PALs Researcher Portfolio 2017-18

School of Pharmacy & Life Sciences Research Portfolios

260117- 025

2017/2018

www.rgu.ac.uk/pals

Staff Listed

WELCOME ”

The School of Pharmacy and Life Sciences is the largest school in Robert Gordon University (RGU) comprising over 50 academic staff.

In 2013, the School moved to modern, purpose-build accommodation equipped with world-class laboratory and support facilities.

The School currently delivers undergraduate courses in Biomedical Sciences, Dietetics, Forensic and Analytical Science, Nutrition, and Pharmacy along with postgraduate MSc courses in Clinical Pharmacy Practice and Instrumental Analytical Sciences. The School also has a thriving postgraduate research programme. There are currently more than 40 doctoral students undertaking research in the School and research degrees are offered leading to the awards of Master of Research, Doctor of Philosophy and the Doctorate of Professional Practice.

To complement this portfolio of taught courses and postgraduate teaching, staff in the School conduct high-impact research

under two main themes; Translational Research and Clinical Practice Research. Key areas within these themes include Analytical, Biological and Pharmaceutical Sciences, Dietetics and Pharmaceutical Care. External grant income in excess of £3M has been secured for session 2016-17 from a variety of sources including Research Councils, Scottish Government, Pharma industry and medical charities. Collaborative projects, including consultancies, are underway with Universities and Research Centres in the Middle East, Europe and the United States.

Thank you for enquiring about research in the School of Pharmacy and Life Sciences at RGU. This introduction and welcome can only provide a brief overview of some of the research that is undertaken in the School.

Please contact me, or any of the staff listed in this guide, to discuss your research interests.

”

Prof Donald Cairns Head of School, PALS.

TRANSLATIONAL RESEARCH Theme lead Prof. Susan J. Duthie Dr. Gemma Barron Prof. Donald Cairns Dr. Stuart Cruickshank Dr. Alberto Di Salvo Dr. Christine Edwards Dr. Carlos Fernandez Dr. Marie Goua Dr. Graeme Kay Dr. Rachel M. Knott Dr. Colin Thompson Prof. Paul Kong Thoo Lin Prof. Linda A. Lawton Dr. Lindsey Masson Dr. Kerr H. Matthews Dr. Barbara McKenzie Prof. Wolfram Meier-Augenstein Dr. Simon Officer Dr. Iain Rowe Dr. Kyari Yates PRACTICE RESEARCH Theme lead Prof. Derek Stewart Dr. Scott Cunningham Prof. Lesley Diack Dr. Katie MacLure Dr. Myra Mackensie-Fraser Dr. Noelle O’Driscoll Dr. Alison Strath Dr. Antonella Tonna Page 1

TransLATIONAL RESEARCH

Optimum health & wellbeing • diet & health • natural products • vascular health; • clinical dietetics • public health policy) Drug discovery, novel antimicrobial technologies and nanomaterials • natural products • drug & novel matrices design Environmental monitoring • sensors • clean technology • bioactive natural products & algal biotechnology

Prof. Susan J. Duthie

Email

Transitional REsearch THEME LEADER

s.j.duthie@rgu.ac.uk

Professor and Associate Head of School (PALS)

Telephone

ResearchGate https://www.researchgate.net/profile/Susan_Duthie Orcid Link http://orcid.org/0000-0002-7990-4437 RGU Link http://www.rgu.ac.uk/dmstaff/duthie-susan Professor Duthie leads translational research

models and in human case-control and intervention

within PALS. Her expertise centers around how

studies. Moreover, she has investigated how gene-

diet affects human health and particularly how

nutrient interactions influence risk of malignancy,

nutrition influence cell function and genomic

specifically how polymorphisms in key folate

stability. She has determined mechanistically

metabolising enzymes influence genomic stability

how specific phytochemicals (including

and incidence of colorectal cancer in humans and

flavonoids, antioxidant vitamins and folic acid)

has demonstrated how intervention with folic acid

influence DNA damage and DNA repair.

decreases DNA damage in healthy volunteers. With regards to CVD, she has shown how folate status

Recently, Prof. Duthie’s work has centred on how B vitamins influence human health and disease. She has established how folate status influences genomic stability, global protein expression (proteomics) and genome-wide DNA methylation in vitro, in rodent

alters protein expression and DNA methylation status in human aorta smooth muscle cells and that longterm B vitamin deficiency increases atherosclerosis by perturbing vascular lipid metabolism in transgenic ApoE mice.

1. Increasing fruit and vegetable intake by dietary intervention: impact on nutritional biomarkers and attitudes to dietary change. Duthie SJ, Duthie GG, Russell WR, Kyle JAM, Macdiarmid, J, Rungapamestra, V, Stephen, S, Megias-Baeza C , Kaniewska JJ, Shaw, L, Milne L, Bremner D, Ross K, Morrice P , Pirie LP, Horgan G and Bestwick CS. Brit. J. Nutr., (under review).

2. B vitamin deficiency alters the expression of key proteins that regulate vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic mice. Duthie SJ, Beattie JH, Gordon M-J, Pirie LP, Reid MD, Duncan GJ, Horgan G and McNeil CJ. Genes & Nutrition (2015), 10 (1): 446-457.

3. Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 hour fast provides evidence of subtle effects on genes regulating inflammation and apoptosis as well as energy metabolism. Elliot RM, de Roos B, Duthie SJ, Boiwman FG, Rubio-Aliaga I, Crosley LK, Mayer C, Horgan G, Polley AC, Heim C, Coort SL, Evelo CT, Mulholland F, Daniel H, Mariman EC and Johnson T. Genes & Nutrition (2014), 9; 432-443.

+44 (0) 1224 262815 Research Interests •Mechanisms • of action of dietary nutrients on human health and disease •Impact • of plant compounds including phytophenols, flavonoids and anthocyanins on human health; cancer and vascular disease •Effect • of micronutrients on cancer risk; differential effects of diet and supplements on malignant transformation •Impact • of B vitamins and antioxidants on cognitive function and dementia in the elderly •Impact • of natural products from underused ethnic foods on human health Page 3

Dr. Gemma Barron

Email

BSc (Hons), PhD, MRSC, MRSB

g.barron@rgu.ac.uk

Lecturer in Biomedical Sciences, Researcher (CORE).

Telephone

ResearchGate https://www.researchgate.net/profile/Gemma_Barron Orcid Link http://orcid.org/0000-0003-2217-0900 RGU Link http://www.rgu.ac.uk/dmstaff/barron-gemma

+44 (0) 1224 263154

Dr Barron’s qualifications include a PhD in

vitro (skin, brain, bladder and oesophageal cancer

Medicinal Biochemistry (2010) and First Class

cell lines).

BSc Honours degree in Forensic Science (2006) both from Robert Gordon University, Aberdeen.

Gemma joined Robert Gordon University (2013-present) as a Research Fellow in the Institute of

Research Interests •Angiogenesis • at the cellular/ molecular level

Health and Wellbeing Research. In September 2015, She moved to the University of Dundee (2010-2013)

she joined the School of Pharmacy and Life Sciences

to undertake post doctoral research on a FP7-SME

as a Part-Time Lecturer and Part-Time Research

funded project investigating the early detection of

Fellow within the Centre for Obesity Research and

cancer using photonic crystals lasers (EDOCAL) in

Education (CORE).

1. Kopsida M, Barron GA, Bermano G, Goua M, Kong Thoo Lin P. Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells Organic & Biomolecular Chemistry, Org. Biomol. Chem., 2016,14, 9780-9789 DOI: 10.1039/C6OB01850E

•Cancer • therapeutics: DNA damage and repair •Cancer • diagnostics: Biomarkers in disease •Effect • of natural products in cancer

2. Barron GA, Goua M, Kuraoka I, Bermano G, Iwai S, Kong Thoo Lin P. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions, 2015;242:307-315. DOI:10.1016/j.cbi.2015.10.017 3. Barron GA, Bordet E, Goua M, Bermano G. Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. Current Angiogenesis, 2014;3(3):152-163. DOI: 10.2174/22115528 03666141113211829 4. Barron GA, Valentine R, Moseley H, Brancaleon L, Hill C, Woods JA. Porphyrin profile in four human cell lines after supplementation with 5-aminolaevulinic acid and its methyl ester. Photodiagnosis and Photodynamic Therapy, 2013;10:654-663. DOI: 10.1016/j.pdpdt.2013.08.004 5 Barron GA, Moseley H and Woods JA. Differential sensitivity in cell lines to photodynamic therapy in combination with ABCG2 inhibition. Photochemistry and Photobiology B: Biology 2013;126:87-96. doi: 10.1016/j.jphotobiol.2013.07.003

Page 4

Prof. Donald Cairns

Email

BSc (Hons), PhD, FRPharmS, C.Sci, C.Chem, FRSC.

d.cairns@rgu.ac.uk

Professor and Head of School (PALS).

Telephone

ResearchGate https://www.researchgate.net/profile/Donald_Cairns Orcid Link http://orcid.org/0000-0001-7086-7441 RGU Link http://www.rgu.ac.uk/dmstaff/cairns-donald

+44 (0) 1224 262501

Professor Cairns leads the strategic planning,

year spent in hospital pharmacy, returned to

coordination, development and supervision

Strathclyde to undertake a PhD on the synthesis and

of academic work at the School of Pharmacy

properties of benzylimidazolines.

and Life Sciences. He is a member of the GPhC, the Royal Pharmaceutical Society, the Association of Pharmaceutical Scientists and in 2008 was made a Fellow of the Royal Society of Chemistry. He has served as a member of the British Pharmacopoeia Commission and an Expert Advisory Group of the Commission on Human Medicines. In 2015 he was made a Fellow of the Royal Pharmaceutical Society.

Following a year as a post-doctoral research fellow, Dr Cairns moved to Leicester Polytechnic (now De Montfort University) where he held a five-year lectureship in pharmacy. In 1992 he was appointed senior lecturer in medicinal chemistry in Sunderland School of Pharmacy and in 2003 moved to a post of Associate Head of the School of Pharmacy at The Robert Gordon University in Aberdeen. In 2006,

Research Interests •The • design, synthesis and evaluation of novel prodrugs for the treatment of nephropathic cystinosis •The • design, synthesis and evaluation of selective anticancer agents targeted to high-order forms of DNA

he was promoted to Professor of Pharmaceutical Dr Cairns graduated in pharmacy from the University

and Medicinal Chemistry at RGU and in 2012 was

of Strathclyde in 1980 and after a pre-registration

appointed Head within the School.

