CCHRPP Researchers

Appendix C: Center for Collaborative HIV Research in Practice & Policy (CCHRPP) Researcher Information

OMB No. 0925-0001/0002 (Rev. 08/12 Approved Through 8/31/2015)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Birkhead, Guthrie S. eRA COMMONS USER NAME (credential, e.g., agency login): gsb002 POSITION TITLE: Emeritus Professor, Department of Epidemiology and Biostatistics, School of Public Health, University at Albany EDUCATION/TRAINING INSTITUTION AND LOCATION

DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

Princeton University, Princeton, NJ

AB

1975

Chemistry

Yale University School of Medicine, New Haven, Connecticut

MD

1979

Medicine

The Johns Hopkins University School of Hygiene & Public Health, Baltimore, Maryland

MPH

1985

Public Health

A. Personal Statement I am currently Emeritus Professor of Epidemiology and Biostatistics at the School of Public Health, University at Albany. Prior to September 2015, I worked at the New York State Department of Health (NYSDOH) for 27 years. From 1995 to 2006, I was the director of the AIDS Institute, the NYSDOH HIV program unit. I was heavily involved in programs to reduce mother-to-child HIV transmission, to increase HIV testing, to implement HIV named reporting, to implement expanded syringe access programs, and to address drug use as a risk factor for HIV/AIDS, among many other initiatives. I served as Deputy Commissioner and Director of the Office of Public Health from 2007 to 2015. As Deputy Commissioner, I provided overall direction and accountability for the AIDS Institute and for all departmental public health programs related to HIV/AIDS including epidemiology, surveillance, disease prevention and control, and public health laboratory. Prior to retiring from NYSDOH in 2015, I was Principal Investigator on numerous multidisciplinary grants including the State’s emerging infections and epidemiology and laboratory capacity grants from CDC. I have also numerous published papers in peer-reviewed literature on HIV/AIDS, as well as book chapters on a wide variety of topics including public health surveillance, immunizations, public health workforce and public health preparedness.

B. Positions and Honors Positions and Employment 1985-1987 Epidemic Intelligence Service Office, Centers of Disease Control, assigned to Epidemiology Division, Vermont Department of Health, Burlington, VT 1987-1988 Preventive Medicine Resident, Centers for Disease Control, assigned to Division of Surveillance and Epidemiologic Studies, Epidemiology Program Officer, Atlanta, GA 1988-1993 Director, General Communicable Disease Programs, New York State Department of Health (NYSDOH), Albany, NY 1993-1995 Director, Bureau of Communicable Disease Control, NYSDOH, Albany, NY 1995-2006 Director, AIDS Institute, NYSDOH, Albany, NY 2001-2006 Director, Center for Community Health, NYSDOH, Albany, NY 2006-2015 Deputy Commissioner, Office of Public Health, NYSDOH, Albany, NY 2015-present Professor of Epidemiology and Biostatistics, School of Public Health, University at Albany, Albany, NY

Other Experience and Professional Memberships Fellow American College of Preventive Medicine Member American Public Health Association Member/Past President, Council of State and Territorial Epidemiologists Member Editorial Board, Journal of Public Health Management and Practice Honors 2017 2015 2012 2011 2010 2008 2006 2005 2003

Doctor of Humane Letters (honorary). Albany College of Pharmacy and Health Sciences Noble J. Swearingen Award for Excellence in Public Health Administration. Association of State and Territorial Health Officials (ASTHO), Arlington, VA. APHA Public Health Practice Award. Presented to the New York State Department of Health Perinatal HIV Prevention Team, Guthrie Birkhead MD, MPH, team leader. American Public Health Association (APHA) Epidemiology Section. Annual APHA meeting, San Francisco, CA. Public Health Service Award. New York State Association of County Health Officials (NYSACHO), Albany, NY. President’s Award for Excellence in Research; In Recognition of Outstanding Performance and Significant Contributions to the University Community. University at Albany, Albany, NY. AMA Dr. Nathan Davis Award for Outstanding Government Service in the Category Outstanding Career Public Servant at the State Level. American Medical Association.

CSTE Pump Handle Award for Outstanding Achievement in the Field of Applied Epidemiology. Council of State and Territorial Epidemiologists, Atlanta, GA. Johns Hopkins University Society of Scholars inductee. The Johns Hopkins University.

Baltimore, MD. ASTHO Excellence in Public Health Award for Significant Contributions and Outstanding Leadership in Public Health. Association of State and Territorial Health Officials, Arlington,VA.

C. Contribution to Science My bibliography, which is available at: https://www.ncbi.nlm.nih.gov/myncbi/collections/bibliography/49333721/ Specific contributions to science include: HIV/AIDS: From 1995 to 2015, I lead efforts at the NYSDOH to develop the evidence base to support and evaluate major new HIV prevention initiatives in New York State to reduce mother-to-child transmission, to increase HIV testing, to address drug use, mental illness and homelessness as risk factors for HIV/AIDS, to increase access to sterile syringes and other harm reduction programs, and to improve care for persons living with HIV/AIDS. The results have been dramatic reductions in mother-to-child-transmission of HIV, improved access to HIV testing and access to sterile syringes, and reduced incidence of HIV/AIDS morbidity and mortality and new HIV infections.

1. Swain CA, Smith LC, Nash D, Pulver WP, Gordon D, Bian F, Miranda W, Anderson BJ, Chicoine J, Birkhead GS, McNutt LA. Postpartum Human Immunodeficiency Virus Care Among Women Diagnosed During Pregnancy. Obstet Gynecol. 2016 Jul;128(1):44-51 2. Swain CA, Smith LC, Nash D, Pulver WP, Lazariu V, Anderson BJ, Warren BL, Birkhead GS, McNutt LA. Postpartum Loss to HIV Care and HIV Viral Suppression among Previously Diagnosed HIVInfected Women with a Live Birth in New York State. PLoS One. 2016 Aug 11;11(8):e0160775 3. Birkhead GS. Guest Editor. New York State HIV Testing Law (Implementation Research). Journal of Acquired Immune Deficiency Syndromes. Volume 68, Supplement 1, January 1, 2015.

4. OĘźConnell DA, Martin EG, Cutler B, Birkhead GS. The Evolution of HIV Testing Requirements in New York State, 1989-2013. J Acquir Immune Defic Syndr. 2015 Jan 1;68 Suppl 1:S5-9 5. Birkhead GS, Pulver W, Warren B, Klein S, Parker M, Caggana M, Smith L. Progress in Prevention of Mother-to-Child Transmission of HIV in New York State: 1988-2008. Journal of Public Health Management and Practice 2010:16(6):481-491.

6. Birkhead GS, Klein S, Warren B, Candelas A, O’Connell D, Scully M, Cotroneo R, Cruz H. Program and Policy Interventions for Preventing Mother-to-Child Transmission of HIV in New York State. Journal of Public Health Management and Practice 2010:16(6):492-504.

7. Birkhead GS, Pulver W, Warren B, Hackel S, Rodriguez D, Smith L. Acquiring Human Immunodeficiency Virus During Pregnancy and Mother-to-Child Transmission in New York. Obstetrics & Gynecology 2010; 115(6):1247-1255. PMID: 20502297.

8. Tesoriero JM, Battles HB, Heavner K, Klein SJ, Kaufman E, Birkhead GS. Expanding Access to Sterile Syringes Through Pharmacies: Assessment of New York's Expanded Syringe Access Demonstration Program. Journal American Pharmacy Assoc. 2009; 49:407-416.

9. Klein SJ, Flanigan CA, Cooper JG, Holtgrave DR, Carrascal AF, Birkhead, GS. Position Paper – Wanted: An Effective Public Health Response to Hepatitis C Virus in the United States, J Public Health Management Practice. 2008; 14(5), 471-475.

10. Klein SJ, Tesoriero JM, Leung S-YJ, Heavner KK, Birkhead GS. Screening Persons Newly Diagnosed with HIV/AIDS for Risk of Intimate Partner Violence: Early Progress in Changing Practice. J Public Health Manag Practice. 2008; 14(5): 420-428.

11. Tesoriero J, Battles H, Heavner K2, Leung SY, Nemeth C, Pulver W., Birkhead GS, The Effect of Name-Based Reporting and Partner Notification on HIV Testing in New York State. American Journal of Public Health. 2008; 98: 728-735. PMID: 18356570 12. Birkhead GS, Klein SJ, Candelas AR, O’Connell DA, Rothman JR, Feldman IS, Tsui DS, Cotroneo RA, Flanigan CA. Integrating multiple programme and policy approaches to hepatitis C prevention and care for injection drug users: A comprehensive approach. International Journal of Drug Policy. 2007 13. Wade NA, Birkhead GS, Warren BL, Charbonneau TT, French T, Wang L, Baum J, Tesoriero J, Savicki R. Abbreviated Regimens of Zidovudine Prophylaxis and Perinatal Transmission of the Human Immunodeficiency Virus. New England Journal of Medicine. 1998; 339(20): 1409-14. PMID: 9811915 Immunizations: I have contributed to the evidence base for vaccine preventable disease programs in the US including data that helped influence the national 2-dose measles vaccination policy, showed that WIC clinics are effective locations to promote vaccinations, contributed to national vaccine policy on vaccine financing, and examined the barriers to effective immunization programs. I served on the CDC Advisory Committee for Immunization Practices (ACIP) from 2001 to 2005. I served on the National Vaccine Advisory Committee (NVAC) of the National Vaccine Program Office, US Department of Health and Human Services (DHHS) from 2006 to 2011, including serving as chair from 2008 to 2011.

1. Bednarczyk RA, Birkhead GS. Evaluating the most effective distribution strategies to assure administration of pandemic H1N1 influenza vaccine to New York State children and adolescents: Evaluation using the New York State Immunization Information System. Journal of Public Health Manag Pract. 2013 Nov-Dec; 19(6):589-97. PMID: 23299656.

2. Bednarczyk RA3, Birkhead GS, Morse DL, Doleyres H, McNutt LA. Human papillomavirus vaccine uptake and barriers: association with perceived risk, actual risk and race/ethnicity among female students at a New York State university, 2010. Vaccine. 2011 Apr 12;29(17):3138-43. PMID: 21376797.

3. Birkhead GS, Orenstein W, Almquist J. Reducing Financial Barriers to Vaccination in the United States: Call to Action (commentary). Pediatrics 2009; 124:S451-S454. PMID: 19948574.

4. Birkhead GS, LeBaron CW, Parsons P, Grabau JC, Barr-Gale L, Fuhrman J, Brooks S, Rosenthal J, Hadler SC, Morse DL. The Immunization of Children Enrolled in the Special Supplemental Food Program for Women, Infants, and Children (WIC): The Impact of Different Strategies. JAMA. 1995; 274(4): 312-316. PMID: 7609260 Public Health Surveillance: I have worked to define and improve public health surveillance systems in the US, including efforts to improve surveillance systems, to evaluate their characteristics, and to leverage electronic health records for surveillance purposes. I lead the planning and chaired the 1994 National Public Health Surveillance Conference, served as the state representative on the CDC committee that revised the national surveillance evaluation guidelines in 2000, served on the committee that reviewed surveillance for smallpox vaccine adverse events in 2003-4, published evaluations of several infectious disease surveillance systems in New York State, and worked to implement public health surveillance using health records. I was a major contributor to the development of the first national case definitions for public health surveillance as the

surveillance lead for Council of State and Territorial Epidemiologists. I co-author of 3 book chapters with nationally recognized experts on public health surveillance.

1. Birkhead GS, Klompas M, Shah NR. Uses of Electronic Health Records for Public Health Surveillance to Advance Public Health. Annual Rev Public Health. 2015 (March);36:345-359. PMID: 25581157 2. Birkhead GS, Maylahn CM. State and local public health surveillance. In: Principles and Practice of Public Health Surveillance, Third Edition. Lee LM, Teutsch SM, Thacker SB, St. Louis ME (eds.). New York: Oxford University Press. 2010, pp 381-398.

3. Recommendations from the Guidelines Working Group. Gorman RR, Lee LM, Horan JM, Milstein RC, Pertowsky CA, Waller MN, Birkhead GS. Updated Guidelines for Evaluating Public Health Surveillance Systems. CDC, Morbidity and Mortality Weekly Report 2001; 50(No. RR-13): 1-29.

4. Thacker SB, Birkhead GS. Surveillance. In: Field Epidemiology, Third Edition. Gregg, M (ed.). New York: Oxford University Press. 2008, pp 38-64.

Public Health Education: I have been a leader in applied public health education including leading the development of competencies for applied epidemiology. I co-chaired the national committee that developed educational competencies for applied epidemiology in 2007-8. I co-edited the 2008 supplement to Public Health Reports on the applied epidemiology competencies. I have also promoted the academic health department model of applied public health education. I helped establish the School of Public Health at the University at Albany, a unique model of applied public health education that is a partnership between the New York State Department of Health and the University.

1. Birkhead GS, Eidson M, Dewar D, Nasca P, Morse DL, Shah NR. Integrating Public Health Education in a Public Health Practice Setting: The Experience of the School of Public Health, University at Albany and the New York State Department of Health. Journal of Public Health Manag Pract 2014;20(3):278284. PMID: 24667187.

2. Birkhead GS, Davies J, Miner K, Lemmings J, Koo D. Developing Competencies for Applied Epidemiology: From Process to Product (commentary). Public Health Reports. 2008; 123(Supp): 67118. PMID: 18497021.

3. Koo D, Birkhead GS, Reingold AL. Competency-based epidemiologic training in public health practice.

Public Health Reports. 2008; 123 Suppl 1:1-3.] PMID: 18497008.

4. Birkhead GS, Koo D. Professional Competencies for Applied Epidemiologists: A Roadmap to a More Effective Epidemiologic Workforce (Editorial). Journal of Public Health and Management Practice.

2006; 12(6): 501-504. PMID: 17041296 D. Research Support Current Research Support: None.

Prior Research Support (Note: Dr. Birkhead’s affiliation with these grants ceased upon his retirement from the NYSDOH in August, 2015).

1U01TP000567 Birkhead (PI) 09/30/13 – 09/29/15 $331,443 CDC/OPHPR-NCEH CDC Public Health Emergency Preparedness and Response to Aid Recovery from Hurricane Sandy (Priority C) The goals of this research are to evaluate the public health system in its preparation, response, and recovery from Hurricane Sandy, and to research modifications needed to improve future response and recovery.

1U50CK000199 Birkhead (PI) 01/01/12 - 12/31/16 $3,115,873 CDC/CK,IP Emerging Infections Program (EIP) The major goals of this research program are to conduct population based enhanced surveillance for a number of emerging infections of national importance including foodborne disease, influenza, Clostridium difficile, Lyme

and other tick-borne diseases and to conduct special studies such as healthcare-associated infections, antimicrobial use and monitoring vaccine effectiveness for Human Papilloma Virus Vaccine.

OMB No. 0925-0001 and 0925-0002 (Rev. 10/15 Approved Through 10/31/2018)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Eli Samuel Rosenberg eRA COMMONS USER NAME (credential, e.g., agency login): ESROSE2 POSITION TITLE: Associate Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

Cornell University, Ithaca NY

DEGREE (if applicable) BS

Completion Date MM/YYYY 05/2006

Emory University, Atlanta GA

PhD

12/2012

INSTITUTION AND LOCATION

FIELD OF STUDY Biometry & Statistics, Biology Epidemiology

A. Personal Statement I am an epidemiologist who has been conducting public health research for the previous 12 years, focusing on HIV prevention for the previous 10 years. As a faculty member at the University at Albany and formerly with the PRISM Health group at Emory University, I manage a diverse portfolio of HIV and other infectious disease studies and programs. These projects are supported by grants from NIH and CDC. My research focuses on epidemiologic methods and analyses for understanding pertinent issues in HIV, STI, HCV, and arbovirus surveillance, prevention, and social determinants. I have specifically focused on sexual and racial minorities and the infectious disease disparities they face, with considerable effort spent on cohort studies. I have been previously a guest scientist at the CDC Division of HIV/AIDS Prevention’s Behavioral and Clinical Surveillance Branch and am currently with the Division of Vector Borne Diseases, Dengue Branch. I am the Co-PI of CAMP, overseeing the development of applied models to inform public health in HIV, STI, viral hepatitis, and tuberculosis.

B. Positions and honors Positions 2006 – 2010 Data Analyst / Biostatistician. Biostatistics Consulting Center, Department of Biostatistics.

Emory University Rollins School of Public Health 2009 – 2010 Data Analyst. Department of Epidemiology. Emory University Rollins School of Public Health 2010 – 2012 Associate Director, Research Projects. Department of Epidemiology. Emory University Rollins School of Public Health 2012 – 2016 Senior Epidemiologist (guest researcher). Behavioral and Clinical Surveillance Branch, CDC Division of HIV/AIDS Prevention 2013 – 2017 Assistant Professor. Department of Epidemiology. Emory University Rollins School of Public Health 2016 – 2017 Associate Director. Prevention Science Core, Emory Center for AIDS Research. Emory University 2017 – present Adjunct Associate Professor. Department of Epidemiology. Emory University Rollins School of Public Health 2017 – present Associate Professor. Department of Epidemiology and Biostatistics. University at Albany School of Public Health, State University of New York 2016 – present Senior Epidemiologist (guest researcher). Dengue Branch, CDC Division of Vector-borne Diseases Honors 2018

CDC National Center for Emerging and Zoonotic Infectious Diseases, Nakano citation Rosenberg biosketch, page 1

2018 2015 2016

CDC National Center for Emerging and Zoonotic Infectious Diseases, award for collaboration during Zika virus outbreak CDC National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Director’s Award CDC Charles C. Shepard Award: Data Methods and Study Design category

Editorial 2014 – present Associate Editor, PLoS One 2017 – present Senior Editor, Annals of Epidemiology C. Contributions to Science 1. Studies to quantify and explain the causes of racial disparities in HIV infection among men who have sex with men (MSM) This area has been one of the main priorities of my research program. Black MSM are a consistently disproportionately affected group in the US HIV epidemic, by most measures of HIV occurrence and infection outcomes. Atlanta is a crucial focal point with the 2nd highest number of new diagnoses among black men who have sex with men in 2011. Across NIH-funded 4 R01 and 1 R21 studies, in which I have served as either PI or co-PI leading the analytic team, we have been extensively studying this health disparity. Across numerous papers on these studies to date, we have documented the extent of the HIV incidence disparities by race in Atlanta, and its causes related to socioeconomic position, sexual network properties, and STI co-infection. In addition to presenting these findings at national and international meetings, these have been featured in a number of media stories and advocacy initiatives.

These studies have been cited by the White House Office of National AIDS policy and have generally contributed to their renewed spotlight on the epidemic among minority MSM in the US Southeast.

1. Sullivan P, Rosenberg ES, Sanchez T, Kelley CF, Luisi N, Cooper HL, DiClemente R, Wingood G, Frew PM, Salazar LF, del Rio C, Mulligan MJ, Peterson JL. Explaining Racial Disparities in HIV Incidence in a Prospective Cohort of Black and White Men Who Have Sex With Men in Atlanta, GA: A Prospective Observational Cohort Study. Annals of Epidemiology. 2015 June. 25(6): 445–454 PMCID: PMC4433604 2. Hernández-Romieu AC, Sullivan PS, Rothenberg RB, Grey JA, Rosenberg ES. Heterogeneity of HIV prevalence among the sexual networks of Black and White MSM in Atlanta: illuminating a mechanism for increased HIV risk for young Black MSM. Sexually Transmitted Diseases. 2015 Sep;42(9):505-512. PMCID: PMC4536576 3. Goodreau SM, Rosenberg ES, Jenness SM, Luisi N, Stansfield SE, Millet GA, Sullivan PS. Sources of racial disparities in HIV prevalence in men who have sex with men in Atlanta, GA, USA: a modelling study. Lancet HIV. 2017 Jul;4(7):e311-e320. PMID: 28431923 4. Rosenberg ES, Purcell DW, Grey JA, Hankin-Wei A, Hall E, Sullivan PS. Rates of Prevalent and New HIV Diagnoses by Race and Ethnicity among Men Who Have Sex With Men, US States, 20132014. Annals of Epidemiology. 2018 Nov;108(S4):S266-S273. PMID: 30383430 2. Modeling of the US HIV care continuum to explain key phenomena The continuum of care for HIV infection, a series of key steps from diagnosis through viral suppression, has emerged as an important tool for understanding the state of HIV care in populations. Further, numerous clinical studies over the past decade have provided evidence that antiretroviral treatment is a powerful tool for HIV prevention. In two recent modeling studies, I and my colleagues used the HIV care continuum as a framework for understanding HIV transmission and incidence in the United States.

These studies elucidated national patterns in HIV transmission overall and MSM race disparities. A third study adopted the HIV care continuum framework for HIV prevention via pre-exposure prophylaxis (PrEP), to describe the prevalence of PrEP barriers and how they differentially affect MSM by race.

These studies have influenced the national conversation around HIV care through substantial media coverage, scientific citations, and inclusion in White House Office of National AIDS Policy reports.

Rosenberg biosketch, page 2

1. Rosenberg ES, Millett GA, Sullivan PS, del Rio C, Curran JW. Understanding the HIV disparities between black and white men who have sex with men in the USA using the HIV care continuum: a modelling study. The Lancet HIV. 2014 Dec;1(3):e112-e118. PMCID: PMC4269168 2. Skarbinski J, Rosenberg ES, Paz-Bailey Gabriela, Hall HI, Rose C, Viall A, Fagan J, Lansky A, Mermin J. Human Immunodeficiency Virus (HIV) Transmission at Each Step of the HIV Care Continuum. JAMA Internal Medicine. 2015 Apr;175(4):588-96 PMID: 25706928 3. Kelley CF, Kahle E, Siegler AJ, Sanchez TH, del Rio C, Sullivan PS, Rosenberg ES. Applying a PrEP Continuum of Care for Men who Have Sex with Men in Atlanta, GA. Clinical Infectious Diseases. 2015 Nov 15;61(10):1590-7. doi: 10.1093/cid/civ664. PMCID: PMC4614414 4. Rosenberg ES, Bradley H, Buchascz K, McKenney J, Paz-Bailey G, Prejean J, Brooks JT, Shouse L, Sullivan PS.. Improving Estimation of HIV Viral Suppression in the United States: a Method to Adjust HIV Surveillance Estimates from the Medical Monitoring Project Using Cohort Data.

American Journal of Epidemiology. 2018 Sep 1;187(9):1962-1969. PMID: 29635352 3. Measuring the prevalence and relevance of sexual concurrency among men who have sex with men (MSM) in the United States Sexual concurrency is the phenomenon of being engaged in multiple contemporaneous partnerships and is a sexual network property that catalyzes HIV transmission. Although it had been welldocumented in sub-Saharan African heterosexual epidemics, it remained little studied in MSM, who comprise the majority of new HIV infections in the United States and have meaningfully different partnering patterns. Through a series of analytical studies applied to an online HIV cohort study of MSM that my colleagues and I conducted, we applied a newly developed concurrency assessment tool and demonstrated that the prevalence of both concurrent anal intercourse and concurrent unprotected anal intercourse was high and likely placing black MSM at increased risk for HIV infection. The methodology developed for measuring concurrency has since been utilized in a number of HIV research studies.

1. Rosenberg ES, Khosropour CK, Sullivan PS. High prevalence of sexual concurrency and concurrent unprotected anal intercourse across racial/ethnic groups among a national, webbased study of men who have sex with men in the United States. Sexually Transmitted Diseases. October 2012; 39(10):741-6. PMCID: PMC3457013 2. Rosenberg ES, Rothenberg RB, Kleinbaum DG, Stephenson RB, Sullivan PS. The implications of respondent concurrency on sex partner risk in a national, web-based study of men who have with men in the United States. J Acquir Immune Defic Syndr. August 2013; 63(4) 514-21 PMCID: PMC3700588 3. Rosenberg ES, Rothenberg RB, Kleinbaum DG, Stephenson RB, Sullivan PS. Assessment of a new web-based sexual concurrency measurement tool for men who have sex with men.

J Med Internet Res. 2014 Nov 10;16(11):e246. PMCID: PMC4260005 4. Training future generations of skilled epidemiologists During my time as an epidemiology faculty member, I have extensively taught epidemiologic, biostatistical research methods across 4 full-semester lecture courses and a variety of short courses and guest lectures. I also routinely guest lecture on topics in HIV prevention and surveillance. These courses were at both my home institutions of UAlbany and Emory schools of public health, CDC, and online continuing education platforms. I have additionally mentored 8 MPH students, 9 doctoral students, 6 post-doctoral fellows, and 2 junior faculty members on thesis projects and training grants.

Rosenberg biosketch, page 3

1. Kleinbaum, Kupper, Nizam, Rosenberg. Applied Regression Analysis and Other Multivariable Methods, 5th Edition. Cengage. 2013 Complete List of Published Work: https://www.ncbi.nlm.nih.gov/pubmed/?term=eli%20rosenberg D. Research support Active 1U38PS004646-01 (PI: Rosenberg, Sullivan) 09/30/14 – 09/29/19 CDC/NCHHSTP Enhancing models of HIV, viral hepatitis, STIs, and tuberculosis to inform and improve public health impact This is a large consortium working with the CDC National Center for HIV, Viral Hepatitis, STD, and TB Prevention under a cooperative agreement to construct economic and epidemic models for directing national, state, and local prevention activities.

Role: co-PI NYS DOH (PI: Rosenberg) 06/01/18 – 5/31/20 Research to inform Hepatitis C elimination strategies in New York State $627,942 This is a multi-phased research agenda to quantify the burden of Hepatitis C in New York State, to study highrisk populations upstate, and to evaluate innovative care models for HCV care.

Role: PI 1R01DA038196-01 (PI: Rosenberg, Sullivan) 06/15/14 – 05/31/19 NIH/NIDA Understanding substance use and incident HIV/STI among young black MSM This project is a cohort study of HIV-negative young black MSM ages 18-29 that aims to further understanding of the relationships between substances and HIV/STI incidence and risk behaviors, and suggest possible interventions.

Role: MPI 16IPA1609627 (PI: Rosenberg) 2/01/2019 – 1/31/2020 CDC/NCEZID/DVBD $30,698 Intergovernmental Personnel Act (IPA) Agreement Epidemiologic support and consultation to the CDC Dengue Branch in San Juan, Puerto Rico, focusing on the conduct of Zika and Dengue virus-related research.

Role: PI Previous 3 years 1R01AI112723-01A1 (PI: Sullivan) 03/13/2015 – 02/28/19 NIH/NIAID Understanding Disparities in Effective HIV Treatment And Prevention: Involvement+ This is a cohort study of black and white non-Hispanic MSM living with HIV that is seeking to understand racial differences in longitudinal HIV care continuum outcomes.

Role: Co-I 5U19HD089881-02 (PI: Hightow-Weidman, Sullivan) 9/30/2016 – 5/31/21 NIH/NICHD HIV Adolescent Trials Network (ATN): The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuum The iTech is a coordinating center responsible for the conduct of a portfolio of HIV prevention and treatment randomized controlled trials, focused on electronic and mobile interventions for adolescent men who have sex with men, across 6 academic institutions, and 10 urban clinical sites.

Rosenberg biosketch, page 4

Role: PI, Analytic Core (data coordinating center) R21HD075662 (PI: Goodreau) 08/15/13 – 07/31/16 NIH/NICHD Improving sexual network transmission models to explain HIV disparities between Black and White MSM This project seeks to integrate detailed risk behavioral and network data collected on MSM in Atlanta into a comprehensive agent-based HIV transmission model, with the purpose of understanding the drivers of the racial disparities in HIV infection in Atlanta.

Role: Co-I (Emory site PI) 2R44HD078154-02A1 (PI: Cecil, Sullivan) 09/25/14 – 07/31/16 NIH/NICHD A study to improve the fit of HIV prevention methods This is a Small Business Innovation Research Phase II project to conduct a randomized clinical trial of fitted condoms, in order to understand their impact on condom fit and pleasure.

Role: Co-I P30 (PI: Brown, Mustanski) NIH/NIDA Center for Prevention Implementation Methodology for Drug Abuse and HIV (Ce-PIM) This is a center, housed at Northwestern University, dedicated to developing, coordinating, and applying modeling methods for HIV and drug abuse research, and focused on furthering the goals of the National HIV/AIDS Strategy.

Role: Co-I (Emory Site PI) 1R21HD080523-01A1 (PI: Cassels) 07/05/2015 – 06/30/17 NIH/NICHD Mathematical Models to Inform Effective Home-use HIV Testing Strategies for MSM This is an agent-based modeling study of the potential impact of at-home HIV testing on HIV transmission among MSM in both Atlanta and Seattle.

Role: Co-I (Emory site PI) U01MD011274 (PI: Bauermeister, Stephenson, Sullivan) 07/28/16 – 02/28/21 NIH/NICHD Reducing HIV vulnerability through a multilevel life skills intervention for adolescent men.

This is a multi-region, randomized controlled trial of iCON, an online intervention for young men who have sex with men.

Role: Co-I 1U01PS004977-01 (PI: Sullivan) 09/01/15 – 08/31/19 CDC/NCHHSTP Mobile Messaging Intervention to Present New HIV Prevention Options for MSM This is a cooperative agreement with the CDC Division of HIV/AIDS Prevention to conduct a two-phase study that seeks to develop an intervention to deliver prevention messages to men who have sex with men and then conduct a randomized control trial of its efficacy in three US cities.

Role: Co-I 5P30AI 050409-12 (PI: del Rio) 09/30/02 – 07/31/16 Center for AIDS Research Core C: Prevention The mission of the Emory Center for AIDS Research (CFAR) Core C: Prevention is to facilitate the use of measurement technologies in the conduct of qualitative and behavior research, enable the implementation and adaptation of evidence-based HIV/AIDS interventions, provide training and consultation on the design and conduct of HIV/AIDS-related social and behavioral science research, and to support the activities of the CFAR Social and Behavioral Science Research Network (SBSRN).

Role: Associate director, Prevention Sciences Core (Core C) Rosenberg biosketch, page 5

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Udo, Tomoko eRA COMMONS USER NAME (credential, e.g., agency login): UDOTOMO POSITION TITLE: Assistant Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

Boston University, Boston, MA

B.A.

05/03

Psychology

Rutgers University, Piscataway, NJ

M.S.

10/05

Rutgers University, Piscataway, NJ

Ph.D.

10/09

Behavioral Neuroscience Public Health

Postdoc

07/11

Substance Abuse

INSTITUTION AND LOCATION

Center of Alcohol Studies, Rutgers University, Piscataway, NJ

FIELD OF STUDY

A. Personal Statement The overarching goal of my research program is to identify ways to improve health care for individuals with various addictive behaviors, including drug abuse and behaviors partly overlap with drug addiction such as binge eating/obesity, as well as other mental health problems. I use a wide range of research approaches, from basic laboratory behavioral experiments, quasi-experimental studies, to secondary data analysis of epidemiological data. Similar to many communities across the U.S., NYS has suffered from increased mortality and morbidity from opioid overdose. I am currently involved in two funded collaborative research studies with NYS Department of Health: one study aims to understand the impact of extended harm reduction service model (Drug User Health HUB) on opioid overdose prevention, and another study aims to improve uptake of treatment for hepatitis C (HCV) among persons who inject drugs (PWID). Since fall 2016, I have been closely working with the “Chatham Cares 4 U (CC4U)”. My role has been to keep track of the rate of program uptake and linkage to treatment, as well as efficiency of that process. Because these are relatively new projects, I do not have a record of publications in this area yet, but should represent my expanding expertise that are crucial to complete the proposed project. I have also extensively conducted secondary data analysis of publicly available epidemiology data with theme around psychosocial stress and health disparities, including a history of incarceration, discrimination, and childhood adversity, which has been part of the reason for my strong commitment to conduct research to potentially promote the police diversion programs. Finally, I also teach regularly “Addiction in Public Heath” for master- and doctor-level students, which should also demonstrate depths of my knowledge regarding various issues related with addiction. I have extensive experiences with leading multidisciplinary research studies involving substance users as a PI, and most of these studies require following up participants. These experiences should strongly support my ability to lead and complete this project as a PI. 1. Vasquez, E., Udo, T., Corsino, L., & Shaw, B. A. (in press). Racial and ethnic disparities in the association between adverse childhood experience, perceived discrimination and body mass index in a national sample of U.S. older adults. Journal of Nutrition in Gerontology and Geriatrics.

2. Udo, T. (2019). Chronic medical conditions in U.S. adults with incarceration history. Health Psychology, 38(3), 217-225. PMID: 30762401 3. Udo, T. & Grilo, C. M. (2017). Cardiovascular disease and perceived weight, racial, and gender discrimination in U.S. adults. Journal of Psychosomatic Research, 100, 83-88. PMCID: PMC5598460

4. Udo, T., Vasquez, E., & Shaw, B. A. (2015). A lifetime history of alcohol use disorder increases risk for chronic medical conditions after stable remission. Drug and Alcohol Dependence, 157, 68-74.

