The Unification of General Relativity and Quantum Mechanics



▶ Credit: Pixabay
The bacteria in your mouth affect more than just your teeth and gums—they may also play a role in brain function. A study of 55 people with mild cognitive impairment (MCI) found that those with higher levels of Neisseria bacteria performed better on tests of working memory, executive function, and visual attention. Even among 60 cognitively healthy participants, a Neisseria-dominant oral microbiome correlated with stronger memory.
Led by researchers at the University of Exeter, the study suggests that supporting beneficial oral bacteria could help slow cognitive decline. Probiotics or prebiotics may encourage the growth of these microbes within weeks. These findings align with growing research linking oral health to dementia risk. Scientists have even discovered bacteria from gum disease in the brains of Alzheimer’s patients. However, not all oral microbes are harmful—
some may be protective. Similar to gut bacteria, maintaining a balanced oral microbiome is crucial. Neisseria species, commonly found in the mouth and nose, may offer health benefits, including lowering blood pressure by converting dietary nitrates into nitric oxide. This signaling molecule plays a key role in preventing gum disease, regulating blood pressure, and supporting brain health by enhancing neural plasticity and reducing inflammation—both important factors in Alzheimer’s prevention.
Genetic Risk for Alzheimer’s Linked to Prevotella-Dominant Oral Microbiome
People genetically predisposed to Alzheimer’s often struggle to produce nitric oxide naturally. In this study, molecular biologist Joanna L’Heureux and her team found that among 33 MCI participants with a genetic risk for Alzheimer’s, many had oral microbiomes dominated by Prevotella instead of Neisseria. One species, P. intermedia, strongly
correlated with a higher dementia risk, suggesting it could serve as an early disease marker.
Prevotella bacteria appear to use nitrate for their own purposes, reducing the amount available for nitric oxide production. The researchers believe shifting the balance toward Neisseria while limiting Prevotella could improve nitric oxide levels and benefit brain health. Diets rich in nitrates, such as the Mediterranean diet, are already linked to better cognitive function, but further research is needed to explore the connection between diet, the oral microbiome, and key signaling molecules.
A 2021 study found that older adults with Neisseria-dominant microbiomes, along with the related Haemophilus genus, maintained better attention spans, even when dietary nitrate intake varied. Other studies have associated higher Neisseria levels with younger age, lower BMI, healthier teeth, and non-smoking habits.
“Collectively, these results indicate that a high relative abundance of bacteria in the Neisseria–Haemophilus module is linked to better cognitive outcomes in both individuals with MCI and healthy older adults,” L’Heureux and her colleagues concluded.
Rezvani has made a name for itself with its bold and unapologetically extravagant vehicles, such as the Hercules 6×6 – massive in both size and cost. For 2025, the brand introduces the Vengeance, a custom-built SUV designed to be both luxurious and apocalypse-ready.
The Vengeance is advertised as a fusion of “luxury and military,” and it certainly delivers on that promise. From every angle, it exudes the kind of intense, larger-than-life appeal that survivalists, adventurers, and Mad Max enthusiasts would find thrilling. (I’ll admit, I’m one of them—don’t tell anyone, though. We’re among friends, right?)
The base model, built on GM’s T1 platform—the same chassis used by the Cadillac Escalade— comes equipped with a 6.2L V8 engine that delivers a respectable 420 hp (313 kW) and 460 lb-ft (623 Nm) of torque. Alternatively, you can opt for the diesel version, featuring a Duramax 3.0L DOHC I-6 Turbo-Diesel engine, which generates up to 277 hp (206 kW) and 460 lb-ft (624 Nm) of torque.
Rezvani Vengeance: The SUV that Offers More Than the Usual
Either option gets the job done; this giant weighs in at just 6,200 lb (2,812 kg), a remarkable feat given its impressive dimensions of over 18 feet long, nearly 8 feet wide, and six-and-a-half feet tall (559 cm / 239 cm / 198 cm). For those seeking more power, Rezvani also offers the bulletproof Tank, which boasts
over 1,000 horsepower.
The seven-seat base model comes loaded with the luxury features you’d expect from a high-end SUV, including an ionizing air purifier, a 19-speaker sound system, tri-zone climate control (for when two zones aren’t enough), NFC phone pairing, magnetic ride control, a 10-speed automatic transmission… and of course, automatic seat belt tightening for added safety.
Would you be interested in bulletproof glass and B6-rated armor, capable of stopping 7.62x51mm NATO rounds or a .308 Winchester? How about some Undercarriage Explosive Protection? That might come in handy after a spicy meal. Planning a bit of light ramming? Just check the box for steel “ramming bumpers.” Want run-flat tires and bead locks to go with that?
▶ The Vengeance gives off scary Robocop vibes just sitting there. (Rezvani)
That’ll set you back a cool US$285,000. Not too shabby, especially when you consider a fully loaded 2025 Cadillac Escalade costs $185,688.
However, it’s the options catalog that really makes this stand out. After all, no one buys a “luxury meets military” SUV without actually embracing the “military” aspect. Let’s begin with the exterior, since that’s what everyone will notice as the Vengeance makes its presence known on the road.
But none of those options come with buttons, and let’s be real—we’ll need buttons. So, we should also consider adding extras like smoke screens, thermal night-vision, and explosive device detectors to give us the upper hand. We’ll throw in blinding strobe lights, sirens, and EMP protection (you know, just in case of a nuclear blast). Feeling bold? Let’s add pepper spray dispensers to the side mirrors and even electrify the door handles.
And the pièce de résis-
tance: a custom $2,000 Ferrari logo (or any logo you prefer) that projects onto the ground when the front doors open. Ferrari? Because with a Rezvani Vengeance, you can do whatever you want.
Inside, we’ve got magnetic deadbolts to prevent anyone from prying the doors open, check. You can also opt for reclining “executive seating” complete with all the luxury features you’d expect from the 1%, check. And to top it off, a complimentary bulletproof vest, matching helmet, and military gas mask, also check.
Like many of the newer Escalades, the Vengeance also features Augmented Reality (AR) navigation, allowing the driver to lower below windshield level and still navigate using the dashboard monitor in the event of an incoming RPG.
The interior isn’t just functional; it’s also incredibly luxurious. With premium leather, cutting-edge infotainment, and cruise control, the Vengeance is designed for comfort. Even “The Beast” – the vehicle in the POTUS motorcade –might feel a bit envious, as the Vengeance boasts something The Beast doesn’t: 4-wheel drive and significantly more ground clearance.
For starters, I certainly do. But Rezvani targets the Vengeance to a very specific group: ultra-
high-net-worth individuals, celebrities, and those who require a high level of personal security—think diplomats in dangerous areas where kidnapping is a real threat, or people in Beverly Hills trying to avoid the paparazzi.
Although Rezvani creates a highly specialized product—and the average person would likely never need the Vengeance’s EMP protection or wear the included gas mask (except for an Instagram photo)—there’s no denying that this is one impressive piece of machinery.
Perhaps that’s the bold statement Rezvani owners are aiming for: a status symbol that says, “I probably won’t need it, but I have it just in case.” Fully customized to my preferences, the Rezvani Vengeance comes in at nearly three-quarters of a million dollars. The check is on its way.
New Fusion Record by Surpassing 1,000 Seconds
Scientists have just achieved a new milestone in their efforts to create an ‘artificial Sun’ on Earth. The team behind China’s Experimental Advanced Superconducting Tokamak (EAST) successfully kept their fusion drive running for over 1,000 seconds, with a precise duration of 1,066 seconds, or nearly 18 minutes.
Launched in 2006, EAST is one of several nuclear
fusion reactors being developed to generate nearly endless clean energy, mimicking the way the Sun produces power.
Plasma Physics at the Chinese Academy of Sciences.
Simulating a miniature Sun in a lab is incredibly challenging, which is why achievements like this are so significant.
Maintaining stable, ultra-hot plasma for long durations is essential for EAST’s success, and the new record of 1,066 seconds breaks the previous plasma stability record of 403 seconds.
The breakthrough was accomplished by researchers at the Institute of Plasma Physics (ASIPP) and the Hefei Institutes of Physical Science (HFIPS), both under the Chinese Academy of Sciences (CAS).
“However, a fusion device must operate stably and efficiently for thousands of seconds to enable the self-sustaining plasma circulation, which is essential for the continuous power generation of future fusion plants,” says nuclear physicist Song Yuntao from the Institute of
Equivalent to 140,000 Microwave Ovens Powers 1,066-Second Achievement
Although China hasn’t released many details about the conditions for the 1,066-second achievement, the researchers note that their heating system has recently doubled in power, now capable of generating the equivalent energy of 140,000 microwave ovens running simultaneously.
Since its inception, the EAST team has consistently improved the plasma temperature and stability at the core of the reactor, utilizing high-confinement plasma, a more efficient method for trapping the gas.
Tokamak reactors like EAST use plasma and magnetic fields to create the extreme conditions needed to collide hydrogen atoms at high speeds and intense pressure, releasing massive amounts of energy.