•The • molecular modelling of drug / DNA interactions

1. McKenzie, Kay, Matthews, Knott and Cairns ‘The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ.’ International Journal of Pharmaceutics 490, 2015, pp. 1-8 DOI information: 10.1016/j.ijpharm.2015.05.023 2. Benylles, Cairns, Cox and Kay ‘Three salts from the Reaction of Cysteamine and Cystamine with l (+) Tartaric Acid’ Acta Crystallographica Section C, 2013, C69, 658-664, doi: 10.1107/S0108270113012377 3. Buchan, Kay, Matthews and Cairns, ‘Suppository formulations as a potential treatment for Nephropathic Cystinosis’ J. Pharm. Sci, 2012, DOI 10.1002/jps.23246 4. Chahrour, Cairns and Omran “Small molecule Kinase Inhibitors as Anti-Cancer Therapeutics”, Mini Rev. Med. Chem. 2012, 12 (5), 399-411

Page 5

Dr. Stuart Cruickshank BSc PhD

Email

s.f.cruickshank@rgu.ac.uk Telephone

Lecturer in Pharmacology Orcid Link http://orcid.org/0000-0003-2146RGU Link http://www.rgu.ac.uk/dmstaff/cruickshank-stuart

Dr Cruickshank has research skills in the areas

gives insight as to how environmental factors are likely

of whole-cell patch clamp and extracellular

to impact vascular function. Long term integration of

electrophysiology, epifluorescent microscopy,

hydrostatic pressures affect neuronal function and

small vessel wire myography, time series

the use of a model invertebrate system has provided

analysis (including MESA and autocorrelation).

insight as to how, over extended periods, sensory

+44 (0) 1224 262535

Research Interests •Vascular • smooth muscle physiology

feedback modulates interneuron activity.

His research interests are varied but include understanding how environmental cues, for example

Dr Cruickshank graduated with a PhD from University

pressure, affect physiological function. The partial

of Aberdeen followed by post-doctoral position at

pressure of oxygen affects vascular smooth muscle,

University of Strathclyde. For the last 13 years he has

and understanding how such stimulus is transduced

been employed as a lecturer in RGU.

•Pulmonary • vein physiology •[Ca2+]i • regulation •Ion • channel function •Invertebrate • neurophysiology

1. Dopinescu C, Widmer H, Rowe I, Wainwright C, Cruickshank SF (2012). Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. Am. J.Physiol. (Lung Cell.Mol.Physiol.) 303(5):L476-86.doi:10.1152/ ajplung.00157.2012 2. Sunil Jit RJ Logantha, Stuart F Cruickshank, Edward G Rowan, Robert M Drummond (2010) Spontaneous and electrically evoked Ca2+ transients in cardiomyocytes of the rat pulmonary vein. Cell Calcium, 48(2-3):150-60. doi: 10.1016/j. ceca.2010.08.002 3. Yildiz I, Deniz E, McCaughan B, Cruickshank SF, Callan JF, Raymo FM. (2010) Hydrophilic CdSe-ZnS core-shell quantum dots with Reactive Functional Groups on Their Surface. Langmuir 26(13):11503-11 doi: 10.1021/la1010488 4. Yildiz I, McCaughan B, Cruickshank SF, Callan JF, Raymo FM. (2009) Biocompatible CdSe-ZnS core-shell quantum dots coated with hydrophilic polythiols. Langmuir 16;25 (12):7090-6 doi: 10.1021/la900148m.

5. .Fraser PJ, Cruickshank SF, Shelmerdine RL, Smith LE, (2008). Hydrostatic Pressure Receptors and Depth Usage in Crusta-

Page 6

Dr. Alberto Di Salvo BSc (Hons) PhD MRSC

+44 (0) 1224 262581

Orcid Link http://orcid.org/0000-0003-2091-6473 RGU Link http://www.rgu.ac.uk/albertodisalvo

Dr Di Salvo’s research interests lie in the area

followed by a PhD in Medicinal Chemistry Design

of selective toxicity and anticancer agents.

and synthesis of tumour activated oligopeptide

His key research skills include multistep

prodrugs that exploit the proteolytic activity of MMP-

synthesis, asymmetrisation (enzymatic and

98168 .

non-enzymatic), preparative chromatography spectrometry.

Dr Di Salvo also worked at the Rega Institute for Medical Research, Belgium and the City College of New York, before joining the School of Pharmacy and

Dr Di Salvo attended Edinburgh Napier University

a.di-salvo@rgu.ac.uk Telephone

Lecturer in Pharmaceutical Sciences

and structure elucidation by NMR and mass

Email

Life Sciences in Aberdeen..

Research Interests •Medicinal • chemistry •Organic • spectroscopy •Structural • elucidation with 2D NMR

and completed a BSc (Hons) in Applied Chemistry

1. Di Salvo, A; Dugois, P; Tandeo, D; Peltekian, M; Lin, PKT; Synthesis, cytotoxicity and DNA binding of oxoazabenzo[de]anthracenes derivatives in colon cancer Caco-2 cells; EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 69, 754-761.

2. Omran, Z; Kay, G; Di Salvo, A; Knott, RM; Cairns, D; PEGylated derivatives of cystamine as enhanced treatments for nephropathic cystinosis; BIOORGANIC & & MEDICINAL CHEMISTRY LETTERS; 2011, 21 (1), 45-47.

3. Liu, F., Di Salvo, A., Herdewijn, P. 2008, Synthesis of 2818c-Cyclohexenylnucleosides and Corresponding CeNA Building Blocks, Current Protocols in Nucleic Acid Chemistry, June 2008, Volume 1, Unit 1.20.

4. Dias, N., Goossens, J-F., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., Bernal, J., Turnbull, A., Mincher, D.J., and Bailly, C. 2005, 8165Oxoazabenzo[de]anthracenes conjugated to amino acids: synthesis and evaluation as DNA-binding antitumour agents8166, Bioconjugate Chemistry, 16, 949-958.

5. Van Valckenborgh, E., Mincher, D.J., Di Salvo, A., Van Riet, I., Young, L., Van Camp, B., and Vanderkerken, K. 2005, 8165Targeting an MMP-9-activated prodrug to multiple myeloma diseased bone marrow: a proof of principle in the 5T33MM mouse model8166, Leukemia, 19, 1628-1633

Page 7

Dr. Christine Edwards

Email

BSc, PHd

c.edwards@rgu.ac.uk

Researcher and lecturer in microbial biotechnology,

Telephone

ResearchGate https://www.researchgate.net/profile/Christine_Edwards6 Orcid Link http://orcid.org/0000-0001-5180-9043 RGU Link http://www.rgu.ac.uk/dmstaff/edwards-christine

Dr Edwards developed her interest in bioactive

In 1994, Dr Edwards joined Biotage as a technical

natural products, in particular toxins produced

support specialist for purification products from R & D

by cyanobacteria, whilst engaging in her

to production scale. This involved collaboration with

postdoctoral research at the University of

customers on method development and optimisation,

Dundee.

and resulted in several publications.

Her current research group has facilities for

In 2005, she joined the School of Pharmacy and Life

cyanobacterial culture, chemical analysis (high

Sciences to resume a more active role in research,

performance liquid chromatography with photodiode

with emphasis on cyanobacterial toxins, and their

array, fluorescence, mass, evaporative light scattering

occurrence and fate in the environment. She has many

detection), bioassay, and chromatography purification

years experience on the production of high quality

suite.

bioactive compounds for research tools.

+44 (0) 1224 262839

Research Interests •Production • of Bioactive compounds •Exploitation • of whisky waste for high values compounds •Analysis • and removal of cyanotoxins (water/shellfish) •Microbial • biotechnology

1. Delgado-Baquerizo, M, Giaramida, L., Reich, P.B., Khachane, A.N., Hamonts, K., Edwards, C., Lawton, L.A., Singh, B.K. (2016) Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. Journal of Ecology (accepted for publication).

2. Photos-Jones, E., Edwards, C., Haener, F., Keane, C., Lawton, L.A., Leanord, A., Perdikatsis, V. (2016) Archaeological Medicinal Earths as Antibacterial Agents: the case of the Basel Lemnian sphragides. Geology and Medicine: Historical Connections (accepted for publication).

3. Faassen, E.J., Antoniou,M.G., Beekman-Lukassen, W., Blahova, L., Chernova, E., Christophoridis, C., Combes, A., Edwards, C., Fastner, J., Harmsen, J., Hiskia, A., Ilag, L.L., Kaloudis, T., Lopicic, S., Lürling, M., Mazur-Marzec , H., Meriluoto, J., Porojan, C., Viner-Mozzini, Y Zguna, N. (2016) A Collaborative Evaluation of LC-MS/MS Based Methods for BMAA Analysis: Soluble Bound BMAA Found To Be an Important Fraction. Marine Drugs (accepted for publication).

4. Pestana, C. J., Edwards, C., Prabhu R., Robertson, P.K.J., Lawton, L.A.. (2015) Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2coated glass microspheres. Journal of Hazardous Materials 300, 347–353.

Page 8

Dr. Carlos Fernandez MChem PhD CChem CSci MRSC MInstP MECS Orcid Link http://orcid.org/0000-0001-6588-9590 RGU Link http://www.rgu.ac.uk/dmstaff/fernandez-carlos

Dr Fernandez gained his MChem at the

Reactions”. In 2010 he took a role as a Senior

University of Almeria (Spain) in 2002 and

Scientist at Oxtox Ltd. (Manchester) working on

then moved to the UK where he undertook a

the development of an Electrochemical Sensor

research year at the University of Durham in

using Screen-Printed Electrodes to detect

2003 investigating Ruthenium complexes using

methamphetamine, ampthetamine, cocaine and

X-Ray diffraction.

ecstasy in oral fluid for the purpose of roadside testing. In 2013 he took a position at RGU in The

Hull where he took a four year position as a GTA (Graduate Teaching Assistant) along with a PhD. He obtained his PhD in 2009 on “Electrocatalytic

c.fernandez@rgu.ac.uk Telephone

Lecturer in Analytical Chemistry

In 2005 Dr Fernandez moved to the University of

Email

+44 (0) 1224 262559

Research Interests •Liquid-Liquid • interface & Electrochemistry at the Three Phase Boundary (droplets) & Electrochemiluminescence

School of Engineering as a Research Fellow/Business Development Officer. In 2014 he was appointed as

•Bioelectrochemistry •

a Lecturer in Analytical Chemistry at the School of Pharmacy & Life Sciences.

