AOD9604peptide:
Sequence: H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-S er-Cys(1)-Gly-Phe-OH
MolecularFor
mula:
MolecularWe
C78H123N23O23S2
ight: 1815.1g/mol
PubChemCI
D: 71300630
CASNumber:221231-10-3
PeptideGMPManufacturers www.phcoker.com WhatyouneedtoknowaboutAOD9604peptide -ByPhcokercom
Synonyms: 221231-10-3,UNII-7UP768IP4M,7UP768IP4M,EX-A4625
AOD9604Peptideisasyntheticalternativetogrowthhormoneusedtocontro lfatburning.Asagrowthhormonelipolyticpeptidefragment,itcanenhance thebody'smetabolismandacceleratethefatburningprocess.AOD9604wasf irstdiscoveredatMonashUniversityinAustraliawiththeaimofdevelopingan anti-obesitydrug.ThediscoveryandproductionofthepeptideAOD9604has dramaticallyimprovedtheresultsofdietaryrestrictionandexercise.Hereare allthethingsyouneedtoknowaboutAOD9604peptidesandhowitwillben efityourbodyweightcontrol TheStructureOfAOD9604
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WhatIsAOD9604Peptide
?
ObesityisaseriousproblemthataffectscountlesspeoplearoundtheworldR esearchshowsthat25-50%ofpeopleintheUnitedStatesareconsideredover weightorobese.[1][5]Althoughcountlessdietplans,exerciseregimens,andwe ight-lossdrugshavebeenintroducedoverthepastdecadeorsototreatthis problem,nonehaveachievedthedesiredresults.
Originallydevelopedasananti-obesitydrug,AOD9604iscomposedoftheCterminalfragmentofhumangrowthhormonefromaminoacids177-191anda nadditionaltyrosineresidueattheN-terminusofthepeptideAsanorallyava ilablelipopeptidefragmentofhumangrowthhormone,itretainsitslipolyticpr opertiesbutdoesnotstimulatetheproductionofIGF-1.
AOD9604isalsoknownas"AntiObesityDrug9604".Inearlystudies,AOD96 04showedpositiveeffectsinbreakingdownfat.Itisdesignedtotargetstubb ornareasoffatandpromotefatburning.Andthesideeffectsshownarelowe rthanHGH(HumanGrowthHormone)
Manypeoplesufferingfromobesityandresearchexpertsinthefieldofweight losshaveturnedtheirattentiontoAOD9604peptide.TheybuyAOD9604for furtherresearch,includingitsbenefitsforweightloss,use,etc.,hopingtoma kemorebreakthroughsinthefieldofweightloss.Itisdifficulttofindareliab leAOD9604peptidemanufacturersonline.
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TheMechanismofActionOfAOD9604
AOD9604wasoriginallydevelopedforuseasananti-obesitydrug.Asapolyp eptidefragmentofhumanGH,studieshaveshownthatthemainworkingprin cipleoftheAOD9604peptideistoimitatethewaynaturalgrowthhormoner egulatesfatmetabolism.[2][8]
AOD9604powdermainlytargetsfatcellsandcandetectfatcellsinthebody Itbindstoreceptorsonthesefatcells,initiatingasignalingcascadewithinth ecells.Inaddition,itcantriggeraprograminfatcellscalledapoptosis,which candestroyandbreakdownfatcells,leadingtoareductioninbodyfatmass andweightloss.
AOD9604peptidecanalsoindirectlypromotethebody'smetabolism(improvi nginsulinsensitivity,promotingglucosemetabolism,etc)Thisindirecteffectc analsopromoteweightlossandimprovemetaboliccapabilities
ResearchersresearchAOD9604currentfindingsindicatethatAOD9604shows greatpromiseasaweightlossandmetabolicimprovementtreatment.Consid eringtheresearchcostofAOD9604,researchersseekingAOD9604forweight lossresearchuse,prefertobuyitonlineduetotheeasypurchaseprocessand fastdoortodoorshippingservice.