Though we’re still far
from having a fully operational nuclear fusion reactor connected to power grids, each advancement in this technology is promising and adds to the growing evidence that fusion energy could one day be a viable power source.
Looking ahead, work is already progressing on the International Thermonuclear Experimental Reactor (ITER) in southern France, set to be the largest fusion reactor to date and one that could potentially set even more records.
sea surface warming. A study from the University of Reading reveals that the ocean’s surface is now heating more than four times faster than in the late 1980s.
While El Niño and rising CO2 levels were expected contributors, additional factors may be amplifying the trend. Scientists point to increased heat-trapping water vapor from the 2022 Hunga Tonga-Hunga Ha’apai eruption, fewer cooling aerosols due to 2020 shipping regulations, and peak solar activity. Yet, even combined, these factors fail to fully explain the surge in temperatures.
Ocean Warming Accelerates: Sea Surface Temperatures Rising 4.5x Faster Than in the 1980s
▶ Sea surface temperature anomalies for 27 January 2025. The deeper the warm colors, the more anomalously high the sea temperature is. (NOAA)
The sharp rise in global temperatures since 2023 has fueled relentless disasters worldwide, from the still-burning LA fires to the deadly Valencia floods, leaving scientists scrambling for answers.
New ocean data suggests a key culprit: an alarming acceleration in
To investigate further, meteorologist Chris Merchant and his team analyzed satellite records dating back to 1985. They found that in the 1980s, sea surface temperatures rose at about 0.06°C per decade. Today, that rate has jumped to 0.27°C per decade—and it’s accelerating. Although El Niño played a role, the study estimates that nearly half of the excess heat stems from the ocean absorbing energy far faster than expected
over the past decade.
“If the ocean were a bathtub, in the 1980s the hot tap was running slowly, warming the water just a fraction of a degree each decade,” explains Merchant. “Now, the tap is running much faster, and the warming has picked up speed.”
If this trend continues, the next 20 years will bring more sea surface warming than the last 40 combined. Scientists warn this accelerating energy imbalance could devastate marine ecosystems, worsen food insecurity, and intensify health crises.
Policymakers must recognize that past warming trends underestimate the pace of future change, underscoring the urgent need for deep cuts in fossil fuel use. Scientists have long outlined solutions, yet fossil fuel subsidies continue to drive the crisis. Every action to curb emissions now will save lives, no matter where we stand on this dangerous trajectory. strategies.
A phase 3 clinical trial found that adding nivolumab, a targeted immunotherapy drug, to chemotherapy nearly doubled cure rates for patients with the most common type of breast cancer, estrogen receptor-positive (ER+)/ HER2-negative (HER2–). This finding signals a potential shift in treatment
▶
Building on the success of combining immunotherapy with chemotherapy for Hodgkin lymphoma, researchers from Australia’s Peter MacCallum Cancer Center demonstrated its effectiveness for ER+/ HER2– breast cancer, which accounts for 70% of the 2.3 million breast cancer cases diagnosed globally in 2020.
These cancers respond to estrogen, promoting tumor growth, and current treatments include chemotherapy, surgery, or hormone therapy, sometimes paired with targeted drugs.
The CheckMate 7FL trial explored whether nivolumab could improve outcomes for early-stage, high-risk ER+/HER2– patients. Nivolumab blocks the PD-1 receptor on immune T cells, preventing cancer cells from evading detection and enabling T cells to destroy tumors.
Nivolumab Nearly Doubles Pathological Complete Response Rates
In the trial, 510 patients received chemotherapy with either nivolumab or a placebo. Nivolumab-treated patients achieved a pathological complete response (pCR) rate of 24.5%, nearly double the 13.8% seen in the placebo group. Among PD-L1 biomarker-positive patients, pCR rates rose to 44% versus 20% with placebo.
“These patients are likely cured, as no cancer cells were detected in their breast or lymph nodes post-treatment,” said Professor Sherene Loi, the study lead. Longer follow-up will reveal if improved pCR rates translate to better eventfree survival (EFS).
While promising, nivolumab raised safety concerns. Side effects like hair loss, nausea, anemia, and fatigue were common, with serious adverse events, including five deaths, reported in the nivolumab group.
Despite these issues, researchers remain optimistic, calling the findings a milestone in neoadjuvant treatment for ER+/HER2– breast cancer.
By utilizing AI, scientists have engineered proteins that counteract the toxins from cobras and other venomous snakes. This proof-of-concept approach could eventually lead to a new treatment for snakebites. In laboratory tests, the tailored proteins saved the lives of mice exposed to a lethal dose of toxins, as reported by researchers on January 15 in Nature.
“These proteins are truly effective,” says Michael Hust, an antibody researcher at the Technical University of Braunschweig in Germany, who was not involved in the study. “The mice are surviving. This is exactly what we aim for.”
This research builds on the groundbreaking work that earned three scientists the 2024 Nobel Prize in Chemistry. In 2022, medical biotechnologist Timothy Jenkins came across a preprint from David Baker’s lab at the University of Washington, one of the Nobel laureates. The preprint described AI-designed proteins that adhere strongly to specific molecules.
This sparked an idea: could AI design a protein that binds to and neutralizes snake venom toxins?
Jenkins, from the Technical University of Denmark, had spent years trying to create new
therapies for snakebites, which claim around 100,000 lives globally each year. Venomous snake bites can inject a wide range of toxins, including three-finger toxins, which paralyze muscles, stop hearts, and disrupt breathing. While antivenoms exist, Jenkins notes that the technology is outdated. “There’s not much profit in it, so innovation has been limited,” he says. Currently, antivenom production involves milking venom from snakes, a dangerous process, and injecting small amounts of venom into horses or other animals to harvest antibodies. These antibodies, when administered to snakebite victims, neutralize the toxins. However, manufacturing antivenoms is expensive and slow, prompting scientists to explore alternative methods. One promising approach involves screening a large collection of lab-made antibodies to identify those that target specific toxins.
ly and affordably. Jenkins and Baker teamed up to create custom proteins using an AI model called RFdiffusion, a free protein-design tool similar to image-generating AIs. Rather than creating images, RFdiffusion generates protein designs that precisely target molecules scientists wish to neutralize.
Baker’s team had previously trained the AI model using all known protein structures and their amino acid sequences—the molecular building blocks that fold into a protein’s 3D shape. They then computationally deconstructed these shapes, teaching the model how to assemble a complete protein from its parts, much like learning to build a car engine by disassembling one.
Baker and Jenkins used the AI to design proteins that would bind to venom toxins, and then they synthesized these
With AI, scientists can now design toxin-targeting proteins more quick-
custom proteins stopped the toxin from attaching to cells.
The team injected 20 mice with the proteins 15 minutes after or simultaneously with a lethal dose of cobra venom. All the mice survived.
“We were very, very excited about this,” Jenkins says, calling it a clear demonstration of the proteins’ effectiveness. The next step for the team is to develop these proteins into a product for human testing. Researchers will need to ensure that the custom proteins are safe and do not bind unexpectedly to human tissues, according to Hust.
Jenkins acknowledges that this study is just the first step toward neutralizing venom’s harmful effects. “It was very much about proving that this incredibly new technology works,” he says.t
Could Light Therapy Help Alleviate Alzheimer’s Symptoms?
A new study published in PLOS ONE suggests that light therapy may significantly improve sleep quality, strengthen circadian rhythms, and reduce caregiver burden in Alzheimer’s patients. Alzheimer’s not only impairs memory and cognition but also disrupts sleep and triggers behavioral symptoms like agitation, depression, and aggression. Photobiomodulation, a non-drug therapy that stimulates the brain’s sleep-regulating center, has gained interest as a potential solution. However, comprehensive reviews of its effectiveness and safety have been lacking—until now.
Analyzing Light Therapy’s Impact
To assess its benefits, researchers analyzed 15 high-quality randomized controlled trials conducted between 2005 and 2022 across seven countries. These studies, involving 598 participants, provided crucial insights into how light therapy affects Alzheimer’s and dementia patients.
Promising Findings from Meta-Analysis
proteins in the lab. Like a magnetic cover that prevents a key from fitting into a lock, the
light therapy enhanced sleep efficiency, reinforced circadian rhythm stability, and reduced daytime restlessness. It also alleviated depression, decreased agitation, and eased caregiver stress.
While findings are encouraging, the researchers highlight the need for larger studies to further evaluate potential risks and long-term effects. They conclude that light therapy offers a promising, low-risk treatment option for managing Alzheimer’s symptoms.
“Light therapy improves sleep and psycho-behavioral symptoms in Alzheimer’s patients with relatively few side effects, making it a promising therapeutic approach,” the authors state.
Trump is Pulling the U.S. Out of the WHO. Here’s What it Means
nounced his intention to end U.S. support for the World Health Organization (WHO), a global health and humanitarian body dedicated to disease eradication and tracking outbreaks across borders.
