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HandbookofHuman-MachineSystems

IEEEPress

445HoesLane Piscataway,NJ08854

IEEEPressEditorialBoard

SarahSpurgeon, EditorinChief

JónAtliBenediktsson

AnjanBose

JamesDuncan

AminMoeness

DesineniSubbaramNaidu

BehzadRazavi

JimLyke

HaiLi

BrianJohnson

JeffreyReed

DiomidisSpinellis

AdamDrobot

TomRobertazzi

AhmetMuratTekalp

HandbookofHuman-MachineSystems

Editedby

GiancarloFortino UniversityofCalabria Italy

DavidKaber UniversityofFlorida USA

AndreasNürnberger

Otto-von-Guericke-UniversitätMagdeburg Germany

DavidMendonça

MITRECorporation USA

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Contents

EditorsBiography xxi

ListofContributors xxiii

Preface xxxiii

1Introduction 1 GiancarloFortino,DavidKaber,AndreasNürnberger,andDavidMendonça

1.1BookRationale 1

1.2ChaptersOverview 2 Acknowledgments 8 References 8

2Brain–ComputerInterfaces:RecentAdvances,Challenges,andFuture Directions 11 TiagoH.Falk,ChristophGuger,andIvanVolosyak

2.1Introduction 11

2.2Background 12

2.2.1Active/ReactiveBCIs 13

2.2.2PassiveBCIs 14

2.2.3HybridBCIs 15

2.3RecentAdvancesandApplications 15

2.3.1Active/ReactiveBCIs 15

2.3.2PassiveBCIs 16

2.3.3HybridBCIs 16

2.4FutureResearchChallenges 16

2.4.1CurrentResearchIssues 17

2.4.2FutureResearchDirections 17

2.5Conclusions 18 References 18

3Brain–ComputerInterfacesforAffectiveNeurofeedbackApplications 23 LucasR.TrambaiolliandTiagoH.Falk

3.1Introduction 23

3.2Background 23

3.3State-of-the-Art 24

3.3.1DepressiveDisorder 25

3.3.2PosttraumaticStressDisorder,PTSD 26

3.4FutureResearchChallenges 27

3.4.1OpenChallenges 27

3.4.2FutureDirections 28

3.5Conclusion 28

References 29

4PediatricBrain–ComputerInterfaces:AnUnmetNeed 35

EliKinney-Lang,EricaD.Floreani,NiloufaralsadatHashemi,DionKelly,StefanieS.Bradley, ChristineHorner,BrianIrvine,ZeannaJadavji,DanetteRowley,IlyasSadybekov,SiLong JennyTou,EphremZewdie,TomChau,andAdamKirton

4.1Introduction 35

4.1.1Motivation 36

4.2Background 36

4.2.1ComponentsofaBCI 36

4.2.1.1SignalAcquisition 36

4.2.1.2SignalProcessing 36

4.2.1.3Feedback 36

4.2.1.4Paradigms 37

4.2.2BrainAnatomyandPhysiology 37

4.2.3DevelopmentalNeurophysiology 38

4.2.4ClinicalTranslationofBCI 38

4.2.4.1AssistiveTechnology(AT) 38

4.2.4.2ClinicalAssessment 39

4.3CurrentBodyofKnowledge 39

4.4ConsiderationsforPediatricBCI 40

4.4.1DevelopmentalImpactonEEG-basedBCI 40

4.4.2HardwareforPediatricBCI 41

4.4.3SignalProcessingforPediatricBCI 41

4.4.3.1FeatureExtraction,SelectionandClassification 42

4.4.3.2EmergingTechniques 42

4.4.4DesigningExperimentsforPediatricBCI 43

4.4.5MeaningfulApplicationsforPediatricBCI 43

4.4.6ClinicalTranslationofPediatricBCI 44

4.5Conclusions 44 References 45

5Brain–ComputerInterface-basedPredator–PreyDroneInteractions 49 AbdelkaderNasreddineBelkacemandAbderrahmaneLakas

5.1Introduction 49

5.2RelatedWork 50

5.3Predator–PreyDroneInteraction 51

5.4ConclusionandFutureChallenges 57 References 58

6LevelsofCooperationinHuman–MachineSystems:AHuman–BCI–Robot Example 61 Marie-PierrePacaux-Lemoine,LydiaHabib,andTomCarlson