TheBenefitsofAOD9604Powder
AOD9604powderistheactiveingredientofAOD-9604basedpharmaceutical
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weightlossproducts.AOD9064peptidehasreceivedwidespreadattentionas aweightlosspeptide.[4][10]AOD9604powderprovidedbypeptidesupplierP hcokerhasveryimportantbenefitsinpromotingfatlossandweightmanagem ent:
Promoteweightlossandfatloss
AOD9604canstimulatethebreakdownoffatandinhibittheformationofne wfatcells,therebypromotingfatloss.ThisgivesAOD9604peptideitsfat-red ucingeffect.[9][11]
Manageweight
Duetoitsabilitytospecificallytargetfatcellsandpromotefatmetabolism,A OD9604isconsideredtobeoneofthegoodchoicesforweightmanagement andmetabolismpromotion.
Preservemusclemass
AOD9604canreducefat,butunlikeotherweightlossdrugs,AOD9604canr educefatwithoutlosingmuscleItcanhelpretainmusclemass
Enhanceathleticperformance
StudieshaveshownthatAOD9604canpromotefatlosswhileimprovingmusc lemassandendurance,therebyenhancingtheuser'ssportsperformance.
Promotethebody'smetabolism
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Throughthemetabolismoffat,AOD9604willhaveanimpactonthelevelsof insulinandbloodlipids,therebyimprovingthebody'smetabolichealth.Thisi sgoodnewsforpatientswithdiabetesandcardiovasculardisease
Improvebonehealth
Insomeclinicalstudies,AOD9604hasshownthepotentialtorepairbonesan dcartilage,enhancebonehealth,andpreventdiseasessuchasosteoporosis.
Potentialanti-agingeffects
SomestudieshaveshownthatAOD9604peptidehaspotentialanti-agingeffe ctsduetoitsmetabolismandtissuerepaireffects.
Littlesideeffects
Comparedwithotherweightlossmethods,AOD9604hasfewersideeffects.T hisisduetoitsmoretargetedeffectonfatcells,resultinginlesssystemiceff ects.
ThroughthereviewofbestAOD9604peptidebenefitslist,peoplehaveadee perunderstandingofpeptideAOD9604.ItiseasytobuyAOD9604fromphar macies,medicalresearchinstitutions,andpeptidemanufacturers.Becarefulwh enpurchasingAOD9604onlineoroff-line.AOD9604asaninjectablepeptide, itmustbeproducedunderstrictGMPconditionsandfullycomplywithpharm aceuticalgrade.AlthoughitisveryeasytopurchaseAOD9604online,strictrev iewofsuppliersisrequiredtoensurethatthequalityofthepurchasedproduc tsisguaranteedFindoutthebestAOD9604peptidemanufacturerisachallen ge
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AOD9604VsSemaglutide:Differences,Similarities
Whenitcomestoweightlossproducts,Semaglutidehastobementioned.Se maglutideisapprovedbytheFADfordifferentusesunderdifferentbrandnam es,includingOzempic,Wegovy,andRybelsus.
TheUSFood&DrugAdministrationhasrecentlygrantedHumanGRASstatus toAOD9604,asubstanceincludedintheGenerallyRecognizedAsSafe(GRA S)program.Thisclassificationassuresthatwhenusedaccordingtoitsintended purpose,asoutlinedintheFederalFood,Drug,andCosmeticAct,AOD9604 isdeemedsafeforconsumptionasafoodadditive.
AOD9604injectionsarenotablysafe,withnodocumentedhealthrisksassociat edThismakesthemapreferableoptionoverconventionalhormone-basedwei ghtlosstreatments.
AsSemaglutideandAOD9604areverypopularweightlosspeptidesinthew eightlossmarket,whatarethedifferencesandsimilaritiesbetweenthem?Let’ stakealook.
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Inordertohaveadeeperunderstandingthedifferencesandsimilaritiesbetwe enSemaglutideandAOD9604petpide,researchersbuythemfromsomefamo uspeptidemanufacturerslikePhcokertodocomparisontesting.Ifyouareint erestedinweightlosspeptidesresearch,contactphcokerformoreinformation isagoodchoice.