On January 20, Trump signed an executive order outlining the U.S. plan to withdraw from the Switzerland-based organization, a process that takes 12 months. His initial attempt to leave the WHO in July 2020 was blocked by President Joe Biden, who reversed the move after taking office in 2021.
The United States was a founding member of the World Health Organization (WHO) in 1948. “For over seven decades, WHO and the USA have saved countless lives,” the organization stated. “Together, we ended smallpox and have brought polio close to eradication.”
U.S. Contribution to WHO and Reasons for Withdrawal
As the largest contributor to the WHO, the
United States donated approximately $1.25 billion between 2022 and 2023. Germany, the
second-largest donor, contributed $856 million during the same period. Trump cited the “unfairly burdensome” financial obligations of the U.S. as a key reason for withdrawing from the organization, along with dissatisfaction with WHO’s leadership during the COVID-19 pandemic.
While this move will reduce U.S. spending, experts warn that it may come at a significant cost. A group of health policy experts noted on January 21 in the BMJ that it would leave the WHO weakened and isolate the U.S. at a time when global health challenges require cooperation. They also emphasized that the decision would “severely diminish American influence and standing in the world.”
To explore the potential impacts of this withdrawal, Science News interviewed Paul Spiegel, director of the Johns Hopkins Center for Humanitarian Health. The interview was edited for length and clarity.
Spiegel: The WHO establishes global health standards and creates international health regulations that require governments worldwide to report certain diseases, including those with epidemic potential. It serves as an early warning system for infectious diseases and facilitates global surveillance and data sharing. The U.S. benefits from the data WHO gathers from various countries.
The WHO also offers vaccinations and provides guidance to governments on noncommunicable diseases, covering areas like tobacco control, cancer screening, and diabetes management. It is a key source of technical expertise for many nations globally.
Additionally, the WHO supports countries during humanitarian crises.
Spiegel: The United States is by far the largest contributor, and it’s unlikely that other countries will be able to fill the gap. This will have a significant impact on the WHO, which will likely have to either close offices or reduce staff.
Spiegel: Certainly, some of the world’s poorest nations, such as many in Africa and parts of the Middle East, will be affected. The WHO will face tough decisions and will need to review its budget to determine where to make cuts.
WHO’s Health Response to Humanitarian Crises at Risk of Cuts, Threatening Millions in Conflict Zones
In places like Ukraine, Sudan, Gaza, and Myanmar, the WHO is coordinating health responses to humanitarian crises, which is extremely costly. I expect this will be one of the areas targeted for cuts due to the high expenses involved. This would have a devastating impact on potentially hundreds of millions of people impacted by conflict and humanitarian emergencies.
Spiegel: I don’t see any advantage for the U.S. in withdrawing. In fact, it ultimately makes Americans less secure from a public health standpoint.
The U.S. relies on the WHO’s work, especially since the Centers for Disease Control and Prevention (CDC) collaborates closely with the organization on global health security. Leaving the WHO puts America in a more vulnerable position, particularly concerning infectious diseases.
WHO’s disease surveillance will be diminished, leading to less information being shared, and it’s uncertain whether the coordination between WHO and the CDC will continue as it did before.
Spiegel: Yes, in numerous studies, the WHO has helped facilitate U.S. collaboration with various ministries of health. The organization is highly respected by health ministries worldwide and plays a key role in networking and coordinating research.
Withdrawing from the WHO could have a negative impact on the research conducted in the U.S.
At the World Health Assembly, the U.S. plays a significant role in numerous decisions, ranging from vaccine procurement to diplomatic matters. By withdrawing, the U.S. will not only be excluded from these discussions but will also create a leadership vacuum, which other countries, like China, will likely attempt to fill.
▶ Salk Institute
If you’re among the 13% of American adults who have used GLP-1 drugs for weight loss, you likely know that along with fat loss comes muscle loss. And if you don’t engage in weightlifting or have conditions that prevent you from starting an exercise regimen, you have limited options to combat this.
However, researchers at the Salk Institute have identified a molecule that could be a game-changer. They discovered that a protein called BCL6 is responsible for maintaining muscle structure, and increasing its levels could prevent muscle tissue from breaking down without hindering weight loss.
Muscle is the most abundant tissue in the human body, so its maintenance is crucial for our health and quality of life, said
Ronald Evans, professor and director of the Gene Expression Laboratory at the Salk Institute.Our study reveals how the body coordinates muscle preservation with energy and nutrition levels. With this new understanding, we can develop treatments for patients losing muscle due to weight loss, aging, or disease.
This discovery extends beyond those taking GLP-1 drugs. Although scientists conducted the research on mice, they are confident they can apply the findings to human physiology.
While studying the mechanisms of fasting, researchers noted that the stomach and brain communicate to stimulate the secretion of a growth hormone targeting muscle tissue. This process reduces BCL6 levels, which weakens and shrinks the muscle’s structure.
When researchers boost-
ed BCL6 levels, muscle tissue became resistant to this process, meaning weight loss would come solely from fat. In mouse experiments, those without the BCL6 boost had 40% less muscle mass compared to the control group and structurally weaker muscles. Conversely, when BCL6 levels were restored, muscle loss and strength depletion were reversed.
Interestingly, in fasting mice, BCL6 levels dropped significantly in as little as one night.
We’re excited to highlight BCL6’s critical role in maintaining muscle mass, said Hunter Wang, lead author of the study and postdoctoral researcher in Evans’ lab. These findings are both surprising and promising, paving the way for new discoveries and therapeutic innovations.
The team believes this discovery could lead to the development of a BCL6 booster to be used alongside GLP-1 drugs, preventing muscle loss. For now, the researchers plan to study the effects of longer fasting periods and their impact on muscle tissue. This type of BCL6 therapy could also benefit broader populations, including older adults and individuals with muscle-impacting conditions such as cancer.
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A UNICEF report shows that climate disasters disrupted education for 242 million students in 2024, making it the most climate-affected year on record. Heatwaves, floods, and cyclones forced school closures worldwide, with South Asia experiencing the worst impact.
Children are highly vulnerable, struggling to learn in extreme heat or when schools are damaged. UNICEF warns that disruptions will increase, calling for urgent investment in climate-resilient education systems to protect children’s futures.
MIT researchers have devised a new method for producing ammonia using Earth’s heat and minerals, eliminating CO2 emissions and external energy needs. Inspired by a hydrogen-rich well in Mali, their process injects nitrogen-enriched water into iron-rich minerals, producing ammonia sustainably. Using olivine and a copper catalyst at 300°C, they achieved 1.8 kg of ammonia per ton of olivine.
This breakthrough offers a globally adaptable solution, though challenges remain in drilling and underground reaction management. With real-world tests planned and a patent secured, this innovation could revolutionize sustainable ammonia production and drive future green energy advancements.
Doomscrolling fuels climate anxiety, making it vital to balance awareness with mental well-being. Instead of disconnecting, individuals can shift to action-focused engagement, reducing distress while staying informed.
Climate Cafe GNV offers a supportive space for discussion, while creators like @relauren and @jess.cliftonn share sustainable solutions. By curating content and engaging with community-driven initiatives, individuals can transform anxiety into meaningful action.
A study from the University of California, Irvine confirms that climate change is altering ocean nutrient cycles. Over 50 years of data reveal a decline in phosphorus in the southern hemisphere, which affects plankton and higher marine life. Surprisingly, nitrate levels remain stable despite predictions of decline. Researchers stress the need for continued data collection to monitor these trends.
Future research will focus on how these changes impact marine ecosystems. Understanding the relationship between nutrient cycles and ecosystem dynamics could provide a valuable tool for tracking ocean health as climate change progresses.
LLMs are central to AI development in the U.S. and Europe, but their limitations raise concerns about overreliance. China takes a broader approach, investing in both LLMs and alternative GAI methods to reduce strategic risk.
China also prioritizes AI safety and value alignment, embedding societal priorities into its development. The report urges the U.S. to diversify AI research and closely monitor China’s advancements to ensure long-term competitiveness in the field.
OpenAI has launched Deep Research, an AI tool that autonomously gathers and synthesizes online information. It analyzes text, images, and PDFs, refining searches to generate detailed reports.
While useful for professionals, Deep Research may struggle with misinformation and unreliable citations. OpenAI acknowledges these risks but emphasizes its economic potential. Available via ChatGPT Pro, it runs on OpenAI’s latest reasoning model, OpenAI o3.
AI, H1Bs, and the Changing Landscape of Tech Employment
Debates on H1Bs and tech jobs shifted to generational inequality but overlooked AI’s impact. AI may boost developer productivity like a standard deviation increase in IQ, making skill concerns less relevant.
With more CS graduates and AI reducing barriers, tech salaries could decline. If AI makes coding accessible, H1Bs may be unnecessary. The author examines data on AI’s job performance impact to understand the evolving job market.
AI
A study published in Nature Medicine found AI-assisted mammogram analysis improved cancer detection by 17.6% without increasing false positives. Conducted on nearly 500,000 women in Germany, the study suggests AI could enhance screening accuracy.