6.1Introduction 61

6.2LevelsofCooperation 61

6.3ApplicationtotheControlofaRobotbyThought 63

6.3.1DesigningtheSystem 64

6.3.2ExperimentsandResults 66

6.4ResultsfromtheMethodologicalPointofView 67

6.5ConclusionandPerspectives 68 References 69

7Human–MachineSocialSystems:TestandValidationviaMilitary UseCases 71

CharleneK.Stokes,MonikaLohani,ArwenH.DeCostanza,andElliotLoh

7.1Introduction 71

7.2BackgroundSummary:FromToolstoTeammates 72

7.2.1TwoSidesoftheEquation 72

7.2.2MovingBeyondtheCognitiveRevolution 73

7.2.2.1ARediscoveryoftheUnconscious 74

7.3FutureResearchDirections 75

7.3.1Machine:FunctionalDesigns 75

7.3.2Human:GroundTruth 76

7.3.2.1PhysiologicalComputing 76

7.3.3Context:TyingItAllTogether 77

7.3.3.1TrainingandTeamModels 77

7.4Conclusion 79 References 79

8TheRoleofMultimodalDataforModelingCommunicationinArtificial SocialAgents 83

StephanieGrossandBrigitteKrenn

8.1Introduction 83

8.2Background 84

8.2.1Context 84

8.2.2BasicDefinitions 84

8.3RelatedWork 84

8.3.1HHIData 85

8.3.2HRIData 85

8.3.2.1JointAttentionandRobotTurn-TakingCapabilities 85

8.3.3PublicAvailabilityoftheData 87

8.4DatasetsandResultingImplications 87

8.4.1HumanCommunicativeSignals 87

8.4.1.1ExperimentalSetup 87

8.4.1.2DataAnalysisandResults 88

8.4.2HumansReactingtoRobotSignals 89

8.4.2.1ComparingDifferentRoboticTurn-GivingSignals 89

8.4.2.2ComparingDifferentTransparencyMechanisms 90

8.5Conclusions 91

8.6FutureResearchChallenges 91 References 91

9ModelingInteractionsHappeninginPeople-DrivenCollaborative Processes 95 MaximilianoCanche,SergioF.Ochoa,DanielPerovich,andRodrigoSantos

9.1Introduction 95

9.2Background 97

9.3State-of-the-ArtinInteractionModelingLanguagesandNotations 98

9.3.1VisualLanguagesandNotations 99

9.3.2ComparisonofInteractionModelingLanguagesandNotations 100

9.4ChallengesandFutureResearchDirections 101 References 102

10TransparentCommunicationsforHuman–MachineTeaming 105

JessieY.C.Chen

10.1Introduction 105

10.2DefinitionsandFrameworks 105

10.3ImplementationofTransparentHuman–MachineInterfacesinIntelligent Systems 106

10.3.1Human–RobotInteraction 106

10.3.2MultiagentSystemsandHuman–SwarmInteraction 108

10.3.3Automated/AutonomousDriving 109

10.3.4ExplainableAI-BasedSystems 109

10.3.5GuidelinesandAssessmentMethods 109

10.4FutureResearchDirections 110 References 111

11ConversationalHuman–MachineInterfaces 115 MaríaJesúsRodríguez-Sánchez,KawtarBenghazi,DavidGriol,andZoraidaCallejas

11.1Introduction 115

11.2Background 115

11.2.1HistoryoftheDevelopmentoftheField 116

11.2.2BasicDefinitions 117

11.3State-of-the-Art 117

11.3.1DiscussionoftheMostImportantScientific/TechnicalContributions 117

11.3.2ComparisonTable 119

11.4FutureResearchChallenges 121

11.4.1CurrentResearchIssues 121

11.4.2FutureResearchDirectionsDealingwiththeCurrentIssues 121 References 122

12Interaction-CenteredDesign:AnEnduringStrategyandMethodologyfor SociotechnicalSystems 125 MingHou,ScottFang,WenbiWang,andPhilipS.E.Farrell

12.1Introduction 125

12.2EvolutionofHMSDesignStrategy 126

12.2.1AHMSTechnology:IntelligentAdaptiveSystem 126

12.2.2EvolutionofIASDesignStrategy 128

12.3State-of-the-Art:Interaction-CenteredDesign 130

12.3.1AGenericAgent-basedICDFramework 130

12.3.2IMPACTS:AnHuman–MachineTeamingTrustModel 132

12.3.3ICDRoadmapforIASDesignandDevelopment 133

12.3.4ICDValidation,Adoption,andContributions 134

12.4IASDesignChallengesandFutureWork 135

12.4.1ChallengesofHMSTechnology 136

12.4.2FutureWorkinIASDesignandValidation 136 References 137

13Human–MachineComputing:Paradigm,Challenges,andPractices 141 ZhiwenYu,QingyangLi,andBinGuo

13.1Introduction 141

13.2Background 142

13.2.1HistoryoftheDevelopment 142

13.2.2BasicDefinitions 143

13.3StateoftheArt 144

13.3.1TechnicalContributions 144

13.3.2ComparisonTable 148

13.4FutureResearchChallenges 150

13.4.1CurrentResearchIssues 150

13.4.2FutureResearchDirections 151 References 152

14CompanionTechnology 155 AndreasWendemuth

14.1Introduction 155

14.2Background 155

14.2.1History 156

14.2.2BasicDefinitions 157

14.3State-of-the-Art 158

14.3.1DiscussionoftheMostImportantScientific/TechnicalContributions 159

14.4FutureResearchChallenges 159

14.4.1CurrentResearchIssues 159

14.4.2FutureResearchDirectionsDealingwiththeCurrentIssues 160 References 161

15ASurveyonRollator-TypeMobilityAssistanceRobots 165 MiladGeravand,ChristianWerner,KlausHauer,andAngelikaPeer