•Forensic • Electrochemistry •Graphene • Electrochemistry

1. Fernandez, T. Ravishankar, K. Sureshkumar, S. Teixeira and T. Ramakrishnappa. Electroanalysis, 2016, 28, 3, 452-461: Ag Doped Titanium Dioxide Nanocomposite-Modified Glassy Carbon Electrode as Electrochemical Interface for Catechol Sensing 2. Fernandez, M. M. Sundaram, A. Biswal, D. Mitchell and R. Jones: Physical Chemistry Chemical Physics (PCCP), 2016, 18, 4711 – 4720: Correlation Among Physical and Electrochemical Behaviour of Nanostructured Electrolytic Manganese Dioxide from Leach Liquor and Synthetic for Aqueous Asymmetric Capacitor 3. Fernandez, L. Cruickshank, S. Officer, P. Pollard, R. Prabhu and M. Stutter. Analytical Sciences, 2015, 31,623-627:Rare Elements Electrochemistry: The Development of a Novel Electrochemical Sensor for the Rapid Detection of Europium in Environmental Samples Using Gold Electrode Modifying with 2-Pyridinol-1-Oxide 4. Fernandez, S. Kruanetr and P. Pollard. Journal of The Electrochemical Society, 2014, 161, (1), H36-H40: Electroanalytical Sensing of Ketamine Using Electrogenerated Chemiluminescence

•Development • sensors for Environmental Applications •Nanocomposites • & Energy Storage Devices (Capacitors)

5. Fernandez, J. Smith, J. Metters, D. Kampouris, O.Sutcliffe and C. Banks. Analyst, 2013, 138, 6185-6191: Forensic Electrochemistry: The Electroanalytical Sensing of Rohypnol® (Flunitrazepam) using Screen Printed Graphite Electrodes without

Page 9

Dr. Marie Goua

Email

BSc(Hons), PhD, CBiol, MRSB, FHEA

m.goua@rgu.ac.uk

Lecturer in Biosciences

Telephone

ResearchGate https://www.researchgate.net/profile/Marie_Goua Orcid Link http://orcid.org/0000-0003-1609-4366 RGU Link http://www.rgu.ac.uk/mariegoua

+44 (0) 1224 262898

Dr Goua’s key research interests include

PhD studies she has been interested in assessing

nutrient gene interaction, cardiovascular

the effects of various fatty acids on inflammatory

disease and cancer in relation to inflammation.

mechanisms such as cytokine expression in prostate

Her skills lie in the areas of cell culture, RNA

and breast cancer cells.

studies, DNA damage, protein studies and flow cytometry.

In line with the research on breast cancer prevention, she is interested in understanding the molecular

Dr Goua carried out her PhD at the Rowett

mechanisms involved in the disease by studying the

Research Institute where she studied the effects of

inflammatory and oxidative pathways in relation to

polyunsaturated fatty acids on adhesion molecules

new anti-cancer compounds and, more importantly,

in relation to atherosclerosis. Since finishing her

natural products.

1. Barron GA, Goua M, Kuraoka I, Bermano G, Iwai S, Kong Thoo Lin P-Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-biological interactions (2015) 242:307-315.

2. Kapravelou G , Martínez R, Andrade AM, Nebot E, Camiletti D, Aparicio V, López-Jurado M, Aranda P, Arrebola 2 F, Fernández-Segura E, Bermano G, Goua M, Galisteo M, and Porres JM- Aerobic interval exercise improves parameters of Non Alcoholic Fatty Liver Disease (NAFLD) and other alterations of metabolic syndrome in obese Zucker rats. Applied Physiology, Nutrition and Metabolism, (2015), 40(12): 1242-1252.

Research Interests •Effects • of nutrients in diseases •Angiogenesis • at the cellular/ molecular level •Inflammation • and DNA damage •Natural • compounds and their effects in cancer, cardiovascular and neurodegenerative diseases •The • effect of different fatty acids on cardiovascular markers

3. Barron GA, Bordet E, Goua M, Bermano G. Modulation of Angiogenesis by Inflammatory Markers and the Role of Matrix Metalloproteinases in an Endothelial Cell/Fibroblast Co-Culture System. Current Angiogenesis (2014) 3(3):152-163.

4. Bermano G, Smyth E, Goua M, Heys S, Wahle K. Impaired expression of glutathione peroxidase-4 gene in peripheral blood mononuclear cells as a biomarker of increased breast cancer risk. Cancer Biomarkers (2010) 7:39-46.

5. Goua M, Mulgrew S, Frank J, Rees D, Sneddon AA and Wahle KWJ. Regulation of adhesion molecule expression in human vascular endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids (CLAs): involvement of the transcription factor NF-kB? Prostaglandins, Leukotrienes and Essential Fatty Acids (2008), 78(1):33-43.

Page 10

Dr. Graeme Kay

Email

FRSC, MAPS, SRPharmS, MCSFS

g.kay@rgu.ac.uk

Teaching Group Leader – Chemical Sciences

Telephone

ResearchGate https://www.researchgate.net/profile/Graeme_Kay Orcid Link http://orcid.org/0000-0003-4792-1598 RGU Link http://www.rgu.ac.uk/dmstaff/graeme-kay

+44 (0) 1224 262548

Dr Kay’s research projects have been

that he was employed at Edinburgh Napier University

in the area of medicinal, organic and

as a researcher in organo-medicinal chemistry. He

pharmaceutical chemistry. His key research

was educated at Edinburgh Napier University where

skills include organo-medicinal chemistry,

he gained a BSc (Hons) degree in Applied Chemistry

mass spectrometry, NMR and IR spectroscopy.

and a PhD in Anti-Cancer Medicinal Chemistry.

Specialist research facilities available to Dr Kay include the medicinal chemistry research laboratory and the NMR facility.

Research Interests •Design, • synthesis and bioevaluation of amino-substituted anthraquinones as potential anticancer agents

Dr Kay has received over £230,000 in funded research. Awards include:SPARKS, The Children’s Medical Research Charity and The Cystinosis

Dr Kay joined the University in 2005 after a brief spell

Foundation UK, and the Cystinosis Foundation of

in industry as a development chemist. Previous to

Ireland.

•Design, • synthesis and evaluation of novel pro-drugs for the treatment of Cystinosis •Design, • synthesis of non-invasive imaging agents in Atherosclerosis

1. B. McKenzie, G. Kay, K. H. Matthews, R. M. Knott and D. Cairns. The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ. International Journal of Pharmaceutics 490 (2015) 1–8. http://dx.doi.org/10.1016/j.ijpharm.2015.05.023 2. A. Benylles, D. Cairns, P. J. Cox and G. Kay. Three salts from the reactions of cysteamine and cystamine with L-(+)-tartaric acid. Acta Crystallographica Section C, Crystal Structure Communications. Volume 69, Part 6 (June 2013). DOI: 10.1107/ S0108270113012377

•Formulation • of cysteamine as a dosage form for ophthalmic delivery in Cystinosis

3. B. E. Buchan, G. Kay, K. H. Matthews and D. Cairns. Suppository formulations as a potential treatment for Nephropathic Cystinosis. Journal of Pharmaceutical Sciences, Volume 101, Issue 10, pages 3729–3738, October 2012. DOI: 10.1002/jps.23246 4. Omran, Z.; Kay, G.; Moloney, K. A.; Benylles. A.; Knott, R. M.; Cairns, D. Bioorganic & Medicinal Chemistry. Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis. 2011, doi:10.1016/j.bmc.2011.04.022 5. Omran, Z.; Kay, G.; Hector, E. E, Knott, R. M.; Cairns, D. Bioorganic & Medicinal Chemistry Letters. Folate pro-drug of cys-

Page 11

Dr. Rachel M. Knott

Email

BSc, MSc, PhD

r.knott@rgu.ac.uk

Reader, Molecular and Cell Biology

Telephone

ResearchGate https://www.researchgate.net/profile/Rachel_Knott Orcid Link http://orcid.org/0000-0002-4363-8974 RGU Link http://www.rgu.ac.uk/rachelknott

Dr Knott’s work is currently focused on

on the editorial panel of the Gavin Journal of Diabetes

the investigation of the mechanism(s) of

and is a member of the organising committee for the

endothelial cell changes in response to glucose

13 th Global Diabetes Conference and Medical Expo

concentration, pressure and oxygen tension

in Birmingham in 2016 . She has supervised research

in order to develop early interventions for

students and continues to be active in research skill

the prevention of diabetic retinopathy which

development recognising this to be an important

is a severe and debilitating complication of

element for the realisation of future research leaders.

diabetes.

Dr Knot graduated from Aberdeen University with Her work has taken her to many international and

a PhD in 1988. Prior to taking up employment at

national conferences and she has authored over 50

Robert Gordon University in 1999 she worked at

research papers, reviews and chapters in books. She

the Rowett Research Institute and the University of

is a reviewer for a number of different journals and is

Aberdeen.

1. Ibie, C. O., Thompson, C. J., Knott R. (2015) In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells International Journal of Pharmaceutics 12/2014; 479(1). DOI: 10.1016/j. ijpharm.2014.12.058 C. 2. Ibie, O., Thompson, C. J., Knott R. (2015) Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine Colloid and Polymer Science; DOI:10.1007/s00396-015-3561-4 3. Gadad, P. C., Matthews, K. H., & & Knott, R. M. (2013). Silymarin released from sterile wafers restores glucose impaired endothelial cell migration. International Journal of Pharmaceutics, 457 (1), 40-49.

4. Gadad, P. C., Matthews, K. H., & & Knott, R. M. (2013). Role of HIF1alpha and PKC beta in mediating the effect of oxygen and glucose in a novel wound assay. Microvascular Research, 88 , 61-9.