AI’s role in the screening process is still under discussion, but experts like Stefan Bunk propose it could replace one of the initial radiologists, helping streamline the review process.
Morgiane, an opera by Edmond Dédé composed in 1887, has premiered after being locked away for over a century. The opera, based on Ali Baba and the 40 Thieves, was never performed in Dédé’s lifetime but is now being staged by OperaCréole and Opera Lafayette in multiple cities.
Dédé, a composer born in New Orleans, fled to France to escape racial discrimination. His opera reflects the cultural blend of French, Italian, and Southern American traditions, bringing an often-overlooked part of American music history to the forefront.
Viz Media’s Path of the Lightsaber introduces Nioka, a tinkerer who discovers a High Republic-era lightsaber, attracting dangerous attention. As she learns to wield it, her journey unfolds amid new challenges. More details will be revealed at Celebration Japan in April.
Meanwhile, Sanctuary – A Bad Batch Novel releases August 5, 2025. Set after the Pabu episode, it follows Clone Force 99 as they take on risky missions to help rebuild their home. Facing Imperial threats and unexpected dangers, their survival depends on trust and teamwork.
Mona Lisa Gets Her Own Space at the Louvre
The Mona Lisa is being moved to a new room at the Louvre to address overcrowding and allow for a better presentation. This will give other masterpieces in the Salle des Etats, like Titian’s Man with a Glove and Veronese’s The Wedding Feast at Cana, more attention.
Art experts believe this will help visitors focus on these works without the distraction of the Mona Lisa.
Image Credits: Nintendo
Nintendo has announced the Switch 2, with a reveal trailer showcasing its improved design and magnetic Joy-Cons. A special Nintendo Direct on April 2 will reveal more details, and handson events begin April 4 in major cities worldwide.
Expected to launch in mid-2025, the Switch 2 features a larger screen, ergonomic improvements, and upgraded Joy-Cons. Fans can sign up for Experience event tickets via a lottery system.
▶ Credit: AI
The Chinese AI company DeepSeek has made a major impact on the tech industry by launching highly efficient AI models that rival advanced offerings from US firms like OpenAI and Anthropic.
Established in 2023, DeepSeek has reached its milestones using significantly less funding and computing power than its rivals.
Last week, the company unveiled its “reasoning” R1 model, sparking enthusiasm among researchers, surprising investors, and prompting reactions from major AI players. On January 28, DeepSeek took things further by introducing a model capable of processing both images and text.
So, what exactly has DeepSeek accomplished, and how did it achieve it?
In December, DeepSeek introduced its V3 model, a highly capable large
language model that rivals OpenAI’s GPT-4o and Anthropic’s Claude 3.5 in performance.
Like other models, V3 can make mistakes or generate incorrect information, but it excels at tasks such as answering questions, writing essays, and producing computer code. In tests of problem-solving and mathematical reasoning, it has outperformed the average human in some cases.
Training V3 reportedly cost around $5.58 million—significantly less than GPT-4, which required over $100 million to develop.
DeepSeek claims to have trained V3 using around 2,000 specialized H800 GPUs from NVIDIA—far fewer than some competitors, which have reportedly used up to 16,000 of the more powerful H100 chips.
On January 20, the company introduced R1, a “reasoning” model designed to tackle complex
problems step by step. These models excel at tasks requiring contextual understanding and interconnected reasoning, such as reading comprehension and strategic planning.
R1 is an enhanced version of V3, refined through reinforcement learning. Its performance appears comparable to OpenAI’s o1, released last year. DeepSeek also applied the same technique to create “reasoning” versions of smaller open-source models that can run on personal computers.
This release has fueled intense interest in DeepSeek, boosting the popularity of its V3-powered chatbot app and causing a dramatic shake-up in the tech market. Investor reactions have led to a sharp decline in stock prices, with NVIDIA losing approximately $600 billion in market value at the time of writing.
DeepSeek’s key innovation lies in improving efficiency—achieving strong performance with fewer resources. The company has introduced two groundbreaking techniques that could influence AI research more broadly.
The first involves a mathematical concept known as “sparsity.” AI models contain vast numbers of parameters (V3 has about 671 billion), but only a small portion is used for any given input.
Identifying which parameters are necessary is challenging, but DeepSeek developed a novel method to predict and train only the relevant ones, significantly reducing the required training resources.
The second breakthrough relates to how V3 manages data storage in computer memory. DeepSeek has devised an efficient compression technique that makes storing and retrieving essential information faster and more effective.
DeepSeek has released its models and techniques under the open MIT License, allowing anyone to download, modify, and use them freely.
While this move could challenge AI companies reliant on proprietary models for profit, it is a major win for the broader AI research community.
Currently, AI research often demands immense computing power, limiting the ability of university-based researchers and those outside major tech firms to conduct experiments. However, DeepSeek’s efficiency-focused methods could lower these barriers, making experimentation and development more accessible.
For consumers, AI access may also become more affordable. More models could run directly on
personal devices like laptops and smartphones, reducing reliance on cloud-based services with subscription fees. For well-funded research teams, greater efficiency may not be as transformative. It remains to be seen whether DeepSeek’s approach will lead to AI models with superior overall performance or simply ones that require fewer resources to train and run.
revealing that common sleep drugs like Ambien may disrupt it.
The glymphatic system, discovered in mice a decade ago, channels cerebrospinal fluid into the brain to flush out waste, including toxins linked to Alzheimer’s. It also balances water, supports the immune system, and delivers energy. While past studies tied the system’s activity to brain waves during sleep, most relied on anesthetized animals, leaving gaps in understanding its natural function.
Using fiber optic implants, researchers tracked norepinephrine, a neurotransmitter, in
When you sleep and dream, your brain may undergo a “rinse cycle,” clearing out toxic by-products to prepare for the next day. Researchers from the University of Copenhagen have now mapped the flow of neurotransmitters, blood, and cerebrospinal fluid in mice, uncovering how this process works—and
awake and sleeping mice. They found that during non-dreaming sleep, norepinephrine caused rhythmic blood vessel contractions, helping cerebrospinal fluid penetrate the brain. This deep-sleep cleansing was less effective during wakefulness or dreaming.
Zolpidem’s Disruptive
The team also explored how sleep aids like Zolpidem affect the process. They discovered that the drug reduced the rhythmic oscillations, hindering cerebrospinal fluid from fully flushing the brain.
While more research is needed to confirm these findings in humans, the study underscores the importance of deep, natural sleep for brain health. Sleep medications still have their place, but understanding their potential impact could guide future decisions about their use.
New Fusion Milestone with Record-Breaking Thousand-Second Run
mental Advanced Superconducting Tokamak (EAST) reactor in Hefei set a new record by sustaining a fusion reaction for 1,066 seconds. This breakthrough demonstrates significant progress toward fusion as a clean, virtually limitless power source.
Efforts to harness hydrogen fusion, the force behind hydrogen bombs, have been ongoing for decades, driven by scientific curiosity, technical challenges, and Cold War rivalries. Today, with over $7.1 billion in private investment, the goal of achieving commercial fusion energy remains crucial. A single gram of deuterium-tritium fuel can release energy equivalent to 11 tonnes of coal, offering the promise of nearly infinite clean energy.
While fusing hydrogen atoms has been possible in labs for years, practical
▶ The EAST reactor (Credit: Xinhua)
China has achieved a major milestone in the pursuit of practical fusion energy. The Experi-
fusion energy requires extreme conditions: temperatures of 100–150 million °C, pressures of five to 10 atmospheres, and stable plasma for extended durations.
Achieving long-term stability is critical for future fusion plants.
“A device must operate stably and efficiently for thousands of seconds to enable self-sustaining plasma circulation, essential for continuous power generation,” noted Song Yuntao, director of the Institute of Plasma Physics under the Chinese Academy of Sciences.
EAST’s new record builds on its previous achievement of sustaining a 403-second reaction in 2023. This improvement was made possible by upgrades to the experimental system, which doubled the power output while maintaining stability.
Importantly, EAST serves as a stepping stone rather than an endpoint. China is one of seven members of the International Thermonuclear Experimental Reactor (ITER) program, which is constructing the world’s largest tokamak fusion reactor in southern France. Expected to begin operations around 2035, ITER will incorporate findings from EAST as part of China’s nine-percent contribution to the project’s construction and operation.
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Mycology is the branch of biology that studies fungi, including their taxonomy, genetics, ecology, and uses. It covers a wide range of organisms, such as mushrooms, molds, and yeasts. Mycologists explore the role of fungi in ecosystems, their potential in medicine (e.g., antibiotics like penicillin), and their impact on agriculture, both as pathogens and beneficial organisms.
Country: Angola
Term of the Week
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The average color of the universe, determined by astronomers to be a pale beige.