15.1Introduction 165

15.2MobilityAssistancePlatforms 165

15.2.1Actuation 166

15.2.2Kinematics 166

15.2.2.1LocomotionSupport 166

15.2.2.2STSSupport 166

15.2.3Sensors 168

15.2.4Human–MachineInterfaces 168

15.3Functionalities 168

x Contents

15.3.1STSAssistance 169

15.3.2WalkingAssistance 169

15.3.2.1ManeuverabilityImprovement 169

15.3.2.2GravityCompensation 170

15.3.2.3ObstacleAvoidance 170

15.3.2.4FallsRiskPredictionandFallPrevention 170

15.3.3LocalizationandNavigation 170

15.3.3.1MapBuildingandLocalization 171

15.3.3.2PathPlanning 171

15.3.3.3AssistedLocalization 171

15.3.3.4AssistedNavigation 171

15.3.4FurtherFunctionalities 171

15.3.4.1ReminderSystems 171

15.3.4.2HealthMonitoring 171

15.3.4.3Communication,Information,Entertainment,andTraining 172

15.4Conclusion 172 References 173

16AWearableAffectiveRobot 181

JiaLiu,JinfengXu,MinChen,andIztokHumar

16.1Introduction 181

16.2ArchitectureDesignandCharacteristics 183

16.2.1ArchitectureofaWearableAffectiveRobot 183

16.2.2CharacteristicsofaWearableAffectiveRobot 184

16.3DesignoftheWearable,AffectiveRobot’sHardware 185

16.3.1AIWACBoxHardwareDesign 185

16.3.2HardwareDesignoftheEEGAcquisition 185

16.3.3AIWACSmartTactileDevice 185

16.3.4PrototypeoftheWearableAffectiveRobot 186

16.4AlgorithmfortheWearableAffectiveRobot 186

16.4.1AlgorithmforAffectiveRecognition 186

16.4.2User-BehaviorPerceptionbasedonaBrain-WearableDevice 186

16.5LifeModelingoftheWearableAffectiveRobot 187

16.5.1DataSetLabelingandProcessing 188

16.5.2MultidimensionalDataIntegration 188

16.5.3ModelingofAssociatedScenarios 188

16.6ChallengesandProspects 189

16.6.1ResearchChallengesoftheWearableAffectiveRobot 189

16.6.2ApplicationScenariosfortheWearableAffectiveRobot 189

16.7Conclusions 190

References 190

17VisualHuman–ComputerInteractionsforIntelligentVehicles 193 XumengWang,WeiChen,andFei-YueWang

17.1Introduction 193

17.2Background 193

17.3State-of-the-Art 194

17.3.1VHCIinVehicles 194

17.3.1.1InformationFeedbackfromIntelligentVehicles 195

17.3.1.2Human-GuidedDriving 195

17.3.2VHCIAmongVehicles 195

17.3.3VHCIBeyondVehicles 195

17.4FutureResearchChallenges 196

17.4.1VHCIforIntelligentVehicles 196

17.4.1.1VehicleDevelopment 196

17.4.1.2VehicleManufacture 197

17.4.1.3PreferenceRecording 197

17.4.1.4VehicleUsage 197

17.4.2VHCIforIntelligentTransportationSystems 198

17.4.2.1ParallelWorld 198

17.4.2.2TheFrameworkofIntelligentTransportationSystems 198 References 199

18IntelligentCollaborationBetweenHumansandRobots 203 AndreaMariaZanchettin

18.1Introduction 203

18.2Background 203

18.2.1Context 203

18.2.2BasicDefinitions 204

18.3RelatedWork 205

18.4ValidationCases 206

18.4.1ASimpleVerificationScenario 207

18.4.2ActivityRecognitionBasedonSemanticHand-ObjectInteraction 208

18.5Conclusions 210

18.6FutureResearchChallenges 210 References 210

19ToBeTrustworthyandToTrust:TheNewFrontierofIntelligent Systems 213 RinoFalcone,AlessandroSapienza,FilippoCantucci,andCristianoCastelfranchi

19.1Introduction 213

19.2Background 214

19.3BasicDefinitions 214

19.4State-of-the-Art 215

19.4.1TrustinDifferentDomains 215

19.4.2SelectedArticles 215

19.4.3DifferencesintheUseofTrust 216

19.4.4ApproachestoModelTrust 217

19.4.5SourcesofTrust 218

19.4.6DifferentComputationalModelsofTrust 218

19.5FutureResearchChallenges 220 References 221

20DecodingHumans’andVirtualAgents’EmotionalExpressions 225 TerryAmorese,GennaroCordasco,MarialuciaCuciniello,OlgaShevaleva,StefanoMarrone, CarlVogel,andAnnaEsposito

20.1Introduction 225

20.2RelatedWork 226

20.3MaterialsandMethodology 227

20.3.1Participants 227

20.3.2Stimuli 228

20.3.3ToolsandProcedures 228

20.4DescriptiveStatistics 229

20.5DataAnalysisandResults 230

20.5.1ComparisonSyntheticvs.NaturalisticExperiment 234

20.6DiscussionandConclusions 235

Acknowledgment 238 References 238

21IntelligentComputationalEdge:FromPervasiveComputingandInternetof ThingstoComputingContinuum 241 RadmilaJuric

21.1Introduction 241

21.2TheJourneyofPervasiveComputing 242

21.3ThePoweroftheIoT 243

21.3.1InherentProblemswiththeIoT 244

21.4IoT:TheJourneyfromCloudtoEdge 245

21.5TowardIntelligentComputationalEdge 246

21.6IsComputingContinuumtheAnswer? 247

21.7DoWeHaveMoreQuestionsthanAnswers? 248

21.8WhatWouldourVisionBe? 249 References 251

22ImplementingContextAwarenessinAutonomousVehicles 257 FedericoFaruffini,AlessandroCorrea-Victorino,andMarie-HélèneAbel