+44 (0) 1224 262524 Research Interests •Ex • vivo explants as model systems for the study of the vascular complication of diabetes •Molecular • mechanisms of vascular change in endothelial cell response due to high and/ or fluctuating concentrations of glucose and oxygen •Non-alcoholic • fatty liver disease: role of vascular change in the onset and progression of hepatic damage •Use • of bioinformatics to inform gene function and disease association in the search for biomarkers of disease and pharmacogenomic predictors

5. Thompson, C., Cheng, W. P., Gadad, P., Skene, K., Smith, M., Smith, G., McKinnon A, Knott R. (2011). Uptake and transport of novel amphiphilic polyelectrolyte-insulin nanocomplexes by caco-2 cells-towards oral insulin. Pharmaceutical Research, 28 (4), 886-896.

Page 12

Dr. Colin Thompson

Email

PhD, MAPS, MRSC, FHEA

c.thompson@rgu.ac.uk

Researcher and lecturer in Drug Delivery

Telephone

ResearchGate https://www.researchgate.net/profile/Colin_Thompson Orcid Link http://orcid.org/0000-0002-9571-9434 RGU Link http://www.rgu.ac.uk/dmstaff/thompson-colin

+44 (0) 1224 262561

Dr Thompson has been an undergraduate, postgraduate and research fellow within the School and a lecturer in Drug Delivery since July 2009.

Research Interests •Targeted • drug delivery via I/V route using polymeric nanoparticles and polymer-drug conjugates

He teaches a variety of undergraduate modules across all four years on the MPharm course as well as other life sciences undergraduate and postgraduate degrees. He is also a Fellow of the Higher Education Academy and a Member of the Academy of

•Buccal • delivery of drugs using natural and semi-synthetic polymers

Pharmaceutical Sciences and the Royal Society of Chemistry.

1. Ibie, C. O., Knott, R. and Thompson, C. J., 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International Journal of Pharmaceutics 479, 103-117.

2. Thompson, C.J., Hansford, D., Higgins, S., Rostron, C., Hutcheon, G.A. and Munday, D.L., 2009. Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. Journal of Microencapsulation 26(8), 676-683.

3. Chemically Modified Polyelectrolytes for Intestinal Peptide and Protein Delivery, by C. Thompson and W. P. Cheng. In: Peptide and Protein Delivery, C Van der Walle (Ed.). Elsevier: London, 2011.

4. Cheng, W. P., Thompson, C., Ryan, S. M., Aguirre, T., Tetley, L. and Brayden, D. J., 2010. In vitro and in vivo characterisation of a novel peptide delivery system: Amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes. Journal of Controlled Release 147(2), 289-297.

5. Thompson C. J., Cheng W. P., Gadad P., Skene K., Smith M., Smith G., McKinnon A., Knott R., 2011. Uptake and Transport of Novel Amphiphilic Polyelectrolyte-Insulin Nanocomplexes by Caco-2 Cells-Towards Oral Insulin. Pharmaceutical Research, 28(4), 886-896.

•Solid • lipid nanoparticles and nanostructured lipid carriers for drug solubilisation and delivery •Amphiphilic • polymers and polyelectrolytes for macromolecule delivery •Microencapsulation • of drugs using biodegradable polymers Page 13

Prof. Paul Kong Thoo BSc PhD FRSC CChem FHEA ResearchGate https://www.researchgate.net/profile/Paul_kong_thoo_lin Orcid Link http://orcid.org/0000-0002-7090-246X RGU Link http://www.rgu.ac.uk/dmstaff/kong-thoo-lin-paul

Since joining RGU, Prof. Kong Thoo Lin has

plants materials and the study of their biological

been active in the design and synthesis of

activities that can potentially be developed to fight

novel compounds/polymers with ‘intelligent’

neurodegenerative diseases.

functions that can be applied as sensors, parasites), to elucidate mechanism of drug action and provide effective drug delivery.

+44 (0) 1224 262818 Research Interests •Targeting • Histone Deacetylase Enzymes with novel compounds in cancer cell lines

From 1987 till 1992, Professor Paul Kong Thoo Lin worked at the MRC, Laboratory of Molecular Biology, Cambridge, UK, where he was involved in the synthesis of novel degenerate/universal bases

More recently his research has included the

p.v.s.kong-thoo-lin@rgu.ac.uk Telephone

Professor of Medicinal Chemistry

to treat and manage diseases (cancer and

Email

and their incorporation in oligonucleotides.

isolation and identification of novel compounds from

1. Renato Gil, Célia G. Amorim, Laura Crombie, Paul Kong Thoo Lin, Alberto Araújo and Maria da Conceição Montenegro. Study of a novel bisnaphthalimidopropyl polyamine as electroactive material for perchlorate-selective potentiometric sensors (2015). Electroanalysis, 27, 1 – 12 (DOI: 10.1002/elan.201500275)

2. Jennifer Noro, Joana Maciel, Diana Duarte, Ana Cristina Dias Olival, Catarina Baptista, Anabela Cordeiro da Silva, Maria José Alves, Paul Kong Thoo Lin. Evaluation of New Naphthalimides as Potential Anticancer Agents Against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT-15 Cell Lines (2015). Organic Chem Curr Res, 4:2 http://dx.doi. org/10.4172/2161-0401.1000144.

3. Gemma A. Barron, Marie Goua, Isao Kuraoka, Giovanna Bermano, Shigenori Iwai, Paul Kong Thoo Lin. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-Biological Interactions 242 (2015) 307-315.

4. Marcela A. Segundo, Vera L. R. G. Abreu, Marcelo V. Osório, Sonia Nogueira, Paul Kong Thoo Lin, Anabela Cordeiro-da-Silva , Sofia A. C. Lima. Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles. Journal of Pharmaceutical and Biomedical Analysis. 120 (2016) 290–296.

•Regulation • of apoptosis and DNA damage in cancer cells •Design • and synthesis of multi target molecules against cancer •Anti-inflammatory • drug design based on natural products •The • design and application of novel drug delivery systems •Chemical • profiling and biological activities of plant pomace extracts

Page 14

Prof. Linda A. Lawton

Email

BSc PhD

l.lawton@rgu.ac.uk

Professor of Environmental Microbiology

Telephone

ResearchGate https://www.researchgate.net/profile/Linda_Lawton Orcid Link http://orcid.org/0000-0002-7840-5310 RGU Link http://www.rgu.ac.uk/dmstaff/lawton-linda

+44 (0) 1224 262823

Prof. Lawton leads an internationally-

of microcystins, the main group of cyanotoxins.

respected research team, CyanoSol, which has

This methodology has now been published as an

a world wide reputation in the study of the

approved method and has been cited over 600

environmental impact and monitoring of natural

times in scientific literature. Her research has now

toxic metabolites from cyanobacteria (blue-

extended into broader environmental concerns

green algae).

such as desalination and waste valorisation through using green chemical and biotechnology. She has

These toxins pose a significant and increasing risk to human health in both drinking water and at recreational sites hence much of the work is involved in water treatment strategies including advanced oxidative techniques. Her group has pioneered the most widely used analytical procedure for analysis

successfully attracted funding from a wide range of sources including the Research Councils, EU, Charities and Industry. The reputation of her group has led to many fruitful research collaborations both in the UK and around the world including, Germany, Finland, Denmark, Poland, Cyprus, Spain & France.

1. Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning, M Delgado Baquerizo, L Giaramida, PB Reich, AN Khachane, K Hamonts, C Edwards, LA Lawton, BK Singh Journal of Ecology 2016 DOI: 10.1111/1365-2745.12585 2. Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photocatalysis G Zhang, C Ni, X Huang, A Welgamage, LA Lawton, PKJ Robertson, JTS Irvine, Chemical Communications 52 (8), 16731676, 2016 DOI: 10.1039/c5cc09075j 3. Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres CJ Pestana, C Edwards, R Prabhu, PKJ Robertson, LA Lawton Journal of hazardous materials 300, 347-353, 2015 DOI: 10.1016/j.jhazmat.2015.07.016 4. Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq International Journal of Molecular Sciences M Khurram, LA Lawton, C Edwards, M Iriti, A Hameed, MA Khan, FA Khan, International journal of molecular sciences 16 (9), 20290-20307, 2015

Research Interests •Production, • detection and removal of cyanotoxins including microcystins, cylindrospermopsin and neurotoxins •Isolation • and characterisation of bioactive compounds from cyanobacteria and other novel biological sources •Algal • biotechnology for biofuels, material and food additives (omega-3, vitamins, pigments) •Water • quality, treatment and advanced oxidative methods for drinking water and waste water remediation •Application • of photocatalytic technologies to environmentally sustainable energy and chemicals Page 15

Dr. Lindsey Masson

Email

BSc, MSc, PhD, RNutr

l.f.masson@rgu.ac.uk

Researcher and Lecturer in Nutrition

Telephone

ResearchGate https://www.researchgate.net/profile/Lindsey_Masson Orcid Link http://orcid.org/0000-0002-3760-8189 RGU Link http://www.rgu.ac.uk/lindsey-masson

+44 (0) 1224 262856 Research Interests

Dr Masson’s main area of expertise is in

joining Robert Gordon University, she was employed

the use of dietary assessment methods in

by the University of Aberdeen This included 4 years

epidemiological studies (of both children and

as a Research Fellow in Epidemiology, and 6 years as

adults), statistical analysis of epidemiological

a Lecturer in Human Nutrition Epidemiology which

studies (including studies with a complex

included acting as Programme Coordinator for the

survey design), and systematic review

MSc Human Nutrition and Metabolism.

methodology. Lindsey is also a member of the Nutrition Society Scottish Section committee.

Dr Masson is a Registered Nutritionist with the UK Voluntary Register of Nutritionists, held by the

She obtained her BSc (Hons) Health Sciences, MSc

•Monitoring • food and nutrient intakes in Scotland •Use • of dietary assessment methods in epidemiological studies of cardiovascular disease, cancer and obesity •Improving • diet in cancer survivors

Association for Nutrition.

Human Nutrition and Metabolism, and PhD Human Nutrition from the University of Aberdeen. Before

•Systematic • literature reviews on gene-diet interactions, genotypedisease associations, and dietdisease associations

1. Macdiarmid JI, Wills WJ, Masson LF, Craig LC, Bromley C, McNeill G. (2015) Food and drink purchasing habits out of school at lunchtime: a national survey of secondary school pupils in Scotland. Int J Behav Nutr Phys Act 12(1):98. doi: 10.1186/ s12966-015-0259-4.