PMID:26482092 B. Positions and Honors Positions and Employment 2004-2009 Graduate Assistant, Cognitive Neuroscience Laboratory, Center of Alcohol Studies, Rutgers University 2009-2011 Postdoctoral Associate, Center of Alcohol Studies, Rutgers University 2011-2014 Associate Research Scientist, Psychiatry, Yale University School of Medicine 2014Assistant Professor, Department of Health Policy, Management, and Behavior, School of Public Health, University at Albany, State University of New York Honors 2007, 2010, 2011 2007 2008 2008 2010 2010 2012 2011-2014 2017 2018

ECPN Travel Award, Society for Prevention Research (SPR) National Institute on Drug Abuse (NIDA) Women & Gender Junior Investigator Travel Award, the College on Problems of Drug Dependence (CPDD) Student Merit Meeting Award, Research Society for Alcoholism (RSA) Travel Award for DIV 50/28 & NIAAA/NIDA Poster Session/Social Hour, American Psychological Association (APA) Leon A. Greenberg Award for outstanding graduate student by the Center of Alcohol Studies, Rutgers University Invited Fellow, Family Research Consortium 5 Summer Institute National Institute on Drug Abuse (NIDA) Women & Gender Junior Investigator Travel Award, CPDD Yale Building Interdisciplinary Research Careers in Women's Health (BIRCWH) scholar Society for Behavioral Medicine Scientific Meeting Citation Award (2017) President's Awards for Exemplary Public Engagement by the University at Albany

Other Experience and Professional Memberships 2002Phi Chi 2008Member – American Psychological Association (APA; Divisions 5 & 50) 2009Member – Research Society on Alcoholism 2009Member – Society for Prevention Research 2014Consulting Editor, Psychology of Addictive Behaviors (APA Division 50 journal) 2014Early Career Reviewer (ECR) program at the Center for Scientific Review (CSR), National Institutes of Health 2016Member, University at Albany President’s Advisory Council on the Prevention of Alcohol and Other Drug Abuse and Related Risk Behaviors 2016Review Board - American Journal of Health Behaviors 2018 Women in Higher Education Steering Committee, University at Albany C. Contribution to Science 1. Binge-eating disorder (BED) is the most prevalent form of eating disorder (ED), but was not part of a formal ED diagnosis until the DSM-5. It is also considered a psychiatric disorder that overlaps with “addiction” (e.g., loss of control, overconsumption of palatable foods, compulsivity). There have been substantial changes in diagnostic criteria for EDs between DSM-IV and DSM-5, and thus there have been significant interests in both scientific and medical communities to understand the impact of these changes. Primarily using a data set from the National Epidemiologic Survey of Alcohol and Related Conditions Third (NESARC-III), I have conducted a series of research that updated epidemiological data on BED and other EDs among the U.S. adults since 2007. My studies also sparked debates over assessment of psychiatric disorders in general. a. Coffino, J. A., Udo, T., & Grilo, C. M. (accepted). Rates of help-seeking in U.S. adults with lifetime DSM-5 eating disorders: Prevalence across diagnoses and sex and ethnic/racial differences. Mayo Clinic Proceedings.

b. Udo, T., & Grilo, C. M. (in press). Reply to: Insight may limit identification of eating disorder. Biological Psychiatry. PMID: 30579531 c. Udo, T. & Grilo, C. M. (2019). Psychiatric and medical comorbidity of DMS-5 eating disorders in the U.S. adults. International Journal of Eating Disorders, 52(1), 42-50. PMID: 30756422 d. Udo, T. & Grilo, C. M. (2018). Prevalence and correlates of DSM-5defined eating disorders in a nationally representative sample of U.S. adults. Biological Psychiatry, 84(5), 345-354. PMID: 29859631 2. Using human laboratory behavioral models, I have investigated whether heart rate variability (changes in beat-to-beat interval) may be a good intervention target for prevention and treatment of problematic alcohol use and overeating. a. Vaschillo, G. E., Bates, M. E., Vaschillo, B., Lehrer, P., Udo, T., Mun, E.Y., & Ray, S. Heart rate variability response to alcohol, placebo, and emotional picture cue challenges: effects of 0.1 Hz stimulation. 2008. Psychophysiology, 45(5), 847-858. PMCID: PMC2964051 b. Udo, T., Bates, M. E., Vaschillo, E. G., Vaschillo, B., Lehrer, P., Mun, E. Y., & Ray, S. Gender differences in the effects of alcohol on social drinkers’ physiological response to emotional, alcoholrelated, and drug-related stimuli. 2009. Psychology of Addictive Behaviors, 23(2), 196-204. PMCID: PMC2964059 c. Udo, T., Grilo, C. M., Brownell, K. D., Weinberger, A. H., DiLeone, R. J., & McKee, S. A. (2013).

Modeling the effects of negative and positive mood on the ability to resist eating high-caloric food in obese and non-obese individuals. Eating Behaviors, 14(1), 40-46. PMCID: PMC3633072 d. Udo, T., Weinberger, A. H., Grilo, C. M., Brownell, K. D., DiLeone, R. J., Lampert, R., Matlin, S. L., & McKee, S. A. (2014). Heightened vagal activity during high-calorie food presentation in obese compared with non-obese individuals: Results of a pilot study. Obesity Research and Clinical Practice, 8(3), e201-98. PMCID: PMC4031442 3. I also use large epidemiological data sets to understand the role of psychosocial stressor such as childhood adversity and discrimination as a risk factor for addictive behaviors (drug addiction and addiction-like behaviors such as binge eating) and barriers for access to health care and seeking treatment among these individuals. In study a, I demonstrated female-specific association between stressful life events and weight gain. I also extensively studied the relationship between perceived discrimination and health (b and c). a. Udo, T., Grilo, C. M., & McKee, S. A. (2014). Gender differences in the impact of stressful life events on changes in body mass index. Preventive Medicine, 69, 49-53. b. Udo, T. & Grilo, C. M. (2016). Perceived weight discrimination, childhood maltreatment, and weight gain in U.S. adults with overweight/obesity. Obesity, 24, 1366-1372. PMCID: PMC5215793 c. Udo, T., Purcell, K., & Grilo, C. M. (2017). Perceived weight discrimination and chronic medical conditions in adults with overweight and obesity. International Journal of Clinical Practice. PMCID: PMC5215793 4. I examined whether disparities in psychosocial and metabolic functioning in subgroups of individuals who sought treatment for comorbid binge eating disorder (BED) and obesity. Two studies (a & b) found heightened vulnerability to metabolic abnormalities in men with comorbid obesity and BED, compared with their female counterparts. In another study (c), we demonstrated poorer metabolic and psychosocial functioning in current smokers with comorbid BED and obesity. In the last study (d), we demonstrated similarities in the impact of comorbid BED and obesity between Caucasian and African American women. Studies a and d in particular have highlighted the importance of screening of BED in overweight/obese individuals as men and racial minorities are underserved populations in terms of seeking treatment for BED. a. Udo, T., McKee, S. A., White, M. A., Masheb, R. M., Barnes, R. D., & Grilo, C. M. (2013). Sex differences in biopsychosocial correlates of binge eating disorder: A study of treatment-seeking obese adults in primary care setting. General Hospital Psychiatry, 35(6), 587-591. PMCID: PMC3845204 b. Udo, T., McKee, S. A., White, M. A., Masheb, R. M., Barnes, R. D., & Grilo, C. M. (2014). Menopause and metabolic function in obese individuals with binge eating disorder. Eating Behaviors, 15, 182-185.

PMCID: PMC4032475

c. Udo, T., White, M. A., Barnes, R. D., Ivezaj, V., Morgan, P., Meshab, R. M., & Grilo, C. M. (2015).

Psychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesity. Addictive Behaviors, 53, 46-52. PMCID in process. d. Udo, T., White, M. A., Barnes, R. D., McKenzie, K. C., Genao, I., Garcia, R., & Grilo, C. M. (2016).

Correlates of binge eating disorder in Caucasian and African American women with obesity in primary care setting, European Eating Disorder Review, 24(3), 181-6. PMCID: PMC5076468 Complete List of Published Work in MyBibliography: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47360750/?sort=date&direction=ascending D. Research Support Ongoing Research Support Centers for Disease Control and Prevention Kitty Gelberg (PI) 09/30/18-09/29/21 “Evaluation of Community-based Drug User Health Hubs to Reduce Opioid Overdoses in NY State” This project aims to evaluate the effectiveness of Drug User Health HUB model, which offers health and social services (e.g., on-site buprenorphine prescribing, assistance with legal and social issues) in addition to services traditionally offered by syringe exchange programs (i.e., clean needles and other paraphernalia, naloxone, STD prevention), in preventing future opioid overdose.

Role: Co-I The New York State Department of Health AIDS Institute (MOU) Eli Rosenberg & Tomoko Udo (PIs) 04/01/18-03/31/23 “Studies to understand the burden and factors associated with Hepatitis C in New York State” This study aims to: 1) obtain prevalence estimate of HCV among PWID in Upstate NY; 2) identify modifiable risk factors associated with positive HCV diagnosis and uptake of HCV treatment; and 3) evaluate three new innovative HCV care models specifically for PWID. Role: Co-PI University at Albany, Faculty Research Awards Program Tomoko Udo (PI) 05/01/18-04/30/20 “Preliminary Evaluation of the Police-Assisted Addiction and Recovery Initiative: A Case Study with the Chatham Cares 4U” This project aims to evaluate the effectiveness and implementation process of a police-led treatment referral program that has been implemented in Chatham, NY since July 2016. The preliminary effectiveness of the program on individual life trajectories is evaluated by comparing multiple life outcomes between CC4U participants and individuals who entered into substance use treatment through other referral sources.

Role: PI ABMRF/The Foundation for Alcohol Research Tomoko Udo (PI) 07/01/14-06/30/18 “Is Ghrelin Associated with Alcohol Craving and Self-Administration in Alcohol Use Disorders?”

Using a laboratory model of drinking behaviors, this project aims to examine the role of ghrelin, an appetite stimulating hormone, in alcohol use behaviors in individuals with alcohol use disorders.

Role: PI Completed Research Support University at Albany, Presidential Initiative Grant Tomoko Udo (PI) 02/28/17-06/20/18 “Enhancing the Role of Emergency Department in Fight against Opioid Epidemic: Preliminary Evaluation of Take-Home Naloxone Program” This project aims to evaluate the feasibility and effectiveness of providing overdose prevention training to opioid overdose victims, current opioid users, and their friends and family at emergency department by following up individuals up to 3 months. This study is being completed in collaboration with Catholic Charities of Albany. This was a university-wide seed grant program. The project was selected as one of 12 funded projects out of 65 applications.

Role: PI Junior Faculty Seed Grant Tomoko Udo (PI) Center for Social and Demographic Analysis, University at Albany “Childhood Maltreatment, Allostatic Load, and Substance Use in Adolescents�

01/01/16-08/31/16

This study aims to conduct a secondary data analysis of a 20-year longitudinal epidemiological data in the U.K. to understand the relationship between childhood maltreatment, allostatic load, and substance use behaviors during adolescence. In addition to substance use, I also plan to examine the relationship between childhood maltreatment, allostatic load, and risk for obesity in young adults.

Role: PI

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Jack DeHovitz eRA COMMONS USER NAME (credential, e.g., agency login): jdehovitz POSITION TITLE: Distinguished Service Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION

DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

University of California, Davis, California

B.S

06/1974

Genetics

University of Texas, Houston, Texas

M.P.H.

12/1975

Public Health

University of Texas Medical Branch, Galveston, Texas Dartmouth College

M.D.

06/1980

Medicine

MHCDS

06/2017

Health Care Delivery Science

A. Personal Statement I am highly qualified to be a member of the Training Advisory Committee for the D43 application and I have extensive experience with University of Zimbabwe graduate students and post-doctoral fellows. In addition to being fulltime faculty at SUNY Downstate, I am an adjunct Professor of Epidemiology at the SUNY, University at Albany. I have conducted extensive global health research and research training in Eastern Europe and Central Asia and serve as project director of the New York State International Training and Research Program (NYS-ITRP), continuously funded by the Fogarty International Center of the NIH since 1994, with activities currently funded in Ukraine and Kazakhstan. The NYS-ITRP is a joint project of SUNY Downstate, the University at Albany and the NYSDOH. Through this project we have studied the epidemiology of HIV and other STI’s in the region. Our studies were among the first to identify the role of injection drug use in the HIV epidemic in Eastern Europe as well as delineate challenges in accessing care. Currently over 100 of our graduates have returned to the region and are playing key roles in HIV research in Ministries of Health, infectious disease centers, NGO’s and universities, demonstrating my interest in HIV research training.

Additionally, I serve as director of a large clinical, training and research unit focused on HIV, related infections and substance use in Central Brooklyn. I manage a large extramural portfolio and supervise the provision of comprehensive HIV care to over 2000 patients in two sites in the borough. Therefore, I am very enthusiastic about serving as a member of the Training Advisory Committee for the D43 application.

B. Positions and Honors Professional and Academic Appointments 1981-1982 Assistant Resident in Medicine, The New York Hospital-Cornell Medical Center, New York, NY 1983-1985 Strang Fellowship in Public Health, Cornell University Medical College, New York, NY; Fellow in International Medicine, (Infectious Diseases), The New York Hospital, New York, NY 1985-1991 Assistant Professor, Department of Preventive Medicine and Community Health; Assistant Professor, Department of Medicine, Division of Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY 1991-1999 Associate Professor, Department of Preventive Medicine and Community Health; Associate Professor, Department of Medicine, Division of Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY 1993-present Director, HIV Center for Women and Children, SUNY Downstate Medical Center, Brooklyn, NY 1999-2011 Professor, Department of Medicine, Division of Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY 1999-present Adjunct Professor, Department of Epidemiology, SUNY School of Public Health, Albany, NY

2011-

Distinguished Service Professor, Department of Medicine, Division of Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY

Other Experience and Professional Memberships 2010 2011 2012 2013 2013 2013 2015 2014-2018

Member, Scientific Review Group, NIH: AITRP Review Member, Scientific Review Group, NIH Fogarty Member, Scientific Review Group, NIH Fogarty Member, Scientific Review Group, Russian NIH Review: Extramural R21 exploratory/developmental grant Member, Scientific Review Group, NIAID Special Emphasis Review Chair, Scientific Review Group, NIH Special Emphasis Review Reviewer, NIH: Fulbright-Fogarty Award, Institute of International Education Charter Member, Scientific Review Group, NIH: AIDS Clinical Studies in Epidemiology Study Section (ACE)

Honors 1979 2003 2008 2011

Elected AOA, University of Texas, Galveston SUNY Chancellor's Research Recognition Award Honorary Member Scientific Council, Pavlov State Medical University, St. Petersburg, Russia Distinguished Service Professor, SUNY Downstate Medical Center, Brooklyn, NY

C. Contribution to Science (Publications selected from over 150 articles, chapters, and reviews.)

Defining the cascade of care in low and medium income countries: A major challenge in the HIV epidemic is identifying those who are HIV infected and insuring their enrollment and engagement in care.

Using Georgia as a case study, a series of studies have emerged which defined both the scope of the epidemic and the national response. These studies have demonstrated that with universal access to ART and appropriate support, PWID with HIV can be maintained on therapy. However, overall mortality rates remain high due to late diagnosis and TB remains a significant cause of death.

1. Neduzhko O, Postnov O, Perehinets I, DeHovitz J, Joseph M, Odegaard D, Kaplan R, Kiriazova T. Factors Associated with Delayed Enrollment in HIV Medical Care among HIV-Positive Individuals in Odessa Region, Ukraine. J Int. Assoc. Provid. AIDS Care. 2017 Mar/Apr; 16:168-173.

PMID:28034344 2. Chkhartishvili N, Sharvadze L, Chokoshvili O, Bolokadze N, Rukhadze N, Kempker RR, Gamkrelidze A, DeHovitz JA, Del Rio C, Tsertsvadze T. Mortality and causes of death among HIV- infected individuals in the country of Georgia: 1989-2012. AIDS Res Hum Retroviruses.

2014 Jun; 30:560-6. PMID: 24472093 3. Chkhartishvili, N, Sharavdze, L, Chokoshvili, O, DeHovitz, JA, del Rio, C, Tsertsvadze, T. The cascade of care in the Eastern European country of Georgia. HIV Medicine. 2015 Jan;16:626105. PMID: 24919923 4. Tsertsvadze T, Chkhartishvili N, Sharvadze L, Dvali N, Chokoshvili O, Gabunia P, Abutidze A, Nelson K, DeHovitz J, del Rio C. Outcomes of Universal Access to Antiretroviral Therapy (ART) in Georgia. AIDS Research and Treatment. 2011;10:1-7. PMID: 21490781 Substance Use and the HIV epidemic in Eastern Europe: The HIV epidemic in Eastern Europe has been propelled in large part by people who inject drugs. Our publications were among the first to recognize this and subsequent publications have further defined this population. Subsequently we have shown a high incidence of HIV infection in new injectors in Estonia. More recent publications have reinforced the role that HIV testing and counseling may play in reducing transmission to uninfected sexual partners.

1. Ompad DC, Wang J, Dumchev K, Barska J, Samko M, Zeziulin O, Saliuk T, Varetska O, DeHovitz J. Patterns of harm reduction service utilization and HIV incidence among people who inject drugs in Ukraine: A two-part latent profile analysis. Int J Drug Policy. 2017 Feb 1;43:7-15. PMID:28160736

2. Makarenko I, Ompad DC, Sazonova Y, Saliuk T, DeHovitz J, Gensburg L. Trends in Injection Risk Behaviors among People Who Inject Drugs and the Impact of Harm Reduction Programs in Ukraine, 2007-2013. J Urban Health. 2017 Feb;94(1):104-114. PMID:28097615 3. Mazhnaya, Alyona, Andreeva, Tatiana I., Samuels, Steve, DeHovitz, Jack, Salyuk, Tetyana, McNutt, Louise-Anne. The potential for bridging: HIV status awareness and risky sexual behaviour of injection drug users who have non-injecting permanent partners in Ukraine. JAIS. 2014 February; 17:18825:02-06. PMID: 24560341 4. Uuskula A, Kalikova A, Zilmer K, Tammai L, DeHovitz J. The role of injection drug use in the emergence of HIV in Estonia. Int J Infect Dis. 2002; 6:23-27.

Sexually transmitted infections in lower and middle income countries: Following the collapse of the Soviet Union, Eastern Europe experienced rapidly increasing rates of sexually transmitted infections. In early studies we identified high-risk sexual behavior among men as one of the factors propelling the epidemic. Subsequent studies also noted high rates of chlamydia in the region. An additional study documented that 20% STI treatment episodes in Estonia was inconsistent with national guidelines, serving as yet another driver of high STI rates. Prior to the implementation of the HPV vaccine, we also documented a high prevalence of total and high risk HPV types.

1. Uuskula A, Kals M, Kosenkranius L, McNutt L, DeHovitz J. Population-based type-specific prevalence of high risk Human papillomavirus infection in Estonia. BMC Infectious Diseases.

2010;10:63. PMID: 20222944 2. Ghazaryan, LR, Muse, AG, Sarkisian TF, Morse, DL, DeHovitz JA. A survey to estimate the prevalence of genital Chlamydia trachomatis among women in Armenia. JIDC. 2007;1:214-216.

3. Uuskula A, McNutt LA, and DeHovitz J. Treatment of Sexually Transmitted Diseases in Estonia: consistency with the evidence-based medical principles. J Sex Trans Dis. 2004;31:631-635.

PMID: 15389004 4. Wilson TE, Uuskula A, Feldman J, Holman S, DeHovitz JA. A case-control study of beliefs and behaviors associated with STD occurrence in Estonia. J Sex Trans Dis. 2001;28:624-629. PMID: 11677383 Adherence to antiretroviral therapy: We have helped define the corollaries of adherence to therapy in people living with HIV in Eastern Europe. We determined that rates of adherence were similar to those in Western countries with non-perfect adherence associated with potential adverse consequences of taking antiretroviral therapy.

1. Chkhartishvili, Nikoloz, Rukhadze, Nino, Svanidze, Mariam, Sharvadze, Lali, DeHovitz, Jack A, Tsertsvadze, Tengiz, McNutt, Louise-Anne and del Rio, Carlos . Evaluation of multiple measures of antiretroviral adherence in the Eastern European country of Georgia. JAIS. 2014 April; 17: 18885:01-10. PMID: 24721464 2. Uuskula A, Laisaar KT, Raag M, Smidt J, Semjonova S, Kogan J, Amico KR, Sharma A, Dehovitz J. Antiretroviral therapy (ART) adherence and correlates to nonadherence among people on ART in Estonia. AIDS Care. 2012;24:1470-9. PMID:22533736 3. Laisaar K, Uuskula A, Sharma A, DeHovitz JA, Amico KR. Developing an adherence support intervention for patients on antiretroviral therapy in the context of the recent IDU-driven HIV/AIDS epidemic in Estonia. AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV. 2013;25:863-73. PMID:23391132 Biomarkers of HIV disease: Biomarkers have emerged as sensitive measures of the progression of HIV disease. Using a cohort of women with HIV, as well as the SMART study we have documented the use of markers as a measure of inflammation associated with HIV disease. An additional study led by me demonstrated a reduction of CRP after HAART. 1. Baker JV, Brummel-Ziedins K, Neuhaus J, Duprez D, Cummins N, Dalmau D, DeHovitz J, Lehmann C, Sullivan A, Woolley I, Kuller L, Neaton JD, Tracy RP for the INSIGHT SMART Study Team. HIV Replication Alters the Composition of Extrinsic Pathway Coagulation Factors and Increases Thrombin Generation. JAHA. 2013 July. PMID:23896681

2. Mansoor, A, Althoff K, Gange S, Anastos K, DeHovitz J, Minkoff, H, Kaplan, R, Holman, S, and Lazar, J. Elevated NT-pro-BNP Levels Are Associated with Comorbidities among HIV-Infected Women. AIDS Res Hum Retroviruses. 2009;25:997-1004. PMID: 19803714 3. DeHovitz JA, Feldman JG, Holman S, Minkoff H. High Sensitivity C – Reactive Protein and Response to Highly Active Antiretroviral Therapy in Women With HIV-1 Infection. J Acquir Immune Defic Syndr. 2006;42:383-4. PMID: 16639356 4. Feldman JG, Goldwasser P, Holman S, DeHovitz J, Minkoff H. C-reactive protein is an independent predictor of mortality in women with HIV-1 infection. J Acquir Immune Defic Syndr. 2003;32:210214. PMID: 12571532 Complete list of my public work in pubmed: http://www.ncbi.nlm.nih.gov/sites/myncbi/jack.dehovitz.1/bibliography/40443163/public/?sort=date& direction=ascending D. Research Support Ongoing Research Support Ongoing Research Support 5 H76 HA 00041 DeHovitz (PI) 10/01/91-12/31/20 U.S. Public Health Service/HRSA (Ryan White Part C Funding) Early Intervention with Respect to HIV Disease-STAR Health Center The goal of this program is to provide HIV primary care and counseling services to individuals with HIV disease. The clinic provides specialized gynecological care to HIV+ women.

Role: Project Director DeHovitz (PI) 07/01/06-06/30/20 HRSA (Subcontract through Columbia University) AIDS Education and Training Center The goal of this project is to provide on-site HIV training for health care providers in Brooklyn, especially targeting Brooklyn-based hospitals.

Role: Project Director DeHovitz (PI) 06/01/17-05/31/22 Fogarty International Center Ukraine HIV Research Training Program The overall focus of this program is to build capacity in conducting implementation science research that will address gaps in HIV care in Ukraine.

Role: Director D43TW010046-01A1DeHovitz (PI) 04/01/16-03/31/21 Fogarty International Center KNMU-SUNY HIV Research Training Program The overall focus of this program is to provide necessary research training and in-country research capacity building to enhance care and reduce new HIV infections in Kazakhstan.

Role: Director 1U01HL146202 Gustafson/Wilson (PIs) 04/01/19-03/31/26 National Institute of Allergy and Infectious Diseases MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) MWCCS is a collaborative research effort that aims to understand and reduce the impact of chronic health conditions—including heart, lung, blood, and sleep (HLBS) disorders—that affect people living with HIV. Downstate has participated in WIHS since 1992.

Role: Co-Investigator

Completed Research Support D71TW10044 Djibuti (PI) 06/01/16 – 05/31/19 Fogarty International Center Building Capacity, Ending AIDS in Georgia This project will support the development of doctoral level HIV research training opportunities at TSMU-ISPH, Georgia.

Role: Co-Investigator 1 H4AHA26221-01-00 DeHovitz (PI) 07/01/13-06/30/18 U.S. Public Health Service/HRSA HIV Specialist PA Training Program (National AIDS Education and Training Centers) This program establishes an HIV specialty track for physician assistant students at SUNY Downstate Medical Center (DMC).

Role: Project Director D43 TW00233 DeHovitz (PI) 06/01/93-04/30/18 Fogarty International Center New York State International Training Program (AITRP) The overall goal of this program is to provide HIV epidemiological and clinical training to physicians and scientists from the Baltics, Estonia, Armenia, Russia, Ukraine and Kazakhstan.

Role: Director 5U79SP016444 DeHovitz (PI) 09/01/13 – 08/31/16 U. S. Public Health Services/SAMHSA STAR Health Center Targeted Substance Abuse Treatment for Minority Women This project will expand SHC substance abuse and HIV treatment programs to Black and Hispanic women.

Interventions will include motivational interviewing, seeking safety, acupuncture, and case management and recovery services.

Role: Project Director 5U79SP016444 DeHovitz (PI) 09/30/10 – 09/29/15 U. S. Public Health Services/SAMHSA STAR Ready to Respond Initiative This project targets older adults (age 50+), impacted by substance abuse and HIV/AIDS. Objectives include providing targeted outreach, substance abuse/HIV prevention education, screening, HIV testing, and referrals.

Role: Project Director H4AHA22761 DeHovitz (PI) 09/01/11–08/31/15 U.S. Public Health Service/HRSA HIV Residency (National AIDS Education and Training Centers) The goal of this program is to expand opportunities to train medical residents in HIV/AIDS care and treatment at SUNY Downstate Medical Center (DMC).

Role: Project Director 1D43TW007384-1 Morse (PI) 06/01/93-05/31/15 Fogarty International Center, NIH New York State International Training Program This project seeks to provide epidemiologic and laboratory training related to Hepatitis to research scientists, clinicians and public health officials from the Republic of Georgia.

Role: Co-Director

OMB No. 0925-0001 and 0925-0002 (Rev. 10/15 Approved Through 10/31/2018)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Erika G. Martin eRA COMMONS USER NAME (credential, e.g., agency login): emartin300 POSITION TITLE: Associate Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

BA

05/01

Human Biology; French Literature

University of Michigan, Ann Arbor, MI

MPH

08/03

Epidemiology

Yale University, New Haven, CT

PhD

08/09

Health Policy and Administration

INSTITUTION AND LOCATION Brown University, Providence, RI

A. Personal Statement My scholarship aims to advance government capacity to translate evidence-based public health research into practice. My expertise includes mixed-methods research; HIV, STI, viral hepatitis, and related conditions; public health informatics; policy evaluation; public health services and systems; and academic/practice partnerships. I was a member of an Institute of Medicine committee that recommended data to monitor the effects of the Affordable Care Act and the National HIV/AIDS Strategy on HIV care; and was a member consultant of the National Committee on Vital and Health Statistics Work Group on HHS Data Access and Use. Other relevant research includes evaluating: federal funding allocation formulas for the Ryan White HIV/AIDS Program, interstate variation in substance abuse and mental health medications on state AIDS Drug Assistance Program formularies, the budget impact of expanded HIV screening, the temporarily repealed ban on federal funding for syringe exchange, how the Affordable Care Act will affect publicly financed HIV care, and New York’s HIV testing law. I have published in high-impact journals in public health, medicine, and public affairs. I have been a principal investigator or co-principal investigator on multiple collaborative projects with the New York State Department of Health to evaluate: how the state’s new HIV testing law will change epidemic outcomes and resource needs, the effects of the Ending the Epidemic policy initiative, efficient strategies to allocate Department of Health field staff to different HIV/STD prevention activities, the evolution of New York’s policy response to opioid overdose prevention, the effects of New York’s F-SHRP and DSRIP Medicaid waivers, and how to improve the sustainability and impact of state open health data platforms.

Four peer-reviewed publications supporting my qualifications: 1. Martin EG, Schackman BR. Treating and preventing HIV with generic drugs—barriers in the United States. New Engl J Med 2018; 378: 316-319. PMID: 29365306 2. Johnson BL, Tesoriero J, Feng W, Qian F, Martin EG. Cost analysis and performance

assessment of partner services for human immunodeficiency virus and sexually transmitted diseases, New York State, 2014. Health Serv Res; 2017; 52(Suppl 2): 2331-2342. PMID 28799163 3. Martin EG, MacDonald RH, Smith LC, Gordon DE, Tesoriero JM, Laufer FN, Leung S-YJ, Rowe KA, O’Connell DA. Mandating the offer of HIV testing: simulating the epidemiological impact and resource needs. J Acquir Immune Defic Syndr 2015; 68 (Suppl 1): S59-67. PMID 25545496 4. Martin EG, Meehan T, Schackman BR. AIDS Drug Assistance Programs: managers confront uncertainty and need to adapt as the Affordable Care Act kicks in. Health Aff 2013; 32(6): 1063-1071.

PMID 23733980

B. Positions and Honors Positions and Employment 2003-2004 Research Assistant for Tobacco Policy Projects, University of Lausanne, Switzerland 2004-2009 PhD Candidate, Yale University, New Haven CT (funding from Yale Graduate School, National Institute on Drug Abuse, and Agency for Healthcare Research and Quality) 2007-2009 Statistical Consultant to Robert Wood Johnson Foundation Clinical Scholars Program, Yale University, New Haven CT 2009-2015 Assistant Professor, Rockefeller College of Public Affairs and Policy, University at Albany-State University of New York, Albany NY 2010-2017 Fellow, Nelson A. Rockefeller Institute of Government, State University of New York, Albany NY 2013-2017 Director of Health Policy Studies, Nelson A. Rockefeller Institute of Government, State University of New York, Albany NY 2015-present Associate Professor, Rockefeller College of Public Affairs and Policy, University at Albany-State University of New York, Albany NY 2018-present PhD Program Director, Rockefeller College of Public Affairs and Policy, University at AlbanyState University of New York, Albany NY Other Experience 2010-2011 Statistical Consultant, New York City Law Department 2011-2012 Committee Member, Institute of Medicine, Review of Data Systems for Monitoring HIV/AIDS Care 2012, 2013 Abstract Reviewer, International AIDS Conference 2012, 2015 Grant Reviewer, California HIV/AIDS Research Program, University of California 2012 Judge, White House Startup America Policy Challenge 2013 Consultant on Systematic Literature Review Project, Virginia Commonwealth University 2014 Grant Reviewer, Robert Wood Johnson Foundation 2014 Abstract Reviewer, AcademyHealth Public Health Systems Research Interest Group Meeting 2015-2017 Member, National Health and Security Preparedness Analytic Methodology Working Group 2015 Chair, Public Health Services Research Student Scholarship Selection Committee 2015-2017 Member, University at Albany-SUNY Downstate Steering Committee on Health Disparities Research 2017 Visiting Scholar, Luskin School of Public Affairs, University of California Los Angeles 2016-2017 Member Consultant, National Committee on Vital and Health Statistics, Work Group on HHS Data Access and Use 2017-2018 Member, Injection Drug User Sentinel Event Workgroup, New York State Department of Health 2019 Grant Reviewer, Canadian Institutes of Health 2019Editorial Board, Journal of Public Health Management and Practice Professional Memberships AcademyHealth Association for Public Policy and Management New York State Academy for Public Administration Honors and Awards 1997-2001 Donovan Family National Scholar, Brown University 2001 Nominated to Sigma Xi Scientific Research Society 2001-2003 Dean’s Award full tuition scholarship, University of Michigan 2003 Student travel award, Society for Research on Nicotine and Tobacco 2009 Distinguished doctoral dissertation, Yale University Graduate School 2012-2013 Career, Leadership, and University Excellence Fellow, University at Albany-SUNY 2013 Public Health Practice-Based Research Network Scholarship for travel to AcademyHealth 2014-2017 Career Development Award, Robert Wood Johnson Foundation Public Health Services and Systems Research 2018 Recognition, University at Albany Celebration of Scholarship

C. Contributions to Science My full list of publications is available at: http://www.ncbi.nlm.nih.gov/sites/myncbi/161SiHGbGDFQc/bibliography/49317560/public/?sort=date&direction =ascending (1) Assessing Variation in State Policies and Their Public Health Effects I have documented interstate differences in policies to address important public health issues, including incentives to promote organ donation, the generosity of AIDS Drug Assistance Program drug formularies, and the implementation of the CDC’s recommendations for hepatitis C testing. The studies have highlighted how where one lives can have a profound influence on the ability to receive treatment for comorbid substance use or receive appropriate screening for viral hepatitis. The studies on organ donation policies demonstrated that most state policies have not increased organ donation rates and that better policy designs are needed. The organ donation research has been widely cited in mainstream media outlets, thereby raising awareness about this public health issue.

