HORMONE THERAPY
IN BREAST CANCER
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t Content List PRESENTATION What is Hormone Therapy? 01 02 Types of Hormone Therapy Thank you Contact us 03 04 05 How it Works in Breast Cancer Treatment
What is Hormone Therapy
Breast cancer is a type of cancer that develops in breast cells. It is the second most common cancer in women worldwide, and the leading cause of cancer death among women. Hormone therapy is a type of cancer treatment that works by blocking or reducing the levels of hormones in the body. In this blog post, we will explore what it is, how it works in breast cancer treatment, the precautions you should take, and how to consult a doctor.
01
How it Works in Breast Cancer Treatment
Hormone therapy is most commonly used to treat breast cancer that is hormone receptor-positive. This means that the cancer cells have receptors that can bind to hormones such as estrogen and progesterone, which can stimulate the growth of cancer cells. It works by either blocking the production of these hormones or blocking the receptors on cancer cells, preventing the hormones from binding to them.
04
Types
• Selective estrogen receptor modulators (SERMs): These drugs work by blocking the estrogen receptors on cancer cells, preventing estrogen from binding to them. Examples of SERMs include tamoxifen and raloxifene.
• Aromatase inhibitors: These drugs work by blocking the enzyme aromatase, which converts androgens into estrogen. By reducing the levels of estrogen in the body, they can slow or stop the growth of hormone receptor-positive breast cancer cells. Examples of aromatase inhibitors include anastrozole, letrozole, and exemestane.
• Gonadotropin-releasing hormone (GnRH) agonists: These drugs work by reducing the levels of estrogen and progesterone in the body by suppressing the production of gonadotropins, which are hormones that stimulate the ovaries to produce estrogen and progesterone. Examples of GnRH agonists include goserelin and leuprolide.
• Estrogen receptor down regulators: These drugs work by blocking the estrogen receptors on cancer cells and reducing their numbers. Examples of estrogen receptor down regulators include fulvestrant.
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