2. Thies F, Masson LF, Bofetta P and Kris-Etherton P. (2014) Oats and CVD risk markers: a systematic literature review. Br J Nutr 112(Suppl 2): S19-30. doi: 10.1017/S0007114514002281.

3. Thies F, Masson LF, Bofetta P and Kris-Etherton P. (2014) Oats and bowel disease: a systematic literature review. Br J Nutr 112(Suppl 2): S31-43. doi: 10.1017/S0007114514002293.

4. Thies F, Masson LF et al. (2012) Effect of a tomato-rich diet on markers of cardiovascular risk in moderately overweight, disease-free, middle-aged adults: a randomised controlled trial. Am J Clin Nutr 95(5): 1013-22. doi: 10.3945/ajcn.111.026286.

5. Masson LF et al. (2012) Survey of Diet Among Children in Scotland. (2010). Volume 1: Diet, Obesity and Physical Activity. Food Standards Agency in Scotland. http://www.foodstandards.gov.scot/survey-diet-among-children-scotland

Page 16

Dr. Kerr H. Matthews

Email

BSC(Hons) PhD CChem MRSC MAPS

k.h.matthews@rgu.ac.uk

Researcher and Lecturer in Pharmaceutics

Telephone

ResearchGate https://www.researchgate.net/profile/Kerr_Matthews Orcid Link http://orcid.org/0000-0002-8503-7157 RGU Link http://www.rgu.ac.uk/kerr-matthews

+44 (0) 1224 262525

Dr Matthews has research interests in the

Following his PhD in 1989, Dr Matthews’ expertise

general area of pharmaceutics. Since filing an

in polymer science has been applied in diverse areas

international patent on ‘Wafers for wounds’ in

of commercial interest from the manufacture of

2003, he has continued with the development

video tapes (3M UK Ltd.) to laminated papers (James

of this foundation technology as a topical

River Corp.); high tensile fibres and conducting gels

antimicrobial dressing, whilst teaching and

for lithium batteries (IRC in Polymer Science and

supervising at both undergraduate and

Technology, University of Leeds); artificial arteries

postgraduate levels.

and biomaterials (N.A.I.R., Japan); drug delivery

Research Interests •Antimicrobial • wafers as topical delivery systems for chronic wounds •Solid • and liquid drug delivery systems – design and manufacture

systems (Scherer DDS Ltd.); tissue repair & wound He has authored/co-authored 55 publications, including a book chapter, and has over 1000 citations.

healing (Pfizer) and topical antimicrobial therapies (RGU).

A review of drug delivery dressings co-authored in 2008 has been cited 570 times as of May 2016, placing it in the top 1% of its academic field.

Following a return to academia as a Lecturer in 2002 (University of Strathclyde) he subsequently moved to

•Hydrogels • – natural, synthetic and semi-synthetic polymers for pharmaceutical and biomedical application

Robert Gordon University in 2004.

•Biomaterials • 1. Bibi, S., Bremner, D.H., Macdougall-Heasman, M., Reid, R., Simpson, K., Tough, A., Waddell, S., Stewart, I.J., Matthews, K.H. 2015. A preliminary investigation to group disparate batches of licit and illicit diazepam tablets using differential scanning calorimetry. Anal.Methods., 7, 8597-8604. DOI: 10.1039/C5AY01711D 2. Labovitiadi, O., O’Driscoll, N.H., Lamb, A.J., Matthews, K.H. 2013. Rheological properties of gamma-irradiated antimicrobial wafers and in vitro efficacy against Pseudomonas aeruginosa, Int.J.Pharm., 453(2), 462-472. DOI: 10.1016/j.ijpharm.2013.06.005] 3. Labovitiadi, O., Lamb, A.J., Matthews, K.H. 2012. Lyophilised wafers as vehicles for the topical release of chlorhexidine digluconate – release kinetics and efficacy against Pseudomonas aeruginosa. Int.J.Pharm., 439(1-2), 157-164. DOI: 10.1016/j. ijpharm.2012.10.017 4. Boateng, J.S., Matthews, K.H., Stevens, H.N.E., Eccleston, G.M., 2008. Wound healing dressings and drug delivery systems - a review. J.Pharm.Sci., 97(8), 2892-2923. DOI: 10.1002/jps.21210

•Materials • Science – rheology and thermoanalytical techniques •Characterisation • of counterfeit medicines Page 17

Dr. Barbara McKenzie

Email

MPharm PhD MRSC

b.mckenzie1@rgu.ac.uk

Lecturer in Pharmaceutics

Telephone

ResearchGate https://www.researchgate.net/profile/Barbara_Buchan Orcid Link http://orcid.org/0000-0003-0409-908X RGU Link http://www.rgu.ac.uk/dmstaff/mckenzie-barbara

+44 (0)1224 262588

Dr McKenzie’s area of expertise is the

chemicals, from medicines to cosmetics. The current

formulation of medicines and particularly the

focus of her research is to establish an equivalent

formulation of ophthalmic and respiratory

technique which uses fertilised hen’s egg placental

medicines. She has investigated the potential

membranes. She has established a method which

to deliver medicines systemically, using

uses computer software to categorise the level of

biodegradable coatings for drugs with

irritation, using a technique which has been used by

challenging stability profiles.

forensic scientists.

Dr McKenzie has also developed an ophthalmic

Dr McKenzie is currently working with engineers

gel for the treatment of ocular complications of the

to develop an ex-vivo ophthalmic model, to aid the

rare disease Nephropathic cystinosis, and recently,

understanding of drug retention within the cornea

her work has centred on developing a quantitative

and ophthalmic tissues. Part of this work also involves

technique to measure ophthalmic irritation.

microdialysis, a technique designed to measure drug

Historically, the Draize rabbit test has been used

concentration within the aqueous humor.

Research Interests •Ophthalmic • drug delivery using gels and in-situ gelling polymers •Nephropathic • cystinosis, its complications and its treatment •Pulmonary • delivery of drugs for systemic delivery •Rectal • drug delivery for systemic treatment

widely to determine the ophthalmic irritation of many

.

1. Buchan B, Kay G, Heneghan A, Matthews KH, Cairns D. Gel formulations for treatment of the ophthalmic complications in cystinosis. International Journal of Pharmaceutics. 2010; 392, 1-2, p. 192-197.

2. Buchan B, Kay G, Matthews KH, Cairns D. Suppository formulations as a potential treatment for nephropathic cystinosis. Journal of Pharmaceutical Sciences. 2012; 101, 10, p. 3729-3738.

3. McKenzie B, Kay G. Eye gels for ophthalmic delivery. Expert review of Ophthalmology. 2015; 10(2), 127-133.

4. McKenzie B, Kay G, Matthews K H, Knott RM., & Cairns D. The hen’s egg chorioallantoic membrane (HET-CAM) test to predict the ophthalmic irritation potential of a cysteamine-containing gel: Quantification using Photoshop® and ImageJ. International Journal of Pharmaceutics. 2015; 490 (1–2), 1–8.

Page 18

Dr. Wolfram Meier-Augenstein PHd

Email

w.meier-augenstein@rgu.ac.uk

Professor

Telephone

Orcid Link http://orcid.org/0000-0002-0148-5332 RGU link http://www.rgu.ac.uk/dmstaff/meier-augenstein-wolfram

+44 (0) 1224 2500

Chemical analyses carried out in most analytical

While conventional spectroscopic and spectrometric

laboratories and, in particular in forensic science

methods prove chemical identity an argument can

laboratories primarily aim for the identification

be brought forward as a defence that although two

and comparison of various samples with the

substances in question are chemically identical they

intention of linking the samples of concern to a

are not the same, i.e. not of the same origin, hence

specific person or event. Identification is often

coming from a different source. Stable isotope

achieved through the characterization of one

analysis permits this contention to be tested since

or more specific sample constituents, while

it can provide the answer to the questions if two

comparison often involves the identification and

compounds or substances are truly identical, the

quantification of multiple components in the

given compound / substance can be linked to a

samples of interest.

particular geographic region.

1. W. MEIER-AUGENSTEIN, H.F. Kemp, E. R. Schenk, and J. R. Almirall (2014): “Discrimination of unprocessed cotton on the basis of geographic origin using multi-element stable isotope signatures”; Rapid Communications in Mass Spectrometry, 28, 545-552; DOI: http://dx.doi.org/10.1002/rcm.6811.

2. N. NicDaéid, S. Jayamana, W.J. Kerr, W. MEIER-AUGENSTEIN and H.F. Kemp (2013): “Influence of precursor solvent extraction on stable isotopic signatures of methamphetamine prepared from pseudo-ephedrine extracted from over the counter medicines using the Moscow and Hypophosporous routes”; Analytical and Bioanalytical Chemistry, 405 (9), 2931-2941; DOI: http://dx.doi. org/10.1007/s00216-012-6600-8.

3. N. NicDaéid, W. MEIER-AUGENSTEIN, H.F. Kemp and O.B. Sutcliffe (2012): “Using isotopic fractionation to link precursor to product in the synthesis of (±)-mephedrone. A new tool for combating ‘legal high’ drugs”; Analytical Chemistry, 84, 8691-8696; DOI: http://dx.doi.org/10.1021/ac3019069.

4. W. MEIER-AUGENSTEIN, H.F. Kemp and S. Hardy (2012): “Detection of Counterfeit Scotch Whisky by Bulk 2H and 18O Stable Isotope Analysis”; Food Chemistry, 133, 1070-1074; DOI: http://dx.doi.org/10.1016/j.foodchem.2012.01.084.