22.1Introduction 257

22.2Background 258

22.2.1Ontologies 258

22.2.2AutonomousDriving 258

22.2.3BasicDefinitions 259

22.3RelatedWorks 260

22.4ImplementationandTests 261

22.4.1ImplementingtheContextofNavigation 261

22.4.2ControlLoopRule 262

22.4.3Simulations 263

22.5Conclusions 264

22.6FutureResearchChallenges 264 References 264

23TheAugmentedWorkforce:ASystematicReviewofOperatorAssistance Systems 267

ElisaRoth,MircoMoencks,andThomasBohné

23.1Introduction 267

23.2Background 268

23.2.1Definitions 268

23.3StateoftheArt 269

23.3.1EmpiricalConsiderations 270

23.3.1.1ApplicationAreas 270

23.3.2AssistanceCapabilities 270

23.3.2.1TaskGuidance 271

23.3.2.2KnowledgeManagement 271

23.3.2.3Monitoring 273

23.3.2.4Communication 273

23.3.2.5Decision-Making 273

23.3.3Meta-capabilities 274

23.3.3.1ConfigurationFlexibility 274

23.3.3.2Interoperability 274

23.3.3.3ContentAuthoring 274

23.3.3.4Initiation 274

23.3.3.5Hardware 275

23.3.3.6UserInterfaces 275

23.4FutureResearchDirections 275

23.4.1EmpiricalEvidence 275

23.4.2CollaborativeResearch 277

23.4.3SystemicApproaches 277

23.4.4Technology-MediatedLearning 277

23.5Conclusion 277 References 278

24CognitivePerformanceModeling 281

MaryamZahabiandJunhoPark

24.1Introduction 281

24.2Background 281

24.3State-of-the-Art 282

24.4CurrentResearchIssues 286

24.5FutureResearchDirectionsDealingwiththeCurrentIssues 286 References 287

25AdvancedDriverAssistanceSystems:TransparencyandDriverPerformance Effects 291 YulinDengandDavidB.Kaber

25.1Introduction 291

25.2Background 292

25.2.1Context 292

25.2.2BasicDefinition 292

25.3RelatedWork 293

25.4Method 294

25.4.1Apparatus 295

25.4.2Participants 296

25.4.3ExperimentDesign 296

25.4.4Tasks 297

25.4.5DependentVariables 297

25.4.5.1HazardNegotiationPerformance 297

25.4.5.2VehicleControlPerformance 298

25.4.6Procedure 298

25.5Results 299

25.5.1HazardReactionPerformance 299

25.5.2PosthazardManualDrivingPerformance 299

25.5.3PosttestingUsabilityQuestionnaire 301

25.6Discussion 302

25.7Conclusion 303

25.8FutureResearch 304 References 304

26RGB-DBasedHumanActionRecognition:FromHandcraftedtoDeep Learning 307 BangliLiuandHonghaiLiu

26.1Introduction 307

26.2RGB-DSensorsand3DData 307

26.3HumanActionRecognitionviaHandcraftedMethods 308

26.3.1Skeleton-BasedMethods 308

26.3.2Depth-BasedMethods 309

26.3.3HybridFeature-BasedMethods 309

26.4HumanActionRecognitionviaDeepLearningMethods 310

26.4.1CNN-BasedMethods 310

26.4.2RNN-BasedMethods 311

26.4.3GCN-BasedMethods 313

26.5Discussion 314

26.6RGB-DDatasets 314

26.7ConclusionandFutureDirections 315 References 316

27HybridIntelligence:AugmentingEmployees’Decision-MakingwithAI-Based Applications 321 InaHeine,ThomasHellebrandt,LouisHuebser,andMarcosPadrón