1. Martin EG, Barry CL. The adoption of mental health drugs on state AIDS Drug Assistance Program formularies. Am J Public Health 2011; 101(6): 1103-1109. PMCID PMC3093265 2. Martin EG, Wang K. Integrating substance abuse treatment into HIV care: missed opportunities in the AIDS Drug Assistance Program. J Acquir Immune Defic Syndr 622(4): 421-429. PMID 23202815 3. Martin EG, Norcott A, Khalid H, O’Connell DA. Implementing updating recommendations on screening for hepatitis C virus: translating federal guidance into state practice. J Public Health Manag Pract 2017; 23(2): 169-174. PMID 25905667 4. Chatterjee P, Venkataramani AS, Vijayan A, Wellen JR, Martin EG. The effect of state policies on organ donation and transplantation in the United States. JAMA Intern Med 2015; 175(8): 1323-9. PMID 26030386 (2) Describing Unexpected and Counterintuitive Effects of Public Health Policies I have described cases where implementing policies may not have the desired effect. After the Affordable Care Act was passed, I interviewed AIDS Drug Assistance Program managers and uncovered early concerns that states choosing not to expand Medicaid may be worse off if Ryan White funds are reduced due to a perception that HIV-infected individuals will have improved access to health insurance and treatment. When the ban on using federal funding for syringe exchange programs was temporarily repealed, we found that programs did not successfully acquire these funds and policy implementation gaps appeared to render federal support as primarily symbolic. However, not all policy changes have limited effectiveness; in contrast, a seemingly minor change to HIV policy (the US Preventive Services Task Force assigning an “A” grade to HIV testing in the general population) could in fact lead to major changes in how HIV testing could be financed.

1. Green TC, Martin EG, Bowman S, Mann M, Beltsky L. Life after the ban: an assessment of US syringe exchange programs’ attitudes about and early experiences with federal funding. Am J Public Health, 2012; 102(5): e9-e16. PMID 22420810 2. Martin EG, Meehan T, Schackman BR. AIDS Drug Assistance Programs: managers confront uncertainty and need to adapt as the Affordable Care Act kicks in. Health Aff 2013; 32(6): 1063-1071.

PMID 23733980 3. Martin EG, Strach P, Schackman BR. The state(s) of health: federalism and the implementation of healthcare reform in the context of HIV care. Public Administration Review 2013; 73(S1): S94-S105.

4. Martin EG, Schackman BR. Updating the HIV testing guidelines: a modest change with major consequences. New Engl J Med 2013; 368(10): 884-886. PMID 23425132 (3) Recommendations on How to Improve the Impact and Sustainability of Open Health Data As part of the government transparency movement, agencies at all levels are proactively releasing “open data” before they are requested; these are publicly accessible, easily discoverable through searchable open data web portals, with unlimited use and distribution rights, and in non-proprietary formats. Yet agencies receive limited guidance on how to release open data. I have used focus groups with researchers, a systematic review of the quality and usability of data offerings, and interviews with policymakers and practitioners from innovative jurisdictions to identify: early use cases; the data desired by public health researchers and practitioners; specific ways in which the data, metadata, and platforms could be improved to make the data more valuable; and ways to improve the sustainability and long-term impact of open health data initiatives. As a result of my

expertise, I was invited to be the staff writer for a report to the US Department of Health and Human Services secretary about how to maximize the value of HealthData.gov.

1. Martin EG, Helbig N, Shah NR. Liberating data to transform healthcare: New York’s open data experience. JAMA 2014; 311(24): 2481-2. PMID 25058079 2. Martin EG, Helbig N, Birkhead GS. Opening health data: what do researchers want? Early experiences with New York’s open health data platform. J Public Health Manag Pract 2015; 21(5): e1-7. PMID 25105279 3. Martin EG, Law J, Ran W, Helbig N, Birkhead GS. Evaluating the quality and usability of open data for public health research: a systematic review of data offerings on three open data platforms. J Public Health Manag Pract 2017; 23(4): e5-e13. PMID: 26910872 4. Martin EG, Begany GM. Opening government health data to the public: benefits, challenges, and lessons learned from early innovators. J Am Med Inform Assoc 2017; 24(2): 345-351. PMID: 27497796 (4) Providing Actionable Information for Evidence-Based Decisions about Health Policies During the Ryan White HIV/AIDS Program’s 2006 reauthorization, I analyzed the patterns of federal funding allocations to states, finding that allocation patterns were not consistent with political arguments about which states received more than their share, and that the structure of the federal allocation formula has led to stagnant funding distributions despite changes in need. A collaborative project with the New York State Department of Health on the Partner Services program for HIV and other sexually transmitted diseases found different times to process cases across diseases and geography; this information is critical for identifying the most efficient way to use scarce resources. A large evaluation study of a New York Medicaid waiver provided evidence for how these policy changes improved healthcare delivery and health information exchange. I developed a mathematical model of the New York State system of HIV testing and care to help the Department of Health tailor its implementation of the state’s recent HIV testing law; these findings were included in the Department of Health’s report to the governor. I am finishing a project to update the mathematical model to examine the population-level impact of broader set of policies related to the governor’s “Ending the Epidemic” initiative to help the state meet its HIV care targets by 2020.

1. Martin EG, Pollack HA, Paltiel AD. Fact, fiction, and fairness: resource allocation under the Ryan White CARE Act. Health Aff 2006; 25: 1103-1112. PMID 16835192 2. Martin EG, MacDonald RH, Smith LC, Gordon DE, Tesoriero JM, Laufer FN, Leung S-YJ, Rowe KA, O’Connell DA. Mandating the offer of HIV testing: simulating the epidemiological impact and resource needs. J Acquir Immune Defic Syndr 2015; 68 (Suppl 1): S59-67. PMID 25545496 3. Johnson BL, Tesoriero J, Feng W, Qian F, Martin EG. Cost analysis and performance assessment of partner services for human immunodeficiency virus and sexually transmitted diseases, New York State, 2014. Health Serv Res; 2017; 52(Suppl 2): 2331-2342. PMID 28799163 4. Rockefeller Institute of Government. Evaluation of New York’s federal-state health reform partnership (F-SHRP) Medicaid section 1115 demonstration. Albany, NY: Rockefeller Institute of Government, 2015. [role: co-principal investigator] D. Research Support Ongoing Research Support New York State Department of Health Weller (PI) 10/01/2016 – 09/30/2021 Independent Evaluation of the New York State Delivery System Reform Incentive Payment Program (DSRIP) This is an independent evaluation of New York’s DSRIP Medicaid waiver, the mechanism by which New York is implementing the Medicaid Redesign Team Waiver Amendment that restructures the healthcare delivery system to reduce avoidable hospital use.

Role: Co-investigator National Institute on Drug Abuse Garner (PI) 07/01/2018 – 06/30/2023 Identifying and Disseminating Substance, Treatment, Strategy (STS) Recommendations to AIDS Service Organizations This project develops stakeholder-driven Substance-Treatment-Strategy recommendations for improving substance use disorder integration within HIV/AIDS settings, and testing the incremental effectiveness of external facilitation to AIDS service organizations.

Role: Investigator

National Institute on Drug Abuse Garner (PI) 07/15/2014 – 07/30/2019 Substance Abuse Treatment to HIV Care (SAT2HIV) This project tests the effectiveness of a single-session motivational interviewing-based brief intervention to address comorbid substance use within HIV service settings, and tests the effectiveness of an organizationallevel implementation strategy to help facilitate its implementation and sustainability within these settings.

Role: Consultant Completed Research Support New York State Department of Health NU62PS003692-05-09 Martin (PI) 05/15/2017 – 12/31/2017 Describing New York’s Policy Response to Counteract the Opioid Overdose Epidemic This project uses key informant interviews with staff at multiple state agencies involved with the state’s opioid overdose prevention strategy to understand comprehensive programming, programmatic changes, implementation strategies, collaborations across agencies, and process outcomes.

Role: PI New York State Department of Health C030792 Martin (PI) 12/01/2015 – 05/31/2017 Modeling the End of AIDS in New York State This project aims to use mathematical modeling to simulate how the Ending the (AIDS) Epidemic policy initiative will affect HIV transmission and HIV testing and care outcomes in New York State.

Role: PI New York State Department of Health 5U52PS00369205 Martin (PI) 01/01/2016 – 12/31/2016 Documenting Patterns of HIV Prevention Funding to States This project develops a holistic understanding of the CDC’s domestic HIV prevention funding portfolio and 2015 allocations to states and metropolitan areas to improve New York’s ability to allocate state HIV prevention funding more equitably and efficiently to local jurisdictions.

Role: PI Office of the Asst. Sec. for Planning & Eval. HHSP2332015000771 Elkin (PI) 09/01/2015 – 08/01/2016 A Scan of the Status of States’ Integration of Human Services and Health Insurance Programs This project uses a national survey to assess state human service program agencies’ efforts to integrate affordable health insurance and human services programs as encouraged under the Affordable Care Act. Role: Investigator New York State Department of Health Martin (PI) 01/15/2015 – 12/31/2015 Surveying Drug User Health and Service Access at Upstate New York Syringe Exchange programs This project surveys four upstate New York syringe exchange programs to understand clients’ demographic, physical, and mental health; experience and satisfaction with the syringe exchange site; patterns of drug use; access to medical services; drug overdose experiences; and knowledge of New York’s Good Samaritan Law. Role: PI Robert Wood Johnson Foundation #71597 Martin & Birkhead (PI) 01/15/2014 – 01/14/2016 Building a Sustainable Open Data Ecosystem for Public Health Services and Systems Research This project aims to facilitate the release of open data that are fit for research through a systematic review of the quality and usability of open health datasets, qualitative research on agency staff’s perceived value of open data and lessons learned from releasing data, and a pilot data linkage project.

Role: Co-PI Robert Wood Johnson Foundation #71130 Martin & Tesoriero (PI) 07/15/2013 – 01/14/2015 Optimizing the Use of HIV/STD Partner Services Strategies in New York State This project quantifies statewide variation in the costs and staffing effort of delivering standard HIV/STD partner services, evaluates changes in costing and staffing effort to deliver high-impact HIV partner services, determines how reallocating staff resources from standard to high-impact partner services impacts costs and outcomes, and makes recommendations on when reallocating staff resources leads to efficiency gains.

Role: Co-PI

OMB No. 0925-0001 and 0925-0002 (Rev. 11/16 Approved Through 10/31/2018)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Morne, Johanne E. eRA COMMONS USER NAME (credential, e.g., agency login): POSITION TITLE: Director, AIDS Institute, New York State Department of Health EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION The College of St. Rose Albany, New York

DEGREE (if applicable)

Completion Date MM/YYYY

BS

1998

Social Work

BA

1998

Psychology

MS

2001

Education & Counseling

FIELD OF STUDY

A. Personal Statement I serve as Director of the New York State Department of Health AIDS Institute. I have been with the AIDS Institute for more than 12 years. The AIDS Institute was created in 1983 to coordinate the State’s overall response to the HIV epidemic. The AIDS Institute has broadened its mission by integrating hepatitis and sexually transmitted disease (STD) services, surveillance, drug user health, opioid overdose prevention, and non-HIV Lesbian, Gay, Bisexual, and Transgender (LGBT) services into its structure. The AIDS Institute is a $400 million public health program with a staff of more than 500. The AIDS Institute formulates policy related to HIV, hepatitis, sexually transmitted diseases (STDs), drug user health, and LGBT health and human services; initiates, develops, and evaluates programs for the delivery of HIV, hepatitis, and STD prevention, health care and supportive services as well as drug user health and LGBT health and human services; establishes clinical standards and oversees quality management; educates health care providers and the public; and guides regional and statewide planning. In its more than 35-year history, the AIDS Institute has provided leadership in New York State, at the national level, and internationally. Since 2013, I have worked closely with key stakeholders in implementing the Governor’s plan to end AIDS as an epidemic in New York State by the end of 2020. Since March 2018, I have worked closely with stakeholders in implementing the Governor’s strategy to eliminate hepatitis C virus in New York State by the end of 2030.

Prior to joining the State Health Department, I served as quality manager of psychiatry and HIV services at a Designated AIDS Center hospital and director of community-based HIV services at a federally qualified health center. My professional and clinical experience is in public health and behavioral health, particularly within communities of color.

B. Positions and Honors Positions: 2016-Present 2009-2016

New York State Department of Health, Albany, New York Director, AIDS Institute New York State Department of Health, Albany, New York 1

2007-2009 2007-2012 2007-2009

2005-2007 2001-2006 2004-2006 2003-2005

2000-2001 1999-2000 1995-1999

Director, Office of Planning and Policy/Office of Planning and Community Affairs (OPCA), AIDS Institute New York State Department of Health, Albany, New York Assistant Director, Bureau of Community Support Services, AIDS Institute Albany Medical Center (AMC), Albany, New York Crisis Prevention Instructor, Training University at Albany, Albany, New York Adjunct Professor Sociology Department (Capitalize on Community) Albany Medical Center (AMC), Albany, New York Quality Specialist, Quality Management Department Whitney M. Young Jr. Health Center, Albany, New York Program Director, HIV/AIDS Program Whitney M. Young Jr. Health Center, Albany, New York Program Director, Community Outreach Services Whitney M. Young Jr. Health Center, Albany, New York Clinical Supervisor, Outpatient Chemical Dependency Services Clinical Supervisor, Methadone Maintenance Treatment Program Whitney M. Young, Jr. Health Center, Albany, New York Program Director, Methadone Maintenance Treatment Program Whitney M. Young, Jr. Health Center, Albany, New York VOC/ED Coordinator, Methadone Maintenance Treatment Program Equinox, Inc., Albany, New York Client Services Coordinator Albany County Domestic Violence Program

Honors: May 2017 July 2012

National Alliance of State and Territorial AIDS Directors (NASTAD) Chair’s Challenge Award for Ending Epidemics In Our Own Voices Community Advocacy Award

C. Contributions to Science Since 2013, I have provided leadership and worked with the community on the State’s Ending the Epidemic (ETE) initiative, with the goal of ending the AIDS epidemic in New York State by the end of 2020. This effort has involved a government-community partnership, which led to the establishment of the ETE Blueprint, publicly released on April 29, 2015, developed by a task force of key stakeholders representing public entities, private industry, providers, consumers, community leaders and advocates. The State’s ETE goals include identifying persons who are unaware of their status and linking them to care and treatment; linking persons with HIV to care and treatment to improve their health, achieve viral suppression, and prevent further transmission; and facilitating access to pre-exposure prophylaxis (PrEP) for persons at risk to keep them negative. Policy and program interventions have been employed to reach ETE goals, including modifying policy to streamline HIV testing, facilitate access to syringe exchange, enable minors to consent for HIV prevention and care services, expand data sharing to facilitate linkage to care, and expand access to affordable housing for persons with HIV. Program initiatives have been implemented to expand access to preexposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) and facilitate linkage to care and rapid treatment for persons with HIV. The ETE initiative is having an impact.

• • • •

New diagnoses in 2018 reached an all-time low of 2,481 - an 11 percent drop from 2017 and a 28 percent drop since 2014. By comparison, diagnoses decreased by 3.9 percent from 2016 to 2017.

The decrease in new HIV diagnoses was observable across every demographic group.

2018 saw the fourth straight annual decrease in new diagnoses among gay, bisexual, and other men who have sex with men, after little change in over a decade.

From 2014 to 2017, the last year of available data, estimated new HIV infections decreased from 3,273 to 2,269, a 31% reduction.

2

• • • • •

Data show almost 32,000 New Yorkers took Pre-Exposure Prophylaxis, or PrEP, in 2018 - an increase of 32 percent from 2017.

Data show unprecedented progress in the percentage of newly diagnosed persons linked to care within 30 days of their diagnosis – 81 percent.

The percentage of persons living with diagnosed HIV receiving any care continues to increase and exceeds 80 percent.

Eighty-seven percent of persons living with diagnosed HIV in care are virally suppressed.

Once again, in 2018, New York State eliminated mother-to-child transmission of HIV, with no transmissions. New York State has met CDC’s elimination goals for four consecutive years.

Notably, the State issued an aggressive Rapid Initiation of Antiretroviral Treatment policy. The gold standard is initiation of treatment on the same day as diagnosis. The policy supports the “Undetectable equals Untransmittable” (U=U) message that people with a sustained undetectable viral load cannot sexually transmit HIV. In July 2018, Governor Cuomo announced the nation's first strategy to eliminate hepatitis C and the establishment of a Hepatitis C Elimination Task Force to advise the State on its hepatitis C elimination plan.

The elimination effort aims to stop the spread of the virus by expanding programs to connect New Yorkers with prevention, screening, and treatment services and enhancing hepatitis C surveillance. The Task Force was charged with updating the recommendations of the 2017 community consensus statement on elimination of hepatitis C in New York State. The State has moved toward elimination of hepatitis C. •

•

•

•

The New York State hepatitis C testing law requires the offer of a hepatitis C test to persons born between 1945 and 1965 receiving hospital and primary care. The law led to a marked increase in the number of hepatitis C screening tests and screening rates.

The Hepatitis C Elimination Task Force has drafted recommendations on the hepatitis C elimination plan.

Funding in the amount of $5 million was appropriated in the 2018-19 State budget for hepatitis C elimination. The funding supports: o The Hepatitis C Criminal Justice Initiative – an expansion of the HIV Criminal Justice Initiative.

The expansion supports reentry services and peer education for incarcerated persons living with hepatitis C, including those on hepatitis C treatment at the time of release. o The Hepatitis C Patient Navigation Program at seven upstate Drug User Health Hubs. The Hepatitis C Patient Navigation Program aims to increase the number of people who inject drugs who know their hepatitis C status and are linked to medical care and treatment. o Three innovative hepatitis C care and treatment models that address the needs of persons with hepatitis C who inject drugs. o The Hepatitis C Rapid Testing Program, which provides testing supplies for programs enrolled in the program. o Expanded hepatitis C care and treatment programs. o Hepatitis C surveillance infrastructure. o Research on hepatitis C in persons who inject drugs (PWID). o A statewide hepatitis C multi-media awareness campaign.

In 2017, 7,474 NYS Medicaid members were treated with a Direct Acting Antiviral at a cost of $382,771,724.

D. Additional Information: Research Support and/or Scholastic Performance 2007-2014 2013 2007 2001

Certified Crisis Prevention Institute Instructor Graduate - National Alliance of State and Territorial AIDS Directors (NASTAD) Minority Leadership Program NYS Certification in Liberal Arts Education Chi Sigma Iota, Counseling, Academic And Professional Honor Society

Additional Professional Activity 3

▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪

Board Chair, 2019-2020, National Alliance of State and Territorial AIDS Directors (NASTAD) Board Member, National Alliance of State and Territorial AIDS Directors (NASTAD) Albany County Medical Reserve Corps Volunteer 2001 – 2006 Co-Chair of the NENY Ryan White HIV Network Steering Committee Clinical Supervisor of community-based HIV prevention series based groups 2004-2007 Board Member of the Albany Damien Center 2001- 2007 Executive Board Member of the NYS Committee of Methadone Program Administrators, Field Placement Supervisor for Social Work and related fields of study at College of St. Rose, University at Albany, Hudson Valley Community College Academic tutor in general subjects and language Community volunteer

Trainings Facilitated ▪ Crisis Intervention /Conflict Resolution ▪ Motivational Interviewing Skills ▪ Domestic Violence: Power and control in our lives, Domestic Violence Institutional policy and procedure ▪ HIV/AIDS: the 101 guide, HIV and DV: what do we have in common, HIV and over 50: we’re all affected ▪ Stress management versus time management ▪ Applying theory to practice in the middle of the day ▪ Life skills workshop series ▪ Culture, competence and diversity ▪ Health Care in the streets: the mobilization of treatment ▪ Coming to your community: the use of a Mobile health unit for hard to reach populations ▪ Management versus leadership: a dual diagnosis ▪ Harm Reduction in your professional life ▪ HIPAA Compliance within health care ▪ Trans-theoretical Model of Change: not just a line in the service plan ▪ Team Building and Group Psychology 101

4

OMB No. 0925-0001 and 0925-0002 (Rev. 10/15 Approved Through 10/31/2018)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Tesoriero, James M. eRA COMMONS USER NAME (credential, e.g., agency login): james.tesoriero@health.ny.gov POSITION TITLE: Director, Division of HIV/STD Epidemiology, Evaluation and Partner Services, AIDS Institute, NYS Department of Health EDUCATION/TRAINING INSTITUTION AND LOCATION

DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

State University of New York College at Oswego

B.A.

1987

Sociology

Northeastern University

M.S.

1988

Criminal Justice

State University of New York at Albany

Ph.D.

1998

Criminology

A. Personal Statement I have worked at the New York State (NYS) Health Department for 26 years. My experience positions me well for my role in this project, which is to ensure that Georgian Ph.D. students are provided field placement and mentoring opportunities that translate research and evaluation activities into real-world programming, particularly as it relates to efforts to end the AIDS Epidemic in NYS. I am currently the Director of the Division of HIV/STD Epidemiology, Evaluation and Partner Services at the Health Department’s AIDS Institute. In this capacity, I oversee HIV and STD surveillance and partner services for NYS. I also oversee the Office of Program Evaluation and Research, which is dedicated to ensuring the State’s HIV/STD/HCV, LGBT and drug user health programming are employing evidence-based best practice. Prior my current position, I was the Director of HIV/STD/HCV Prevention for NYS. As Prevention Director, I oversaw 75 million dollars in statewide initiatives dedicated to HIV testing and linkage to care, HIV and STD partner services, condom promotion and distribution, behavioral interventions for HIV positive and high-risk individuals, LGBT health, drug user health including syringe access and overdose prevention, and various policy initiatives designed to remove barriers to effective HIV programming. My current and former divisions are heavily involved in the State’s efforts to end AIDS as an epidemic in NYS. I have mentored many MPH and Ph.D student interns over my 26 years at the NYS Health Department. I have also been Principal Investigator on several block and competitive grants and I have published numerous papers in peer-reviewed literature on HIV/AIDS. I have overseen several Statemandated evaluations of new initiatives, laws, and programming. I am well suited for my role in this project.

My current research focuses on maximizing New York State’s Partner Services-led initiatives, including datato-care, molecular epidemiology, and those within the NYS prison system.

B. Positions and Honors Positions and Employment (Selected) 1992-1998 Research Specialist (I, II, and III), Office of Program Evaluation and Research, New York State Department of Health, AIDS Institute, Albany, NY 1998-2010 Director, Office of Program Evaluation and Research, New York State Department of Health, AIDS Institute, Albany, NY 2010- 2012 Associate Director, Division of HIV/STD/HCV Prevention, New York State Department of Health, AIDS Institute, Albany, NY

2001-2012 2012-2016

Member, NYS Department of Health Institutional Review Board Director, Division of HIV/STD/HCV Prevention, New York State Department of Health, AIDS Institute, Albany, NY 2016-Present Director, Division of HIV/STD Epidemiology, Evaluation and Partner Services, New York State Department of Health, AIDS Institute, Albany, NY 2012-Present Chair, NYS Department of Health Institutional Review Board 2018-Present Clincial Associate Professor, School of Public Health, Department of Health Policy, Management and Behavior, State Univeristy of New York at Albany

Honors 1987 1996 2001 2012 2012 2012 2014 2015 2015 2015 2016 2016

Seward Salisbury Award for Outstanding Senior in Sociology – SUNY College at Oswego Elliot Lumbard Award for Distinguished Ph.D. Candidate – SUNY at Albany NYSDOH Commissioner’s Recognition Award. Expanded Syringe Access Program Team NYSDOH Commissioner’s Recognition Award. Aging, Sexual Health and HIV/Hepatitis C Team NYSDOH Commissioner’s Recognition Award. NYS HIV Testing Law Evaluation Team NYSDOH Commissioner’s Recognition Award. Prevention Agenda 2012 Team NYSDOH Commissioner’s Recognition Award. Bridging Public Health and Public Safety Team NYSDOH Commissioner’s Excellence Award. DOH Institutional Review Board (IRB) Team NYSDOH Commissioner’s Excellence Award. Opioid Overdose Prevention Team NYSDOH Commissioner’s Excellence Award. NYS HIV Algorithm Implementation Team NYSDOH Commissioner’s Excellence Award. JAIDS 2015 Supplement Team NYSDOH Commissioner’s Excellence Award. Data to Care Program Team

C. Contribution to Science Reducing the Number Undiagnosed HIV Infections Nationally, an estimated 15% of persons living with HIV/AIDS are undiagnosed. The National HIV/AIDS Strategy has set a goal of reducing this to 10% by the year 2020. Thanks to significant state funding and cutting edge HIV prevention programming, NYS has already reached this target, with an estimated 92% of PLWH diagnosed by 2016. Throughout my 26 years at the AIDS Institute, I have been heavily involved in efforts to increase HIV testing to targeted communities, including pregnant women, incarcerated persons, injection drug users, and communities of color. Much of this work entailed combating HIV-related stigma among affected communities to embrace the public health benefits of testing. Since 2010 I have also focused on efforts to routinize HIV testing in primary care settings, by changing Public Health Law to require and promote HIV testing, through targeted and generalized HIV testing campaigns, and through quality reviews of hospital HIV testing protocols and practices.

1. Elkington KS, Jaiswal J, Spector AY, Reukauf H, Tesoriero JM, Nash D, Remien RH. Can TasP Approaches Be Implemented in Correctional Settings?: A review of HIV testing and linkage to community HIV treatment programs. J Health Care Poor Underserved. 2016;27(2A):71-100. doi: 10.1353/hpu.2016.0047. PubMed PMID: 27133513.

2. Tesoriero JM, Battles HB, Heavner K, Leung SY, Nemeth C, Pulver W, Birkhead GS. The effect of name-based reporting and partner notification on HIV testing in New York State. Am J Public Health.

2008 Apr;98(4):728-35. doi: 10.2105/AJPH.2007.092742. PubMed PMID: 18356570.

3. Wade NA, Birkhead GS, Warren BL, Charbonneau TT, French T, Wang L, Baum J, Tesoriero J, Savicki R. Abbreviated Regimens of Zidovudine Prophylaxis and Perinatal Transmission of the Human Immunodeficiency Virus. New England Journal of Medicine. 1998; 339(20): 1409-14. PMID: 9811915 4. Tesoriero JM, Sorin MD, Burrows KA, LaChance-McCullough ML. Harnessing the heightened public awareness of celebrity HIV disclosures: "Magic" and "Cookie" Johnson and HIV testing. AIDS Educ Prev. 1995 Jun;7(3):232-50. PubMed PMID: 7646947.

Implementing Best Practice Implementation Science is the study of methods to promote the adoption of evidence-based practices, interventions and policies into routine public health and health care settings. In my capacity as Director of Research for the AIDS Institute, helping program and policy officials translate evidence based research into practice was a central portion of my focus for over a decade. I routinely led efforts to adapt, translate and evaluate the real-world applications of evidence based interventions. As HIV Prevention Director, I focused on testing and scaling up successful pilot initiatives. Most recently I led efforts to develop, pilot, and expand the use of HIV surveillance data and partner service programming to identify, locate, and reengage HIV positive persons back to HIV-related medical care.

1. Tesoriero JM, Johnson BL, Hart-Malloy R, Cukrovany JL, Moncur BL, Bogucki KM, Anderson BJ, Johnson MC. Improving Retention in HIV Care Through New York's Expanded Partner Services Datato-Care Pilot. J Public Health Manag Pract. 2017 May/Jun;23(3):255-263. doi: 10.1097/PHH.0000000000000483. PubMed PMID: 27902561; PubMed Central PMCID: PMC5381495 2. Exner TM, Tesoriero JM, Battles HB, Hoffman S, Mantell JE, Correale J, Adams-Skinner J, Shapiro DA, Rowe K, Cotroneo RA, Leu CS, Hunter J, Klein SJ. A randomized controlled trial to evaluate a structural intervention to promote the female condom in New York state. AIDS Behav. 2012 Jul;16(5):1121-32. doi: 10.1007/s10461-012-0176-3. PubMed PMID: 22484992; PubMed Central PMCID: PMC3918419.

3. French T, Tesoriero J, Agins B. Changes in stress, substance use and medication beliefs are associated with changes in adherence to HIV antiretroviral therapy. AIDS Behav. 2011 Oct;15(7):141628. doi: 10.1007/s10461-010-9762-4. PubMed PMID: 20640593.

4. Tesoriero J, French T, Weiss L, Waters M, Finkelstein R, Agins B. Stability of adherence to highly active antiretroviral therapy over time among clients enrolled in the treatment adherence demonstration project. J Acquir Immune Defic Syndr. 2003 Aug 1;33(4):484-93. PubMed PMID: 12869837.

Preventing HIV Infection The bolus of my research and evaluation experience has focused on the general areas of HIV prevention.

Specific areas, in addition to those noted above, have included expanding the role of faith communities in HIV prevention, particularly among communities of color, identifying interventions to improve health and prevent secondary transmission among HIV positive individuals, assessing the impact of public health law (and its implementation) on HIV prevention, and expanding access to sterile syringes among injection drug users.

1. Tesoriero JM, Gieryic SM, Carrascal A, Lavigne HE. Smoking among HIV positive New Yorkers: prevalence, frequency, and opportunities for cessation. AIDS Behav. 2010 Aug;14(4):824-35. doi: 10.1007/s10461-008-9449-2. PubMed PMID: 18777131.

2. Tesoriero JM, Battles HB, Klein SJ, Kaufman E, Birkhead GS. Expanding access to sterile syringes through pharmacies: assessment of New York's Expanded Syringe Access Program. J Am Pharm Assoc 2009 May-Jun;49(3):407-16. doi: 10.1331/JAPhA.2009.07127. PubMed PMID: 19443321.

3. Cason C, Orrock N, Schmitt K, Tesoriero J, Lazzarini Z, Sumartojo E. The impact of laws on HIV and STD prevention. J Law Med Ethics. 2002 Fall;30(3 Suppl):139-45. PubMed PMID: 12508517.

4. Tesoriero JM, Parisi DM, Sampson S, Foster J, Klein S, Ellemberg C. Faith communities and HIV/AIDS prevention in New York State: results of a statewide survey. Public Health Rep. 2000 NovDec;115(6):544-56. PubMed PMID: 11354338; PubMed Central PMCID: PMC1308626.

A complete list of my published work is available at MYBibliography: https://www.ncbi.nlm.nih.gov/sites/myncbi/18Uf7XMVehcAC/bibliography/52721230/public/?sort=date&directio n=ascending.

D1. Research Support (Past 3 Years) NU62PS924514 Tesoriero (PI) $417,927/Year CDC High Impact HIV Molecular Epidemiology

2018-2022

Through a combination of high impact data-to-care strategies based on analysis of routinely collected HIV nucleotide sequence data, multi-sector statewide collaborations that reflect the population’s interjurisdictional mobility patterns, innovative approaches to HIV testing, both generalized and targeted PrEP training for clinicians and their staff, and ongoing monitoring and quality improvement activities, NYSDOH is implementing a statewide High Impact HIV Molecular Epidemiology program. The program is designed to reduce new HIV infections and diagnoses, increase the percentage of HIV-infected persons who are aware of their status and engaged in care, increase PrEP coverage and adherence, increase genotype sequencing, improve rates of viral suppression, and identify and prioritize identified social-structural barriers that impede Hispanic/Latino MSM participating in HIV-related services.

NU62PS924546 Tesoriero (PI) $1,895,697/Year CDC High Impact Prevention and Surveillance Project (HIPS)

2018-2021

HIPS is a statewide initiative designed to reach persons at highest risk for HIV/STDs by engaging persons who are part of Health Department surveillance-identified risk networks to become (Social Network Strategy (SNS) recruiters. HIPS identifies identifies peer recruiters from patients who are part of Partner Servies investigations for HIV and other sexually transmitted infections. Eligible recruiters are linked to partnering community based organizations responsible for training, orientation, and supervision, implementing SNS cycles, and reporting data to NYSDOH to inform program evaluation and cluster investigations.