Research Interests •Human • provenancing •Elucidating • shifts in stable isotopic composition of synthetic drugs to link precursor/s to product •Elucidating • shifts in stable isotopic composition of explosives to link precursor(s) to product •Determining • authenticity and provenance of food by way of stable isotope analysis •Determining • authenticity and provenance of pharmaceutical drugs by way of stable isotope analysis Page 19

Dr. Simon Officer

Email

BSc(Hons) PhD MRSC

s.officer@rgu.ac.uk

Researcher and Lecturer in Analytical and Pharmaceutical Analysis

Telephone

ResearchGate https://www.researchgate.net/profile/Simon_Officer Orcid Link http://orcid.org/0000-0002-4126-0875 RGU Link http://www.rgu.ac.uk/dmstaff/officer-simon

+44 (0) 1224 262370 Research Interests

Dr Officer lecturers with expertise in

his PhD entitled “Alternative Strategies for Security

spectroscopy and laser based sensing having

Labelling/Encoding of Paper and Plastic Products”

been involved in a number of related research

in 2005 from The Robert Gordon University.

projects over the last 15 years. This has

Following this, he carried out his postdoctoral

involved applications of fluorescence sensing,

research advancing the technology developed from

UV excimer curing of surfaces, development

his PhD and helped expand the applications into the

of optical/polymeric materials including glass,

biomedical and environmental fields. This involved

development of photocatalytic coatings and

working on various projects funded by industry

fluorescent taggants.

(NCR Financial Solutions Group Ltd, Dundee, ITI

•Synthesis • and spectral analysis of lanthanide complexes for a variety of applications •Sol-gel • synthesis of nano and micro sized beads •Spectroscopy • and laser based sensing

Techmedia and Prime Technologies LLC) which led Dr Officer gained his 1st Class BSc Honours degree in Applied Chemistry in 2001 before completing

•Development • of a novel latent fingerprint development powder

to filing three patents. He was appointed as a lecturer in the School of Pharmacy & Life Sciences in 2008.

•Development • of a novel environmental soil tracer 1. CRUICKSHANK, L., OFFICER, S., POLLARD, P., PRABHU, R., STUTTER, M. AND FERNANDEZ, C., 2015, Rare Elements Electrochemistry: The Development of a Novel Electrochemical Sensor for the Rapid Detection of Europium in Environmental Samples Using Gold Electrode Modified with 2-pyridinol-1-oxide, Analytical Sciences, 31(7), pp. 623-627. doi:10.2116/analsci.31.623.

2. HAUSER, F.M., KNUPP, G. and OFFICER, S., 2015, Improvement in fingerprint detection using Tb(III)-dipicolinic acid complex doped nanobeads and time resolved imaging, Forensic Science International, 253, pp. 55-63. doi:10.1016/j.forsciint.2015.05.010

.

3. TIM CUSHNIE, T.P., ROBERTSON, P.K.J., OFFICER, S., POLLARD, P.M., MCCULLAGH, C. and ROBERTSON, J.M.C., 2009, Variables to be considered when assessing the photocatalytic destruction of bacterial pathogens, Chemosphere, 74(10), pp.

1374-1378. doi:10.1016/j.chemosphere.2008.11.012.

4. POLLARD, P., ADAMS, M., ROBERTSON, P.K.J., CHRISTIDIS, K., OFFICER, S., PRABHU, G.R., GOW, K., and MORRISON, A.R., 2008, Environmental Forensic Investigations: The Potential Use of a Novel Heavy Metal Sensor and Novel Taggants, In: K. RITZ, L. DAWSON and D. MILLER, ed. Criminal and Environmental Soil Forensics. Aberdeen: Springer. pp. 477-490

Page 20

Dr. Iain Rowe

Email

PHd

i.rowe@rgu.ac.uk

Lecturer

Telephone

ResearchGate https://www.researchgate.net/profile/Simon_Officer Orcid Link http://orcid.org/0000-0002-0148-5332 RGU link http://www.rgu.ac.uk/dmstaff/rowe-iain

+44 (0) 1224 2546

Dr Rowe is a Lecturer in Biomedical Science

Ongoing projects include work with Dr Stuart

at RGU with laboratory research focussed on

Cruickshank and Dr Helene Widmer (RGU) on:

electrophysiological and imaging techniques

the pulmonary vein as a therapeutic target in

to investigate: (i) the biophysical relationship

cardiovascular disease; the use of bioinformatics to

between potassium channel structure and

support the utilisation of farm animal tissue for more

function; (ii) post-translation modification

effective preclinical screening; and utilisation of data

of channel activity by metabolic signals and

on single-nucleotide polymorphisms to investigate ion

pharmacology; and (iii) the pharmacological

channel function. Non-laboratory research involves

modulation and physiological impact of

investigation of: the role of inter-professional learning

potassium channels in complex biological

(IPL); quality improvement methodology; and

systems.

cloud-based resources in pharmacy and biomedical

Research Interests

•Potassium • channel physiology •Potassium • channel pharmacology •Metabolic • regulation of ion channels

education.

•Ion • channels in pulmonary tissue 1. Ciprian Dopinescu, Helene Widmer, Iain Rowe, Cherry Wainwright, Dorothy McCaig & Stuart Cruickshank. (2012) Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. Am. J.Physiol. (Lung Cell.

Mol.Physiol.) 303, L476-86.

•Hypothalamic • control of appetite

2. Saleem F, Rowe ICM & Shipston MJ. (2009) Characterisation of BK channel splice variants using membrane potential dyes. Br. J.Pharmacol. 156, 143-152 3. McCartney, C.E., Huibant, J-M., McClaffery, H., Rowan, E.G., Shipston, M.J. & Rowe, I.C.M. (2005) A cysteine rich motif confers hypoxia sensitivity onto mammalian large conductance voltage and calcium activated (BK) channel α subunits. Proc. Natl. Acad.

Sci. USA. 102, 17870-17875 4. Rowe, I.C.M., Lee, K., Khan, R.N. & Ashford, M.L.J. (1997) Englitazone inhibits KATP and non-selective cation channels in CRI-G1 insulin-secreting cells. Br. J. Pharmacol. 121, 531-539.

5. Rowe, I.C.M., Boden, P.R. & Ashford, M.L.J. (1996) Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats. J. Physiol. 497.2, 365-377.

Page 21

Dr. Kyari Yates

Email

k.yates@rgu.ac.uk

BEng MSc PhD

Researcher, Environmental Chemistry; Lecturer, Forensic & Analytical Sciences, ResearchGate https://www.researchgate.net/profile/Kyari_Yates Orcid Link http://orcid.org/0000-0002-9919-4516 RGU Link http://www.rgu.ac.uk/dmstaff/yates-kyari

Dr Yates’s research interest lies in

He worked as an environmental Chemist at the

environmental chemistry with a particular

Fisheries Research Services Marine Laboratory

emphasis on fate, distribution and effects

(now Marine Scotland Science Marine Laboratory)

of persistent organic pollutants (POPs) and

Aberdeen before joining the Macaulay Land Use

passive sampling methodologies in various

Research Institute, Aberdeen (now James Hutton

matrices.

Institute) where he worked as an Analytical Chemist.

Dr Yates also has an interest in environmental sensing

In 2010 he was appointed a Lecturer with the School

and monitoring as well as the recycling of used

of Pharmacy and Life Sciences at RGU.

drilling fluids and remediation of oily waste waters.

1. Adegbotolu, V. U., Njuguna, J., Pollard, P., and Yates, K. (2014). Waste to Want: Polymer nanocomposites using nanoclays extracted from Oil based drilling mud waste. IOP Conf. Ser.: Mater. Sci. Eng. 64 012023 doi:10.1088/1757-899X/64/1/012023

Telephone

+44 (0) 1224 262884

Research Interests •• Fate, distribution and effects of persistent organic pollutants (POPs) •Development • of analytical methodologies for environmental monitoring •Passive • sampling methodologies in various matrices •Recycling • of used drilling fluids and cuttings

2. Yates, K., Pollard P., Davies, I.M, Webster, L., and Moffat, C. (2013) Silicone rubber passive samplers for measuring pore water and exchangeable concentrations of polycyclic aromatic hydrocarbons in sediments. Science of the Total Environment, 463-464: 988-996 3. Yates, K., Pollard P., Davies, I.M, Webster, L., and Moffat, C. (2011) Application of silicone rubber passive samplers to investigate bioaccumulation of PAHs in Nereis virens, Environmental Pollution 159 (12), pp 3351-3356 4. Rhind, S.M., Kyle, C.E., Mackie, C., Yates, K. and Duff, E.I. (2011) Geographic variation in tissue accumulation of endocrine disrupting compounds (EDCs) in grazing sheep, Environmental Pollution, 1519 (2), pp 416-422 5. Yates, K. Davies, I.M, Webster, L., Pollard P., Lawton, L., and Moffat, C. (2007) Passive sampling: Partition coefficients for a silicone rubber reference phase, Journal of Environmental Monitoring, Vol. 9, pp 1116-1121

Page 22

Practice RESEARCH Innovations in pharmacy practice • sustainable models of integrated multidisciplinary care • independent prescribing • pharmaceutical care • interprofessional learning • self-care • technology enhanced practice Medicines use • Medicine effectiveness and safety • specific medicine groups • individual medicines • Medicine processes and procedures Improving nutritional care • working with food suppliers • modification of food products

Prof. Derek Stewart BPharm (hons), MSc, PHd, PGCERT Clinical PracTICE THeme LEader

Professor of Pharmacy Practice, Lead for Practice Research, ResearchGate https://www.researchgate.net/profile/Derek_Stewart2 Orcid Link http://orcid.org/0000-0001-7360-8592 RGU Link http://www.rgu.ac.uk/derek-stewart Prof. Stewart leads the Clinical Practice theme.

organisations and society at local, national and

He has expertise in a wide spectrum of health

international levels. He has an international reputation

services research methodologies and methods.

in the field on non-medical prescribing education,

His research spans very many different

policy, practice and research.

practice research areas, with particular focus on developing, implementing and evaluating models of care, and the safe and effective use of medicines.

He collaborates widely with academics and practitioners across the globe and is currently leading

Email

d.stewart@rgu.ac.uk Telephone

+44 (0) 1224 262432 Research Interest •Development, • implementation and evaluation of non-medical prescribing models of practice; appropriate prescribing in all patients groups, particularly older people

major research programmes in the Middle East and is a key player in a European Commission funded

He has led pharmacy practice research generating

study of inappropriate polypharmacy being led by the

evidence of impact on patients, professionals,

Scottish Government.