WhatAreTheClinicalTrialsOnAOD9604?
TheclinicalresearchofAOD9604mainlyfocusesonfatreduction.[3][12]Thef ollowingaresomekeypointsabouttheclinicalresearchofAOD9604peptide:
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1.TheweightlosseffectofAOD9604:Earlyclinicalstudiesweremainlyfocuse dontheeffectofAOD9604onfatlossandbodymetabolism.A2004study showedthatsubjectswhotookAOD9604experiencedadecreaseinbodyfat
2.MetaboliceffectsofAOD9604:Astudypublishedin2010investigatedthee ffectofAOD9604onglucosemetabolism.ThisstudyshowedthatAOD9604 powdercanimproveinsulinsensitivityandglucosetolerance,whichisimportan tforthebody.Metabolichealthplaysaveryimportantrole.
3.SafetyofAOD9604:Astudypublishedinthe"JournalofClinicalEndocrinol ogyandMetabolism"in2007showedthatAOD9604wassafeandwell-tolerat ed,anddidnotshowsignificantgoodresultsinthestudy
4.FutureresearchmethodsofAOD9604:Althoughexistingclinicalstudieshav eachievedobjectiveprospectsforthebenefitsofAOD9604,morelong-term experimentalstudiesareneededtoevaluateandanalyzethevariousbenefitsa ndrisksofthispeptide..
ComparetoAOD9604finishedvialform,theAOD9604rawpowderformist hecommonuseformforresearchuseResearcherscanuseAOD9604powder tomakeintodifferentformslikeinjectionaccordingtotheresearchpurpose.I nanotherhand,AOD9604powderisrelativelyeasiertobuy,asitdonotreq uiretheprescriptionandeasytobuyonline.Theimportantistobuyfromgo odpeptideAOD9604manufacturers.
TheSideEffectsOfAOD9604Peptide
AOD9604isapeptidefragmentderivedfromtheGHmolecule.[6][7][13]Altho
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ughmanystudieshaveshownthatthispeptideissafe,youshouldalsobeaw areofthepossiblesideeffectsbeforeusingthisdrug:
Headache
Nausea
Rednessandswellingattheinjectionsite,etc.
Dizziness
Insomnia
Cough
Nasopharyngitis
Palpitations
AOD9604,likeanyotherdrug,cancausesideeffectswhenmixedwithother medications.Youshouldseektheadviceofyourhealthcareproviderwhentre atingwithAOD9604.BuyhighqualityAOD9604peptideismoreguaranteed.
AOD9604ForSale丨AOD9604PeptideSupplier
AOD9604isanorallyactivelipolyticpeptidefragmentofhumangrowthhorm onethatisgenerallybelievedtopromoteweightlossbyenhancingfatmetabo lism.
DuetothebenefitsshownbyAOD9604peptide,moreandmoreresearchers arestudyingthispeptidetoexploremorepotentialbenefitsofAOD9604Curr entlyyoucanseemanypeptidemanufacturerssellingAOD9604onlineButw henbuyingAOD9604powder,youneedtofindareliableandtrustworthyma nufacturer.
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Phcokerisaprofessionalpeptidemanufacturerthatcanprovidehigh-qualityA OD9604rawpowderandvialsWhetheryouarebuyingAOD9604insmallqu antitiesorinbulk,PhcokerwillprovideyouwithpreferentialpricesIfyouwan ttobuyAOD9604online,Phcokercommaybeagoodchoiceforyou
Manufacturers/Factory
AOD9604isadrugthatcanstimulatelipolysisandinhibitlipogenesis,andthi sdrughasbeenapprovedbytheFDA.AOD9604fat-burningpeptidewasorig inallydevelopedasananti-obesitydrug.AsamodifiedversionofHGH,itcan stimulatethebody'spituitaryglandafterinjection,whichwillacceleratethebo dy'smetabolismandincreaseweightlossSomehumanstudieshaveshownth atalthoughAOD9604hasfat-breakingproperties,itdoesnotstimulatethepr oductionofIGF-1atthesametime.Ifyouaretroubledbystubbornfat,AOD 9604weightlosspeptidemaybeabletosolveyourproblem.