U62004513 Tesoriero (PI) $644,683/Year CDC New York State High Impact Care and Prevention Project

2014-2018

The purpose of this project is to improve collaboration among CDC-funded state health departments and HRSA-funded health centers to expand the provision of HIV prevention and care services within communities most impacted by HIV, especially racial/ethnic minorities, and to better serve PLWH. This project seeks to develop and implement effective, replicable, and sustainable programmatic models for collaborating with health centers located in high HIV prevalence jurisdictions, to increase health centers’ capacity to deliver HIV prevention and care activities, improve the identification of undiagnosed HIV infection, establish new access points for HIV care and treatment, and improve HIV outcomes along the continuum of care for PLWH. 71130 Tesoriero (PI) $150,000 Robert Wood Johnson Foundation NY PHPBRN Public Health Delivery and Cost Studies

2013-2015

With CDC policy initiatives emphasizing high impact HIV/STD prevention activities, public health decision makers need to understand both the costs of such activities and their relationship to outcomes, to ensure optimal allocation of labor and resources. This study will conduct an economic assessment of HIV/STD partner services (PS) delivery by state and local public health agencies. The research is measuring variation across two strategies: 1) traditional PS focused on newly diagnosed infections; and 2) on-going PS for HIV infected individuals who have been identified as being out of medical care. This comparision will reveal how reallocating staff resources to the new, high impact strategy affects the costs and outcomes of the PS programs at the state and county levels.

1U62PS003692 Tesoriero (PI) $931,950/Year CDC Positive Pathways: An Intervention to Identify New and Existing HIV Infections in Prison and Promote HIV Treatment and Continuity of Care upon Release

2012-2015

The Positive Pathways Project is a unique collaboration between the NYSDOH AIDS Institute, the NYS Department of Corrections and Community Supervision (DOCCS), the HIV Center at Columbia University and five community based organizations already providing services in NYS prisons. Using funding from a CDC grant starting in 2012, these groups are working together to reduce HIV stigma, identify and treat HIV positive inmates in correctional facilities, and ensure linkage to care and treatment adherence upon and after release.

D2. Other Support (Past 3 Years) 5U62PS003692-05 Tesoriero (PI) $14,214,675/Year 2012-2017 CDC Comprehensive HIV Prevention for Health Departments This CDC block grant funds core HIV prevention for New York state. Primary programmatic areas include HIV testing, comprehensive prevention with positives, condom distribution, policy initiatives, evidence based interventions targeted to high risk persons, jurisdicational planning, social media and marketing, and monitring and evaluation.

Karen Hagos, MPH Karen is currently the Director of the Office of Planning and Community Affairs (otherwise known as “OPCA”) within the New York State Department of Health’s AIDS Institute. Her office is responsible for ongoing, cross-programmatic policy development, strategic planning, budgetary and legislative analyses as well as the management support and administration of several advisory bodies. The Office also leads the coordination of efforts aimed at ending the AIDS epidemic in New York State.

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Holtgrave, David R. eRA COMMONS USER NAME (credential, e.g., agency login): DHoltgr1 POSITION TITLE: Dean and Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION University of Missouri at St. Louis University of Illinois at Urbana/Champaign Harvard University School of Public Health, MA

DEGREE (if applicable)

Completion Date MM/YYYY

BA

08/1983

Psychology

PhD

01/1988

Quantitative Psychology

PostDoc

07/1989

Environmental Health, Public Policy (Interdisciplinary Programs in Health

FIELD OF STUDY

A. Personal Statement David Holtgrave, PhD, has served as the Dean of the School of Public Health, University at Albany, State University of New York since March 2018. He is also appointed as a SUNY Empire Innovation Professor.

From August 2005 through February 2018, David served as Professor and Chair of the Department of Health, Behavior and Society at the Johns Hopkins Bloomberg School of Public Health. In July 2017, he was appointed to hold the Inaugural Health, Behavior and Society Professorship (an endowed professorship). He also held joint appointments in the Johns Hopkins schools of medicine and nursing.

Dr. Holtgrave has worked extensively in the field of HIV prevention since 1991. His research has focused on the effectiveness and cost-effectiveness of HIV prevention interventions and the translation of those study findings to HIV prevention policy. Dr. Holtgrave previously served as member and then vice-chair of the Presidential Advisory Council on HIV/AIDS during President Obama’s Administration, and testified before the U.S. House of Representatives during Representative Henry Waxman’s hearing on domestic HIV Prevention in 2008.

Prior to his position at Johns Hopkins University, Dr. Holtgrave was a professor at the Rollins School of Public Health at Emory University. He also served as director of the Division of HIV/AIDS Prevention – Intervention Research and Support at the U.S. Centers for Disease Control and Prevention (CDC), as well as on the faculty at the Center for AIDS Intervention Research at the Medical College of Wisconsin. He has authored or coauthored over 300 professional publications. He edited The Handbook of Economic Evaluation for HIV Prevention Programs (Plenum Press, 1998). Along with a number of colleagues from AIDS United and Johns Hopkins University, he is a co-author of the book, “Improving Access to HIV Care: Lessons from Five U.S. Sites” (Johns Hopkins University Press.

1. Holtgrave DR, Hall HI, Wehrmeyer L, Maulsby C. Costs, consequences and feasibility of strategies for achieving the goals of the National HIV/AIDS strategy in the United States: a closing window for success?. AIDS Behav. 2012 Aug;16(6):1365-72. PubMed PMID: 22610372.

2. Hall HI, Frazier EL, Rhodes P, Holtgrave DR, Furlow-Parmley C, Tang T, Gray KM, Cohen SM, Mermin J, Skarbinski J. Differences in human immunodeficiency virus care and treatment among

subpopulations in the United States. JAMA Intern Med. 2013 Jul 22;173(14):1337-44. PubMed PMID: 23780395.

3. Holtgrave DR, Kim JJ, Adkins C, Maulsby C, Lindsey KD, Johnson KM, Montoya DC, Kelley RT. Unmet HIV service needs among Black men who have sex with men in the United States. AIDS Behav. 2014 Jan;18(1):36-40. PubMed PMID: 23892769.

4. Holtgrave DR. Development of year 2020 goals for the National HIV/AIDS Strategy for the United States. AIDS Behav. 2014 Apr;18(4):638-43. PubMed PMID: 23934340.

B. Positions and Honors 1989 - 1991 1991 - 1995 1995 - 1997 1997 - 2001 2001 - 2005 2005 2018 -

Assistant Professor, UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER (Department of Family Medicine) Behavioral Scientist, CENTERS FOR DISEASE CONTROL AND PREVENTION (National Center for Prevention Services, and Office of the Associate Director of HIV/AIDS, CDC) Associate Professor, MEDICAL COLLEGE OF WISCONSIN (Center for AIDS Research) Director, CENTERS FOR DISEASE CONTROL AND PREVENTION (Division of HIV/AIDS Prevention -- Intervention Research and Support) Professor, EMORY UNIVERSITY (Rollins School of Public Health) Professor and Department Chair, JOHNS HOPKINS UNIVERSITY (Bloomberg School of Public Health, Department of Health, Behavior & Society) Dean, School of Public Health, and Professor, Department of Health Policy, Management and Behavior, UNIVERSITY AT ALBANY, STATE UNIVERSITY OF NEW YORK

Other Experience and Professional Memberships Member, American Public Health Association Membr, Society for Medical Decision Making

Honors Appointed Member and Vice-Chair, Presidential Advisory Council on HIV/AIDS The Golden Apple Award and The Johns Hopkins University Alumni Association Excellence in Teaching Award, Johns Hopkins Bloomberg School of Public Health Positive Leadership Award, National Association of People with AIDS Partnership Award, National Alliance of State and Territorial AIDS Directors C. Everett Koop National Health Award, The Health Project

C. Contributions to Science 1. I have conducted cost-effectiveness and cost-utility analyses of a number of public health interventions.

This worked has focused most pointedly on HIV prevention and care programs, with a secondary emphasis on smoking-related interventions. The studies help inform program managers and policy makers about the cost and relative cost-effectiveness of a variety of public health services. a. Holtgrave DR, Wunderink KA, Vallone DM, Healton CG. Cost-utility analysis of the National truth campaign to prevent youth smoking. Am J Prev Med. 2009 May;36(5):385-8. PubMed PMID: 19211214. b. Holtgrave DR, Maulsby C, Kharfen M, Jia Y, Wu C, Opoku J, West T, Pappas G. Cost-utility analysis of a female condom promotion program in Washington, DC. AIDS Behav. 2012 Jul;16(5):1115-20.

PubMed PMID: 22434283. c. Villanti AC, Curry LE, Richardson A, Vallone DM, Holtgrave DR. Analysis of media campaign promoting smoking cessation suggests it was cost-effective in prompting quit attempts. Health Aff (Millwood). 2012 Dec;31(12):2708-16. PubMed PMID: 23213155.

d. Holtgrave DR, Wolitski RJ, Pals SL, Aidala A, Kidder DP, Vos D, Royal S, Iruka N, Briddell K, Stall R, Bendixen AV. Cost-utility analysis of the housing and health intervention for homeless and unstably housed persons living with HIV. AIDS Behav. 2013 Jun;17(5):1626-31. PubMed PMID: 22588529.

2. In partnership with key policy makers and program managers, I have conducted a number of resource allocation modeling projects which serve to provide guidance on how best to allocate resources across an array of available program options. These studies have been done on both very high and low HIV prevalence jurisdictions, and have served to directly inform the prioritization of uses of resources in these settings. a. Holtgrave DR, Hall HI, Wehrmeyer L, Maulsby C. Costs, consequences and feasibility of strategies for achieving the goals of the National HIV/AIDS strategy in the United States: a closing window for success?. AIDS Behav. 2012 Aug;16(6):1365-72. PubMed PMID: 22610372. b. Holtgrave DR, Young PA, Mayer RR, Maulsby C, Kim JJ. Employing resource allocation modeling to inform HIV prevention planning for the state of Iowa. AIDS Educ Prev. 2013 Oct;25(5):423-9. PubMed PMID: 24059879. c. Holtgrave DR, Kim JJ, Adkins C, Maulsby C, Lindsey KD, Johnson KM, Montoya DC, Kelley RT. Unmet HIV service needs among Black men who have sex with men in the United States. AIDS Behav.

2014 Jan;18(1):36-40. PubMed PMID: 23892769. d. Holtgrave DR. Development of year 2020 goals for the National HIV/AIDS Strategy for the United States. AIDS Behav. 2014 Apr;18(4):638-43. PubMed PMID: 23934340.

3. Along with key colleagues specializing in HIV surveillance and epidemiology, I have contributed to studies which helped define the concept of HIV transmission rates for the U.S., and to estimate these transmission rates for a number of key populations (such as persons living with HIV who are aware and unaware of HIV seropositivity). Related to this work is research into trends in HIV testing and diagnoses in the U.S. a. Hall HI, Holtgrave DR, Maulsby C. HIV transmission rates from persons living with HIV who are aware and unaware of their infection. AIDS. 2012 Apr 24;26(7):893-6. PubMed PMID: 22313960. b. Hall HI, Holtgrave DR, Tang T, Rhodes P. HIV transmission in the United States: considerations of viral load, risk behavior, and health disparities. AIDS Behav. 2013 Jun;17(5):1632-6. PubMed PMID: 23456577. c. Holtgrave DR, Hall HI, Des Jarlais DC, Mizuno Y, Purcell DW. Estimating number of diagnosed persons living with HIV in the United States engaged in unprotected serodiscordant risk behavior with unsuppressed viral load. J Acquir Immune Defic Syndr. 2014 Mar 1;65(3):e125-8. PubMed PMID: 23978998. d. Johnson AS, Hall HI, Hu X, Lansky A, Holtgrave DR, Mermin J. Trends in diagnoses of HIV infection in the United States, 2002-2011. JAMA. 2014 Jul 23-30;312(4):432-4. PubMed PMID: 25038362.

D. Additional Information: Research Support and/or Scholastic Performance Ongoing Research Support 2016/01/16-2019/06/30 Truth Initiative Holtgrave, David Johns Hopkins MOU: Cost Analysis The purpose of this analysis is to assess the overall cost of the implementation of the truth “Finish It” campaign Role: Principal Investigator 2014/10/01-2019/09/30 T28830, CDC: Emory University DOWDY, DAVID (PI) Enhancing Models of HIV, Viral Hepatitis, STI’s and Tuberculosis to Inform and Improve Public Health Impact

The goal of this five-year project is to assist the United States Centers for Disease Control and Prevention in their approach to modeling HIV and other infectious disease Role: Co-Investigator 2014/09/15-2019/06/30 14129929, USAID: Population Council KERRIGAN, DEANNA (PI) Project SOAR (Supporting Operational AIDS Research) Project SOAR is a global initiative to improve HIV and AIDS program outcomes through strengthened operational research and evaluation activities.

Role: Co-Investigator 2014/09/01-2019/08/31 Philanthropic Gift, Mr. Sid and Ms. Helaine Lerner HOLTGRAVE, DAVID R (PI) Lerner Center for Public Health Promotion Establish center to support health promotion projects in the U.S. Role: PI 2018/09/01-2023/08/31 1R01MH114847 University of Illinois (NIH) ALBARRACIN, DOLORES (PI) Mining social media messages for HIV testing and prevention communication.

Role: Co-Investigator

Completed Research Support 2012/09/01-2018/04/30 P30AI094189, NIAID CHAISSON, RICHARD (PI) The Johns Hopkins Center for AIDS Research (JHU CFAR) CFAR helps to coordinate, mobilize the substantial scientific, clinical and public health resources at JHU to generate new knowledge to understand, respond to, and control the HIV pandemic.

Role: Co-Investigator 2009/02/01-2018/12/31 90061572, Bloomberg Philanthropies Joanna Cohen (PI) Bloomberg Worldwide Stop Smoking Initiative Efforts to monitor exposure to tobacco smoke and delineating, promoting, and evaluating the implementation of best practices in tobacco control.

Role: Co-Investigator 2016/01/01-2018/10/31 ACQUAL II Susan Krenn (PI) Family Planning Demand Creation in Kinshasa and Kongo Central, Democratic Republic of the Congo (DRC).

Dr. Holtgrave’s role on this project is to lead cost-effectiveness expertise.

2012/06/07-2017/03/31 2000 G QF123, NIMH: UCLA HOLTGRAVE, DAVID R (PI) Implementing Eban II: An Evidence-Based Intervention for Sero-Discordant Couples The implementation of Eban II is a 5-year study, an evidence-based risk reduction intervention for heterosexual, African American HIV serodiscordant couples, investigating the processes and determinants of

implementation in 10 community-based organizations (CBOs) in California, and real-world effectiveness of Eban II as it is delivered to 180 couples. Our subcontract examines the cost-effectiveness of this intervention.

Role: PI 2015/09/01-2016/12/31 University of Illinois at Urbana Chapaign HOLTGRAVE, DAVID R (PI) Online media and structural influences on new HIV/STI cases in the US (2006-2020) Conducted large-scale data mining of online social media, including Twitter, online dating sites, and discussion boards, and used the data in the development of models that predict where risk environments for HIV/STI transmission may emerge Role: PI 2013/01/01-2016/12/31 90054784, AIDS United Catherine Maulsby (PI) Access to Care (A2C) Social Innovation Fund (SIF2) This study trained Social Innovation Fund Year two (SIF2) grantees in all aspects of the national evaluation.

Role: Co-Investigator 2006/10/01-2016/12/30 H070203, American Legacy Foundation HOLTGRAVE, DAVID R (PI) Legacy Foundation / Johns Hopkins University Memo of Understanding The main goals of the project are to conduct cost effectiveness analyses of anti-smoking prevention succession campaigns and to help support Legacy’s Schroeder Institute for Tobacco Research.

Role: PI 2013/01/01-2016/06/30 90054915, AIDS United HOLTGRAVE, DAVID R (PI) Retention in Care Evaluation (RIC) We provided ongoing program evaluation technical assistance to help grantees finalize their local evaluation plans and to troubleshoot local evaluation questions as they arise throughout the project.

Role: PI 2008/01/01-2016/03/31 Philanthropic Gift, Johnson and Johnson HOLTGRAVE, DAVID R (PI) J&J Scholars Program Provided support for graduate students to work on program evaluation activities with community-based health care providers on topics such as childhood obesity and diabetes Role: PI

Alvaro Carrascal, MD, MPH, Assistant Emeritus Professor, Department of Epidemiology and Biostatistics, worked for 23 years at the AIDS Institute/New York State Department of Health serving in multiple capacities, including Deputy Medical Director and Director of the Division of HIV and Hepatitis Health Care. Most recently he worked as consultant for the AIDS Institute (2017-2018) providing technical/scientific support in the implementation of Undetectable Equals Untransmittable (U=U) initiative and the internal workgroup assessing public health impact of the potential legalization of marihuana in New York. He worked as Vice President of Cancer Control/Health Systems for the American Cancer Society, Eastern Division (ACS), responsible for overseeing the implementation of cancer control initiatives in New York and New Jersey through partnerships with health systems (community health centers/FQHCs, health plans, hospitals) and with State and City health departments. He was also Chair of the New York State Tobacco Use Prevention and Control Advisory Board and a member of the Steering Committee of the New York State Cancer Consortium.

Additional academic experiences include Adjunct Professor, Albany College of Pharmacy and Health Sciences (2017-18) and Visiting Professor Universidad de Costa Rica School of Public Health.

Areas of Involvement.

Strategic Priority A. Item 2. Expanding means for collaboration and exchange of ideas though hosting seminar series, journal club. Item 3. Employ social media strategy to disseminate research through publication of impactful products.

Strategic Priority B. Item 2. Improve student recruitment and retention by supporting students working or doing rotations at the AIDS Institute. 3. Strengthen professional/career development opportunities.

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Kuniholm, Mark Hugo eRA COMMONS USER NAME (credential, e.g., agency login): 5madecali POSITION TITLE: Associate Professor of Epidemiology and Biostatistics EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

Colorado College, Colorado Springs, CO

B.A.

1996

Biology

University of California, Davis, CA

M.S.

2002

Epidemiology

Johns Hopkins University, Baltimore, MD

Ph.D.

2007

Epidemiology

Johns Hopkins University, Baltimore, MD

Postdoc

2007-2008

Epidemiology

INSTITUTION AND LOCATION

FIELD OF STUDY

A. Personal Statement B. Positions and Honors Positions and Employment 1997 - 1999 Peace Corps Volunteer, U.S. Peace Corps, Benin, Africa.

1999 - 2000 Laboratory Technician, Department of Plant Pathology, Cornell University, Ithaca, NY 2000 - 2002 Post-Graduate Researcher, HIV/AIDS Epidemiology Branch, Office of AIDS, California Department of Health Services, Sacramento, CA 2001 - 2002 Research Assistant, Division of Infectious Diseases, University of California, Davis, CA 2003 - 2007 Research Assistant, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 2007 - 2008 Postdoctoral Fellow, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 2008 - 2011 Instructor, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 2011 - 2016 Research Assistant Professor, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 2016 - 2018 Associate Professor, Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York 2018 Associate Professor (with tenure), Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York Ad Hoc Reviewer Clinical Infectious Diseases, Journal of Infectious Diseases, Emerging Infectious Diseases, AIDS, Hepatology, American Journal of Epidemiology, Environmental Health Perspectives, BMC Infectious Diseases, PLOS ONE, International Journal of Infectious Diseases, Journal of Medical Virology, Archives of Virology, Clinical Microbiology Reviews, Intervirology

Teaching Experience 2000 Teaching Assistant. Department of Statistics, University of California Davis 2003 - 2007 Teaching Assistant. Department of Epidemiology, Johns Hopkins University 2007 - 2008 Co-Instructor. Epidemiology I. Department of Epidemiology, Johns Hopkins University 2009 - 2013 Co-Instructor. Principles of Preventive Medicine. Department of Epidemiology and Population Health, Albert Einstein College of Medicine 2016 Co-Instructor, Infectious Diseases Epidemiology, Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York 2017 (Spring) Lead Instructor, AIDS Epidemiology, Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York 2017 (Fall) Lead Instructor, Molecular Epidemiology, Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York 2017 (Fall) Lead Instructor, Principles of Public Health, Department of Epidemiology & Biostatistics, School of Public Health, University at Albany, State University of New York Honors 2001 2004 2011 2009 - 2015

Graduate Student Merit Award, University of California, Davis Campaign for Epidemiology Scholarship, Johns Hopkins University Outstanding Poster, EMBO Conference on Host Genetic Control of Infectious Diseases Clinical Research Loan Repayment Program (LRP) Award, NIAID/NIH

C. Contributions to Science 1. Human Leukocyte Antigen (HLA) Studies in a Multiracial HIV and HCV Cohort of Women. I published a series of manuscripts outlining HLA associations with different clinically important phenotypes of HCV and HIV infection and imputation of HLA data based on genome-wide association study (GWAS) data. The most influential of these papers has been cited 96 times. a. Kuniholm MH, Kovacs A, Gao X, Xue X, Marti D, Thio CL, Peters MG, Terrault NA, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Harris TG, Young MA, Strickler HD, Carrington M. Specific HLA Class I and II Alleles Associated with Hepatitis C Virus Viremia. Hepatology.

2010; 51(5):1514-22. PMID: 20169624. PMCID: PMC2946382 b. Kuniholm MH, Gao X, Xue X, Kovacs A, Marti D, Thio CL, Peters MG, Greenblatt RM, Goedert JJ, Cohen MH, Minkoff H, Gange SJ, Anastos K, Fazzari M, Young MA, Strickler HD, Carrington M. The Relation of HLA Genotype with Hepatitis C Viral Load and Markers of Liver Fibrosis in HIV-Infected and HIVUninfected Women. Journal of Infectious Diseases. 2011. 203(12):1807-14. PMID: 21606539. PMCID: PMC3100515 c. Kuniholm MH, Anastos K, Kovacs A, Gao X, Marti D, Sette A, Greenblatt RM, Peters M, Cohen MH, Minkoff H, Gange SJ, Thio CL, Young MA, Xue X, Carrington M, Strickler HD. Relation of HLA Class I and II Supertypes with Spontaneous Clearance of Hepatitis C Virus. Genes and Immunity. 2013. 14(5):330-5.

PMID: 23636221. PMCID: PMC3723800 d. Kuniholm MH, Xie X, Anastos K, Xue X, Reimers L, French AL, Gange SJ, Kassaye SG, Kovacs A, Wang T, Aouizerat BE, Strickler HD. HLA Class I and II Imputation in a Multiracial Population.

International Journal of Immunogenetics. 2016. 43(6):369-375. PMID: 27774761 2. Viral Hepatitis and Liver Disease in US Hispanics. My work with the NHLBI-funded Hispanic Community Health Study/Study of Latinos (HCHS/SOL) has led to a better understanding of viral hepatitis and nonalcoholic fatty liver disease (NAFLD) in US Hispanics. a. Kuniholm MH, Jung M, Everhart JE, Cotler S, Heiss G, McQuillan G, Kim RS, Strickler HD, Thyagarajan B, Youngblood M, Kaplan RC, Ho GYF. Prevalence of Hepatitis C Virus Infection in US Hispanic/Latino Adults: Results from the NHANES 2007–2010 and HCHS/SOL Studies. Journal of Infectious Diseases.

2014. 209(10):1585-90. [PMID: 24423693; PMCID: PMC3997577] b. Kallwitz ER, Daviglus ML, Allison MA, Emory KT, Zhao L, Kuniholm MH, Chen J, Gouskova N, Pirzada A, Talavera GA, Youngblood ME, Cotler SJ. Prevalence of suspected nonalcoholic fatty liver disease in

Hispanic/Latino individuals differs by heritage. Clin Gastroenterol Hepatol. 2015. 13(3): 569-76. [PMID: 25218670; PMCID: PMC4333050] c. Jung M, Kuniholm MH, Ho GY, Cotler S, Strickler HD, Thyagarajan B, Youngblood M, Kaplan RC, Del Amo J. The distribution of Hepatitis B virus exposure and infection in a population-based sample of US Hispanic adults. Hepatology. 2016. 63(2):445-52. [PMID: 26523403; PMCID: PMC4718892] d. Kuniholm MH, Jung M, Del Amo J, Talavera GA, Thyagarajan B, Hershow RC, Damas OM, Kaplan RC. Awareness of Hepatitis C Virus Seropositivity and Chronic Infection in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Journal of Immigrant and Minority Health. 2016. 18(6):1257-1265.

PMID: 26864380 3. Hepatitis E Virus Epidemiology. As a postdoc I oversaw the first measurement of HEV seroprevalence in the National Health and Nutrition Examination Survey (NHANES) series of studies. Our paper describing these results has been cited 268 times and along with our letters and commentaries has served to inform our understanding of HEV epidemiology in the US and other industrialized countries. In 2016 we published a paper related to HEV/HIV co-infection in which we established for the first time that chronic HEV infection occurs in HIV+ US women. a. Kuniholm MH, Nelson KE. Of Organ Meats and Hepatitis E Virus: One Part of a Larger Puzzle is Solved. Journal of Infectious Diseases. 2008; 198(12):1727-28. PMID: 18983247 b. Kuniholm MH, Purcell RH, McQuillan GM, Engle RE, Wasley A, Nelson KE. Epidemiology of Hepatitis E Virus in the United States: Results from NHANES III, 1988-1994. Journal of Infectious Diseases. 2009; 200(1):48-56. PMID: 19473098. PMCID: PMC2762746 c. Kuniholm MH, Labrique AB, Nelson, KE. Should HIV-Infected Patients with Unexplained Chronic Liver Enzyme Elevations Be Tested For Hepatitis E Virus? Clinical Infectious Diseases. 2010; 50(11): 1545-6.

PMID: 20433358 d. Kuniholm MH, Ong E, Hogema BM, Koppelman M, Anastos K, Peters MG, Seaberg EC, Chen Y, Nelson KE, Linnen JM. Acute and Chronic Hepatitis E Virus Infection in HIV-Infected United States Women. Hepatology. 2016. 63(3):712-20. PMID: 26646162 Complete List of Published Work in MyBibliography: https://www.ncbi.nlm.nih.gov/labs/bibliography/mark.kuniholm.1/bibliography/public/ D. Additional Information: Research Support and/or Scholastic Performance Ongoing Research Support U01HL146202 Gustafson & Wilson (mPIs) 4/1/2019-3/31/2026 National Heart, Lung and Blood Institute MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) The major aims of this study are to examine the clinical, behavioral, and epidemiological characteristics of HIV infection and associated comorbidities in women and men as they age.

Role: Co-Investigator 2U01AI096299 Anastos & Nash (mPIs) 07/15/2011-06/30/2021 National Institute of Allergy and Infectious Diseases CENTRAL AFRICA INTERNATIONAL EPIDEMIOLOGIC DATABASE TO EVALUATE AIDS (CA-IeDEA) The CA-IeDEA study is the Central Africa component of the global IeDEA network. CA-IeDEA countries include Cameroon, Rwanda, Burundi, Republic of Congo, Democratic Republic of Congo. Data pipelines capture clinical, pharmacy and outcome data from participating HIV/AIDS clinics in CA-IeDEA countries.

Role: Co-Investigator Completed Research Support (last 3 years)

5U01-AI035004 Kathryn Anastos (PI) NIAID/NIDA/NCI/NIH 08/01/1993-12/31/2018 WOMEN'S INTERAGENCY HIV STUDY (WIHS) V The WIHS cohort is the largest long-term study of HIV-infected and at-risk HIV-uninfected women in the United States. Over 500 publications have used WIHS data and numerous sub-studies use the WIHS clinical and scientific infrastructure to investigate a wide range of topics of public health importance. Dr. Kuniholm contributes to the design, analysis, and interpretation of WIHS studies related to HCV and HIV at the Bronx/Manhattan site.

1R01 AI097096-01A1 Liise-anne Pirofski (PI) NIAID/NIH 04/01/2012-03/31/2017 B CELL SUBSETS AND IMMUNITY TO CRYPTOCOCCOSIS The goal of this application is to use mouse models to identify mechanisms by which (the mouse homolog of) IgM memory B cells might potentiate protection against Cryptococcus and to perform human studies to determine if loss of IgM memory B cells is a risk factor for cryptococcosis. Dr. Kuniholm contributed to the design, analysis, and interpretation of the human studies.

OMB No. 0925-0001 and 0925-0002 (Rev. 8/19 Approved Through 10/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Malloy, Rachel Hart. eRA COMMONS USER NAME (credential, e.g., agency login): rachel.malloy@health.ny.gov POSITION TITLE: Director, Bureau of Sexual Health and Epidemiology, Division of HIV/STD Epidemiology, Evaluation and Partner Services, AIDS Institute, NYS Department of Health EDUCATION/TRAINING INSTITUTION AND LOCATION

DEGREE (if applicable)

Completion Date MM/YYYY

FIELD OF STUDY

University of Rochester

B.A.

2003

Psychology

New York Medical College

M.P.H

2008

State University of New York at Albany

Ph.D.

2012

Epidemiology Infectious Disease Epidemiology

A. Personal Statement I have worked in the field of public health for the past 15 years, with a predominate focus on sexually transmitted infections (STis), HIV, and Hepatitis C virus (HCV). I currently serve as the Director of the Bureau of Sexual Health and Epidemiology, Division of HIV/STD Epidemiology, Evaluation and Partner Services at the New York State Health Department’s AIDS Institute. In this role, I oversee sexual health programming, policy, and surveillance in NYS with direct oversight of HIV and STI partner services data for NYS, all reportable STI surveillance in NYS, the NYS STD/HIV Disease Intervention Services Training Center, sexual health education and programming, and coordination of sexual health related policies. Prior to my current position, I coordinated a pilot Partner Services Delivered Data to Care program in NYS with oversight of the data system modifications, ongoing monitoring and evaluation, and program evaluation. I have also served as an HCV epidemiologist focusing on HCV surveillance, care and treatment models, and outbreak response. My current and former positions have all been involved in the State’s efforts to end AIDS as an epidemic in NYS. I have mentored many students (MPH, MS, Ph.D, and DrPH) during my tenure at the NYS Health Department.

Furthermore, I serve as an Assistant Professor at the University at Albany, School of Public Health, Department of Epidemiology and Biostatistics. Serving as a subject matter expert on HCV/HIV/STI epidemiology, I serve to support course offerings and students with aligned research interests. My experience with co-occurring syndemics (HIV/HCV and STI), data analytics, public health programming, and core surveillance activities make me well suited for my role in this Center.

B. Positions and Honors Positions and Employment (Selected) 2001-2003 Research Assistant, Strong Memorial Hospital, Rochester New York 2006 Epidemiology Intern, Sonoma County Department of Public Health, Santa Rosa, California 2006-2007 Research Intern, Office of the Medical Director, March of Dimes, White Plains, New York 2008-2010 Graduate Research Assistant, University at Albany, Albany, New York, School of Public Health, Department of Epidemiology and Biostatistics 2010-2011 Evaluation Specialist, Division of HIV and Hepatitis Health Care, New York State Department of Health, AIDS Institute, Albany, NY

2012-2014

Program Research Specialist III, Division of HIV and Hepatitis Health Care, New York State Department of Health, AIDS Institute, Albany, NY 2014-2016 Program Coordinator/Senior Program Coordinator, Division of HIV/STD/HCV Prevention, AIDS Institute, New York State Department of Health, Albany, New York 2016- 2019 Director, STI Surveillance and Special Projects Unit, Bureau of Sexual Health and Epidemiology, Division of HIV/STD Epidemiology, Evaluation and Partner Services, New York State Department of Health, AIDS Institute, Albany, NY 2019- present Director, Bureau of Sexual Health and Epidemiology, Division of HIV/STD Epidemiology, Evaluation and Partner Services, New York State Department of Health, AIDS Institute, Albany, NY Honors 2003 2003 2008 2008 2008 2008-2010 2011 2015 2016 2017

Psi Chi Honor Society, University of Rochester, Rochester, New York Golden Key Honor Society, University of Rochester, Rochester, New York Excellence in Academic Achievement, New York Medical College, Valhalla, New York Student Assembly Student Presentation Award, American Public Health Association Excellence in Research Award, New York Medical College, Valhalla, New York Graduate Assistant Award, University at Albany, School of Public Health, Albany, New York Health Policy Scholar, Herman Biggs Society, New York NYSDOH Commissioner’s Recognition Award NYS Hepatitis C Testing Law Implementation and Evaluation Team NYSDOH Commissioner’s Excellence Award. Data to Care Program Team Delta Omega Honor Society, University at Albany, School of Public Health, Albany, New York, 2017

C. Contribution to Science Mathematic modeling and epidemiologic methods to understand disease burden The foundation of my research has been working towards better understanding disease burden either through mathematic modeling, or epidemiologic studies. With respect to the former, data sources to directly assess epidemiologic measures (i.e. prevalence, incidence) are not always available. As such, mathematic modeling is a useful tool to quantify disease burden for purposes of public health planning and practice. As a doctoral student, my dissertation focus was on estimating the burden of HCV in New York State. That work was utilized by the Centers for Disease Control and Prevention to inform national level tools for estimation, and is being replicated in New York State to gain updated estimates. Speaking to the latter, where primary data collection is possible, targeted epidemiologic studies are paramount to understanding disease burden. While additional studies are yet to be published, my research continues to include epidemiologic studies focused on priority populations with respect to HIV, HCV, and STIs. Kiesel, A, Hart-Malloy, R, O’Donnell, T, Currenti, S, Martin, E. Changes in Patterns of Extragenital Diagnoses for Chlamydia and Gonorrhea in New York State Over Time. Under consideration with Sexually Transmitted Infections.