1. Alqubaisi M, Tonna A, Strath A, Stewart D. Exploring behavioural determinants relating to health professional reporting of medication errors: a qualitative study using the Theoretical Domains Framework. European Journal of Clinical Pharmacology 2016;72:887895.DOI 10.1007/s00228-016-2054-9 2. McLay JS, Pallivalappila AR, Shetty A, Pande B, Moza Al Hail, Stewart D. ‘Asking the Right Question’. A Comparison of Two Approaches to Gathering Data on ‘Herbals’ Use in Survey Based Studies. PLoS ONE 11(2): e0150140. DOI:10.1371/journal. pone.0150140 3. Al Shemeili S, Klein S, Strath A, Fares S, Stewart D. An exploration of health professionals’ experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. International Journal of Clinical Pharmacy 2016;38:107-118.DOI 10.1007/s11096015-0212-2 4. Tucker R, Stewart D. An exploratory study of the views of community pharmacists on the management of patients with undiagnosed skin problems. International Journal of Pharmacy Practice 2015;23:390-398DOI 10.1111/ijpp.12179 5. Rushworth GF, Diack L, MacRobbie A, Munoz SA, Pfleger S, Stewart D. Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands & Western Isles. Public Health 2015;129:244-251.DOI: 0.1016/j.puhe.2015.01.005

•Patient • safety in general and medication errors specifically •Use, • effectiveness and harm associated with complementary and alternative medicines •Access • to medicines, particularly in remote and rural areas; development of strategies to reduce medication waste •Medicines • adherence, associated behavioural determinants Page 24

Dr. Scott Cunningham BSc (Hons) , PGDip, PHD

Email

s.cunningham@rgu.ac.uk

Senior Lecturer,

Telephone

Orcid Link http://orcid.org/0000-0002-568 RGU Link http://www.rgu.ac.uk/scott-cunningham

+44 (0) 1224 2533

Dr Cunningham is a senior lecturer and group

researcher with research interests spanning many

leader for Clinical Pharmacy and Pharmacy

aspects of pharmacy practice and education.

Practice at the School of Pharmacy and Life Sciences.

Dr Cunningham is involved in researching aspects

Research Interests •Transdisciplinary • education and practice

of pharmacist prescribing including: the training He is a Chair of the Royal Pharmaceutical Society

programme, why some pharmacists choose to train

Faculty Accreditation Panel and has a broad interest in

as prescribers and others do not; how pharmacist

all aspects of quality assurance related to pharmacist

prescribers actually practise; the views of the

development. Dr Cunningham is an external examiner

pharmacist prescribers and their doctor colleagues.

for pharmacy courses and regularly reviews for a

•Pharmacist • prescribing and e-Health implementation •Medication • Adherence in Chronic conditions

number of journals. Dr Cunningham is an active

•Remote • and Rural Healthcare 1. FITZGERALD N, YOUNGSON E, CUNNINGHAM S, WATSON M, STEWART D. Support for community pharmacy-based alcohol interventions: A Scottish general public survey. Public Health. 2015 129(11):1431-8. DOI: 10.1016/j.puhe.2015.07.005 2. HOGAN-MURPHY, D., TONNA, A., STRATH, A. and CUNNINGHAM, S. 2015. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for the prescribing, dispensing and administration of medicines in hospitals: a systematic review. European Journal of Hospital Pharmacy [online], 22(6), 358-365. DOI: 10.1136/ejhpharm-2015-000722 3. STEWART D, GENERALOVA D, CUNNINGHAM S, LESLIE S, RUSHWORTH G, MCIVER L. Healthcare professional and patient views, behaviours and experiences surrounding novel oral anticoagulants (NOACs) for the management of non-valvular atrial fibrillation (AF): a systematic review protocol. PROSPERO 2016: CRD42016003840.

4. MACLURE K, MACLEOD J, FORBES-MCKAY K, CUNNINGHAM S, PAUDYAL V, LYNCH R, STEWART D. A case study investigation into the use of multi-compartment compliance aids in older people resident in very sheltered housing. The Patient: Patient– Centered Outcomes Research. 2016. In press. DOI: 10.1007/s40271-016-0178-8.

Page 25

PROF. Lesley DIack

Email

PhD

h.l.diack@rgu.ac.uk

Professor in Transdisciplinary and Technology Enhanced Learning

Telephone

ResearchGate https://www.researchgate.net/profile/Lesley_Diack Orcid Link http://orcid.org/0000-0002-0037-7794 RGU Link http://www.rgu.ac.uk/dmstaff/diack-lesley/

+44 (0) 1224 262511

Professor Lesley Diack has worked at RGU since

the Centre for the Advancement of Interprofessional

2003, actively working on and researching

Education in Scotland, one of only a few Principal

transdisciplinary and technology enhanced

Fellows of the Higher Education Academy as well as

learning. She was the principal investigator on

a Certified Member of the Association of Learning

a Scottish Government funded Interprofessional

Technology. She has presented widely on education

Education (IPE) project and author of the 2008

and technology topics nationally and internationally

report.

and has published articles on both.

•Technology • Enhanced Learning

She has worked on other funded IPE and pedagogical

Prior to coming to RGU Professor Diack worked as a

projects totalling over £1.2m, including projects with

lecturer and researcher at the University of Aberdeen

Police Scotland, Cancer Link Aberdeen and the North

for a number of years including a Wellcome funded

•Mobile • Apps for Health and social care

(CLAN), Janssen-Cilag, and with collaborators in

project investigating the Aberdeen Typhoid Outbreak

Japan and Qatar. She is the only Honorary Fellow of

of 1964.

Research Interests •Transdisciplinary • education and practice

•Social • media use for health and health professional •Patient • care pathways

1. El-Awaisi, A., Diack, L., Joseph, S., El Hajj, M. (2016) Perspectives of pharmacy students, pharmacy academics and practicing pharmacists on interprofessional education and collaborative practice: a comprehensive systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports DOI: 10.11124/jbisrir-2015-2115

•Innovation •

2. Diack, L., Joseph, S., Garton, F., Haxton, J. (2015) Reflecting on delivering Interprofessional education in practice. Journal of Practice Teaching and Learning 13(2-3) pp32-44.

3. Stewart, D. Al Hail, M., Rouf PVA., Diack, L., [...], Awaisu, A. (2015) Building hospital pharmacy practice research capacity in Qatar: a cross-sectional survey of hospital pharmacists. International Journal of Clinical Pharmacy 37(3):511-21. DOI: 10.1007/s11096015-0087-2 4. Joseph, S., Diack, L. (2015) Playing interprofessional games: reflections on using the Interprofessional Education Game (iPEG).

Journal of Interprofessional Care 29(3): 260-262. DOI: 10.3109/13561820.2014.942839 5. Rushworth, G., Diack, L., Rudd, I., Stewart, D. (2015) General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. International Journal of Clinical Pharmacy 37(1):4-7 DOI: 10.1007/s11096-014-0033-8

Page 26

Dr. Katie MacLure

Email

PhD, MSc, BSc (Hons), DipSysPrac, PgCert

k.m.macLure@rgu.ac.uk

Senior Research Fellow & Lecturer,

Telephone

ResearchGate https://www.researchgate.net/profile/Katie_Maclure Orcid Link http://orcid.org/0000-0003-0686-948X RGU Link http://www.rgu.ac.uk/dmstaff/maclure-katie

+44 (0) 1224 2556 Research Interests

Dr Maclure has expertise in a wide range of

Middle East and a European Commission funded

health services research with a particular

study of inappropriate polypharmacy being led by

interest in ehealth and digital literacy,

the Scottish Government. Closer to home, Katie’s

technology-enabled care, non-medical

research focus in Scotland includes evaluation of

prescribing (NMP), equality of care for

pharmacy dispensing technologies and pharmacist

disadvantaged groups and pharmacy practice.

access to clinical electronic health records.

Dr MacLure works with research partners across the

Dr Maclure also teaches undergraduate and

globe and is currently involved in a major research

postgraduate students qualitative and mixed methods

project around medication error reporting in the

approaches to research.

1. MacLure K, Paudyal V, Stewart D. (2016) Reviewing the literature, how systematic is systematic? International Journal of Clinical Pharmacy (in press) 2. Brown A, MacLure K, Addison B, Pedersen S, Stewart D. Professional body and regulatory organisation guidance on the use of social media for registered healthcare professionals: a systematic review protocol. PROSPERO 2016:CRD42016026877.

•eHealth: • in relation to pharmacy IT strategy, integrated healthcare and digital literacy •Pharmacy • practice and education: non-medical prescribing, consultation skills, pharmacovigilance, technology in pharmacy, role of pharmacy in care of older people •Research • Methods: with a focus on qualitative approaches, research governance, systems practice, systematic reviews

3. Tobaiqy M, Al Humaid S, Stewart D, Omear Alotaibi F, Ahmad Qureshi K, MacLure K, Algharib F, Alsameti A, Alsaqer A and Almeman A (2015) Assessment of Tigecycline Prescription and Patients’ Outcomes at Three Different Hospitals in Saudi Arabia.

Trop J Pharm Res; 14(10): 1919 4. MacLure K, Stewart D (2015) Self-Reported Digital Literacy of the Pharmacy Workforce in North East Scotland. Pharmacy, 3, 182196; doi:10.3390/pharmacy3040182 5. MacLure K, Paudyal V, Stewart D (2015). Making better decisions based on medicines information: how to find and critically appraise relevant literature. ESCP conference (Lisbon, workshop)

Page 27

Dr. Myra MaCkenZie

Email

PhD, HCPC registered dietitian

m.mackenzie3@rgu.ac.uk

Lecturer,

Telephone

Orcid Link http://orcid.org/0000-0002-5680-6287 RGU Link http://www.rgu.ac.uk/dmstaff/mackenzie-myra

+44 (0) 1224 2558

Dr Makenzie has research interests in

Following this, she worked as a clinical dietitian in a

the pedagogy of dietetic education and

variety of different roles, including paediatrics, cystic

in understanding the sociological and

fibrosis and enteral nutrition.

psychological determinants of dietary intake.

Dr Mackenzie is a longstanding member of the British She qualified as a dietitian in 1980, and after 2 years

Dietetic Association, and sits on the Quality Standards

spent in a rotational post at Addenbrookes Hospital,

Committee for dietetic education. She is an HCPC

Cambridge, she undertook a PhD entitled ‘Diet

registered dietitian and a Senior Fellow of the Higher

and Functional Bowel disorders’ supervised jointly

Education Academy.