27.1Introduction 321

27.2Background 321

27.2.1Context 321

27.2.2BasicDefinitions 322

27.3RelatedWork 323

27.4TechnicalPartoftheChapter 324

27.4.1DescriptionoftheUseCase 324

27.4.1.1BusinessModel 324

27.4.1.2Process 324

27.4.1.3UseCaseObjectives 325

27.4.2DescriptionoftheEnvisionedSolution 325

27.4.3DevelopmentApproachofAIApplication 326

27.4.3.1DevelopmentProcess 326

27.4.3.2ProcessAnalysisandTimeStudy 326

27.4.3.3DevelopmentandDeploymentData 327

27.4.3.4SystemTestingandDeployment 327

27.4.3.5DevelopmentInfrastructureandDevelopmentCostMonitoring 327

27.5Conclusions 330

27.6FutureResearchChallenges 330 References 330

28HumanFactorsinDriving 333

BirsenDonmez,DengboHe,andHollandM.Vasquez

28.1Introduction 333

28.2ResearchMethodologies 334

28.3In-VehicleElectronicDevices 335

28.3.1Distraction 335

28.3.2InteractionModality 336

28.3.2.1VisualandManualModalities 336

28.3.2.2AuditoryandVocalModalities 337

28.3.2.3HapticModality 338

28.3.3WearableDevices 338

28.4VehicleAutomation 339

28.4.1DriverSupportFeatures 339

28.4.2AutomatedDrivingFeatures 341

28.5DriverMonitoringSystems 342

28.6Conclusion 343 References 343

29WearableComputingSystems:State-of-the-ArtandResearch Challenges 349

GiancarloFortinoandRaffaeleGravina

29.1Introduction 349

29.2WearableDevices 350

29.2.1AHistoryofWearables 350

29.2.2SensorTypes 351

29.2.2.1PhysiologicalSensors 352

29.2.2.2InertialSensors 352

29.2.2.3VisualSensors 352

29.2.2.4AudioSensors 355

29.2.2.5OtherSensors 355

29.3BodySensorNetworks-basedWearableComputingSystems 355

29.3.1BodySensorNetworks 355

29.3.2TheSPINEBody-of-Knowledge 357

29.3.2.1TheSPINEFramework 357

29.3.2.2TheBodyCloudFramework 359

29.4ApplicationsofWearableDevicesandBSNs 360

29.4.1Healthcare 360

29.4.1.1CardiovascularDisease 362

29.4.1.2Parkinson’sDisease 362

29.4.1.3RespiratoryDisease 362

29.4.1.4Diabetes 363

29.4.1.5Rehabilitation 363

29.4.2Fitness 363

29.4.2.1DietMonitoring 363

29.4.2.2Activity/FitnessTracker 363

29.4.3Sports 364

29.4.4Entertainment 364

29.5ChallengesandProspects 364

29.5.1MaterialsandWearability 364

29.5.2PowerSupply 365

29.5.3SecurityandPrivacy 365

29.5.4Communication 365

29.5.5EmbeddedComputing,DevelopmentMethodologies,andEdgeAI 365

29.6Conclusions 365 Acknowledgment 366 References 366

30MultisensorWearableDeviceforMonitoringVitalSignsandPhysical Activity 373

JoshuaDiTocco,LuigiRaiano,DanielaloPresti,CarloMassaroni,DomenicoFormica,and EmilianoSchena

30.1Introduction 373

30.2Background 373

30.2.1Context 373

30.2.2BasicDefinitions 374

30.3RelatedWork 375

30.4CaseStudy:MultisensorWearableDeviceforMonitoringRRandPhysical Activity 376

30.4.1WearableDeviceDescription 376

30.4.1.1ModulefortheEstimationofRR 377

30.4.1.2ModulefortheEstimationofPhysicalActivity 377

30.4.2ExperimentalSetupandProtocol 378

30.4.2.1ExperimentalSetup 378

30.4.2.2ExperimentalProtocol 378

30.4.3DataAnalysis 378

30.4.4Results 378

30.5Conclusions 379

30.6FutureResearchChallenges 380 References 380

31IntegrationofMachineLearningwithWearableTechnologies 383 DariusNahavandi,RoohallahAlizadehsani,andAbbasKhosravi

31.1Introduction 383

31.2Background 384

31.2.1HistoryofWearables 384

31.2.2SupervisedLearning 384

31.2.3UnsupervisedLearning 386

31.2.4DeepLearning 386

31.2.5DeepDeterministicPolicyGradient 387

31.2.6CloudComputing 388

31.2.7EdgeComputing 388

31.3StateoftheArt 389

31.4FutureResearchChallenges 392 References 393

32Gesture-BasedComputing 397 GennaroCostagliola,MattiaDeRosa,andVittorioFuccella

32.1Introduction 397

32.2Background 398

32.2.1HistoryoftheDevelopmentofGesture-BasedComputing 398

32.2.2BasicDefinitions 399

32.3StateoftheArt 399

32.4FutureResearchChallenges 402

32.4.1CurrentResearchIssues 402

32.4.2FutureResearchDirectionsDealingwiththeCurrentIssues 403 Acknowledgment 403 References 403

33EEG-basedAffectiveComputing 409 XueliangQuanandDongruiWu

33.1Introduction 409

33.2Background 409

33.2.1BriefHistory 409

33.2.2EmotionTheory 410

33.2.3EmotionRepresentation 410

33.2.4EEG 410

33.2.5EEG-BasedEmotionRecognition 411

33.3State-of-the-Art 411

33.3.1PublicDatasets 411

33.3.2EEGFeatureExtraction 411

33.3.3FeatureFusion 412

33.3.4AffectiveComputingAlgorithms 413

33.3.4.1TransferLearning 413

33.3.4.2ActiveLearning 413

33.3.4.3DeepLearning 413

33.4ChallengesandFutureDirections 414 Acknowledgment 415 References 415

34SecurityofHumanMachineSystems 419 FrancescoFlammini,EmanueleBellini,MariaStelladeBiase,andStefanoMarrone

34.1Introduction 419

34.2Background 420

34.2.1AnHistoricalRetrospective 420

34.2.2FoundationsofSecurityTheory 421

34.2.3AReferenceModel 421

34.3StateoftheArt 422

34.3.1SurveyMethodology 422

34.3.2ResearchTrends 425

34.4ConclusionsandFutureResearch 426 References 428

35IntegratingInnovation:TheRoleofStandardsinPromotingResponsible DevelopmentofHuman–MachineSystems 431 ZachMcKinney,MartijndeNeeling,LuigiBianchi,andRicardoChavarriaga