AsthebestAOD9604peptidemanufacturer,Phcokerisnotonlysupplythep eptideAOD9604inpowderformbutprovidethecustomizedstandardeasyus evialform
YoucanbuythebestpriceAOD9604andbestqualitypeptidefromthisprofe ssionalpeptidemanufacturer.Asasuper“weightlossmagicdrug”,Semaglutid epeptidegettingmoreandmorepopular.Whentyping"weightlossdrug"on themajorsocialplatforms,whatcomesintoviewisthepursuitof"thinness"
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and"beauty"bymanypeople.Theymaysharehowtobuyweightlossdrugo nlineortheweightlossdruguseeffects.Oneofthemostfrequentlymention edweightlossdrugsisundoubtedlysemaglutide
F&QAboutSemaglutide
WhatisAOD9604?
AOD9604isafat-burningweight-losspeptidethatstimulateslipolysisandinhibits theformationofnewfatcells.
DoesAOD9604reallywork?
Accordingtotheresearchresultsofclinicaltrials,AOD9604hasaverysignificant effectinpromotingfatburningandimprovingthebody'smetabolism.
DoesAOD9604haveothernicknames?
AOD9604isalsoknownaslipotropinandTyr-hGHfragment. WhenisthebesttimetotakeAOD9604?
IfyouwanttogetthebestresultsfromAOD9604,youshouldpreferablyuseitonan emptystomachThebesttimetouseitisinthemorning,butyoucanalsouseit
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30-45minutesafterthelastmeal
InwhatenvironmentshouldAOD9604bestored?
AOD9604shouldbekeptintherefrigeratoratatemperaturebetween25-46℉. Remembernottofreezeit.
IsAOD9604safe?
NumerousstudieshavesuccessfullyshownthatuseofAOD9604issafeandthat AOD9604iswelltolerated.
HowlongwillittakeformetoseetheeffectsofAOD9604?
Sinceeveryone'sphysicalconditionisdifferent,thetimeittakestoseetheresultsof AOD9604isalsodifferent.Butgenerallyspeaking,itusuallytakesatleast12weeks toseethesignificanteffectsofAOD9604onyourbody.
HowtoinjectAOD9604correctly?
ThefollowingisthecorrectwaytoinjectAOD9604:
UseasyringetodrawtherequiredAOD9604solution
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Itisbesttogivesubcutaneousinjectionsinareasoftheabdomenwithahigher concentrationoffat
Makesuretheentireprocessiscleantoavoidinfection
WillAOD9604increaseyourappetite?
No,AOD9604willnotonlynotincreaseyourappetite,butitwillhelpusersincrease theirsatietyandreducefoodintake,thuspromotingweightloss.
IsAOD9604nasalsprayeffective?
ThecommonwayofadministrationofAOD9604issubcutaneousinjection,andthe effectivenessofitsnasalsprayformrequiresmoreexperimentsIfyouwouldliketo usethisformofAOD9604,talktoyourhealthcareprofessional.
ReferencesCitations:
[1]Heffernan,M.;Summers,R.J.;Thorburn,A.;Ogru,E.;Gianello,R.;Jiang,W.J.;Ng,F. M.(December2001)."TheeffectsofhumanGHanditslipolyticfragment(AOD9604) onlipidmetabolismfollowingchronictreatmentinobesemiceandbeta(3)-AR knock-outmice"Endocrinology142(12):5182–5189doi:101210/endo142128522
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ISSN0013-7227PMID11713213
[2]Stier,Heike;Vos,Evert;Kenley,David(2013-04-23)."SafetyandTolerabilityofthe HexadecapeptideAOD9604inHumans".JournalofEndocrinologyandMetabolism. 3(1–2):7–15.doi:10.4021/jem157w.ISSN1923-287X.