Hart-Malloy, R, Rosenthal, M, Patterson, W, Cukrovany, J, Currenti, S, O’Donnell, T, Gunn, J. Syphilis diagnosis among adult males with a history of male-to-male sexual contact living with diagnosed HIV in New York State (excluding New York City). Revised and resubmitted to PLOS One. Zibell, J, Hart-Malloy, R, Barry, J, Fan, L, Flanigan, C. Risk Factors for HCV Infection Among Young Adults in Rural New York Who Inject Prescription Opioid Analgesics. American Journal of Public Health: November 2014, Vol. 104, No. 11, pp.

2226-2232.

Hart-Malloy, R and DiRienzo, G. A quasi-markov model for transmission and disease elimination: Hepatitis C among people who inject drugs. J Med Stat Inform. 2014; 2:8. http://dx.doi.org/10.7243/2053-7662-2-8

Hart-Malloy, R, Carrascal, A, DiRienzo, AG, Flanigan, C, McClamroch K, Smith, L. “Estimating hepatitis C virus prevalence at the state level: a call to increase and strengthen current surveillance systems” American Journal of Public Health; Aug 2013, Vol. 103 Issue 8, p1402 Hart-Malloy, R*, Flanigan, C, Laufer, F. “Hepatitis C associated costs in New York State” Oral presentation. 2013 Hepatitis C Research Consortium, New York City, NY, September 2013.

Zibell, J*, Hart-Malloy, R*, Barry, J*. “Responding to The Recent Increase in HCV Infections among Young Persons Who Inject Drugs in Upstate New York: CDC’s Action Plan for the Prevention, Care & Treatment of Viral Hepatitis as a Model for Federal, State, & Local Collaboration” Panel presentation. 9th National Harm Reduction Conference, Portland, OR, November 2012.

Hart-Malloy, R*, Flanigan, C, Carrascal, A, DiRienzo, AG, Smith, L, McClamroch K. “Hepatitis C virus associated morbidity and mortality in New York State: The current and future burden” Poster presentation. 140th American Public Health Association Annual Meeting and Exposition, San Francisco, CA, October 2012.

Hart-Malloy, R*, Flanigan, C, Carrascal, A. " Estimating the prevalence of Hepatitis C cases in New York State”. Oral presentation, 139th American Public Health Association Annual Meeting and Exposition, Washington D.C., October 2011.

Evaluation of medical care and treatment With respect to HIV, HCV, and STIs, it is known that treatment is prevention. Ensuring proper care and treatment is a necessary step in ending or controlling such epidemics, and therefore evaluations of existing programs and/or practices are needed. I have focused ongoing research to understanding medical care and treatment through evaluating programs funded to provide focused care, directly surveying physicians, and performing extensive literature reviews on existing clinical protocols and guidance.

Flanigan, C*, Rowe, K, Hart-Malloy, R. “Hepatitis C virus (HCV) treatment outcomes in the primary care setting”. Poster Presentation. 2015 National Summit on HCV and HIV Diagnosis, Prevention and Access to Care, Arlington, VA, June 2015 National Vaccine Advisory Committee. Strategies to Achieve the Healthy People 2020 Annual Influenza Vaccine Coverage Goal for Health-Care Personnel: Recommendations from the National Vaccine Advisory Committee. Public Health Rep 2013 Jan-Feb; 128: 7-25.

Flanigan, C*, Hart-Malloy, R. “Evaluating the Quality of HCV Care and Treatment in Primary Care Settings”. Poster presentation. American Association for the Study of Liver Disease Annual Conference, Washington DC, November, 2013 Carrascal, A, Hart-Malloy, R*, Wilson, G. “HIV and hepatitis c training in family medicine residency: An opportunity for workforce development”. Round table presentation, 141st American Public Health Association Annual Meeting and Exposition, Boston, MA, November 2013.

Carrascal, A, Hart-Malloy, R, Wilson, G*, Mosquera, MR, Sahai, L, Carlino, R, Camhi, S. “Outpatient HIV and Hepatitis C Training: A Survey of Family Practice Residency Programs in New York State”. Poster presentation, 12th Family Medicine Education Consortium, Danvers, MA, October 2011.

Implementing best practices Implementation Science is the study of methods to promote the adoption of evidence-based practices, interventions and policies into routine public health and health care settings. In my roles in the AIDS Institute, I have had the opportunity to be involved in public health programming, as well as the evaluation of those programs. The focus of these evaluations has been to ensure the programming is efficient from a scientific standpoint, and can/should be scalable.

Gunn, J, Collura, R, Wang, Z, Richardson-Moore, A, Hart-Malloy, R, Anderson, B. Methodologies used to identify and respond to HIV space-time clusters in the New York State. Drafted for submission.

Hart-Malloy, R, Shrestha, T, Pezzulo, M. Patterson, W, Gunn, J, Johnson, M, Tesoriero, J. Data to Care opportunities: An evaluation of persons living with HIV reported to be “current to care” without current HIV-related labs. Journal of Acquired Immune Deficiency Syndrome. September 2019, Vol. 82, Supplement 1, S13-S19.

Hart-Malloy, R, Rajulu, D, Johnson, M, Shrestha, T, Spencer, E, Anderson, B, Tesoriero, J. Cross Jurisdictional Data to Care: Lessons learned in New York State and Florida. Journal of Acquired Immune Deficiency Syndrome. September 2019, Vol. 82, Supplement 1, S42-S46.

Hart-Malloy, R, Brown, S, Bogucki, K, Tesoriero, J. Implementing a Data-to-Care Initiative for HIV in New York State: Assessing the value of community health centers identifying persons out of care for health department follow-up. AIDS Care, 2018, 30(3), 391-396. doi:10.1080/09540121.2017.1363851 Tesoriero, J, Johnson, B, Hart-Malloy, R, Cukrovany, J, Moncur, B, Bogucki, K, Anderson, B, Johnson, M. Improving Retention in HIV Care through New York's Expanded Partner Services Data to Care Pilot. Journal of Public Health Management and Practice. May/June 2017, Vol. 23, Issue 3, pp 255-263.

Hart-Malloy, R, Tesoriero, J, Johnson, M. Data to Care: A Critical Tool for Ending AIDS in New York State. AIDS.gov.

October 31, 2016 Shrestha, T*, Johnson, B, Tesoriero, J, Hart-Malloy, R. “Trends in Viral Suppression among Individuals Re-linked to Care through an HIV Surveillance Based Data to Care Program, New York State” Oral Presentation. 2016 Northeast Epidemiology Conference. Saratoga Springs, NY, October 2016.

New York State Department of Health AIDS Institute. Partner Services Data to Care Report, New York State (excluding New York City) 2015. Albany, NY: New York State Department of Health National Vaccine Advisory Committee. Strategies to Achieve the Healthy People 2020 Annual Influenza Vaccine Coverage Goal for Health-Care Personnel: Recommendations from the National Vaccine Advisory Committee. Public Health Rep 2013 Jan-Feb; 128: 7-25.

D1. Research Support (Past 3 Years) 6 NH25PS005175 Malloy (PI) $2,340,000/Year 2019-present CDC STD PCHD cooperative agreement for PS 19-1901 “Strengthening STD Prevention and Control for Health Departments” The purpose of this grant is to prevent and control three major STIs: chlamydia, gonorrhea, and syphilis. This five-year grant has nine priority strategies and activities that include: conducting STI surveillance, responding to STI-related outbreaks, identifying persons with STIs and linking them and their partners to care and to treatment through targeted disease investigation and intervention, promoting CDC-recommended screening, diagnosis, and treatment practices among relevant providers, disseminating local data and information to the health care community and general public, monitoring and developing STI-related policy, developing and strengthening multi- sector partnerships to support STI prevention and control, supporting HIV prevention goals and collaborating with health department HIV programs, analyzing and using data for increased program insights and program improvement.

6 NU65PS004493-05-02 Malloy (PI) $1,062,975/Year CDC PS 14-1408 “STD/HIV Disease Intervention Services Training Center”

2019-present

The purpose of this grant is to increase training capacity in order to strengthen the skills and capacity of Disease Intervention Specialists (DIS) and other partner services provider staff working in or with state/local

health department STD/HIV prevention programs. This grant supports the NYS Prevention Training Center that provides specialized training to new and continuing DIS, and includes and evaluation component.

U62004513 Malloy (PI) $644,683/Year CDC New York State High Impact Care and Prevention Project

2017-2018

The purpose of this project was to improve collaboration among CDC-funded state health departments and HRSA-funded health centers to expand the provision of HIV prevention and care services within communities most impacted by HIV, especially racial/ethnic minorities, and to better serve PLWH. This project sought to develop and implement effective, replicable, and sustainable programmatic models for collaborating with health centers located in high HIV prevalence jurisdictions, to increase health centers’ capacity to deliver HIV prevention and care activities, improve the identification of undiagnosed HIV infection, establish new access points for HIV care and treatment, and improve HIV outcomes along the continuum of care for PLWH.

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES. NAME: Vásquez, Elizabeth eRA COMMONS USER NAME (credential, e.g., agency login): egrubert POSITION TITLE: Associate Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

B.S.

05/1999

Gerontology

Columbia University, Mailman School of Public Health, New York, NY

M.P.H.

05/2002

Epidemiology

New York Medical College, School of Public Health, Valhalla, NY

Dr.P.H.

05/2010

Epidemiology

INSTITUTION AND LOCATION York College, Queens, NY

FIELD OF STUDY

A. Personal Statement I am delighted by the possibility of being part of the ‘Center for Collaborative HIV Research in Practice and Policy (CCHRPP).’ As an Associate Professor in the department of Epidemiology and Biostatistics of the UAlbany School of Public Health, my career focus has been to conduct research that contributes to the public health prevention agenda by evaluating the complex relationship between health behavior, special populations and place. My research themes have been (1) examining physical activity as a component of health and well-being and its relationship to health outcomes; and (2) exploring the role of psychosocial determinants and behavior among racially and ethnically diverse populations. As my research develops, my interests have moved beyond individual-level indicators to those that consider the role of social context and place (e.g. neighborhoods) and their contributions to differential health outcomes within minority subpopulations (Latinos and people aging with HIV). Further, my current research enables me to use epidemiologic and biostatistical methods and theories to examine social factors implicated in the development and distribution of disease and the methods used to investigate these associations. I have strong skills in research design, quantitative research methods, and community-based as well as clinical trial research. My broad interdisciplinary training, a strong foundation in the theory and practice of epidemiology and a nuanced understanding of the social disparities that influence the health process among underrepresented older adults make me well-suited to be the an affiliate investigator for the CCHRPP application. a. Vásquez E, Quiñones AR, Ramires S, Udo T. Association between adverse childhood events and multimorbidity in a racial and ethnic diverse sample of middle-aged and older adults. Innov.

Aging. 2019;3(2):igz016. PMCID: PMC6599428. b. Baker TA, Vásquez E, Minahan JA. Variability of pain outcomes and physical activity among a diverse sample of older men: Is it more than just race? Gerontology and Geriatric Medicine.

Forthcoming. DOI: 10.1177/2333721419878587.

B. Positions and Honors Positions and Employment 1994-1999 Allen Health Care Services, Personnel Recruiter.

1999-2001 New York Foundation for Senior Citizens, Enriched Housing Program Director.

2001-2002 Columbia University, Social Medical Science Department, Graduate Research Assistant 2007-2010 SUNY, Old Westbury, Department of Biological Sciences, Adjunct 2008-2010 New York Medical College, Department of Epidemiology and Biostatistics, Lecturer 2002-2010 Helen Hayes Hospital, Clinical Research Center, Research Scientist (HRI).

2011-2018 SUNY University at Albany, School of Public Health, Assistant Professor 2018SUNY University at Albany, School of Public Health, Associate Professor Honors 2002 2014 2015 2016

Betty Jane Cleckley, Minority Issues Research Award, American Public Health Association Golden Apple, School of Public Health Student, Teaching Award National Institute of Aging Butler-Williams Scholar (former NIA Summer Institute) Delta Omega Honorary Society in Public Health; Faculty inductee, Alpha Gamma Chapter

C. Contributions to Science 1. Evaluation of the effect of specific social and health behaviors on health outcomes among racial and ethnically diverse older adults. As an independent researcher my research focus has been motivated largely by my desire to evaluate health behaviors on health outcomes among racial and ethnically diverse older adults. Sedentary time among older adults is a complex social behavior that has the potential to affect multiple realms of public health practice. Furthermore, in addition to demographic and economic variations the changing racial and ethnic composition of cohorts over 60 years is a potential contributor to the changing physical activity profile of the nation. The studies below reflect my contribution to this line of work: a. Vรกsquez E, Isasi CR, Echeverria SE, Sotres-Alvarez D, Kaplan R, Lamar M, Gellman MD, Palta P, Qi Q, Gonzalez H. Is there a relationship between objectively measured physical activity and sedentary time and cognitive function in U.S. Hispanic/Latino adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Prev Med. 2017;103:43-48. b. Vรกsquez E, Strizich G, Gallo L, Marshall SJ, Merchant GC, Murillo R, Penedo FJ, Salazar C, SotresAlvarez D, Shaw BA, Isasi CR. The role of stress in understanding differences in sedentary behavior in Hispanic/Latino Adults: results from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Journal of Physical Activity and Health. 2016;13:310-7. PMCID: PMC4985239. c. Vรกsquez E, Botoseneanu A, Bennett JM, Shaw BA. Racial/Ethnic Differences in Trajectories of Cognitive Function in Older Adults: Role of Education, Smoking, and Physical Activity. J Aging Health. 2016;28(8):1382-1402. d. Vรกsquez, E., Shaw, B., Gensburg, L., Okorodudu D, Corsino, L. Race and ethnic differences in physical activity and bone density: National Health and Nutrition Examination Survey, 2007-2008.

Prev Chronic Dis. 2013;10:E216. PMCID: PMC3873216.

2. Racial and ethnic differences among risk factors associated with the progression of disability.

Most studies evaluating functional limitations (limitations in activities of daily living and instrumental activities of daily living) in the past three decades have found a decrease in the prevalence of disability among the older adult population. Yet, there is a scarcity of investigations examining the confluence of physical activity

and functional limitations status among racial and ethnic cohorts in later life. As the population of non-Latino Blacks and Latinos ages, attempts to understand the risk factors associated with functional limitations and the progression of disability becomes increasingly complex. Some of my current research focuses on expanding the knowledge of physical activity and function research among older adults and how unconventional risk factors might plausibly impact the functional status of underrepresented individuals. The following studies highlight my contribution to this line of work: a. Vásquez, E., Batsis, J., Germain, C., Shaw, B. Impact of Obesity and Physical Activity on Functional Outcomes in the Elderly: Data from NHANES 2005-2010. J Aging Health. 2014;26(6):1032-46.

PMCID: PMC4429890. b. Batsis JA, CM Germain, E.Vásquez, AJ Zbehlik, SJ Bartels. Physical Activity Predicts Higher Physical Function in Older Adults: The Osteoarthritis Initiative. J Phys Act Health. 2016;13(1):6-16.

PMCID: PMC4596795.

c. Vásquez E, Murillo R, Echeverria SE. Neighborhood social cohesion and walking limitations in ethnically diverse older Latinos in the United States. Ethn Dis. 2019;29(2):247-252. PMCID: PMC64778048. d. Vásquez E, Udo T, Corsino L, Shaw BA. Racial and ethnic disparities in the association between adverse childhood experience, perceived discrimination and body mass index in a national sample of U.S. older adults. J Nutr Gerontol Geriatr. 2019;38(1):6-17.

3. Diabetes and arthritis. Diabetes and arthritis are chronic conditions that negatively affect the individual quality of life, contributing to declines in functioning and in some instances, the inability to independently remain in the community. My research interest was based on the influence of individual health behaviors such as coping mechanism and perceived risk in older adults and these two outcomes. These are some references that reflected my contribution to this line of work: a. Murillo R, Katic B, Gonzalez T, Vásquez E, Echeverria S. The association of diabetes and prediabetes risk perception with leisure-time physical activity and weight loss. Am J Health Promot.

2019;33(4):534-40. b. Hasting J, Vásquez E. Diabetes and tooth loss among working age African Americans: A national perspective. Soc Work Public Health. 2017;32(7):443-451. PMCID: PMC5881378. c. Applyrs, LD, Williams, E, Faith, T, Kamen, D, Vásquez E, Jurkowski, J. Cultural and quality of life considerations when administering corticosteroids as a therapeutic strategy for African American women living with systemic lupus erythematosus. Patient Prefer Adherence. 2018;12:1007-14.

PMCID: PMC6003291. d. Abraído-Lanza, A. F., Vásquez, E., Echeverría, S.E. En las manos de Dios [in God's hands]: Religious and other forms of coping among Latinos with arthritis. J Consult Clin Psychol.

2004;72(1):91-102. PMCID: PMC3657202.

Complete List of Published Work in MyBibliography: https://www.ncbi.nlm.nih.gov/myncbi/elizabeth.vasquez.1/bibliography/public/ D. Additional Information: Research Support and/or Scholastic Performance Ongoing Research Support U01 HL146202, NIH/NHLBI

Gustafson / Wilson (MPIs)

04/01/19-03/31/26

MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (MWCCS Bklyn CRS) The major aims of this study are to examine the clinical, behavioral, and epidemiological characteristics of HIV infection and associated comorbidities in women and men as they age. Research foci in the Bklyn CRS are cardiovascular, pulmonary, cognitive and brain imaging outcomes. Sex differences will also be addressed.

Role: Co-Investigator

R03 AG059113, NIH/NIA Vásquez (PI) 06/15/18-05/01/20 Disability, Nativity and Social Networks among Two Cohorts This study will examine patterns of disability by nativity status and social networks over time using a specific dataset representing a large sample of the elderly population of Mexican descent. The results can be used to design more effective public health policy and intervention approaches that recognize the important role of nativity status and the social network factors for a large segment of the Hispanic population facing significant disability burdens.

Role: PI 1S21MD010692-01 NIH/NIMHD Schell (PI) 01/01/16-12/31/21 The Endowment for Community-Based Health Disparities Research and Training This award aims to increase the university’s research capacity in health disparities. The main goal is to allow the university to recruit more graduate students from underrepresented backgrounds and provide transdisciplinary training in health disparities; recruit more faculty in health disparities from diverse backgrounds, train existing faculty in health disparities and develop new curricula in health disparities.

Role: Co-Investigator and Mentor Completed Research Support New York State Department of Health Tenniswood M / Vásquez E (Co-PIs) 01/01/16-12/31/16 Epidemiological and Diagnostic Approaches to Improving Prostate Cancer Health Outcomes in New York State Role: Co-PI

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Young, Yuchi eRA COMMONS USER NAME (credential, e.g., agency login): YYOUNG2 POSITION TITLE: Associate Professor, Health Policy Management & Behavior, School of Public

Health, University at Albany, State University of New York EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

Johns Hopkins Bloomberg School of Public Health

MPH

07/88-05/89

Johns Hopkins Bloomberg School of Public Health

DrPH

09/89-05/94

Postdoctoral

06/94-08/96

INSTITUTION AND LOCATION

University of Maryland, School of Medicine

FIELD OF STUDY

Public Health Public Health/ Gerontology Gerontology and Long Term Care

A. Personal Statement As a Gerontologist and Nursing Home Administrator, I have personally witnessed the fiscal and clinical challenges of providing those aging with HIV/AIDS the appropriate care. My training and experience in long-term care (LTC) delivery, comparative effectiveness research, and functional disability measures, uniquely qualifies me to study the LTC needs of older adults with HIV/AIDS. In response to the call to end the HIV epidemic by 2030, I plan to 1) conduct a survey to better understand the prevalence of issues related to poverty, lack of family support, discrimination, stigma and level of functional disability and LTC needs; 2) develop a disability instrument to measure functional disability and demands related to LTC; 3) conduct a pilot study related to the newly developed disability instrument; 4) design intervention to slow down the progress of the functional disability, and 5) determine services/accommodations, needs and training for healthcare professionals, and costs associated with the care.

As PI or Investigator on several ongoing and previous grants from NIH, NYSDOH, SUNY Downstate Medical, and Rockefeller College, I have laid the groundwork in the following areas that would constitute my contribution to science by studying whether (see Part C): (1) self-reported preclinical disability in community-dwelling older women is associated with decrements in objective physical performance; (2) concurrent validity of administering the Functional Independence Measure (FIM) by FIM-certified interviewers and a multidisciplinary team can be quantified using hip fracture patients; and (3) home health services intervention delays nursing home admission among community-dwelling older adults with dementia at various levels of disability.

I am new to the field of HIV/AIDS. Based on my research in the field of chronic conditions among older adults (hip fracture and dementia), I would like to expand my scope to include the aging population with HIV/AIDS. I have taken the lead in submitting a NIH grant entitled “Developing a Disability Construct to Measure Long-Term Care Needs of Older Adults with HV/AIDS� (not funded). In preparing this grant, I collaborated with the following researchers who have specific training in HIV/AIDS medicine, health policy research: Drs. Jack DeHovitz (infectious disease & internal medicine), Mark Brennan-Ing (HIV/AIDS gerontological researcher on psychosocial issues and evaluation research), Stephen Karpiak (behavioral research and evaluation), Gus Birkhead (infectious disease, epidemiology), Margaret DiVita (scale development and validation study), Franklin Laufer (health policy and reimbursement, NYSDOH AIDS Institute).

To complement their expertise, I conducted a systematic literature review of more than 40 papers pertaining to functional disability measures and long-term care related to older adults with HIV/AIDS. I also attended the HIV/AIDS scientific meetings/presentations and HIV/AIDS Focus Group discussion during the Gerontological Society of America annual conference since 2015.

I am looking forward to exploring new horizons. I believe that my research interest would complement the mission of the CCHRPP, specifically in the area of academic collaboration and field application to address the public health and social justice challenges in older adults living with HIV/AIDS. My research in aging and long-term care allows me to contribute to future research related to health care provider training and healthcare system preparedness (i.e., home care, nursing home, etc.) with the goal of meeting the needs of HIV/AIDS, gay and transgender people who are challenged by stigma and social injustice.

B. Positions and Honors Position and Employment 2011-present Associate Professor, Department of Health Policy, Management, and Behavior, School of Public Health, State University of New York at Albany 2004-2011

Assistant Professor, Department of Health Policy, Management, and Behavior, School of Public Health, State University of New York at Albany

2001-2004

Assistant Research Professor, The Health Services Research and Development Center, Johns Hopkins Bloomberg School of Public Health

1998-2001

Assistant Scientist, Health Services Research and Development Center, Johns Hopkins Bloomberg School of Public Health, Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, School of Medicine

1996-1998

Research Associate, Health Services Research and Development Center, Johns Hopkins Bloomberg School of Public Health

1994-1996

Post-Doctoral Research Fellow, Division of Gerontology, Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland

Other Experience and Professional Membership Associate member of Center for Social & Demographic Analysis (CSDA, UAlbany) 2008 - present Member of American Public Health Association Member of the Gerontological Society of America Member of American Geriatrics Society C. Contributions to Science C1. Functional Disability and Preclinical Disability My research portfolio comprises evaluations of the clinical, societal burdens of care and financing impacted by a loss of functional independence among the elderly. To this end, I have acquired broad experience in the application of disablement pathways for the following conditions: preclinical disability, frailty, hip fracture, surgical repair, postacute rehabilitation, post-acute functional recovery, and functional disability (due to incomplete recovery). These evaluations have advanced my discipline (gerontology) by providing clinicians with the means to quantify the spectrum of health care services needed to foster functional independence. To accomplish these research studies, I validated the administration of the Functional Independence Measures (FIM™ instrument) for hip fracture patients through interviews instead of the typical multidisciplinary team approach (i.e., physician, nurse, physical therapist, social worker). This experience with respect to the FIM is critical to my future research to customize the FIM to the HIV/AIDS population. As with my hip fracture study, I contacted Dr. Carl Granger (FIM founder) and his research group for consultation. They are supportive of my endeavor.

a. Yuchi Young, Maksim Papenkov, Taeko Nakashima (2018). Who is Responsible? A man with dementia wanders from home, is hit by a train, and dies. Journal of American Medical Directors Association, 2018 jul; 10(7): 563567. b. 2. David Hornick, Christopher Paynter, Michael W. Dailey, Yuchi Young (2016). End-of-life care: Whose decision is it anyway? J of Palliative Medicine, 19(9): 904-904. doi:10.1089/jpm.2016.0159. c. Roy Mathew, Wan-Hsiang Hsu, Yuchi Young, (2013). Effect of Comorbidity on Functional Recovery a after Hip Fracture in the Elderly. Am. J. Phys. Med. Rehabil. 92(8): 686-696. d. Yuchi Young, Kuangnan Xiong, Robert M. Pruzek, (2010). Functional Recovery After Post-Acute Rehabilitation in Older Hip Fracture Patients: The Role of Cognitive Impairment and Implications for Long-Term Care. J Am Med Dir Assoc, (doi:10.1016/j.jamda.2010.08.005) C.2. Reduce Avoidable Hospitalization among Nursing Home Residents Medical science and technology advancements have increased life expectancy and survival among people with disabilities, while aging-in-place initiatives have delayed nursing home admissions. Thus, nursing homes are now admitting residents with increasingly complex chronic diseases and more severe disabling conditions by providing postacute or intensive care. A hospital admission from the nursing home is not only costly; it induces unnecessary emotional stress on patients and families and increases the risk of iatrogenic diseases and other adverse outcomes. As a result, potentially avoidable hospitalizations are an indicator of poor nursing home quality and a target for quality improvement. Few studies have examined the determinants related to preventable hospitalizations in nursing homes.

With a grant from the Commonwealth Foundation and NYS/DOH, for which I was the PI, I conducted a web-based survey of medical directors (MDs) and directors of nursing (DONs) from 300 randomly selected nursing homes in New York State to determine risk factors associated with preventable hospitalization.

Efficient and effective care depends on continuity of communication between nurses and physicians and adequate access via electronic health records (EHRs) to patients’ medical history/labs/EKGs. Next, we examined the varying views between MDs and DONs regarding determinants of transfers. We hypothesized that MDs and DONs within the same nursing home would have similar views regarding factors associated with preventable hospitalization. We found that the four significant determinants identified by MDs as influential in preventable hospitalization were not endorsed by DONs (i.e., access of MD and nurse practitioner by pager, family preferences, access to medical records, and better paid physicians). This discrepancy in perceptions between MDs and DONs may complicate interventions to improve care and reduce preventable hospitalization.

We concluded that two intervention strategies may reduce preventable hospitalizations: 1) increase use of EHRs to access lab results and other health records, and 2) provide training to staff to improve communication between nursing, MDs and DONs. Our study results were well received by the NYS DOH and were recommended for facility specific policies and procedures guidelines. The experience of questionnaire development, data collection and collaboration with MDs, DONs and nursing home administrators will give me insights regarding primary data collection and collaboration with Downstate Medical Center. a. Taeko Nakashima, Yuchi Young, Wan-Hsiang Hsu (2019). Do Nursing Home Residents with Dementia Receive Pain Assessments and Interventions? Journal of Alzheimer’s Disease & Other Dementias. 2019 May; 34(3):193198. b. Yuchi Young, John Kalamaras, Lindsay Kelly, David Hornick, Recai Yucel (2015). Is Aging in Place Delaying Nursing Home Admission? Journal of the American Medical Directors Association. October 2015;16(10): 900.e1-900.e6. c. Yuchi Young, Nancy R. Barhydt, Suzanne Broderick, Anna D. Colello, Edward L. Hannan (2010). Factors Associated with Preventable Hospitalization among Nursing Home Residents in New York State: A Survey of Directors of Nursing. Journal of American Geriatrics Society, 58(5), 901-907.

d. Yuchi Young, Sumant Inamdar, Beth S. Dichter, Harold Kilburn Jr., Edward L. Hannan (2010). Clinical and NonClinical Factors Associated with Potentially Preventable Hospitalization Among Nursing Home Residents in New York State. J Am Med Dir Assoc. 11(2): 364-371 e. Yuchi Young, Sumant Inamdar, Nancy R. Barhydt, Anna D. Colello, Edward L. Hannan (2010). Preventable Hospitalization Among Nursing Home Residents: Varying views between Medical Directors and Directors of Nursing Regarding Determinants. Journal of Aging and Health, 22, 169-182.

C.3. Does Coordinated Care Reduce Health Care Utilization and Improve Functional Independence?

Care coordination emerged as a central theme in my hip fracture studies. Functional recovery along the continuum of long-term care—acute care, surgical repair, post-acute rehab, home rehab, and home care—requires effective care coordination. Using a seed grant from the University at Albany, for which I was the PI, I conducted a survey in two retirement communities in Ithaca, NY to compare the effectiveness of coordinated care between residents of retirement communities who received coordinated care and general community-dwelling older adults who did not (using the national representative Longitudinal Study on Aging (LSOA-II data) on physical function, health service utilization, and perceived quality of life.

We found that compared to those without coordinated care, residents with access to on-site comprehensive services had substantially less risk for activities of daily living (ADL) limitations and Nagi functional impairments. The residents also had better self-reported health than the comparison group. The positive association of on-site comprehensive access is multidimensional, enhancing not only functional outcomes but, also, overall self-rated health. Risk factors associated with permanent transition to nursing homes (11% of residents) were depression, incontinence, dementia and functional disability. These results provided the Continuing Care Retirement Community (CCRC) the requisite information to plan for and deliver appropriate health services to their residents. Our research findings validated that coordinated care is an efficient way to deliver LTC services. A similarly coordinated care approach can be applied to the HIV/AIDs population in designing LTC services. a. Taeko Nakashima, Yuchi Young, Wan-Hsiang Hsu (2017). Are hospital/ER transfers less likely among NH residents with Do Not Hospitalize orders? Journal of American Medical Directors Association. 18(5):438-441. b. Yuchi Young, Sumant Inamdar, Ed Hannan. (2010). Comparison Study on Functional Outcomes and Perceived Quality of Life Between All-Inclusive and Fee-For-Service Continuing Care Retirement Communities. J Am Med Dir Assoc, 11(4), 257-262. c. Yuchi Young, Yen-Hong Kuo. (2010). Comparison Study on the Physiological and Functional Change and Health Care Utilization Overtime Between Disabled Older Women With and Without Hip Fracture., J Am Med Dir Assoc 11(2), 100-105. d. Yuchi Young. (2009). Factors Associated with Permanent Transition from Independent Living to Nursing Home in a Continuing Care Retirement Community. J Am Med Dir Assoc.10 (7), 491-497.

D. Research Support and/or Scholastic Performance Ongoing Research Title of Grant: Health Administration Certificate Training Program – Ukraine Healthcare Reform Sponsoring Agency: USAID Date: 07/01/2019-08/31/2020 Funding level: $87,145 Principal Investigator: Jack DeHovitz Investigator: Yuchi Young Main Objectives: To support the healthcare reform in Ukraine, this grant aims to strengthen the health workforce

to support a transparent, accountable, and effective health care system that is capable of meeting the health needs of the Ukrainian people (USAID Health Reform Support Objective 3). This subcontract will support healthcare professional training for health administrators and managers at the regional and national levels.

Title of Grant: A comparative policy analysis of programs to support people with dementia and co-existing complex needs and their caregivers Sponsoring Agency: Canadian Institutes of Health Research Date: 01/01/2019-12/31/2022 Funding level: $505,284 ($29,000 matching fund came from University of Toronto) Principal Investigator: Gregory Marchildon Principal Investigator for New York State: Yuchi Young Main Objectives: to compare programs to support people with dementia and complex needs, and their unpaid caregivers in 5 jurisdictions: Newfoundland & Labrador, Ontario, British Columbia, Vermont, and New York State. We will draw on a collaboration between researchers and policymakers, called a "North American Observatory of Health Systems and Policies" to support the improvement of health care systems across North America.

Title of Grant: Successful Aging Study Sponsoring Agency: The University at Albany Foundation Date: 01/01/2018-12/31/2019 Principal Investigator: Yuchi Young Funding level: $30,000 Main Objectives: Building on the PI’s prior work, the Successful Aging study intends to 1) operationalize successful definition, 2) quantify successful aging using a multidimensional construct that integrates physiological, psychological and sociological domains, and 3) validated the domain structure and content validity with primary data collection.

Grants not funded Title of Grant: Developing a Disability Construct to Measure Long-Term Care Needs of Older Adults with HV/AIDS (submitted on 1/7/17) Funding level: $275,000 Dates: 08/15/17-8/14/19 Sponsoring Agency: NIH (R21) Co-Principal Investigators: Yuchi Young (SPH) and Kamiar Alaei (RC-GIHHR) Main Objective: to develop a functional disability Construct to measure long-term care needs of older People with HIV/AIDS. Selected Completed Research Support Title of Grant: New York State Federal-State Health Reform Partnership Medicaid Section 1115 Demonstration Evaluation Dates: 01/13/14-05/15/15 Sponsoring Agency: NYS Department of Health Principal Investigators: Erika G. Martin and Don Boyd Co-Investigator: Yuchi Young (Lead Investigator in long-term care component) Main Objective: to evaluate the New York State Federal-State Health Reform Partnership Medicaid Section 1115 Demonstration project (Young: focus on long-term care restructuring and expansion of managed long term care.)