35.1IntroductiontoStandardsinHuman–MachineSystems 431

35.1.1WhatAreStandards? 431

35.1.2StandardsinContext:TechnologyGovernance,BestPractice,andSoftLaw 432

35.1.3TheNeedforStandardsinHMS 433

35.1.4BenefitsofStandards 433

35.1.5WhatMakesanEffectiveStandard? 434

35.2TheHMSStandardsLandscape 435

35.2.1StandardsinNeuroscienceandNeurotechnologyforBrain–MachineInterfaces 435

35.2.2IEEEP2731–UnifiedTerminologyforBCI 435

35.2.2.1TheBCIGlossary 439

35.2.2.2TheBCIFunctionalModel 439

35.2.2.3BCIDataStorage 439

35.2.3IEEEP2794–ReportingStandardfor invivo NeuralInterfaceResearch(RSNIR) 441

35.3StandardsDevelopmentProcess 443

35.3.1WhoCanParticipateinStandardsDevelopment? 443

35.3.2WhyShouldIParticipateinStandardsDevelopment? 444

35.3.3HowCanIgetInvolvedinStandardsDevelopment? 444

35.4StrategicConsiderationsandDiscussion 444

35.4.1ChallengestoDevelopmentandBarrierstoAdoptionofStandards 444

35.4.2StrategiestoPromoteStandardsDevelopmentandAdoption 445

35.4.3FinalPerspective:OnInnovation 445 Acknowledgments 446 References 446

36SituationAwarenessinHuman-MachineSystems 451 GiuseppeD’AnielloandMatteoGaeta

36.1Introduction 451

36.2Background 452

36.3State-of-the-Art 453

36.3.1SituationIdentificationTechniquesinHMS 454

36.3.2SituationEvolutioninHMS 455

36.3.3Situation-AwareHumanMachine-Systems 455

36.4DiscussionandResearchChallenges 456

36.5Conclusion 458 References 458

37Modeling,Analyzing,andFosteringtheAdoptionofNewTechnologies:The CaseofElectricVehicles 463

ValentinaBreschi,ChiaraRavazzi,SilviaStrada,FabrizioDabbene,andMaraTanelli

37.1Introduction 463

37.2Background 464

37.2.1AnAgent-basedModelforEVTransition 464

37.2.2CalibrationBasedonRealMobilityPatterns 466

37.3FosteringtheEVTransitionviaControloverNetworks 468

37.3.1RelatedWork:APerspectiveAnalysis 468

37.3.2ANewModelforEVTransitionwithIncentivePolicies 469

37.3.2.1ModelingTime-varyingThresholds 469

37.3.2.2CalibrationoftheModel 470

37.4BoostingEVAdoptionwithFeedback 470

37.4.1FormulationoftheOptimalControlProblem 470

37.4.2DerivationoftheOptimalPolicies 471

37.4.3ARecedingHorizonStrategytoBoostEVAdoption 472

37.5ExperimentalResults 473

37.6Conclusions 476

37.7FutureResearchChallenges 477 Acknowledgments 477 References 477

Index 479

EditorsBiography

GiancarloFortino(IEEEFellow’22)isfullprofessorofComputerEngineeringintheDepartment ofInformatics,Modeling,Electronics,andSystemsattheUniversityofCalabria(Unical),Italy. HehasaPhDinSystemsandComputerEngineeringfromUniversityofCalabriain2000.His researchinterestsincludewearablecomputingsystems,InternetofThings,andcybersecurity.He isnamedHighlyCitedResearcher2002–2022byClarivateinComputerScience.Hehasauthored morethan650papersininternationaljournals,conferences,andbooks.Heis(founding)series editoroftheIEEEPressBookSeriesonHuman–MachineSystemsandoftheSpringerInternet ofThingsseries,andisAssociateEditorofpremierIEEETransactions.HeiscofounderandCEO ofSenSysCalS.r.l.,aUnicalspinofffocusedoninnovativeIoTsystems,andcofounderofBigTech S.r.l.,astartupfocusedonAI-drivensystemsandBigData.Fortinoiscurrentlyamemberofthe IEEESMCSBoGandco-chairoftheSMCSTConIWCD.

DavidKaberiscurrentlytheDean’sLeadershipProfessorandChairoftheDepartmentofIndustrialandSystemsEngineeringattheUniversityofFlorida(UF).PriortojoiningUF,Kaberwasa distinguishedprofessorofindustrialengineeringatNorthCarolinaStateUniversitywherehealso servedastheDirectorofResearchfortheErgonomicsCenterofNorthCarolina.Kaber’sprimary areaofresearchinterestishuman-systemsengineeringwithafocusonhuman–automaton interaction,includingdesignandanalysisforsituationawarenessincomplexhumanin-the-loop systems.Domainsofstudyforhisresearchhaveincludedphysicalworksystems,industrialsafety systems,roboticsystems,transportationsystems,andhealthcare.KaberisafellowofIEEEand previouseditor-in-chiefofthe IEEETransactionsonHuman–MachineSystems.Heisafellowof InstituteofIndustrialEngineersandafellowoftheHumanFactorsandErgonomicsSociety.Kaber isalsoaCertifiedHumanFactorsProfessional(BCPE)andaCertifiedSafetyProfessional(BCSP).

AndreasNürnbergerisprofessorofDataandKnowledgeEngineeringattheOtto-von-Guericke UniversitätMagdeburg(OVGU),Germany.Hisresearchfocusesonadaptivityinhuman–machine systems,consideringaspectssuchasuserbehavioranalysisandintelligentuserassistance.He wasinvolvedintheorganizationofmanyconferencesandworkshopsinrelatedareasandthe developmentofnewscientificevents,amongothers,theIEEESMCSsponsoredinternational conferenceseriesonHuman–MachineSystems(IEEEICHMS).Andreaswasvisitingresearcher attheUniversityofMelbourne,Australia;postdocatUCBerkeley,UnitedStates;andvisiting professoratUniversitéPierreetMarieCurie,Paris.AndreasisanEmmyNoetherFellowofthe GermanScienceFoundation(DFG).