Research Interests •Nutrition • and hydration in the elderly •Gut • function and diet •Dietetic • pedagogy

by Dr Rodney Burnham at the London Hospital and Professor John Dickerson at the University of Surrey.

•Sociological • and psychological impacts on food choice

1. MACKENZIE, M. NEWMAN, E. and PASIEKA, E. (2016) Exploring social care placements in pre-registration dietetic education.

Submitted to : International Journal of Practice-based Learning in Health and Social Care 2. CAWLEY, R. and MACKENZIE-FRASER, M. (2012) Validation of a food frequency questionnaire for estimating calcium intake in young female adults . Gut; 61:Suppl 2 A86 3. KUMARASAMY,Y., AGUILAR, G.E., GOMARIA,E., MACKENZIE-FRASER, M. (2011). Systematic review of the diagnostic accuracy of monitoring the nutritional status of patients with HIV/AIDS using a validated screening tool. Int. J Evidence based Health care. 10(3): 270 4. RODGERS, A and MACKENZIE-FRASER, M. (2011) Student Nurses’ training and attitudes towards the use of the Malnutrition Universal Screening Tool. Proceedings of the Nutrition Society 70, OCE5, E322 5. TRAVIS, H.E and MACKENZIE-FRASER, M. (2011) The accuracy of MUST assessments by staff in a care home setting. Proceedings of the Nutrition Society 70, 0CE5, E322

Page 28

Dr. Noëlle O’Driscoll

Email

PhD MPharm MRPharmS SFHEA MAPS

n.o-driscoll@rgu.ac.uk

Lecturer in Pharmaceutical Microbiology

Telephone

ResearchGate https://www.researchgate.net/profile/Noelle_ODriscoll Orcid Link http://orcid.org/0000-0003-2146-4202 RGU Link http://www.rgu.ac.uk/staff/noelle-o-driscoll

Dr O’Driscoll’s research areas include the

veterinary pharmacy and the delivery of information

development of novel antimicrobial agents

to under/postgraduate pharmacists on veterinary

for clinical use, assessment of the public

medicines is also a main research theme.

understanding of antibiotic resistance and multi-drug resistant bacteria and most recently the use of mobile apps for educational and healthcare purposes.

Dr O’Driscoll is a Member of The Royal Pharmaceutical Society of Great Britain, the Academy of Pharmaceutical Sciences, the Infection Prevention Society and is a Senior Member of the Higher

Investigation of microbial contamination of

Education Academy. Prior to RGU, Dr O’Driscoll

CleanRooms, operators and products produced

worked extensively in community and hospital

within these areas is another longstanding area

pharmacy both in Scotland and Ireland.

of research.The interaction of pharmacists with

1. Cushnie, T.P.Tim, O’Driscoll, N.H., & Lamb, A.J. Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. Cellular and Molecular Life Sciences 2016.DOI:10.1007/s00018-016-2302-2 2. O’Driscoll, N.H., Labovitiadi, O., and Lamb, A.J. Evaluation of the practice of Veterinary Pharmacy. Currents in Pharmacy Teaching and Learning. Vol. 7 (5), pp. 606-613.DOI:http://dx.doi.org/10.1016/j.cptl.2015.06.017, 2015-09 3. O’Driscoll, N.H., Juwah, C., Labovitiadi, O. and Lamb, A.J. Veterinary Pharmacy within the United Kingdom: Review of current practice and education. Pharmacy Education 2014; 14 (1) pp. 26-30.

4. O’Driscoll, N., Labovitiadi, O., Cushnie, TT., Matthews, KH. and Lamb, AJ. Potassium loss from chlorhexidine-treated bacterial pathogens is time- and concentration-dependent and variable between species. Current Microbiology 2015. 68 (1) pp 6-11.

DOI:http://dx.doi.org/10.1007/s00284-013-0433-3 5. Labovitiadi, O., O’Driscoll, N.H., Lamb, A.J., and Matthews, K.H. Rheological properties of gamma-irradiated antimicrobial wafers and in vitro efficacy against Pseudomonas aeruginosa. International Journal of Pharmaceutics 2013 Sep 10; 453 (2):462-72.

Doi:10.1016/j.ijpharm.2013.06.005.

+44 (0) 1224 262579 Research Interests •Novel • antimicrobials - the development of novel delivery/ formulation methods for existing antibacterial agent •Veterinary • Pharmacy - the prescribing, sale, supply and dispensing of veterinary medicines •Contact • Lenses - the assessment of the hygiene protocols and investigation of the microbial contamination •Aseptic • Suites - assessment and control of microbial contamination of CleanRooms, operators and products •Antibiotic • resistance Page 29

Prof. Alison Strath

Email

FRPharmS

a.strath@rgu.ac.uk

Professor of Community Pharmacy Practice,

Telephone

ResearchGate https://www.researchgate.net/profile/Alison_Strath Orcid Link http://orcid.org/0000-0003-2489-8727 RGU Link http://www.rgu.ac.uk/dmstaff/strath-alison

+44 (0) 1224 2530

Professor Strath has active research interests

at the University of Dundee to develop, evaluate

in pharmacy practice, eHealth and models

and determine the effectiveness of a medical and

of community pharmacy remuneration.

pharmacy student teaching programme aimed at

Other interests include pharmacy education,

enhancing their interprofessional working.

interprofessional learning, pharmaceutical care, prescribing, medicine safety, patient safety, quality improvement and workforce development.

Professor Strath also works part-time with Scottish Government where she is responsible for developing and implementing new community pharmacy services and supporting the ePharmacy

She has attracted funding from NHS Education for

Technology Programme. This role includes policy

Scotland (NES) and the Higher Education Academy

development and implementation. She provided the

(HEA). One programme has led to the establishment

pharmaceutical input to the Scottish Government’s

of a joint academic fellow with the School of Medicine

H1N1 Pandemic Flu response in 2009.

1. Alqubaisi M, Tonna D, Strath A, Stewart D. Quantifying behavioural determinants relating to health professional reporting of medication errors: a cross-sectional survey using the Theoretical Domains Framework. European Journal of Clinical Pharmacology 2016;72:1401–1411. DOI: 10.1007/s00228-016-2124-z 2. Al Shemeili, S., Klein S., Strath A., Stewart, D. An exploration of health professionals’ experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. International Journal of Clinical Pharmacy 2015; 38:107–118. DOI: 10.1007/s11096-0150212-2 3. Hogan-Murphy D., Tonna A., Strath A., Cunningham I.T.S. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for thr prescribing, dispensing and administration of medicines in hospitals: A systematic review.

European Journal of Hospital Pharmacy 2015; 0:1-8. DOI: 10.1136/ejhpharm-2015-000722

Research Interests •Models • of pharmacy practice including eHealth technologies and remuneration models •Quality • improvement •Patient • safety, human factors and simulation in healthcare •Interprofessional • learning in undergraduate and postgraduate education •Healthcare • policy development and implementation

4. MacLure K., Stewart D., Strath A., A systematic review of medical and non-medical practitioners’ views on the impact of ehealth on shared care. European Journal of Hospital Pharmacy 2014; 21:54-62. DOI: 10.1136/ejhpharm-2013-000337 5. Regan K, Harney L, Goodhand K, Strath A and Vosper H. Pharmacy Simulation: A Scottish, Student-Led Perspective with Lessons for the UK and Beyond. Pharmacy 2014; 2:50-64. DOI:10.3390/pharmacy2010050

Page 30

Dr. Antonella Tonna

Email

BPharm (hons), MSc, PHd,MRPharms, MFRPSII

a.tonna@rgu.ac.uk

Lecturer in Clinical Pharmacy

Telephone

ResearchGate https://www.researchgate.net/profile/Antonella_Tonna2 Orcid Link http://orcid.org/0000-tba RGU Link http://www.rgu.ac.uk/antonella-tonna

+44 (0) 1224 262578

Dr Tonna was previously a hospital pharmacist

research. She is also responsabile for facilitates

in Malta for around 10 years and was

workshops and student symposia as part of the

instrumental in setting up numerous services,

annual European Association of Hospital Pharmacists

mainly the ward based clinical pharmacy service

Congress.

in 2002. She moved to the UK and was involved in primary care research in Edinburgh and then worked as a clinical pharmacist at the John Radcliffe Hospital, Oxford.

Dr Tonna graduated with a BPharm (Hons) from the University of Malta in 1994. In 2001 she completed an MSc in Clinical Pharmacy at Robert Gordon University and graduated in 2001, completing a PhD in 2011.

Dr Tonna is a member of the Scottish Antimicrobial Pharmacists’ Association with a key role in developing

1. Alqubaisi M, Tonna A, Strath A, Stewart D. Exploring behavioural determinant relating to health professional reporting of medication errors: a qualitative study using the Theoretical Domains Framework. European Journal of Clinical Pharmacology: 2016: DOI: 10.1007/s00228-016-2054-9 2. Hogan-Murphy D, Tonna A, Strath A, Cunningham S. Healthcare professionals’ perceptions of the facilitators and barriers to implementing electronic systems for the prescribing, dispensing and administration of medicines in hospitals: a systematic review.

European Journal of Hospital Pharmacy 2015: doi:10.1136/ejhpharm-2015-000722 3. Fleming A, Tonna A, O’Connor S, Byrne S, Stewart D. Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys. International Journal of Clinical Pharmacy 2015: DOI 10.1007/s11096-015-0114-3

Research Interests •Antimicrobial • stewardship and the role of the pharmacist in optimising antimicrobial use •Exploring • individuals’ views and perceptions using qualitative research methods •Exploration • of patient and prescribing behaviour relating to antimicrobial prescribing and use •Exploring • patient and carer involvement in delivery of pharmacy education

4. Petrie K., O’Brien C., Bhushan S., Tonna A. Neonatal vancomycin trough level audit using British National Formulary for Children Dosing. Arch Dis Child Fetal Neonatal Ed published online December 17, 2014.

5. Tonna AP, Gould IM, Stewart D. A cross-sectional survey of antimicrobial strategies in UK hospitals. Journal of Clinical Pharmacy and Therapeutics 2014:39: 516-520. DOI: 10.1111/jcpt.12181

Page 31