Title of Grant: Evaluation of Gold STAMP Intervention on Pressure Ulcer Reduction Sponsoring Agency: Medicaid Redesign Team (MRT), NYSDOH Date: 04/01/2011-03/31/2013 Principal Investigator: Yuchi Young Main Objectives: To evaluate the effectiveness of the Gold STAMP intervention program which aims to reduce pressure ulcers in New York State. This goals of this evaluation are to: (1) describe the intervention process, and (2) evaluate the most effective modalities in reducing pressure ulcer incidence and prevalence rates and associated costs.

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Fox, Ashley M. eRA COMMONS USER NAME (credential, e.g., agency login): ASHLEYFOX POSITION TITLE: Assistant Professor, Public Administration and Policy, University at Albany, State

University of New York EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

University of Connecticut

B.A.

2001

Political Science

University of Connecticut

M.A.

2002

Columbia University

Ph.D.

2009

Political Science Sociomedical Sciences Global Health and Population

INSTITUTION AND LOCATION

Harvard University Yale University

Postdoctor al Fellow Postdoctor al Fellow

2010 2011

FIELD OF STUDY

Health Policy

A. Personal Statement Ashley M Fox, PhD, MA will serve as a collaborator on the grant. Dr. Fox is trained as a social demographer and health policy researcher. She has written extensively on HIV/AIDS policy issues in low -and middle-income countries.

B. 2002-2004

Positions and Honors Research Associate, Yale University, Center for Interdisciplinary Research on AIDS

2009-2010

Postdoctoral Fellow, Department of Global Health and Population, Harvard University

2010-2011

Agency for Health Care Research and Quality Fellow, Yale University

2011-2014

Assistant Professor, Icahn School of Medicine at Mount Sinai, Department of Health Evidence and Policy, New York, NY

2014-

Assistant Professor, University at Albany, State University of New York, Department of Public Administration and Policy, Albany, NY

C. Contributions to Science One strand of my research focusses on explaining global variations in HIV infection rates. Specifically, I have examined the contribution of socio-economic factors, multiple sexual partners and male circumcision in explaining variations in HIV prevalence within and between countries.

1. Fox, A.M. (2014). “Marital concurrency and HIV risk across 16 African countries,” AIDS and Behavior, 18(4):791–800.

2. Fox, A.M. (2012). “The HIV-poverty thesis re-examined: poverty, wealth, or inequality as a social determinant of HIV infection in sub-Saharan Africa?” Journal of Biosocial Science, 44, 459–480.

3. Fox, A.M. (2010). “The social determinants of HIV infection in sub-Saharan Africa: An inverse relationship between poverty and HIV?” Public Health Reports, 125(S4): 16-24.

A second stream of research focusses on gender and HIV and on explaining why women have almost two-fold risk of HIV in most African countries. Part of this research examines the relationship between violence against women and HIV and the degree to which this relationship is causal as well as the mechanisms explaining this relationship.

4. Adams, J.L., Hansen, N.B., Fox, A.M., Taylor, B.B., Van Rensburg, M.J., Mohlahlane, R., Crewe, M., Sikkema, K.J. (2011). “Correlates of HIV testing among abused women in South Africa,” Violence Against Women, 17: 1014-1023.

5. Sikkema, K.J., Neufeld, S.A., Hansen, N.B., Mohlahlane, R., Van Rensburg, M.J., Watt, M.H., Fox, A.M., Crewe, M. (2010). "Integrating HIV prevention into services for abused women in South Africa," AIDS and Behavior, 14: 431–439.

6. Fox, A.M. (2007). “Gender transformation requires population approaches to addressing gender-based violence and HIV,” Sexually Transmitted Infections, 83(6): 499.

7. Fox, A.M., Jackson, S., Hansen, N., Gasa, N., Crewe, M., Sikkema, K. (2007). “In their own voices: A qualitative study of violence against women and HIV in South Africa,” Violence Against Women, 13(6): 583602.

8. Akunkunda D., Fox, A.M., Lynch, C. “Couple-level Age and Educational Asymmetries and HIV Risk in Kenya,” BMC Women’s Health (R&R).

A third stream of my research focusses on measuring and explaining variations in government’s policy responses to HIV. Several articles have established best practices for measuring government commitment to respond to HIV. Other research in this domain explains variations in HIV policy responses based on public preferences and identity politics within countries.

9. Fox, A.M. (2014). “AIDS policy responsiveness in Africa: Evidence from opinion surveys,” Global Public Health, 9(1–2): 224–248: http://www.tandfonline.com/doi/full/10.1080/17441692.2013.879483.

10. Gore, R., Fox, A.M., Goldberg, A., Baernighausen, T. (2014). “Bringing the state back in: understanding and validating measures of governments’ political commitment to HIV,” Global Public Health, 9(1–2): 98– 120.

11. Goldberg A., Fox A.M., Gore R., Baernighausen T. (2012). “Indicators of political commitment to respond to HIV,” Sexually Transmitted Infections; 88:e1. doi:10.1136/sextrans-2011-050221.

12. Fox, A.M., Goldberg, A., Gore, R., Baernighausen, T. (2011). “Conceptual and methodological challenges to measuring political commitment to respond to HIV,” Journal of the International AIDS Society, 14(Suppl 2):S5-S18.

D. Additional Information: Research Support and/or Scholastic Performance COMPLETED 30938 (Fox) 11/2014-04/2016 Robert Wood Johnson Foundation, Public Health Law Variations in state welfare generosity and preterm birth in the US: Can it explain our low international infant mortality rankings?

This study aims to explain the wide variation in state preterm birth rates and the US’s poor international rankings on infant mortality with reference to variations in state welfare generosity (the various laws establishing eligibility, enrollment and value of benefits for welfare programs). Specifically, the study will examine the contribution of variations in the generosity of five major welfare programs on state preterm birth outcomes: unemployment insurance, income support (AFDC/TANF), food assistance (SNAP & WIC) and Medicaid.

Amount: $150,000 Role: PI 1U24MD006961-01 (Boden-Albala) 09/22/11–12/31/13 NINDS/NIMHD Northern Manhattan Initiative for Minority Involvement in Clinical Trials This study uses novel innovative methodology to identify and provide strategies for optimal enrollment of minority populations in neurological trials and studies. This includes the completion of a global recruitment toolkit for neurological researchers.

Role: Co-Investigator R24 MD001691 (Horowitz) NIMHD 07/01/08-01/31/13 Title: Help Educate to Eliminate Diabetes (HEED) This study is a weight loss intervention trial for overweight and obese prediabetic adults and adults with normal sugars.

Role: Investigator CDC 5U58DP001010 (Horowitz) CDC 09/30/07-08/31/13 Centers for Disease Control and Prevention's REACH US Initiative Title: Communities IMPACT Diabetes Funding to develop sustainable, community-based diabetes prevention programming in East Harlem, NY. Role: Investigator 5P60 MD000270 (Bickell) 9/11/07- 4/30/13 NCMHD Center for Achieving and Sustaining Improved Health in Harlem Overcoming Barriers to Effective Care for Minorities The main goal of this center grant is to integrate a coordinated series of research activities using selfmanagement skills for patients with vital community outreach and training efforts which will enhance the minority health services research infrastructure in our community.

Role: Investigator

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Deborah Ruth Gustafson eRA COMMONS USER NAME (credential, e.g., agency login): DGUSTAFSON POSITION TITLE: Professor EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

University of Minnesota, Twin Cities, MN

BS

06/1989

Biology

University of Minnesota, Twin Cities, MN

MS

06/1991

Nutrition Science

University of Minnesota, Twin Cities, MN

PhD NCI/NIH Post-doc

08/1995

Nutritional Epidemiology

07/1996

Genetic Epidemiology

INSTITUTION AND LOCATION

University of Minnesota, Twin Cities, MN

FIELD OF STUDY

A. Personal Statement I am a translational aging and neuroepidemiologist with >25 years of experience in multidisciplinary research studies focused on the intersection of aging, infectious and chronic diseases, and co-morbidities, with an emphasis on adiposity and vascular exposures and neuropsychiatric outcomes including cognition, cognitive impairments, Alzheimer’s Disease and Related Disorders (ADRD), including vascular cognitive disorders. I am mPI of the MACS/WIHS Combined Cohort Study (MWCCS) Brooklyn Clinical Research Site (BKlyn CRS), co-Chair the MWCCS Aging Working Group, oversee the MWCCS women’s frailty protocol, and contribute to the MWCCS Neuropsychology Working Group. Given my interest in cardiovascular measures, adiposity, cognition and brain aging, I am or have been a MWCCS Bklyn CRS site PI for NHLBI-funded substudies of sleep, ECG, Echo, and pulmonary function. I have also been successful in being awarded unobligated funding through NIAID for several Brooklyn-only substudies exploring peripheral adiposity biomarkers including adipokines, lipidomics, and gut hormones, as well as neuronal biomarkers (e.g., nerve growth factor, ApoCIII, ApoE and S100B; and aging biomarkers (e.g., miRNAs) to associate with aging outcomes obesity, bone health, cardiovascular disease, cancers and frailty.

In 2018, I have an approved MWCCS Concept for secondary data analyses on 10 year cardiovascular phenotype trajectories in association with cognition in women. We have explored one aspect of the proposed analyses already in the MWCCS men (Neurology, in press). In addition, as Chair of the Vascular Cognitive Disorders Professional Interest Area (VPIA) for Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART), I proposed this theme for a data analytics workshop for junior investigators held in conjunction with the Alzheimer Association International Congress (AAIC) in July 2018. The partner organization for this workshop was The Integrative Analysis of Longitudinal Studies of Aging and Dementia (IALSA) research network (NIH/NIA P01AG043362, www.maelstrom-research.org). The workshop was entitled, ‘Multivariate associations of vascular risk factors and cognitive functioning’. MWCCS women’s data was included in this workshop. Consultants on this proposal, Drs. Rubin (MWCCS) and Clouston (IALSA) were involved. Also in 2018, I became a mentor for the NIMH-funded Sustained Training in HIV & Aging Research (STAHR, D. Jeste, PI) Program, via the successful application of Dr. Elizabeth Vásquez, co-Investigator on this proposal and my mentee. Via STAHR, we meet annually to discuss mentee research progress and forge collaborations. In addition, I have mentored 45 MS, PhD and/or medical students over the last 21 years, since 1998.

In summary, I have collaborated with a diverse group of investigators to support high impact translational research. As aforementioned, I Chair the VPIA for the Alzheimer Association (act.alz.org/site/SPageServer?pagename=ISTAART_PIA_VCD), am on the Executive and 2018 Program

Committees of the International Society of Vascular Behavioural and Cognitive Disorders (VasCog) (www.mect.cuhk.edu.hk/vascog2018/), and member of the New York City Regional Obesity Forum (NYCROF).

I am an Associate Editor for Alzheimers & Dementia (Alz & Dem), the Journal of Alzheimer’s Disease (JAD) and Advances in Geriatric Medicine and Research. In October 2017, I was invited to participate in an NIA special emphasis panel on ‘Cost Effective Early Detection of Cognitive Impairment’. I was asked to speak on ‘Low-Cost Cognitive Assessment Among Low SES and Diverse Populations’. The meeting summary document is in the public domain at https://www.nia.nih.gov/sites/default/files/2018-01/final-cognitive-declinesummary.pdf. More recently, I am an invited discussant at an NIA/OAR workshop entitled ‘HIV & Neurodegeneration’ (May 1-2, 2019).

In 2014 we were funded by the State of New York Empire Clinical Research Program (ECRIP) for a physician training grant, ‘HIV in Women: Focus on Microvascular Function’, which included peripheral vascular measures, body composition via iDXA, and leptin measures in MWCCS Bklyn CRS women participants. My role as ECRIP Center Director brought a unique perspective to the intersection of infectious and chronic diseases, co-morbidities, and aging and neuroepidemiology.

My background also includes a period as research faculty in Sweden, where I served as a Work Package PI of LipiDiDiet, a major European Union multidisciplinary and translational project, which explored the role of fatty acids in brain structure and function, cognition and dementia (www.lipididiet.eu). As a result, I continue an active collaboration with Dr. Amanda Kiliaan at Radboud University Medical Center in the Netherlands. In 2019, we have analyzed the differential associations of adiposity measures with both cerebrovascular and neurodegenerative brain outcomes in the RUN-DMC Study. I am also mPI of the Tucson Indian Center Heart Mind study where we explore cardiovascular factors in association with cognition and depressive symptoms in Arizona American Indian communities. This follows pilot work in New Mexico. I am PI of the Brooklyn Cognitive Impairments & Health Disparities (BCI-HD) Pilot Study, where we implement the FDA-approved Cognigram (digital cognitive performance assessment) in primary care settings in central Brooklyn.

In addition, I have extensive experience in studies seeking to better understand the unintended side-effects of routinely prescribed medications (e.g., body weight loss in AD); identification of functional gene polymorphisms related to disease risk and metabolism (e.g., APOE, ACE); creation of clinical cohorts for the identification of clinical and pre-clinical biomarkers and staging of disease processes (e.g., Argentina AD Neuroimaging Initiative, ADNI2AR); associating body mass index and waist-to-hip ratio with aging brain structural and functional outcomes (e.g., brain atrophy/volume, white matter lesions/hyperintensities, and the ‘AD signature’) and cerebrospinal fluid biomarkers (e.g., A-40, A-42, Tau). The following 4 publications, in addition to those included in my Contribution to Science, illustrate my approach to investigating the intersection of aging, vascular, and cognitive areas of expertise: 1. Rubin LH, Gustafson D, Hawkins KL, Zhang L, Jacobson LP, Becker JT, Munro CA, Lake JE, Martin E, Levine A, Brown TT, Saktor NC, Erlandson KM. Midlife adiposity predicts cognitive decline in the Multicenter AIDS Cohort Study (MACS). Neurology, in press.

2. Arnoldussen IAC, Gustafson DR (co-first authors), vanLejsen EMC, deLeeuw FE, Kiliaan AJ. Adiposity is related to cerebrovascular and brain volumetry outcomes in the RUN DMC Study. Neurology, in press.

3. Gustafson, DR. Epidemiology informs clinical trials of cognitive impairments and late-onset dementias. J Neurol Neuromedicine, 2018;3:13-18.

4. Gustafson DR, Bäckman K, Joas E, Waern M, Östling S, Guo X, Skoog I. 37 years of body mass index and dementia. Observations from the Prospective Population Study of Women in Gothenburg, Sweden. J Alzheimers Disease 2012;28:162-171.

I have received grants from the National Institutes of Health (NIH), the European Commission, the Swedish Research Council, and the Swedish Brain Power Project. I have over 180 peer-reviewed or invited publications, and am an invited speaker at international meetings on the topics of adiposity, vascular factors, frailty and prevention of dementia and other psychiatric disorders in the elderly. Spanning my research and teaching career, I have engaged in translational, multidisciplinary and interdisciplinary projects, and have experience with basic science approaches (adipose tissue cell culture), clinical studies, and aging, dementia, nutritional, cancer, genetic and molecular epidemiology.

B. Positions and Honors 1996-2002 Assistant Professor, Department of Nutrition and Food Sciences, Utah State University, Logan, UT

2003-2004 2004-2005 2007-2012 2005-2009 2009-2011 2011-2013

20132014-2019 2014 2015-2020

Assistant Professor, Department of Family and Community Medicine, Division of Research, Medical College of Wisconsin, Milwaukee, WI Researcher, Section for Psychiatry and Neurochemistry, University of Gothenburg, Sweden Senior Researcher in Psychiatric Epidemiology, Swedish Research Council, University of Gothenburg, Sweden Associate Professor, Section for Psychiatry and Neurochemistry, University of Gothenburg, Sweden Visiting Associate Professor, Department of Neurology, SUNY-Downstate Medical Center, Brooklyn, NY Visiting Professor, Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (Foundation for the Fight against Neurological Diseases in Childhood, FLENI), Buenos Aires, Argentina Professor, Director of NeuroEpidemiology, Department of Neurology, State University of New York-Downstate Medical Center, Brooklyn, NY Affiliate Researcher, Section for Psychiatry and Neurochemistry, University of Gothenburg, Sweden Visiting Professor, Université de Versailles, Paris, France Guest Professor, Department of Health and Education, University of Skövde, Skövde Sweden

Selected Experience and Professional Memberships 08/2005 Docentur/Associate Professor awarded at University of Gothenburg, Sweden 04/2007 Recipient of a mid-career research fellowship, Senior Researcher in Psychiatric Epidemiology, Swedish Research Council 07/2010 Invited symposium, Vascular and Metabolic Factors in Dementia, International Congress on Alzheimer’s Disease 01/2011 Invited discussant, World Health Organization, International Association for Geriatrics and Gerontology (IAGG), and Société Francaise de Gériatrie et de Gérontologie workshop entitled, ‘Health promotion program on prevention of late onset dementia’, Geneva, Switzerland.

12/2012 Co-organizer/host of a symposium on Overnutrition, Cognition and Aging at the New York Academy of Sciences in New York City 04/2013 Rapporteur, European Commission Innovation for Healthy Ageing, DG SANCO, ‘Frailty in old age, a public health concern at EU level’ 09/2014 Featured researcher, Lancet Neurology, Vol 13.

2014-2017 Member of the organizing committee for 2 workshops on vascular cognitive impairment: translational approaches, the Anne & Albert Charitable Trust, Naples, Florida, USA. 2015 Selected Symposium ‘Frailty in HIV Infection’, International Congress on Frailty and Sarcopenia Research 2015, Boston, USA. 2015-2017 Member, Alzheimer’s Disease and Related Disorders (ADRD) Metabolism and Neurocognitive Disorders Working Group (NIH/NIDDK) 2015 Invited speaker, The International Society of Vascular Behavioural and Cognitive Disorders, ‘Vascular Risk Factors and the Vascular Etiology of AD’. Tokyo, Japan.

2017 Selected participant in the SUNY Downstate Leadership Development Program,, provided by Baruch College and SUNY Downstate Medical Center, New York City 2017 Invited speaker, ‘Frailty and aging in HIV infection’, New York University HIV in Aging Symposium, New York City, USA. 2017 Invited speaker, ‘Turbocharged: HIV and Aging in Women’, Center for AIDS Research HIV and Aging series, Emory University, Atlanta, USA. 2017-2018 Executive and Program Committee Member & invited speaker on Dementia Prevention, The International Society of Vascular Behavioural and Cognitive Disorders (VasCog).

2018 Invited speaker, ‘Adiposity and Dementia’, Dutch Neuroscience Meeting, Lunteren, NL. 2019 Invited speaker, ‘Aging Women with HIV: Enquiring Minds Want to Know’, HIV and Aging: From Mitochondria to the Metropolis, Atlanta, USA.

2017-2019

2019

Vascular Cognitive Disorders Professional Interest Area (VPIA) Chair, Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) Featured Research Session Chair and session organizer: Vascular Contributions to Alzheimer's Disease and Related Disorders: A Diverse Global Perspective; and 3 accepted Abstracts, Alzheimer’s Association International Congress, Los Angeles.

C. Contribution to Science (selected examples of over 180 publications*) 1. Exploring traditional ‘aging’ hypotheses related to physical and cognitive functions in vulnerable populations and communities with a focus on women.

Background: I have explored cognition, vascular, physical and socioeconomic factors in MWCCS women (formerly WIHS), Swedish women, Southwest Tribal elders, the Argentina Alzheimer’s Disease Neuroimaging Initiative (ADNI), and the TRELONG Study in Treviso Italy.

1. Adler K, Apple S, (co-first authors), Cheng F, Friedlander A, Cohen C, Levine S, Lucchesi M, Maruff P, Reinhardt M, Salmieri M, Stevens D, Weingast SZ, Gustafson DR. The Brooklyn Cognitive Impairment & Health Disparities Pilot Study, Alzheimers Dementia, in press.

2. Gustafson DR, Shi, Q, Holman SA, Minkoff H, Cohen M, Plankey MW, Havlik R, Sharma A, Gange S, Gandhi M, Milam J, Hoover D. Predicting death over 8 years in a prospective cohort of HIV-infected women. The Women’s Interagency HIV Study. BMJ Open, 2017; 7:e013993.

3. Gustafson DR, Mielke MM, Tien PC, et al. Anthropometric measures and cognition in middle-aged HIVinfected and uninfected women. The Women's Interagency HIV Study. J Neurovirol 2013; 19(6): 574-85.

4. Gustafson DR, Shi, Q, Thurn M, Holman SA, Minkoff H, Cohen M, Plankey MW, Havlik R, Sharma A, Gange S, Gandhi M, Milam J, Hoover D. Frailty and constellations of associated factors in middle-aged HIV-infected and uninfected women. The Women’s Interagency HIV Study. J Frailty Aging, 2016;5:43-8.

PMCID: PMC4957016.

2. Exploring biomarkers related to aging, cognition and dementias.

Background: Preclinical biomarkers for dementia and AD are lacking. I have investigated brain and peripheral adiposity biomarkers in association with cognition, cognitive decline and dementia, as well as other outcomes such as breast cancer and polycystic ovary syndrome (PCOS).

1. Arnoldussen IAC, Sundh V, Bäckman K, Kern S, Östling S, Blennow K, Zetterberg H, Skoog I, Kiliaan AJ, Gustafson DR. A 10 year follow-up of adiposity and dementia in Swedish adults aged 70-years and older. J Alz Dis, 2018;63(4):1325-1335.

2. McFarlane SI, Mielke MM, Uglialoro A, Keating SM, Holman S, Minkoff H, Crystal H, Gustafson DR. Ghrelin, amylin, gastric inhibitory peptide and cognition in middle-aged HIV-infected and uninfected women. The Women’s Interagency HIV Study. Neurology & Neurophysiology, 2017, Epub.

3. Gustafson DR, Mielke MM, Keating S, Minkoff H, Holman S, Crystal HA. Leptin, adiponectin and cognition in middle-aged HIV-infected and uninfected women. The Women’s Interagency HIV Study. J Gerontol Geriatr Res, 2015;4:240, Epub.

4. Gustafson D, Skoog I, Rosengren L, Zetterberg H, Blennow K. Cerebrospinal fluid beta-amyloid 1-42 may predict cognitive decline in older women. J Neurol Neurosurg Psychiatry. 2007;78:461-464.

3. Overweight and obesity increase risk for Alzheimer’s disease and the ageing brain.

Vascular risk factors, including obesity, increase risk for AD, however there is observed an ‘obesity paradox’ such that AD-related neuropathologies may lead to opposite observations in later life. Based on Swedish birth cohort studies, our first report in 2003 (Arch Internal Med, 2003;163:1524-1528) showed that being more overweight increased AD risk. Our 2003 report gave birth to an area of research that propelled the field in metabolic etiologies of AD. 1. Kiliaan AJ, Arnoldussen IA, Gustafson DR. Adipokines: a link between obesity and dementia? Lancet Neurol 2014; 13(9): 913-23.

2. Franx B, Arnoldussen I, Kiliaan A, Gustafson DR. Weight loss in patients with dementia: Considering the potential impact of pharmacotherapy. Drugs & Aging, 2017;34:425-436.

3. Besser LM, Gill DP, Monsell SE, Brenowitz W, Meranus D, Kukull W, Gustafson DR. Body Mass Index, weight change, and clinical progression in Mild Cognitive Impairment and Alzheimer’s Disease, Alz Dis Assoc Disorders, 2014;28(1):36-43. PMCID: PMC3945175 4. Gustafson D, Lissner L, Bengtsson C, Björkelund C, Skoog I. A 24-year follow-up of overweight and risk for temporal atrophy, Neurology, 2004;63:1876-1881. PMID: 15557505

4. Exploring genetic susceptibility to dementias and breast cancer, and associated risk factors.

Background: Genetic markers for aging outcomes such as dementia and obesity require further investigation.

1. Bäckman K, Joas E, Waern M, Östling S, Guo X, Blennow K, Skoog I, Gustafson DR. 37 years of body mass index and dementia: effect modification by the APOE genotype: Observations from the Prospective Population Study of Women in Gothenburg Sweden. J Alz Disease, 2015;48(4):1119-27. PMID: 26402098 2. Wang HX, Gustafson DR, Kivipelto M, Pedersen NL, Skoog I, Windblad B, Fratiglioni L. Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish Brain Power initiative. Neurobiol Aging 2012;33:1007.e1-7.

3. Zettergren A, Kern S, Gustafson D, Gudmundsson P, Sigström R, Östling S, Eriksson E, Zetterberg H, Blennow K, Skoog I. The ACE gene is associated with late-life major depression and age at dementia onset in a population-based cohort. Am J Geriatr Psychiatry. 2017; 25:170-177.

4. Gustafson DR, Melchior L, Eriksson E, Sundh V, Blennow K, Skoog I. The ACE Insertion Deletion polymorphism relates to dementia by metabolic phenotype, APOE4, and age of dementia onset. Neurobiol Aging, 2010;31:910-6. PMID: 18838196 Link to My NCBI Bibliography http://www.ncbi.nlm.nih.gov/sites/myncbi/deborah.gustafson.1/bibliograpahy/48969856/public/?sort=date&direc tion=ascending *Name change from Campbell to Gustafson in 1999. Gustafson is my birth name.

D. Research Support Ongoing Research Support U01 HL146202 Gustafson (Contact PI, mPI) & Wilson (mPI) 4/1/19-3/31/26 NIH/National Heart, Lung and Blood Institute MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) The goals of this multisite project are to address the unique and diverse characteristics of aging, urban, underrepresented men and women with or at-risk for HIV infection, and examine critical questions regarding clinical, behavioral, and epidemiological characteristics of HIV infection and associated comorbidities.

Research foci in the Bklyn CRS are cardiovascular, pulmonary, cognitive and brain imaging outcomes. Sex differences will also be addressed.

1 R01HL142116 French, PI; Gustafson, Site PI 5/1/18-4/30/21 NHLBI via subcontract with The Hektoen Institute for Medical Research The Contribution of Sleep and Circadian Disruption to Kynurenine Pathway Activation and Cardiometabolic Risk in Women with HIV The goals of this project are to study the associations between sleep/circadian disruption and TRP-KYN pathway activation and cardiometabolic disease risk in HIV+ women.

Recently Completed Research Support NIH/NIAID U01 1A131834 Gustafson & Minkoff (MPIs) 01/01/13 - 12/31/18 Women’s Interagency HIV Study (WIHS V) The major aims of this study are to examine the natural history and gynecological manifestations of HIV disease in women with and without HIV infection participating in a case-control cohort study entering its 5th cycle, years 20-25. Off the WIHS V parent grant, Dr. Gustafson is PI of supplements in the Brooklyn WIHS: Brooklyn Women's Interagency HIV Study (WIHS) V: FibroScan Supplement 1/1/16-12/31/16 Brooklyn Women's Interagency HIV Study (WIHS) V: Micro RNA Supplement 1/1/17-12/31/17 Brooklyn Women's Interagency HIV Study (WIHS) V: ECG, PFT, Echo Substudies 7/1/17-12/31/18 Brooklyn Women's Interagency HIV Study (WIHS) V: Microbiome Substudy 4/1/18-12/31/18 Brooklyn Women's Interagency HIV Study (WIHS) V: CVD Ascertainment 4/10/17-12/31/18 2013-2496 Skoog, PI; Gustafson, co-I 01/01/14-12/31/18 Swedish Council for Working Life and Social Research Programme Grant Ageing and Health Mental and cognitive health in relation to functional ability and multimorbidity in elderly persons. A life-time and birth cohort perspective.

OMB No. 0925-0001 and 0925-0002 (Rev. 11/16 Approved Through 10/31/2018)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Hirshfield, Sabina eRA COMMONS USER NAME (credential, e.g., agency login): HIRSHFIELD POSITION TITLE: Senior Research Scientist, Research & Evaluation EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION SUNY Binghamton, Binghamton, NY St. John’s University, Jamaica, NY Columbia University, New York, NY

DEGREE (if applicable) BA MA PhD

Completion Date MM/YYYY 05/1992 05/1995 09/2001

FIELD OF STUDY Sociology Sociology Sociomedical Sciences

A. Personal Statement I am a Principal Research Scientist in the STAR Program, which is in the Department of Medicine at SUNY Downstate Medical Center in Brooklyn, NY. My expertise is in online and app-based recruitment and conducting research and video-based interventions with vulnerable populations, including sexual minorities and those living with HIV. My training in social sciences and epidemiology has enabled me to conduct theoretically-based HIV prevention interventions with both HIV-negative and HIV-positive populations.

My current research focuses on HIV transmission risk behaviors among ethnically and racially diverse men who have sex with men (MSM), including home collection of biomarker data for viral load. I am currently a site PI for a CDC-funded multisite HIV prevention mobile messaging intervention for MSM (U01PS004977). And I am a site PI for a multisite study that will use mobile technology to deliver an evidence-based intervention to young (13-18 year old) MSM (U01MD011279). Of direct relevance to this proposal, (1) I am a Co-I on a multisite study to address intersectional stigma among 1,050 young Black and Latino MSM and transgender women (R01 MD013623): this study will test whether an online intervention tailored for intersectional stigma reduction can elicit online social support, promote intervention engagement, and mitigate the impact of multiple stigmas on HIV-related outcomes; and (2) I have collaborated on studies collecting biomarker data, including home administration of HIV tests and home collection of DBS for laboratory-quantified viral load. In addition, my quantitative skills and knowledge of HIV prevention methodologies are a perfect complement for the proposed study and team. In my role on the proposed study, I will work closely with the Department of Pathology at SUNY Downstate Medical Center to monitor DBS acute HIV testing and reporting to study participants.

1. Frye, V., Wilton, L., Hirshfield, S., Chiasson, M.A., Lucy, D., Usher, D., McCrossin, J., Greene, E., Koblin, B. (2018). Preferences for HIV test characteristics among young, black men who have sex with men (MSM) and transgender women: Implications for consistent HIV testing. PLoS One, 13:e0192936. PMCID: PMC5819791 2. Freeman, A.E., Sullivan, P., Higa, D., Sharma, A., MacGowan, R., Hirshfield, S., Greene, G.J., Gravens, L., Chavez, P., McNaghten, A.D., Johnson, W.D., Mustanski, B; eSTAMP Study Group.

(2018). Perceptions of HIV Self-Testing Among Men Who Have Sex With Men in the United States: A Qualitative Analysis. AIDS Educ Prev, 30:47-62. PMID: 29481298 3. Hirshfield, S., Teran, R., Downing, M.J., Chiasson, M.A., Van Tieu, H., Dize, L., Gaydos, C.A. (2018). Quantification of HIV-1 RNA Among Men Who Have Sex With Men Using an At-Home SelfCollected Dried Blood Spot Specimen: Feasibility Study. JMIR Public Health Surveill. 2018 Oct-Dec; 4(4): e10847. PMCID: PMC6238105 4. Frye, V., Wilton, L., Hirshfield, S., Chiasson, M.A., Usher, D., Lucy, D., McCrossin, J., Greene, E., Koblin, B. (2015) ‘‘Just Because It’s Out There, People Aren’t Going to Use It.’’ HIV self-testing among young, Black MSM and Transgender women in New York City. AIDS Patient Care STDS, 29:617-24. PMCID: PMC4808283.

B. Positions and Honors 1993-1995 Research Assistant, Albert Einstein College of Medicine 1993-1996 Mobile Unit Coordinator, Albert Einstein College of Medicine 1995-1998 Graduate Research Assistant, Adult Psychiatry, Columbia University 1997 Teaching Assistant, Epidemiology, Columbia University 1998-2000 Data Analyst, Adult Psychiatry, Columbia University 2000-2001 Research Consultant, Adult Psychiatry, Columbia University 2001-2006 Deputy Director, Research & Evaluation, Medical and Health Research Association 2006-2018 Senior Research Scientist, Research & Evaluation, Public Health Solutions 2018Principal Research Scientist, SUNY Downstate Medical Center Awards and Other Professional Activities 1999-2000 Sociomedical Sciences Fellowship, Award for doctoral research 2000-2001 Sociomedical Sciences Fellowship, Award for doctoral defense 2000 Eugene Litwak Award for dissertation proposal 2002-2006 Member, Columbia University Seminar, Drugs and Society 2010-2017 Member, Planning Council of New York, Needs Assessment Committee 2011Editorial Board, Archives of Sexual Behavior 2014-2017 Ad Hoc Reviewer, Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH), NIH 2015Ad Hoc Reviewer, Special Emphasis Panels, NIH 2018Chair, Community Health Advisory & Information Network (CHAIN) Study C. Contributions to Science 1. Internet-based behavioral research studies to address drug use and sexual risk in MSM. We began conducting online research after 9/11 to see whether men who were directly impacted by the terrorist attacks engaged in higher risk behaviors 3 months after the attacks, compared to 3 months before; findings confirmed this supposition. Our first internet study demonstrated the ability to reach and recruit large samples of urban and rural MSM online to complete surveys about sensitive topics, such as drug use and sexual risk. We found differential patterns of drug use by U.S. region and by self-reported HIV status. My role in these studies was study design, primary execution and collaboration with a team of experts. This work has provided evidence for legitimate new data sources in HIV prevention and consequently influenced the field. a. Hirshfield, S., Remien, R.H., Humberstone, M., Walavalkar, I., Chiasson, M.A. (2004). Substance Use and High-Risk Sex among Men Who Have Sex with Men: A National Online Study in the USA. AIDS Care, 16:1036-1047. b. Chiasson, M.A., Hirshfield, S., Humberstone, M., DiFilippi, J., Koblin, B.A., Remien, R.H. (2005).