DavidMendonça(SeniorMember,2012)isSeniorPrincipalDecisionScientistatMITRECorporation.HepreviouslyheldtherankofprofessorintheDepartmentofIndustrialandSystems EngineeringandintheDepartmentofCognitiveScienceatRensselaerPolytechnicInstitute. HeservedasaProgramDirectorattheNationalScienceFoundationfrom2015to2017.Hewas avisitingscholarattheUniversityofLisbon(Portugal)andatDelftUniversityofTechnology (TheNetherlands).HeiscurrentlyamemberoftheBoardofGovernorsoftheIEEESystems, ManandCyberneticsSociety,andoftheIEEEBoston(Massachusetts)Section.HeholdsaPhD inDecisionSciencesandEngineeringSystemsfromRensselaerPolytechnicInstitute,anMSfrom CarnegieMellonUniversity,andaBAfromUniversityofMassachusetts/Amherst.

ListofContributors

Marie-HélèneAbel HeudiasycLaboratory UniversityofTechnologyofCompiègne Compiègne

France

RoohallahAlizadehsani InstituteforIntelligentSystemsResearchand Innovation(IISRI) DeakinUniversity WaurnPonds,VIC

Australia

TerryAmorese DepartmentofPsychology UniversitàdellaCampania“L.Vanvitelli” Caserta

Italy

AbdelkaderNasreddineBelkacem DepartmentofComputerandNetwork Engineering CollegeofInformationTechnology UnitedArabEmiratesUniversity AlAin

UAE

EmanueleBellini DipartimentodiMatematicaeFisica UniversitádegliStudidellaCampania “LuigiVanvitelli” Caserta

Italy

KawtarBenghazi UniversidaddeGranada Granada

Spain

LuigiBianchi DepartmentofCivilEngineeringand ComputerScienceEngineering “TorVergata”UniversityofRome

Rome

Italy

MariaStellaDeBiase DipartimentodiMatematicaeFisica UniversitádegliStudidellaCampania “LuigiVanvitelli”

Caserta

Italy

ThomasBohné DepartmentofEngineering InstituteforManufacturing UniversityofCambridge

Cambridge

UK

StefanieS.Bradley IIIBloorviewResearchInstitute HollandBloorviewKidsRehabilitation Hospital

Toronto Canada

ListofContributors

ValentinaBreschi

DepartmentofElectricalEngineering EindhovenUniversityofTechnology Eindhoven Netherlands

ZoraidaCallejas UniversidaddeGranada Granada

Spain

MaximilianoCanche FacultyofMathematics UniversidadAutónomadeYucatán Mérida,Yucatán Mexico

FilippoCantucci

TrustTheoryandTechnologyGroup InstituteofCognitiveSciencesand Technologies NationalResearchCouncilofItaly

Rome Italy

TomCarlson AspireCreate UniversityCollegeLondon Stanmore,Middlesex UK

CristianoCastelfranchi

TrustTheoryandTechnologyGroup InstituteofCognitiveSciencesand Technologies NationalResearchCouncilofItaly

Rome Italy

TomChau IIIBloorviewResearchInstitute HollandBloorviewKidsRehabilitation Hospital

Toronto Canada

RicardoChavarriaga CentreforArtificialIntelligence SchoolofEngineering ZurichUniversityofAppliedSciencesZHAW Winterthur Switzerland and CLAIREOfficeSwitzerland,ZHAWdigital ZurichUniversityofAppliedSciences Winterthur Zürich Switzerland

JessieY.C.Chen U.S.ArmyResearchLaboratory AberdeenProvingGround,Maryland USA

MinChen SchoolofComputerScienceandTechnology HuazhongUniversityofScienceand Technology

Wuhan China

WeiChen StateKeyLabofCAD&CG ZhejiangUniversity Hangzhou

China

GennaroCordasco DepartmentofPsychology UniversitàdellaCampania“L.Vanvitelli” Caserta

Italy

AlessandroCorrea-Victorino HeudiasycLaboratory UniversityofTechnologyofCompiègne Compiègne

France

GennaroCostagliola DipartimentodiInformatica UniversitàdiSalerno ViaGiovanniPaoloII,132,84084 Fisciano(SA)

Italy

MarialuciaCuciniello DepartmentofPsychology UniversitàdellaCampania“L.Vanvitelli” Caserta

Italy

GiuseppeD’Aniello DepartmentofInformationandElectrical EngineeringandAppliedMathematics UniversityofSalerno Fisciano(SA)

Italy

FabrizioDabbene IstitutodiElettronicaeIngegneria dell’Informazioneedelle Telecomunicazioni–IEIIT CentroNazionaledelleRicerche Torino

Italy

ArwenH.DeCostanza U.S.DEVCOM ArmyResearchLaboratory AberdeenProvingGround,MD USA

YulinDeng CepheidHumanFactorsandEngineering Team Sunnyvale,CA USA

BirsenDonmez DepartmentofMechanicalandIndustrial Engineering UniversityofToronto Toronto,ON Canada