The Ford GT90, Dodge Copperhead, and Jaguar XK180 are just a few 90s concept cars that missed production despite their innovative designs and powerful engines. BMW’s Nazca M12 and Audi’s Quattro Spyder also showed promise but were never built. Other cool concepts like the Plymouth Pronto Spyder and Nissan Trailrunner highlighted the era’s creativity, while Mazda’s RX01 hinted at a lighter, fun rotary car that never came to be.
Alpine A310 Set to Challenge the Porsche 911 in 2028
Alpine is set to launch the A310 in 2028, expanding beyond the twoseat A110. Built on a lightweight electric platform, it aims to rival the Porsche 911.
CEO Philippe Krief brings expertise from Ferrari and Alfa Romeo, ensuring high performance. The A310’s design may draw from the A390 concept, blending futuristic and retro elements. Unlike some EVs, Alpine will forgo artificial engine sounds, focusing on authentic driving dynamics.
Ford unveiled a Mach-E prototype for NASCAR, featuring a carbon-fiber chassis and NASCAR components like suspension, steering, and brakes. The model resembles the standard Mach-E but is designed for racing.
The prototype hints at a potential electric future for NASCAR, with a three-motor system and a 78kWh battery. Despite traditional fans’ resistance, electric series might emerge, with the Mach-E driving forward electrification in motorsports.
The 2026 Toyota MR2 is expected to be based on the FT-Se concept, with a rumored turbocharged 2.0-liter engine producing 400 hp for street versions and 600 hp for track-only models. A mid-engine design and a starting price around $70,000 are speculated.
Though Toyota has not confirmed details, many are excited about its potential to offer cutting-edge performance and accessible technology, making it a top contender in the sports car market.
Pi Day:
Celebration of the Infinite Constant
Casual Pi Day on July 22 is a fun opportunity to appreciate pi (π), the irrational number that represents the ratio of a circle’s circumference to its diameter. Unlike Pi Day on March 14, this day allows math lovers to dive into pi’s fascinating properties.
Pi has inspired mathematicians for centuries, with its infinite nature influencing not just math but fields like physics and art. People celebrate Casual Pi Day through activities like memorizing pi’s digits, pie-eating, and participating in math challenges.
A groundbreaking study delves into the mathematical principles behind creativity, focusing on the process of discovering new elements and forming novel combinations. The research introduced a new mathematical model, ERRWT, to simulate how individuals generate ideas. The study applied this model to music, literature, and scientific publications, revealing that creativity often stems from recombination rather than the creation of entirely new elements.
PDEs model fundamental physical laws, from heat distribution to electromagnetic fields. Prof. Ugur Abdulla’s work at OIST has advanced this field, notably solving Kolmogorov’s 1928 problem by linking spacetime geometry to singularities in diffusion processes. His insights have influenced multiple disciplines.
His team is also pioneering early cancer detection using electrical impedance tomography and PDE-based control theory. By analyzing conductivity variations, this method provides high-resolution imaging. Computational tests show promising results, with plans to collaborate with medical institutions for real-world validation.
Okinawa Institute of Science and Technology Graduate University
The Limits of Mathematical Knowledge: Hilbert’s 10th Problem and the Quest for Decidability
Hilbert’s dream of complete mathematics met an insurmountable limit when Gödel and Turing showed that some problems cannot be solved. One of Hilbert’s key problems, the 10th, concerning Diophantine equations, was resolved by Yuri Matiyasevich in 1970, proving that no general algorithm could determine if an equation had integer solutions. This issue remains unresolved even for more complex number systems.
Recent research by Peter Koymans and Carlo Pagano extended this conclusion, proving that the undecidability of Hilbert’s 10th problem holds for a wide range of number systems beyond integers. By using elliptic curves, they showed that no algorithm can solve Diophantine equations for all rings of integers, reinforcing the inherent limits of mathematics.
Efficient Solar Energy Conversion Through Quantum Mechanics
A new study reveals how quantum mechanics plays a crucial role in photosynthesis, helping plants efficiently convert solar energy. This process involves the superposition of excited states in chlorophyll molecules, enabling loss-free energy transfer.
By studying chlorophyll’s behavior in different light regions, researchers are gaining insights into how quantum effects can be applied to artificial photosynthesis systems, potentially revolutionizing solar energy use for electricity and photochemistry.
KIT has launched a fiber optic test facility to advance quantum key distribution and establish a quantum network. The project employs ultra-coherent lasers to generate secure keys based on physical laws, offering stronger encryption against quantum threats.
The facility supports research into quantum memories and entanglement, essential for building a quantum internet. As part of major German quantum initiatives, the project contributes to developing high-performance quantum communication and computing systems.
Glass is neither fully solid nor liquid, forming an amorphous structure that allows light to pass through with minimal scattering. Unlike most materials, its electrons do not absorb visible light photons, preventing reflection or absorption. This makes glass transparent while still blocking some UV light.
Quantum mechanics defies classical physics, as seen in entanglement, where one particle’s state instantly influences another, violating locality. The GHZ paradox proves quantum theory’s incompatibility with local realism, producing mathematical contradictions.
A new study created photons existing in 37 dimensions, exposing unprecedented quantum nonclassicality. This discovery could unlock new technological and theoretical breakthroughs, revealing just how much remains hidden beneath the quantum surface.
COPD remains underdiagnosed, but incorporating a polygenic risk score (PRS) into screening improves detection. When added to a case-finding questionnaire, PRS enhances the identification of undiagnosed cases, guiding targeted spirometry testing. Further research aims to refine PRS accuracy, particularly for non-European populations. By integrating genetic insights with screening tools, early COPD detection could become more efficient, leading to better patient outcomes.
RVC research has linked over 100 genes to bone fracture risk in Thoroughbreds, shedding light on genetic factors influencing susceptibility. A polygenic risk score helped identify key genes affecting bone integrity, including collagen type III.
Future research aims to validate these findings and refine genetic risk assessments. Understanding how gene expression alters bone structure could lead to better preventive strategies, helping veterinarians manage fracture risk in racehorses more effectively.
Metabolite Quantification Through DNA Sequencing: The smol-seq Approach
Smol-seq is a method that combines structure-switching aptamers with DNA sequencing to quantify metabolites. By binding specific targets, these aptamers release barcoded DNA sequences, which can be sequenced to measure metabolite levels in complex samples.
This approach has shown high specificity and the ability to multiplex, enabling the detection of multiple metabolites simultaneously. While it faces challenges with very high concentrations, it holds promise for more efficient and scalable metabolomics analyses.
Key Takeaways from the 43rd Annual J.P. Morgan Healthcare Conference
The 43rd Annual J.P. Morgan Healthcare Conference highlighted a surge in M&A activity, including a $14.6 billion acquisition in central nervous system therapeutics. Private biotech financing is expected to stay strong, focusing on companies with solid management and validated assets. China’s biotech industry is now a major player, contributing significantly to global drug development.
Discussions on FDA regulation, drug pricing, and commercialization strategies were prominent, while AI’s future impact on drug design and healthcare remains debated.
Akshay Kumar’s 4 Tips for Fighting Obesity
Akshay Kumar stresses the importance of sleep, fresh air, and natural oils for a healthy lifestyle. He recommends using desi ghee instead of processed foods, spending time outdoors, and following a regular exercise routine.
According to him, movement is key to boosting metabolism and achieving health goals.
Scott James Bailey, a coach known for his “Daily Mobility Techniques for Stiff People,” recommends shoulder adductions to help with shoulder pain. Performed on a cable machine, this exercise strengthens the rotator cuff and muscles like the pectoralis major and latissimus dorsi, improving mobility and preventing dislocations. Bailey says it can also enhance exercises like pullups and rows.
Purple shampoos are essential for gray hair as they neutralize yellow or brassy tones. Top recommendations include Oribe Silverati for brightening and environmental protection, Amika Bust Your Brass for hydration and repair, and Better Not Younger Silver Lining for volumizing and eliminating brassiness.
Hyaluronic acid hydrates the skin, while retinol boosts cell turnover to reduce wrinkles. Vitamin C brightens, and niacinamide improves elasticity and reduces redness. Exfoliating acids like glycolic and lactic acid enhance texture, while peptides and ceramides firm and protect the skin.
Azelaic acid treats acne and rosacea, and bakuchiol offers anti-aging benefits without irritation. Green tea extract protects from damage, and Cica helps heal and soothe sensitive skin. Lastly, kojic acid brightens and evens skin tone. These ingredients can make a noticeable difference in your skincare routine.
Traffic delays contribute to increased fast food visits, as drivers opt for convenience rather than cooking or grocery shopping. In Los Angeles, a 1% increase in fast food visits occurred due to unexpected delays, highlighting how time constraints affect food choices.
This pattern, particularly during evening rush hours, suggests that improving infrastructure and reducing congestion could help mitigate unhealthy eating habits.
The DO-HEALTH study found that omega-3s, vitamin D, and strength training slow biological aging. Using epigenetic clocks, researchers showed that omega-3s alone delayed aging by up to four months, with the combination proving even more effective.
While the study faced limitations, including its Swiss-only sample, future analyses will expand to other countries. These results support integrating omega-3s, vitamin D, and strength training into aging interventions, potentially improving health and longevity.