Increased high risk sexual behavior after September 11 in men who have sex with men: An internet survey. Arch Sex Behav, 34:525-533. c. Yu, G., Wall, M.W., Chiasson, M.A., Hirshfield, S. (2015). Complex Drug Use Patterns and Associated HIV Transmission Risk Behaviors in an Internet Sample of US Men Who Have Sex with Men. Arch Sex Behav, 44(2):421-8. PMCID: PMC4381804. d. Hirshfield, S., Schrimshaw, E.W., Stall, R.D., Margolis, A.D., Downing, M.J Jr., Chiasson, M.A. (2015).

Drug Use, Sexual Risk, and Syndemic Production among Men Who Have Sex with Men Who Engage in Group Sexual Encounters. Am J Public Health, 105(9):1849-58.

2. Implementing online video-based intervention studies to reduce HIV transmission risk in MSM and to reduce unintended pregnancy in women.

In collaboration with colleagues, I have developed and implemented online, theoretically-based videos as a tool to educate MSM about HIV prevention and has demonstrated reductions in high risk behavior. My current online video-based intervention developed a 6-episode series called Just A Guy, about an HIV-positive man who struggles with medication adherence and HIV disclosure. This same theoretical framework has also been used successfully to increase awareness and improve attitudes towards IUDs in young women reached online.

I served as the primary investigator or co-investigator on all of these studies. a. Chiasson, M.A., Shuchat Shaw, F., Humberstone, M., Hirshfield, S., Hartel, D. (2009). Increased HIV disclosure three months after an online video intervention for men who have sex with men

(MSM). AIDS Care, 21:1081-1089. b. Hirshfield, S., Chiasson, M.A., Joseph, H., Scheinmann, R., Johnson, W.D., Remien, R.H., Shaw, F.S., Emmons, R., Yu, G., Margolis, A.D. (2012). An Online Randomized Controlled Trial Evaluating HIV Prevention Digital Media Interventions for Men who have Sex with Men. PLoS One, 7(10):e46252. PMCID: PMC3462792. c. Garbers, S., Chiasson, M.A., Baum, R., Tobier, N., Ventura, A., Hirshfield, S. (2015). “Get It And Forget It:” Online Evaluation of a Theory-Based IUD Educational Video in English and Spanish.

Contraception, 91(1):76-9. d. Hirshfield, S., Downing, M.J., Parsons, J.T., Grov, C., Gordon, R.J., Scheinmann, R., Houang, S.T., Sullivan, P.S., Linde, L., Anderson, I., Chiasson, M.A. (2016). Developing a video-based randomized controlled trial for HIV-positive gay, bisexual and other men who have sex with men. JMIR Research Protocols, 5(2):e125. PMCID: PMC4930529.

3. Research addressing HIV prevention and care in the digital era.

In addition to my contributions described above, with a team of collaborators, I have documented how the Internet provides another medium in which to conduct HIV prevention research, how digital media has begun to play a role in HIV prevention and care, and how the use of digital media interventions have great potential to cost-effectively meet the complex needs of diverse and often underserved populations living with or at high risk for acquiring HIV. This body of work also discusses disparities in the development of HIV risk reduction interventions that target ethnically diverse HIV-positive and HIV-negative MSM. a. Chiasson, M.A., Parsons, J.T., Tesoriero, J.M., Carballo-Dieguez, A., Hirshfield, S., Remien, R.H. (2006). HIV Behavioral Research Online. J Urban Health, 83(1):73-85. PMCID: PMC2258323. b. Chiasson, M.A., Hirshfield, S., Rietmeijer, C. (2010). HIV Prevention and Care in the Digital Age. J Acquir Immune Defic Syndr, 55:S94–S97. c. Hirshfield, S., Grov, C., Parsons, J., Anderson, I., Chiasson, M.A. (2015). Social Media Use and HIV Transmission Risk Behavior among Ethnically Diverse HIV-Positive Men who have Sex with Men: Results of an Online Study in Three U.S. States. Arch Sex Behav, 44(7):1969-78. d. Koblin, B.A., Nandi, V., Hirshfield, S., Chiasson, M.A., Hoover, D.R., Wilton, L., Usher, D., Frye, V. (2017). Informing the development of a mobile phone HIV testing intervention: Intentions to use specific HIV testing approaches among young Black MSM and transgender women. Journal of Medical Internet Research. 3(3):e45. PMCID: PMC5522583.

Complete List of Publications in MyNCBI https://www.ncbi.nlm.nih.gov/sites/myncbi/1P5mFSVsyjuQo/bibliography/41206336/public/?sort=date&directio n=descending D. Additional Information: Research Support and/or Scholastic Performance Ongoing Research Support R44 NR016908-01A1 Tan/Hirshfield (MPI) 08/01/2018-07/31/2020 A Tailored Approach to Promoting Engagement in Public Health Strata, a real-time web-based platform, will develop and tailor messages, based on psycho-demographic and other characteristics, to encourage minority participants to enroll in public health research studies. If successful, this technology will improve recruitment and enrollment of underrepresented minorities and help achieve representativeness in public health research studies.

Role: MPI R01 MD013623 Bauermeister/Muessig (MPI) 08/16/2018-03/31/2023 Increasing Engagement and Improving HIV Care Outcomes via Stigma Reduction in an Online Social Networking Intervention among Racially Diverse Young MSM and Transgender Women This study will test whether an online intervention tailored for intersectional stigma amelioration can elicit online social support, promote intervention engagement, and mitigate the impact of multiple stigmas on HIV-related outcomes. We will recruit and enroll 1,050 young (ages 15-29), Black and Latino US MSM and transgender women. Using a HIV-status stratified randomized trial design, participants will be assigned into one of 3 conditions (information-only control, a researcher-driven social network intervention, or a peer-driven social network intervention). The primary outcome is defined as successful engagement in care (consistent vs. for

HIV-positive participants and routine testing for HIV-negative participants). The AIMS are: 1) Test whether an online intervention that promotes user-generated content and engagement to address intersectional stigma is associated with improvements in the HIV prevention and care continuum (HIV testing, antiretroviral adherence, viral suppression) versus an information-only control arm; 2) Explore whether user engagement, as measured by quantitative and qualitative paradata, mediates the intervention’s stigma- and HIV care-related outcomes; and, 3) Examine how changes in intersectional stigma and improvements across the HIV care continuum vary between the researcher-driven vs. peer-driven social network intervention conditions.

Role: Co-Investigator U01 MD011279 Schnall/Garofalo (MPI) 09/01/16-04/30/21 A Pragmatic Clinical Trial of MyPEEPS Mobile to Improve HIV prevention Behaviors in Diverse Adolescent MSM The proposed MyPEEPS Mobile intervention is a novel and evidence-driven intervention using mobile technology to deliver HIV prevention information specifically developed for at-risk YMSM. This will be the first study to test the efficacy of a scaled-up, mobile version of an existing HIV prevention intervention originally developed for, designed by, and piloted for, a diverse group of YMSM. Role: Site PI/Co-investigator U01 PS004977 Sullivan (PI) 10/01/15-09/30/19 Mobile Messaging Intervention to Present New HIV Prevention Options for MSM This research proposes to develop HIV prevention messages based on rigorous preliminary qualitative studies, and reflecting the current age of combination biomedical and behavioral prevention. We will use mobile technology to test the messages among 1,200 MSM, and to provide links between targeted prevention services and service access points in Atlanta, Detroit, and New York.

Role: Site PI/Co-investigator Completed Research Support (past 3 years) R01MH100973-03S1 Hirshfield (PI) 07/10/16-12/31/18 (NCE) Feasibility of Collecting HIV Viral Load using Dried Blood Spots among HIV-positive men Among U.S. MSM living with HIV who are enrolled in an online, video-based risk reduction intervention, to assess the feasibility and acceptability of using a home dried blood spot (DBS) collection kit to quantify HIV viral load after 12-month follow-up, and to compare DBS-quantified HIV viral load to self-reported viral load.

Role: PI R01 MH100973 Hirshfield (PI) 01/01/14-12/31/18 (NCE) Scale-up of an Internet-delivered Randomized Controlled Trial for HIV+ Men This online video-based intervention is targeted to HIV+ MSM who have unprotected anal sex with partners who are HIV-negative or who do not know their HIV status. The goal of the intervention is to reduce unprotected sex with serodiscordant partners.

Role: PI R01 HD078595 Koblin (PI) 07/01/13-09/30/17 Using technology to match young Black MSM to HIV testing options This proposed research study seeks to address low HIV testing rates among young Black MSM by developing and testing a brief Internet-based HIV testing intervention optimized for mobile devices.

Role: Co-investigator H97 HA24967 HRSA Molano (PI) 09/01/12-08/31/17 Enhancing Engagement and Retention in Quality HIV Care for Transgender Women of Color Under the SPNS Program, Community Healthcare Network is implementing the Transgender Women Engagement and Entry to Care Project in Queens. The project is a peer-based model of outreach and engagement designed to increase access to and retention in quality HIV primary care for transgender women of color in New York City.

Role: Evaluator

R01 NR015737-01A1 Schnall (PI) 10/01/15-03/30/17 Video Information Provider for HIV-Associated Non-AIDS (VIP-HANA) Symptoms The goal of the proposed study is to develop and test an intervention, the VIP-HANA system, a web application that delivers self-care strategies tailored to HIV-Associated Non-AIDS conditions.

Role: Co-investigator

OMB No. 0925-0001 and 0925-0002 (Rev. Rev. 9/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH NAME: Tonya N. Taylor eRA COMMONS USER NAME (credential, e.g., agency login): TONYATAYLOR POSITION TITLE: Assistant Professor, College of Medicine, Division of Infectious Disease EDUCATION/TRAINING INSTITUTION AND LOCATION

DEGREE

Completion Date

FIELD OF STUDY

Boston University, Boston, MA

BA

05/1990

International Relations, Political Science, Spanish

University of Pennsylvania, Philadelphia, PA

MA

05/1998

Anthropology

University of Pennsylvania, Philadelphia, PA

Joint PhD

05/2005

Anthropology & Folklore

The HIV Center for Clinical and Behavioral Studies, Columbia University and the New York Psychiatric Institute, New York, NY

Postdoctoral

05/2009

Behavioral Science Research in HIV Prevention

Mailman School of Public Health, New York, NY

MS

05/2009

Biostatistics

Butler-William Scholar Program, National Institute of Aging, Bethesda, MD

Fellow

07/2013

Summer Institute on Aging Research

Advanced Research Institute (ARI) in Geriatric Mental Health (R25 MH068502; PI: M Bruce)

Fellow

04/2016

Career Development in Geriatric Mental Health and RO1 Guidance Preparation

A. Personal Statement: I am an Assistant Professor in the College of Medicine at SUNY Downstate Medical Center and a co-investigator in the MACS/WIHS Combined Cohort Study. My intellectual interests range across Medical and Linguistic Anthropology and Public Health, with a substantive focus on treatment-seeking behaviors, sexual and reproductive culture, and Aging. In 2009, I completed a 3-year T32 postdoctoral fellowship at the HIV Center for Clinical and Behavioral Studies at Columbia University and a MS in Biostatistics at the Mailman School of Public Health. I have extensive experience in the design and implementation of qualitative and survey research in the US and in Southern and Eastern Africa (mostly Zimbabwe and South Africa); recruiting and retaining significant numbers of study participants (n=1,034) within multiple multi-site studies in both the US and Africa (i.e., 3 WIHS sites; 12 rural sites in Zimbabwe). In 2011, I was awarded a NIMH Career Development Award to identify the prevention needs and sexual health of older women with HIV. In 2013, I became a Butler-William Scholar at the National Institute of Aging.

B. Positions and Honors Positions and Employment 1999-2000 2004-2006 2005-2006 2005-2006 2006-2009 2009-2011 2011-present

Graduate Assistant, African Studies Center, University of Pennsylvania Adjunct Lecturer, Department of Folklore and Folklife, University of Pennsylvania Adjunct Lecturer, Department of Anthropology, University of Pennsylvania Fellow, Critical Writing Program, University of Pennsylvania Post-Doctoral Fellow, HIV Center for Clinical and Behavioral Studies Columbia University/New York State Psychiatric Institute Research Instructor, Special Treatment and Research (STAR) Program, SUNY Downstate Assistant Professor, College of Medicine/ Division of Infectious Disease, SUNY Downstate

Other Professional Experience 2016 2015

Temporary Scientific Review Member, Behavioral and Social Science Approaches to Preventing HIV/AIDS (BSPH) Study Section Early Career Reviewer (ECR) Program, Center for Scientific Review at NIH

Honors/Awards 2005 2009

Kwame Nkrumah African Studies Prize for Best Dissertation, University of Pennsylvania.

HIV Center Publication Award for Junior Investigators and Fellows, for the article entitled “Comparison of HIV/AIDS-Specific Quality of Life at Western Medicine versus Traditional African Medicine Care Sites,” co-authored with Curtis Dolezal, Susan Tross, and William C. Holmes and published in Journal of Acquired Immune Deficiency Syndromes.

C. Contributions to Science 1. The Prevention Needs of Older Women Living with HIV (OWLH). With K01 support (KO1 MH095670; PI: Taylor), I conducted two studies using data from the Women’s Interagency HIV Study (WIHS), which is the largest longitudinal cohort study of HIV+ women and HIV- controls in the US, to identify the prevention needs of older (50+) OWLH. The research specific aims were to: 1) Describe the effects of aging on condomless sex among HIV-infected and HIV-uninfected women, aged 50 years and older; 2) Employ mixed methods to identify clinical, psychosocial, and interpersonal factors that account for variations in condomless sex among OWLH; and 3) Utilize information from aims 1 and 2 to develop and pilot test an Healthy HIV Aging intervention for OWLH using theory and evidence-based methods. Hazardous drinking among OWLH is an emerging problem. Using data from the WIHS, we assessed utilization of any alcohol treatment in the past 6 months among HIV+ women with hazardous drinking and performed multivariable logistic regression to determine correlates of receipt of any alcohol treatment. a) Taylor, T. N., Weedon, J., Golub, E. T., Karpiak, S. E., Gandhi, M., Cohen, M. H., Levine, A.M., Minkoff, H.L., Adedimeji, A.A., Goparaju, L., Holman, S., Wilson, T. E. (2014). Longitudinal Trends in Sexual Behaviors with Advancing Age and Menopause among Women with and Without HIV-1 Infection. AIDS and Behavior, 1-10. PMID: 25245474 b) Taylor, T. N., Munoz-Plaza, C. E., Goparaju, L., Martinez, O., Holman, S., Minkoff, H. L.... & Wilson, T. E. (2016). “The Pleasure Is Better as I’ve Gotten Older”: Sexual Health, Sexuality, and Sexual Risk Behaviors among Older Women Living with HIV. Archives of sexual behavior, 1-14. PMID: 27220311 c) Rubtsova, A. A., Kempf, M. C., Taylor, T. N., Konkle-Parker, D., Wingood, G. M., & Holstad, M. M. (2017). Healthy Aging in Older Women Living with HIV Infection: A Systematic Review of Psychosocial Factors. Current HIV/AIDS Reports, 14(1), 17-30. d) Hu, X., Harman, J., Winterstein, A. G., Zhong, Y., Wheeler, A. L., Taylor, T. N., ... & Adimora, A. A. (2016). Utilization of Alcohol Treatment among HIV-Positive Women with Hazardous Drinking.

Journal of substance abuse treatment, 64, 55-61. PMID: 26961420.

2. HIV Prevention to Reduce Health Disparities in Underserved Communities. In the US, I served as a collaborator on a CDC-funded study, led by my primary K01 mentor (Wilson), entitled “Barbershops as Behavioral Settings for HIV Prevention Targeting African American Heterosexual Men” that explored sexual risk behaviors among men of African descent residing in Brooklyn, NY. The formative phase of the study was used to develop a theoretically grounded and community-based HIV prevention program (Barbershop Talk with Brothers (BTWB) program) that seeks to improve individual skills and motivation to decrease sexual risk, and that builds men’s interest in and capacity for improving their community’s health. In 2011, we piloted the program with 80 men and found that the evaluation procedures were feasible to implement, and assessments indicate that behavioral outcomes and proposed mediators changed in hypothesized directions. With my KO1 mentor, Stephen Karpiak, I conducted several literature reviews on HIV prevention and the use of high impact prevention methods with older adults with and at risk for HIV infection. a) Taylor, T.N., Joseph, M.A., Henny, K.D., Pinto, A.R., Agbetor, F., Camilien, B., Williams, K.M., Browne, R.C., White, M., Gousse, Y., Brown, H., Taylor, R.D., Wilson, T.E. (2014). Perceptions of HIV Risk and Explanations of Sexual Risk Behavior Offered by Heterosexual Black Male Barbershop Patrons in Brooklyn, NY. Journal of Health Disparities Research and Practice, 7(6), 1. PMID: 25699198 b) Wilson, T. E., Fraser-White, M., Williams, K. M., Pinto, A., Agbetor, F., Camilien, B., Henny, K., Browne, R., Gousse, Y., Taylor, T., Brown, H., Taylor, R., Joseph, M. A. (2014). Barbershop Talk with Brothers: Using Community-Based Participatory Research to Develop and Pilot Test a Program to Reduce HIV Risk among Black Heterosexual Men. AIDS education and prevention: official publication of the International Society for AIDS Education, 26(5), 383. PMID: 25299804. c) Taylor, Tonya N., and Stephen Karpiak (2014). "HIV prevention in persons 50 and older." Encyclopedia of AIDS: 1-9. d) Taylor, T. and Karpiak, S.E. (2016) “PrEP and the Older Adult with HIV.” (2016). Mission, HIV-Age at http://hiv-age.org/2016/02/23/prep-and-the-older-adult-with-hiv/ 3. Traditional Medicine and HIV/AIDS in Rural Zimbabwe. With R03 support (RO3 MH062250; PI) I implemented a 15-month mixed method study on the use of traditional medicine in the care and treatment of people with HIV/AIDS in Chipinge, Zimbabwe. I recruited 400 patients and collected 400 baseline narratives, 254 follow-up interviews, 1300 quality of life (QoL) surveys, and videotaped 345 examples of traditional healing interventions. I culturally adapted the HIV/AIDS-Targeted Quality of Life (HAT-QoL) and the Medical Outcomes Study HIV Health Survey (MOS-HIV) instruments for use among Shona speakers in rural Zimbabwe. I collaborated with Drs. Tross, Dolezal, and Holmes to assess the reliability and construct validity of the HAT-QoL and the MOS-HIV adapted for use in Shona speaking rural Zimbabwe. In another study, we examined changes in self-reported health status resulting from Traditional African Care (TAC) and western medical care (WC) sites using data from 254 patients from the larger sample. Using these data, we found that the use of performance and emic explanatory models, intrinsic to traditional medicine, produced significantly better QoL outcome in individuals using both traditional and allopathic medicine, as compared to those who used only allopathic treatment.

These data strongly suggest that the potential benefit of integrating TAC sites in ART rollout programs— particularly in resource-poor settings—may go well beyond cultural sensitivity to impact on health itself and the likely related issues of ART adherence. a) Taylor, Tonya N. (2007). A Place of Troubles: The Political Ecology of HIV/AIDS in Chipinge, Zimbabwe. Safundi, 8 (2), 223 – 256. b) Taylor, Tonya N. (2010). “Because I was in Pain:” The Performance of Healing in the Care and Treatment of HIV/AIDS in rural Zimbabwe. Journal of American Folklore, 123 (489), 304-328. PMID: 20684086. c) Taylor, Tonya N., Dolezal, C, Tross, S Holmes, W. (2009). The Reliability and Validity of Two HIV/AIDS- specific quality of life instruments with a presumptive HIV+ population in rural Zimbabwe.

AIDS Care, 21(5), 598-607. PMID: 19444668. d) Taylor, Tonya N., Dolezal, C, Tross, S Holmes, W. (2008). Comparison of HIV/AIDS- specific Quality of Life Change in Zimbabwean Patients at Biomedical versus Traditional Medicine Care Sites. J Acquir Immune Defic Syndr, 49(5), 552-6. PMID: 18989225

4. Qualitative Research on Health Disparities. Research has shown that global health disparities, such as inequalities in social and health status, disease distribution, and access to services, exacerbated vulnerability to sickness and disease in resource poor communities. However, the ways in which health disparities contribute to different health outcomes are not well researched or understood. My research endeavors to address this critical gap in understanding through qualitative research methods how structural inequalities undermine the therapeutic choices pursued among disenfranchised communities in the US and Africa. I have collaborated on several randomized, multi-level structural interventions and mixed methods studies to address disparities in sexual and reproductive health services, self-care management of heart disease, sleep apnea and internalized homophobia. a) Taylor, TN., Mantell, J.E., Nywagi, N., Cishe, N., Cooper, D. (2014). “He lacks his fatherhood”: Assisted reproductive technologies and the biological imperative of fatherhood among Xhosa-speaking men living with HIV in South Africa. Culture Health and Sexuality, 15(9), 1101-1114. PMID: 23862770 b) Pekmezaris, R., Schwartz, R.M., Taylor T.N., DiMarzio, P., Nouryan, C., Murray, L., McKenzie, G., Ahern, D., Castillo, S., Pecinka, K., Bauer, L., Orona, T., Makaryus, A. (20016). A qualitative analysis to optimize a telemonitoring intervention for heart failure patients from disparity communities. (In press).

Medical Informatics and Decision Making. c) Shaw, R., McKenzie, S., Taylor, T., Olafiranye, O., Boutin-Foster, C., Ogedegbe, G., Jean-Louis, G. (2012).

"Beliefs and attitudes toward OSA evaluation and treatment among Blacks." Journal of the National Medical Association, 104(11-12), 510-9. PMID: 23560353 d) Valera, Pamela, & Taylor, Tonya. (2011). The religious experiences of Black married men who have sex with men. Journal of Black Psychology, 42(1), 106-22. PMID: 21280379.

Complete list of published work in MyBibliography: http://www.ncbi.nlm.nih.gov/sites/myncbi/1F35xsfAhJ0k5/bibliography/45854885/public/?sort=date&directio n=ascending D. Research Support.

Ongoing Research Support HRSA-19-008 (Cohen and Reinhardt, mPI) 7/1/19-6/30/24 Health Resources and Services Administration Geriatrics Workforce Enhancement Program To develop a new interprofessional geriatric curriculum and training program for physicians, nurses, and other members of the health care team to provide the highest level of integrated physical and mental health services and geriatric care and for older adults.in Brooklyn.

Role: Co-Director U01HL146202 Gustafson & Wilson (mPI) 4/1/2019-3/31/2026

National Heart, Lung and Blood Institute

MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) The major aims of this study are to examine the clinical, behavioral, and epidemiological characteristics of HIV infection and associated comorbidities in women and men as they age.

Role: Co-Investigator 1R21NR018348-01 (Wilson) 7/1/18-6/30/20 National Institute of Nursing Research Title: Positive Affect Promotion to Empower Optimal Adherence to HIV Therapy To develop knowledge regarding mechanisms linking positive affect and ART adherence through a feasibility pilot test of a positive affect induction intervention conducted among men and women with HIV-1 infection.

Role: Co-Investigator, Lead Qualitative components

FWA0002505 (Pekmezari) 8/11/18-6/10/23 Patient-Centered Outcomes Research Institute (PCORI) Patient and Caregiver-Centered Diabetes Telemanagement Program for Hispanic/Latino Patients A randomized Type 2 Diabetes management intervention using telemanagement for Hispanic/Latino disparity patients Role: Consultant Recently Completed Research Support 1A131834 (Minkoff and Gustafson) 7/1/17-12/31/18 National Institute on Minority Health and Health Disparities (NIMHD) Women’s Interagency HIV Study supplement (Turan, PI) Title: Effects of stigma and discrimination on patient-provider interactions and engagement in HIV care.

To examine the impact of stigma in health care among women with HIV. Role: Co-Investigator, Lead on the Brooklyn site qualitative study 1A131834 (Minkoff and Gustafson) 3/1/92-12/31/18 National Institute of Allergy and Infectious Diseases Women’s Interagency HIV Study This study examines the natural history and gynecological manifestations of HIV disease in women.

Role: Co-Investigator 5R34DA037129-03 (Aronson) 7/01/14-6/30/18 National Development & Research Institutes Increasing HIV Testing in Urban Emergency Departments via Mobile Technology Role: Consultant L30 AG043169 7/1/12-6/30/18 National Institute of Aging (NIA) HIV Prevention Need of Older Women with HIV NIH Loan Repayment Program Clinical Research Extramural 1 K01 MH095670-01 (Taylor) 7/11/11-4/30/17 National Institute of Mental Health (NIMH) HIV Prevention Need of Older Women with HIV Use data from the Women’s Interagency HIV Study to develop and pilot test a prevention program for older women with HIV. Role: Principal Investigator President’s Health Disparities Grant (Taylor) 7/1/15-6/31/17 SUNY Downstate Medical Center Prevention Needs of Older Men with HIV Assess the sexual health needs of older and younger men with and without HIV and identify determinants of sexual risk behaviors as men age.

Role: Principal Investigator

OMB No. 0925-0001 and 0925-0002 (Rev. 9/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Tracey E. Wilson eRA COMMONS USER NAME (credential, e.g., agency login): TWilson POSITION TITLE: Distinguished Service Professor, SUNY Downstate Medical Center EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

Siena College, Loudonville NY

BA

06/1989

Psychology

SUNY Albany, Albany NY

PhD

06/1996

Cognitive Psychology

Postdoctor al

09/1998

HIV/STD Prevention

MAPP

06/2014

Applied Positive Psychology

INSTITUTION AND LOCATION

Centers for Disease Control and Prevention/Assoc of Teachers of Preventive Medicine, Atlanta GA University of Pennsylvania, Philadelphia PA

FIELD OF STUDY

A. Personal Statement I am highly qualified to serve as a faculty member for the New York State International Training and Research Program, given my extensive mentoring experience with graduate students and postdoctoral fellows both domestically and internationally. My training is as a behavioral scientist with several decades experience leading federally funded programs that seek to promote healthy behaviors, increase care-seeking for HIV and other chronic conditions, and improve adherence and engagement in care in diverse populations. As part of these projects, I have effectively ensured active community engagement; successfully developed, pre-tested and implemented intervention and evaluation protocols; developed evaluation instruments; overseen implementation of research in the field; and disseminated the results of these trials to stakeholders while adhering to timelines, budgets, and research plans. I have also leveraged my experience as a research investigator to support the training of underrepresented minority students at the undergraduate, graduate, postdoctoral, and junior faculty levels and to support all trainees in the conduct of developing rigorous, ethical and applied study questions that build on individual and community strengths, and which seek to improve overall health and eliminate health inequities. These trainees have gone on to successful careers in academia, medicine, and applied public health. For the New York State International Training and Research Program, I can contribute to the success of the program through 1) providing mentorship to trainees, 2) participating in program conference calls and workshops, 3) and contributing input to educational program development.

B. Positions and Honors Positions and Employment 2000-2008 Assistant Professor of Clinical Sociomedical Sciences, Department of Sociomedical Sciences, Columbia University School of Public Health, New York, NY 1999-2005 Assistant Professor, Department of Preventive Medicine and Community Health, SUNY Downstate Medical Center, Brooklyn, NY 2005-2008 Associate Professor, Department of Preventive Medicine and Community Health, SUNY Downstate Medical Center, Brooklyn, NY 2008-2012 Associate Professor, Department of Community Health Sciences, School of Public Health, SUNY Downstate Medical Center, Brooklyn NY

2012-2018

Professor, Department of Community Health Sciences, School of Public Health, SUNY Downstate Medical Center, Brooklyn NY 2018-present Distinguished Service Professor, Department of Community Health Sciences, School of Public Health, SUNY Downstate Medical Center, Brooklyn NY Other Experience, selected 2012 Fellow, American Academy of Health Behavior 2015 Inaugural Alfred Stracher Faculty Recognition Award for Active Research in Involving Serious Illness and Mentoring Faculty in Research and Professional Development, State University of New York, Downstate Medical Center 2016 Faculty Member, Beta Iota Chapter of Delta Omega, National Public Health Honor Society 2018 Champion of Diversity Award, SUNY Downstate Medical Center 2004-present Journal of Community Health, Editorial Board 2012-present American Journal of Health Behavior, Review Board 2013-present Health Behavior and Policy Review, Associate Editor 2017 Member, NIH Special Emphasis Review Panel, PrEP Engagement and Retention Among Populations at High Risk for HIV Infection (ZRG1 AARR 51).

2018 Member, NIH Special Emphasis Review Panel, Prevention and Treatment Research to Address HIV/AIDS Disparities in women in the US (ZMD1 MLS (O1) C. Contributions to Science 1. Community-engaged prevention research. I have served as the PI and a collaborator on several public health initiatives that utilized community-engaged research principles to inform intervention development, implementation, evaluation, and dissemination efforts. I currently serve as the research core co-director of the Brooklyn Health Disparities Center, a collaboration between SUNY Downstate, the Arthur Ashe Institute for Urban Health, Inc., and the Brooklyn Borough President’s Office. I have recently completed service as the PI for an NIH-funded cluster randomized trial for that project, implemented among 860 men recruited from barbershops located in Brooklyn, NY neighborhoods with a high HIV prevalence. This cluster randomized trial resulted from three years of community collaboration on a CDC-funded project on which I served as the PI; during that time I served as a team leader and central organizer of a team of communitybased organizations, potential intervention consumers, and academics in the development and pilot testing of the program. In a subsequent NIH-funded cluster randomized trial of 860 men recruited from 57 barbershops, and with a 76% 6 month retention rate, we found a decrease in condomless sex (AOR=1.61, 95%CI 1.05, 2.47), adjusting for substance use, incarceration history, housing stability, nativity, socioeconomic status, and barbershop venue. a. Wilson TE, Gousse Y, Joseph MA, Browne RC, Camilien B, McFarlane D, Mitchell S, Brown H, Urraca N, Romeo D, Johnson S, Salifu M, Stewart M, Vavagiakis P, Fraser M.HIV Prevention for Black Heterosexual Men: The Barbershop Talk with Brothers Cluster Randomized Trial. Am J Public Health. 2019 Aug;109(8):1131-1137. doi: 10.2105/AJPH.2019.305121. Epub 2019 Jun 20. PubMed PMID: 31219715; PubMed Central PMCID: PMC6611102. b. Wilson TE, Fraser-White M, Williams KM, Pinto A, Agbetor F, Camilien B, Henny K, Browne RC, Gousse Y, Taylor T, Brown H, Taylor R, Joseph MA. Barbershop Talk With Brothers: using community-based participatory research to develop and pilot test a program to reduce HIV risk among Black heterosexual men. AIDS Educ Prev. 2014 Oct;26(5):383-97. PMCID: PMC4208304. c. Wilson TE, Fraser-White M, Feldman J, Homel P, Wright S, King G, Coll B, Banks S, Davis-King D, Price M, Browne R. Hair salon stylists as breast cancer prevention lay health advisors for African American and Afro-Caribbean women. J Health Care Poor Underserved. 2008 Feb;19(1):216-26. d. Dill LJ, Gousse Y, Huggins K, Fraser MA, Browne RC, Stewart M, Salifu M, Joseph MA, Wilson TE. Adjournment in Community HIV Prevention: Exploring Transitions in Community-Academic Partnerships. Health Promot Pract. 2019 Apr 3;:1524839919839361. doi: 10.1177/1524839919839361. [Epub ahead of print] PubMed PMID: 30943792; NIHMSID:NIHMS1014390.

2. Social and behavioral determinants of engagement in care among women. Much of my work has explored identification of social and behavioral factors linked to access to care and to medication adherence and retention in care. In addition to identifying modifiable variables that can improve the continuum of HIV care, this work sheds light on the intersection of race/ethnicity, gender, and SES as they inform prevention efforts in the U.S. More recently, I have explored the role of psychosocial assets on chronic disease management. a. Wilson TE, Weedon J, Cohen MH, Golub ET, Milam J, Young MA, Adedimeji AA. Cohen J, Fredrickson BL. Positive affect and its association with viral control among women with HIV infection.

