The Arbiter 2-22-11

Page 1

Issue no.

44

Volume 23

First Issue

FREE

February 22, 2011

arbiteronline.com

The Independent Student Voice of Boise State Since 1933

glenn landberg/THE ARBITER

In the center of the photo you’re looking deep into the x-ray photoelectron spectrometer, simply called “The Machine” by it’s users. A nano particle is of course too small to be seen with a human eye, so the machine uses differences in atmostpheric pressure to get a better look into the nature of nanoparticles.

Physics vs. Cancer

Using the strength of small, researchers investigate the potential of zinc oxide Suzanne Craig

Assistant News Editor Physics, the bane of many students, has been connected with cancer, one of the banes of humanity. It’s bizarre to think that what starts with math, number crunching and kinematics equations can produce a potential cure for cancer in the form of nanoparticles. Boise State professor Alex Punnoose, Ph.D., is leading a research team along with professor Denise Wingett that is looking into the potential uses for zinc oxide nanoparticles as a cure for cancer. Nanoparticles are, as the name implies, extremely small. A nanometer is defined as one billionth of a meter -- that’s the length of a few hundred atoms lined up at the most. There are two ways to make these

extremely small samples of materials. One way is to take a relatively large piece (usually in crystalized form) and break it. This produces many flaws and lots of them in the resulting nanoparticle. The other way is through chemical synthesis. “We make a solution and grow the crystals in it in a bottom-up approach, using other materials to halt the growth of the material when it is at the size we want,” Punnoose said. That growing of the nanoparticles is part of the undergraduate researchers jobs. There are nine at work on this project, each working on different types of nanoparticles. Some students have worked in the lab for more than two years, though not necessarily on this project. Josh Anghel, a senior physics major began doing research the summer after his freshman year when there were only two

projects being researched. “The one Doctor Punnoose was running seemed more interesting,” he said. Despite the production of multiple types of nanoparticles, the one that is receiving the most hype as a potential new form of treatment for cancer is zinc oxide. It’s a semiconductor usually used in the production of electronics but has been found to be toxic to certain cells and toxic bacteria. What started as a simple test on zinc oxide’s reaction to organic substances by Punnoose and Kevin Feris, Ph.D. an assistant professor for the department of biological sciences, became a lot more when it was found that zinc oxide killed harmful bacteria, such as E. coli and the bacteria responsible for staph infection. Moving onto human cells, the zinc oxide nanoparticles were tested on

jurkat cells, which are a type of cancerous immune system cell, as well as normal healthy immune system cells, with the help of Denise Wingett, cell biologist, Ph.D. and chair of the biology department. “We found that all cancer cells (that were tested) can be killed at a concentration where normal cells of the same family are not affected,” Punnoose said. These findings have already been published. The students who helped with the project were honored as co-authors. The next step is testing the zinc oxide on different types of cancerous cells, to be handled in Wingett’s lab with the help of her own student researchers. “We branched into testing breast and prostate cancer, and I am now looking at types of lung cancer,” said Janet Layne, a biology graduate student.

Another cool thing about the zinc oxide nanoparticles is that they aren’t all the same for each type of cancer. Surface charge and other characteristics of the nanoparticles are altered for each type and certain alterations produce higher toxicity for different kinds of cells. “We can tailor the properties of these nanoparticles to increase toxicity ... this is why other labs testing zinc oxide don’t necessarily get the same results, as it is not plain zinc oxide,” Punnoose said. The next step in the research process is animal testing. Permission for this has recently been obtained and is expected to begin soon with funding being partially supplied by the National Institute of Health. Efforts to obtain more funds in order to make zinc oxide nanoparticles a promising candidate for cancer therapy are underway.

Photos by glenn landberg/THE ARBITER

Left: Boone Beausoleil, a senior physics major, sets up a solution to be mixed in the lab. Right: is Aaron Thurber, lab manager and alumnus with a masters in physics, works with the x-ray photoelectron spectrometer.

What’s Inside

News Opinion Sports Culture

page page page page

2 3 4 7

Do you have a burning news tip? E-mail News@Arbiteronline.com or call 426-6300.

41º high

News Editor - Andrew Ford Assistant News Editor - Suzanne Craig

White Water Movie

SATURDAY!

Weather

Today

Tomorrow

Mostly Cloudy

chance of precip: 20%

37º high

Snow Showers

chance of precip: 30%

EVERY THURSDAY & FRIDAY >>>

Feb 26

“Wild Water” A shared passion An extraordinary world

BUY 1 FULL DAY TICKET GET 2ND FULL DAY TICKET 1/2 OFF

1/2 OFF DAY ticket when accompanied by a Tamarack SEASON PASS HOLDER $189 COLLEGE SEASON PASS

Lift + movie ticket combo $50 No Lines / Great Skiing / Best Price The Arbiter

GROUP RATES FOR RENTALS, LESSONS, & DAY TICKETS arbiteronline.com


Turn static files into dynamic content formats.

Create a flipbook
Issuu converts static files into: digital portfolios, online yearbooks, online catalogs, digital photo albums and more. Sign up and create your flipbook.