Apples are packed with fiber, potassium, and phytochemicals that benefit heart health, dental care, weight management, and gut health. Pectin in apples helps lower LDL cholesterol, while polyphenols support heart health. Apples also aid in managing blood pressure and reducing dental plaque.
Eating an apple before meals can reduce calorie intake, and the fiber feeds healthy gut bacteria, promoting a balanced microbiome. These benefits make apples a great addition to a healthy diet.
The Slow Carb Diet, created by Timothy Ferriss, promotes weight loss through five rules focusing on high-protein foods, vegetables, and legumes, while eliminating carbs, fruits, and dairy. It encourages a cheat day once a week.
The diet’s simplicity may help with cravings and overeating, but its restrictive nature could eliminate important nutrients. Supplements may fill gaps, but they can’t fully replace whole foods, raising concerns about long-term health. While the diet may promote short-term weight loss, its overall sustainability is uncertain.
A study presented at the 2025 International Stroke Conference found that combining higher-intensity walking with standard therapy improved mobility and quality of life in stroke survivors. Participants in the new protocol showed a 43.6-meter improvement on the six-minute walk test and better mobility and balance compared to the usual care group.
The study demonstrated that structured, progressively intense exercise during early stroke recovery can enhance neuroplasticity and reduce disability.
Quentin Lake’s Upper-Body Push-Pull Workout: A Detailed Overview
Quentin Lake’s workout focuses on eccentric exercises, strength, and functionality. It includes push and pull exercises like incline dumbbell bench presses, triceps pushdowns, and cable rows.
The workout emphasizes core stability and muscle mass with movements like bicep curls to overhead presses and farmers walks. It’s designed to improve on-field performance and overall strength, while maintaining variety for the body to adapt.
Research shows that physical activity before a cancer diagnosis can reduce disease progression and mortality. Even modest activity provides significant benefits, with lower rates of progression and death for those who were active before their diagnosis.
Participants in the study who engaged in moderate to high levels of activity had 27% lower odds of progression and 47% lower odds of death. These findings suggest that promoting physical activity may yield important benefits for cancer management and prevention.
Project Rally, a pickleball program designed for cancer survivors, has successfully increased physical activity and social support. A pilot study found that participants improved their endurance and strength while fostering new connections. Cancer survivors increased weekly strenuous activity by over 80 minutes, with high program retention and adherence rates.
Led by Moffitt Cancer Center, the study highlights how community-based programs can enhance survivorship care.
A study shows that women who experience menopause after 55 have healthier blood vessels and lower heart disease risk. The late-onset group exhibited 44% better vascular function than those with earlier menopause, with improved mitochondrial function and favorable lipid levels playing a key role.
The researchers aim to further explore how early-onset menopause impacts heart health and whether mitochondrial-targeting supplements, like MitoQ, could reduce heart disease risk in women. They hope to raise awareness of menopause age as an important health factor.
Actress Andie MacDowell recently shared her struggle with piriformis syndrome (PS), a painful condition affecting the sciatic nerve. PS occurs when the piriformis muscle, located in the buttocks, spasms and irritates the sciatic nerve, causing sharp pain, numbness or tingling down the leg. Women are more prone to PS due to anatomical and hormonal factors.
Treatment includes physical therapy, stretching, posture adjustments and anti-inflammatory medications. In severe cases, injections or surgery may be necessary. Strengthening the core and hips, along with lifestyle changes, can help prevent recurrence. Raising awareness about PS is crucial, especially for women who are disproportionately affected.
A study in JAMA Network Open found that nearly 50% of women who used antidepressants before conception discontinued them during pregnancy without substituting psychotherapy. Researchers analyzed data from 385,731 women and observed a 48.8% drop in antidepressant prescriptions, with no corresponding increase in psychotherapy. Spousal antidepressant use remained stable, suggesting the change was specific to pregnancy.
Image Credits: kjpargeter on Freepik Heart disease is the top cause of death for women, yet many are unaware of its impact. Experts cite misdiagnosis and insufficient education as key factors.
Dr. Merz highlights that one in two women will be affected by cardiovascular disease, and one in four will die from it. Simple lifestyle changes, such as not smoking, eating healthy, and staying active, can help prevent heart disease. Improving doctor training is also crucial for better diagnosis and treatment.
The no-days-off running trend popularized on social media promotes extreme commitment but often overlooks the importance of rest. Ignoring recovery can lead to injury, burnout, and stalled progress. “Social media glorifies streaks, making rest seem weak,” says Rob Dixon, a performance physiologist. A study in JOSPT Open found 72% of runners suffered overuse injuries due to excessive training.
Rest is essential for growth. At least one rest day per week helps muscles rebuild and prevents burnout. Active recovery—light movement, stretching, or yoga— keeps the body primed without excessive strain. “Adapting your schedule for recovery prevents setbacks,” Dixon advises.
Erectile dysfunction (ED) affects millions globally, with sildenafil (Viagra) and tadalafil being common treatments. These drugs enhance erections by inhibiting PDE5, prolonging cGMP activity. Effectiveness depends on proper use—taking the medication 3060 minutes before sex, avoiding fatty meals, and considering dose adjustments. Persistence matters, as success rates increase with repeated use.
Generally safe, ED drugs should be avoided by men taking nitrates. Side effects include headaches and flushing, with rare cases of vision issues.
and Men’s Heart Health: Do Supplements Work?
Omega-3 fatty acids play a crucial role in heart health, but while omega-3-rich foods are beneficial, supplements remain controversial. Dr. Manoj Vithlani explains that EPA and DHA from fish are particularly heart-protective, while ALA from plants also contributes. Research suggests omega-3s lower inflammation and triglycerides, but supplement effectiveness varies due to product quality and individual health differences.
Although supplements provide a convenient alternative, they are not a substitute for a healthy lifestyle.
The no-days-off running streak trend, promoted online, can push athletes to ignore rest, leading to injury and burnout. Performance physiologist Rob Dixon warns that glorifying streaks downplays recovery’s role, while physical therapist Zac Marion highlights studies linking rapid mileage increases to injuries. Success isn’t about running daily—it’s about sustainable training.
Rest and recovery are essential for progress. Scheduling at least one rest day per week, using active recovery like stretching or light swimming, and adapting workouts based on fatigue prevent setbacks. A flexible training plan ensures steady improvement while reducing injury risks, making rest a crucial part of any runner’s routine.
Lake Natron in Tanzania is so alkaline that it can preserve dead animals, giving them a stone-like appearance! The lake’s high levels of sodium carbonate and extreme pH (up to 10.5) cause the bodies of animals that perish in or near the lake to become calcified, almost like natural mummies. Some even look as if they’ve been turned to stone, creating a haunting yet fascinating spectacle!
January 30:
1883: James Ritty and John Birch received a patent for the cash register, revolutionizing transaction recording in businesses.
1982: The first computer virus, known as the “Elk Cloner,” was discovered in the wild. It was written by 15-year-old Rich Skrenta and targeted Apple II computers via floppy disk.
1991: John Bardeen, American physicist and co-inventor of the transistor, passed away. He is notable for being a two-time Nobel Prize laureate in Physics.
January 31:
1851: Gail Borden announced his invention of evaporated milk, which became a significant advancement in food preservation and nutrition.
1893: The Coca-Cola trademark for “nutrient or tonic beverages” was registered, marking a milestone in the branding of one of the world’s most famous beverages.
February 1:
1957: The first nuclear-powered submarine, the USS Nautilus (SSN-571), logged 60,000 nautical miles, matching the endur-
ance of the fictional Nautilus described in Jules Verne’s 1870 novel “Twenty Thousand Leagues Under the Seas.”
February 2:
1935: Leonarde Keeler conducted the first polygraph test on two criminals in Portage, Wisconsin, marking a significant development in forensic science.
February 3:
1966: The Soviet Union’s Luna 9 spacecraft achieved the first soft landing on the Moon, providing panoramic images of the lunar surface.
February 4:
2004: Mark Zuckerberg launched “The Facebook” from his Harvard dormitory, which would later become the world’s largest social networking platform.
February 5:
1872: Birth of Lafayette Benedict Mendel, an American biochemist whose research on vitamins and proteins helped establish modern concepts of nutrition.
1936: Radium E became the first radioactive element to be synthesized, marking a milestone in nuclear chemistry.
A study from the University of Jyväskylä found that a diet high in red meat, fast food, and sugary drinks accelerates biological aging, even in young adults. Biological aging, which may differ from chronological age, is measured using epigenetic clocks. Diets rich in vegetables and fruits were linked to slower aging.
The study, involving twins aged 20–25, suggests that genetics play a key role in diet-related aging differences. However, diet remained independently associated with aging even after accounting for lifestyle factors. Researchers emphasize that a balanced diet can benefit everyone, regardless of genetic background.