2017 Jan;36(1):91-100. PMCID: PMC5209281. b. Wilson, TE, Kay ES, Turan B, Johnson MO, Kempf MC, Turan JM, Cohen MH, Adimora AA, Pereyera M, Golub ET, Goparaju L, Murchison L, Wingood GM, Metsch LR. Healthcare empowerment and viral control: The mediating effects of adherence and retention in care. Am J Prev Med. 2018 Apr 12. pii: S0749-3797(18)31572-1. [in press]. PMC Journal - In Process. c. Zhang Y, Wilson TE, Adedimeji A, Merenstein D, Milam J, Cohen J, Cohen M, Golub ET. The impact of substance use on adherence to antiretroviral therapy among HIV-infected women in the United States. AIDS and Beh. 2018: 22(3): 896-908. PMCID: PMC5709246. Cressman AE, Howe CJ, Nunn AS, Adimora AA, Williams DR, Kempf MC, Chandran A, Wentz EL, Blackstock OJ, Kassaye SG, Cohen J, Cohen MH, Wingood GM, Metsch LR, Wilson TE. The Relationship Between Discrimination and Missed HIV Care Appointments Among Women Living with HIV. AIDS Behav. 2019 May 2;. doi: 10.1007/s10461-019-02522-8. [Epub ahead of print] PubMed PMID: 31049811; NIHMSID:NIHMS1043034.

3. Interventions to improve outcomes in the HIV care continuum. I have worked on several interventions that have been demonstrated to improve outcomes for men and women along the HIV care continuum.

For example, I served as the PI on the CDC-funded Stay Connected program, designed to improve HIV retention in care. This study evaluated the impact of a clinic-wide retention strategy, and a nested trial of a tailored and provider-led counseling strategy. For the clinic-wide effort, more patients kept 2 consecutive visits within 12 months of the program as compared to the pre-intervention period (52.7% vs. 49.3%; 7% adjusted relative improvement: 7%, p< 0.001); for the nested component of the project, we conducted a randomized, controlled trial to promote enhanced contact focused on retention messages. We included 1838 new patients or those with a history of inconsistent clinic attendance, who were randomized to 1 of 3 arms: enhanced contact with interventionist (EC) (brief face-to-face meeting upon returning for care visit, interim visit call, appointment reminder calls, missed visit call); EC + skills (organization, problem solving, and communication skills); or SOC only. Log-binomial risk ratios comparing intervention arms against the SOC arm demonstrated better outcomes in both the EC and EC + skills arms (visit constancy: risk ratio [RR], 1.22 [95% CI, 1.09-1.36] and 1.22 [95% CI, 1.09-1.36], respectively; visit adherence: RR, 1.08 [95% CI, 1.05-1.11] and 1.06 [95% CI, 1.02-1.09], respectively; all Ps < .01). This project was selected by the CDC for dissemination as an evidence-informed practice for promoting retention in HIV care (https://www.cdc.gov/hiv/pdf/research/interventionresearch/compendium/lrc/cdc-hiv-lrc-stayconnected.pdf). a. Gardner LI, Marks G, Patel U, Cachay E, Wilson TE, Stirratt M, Rodriguez A, Sullivan M, Keruly JC, Giordano TP. Gaps up to 9 Months Between HIV Primary Care Visits Do Not Worsen Viral Load.

AIDS patient care and STDs. 2018; 32(4):157-164. b. Gardner LI, Marks G, Wilson TE, Giordano TP, Sullivan M, Raper JL, Rodriguez AE, Keruly J, Malitz F. Clinic-wide Intervention Lowers Financial Risk and Improves Revenue to HIV Clinics Through Fewer Missed Primary Care Visits. J Acquir Immune Defic Syndr. 2015 Apr 1;68(4):472-6. PubMed PMID: 25559605. c. Gardner LI, Giordano TP, Marks G, Wilson TE, Craw JA, Drainoni ML, Keruly JC, Rodriguez AE, Malitz F, Moore RD, Bradley-Springer LA, Holman S, Rose CE, Girde S, Sullivan M, Metsch LR, Saag M, Mugavero MJ; Retention in Care Study Group. Enhanced personal contact with HIV patients improves retention in primary care: a randomized trial in 6 US HIV clinics. Clin Infect Dis. 2014 Sep 1;59(5):725-34. PubMed PMID: 24837481. d. Mugavero MJ, Westfall AO, Zinski A, Davila J, Drainoni ML, Gardner LI, Keruly JC, Malitz F, Marks G, Metsch L, Wilson TE, Giordano TP; Retention in Care (RIC) Study Group. Measuring retention in

HIV care: the elusive gold standard. J Acquir Immune Defic Syndr. 2012 Dec 15;61(5):574-80. PMCID: PMC3508092.

4. Reducing sexual risk among men and women with HIV/STI. I was the PI for the CDC-funded Optimizing Partner Notification Study, which sought to reduce rates of infection among 600 men and women diagnosed with Neisseria gonorrhoeae or Chlamydia trachomatis. I designed the intervention and evaluation instruments, oversaw implementation in the field, and worked with a team of investigators on dissemination of study findings. Participants completed an interview at baseline and 6 months and checked for gonorrhea or chlamydial infection via nucleic acid amplification testing of urine. At follow-up, gonorrhea or chlamydial infection was detected in 6% of those randomly assigned to intervention and 11% of control participants (AOR=2.2; 95% CI=1.1-4.1). The program was selected by the HIV/AIDS Prevention Program Archive, funded by NIAID, for development of a replication kit as part of its collection of effective HIV prevention programs (https://www.socio.com/products/optimizing-partner-notification-open). As another example, I was PI of a CDC demonstration project on sexual risk among HIV-infected men and women (Positive STEPS). This project, which followed 767 patients, demonstrated that the 3-month prevalence of unprotected anal or vaginal sex declined significantly (p < 0.001) from baseline (42%) to 3 and 6 month follow-up (26% at first follow-up, 23% at second follow-up). Finally, I have been involved in several federally-funded studies that have focused on identifying the psychological and social determinants of sexual behavior among women living and/or at risk for acquiring HIV. a. Wilson TE, Hogben M, Malka ES, Liddon N, McCormack WM, et al. A randomized controlled trial for reducing risks for sexually transmitted infections through enhanced patient-based partner notification.

Am J Public Health. 2009 Apr;99 Suppl 1:S104-10. PMCID: PMC2724934. b. Gardner LI, Marks G, O'Daniels CM, Wilson TE, Golin C, Wright J, Quinlivan EB, Bradley-Springer L, Thompson M, Raffanti S, Thrun M. Implementation and evaluation of a clinic-based behavioral intervention: positive steps for patients with HIV. AIDS Patient Care STDS. 2008 Aug;22(8):627-35. c. Wilson TE, Feldman J, Vega MY, Gandhi M, Richardson J, Cohen MH, McKaig R, Ostrow D, Robison E, Gange SJ. Acquisition of new sexual partners among women with HIV infection: patterns of disclosure and sexual behavior within new partnerships. AIDS Educ Prev. 2007 Apr;19(2):151-9. d.

Hoffman S, Beckford Jarrett ST, Kelvin EA, Wallace SA, Augenbraun M, Hogben M, Liddon N, McCormack WM, Rubin S, Wilson TE. HIV and sexually transmitted infection risk behaviors and beliefs among Black West Indian immigrants and US-born Blacks. Am J Public Health. 2008 Nov;98(11):2042-50. PMCID: PMC2636422.

Complete list of published work in MyBibliography: http://www.ncbi.nlm.nih.gov/sites/myncbi/tracey.wilson.2/bibliography/41469485/public/?sort=date&direction=d escending D. Research Support Ongoing Research Support R21NR018348 (Wilson) National Institute of Nursing Research, NIH 7/19/18–6/30/20 Positive affect promotion to empower optimal adherence to HIV therapy This randomized feasibility study examines whether a three-session adherence intervention (Project APPEAL) improves HIV ART adherence through positive affective mechanisms of change.

Role: Principal Investigator U01HL146202 (Gustafson & Wilson) 4/1/19-3/31/26

National Heart, Lung and Blood Institute

MACS/WIHS Combined Cohort Study: Brooklyn Clinical Research Site (Bklyn CRS) The major aims of this study are to examine the clinical, behavioral, and epidemiological characteristics of HIV infection and associated comorbidities in women and men as they age.

Role: Principal Investigator

1S21MD012474-01 (Pato, Riley, Salifu) 9/14/17-8/31/22 National Institute on Minority Health and Health Disparities, NIH TRANSPORT – The Translational Program of Health Disparities Research Training This endowment award will establish a new and sustainable Translational Program of Health Disparities Research Training (TRANSPORT). TRANSPORT will provide a foundation for growing and developing a diverse biomedical research workforce that will position Downstate as a national leader in translational disparities and population health research. Our efforts will focus on recruiting and training underrepresented minority (URM) junior faculty, postdoctoral candidates and undergraduate students.

Role: Co-Investigator, Mentor R01MH10411401A1 (Turan) 2/19/15-12/31/19 National Institute of Mental Health Mechanisms and longitudinal effects of stigma on women’s adherence and outcomes This research will contribute to public health efforts to improve the health of women living with HIV, by conducting an in-depth examination of the effects of HIV-related stigma and discrimination.

Role: Consultant D43 TW010046-01A1 DeHovitz (PI) 4/1/16-3/31/21 Fogarty International Center KNMU-SUNY HIV Research Training Program The overall focus of this program is to provide necessary research training and in-country research capacity building to enhance care and reduce new HIV infections in Kazakhstan.

Role: Faculty Mentor Recently Completed Research Support P20MD006875 (Sub-Project ID: 5174; Wilson) 6/14/12—1/31/18 National Institute on Minority Health and Health Disparities, NIH Barbershop Talk HIV Prevention for African-American Men As a sub-project of the Brooklyn Health Disparities Center, this cluster randomized trial will test the efficacy of a CBPR-based behavioral intervention to reduce men’s HIV transmission risks.

Role: Principal Investigator P20MD006875 (Salifu, Fraser) 6/14/12—1/31/18 National Institute on Minority Health and Health Disparities, NIH The Brooklyn Health Disparities Center Center objectives are to foster community engaged research that contributes to the elimination of racial/ethnic health disparities in Brooklyn, New York.

Role: Co-Investigator, Research Core Co-Director, Executive Committee Member K01MH096770 (Taylor) 7/11/11—8/31/17 National Institute of Mental Health The prevention needs of older women with HIV The goal of this training grant is to support Dr. Taylor in developing an independent line of research to inform knowledge of the relationships between aging and sexual risk behavior among women.

Role in Grant: Primary Advisor/Mentor

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Jessica Eve Yager eRA COMMONS USER NAME (credential, e.g., agency login): jeyager POSITION TITLE: Assistant Professor, Division of Infectious Diseases EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

DEGREE (if applicable)

Completion Date MM/YYYY

Harvard University, Cambridge, MA

A.B.

06/1997

History and Literature

Yale University School of Medicine, New Haven, CT

M.D.

06/2005

Medicine

M.P.H.

12/2015

Epidemiology

INSTITUTION AND LOCATION

University of Washington, Seattle, WA

FIELD OF STUDY

A. Personal Statement The proposed research aims to evaluate various approaches to reducing tobacco use among individuals with HIV infection. As an Infectious Diseases provider who specializes in HIV management in a comprehensive outpatient setting, I am working constantly at the intersection of communicable diseases, chronic diseases, mental health, and addiction. Between 40% and 50% of our patients have ongoing tobacco use, and it is now well-recognized that in a population of individuals with controlled HIV infection, ongoing tobacco use leads to worse morbidity and mortality than does HIV infection. Recognizing the significant impact of tobacco use on the health outcomes of our patients, we are eager to participate in this study to determine best treatment modalities in this population. As the STAR Health Center (SHC) has been a leading local provider of interdisciplinary care for individuals living with or at high risk for HIV for over 25 years, we are well equipped and well situated to participate in this important and needed study. Additionally, as a founding site of the longrunning Womenâ&#x20AC;&#x2122;s Interagency HIV Study (WIHS), the STAR Program has extensive experience in coordinating different study types, including Randomized Controlled Trials. All research endeavors are supported by the STAR Program data team. Additionally, SUNY Downstate is the site of an institutional Clinical and Translational Science Center, which provides support and infrastructure to Downstate researchers.

I am currently the Clinical Director for the SHC Opioid Overdose Prevention Program. I am also the Program Director for multiple New York State AIDS Institute (AI) grants targeting different vulnerable populations within our clinic, include pregnant women and those returning home following incarceration, aiming to increase access to and retention in care. In addition, I have been working recently with the AIDS Institute and the Institute on Trauma and Trauma Informed Care to ensure that our clinic site and faculty function in accordance with the Best Practices of a Trauma-Informed site. Of particular relevance for the current proposal, I am site-PI for the Working with HIV Clinics to adopt Addiction Treatments using Implementation Facilitation (WHAT-IF?), a multi-site NIDA-funded study evaluating the delivery of substance use treatment in the primary care HIV-setting and I look forward to building on these collaborations with the current proposal. All of these roles and experiences make me uniquely suited to function as the Brooklyn site PI for A SMART Approach to Treating Tobacco Use Disorder in Persons Living with HIV. We are eager to help lead and develop the important and innovative research evaluating best-practices targeting smoking cessation in individuals with

HIV. By working together with Drs. Edelman and Bernstein and the investigative team, we look forward to contributing to the science and further expanding our own capacity and outreach.

As a junior faculty member at SUNY Downstate Medical Center, I am enthusiastic about the opportunity to work with colleagues and mentors on this significant work in order to further develop my own research and clinical impact. Given the extensive overlap of the epidemics of HIV risk and infection and tobacco use and the lack of data guiding best clinical practices, this project is both needed and timely.

B. Positions and Honors Positions and Employment 1998-2001 2005-2008

Research assistant, Immunobiology, Mount Sinai Medical School, New York, NY Intern and Resident Physician, Internal Medicine, University of California-San Francisco Medical Center, San Francisco General Hospital and the Veterans Affairs Medical Center, UCSF, San Francisco, CA 2008-2009 Research Fellow, Fogarty International Clinical Research Scholars and Fellows Program, Cochabamba, Bolivia 2009-2012 Fellow, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA 2012-present Assistant Professor, Division of Infectious Diseases, SUNY Downstate Medical Center, Brooklyn, NY 2017-present Chief of Service, Treatment for Life Center, Brookdale Hospital Medical Center Professional Certifications and Memberships 2008 2011 20092012-2018 2018-

Board Certified, American Board of Internal Medicine Board Certified, American Board of Infectious Disease Member, Infectious Disease Society of America Member, American College of Physicians Fellow, American College of Physicians

Honors 1993-1997 1997 1999 2004-2005 2005 2005

John Harvard and Harvard College Scholarships for academic achievement of high distinction Magna Cum Laude, Harvard University Degree with Honors in American History and Literature Student Research Fellowship, Crohn’s and Colitis Foundation of America Medical Student Research Fellowship, Yale University School of Medicine Norma Bailey Berniker Prize, Yale University School of Medicine, for the “promise of best exemplifying the disciplines and precepts of the Oath of Hippocrates and Maimonides Prayer” Medical Degree awarded with Honors

C. Contributions to Science 1. Food security and social determinants of health: In Uganda, I worked extensively on food security and the association between food insecurity and increased sexual risk taking behavior, HIV acquisition, and worse HIV outcomes among those infected with HIV. These efforts led to programmatic evaluations aiming to understand how to develop best practices addressing the synergistic epidemics of food insecurity and HIV. This work laid the foundation for many of my current efforts as I then developed a structural framework for understanding the complicated interplay between individual, familial, and societal factors, and their impact on health outcomes. a. Yager JE, Kadiyala S, Weiser SD. HIV/AIDS, Food Supplementation and Livelihood Programs in Uganda: A Way Forward? PLoS One 2011; 6:e26117.

2. Epidemiological cohort work and linkage to care: In central rural Bolivia, I helped establish a cohort of residents to conduct the first large-scale, community-based study of the prevalence of Chagas disease in over 20 years. Rural residents were engaged by the study team to link them to possible treatment and routine medical care, to which many had not had access. I undertook regular outreach to continue engaging

individuals in an attempt to bridge cultural and language barriers to allow them to access necessary medical care. Additionally, as an Infectious Diseases Fellow at the University of Washington, I worked in Kampala, Uganda developing a short message service (SMS) texting intervention to increase retention rates among cancer care patients. These efforts laid an early foundation for the ongoing work of engagement, linkage, and retention, with a focus on cultural awareness and sensitivity in all settings. a. Yager JE, Beltran DFL, Torrico F, Gilman RH, Bern C. Prevalence of Chagas Heart Disease in a Region Endemic for Trypanosoma Cruzi. Global Heart 2015; 10:145-150.

3. Diagnosis, treatment, and resistance: I have led or participated in multiple efforts focused on disease pathogensis, treatment, and resistance in the setting of different infectious conditions. These projects established a groundwork on which to build our medication assisted treatment for substance use disorders and biomedical HIV prevention efforts. a. Yager JE, Magaret AS, Kuntz S, Selke S, Huang ML, Corey L, Casper C, Wald A. Valganciclovir for the Suppression of Epstein-Barr Virus Replication. J Infect Dis 2017; 216:198-202. b. Yager JE, Ford ES, Boas ZP, Haseley LA, Cookson BT, SenGupta DJ, Fang FC, Gottlieb GS. Ureaplasma urealyticum CAPD-associated Peritonitis Diagnosed by 16S rDNA PCR. J Clin Microbiol 2010; 48:4310-4312. c. Englund J, Zerr D, Pergam S, Kuypers J, Yager J, Boeckh M, Mattson D, Whittington N, Whimbey E, Duchin J, Uyeki T, Deyde V, Okomo-Adhiambo M, Sheu T, Trujillo A, Klimov A, Gubareva L, Kay M. Oseltamivir-Resistant Novel Influenza A (H1N1) Virus Infection in Two Immunosuppressed Patients --- Seattle, Washington, 2009. MMWR Weekly 2009; 58:893-896.

D. Additional Information: Research Support and/or Scholastic Performance Ongoing Support 1H79TI080644-01; Yager (PD) 8/1/2017 - 7/31/2022 Substance Abuse and Mental Health Services Administration Brooklyn SUD Treatment Center for High-Risk Populations This program focuses on engaging young LGBTQ individuals and those returning home following incarceration who are either HIV-positive or at-risk for new HIV aquisition.

Role: Project Director 5689-02; Yager (PD) 8/1/2017 - 7/31/2022 New York State AIDS Institute Criminal Justice Initiative Corrections to Community Program This program seeks to improve linkage to and retention in care among HIV-positive individuals returning to the community following release from incarceration.

Role: Project Director R01 DA041067 Yager (PI) 9/30/2015 â&#x20AC;&#x201C; 8/31/2020 National Institute on Drug Abuse (Subcontract through Yale University) Working with HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation (WHAT-IF?) This multi-site study is studying the treatment of substance-use disorders in the setting of HIV primary care clinics.

Role: Site PI 5345-02 Yager (PD) 7/1/2016 - 6/30/2022 New York State AIDS Institute Family Focused HIV Care Program This program targets caregivers of young children and pregnant women for additional medical and case management support.

Role: Project Director

Completed Research Support R24 TW007988 Vermund (PI) 7/01/2008-06/30/2009 Fogarty International Clinical Research Scholars and Fellows Program As a Fogarty Fellow, I worked with Dr. Robert Gilman of Johns Hopkins University, Dr. Caryn Bern of the Centers for Disease Control and Dr. Faustino Torrico of the Universidad Mayor de San Simon in Cochabamba, Bolivia, a region endemic for Trypanosoma cruzi, designing and performing a community-based study of causes of cardiac disease.

Role: Fellow T21 CA080416 Linial (PI) NIH, Interdisciplinary Training in Cancer Research 7/1/2011 â&#x20AC;&#x201C; 7/1/2012 As a senior fellow at the University of Washington, my salary support was funded through a competitive training grant administered through the Fred Hutchinson Cancer Research Center and the University of Washington seeking to train post-graduate fellows in interdisciplinary research. I worked with Dr. Corey Casper and Dr. Beti Thompson on the use of short message service (SMS) among Ugandan cancer patients to improve adherence to cancer care and clinical outcomes.

Role: Fellow

OMB No. 0925-0001 and 0925-0002 (Rev. 09/17 Approved Through 03/31/2020)

BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors.

Follow this format for each person. DO NOT EXCEED FIVE PAGES.

NAME: Monica M. Parker eRA COMMONS USER NAME (credential, e.g., agency login): WADS096 POSITION TITLE: Chief, Laboratory of Bloodborne and Parasitic Diseases; Research Scientist 5 EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)

INSTITUTION AND LOCATION University at Albany University at Albany, School of Public Health Wadsworth Center

DEGREE (if applicable)

Completion Date MM/YYYY

B.S.

05/1984

Biology

Ph.D.

12/1997

Biomedical Sciences

Postdoctoral

11/1998

Bacteriophage Genetics

FIELD OF STUDY

A. Personal Statement My research focuses on 1) the development and validation of new laboratory methods to improve and expand access to HIV and hepatitis C virus (HCV) diagnostic testing and 2) applying molecular and immunologic laboratory techniques in cross-sectional analysis of HIV and HCV in different populations. I am also experienced in evaluating innovative laboratory technologies for infectious disease diagnostics, surveillance and public health-related investigations.

B. Positions and Honors Positions and Employment 1997-1998 Postdoctoral Research Affiliate, Division of Genetic Disorders, Wadsworth Center, Albany, NY 1998- 2004 Associate Director, Viral Genotyping Laboratory, Wadsworth Center, Albany, NY 1998-2005 Research Scientist 2, Wadsworth Center, New York State Department of Health, Albany, NY 2004-2008 Director, Viral Genotyping Laboratory, Wadsworth Center, Albany, NY 2005-2008 Research Scientist 3, Wadsworth Center, New York State Department of Health, Albany, NY 2006Lecturer, Department of Biomedical Sciences, University of Albany School of Public Health 2007Director, Bloodborne Viruses Laboratory, Wadsworth Center, Albany, NY 2008-2014 Research Scientist 4, Wadsworth Center, New York State Department of Health, Albany, NY 2008Chief, Laboratory of Bloodborne Diseases, Wadsworth Center, Albany, NY 2011-2019 Faculty Member, Wadsworth Center Master of Science in Laboratory Sciences Program 2014Research Scientist 5, Wadsworth Center, New York State Department of Health, Albany, NY Other Experience and Professional Memberships 2003New York State Certificate of Qualification - Clinical Laboratory Director in Virology (Molecular) 2009New York State Certificate of Qualification - Clinical Laboratory Director in Diagnostic Immunology (HIV and Viral Hepatitis Serology) 2007Delegate Member, Association for Public Health Laboratories

2009-2010 2010-2016 2010-2016 2011 20122014-2016 2018 -

Member (Cohort 2), National Center for Public Health Laboratory Leadership (NCPHLL) Emerging Leaders Program, Association for Public Health Laboratories Curriculum Chair, Wadsworth Center Master of Science in Laboratory Sciences Program Executive Committee Member, Wadsworth Center Master of Science in Laboratory Sciences Program Member, Hepatitis C Birth Cohort Recommendations External Workgroup, Centers for Disease Control and Prevention Chair, HIV/Viral Hepatitis Subcommittee, Association for Public Health Laboratories Co-Chair, 2016 HIV Diagnostics Conference Contributor and Voting Member of the Clinical Laboratory Standards Institute (CLSI) Document Development Committee for Document M53, Criteria for Laboratory Testing and Diagnosis of Human Immunodeficiency Virus Infection, 2nd Edition.

C. Contributions to Science My contributions include research and development of laboratory tests for HIV diagnosis and monitoring.

These studies include evaluation of serologic and molecular methodologies. These studies have contributed to the field of HIV diagnostics by contributing new methods to fill existing gaps and by evaluating the performance of established methods. a. Styer, L.S., Sullivan, T.J., Parker, M.M. Evaluation of an alternative supplemental testing strategy for HIV diagnosis by retrospective analysis of clinical HIV testing data. J Clin Virol 2011;52 Supplement 1:S35-S40. PMID: 22018662 b. Linley L, Ethridge SF, Oraka E, Owen SM, Wesolowski LG, Wroblewski K, Landgraf KM, Parker MM, Brinson M, Branson, Bernard M. Evaluation of supplemental testing with the Multispot HIV-1/HIV-2 Rapid Test and APTIMA HIV-1 RNA Qualitative Assay to resolve specimens with indeterminate or negative HIV-1 Western blots. J Clin Virol. 2013; 58S: e108-e112. PMID: 24342469 c. Luo W, Davis G, Li L, Shriver MK, Mei J, Styer LM, Parker MM, Smith A, Paz-Bailey G, Ethridge S, Wesolowski L, Owen SM, Masciotra S. Evaluation of dried blood spot protocols with the Bio-Rad GS HIV Combo Ag/Ab EIA and Geeniusâ&#x201E;˘ HIV 1/2 Supplemental Assay. J Clin Virol. 2017;91:84-89 PMID:28366544 d. Parker MM, Bennett SB, Sullivan TJ, Fordan S, Wesolowski LG, Wroblewski K, Gaynor AM. Performance of the Alere Determine HIV-1/2 Ag/Ab Combo Rapid Test with algorithm defined acute HIV-1 infection specimens. J Clin Virol. 2018;104:89-91. PMID:2980308 My previous work has included multi-site research projects conducted in collaboration with the CDC and with state and local health departments. These studies were designed to evaluate diagnostic test methods and strategies for detecting HIV infection, especially acute infection. These publications illustrate how different HIV diagnostic testing strategies impact detection of HIV and demonstrate the feasibility of utilizing a public health laboratory as a reference testing center to facilitate diagnosis of acute HIV infection. a. Patel, P., Mackellar, D., Simmons, P., Uniyal, A., Gallagher, K., Bennett, B., Sullivan, T., Kowalski, A., Parker, M.M., LaLota, M., Blank, S., Kerndt, P., Sullivan, P. for the Centers for Disease Control and Prevention Acute HIV Infection Study Group (2006-2008). Detecting acute human immunodeficiency virus infection using 3 different screening immunoassays and nucleic acid amplification testing for human immunodeficiency virus RNA. Archives of Internal Medicine 2010;170:66-74. PMID: 20065201 b. Patel, P., Bennett, B., Sullivan, T.J., Parker, M.M., Heffelfinger, J.D., Sullivan, P.S. for the CDC AHI Study Group. Rapid HIV screening: missed opportunities for HIV diagnosis and prevention. Journal of Clinical Virology 2012;54:42-7. PMID:22381919 c. Sullivan, T.J., Patel, P., Hutchinson, A., Ethridge, S.F., Parker, M.M. An evaluation of pooling strategies for acute HIV-1 infection screening using nucleic acid amplification testing. Journal of Clinical Microbiology 2011;49:3667-8. PMID:21832020 d. Wesolowski L.G., Wroblewski K., Bennett S.B., Parker MM, Hagan C., Ethridge S.F., Rhodes J., Sullivan T.J., Ignacio-Hernando I., Werner B.G., Owen S.M. Nucleic acid testing by public health referral laboratories for public health laboratories using the U.S. HIV diagnostic testing algorithm.

Journal of Clinical Virology 2015;65:6-10. PMID:25766979

My previous work has included molecular analysis of HIV and HCV for public health-focused research studies.

These include studies initiated by me as well as research conducted in collaboration with epidemiologists, behavioral scientists and virologists at other institutions. These studies demonstrate my skills in viral sequence analysis and my ability to collaborate with scientists from a variety of disciplines and institutions. a. Karchava, M., Pulver, W., Smith, L., Philpott, S., Sullivan, T.J., Wethers, J., Parker, M.M. Prevalence of drug-resistance mutations and non-subtype B strains among HIV-infected infants from New York State. Journal of Acquired Immune Deficiency Syndromes. 2006;42:614-619. PMID: 16868498 b. Parker, M.M., Gordon, D., Reilly, A., Horowitz, H.W., Waters, M., Bennett, R., Hallack, R., Smith, J., Lamson, D., Aydemir, A., Dvali, N., Agins, B.D., Drusano, G.L., Taylor, J. Prevalence of drug-resistant and non-subtype B HIV strains in antiretroviral-naive, HIV-infected individuals in New York State. AIDS Patient Care and STDs 2007;21:644-652. PMID: 17919091 c. Goldsamt, L.A., Clatts, M.C., Parker, M.M., Colon, V., Hallack, R., Messina, M.M. Prevalence of sexually acquired antiretroviral drug resistance in a community sample of HIV-positive MSM in New York City. AIDS Patient Care and STDs 2011;25:287-93. PMID: 21457055 d. Karchava M, Waldenström J, Parker M, Hallack R, Sharvadze L, Gatserelia L, Chkhartishvili N, Dvali N, Dzigua L, Dolmazashvili E, Norder H, Tsertsvadze T. High incidence of the hepatitis C virus recombinant 2k/1b in Georgia: Recommendations for testing and treatment. Hepatology Research.

2015;45:1292-8. PMID:25689487 My contributions also include assisting in over a dozen outbreak investigations of potential HCV transmission associated with healthcare procedures. I have assisted the New York State and New York City Departments of Health (DOH) by conducting sequencing of HCV extracted from patient blood samples and conducting phylogenetic analysis to identify closely related viruses indicative of a transmission link. In several cases, the sequence analysis conducted by my laboratory, together with epidemiologic data collected by the DOH, provided strong evidence of patient-to-patient transmission in health care facilities. a. Centers for Disease Control and Prevention. (2009) Hepatitis C Virus Transmission at an Outpatient Hemodialysis Unit-New York, 2001–2008. Morbidity and Mortality Weekly Report. 58(08):189-92. b. NYSDOH Board Professional Medical Conduct, Determination and Order. http://w3.health.state.ny.us/opmc/factions.nsf/58220a7f9eeaafab85256b180058c032/ad4e9d90aa7196 5b852575830061a449/$FILE/HRG%20139943.pdf. Dr. Parker’s testimony is documented on pages 2028 of Determination and Order document. c. Gutelius, B., Perz, J.F., Parker, M.M., Hallack, R., Stricof, R., Clement, E.J., Lin, Y., Xia, G., Punsalang, A., Eramo, A., Layton, M., Balter, S. (2010). Multiple Clusters of Hepatitis Virus Infections Associated with Anesthesia for Outpatient Endoscopy Procedures. Gastroenterology; 139:163-70.

PMID: 20353790 Complete list of published work in MyBibliography: https://www.ncbi.nlm.nih.gov/myncbi/monica.parker.2/bibliography/public/ D. Additional Information: Research Support and/or Scholastic Performance Ongoing Research Support Subcontract with City University of New York Parker (Subcontract PI) 4/15/18 – 4/15/21 Hepatitis C RNA Testing for Staying Safe Study Pedro Mateu-Gelabert (PI) The goal of this project is to conduct HCV RNA testing, next generation sequencing and transmission analysis of HCV from dried blood spots collected from young injection drug users enrolled in the Staying Safe study.

Subcontract with City University of New York Parker (PI) 10/21/17 – 6/30/20 HIV antibody testing for Together 5000 study Christian Grov (PI) The goal of this project is to provide HIV antibody testing from oral fluid specimens self-collected by participants enrolled in the Together 5000 study.

564002006411302 Parker (PI) Association for Public Health Laboratories

8/1/12-6/30/20

APHL HIV NAT Referral Demonstration Project The goal of this project is to serve as a reference laboratory for other public health laboratories in the United State that need access to HIV-1 nucleic acid testing (NAT) in order to diagnose acute HIV-1 infection.

Completed Research Support 200201353888 Parker (PI) 1/1/13-12/31/17 Centers for Disease Control and Prevention Title: Laboratory testing for HIV incidence surveillance-STARHS The goal of this project is to receive, store and test HIV-positive serum samples from all newly diagnosed individuals residing in 25 surveillance jurisdictions through the United States using a serological testing technology developed to estimate HIV incidence.

564002009421702 Parker (PI) 11/1/16-6/30/17 Association for Public Health Laboratories Title: HCV Sequencing and GHOST Utilization Pilot Study The goal of this project is to validate hepatitis C virus next generation sequencing and Global Hepatitis Outbreak and Surveillance Technology (GHOST) protocols and implement the optimized protocols on surveillance specimens in order to evaluate workflow and reporting practices.

200200824540C Parker (PI) 3/14/08-12/31/12 Centers for Disease Control and Prevention Title: Lab testing for recent HIV infection The goal of this project was to receive, store and test HIV-positive serum samples from all newly diagnosed individuals residing in 26 surveillance jurisdictions through the United States using a serological testing technology developed to estimate HIV incidence.

APHL Contract: Parker (PI) 10/18/10-6/30/11 Association for Public Health Laboratories Title: Supplemental HIV testing evaluation The goal of this project was to evaluate alterative diagnostic testing strategies that utilize rapid immunoassays and nucleic acid tests to confirm reactive HIV screening test results.