40 %,white dots LVEF ≥ 40 %.

CCE estimated by PCM and LVEF by echocardiography: CCE predict LVEF, accordingly showing a direct correlation. Low CCE indicate poor cardiac function and is considered an indication for echo11

Physiological range of CCE -0.2 ÷ 0.3 [units]

CCE as a «wake-up call» for an echocardiography

CCE as a simple surrogate marker of Ea/Ees

CCE expresses the ability of the cardio-vascular system to maintain homeostasis at different energetic levels10

-0,2 0,3
DO&CHECK
The DO&CHECK function is specifically designed to help you with hemodynamic monitoring variations following specific treatments (fluid challenge & passive leg raising, drugs administration, etc.) Your therapeutic decision is now tracked and supported by the DO&CHECK function. MostCareUp is the best monitor in your daily routine. 45° PLR 12.2012.30 12.40 12.50 PR CO CCE PPV 105 PR 3.8 CO 12% PPV 0.07 CCE (+23%) 120 PR 3.1 CO 18% PPV -0.19 CCE

A MONITOR ADAPTED TO ITS ENVIRONMENT

Connection & data side

WIFI: wireless connection to Hospital Information System supporting HL7 protocol

USB Port: quick data download

HDMI port: screen duplication

HDMI port: screen duplication LAN port: connection to Hospital Information System supporting Health Level 7 (HL7) messaging standard

Patient side

ABP Input to connect MostCare Up to the arterial blood pressure transducer

CVP Input for direct connection to CVP transducer and for real time values of Systemic Vascular Resistance

External module input

Input/Output for analogue connection to the bedside monitor

1st version launched in 2004

Minimum 2 Years warranty

~2% technical problem reported***

After Sales Service

Europe

For more information visit www.hemodynamic-management.vygon.com or contact your Vygon’s representative or via monitoring@vygon.com

ABOUT MOSTCAREUP & VYGON
***InternalVygonHQdata2022

1. Chang W. D, et al. Rehospitalizations following sepsis: common and costly. Crit Care Med. 2015;2085-2093

2. Michard F, et al. Perioperative goal-directed therapy with uncalibrated pulse contour methods: impact on fluid management and postoperative outcome British Journal of Anaesthesia, 2017;119 (1): 22–30

3. Romagnoli S, et al. Accuracy of invasive arterial pressure monitoring in cardiovascular patients: an observational study Critical Care 2014;18:644

4. Foti L, et al. The impact of arterial pressure waveform underdamping and resonance filters on cardiac output measurements with pulse wave analysis BJA 2022;03 024

5. Martin G, et al. sepsis severe sepsis and septic shock change in incidence pathogens and outcomes 2012;10(6): 701–706

6. Scolletta S, et al: Comparison between Doppler-echocardiography and uncalibrated pulse contour method for cardiac output measurement: a multicenter observational study. Crit Care Med44 2016; 1370-1379

7. Greiwe G, et al. Cardiac output estimation by pulse wave analysis using the pressure recording analytical method and intermittent pulmonary artery thermodilution Eur J Anaesthesiol 2020;37: 920–925

8. Romagnoli S, et al. The Pressure Recording Analytical Method (PRAM): Technical Concepts and Literature Review JCVA 2016;Sep 14

9. Foti L, et al. The impact of arterial pressure waveform underdamping and resonance filters on cardiac output measurements with pulse wave Analysis BJA 2022;03 024

10. Romano M, et al. Cardiac cycle efficiency: A new parameter able to fully evaluate the dynamic interplay of the cardiovascular system. Int J Cardiol 2012;155(2): 326-7

11. Scolletta S, et al. Assessment of left ventricular function by pulse wave analysis in critically ill patients. Intensive Care Med 2013;39: 1025-33

FOR FURTHER INFORMATION, PLEASE CONTACT: questions@vygon.com

The specification shown in this leaflet are for information only and are not, under any circumstances, of a contractual nature.

VYGON – 5, RUE ADELINE - 95440 ECOUEN - FRANCE

RECEPTION: +33 (0)1 39 92 63 63

SERVICE CLIENTS FRANCE: +33 (0)1 39 92 63 81

EXPORT CUSTOMER SERVICE: +33 (0)1 39 92 64 15

www.vygon.com

09/22DBMOST22639EV1

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