Selenoproteins play a vital antioxidant role, neutralizing ROS and lipid peroxides that accumulate with age, especially in HSCs. Disrupting selenoprotein production in a mouse model impaired HSC self-renewal and B cell maturation, similar to what is seen in aging diseases.
Vitamin E supplementation helped protect against these effects, suggesting that improving selenoprotein production could support healthy aging and potentially fight age-related diseases.
WSU researchers created genetically engineered HuT mice with human-like short telomeres to study aging and cellular health. These mice allow for more accurate research on cancer, lifespan, and age-related diseases.
The model offers potential for anti-aging treatments and cancer therapies by targeting telomerase. The HuT mice will also be used to explore how sleep deprivation and other stresses affect aging and telomere regulation.
Image Credits: Pixabay
Mental Health Tied to Resilience in Older Women After Hip Fracture
Research from the Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research reveals that better mental health and fewer depressive symptoms are linked to greater psychological resilience in older adults recovering from hip fractures. The study, involving 129 women, highlights the importance of integrating mental health support into rehabilitation programs to maximize recovery potential.
Hip fractures are a significant health issue, with over 300,000 emergency visits annually.
Women Talk More Than Men? Age May Matter.
A new study challenges the stereotype that women are more talkative than men, finding they speak more only during early and middle adulthood (ages 25-65), averaging 3,000 more words daily. Researchers analyzed 630,000 recordings from 2,197 participants across four countries, revealing no significant gender differences in other age groups.
c2c Trenitalia celebrates research showing 98% of UK commuters listen to music during train journeys to boost mood and mental wellbeing. Popular tracks like *Eye of the Tiger* and *Happy* help passengers prepare for their day, with 57% relying on their commute to improve mental health.
c2c’s 93.5% on-time arrival rate in 2024 exceeds the national average, ensuring a reliable journey.
The 54-minute trip from Southend Central to London Fenchurch Street offers ‘me time’ for 15 songs, enhancing the commute
In *Liberal Bullies*, Luke Conway uses personality psychology to analyze authoritarianism, identifying traits like cognitive rigidity, intellectual apathy, and intolerance for ambiguity. These traits, found across the political spectrum, lead to polarized thinking, double standards, and a rejection of opposing views as misinformation.
Conway argues that combating authoritarianism requires addressing these traits through education and principled resistance. He warns against adopting authoritarian tactics, emphasizing the need for intellectual rigor and tolerance to preserve a free society.
The study also found a decline in daily word counts, dropping from 16,000 to 13,000 between 2005 and 2018, likely due to increased digital communication. Researchers suggest child-rearing roles may explain the gender gap and emphasize the need for further research on socializing’s health impacts.
chological Readiness Post-Concussion
This year’s Super Bowl sees the Kansas City Chiefs aiming for a historic three-peat against the Philadelphia Eagles. As football seasons lengthen and high-contact sports grow, concussions remain a significant concern. Reid Davis, a Michigan State University doctoral student, studies the psychological readiness of athletes returning to play post-concussion, debunking misconceptions like uniform recovery responses and universal return protocols.
Concussions vary by type and individual, with symptoms like headaches or balance issues signaling unreadiness.
Images Credits: Bournemouth University
The research team from Trinity College Dublin uncovered that Iron Age Dorset practiced matrilocality, where men joined their wives’ communities upon marriage. Genetic analysis of over 50 ancient genomes revealed that the society was structured around matrilineal descent.
This discovery, published in Nature, highlights a pattern of female empowerment in Iron Age Britain. It also shows that this practice was widespread, with similar patterns observed across other Iron Age cemeteries in Britain.
The Cochno Stone, a 5000-yearold Neolithic artifact near Glasgow, Scotland, is renowned for its intricate cup-and-ring markings. Discovered in 1887, it was buried in 1965 to protect it from vandalism and later unearthed in 2016 for 3D imaging by archaeologist Kenneth Brophy and the Factum Foundation.
Despite its cultural significance, the stone’s meaning remains a mystery. After being studied and reburied to preserve it, researchers continue to analyze a digital facsimile, hoping to unlock its ancient secrets while safeguarding the original for future generations.
Credits: Wikimedia Common_The Urban Prehistorian via grunge.com
Laser Tech Reveals Tattoos on 1,200-Year-Old Mummies
Tattoos, though perceived as modern, have ancient roots. Researchers recently used laser-stimulated fluorescence (LSF) to uncover intricate tattoos on Peruvian mummies from the Chancay civilization (900–1533 CE). The technique revealed geometric and animal designs, reflecting the Chancay’s artistic mastery seen in their pottery and textiles.
Image Credits: Michael Pittman and Thomas G Kaye
4,500-Year-Old Warrior Graves Unearthed in Germany, Arm Guard Intact
Archaeologists discovered a 4,500-year-old Bell Beaker culture cemetery near Förderstedt, Germany, during power line construction. The site includes ten graves, with three well-preserved burials containing grave goods like a bellshaped vessel, a stone arm guard, and arrowheads.
The graves were protected by loess clay, ensuring exceptional bone preservation. Excavation leader Christian Lau noted the burial pit was dug through upper soil layers and filled with loess clay. The findings, part of the SuedOstLink power line project, will undergo further laboratory analysis.
Image Credits: Klaus-Dietmar Gabbert_dpa
Image Credits: Danielle from Pixabay
We are in a golden age of space exploration, with tools like the James Webb Telescope and gravitational wave detectors uncovering cosmic secrets. Missions to asteroids, the moon, and Mars aim to answer whether life exists beyond Earth.
Life’s definition remains elusive, but its complexity on Earth relies on DNA, RNA, and proteins. Silicon-based life is a theoretical alternative. The origins of life may involve extraterrestrial delivery or geochemical processes
Credits:
China’s space agency demonstrated artificial photosynthesis aboard the Tiangong space station, producing ethylene and oxygen from carbon dioxide, water, and electricity. This process is more energy-efficient than the ISS’s electrolysis method.
China’s future space missions may utilize semiconductor catalysts for oxygen production and fuel synthesis, depending on the process’s effectiveness. The results could revolutionize long-term space travel by reducing reliance on replenishment missions.
Image Credits: NASA_JPL-Caltech_University of Arizona
NASA’s InSight: Meteoroid Marsquakes Reach Deeper Than Expected
Meteoroid impacts on Mars generate seismic signals that penetrate deeper than previously thought, as revealed by NASA’s InSight lander and Mars Reconnaissance Orbiter. A 71-foot crater in Cerberus Fossae, detected using AI, showed seismic waves traveling through Mars’ mantle, challenging existing models of the planet’s crust.
AI tools have revolutionized planetary science, enabling rapid analysis of thousands of images to identify craters and other features.
The European Space Agency (ESA) has partnered with Thales Alenia Space to develop the Argonaut Lunar Descent Element, its first lunar lander. Argonaut will support international Moon exploration, delivering infrastructure, resources, and scientific instruments from the next decade.
Designed for five-year lunar survival, Argonaut integrates with ESA’s Lunar Link and Moonlight systems. It contributes to NASA’s Artemis programme and commercial lunar services, advancing sustainable human presence on the Moon. Thales Alenia Space leads the European consortium, targeting the first operational mission by 2031.
Image Credits: European Space Agency
For decades, physicists have been on an epic quest: to unify Einstein’s General Relativity with Quantum Mechanics. It’s a bit like trying to mix oil and water, but in this case, the oil is the elegant, smooth curvature of spacetime, and the water is the jittery, unpredictable chaos of the quantum world. Both theories work astoundingly well in their respective domains, but when they meet—boom!—they throw mathematical tantrums that have left even the brightest minds scratching their heads.
The Clash of Titans
General Relativity, Einstein’s masterpiece, describes how massive objects warp spacetime, creating what we experience as gravity. It has successfully predicted everything from black holes to the bending of light by distant galaxies. Quantum Mechanics, on the other hand, deals with the bizarre behavior of subatomic particles, where things can exist in multiple states at once, and particles can pop in and out of existence as if the universe were running a never-ending magic show.
The problem? When we try to apply quantum principles to gravity, the equations produce ab-
surd infinities, breaking our beautiful mathematical framework. It’s as if the laws of physics suddenly decided to throw a wild, rule-breaking party.
The Search for a Grand Theory
Physicists have proposed several ideas to bridge the gap. One of the most famous contenders is String Theory, which suggests that everything is made up of tiny, vibrating strings instead of point-like particles. This approach smooths out many of the mathematical conflicts, but it demands extra dimensions of space—up to eleven! So, either we’re all living in a cosmic illusion, or we just haven’t figured out how to see these extra dimensions yet.
Another candidate is Loop Quantum Gravity, which attempts to quantize spacetime itself, breaking it into tiny, discrete loops. Think of it as turning the smooth fabric of spacetime into a cosmic Lego set. While promising, it still struggles to fully integrate with the rest of quantum field theory.
The Biggest Surprises So Far
One of the strangest implications of these efforts is that space and time might not be fundamental. Instead, they could emerge from deeper quantum interactions, much like temperature emerges from the collective motion of atoms. This means that asking
what happened before the Big Bang could be as meaningless as asking what’s north of the North Pole.