[3]Valentino,MichaelA.;Lin,JieruE.;Waldman,ScottA.(June2010)."Centraland PeripheralMolecularTargetsforAnti-ObesityPharmacotherapy"Clinical PharmacologyandTherapeutics.87(6):652–662.doi:10.1038/clpt.2010.57.ISSN
0009-9236.PMC3136748.PMID20445536.
[4]HeffernanM,SummersRJ,ThorburnA,OgruE,GianelloR,JiangWJ,NgFM.”The effectsofhumanGHanditslipolyticfragment(AOD9604)onlipidmetabolism followingchronictreatmentinobesemiceandbeta(3)-ARknock-out mice”.Endocrinology.2001Dec;142(12):5182-9.doi: 10.1210/endo.142.12.8522.PMID:11713213.
[5]HeffernanMA,ThorburnAW,FamB,SummersR,Conway-CampbellB,WatersMJ, NgFM.”Increaseoffatoxidationandweightlossinobesemicecausedbychronic treatmentwithhumangrowthhormoneoramodifiedC-terminalfragment”IntJ ObesRelatMetabDisord.2001Oct;25(10):1442-9.doi:10.1038/sj.ijo.0801740..PMID: 11673763
[6]HeffernanMA,JiangWJ,ThorburnAW,NgFM.”Effectsoforaladministrationofa
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syntheticfragmentofhumangrowthhormoneonlipidmetabolism”AmJPhysiol EndocrinolMetab.2000Sep;279(3):E501-7.doi:
10.1152/ajpendo.2000.279.3.E501.PMID:10950816.
[7]NgFM,JiangWJ,GianelloR,PittS,RoupasP.”Molecularandcellularactionsofa structuraldomainofhumangrowthhormone(AOD9401)onlipidmetabolismin Zuckerfattyrats”JMolEndocrinol2000Dec;25(3):287-98doi: 10.1677/jme.0.0250287.PMID:11116208.
[8]LanginD.A”diposetissuelipolysisasametabolicpathwaytodefine pharmacologicalstrategiesagainstobesityandthemetabolic syndrome”.PharmacolRes.2006Jun;53(6):482-91.doi:10.1016/j.phrs.2006.03.009.
Epub2006Mar27PMID:16644234
[9]IughettiL,ChinaM,BerriR,PredieriB.”Pharmacologicaltreatmentofobesityin childrenandadolescents:presentandfuture.”JObes.2011;2011:928165.doi: 10.1155/2011/928165.Epub2010Dec15.PMID:21197151.
[10]MisraM.”Obesitypharmacotherapy:currentperspectivesandfuture directions”CurrCardiolRev2013Feb1;9(1):33-54doi: 10.2174/157340313805076322.PMID:23092275.
[11]IsidroML,CordidoF.”ApprovedandOff-LabelUsesofObesityMedications,and PotentialNewPharmacologicTreatmentOptions.”Pharmaceuticals(Basel).2010Jan
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www.phcoker.com
12;3(1):125-145doi:103390/ph3010125PMID:27713245
[12]HabibullahMM,MohanS,SyedNK,MakeenHA,JamalQMS,AlothaidH,Bantun F,AlhazmiA,HakamyA,KaabiYA,SamlanG,LohaniM,ThangavelN,Al-Kasim MA.”HumanGrowthHormoneFragment176-191PeptideEnhancestheToxicityof Doxorubicin-LoadedChitosanNanoparticlesAgainstMCF-7BreastCancer Cells”DrugDesDevelTher2022Jun27;16:1963-1974doi:102147/DDDTS367586 eCollection2022.PMID:35783198.
[13]HarpurCM,WestAC,LePageMA,LamM,HodgesC,OseghaleO,GearingAJ, TateMD.”Naturallyderivedcytokinepeptideslimitvirusreplicationandsevere diseaseduringinfluenzaAvirusinfection.”ClinTranslImmunology.2023Mar 23;12(3):e1443doi:101002/cti21443eCollection2023PMID:36969366
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