Then there’s the infamous Black Hole Information Paradox. According to General Relativity, anything that falls into a black hole is lost forever. But Quantum Mechanics insists that information can never be destroyed. Recent theories suggest that black holes might be like holograms, encoding all the information on their event horizons, much like a cosmic USB drive. Who knew black holes could be so organized?
What’s Next?
Despite the challenges, physicists remain optimistic. Advances in quantum computing, experiments with high-en-
ergy particle collisions, and deeper explorations into black hole physics might one day lead to a breakthrough. Some even speculate that gravity might not be a fundamental force at all but an emergent property of the quantum world. Until then, we live in a universe governed by two brilliant yet conflicting theories. It’s a bit like having two favorite songs that don’t quite harmonize—both are beautiful, but something feels off when played together. The search for unification continues, and with it, the hope that we’ll one day understand the true nature of reality. And if we don’t? Well, at least the universe keeps us entertained with its mind-bending mysteries.
Discover cutting-edge research and innovation at the Royal Society's unmissable Summer Science Exhibition, 1-6 July 2025. This free event will offer an interactive experience, open to everyone with a curious mind.
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A Beijing shopping mall hosted an AI-themed temple fair during Lunar New Year, featuring humanoid robots like Xiao Xin, which interacted with visitors and showcased lifelike expressions. The event blended tradition with technology, including robotic musicians and calligraphy-writing arms, highlighting China’s push for AI innovation.
Attendees like Sophia Wu and Bai Song expressed optimism about AI’s potential, despite technical challenges seen in exhibits like robotic koi fish and football players. The fair underscored China’s ambition to lead in advanced technologies while celebrating cultural heritage.
Image Credits: Xu et al
Researchers at the University of Michigan developed CoNav, a smart wheelchair combining user control with autonomous navigation. Powered by a Robot Operating System (ROS) and model predictive control (MPC), it uses sensors like LiDAR and cameras to detect obstacles and plan efficient paths. CoNav adapts to user input, reducing effort and enhancing safety.
Tested in real-world scenarios, CoNav outperformed traditional manual and autonomous wheelchairs in efficiency and user satisfaction. Future improvements include multimodal inputs and socially aware navigation for crowded environments.
Helping AIs Understand the World Through Robotics
Large language models like ChatGPT lack true understanding, processing data without real-world experience. Researchers at the Okinawa Institute of Science and Technology developed a brain-inspired AI model using neural networks. Trained in a robot with a simple arm and camera, it learned to manipulate colored blocks based on commands, demonstrating compositionality—generalizing knowledge to new tasks.
Challenges include limited workspace and vocabulary, requiring 80% of noun-verb combinations for effective generalization. The team believes advanced GPUs could overcome these issues, aiming to scale the system for real-world applications using humanoid robots.
Quantum mechanics principles like multi-value logic are being applied to solve challenges in swarm-based robotics, enabling decision-making in multi-robot systems.
The article also highlights the use of sonification, which adds a sensory dimension to data, helping users better understand swarm dynamics in robotic applications.
Parenting practices, such as warmth and autonomy support, positively influence adolescents’ digital citizenship behaviors, while structure provision shows no significant link. Adolescents’ positive appraisal of parenting and media disclosure mediate these relationships, highlighting the importance of perceived fairness and trust in fostering responsible online behavior.
Image Credits: nature.com
Waited until the 30s to have kids. Now they’ve hit an unexpected snag
Viviana, like many millennial women, delayed motherhood to prioritize her career, fearing professional repercussions. At 36, she had her daughter, Amelia, but moving to New York in 2023 forced her to quit her job to focus on parenting.
Rising childcare costs and demanding careers push women to wait until their 30s to start families. Many, like Anastasia Dedik and Anita, return to work quickly after childbirth, sacrificing personal needs. Employers often lack support for working mothers, highlighting the need for better parental leave and flexible work policies. Balancing career and family remains a significant challenge for millennial women.
Raising Emotionally Intelligent Kids: A Simple Approach
Gentle parenting isn’t about enabling children but validating their emotions while addressing negative behavior. Fleck emphasizes understanding feelings and guiding healthier reactions to foster emotional intelligence.
Dr. Vicky Bouche recommends active listening, acknowledging emotions, and offering support tailored to each child. This approach, though requiring patience and adaptability, helps raise emotionally intelligent kids.
Cradleboard
The Dakobinaawaswaan exhibition at Thunder Bay’s Nor’Wester Hotel showcases over 250 cradleboards (tikinagan), collected by Shirley Stevens and the Cradle Keepers Collective. These carriers, made from materials like birch bark and beads, symbolize love, protection, and cultural resilience. The exhibit highlights the importance of Indigenous family life and traditions, countering colonial narratives.
Buffett’s Berkshire Hathaway continues adjusting its stock holdings, including reducing Apple and Bank of America stakes while increasing investments in SiriusXM and Occidental Petroleum.
Buffett remains committed to a long-term strategy, focusing on quality stocks with solid returns, like Apple and Coca-Cola, and has seen his portfolio outperform the S&P 500 with consistent gains over decades.
Gold investing has gained popularity recently, as rising inflation and geopolitical tensions have driven prices up. While traditionally viewed as a long-term strategy, gold’s current price volatility has created short-term opportunities. Investment professionals agree that both short- and long-term strategies can work, depending on one’s goals and risk tolerance.
Short-term strategies, such as gold ETFs, offer quick entry and liquidity but come with risks like price slippage and tax liabilities. Long-term strategies align with gold’s historical role as a hedge against inflation and market instability, though they involve storage fees and limited growth. Choosing the right strategy should depend on one’s financial situation and risk appetite.
Financial Health: How to Measure and Improve It
Measuring financial health involves assessing control over your finances, managing unexpected expenses, and securing your future. Conduct an annual checkup, including reviewing your goals, budget, savings, and debt.
Meta Joins Databricks in $10 Billion Funding Round
Meta has joined Databricks’ $10 billion Series J funding round, which has increased the company’s valuation to $62 billion. Databricks provides a platform for building AI applications using complex data and is seeing substantial growth as AI adoption rises.
The investment deepens the collaboration between Databricks and Meta’s Llama team, with thousands of enterprise customers already using Llama on the platform. This partnership, along with the support from major financial institutions, positions Databricks to continue its expansion in the AI sector.
Images Credits: REUTERS_Dado Ruvic_ Illustration_File Photo
Retiring early can have severe consequences, both for health and financial security. Studies show that stepping away from work can trigger health problems like heart disease and stroke, and cause a loss of social connections, particularly in African cultures where work is vital to community identity.
Financially, early retirees often face reduced pension benefits and increased living costs. Moreover, early retirement strains the economy, leading to workforce shortages and greater dependency on younger workers. A more balanced approach, like phased retirement, may be the key to maintaining financial and social well-being in later years.
As the cost of living continues to rise, retirees are seeking more affordable places to live. GOBankingRates identified U.S. cities with low living costs and large retiree populations. Cities in Florida, Arizona, and Arkansas, like Sun City Center, Tonto Basin, and Fairfield Bay, offer affordable housing and annual living costs, often under $50,000.
These cities provide retirees with vibrant communities, ensuring social interaction while keeping living expenses low. With housing values well below the national average, these cities are great options for retirees on fixed incomes.
Land lease communities are becoming an attractive option for retirees seeking low-maintenance, sustainable living with financial clarity. These communities, such as Ingenia’s Beveridge, offer homes with solar panels and advanced insulation that save over $2,000 annually on energy bills. Residents pay a weekly site fee and retain 100% of any capital gains, providing financial security.
Ensuring your money lasts throughout retirement requires proactive planning. Key factors include controlling lifestyle inflation, factoring in inflation’s long-term impact, and prioritizing health to reduce future healthcare expenses.
A well-rounded spending plan, delaying Social Security benefits, and optimizing tax strategies will also help maintain financial security. Lastly, working a little longer and continuing to invest wisely ensures your retirement assets grow.
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In a future where people stop aging at 25, but are engineered to live only one more year, having the means to buy your way out of the situation is a shot at immortal youth. Will Salas is accused of murder and on the run with a hostage.
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A world-renowned physicist seeks gravity’s true nature and finds wisdom in embracing its force in her life
Claudia de Rham has been playing with gravity her entire life. As a diver, experimenting with her body’s buoyancy in the Indian Ocean. As a pilot, soaring over Canadian waterfalls on dark mornings before beginning her daily scientific research. As an astronaut candidate, dreaming of the experience of flying free from Earth’s pull. And as a physicist, discovering new sides to gravity’s irresistible personality by exploring the limits of Einstein’s general theory of relativity. In The Beauty of Falling, de Rham shares captivating stories about her quest to gain intimacy with gravity, to understand both its feeling and fundamental nature. Her life’s pursuit led her from a twist of fate that snatched away her dream of becoming an astronaut to an exhilarating breakthrough at the very frontiers of gravitational physics.
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