AnnaEsposito DepartmentofPsychology

UniversitàdellaCampania“L.Vanvitelli” Caserta

Italy

RinoFalcone TrustTheoryandTechnologyGroup InstituteofCognitiveSciencesand Technologies

NationalResearchCouncilofItaly

Rome

Italy

TiagoH.Falk Institutnationaldelarecherchescientifique UniversityofQuebec Montreal,Quebec Canada ScottFang TorontoResearchCenter DefenceResearchandDevelopmentCanada Toronto Canada

PhilipS.E.Farrell TorontoResearchCenter DefenceResearchandDevelopmentCanada Toronto Canada

FedericoFaruffini HeudiasycLaboratory UniversityofTechnologyofCompiègne Compiègne France and DIBRIS UniversityofGenoa

Genoa

Italy

xxvi ListofContributors

FrancescoFlammini SchoolofInnovation,Design,andEngineering MälardalenUniversity Eskilstuna Sweden

EricaD.Floreani IBCI4Kids UniversityofCalgary Calgary Canada and IIDepartmentofPediatrics AlbertaChildren’sHospital Calgary Canada

DomenicoFormica SchoolofEngineering NewcastleUniversity UK

GiancarloFortino DepartmentofInformatics,Modeling ElectronicsandSystems UniversityofCalabria Rende Italy

VittorioFuccella DipartimentodiInformatica UniversitàdiSalerno Fisciano(SA) Italy

MatteoGaeta DepartmentofInformationandElectrical EngineeringandAppliedMathematics UniversityofSalerno Fisciano(SA)

Italy

MiladGeravand DeepCareGmbH Waiblingen Germany

RaffaeleGravina DepartmentofInformatics,Modeling ElectronicsandSystems UniversityofCalabria Rende

Italy

DavidGriol UniversidaddeGranada Granada

Spain

StephanieGross AustrianResearchInstituteforArtificial Intelligence

Vienna Austria

ChristophGuger g.tecmedicalengineeringGmbH g.tec Austria

BinGuo Departmentofintelligentcomputingsystem SchoolofComputerScience NorthwesternPolytechnicalUniversity Xi’an China

LydiaHabib DepartmentofAutomationandControl Univ.PolytechniqueHauts-de-France,CNRS UMR8201–LAMIH Valenciennes France

NiloufaralsadatHashemi IIIBloorviewResearchInstitute HollandBloorviewKidsRehabilitation Hospital Toronto Canada

KlausHauer

AgaplesionBethanien-Hospital,Geriatric Centre

UniversityofHeidelberg Heidelberg Germany

DengboHe

IntelligentTransportationThrust,SystemsHub HongKongUniversityofScienceand Technology(Guangzhou) Guangzhou China and DepartmentofCivilandEnvironmental Engineering

HongKongUniversityofScienceand Technology

HongKongSAR China

InaHeine OrganizationalDevelopment LaboratoryforMachineToolsandProduction Engineering

RWTHAachenUniversity Aachen,NRW Germany

ThomasHellebrandt OrganizationalDevelopment LaboratoryforMachineToolsandProduction Engineering

RWTHAachenUniversity Aachen,NRW Germany

ChristineHorner IIIBloorviewResearchInstitute HollandBloorviewKidsRehabilitation Hospital Toronto Canada

MingHou TorontoResearchCenter DefenceResearchandDevelopmentCanada Toronto Canada

LouisHuebser OrganizationalDevelopment LaboratoryforMachineToolsandProduction Engineering

RWTHAachenUniversity Aachen,NRW Germany

IztokHumar FacultyofElectricalEngineering UniversityofLjubljana Ljubljana

Slovenia

BrianIrvine IIDepartmentofPediatrics AlbertaChildren’sHospital Calgary Canada and IIIBloorviewResearchInstitute HollandBloorviewKidsRehabilitation Hospital Toronto Canada ZeannaJadavji IBCI4Kids UniversityofCalgary Calgary Canada

RadmilaJuric IndependentResearcherLondon UK

DavidB.Kaber

UniversityofFlorida DepartmentofIndustrialandSystems Engineering

Gainesville,FL

USA

DionKelly IBCI4Kids UniversityofCalgary

Calgary Canada and IIDepartmentofPediatrics

AlbertaChildren’sHospital Calgary Canada

AbbasKhosravi InstituteforIntelligentSystemsResearchand Innovation(IISRI) DeakinUniversity WaurnPonds,VIC Australia

EliKinney-Lang IBCI4Kids UniversityofCalgary Calgary Canada and IIDepartmentofPediatrics

AlbertaChildren’sHospital

Calgary Canada

AdamKirton IBCI4Kids UniversityofCalgary

Calgary Canada and IIDepartmentofPediatrics AlbertaChildren’sHospital

Calgary Canada

BrigitteKrenn AustrianResearchInstituteforArtificial Intelligence Vienna Austria

AbderrahmaneLakas DepartmentofComputerandNetwork Engineering CollegeofInformationTechnology UnitedArabEmiratesUniversity AlAin UAE

QingyangLi Departmentofintelligentcomputingsystem SchoolofComputerScience NorthwesternPolytechnicalUniversity Xi’an China

BangliLiu SchoolofComputerScienceandInformatics FacultyofComputing,Engineering,andMedia DeMontfortUniversity Leicester,England

UK

HonghaiLiu SchoolofComputing,FacultyofTechnology UniversityofPortsmouth Portsmouth,England

UK

JiaLiu

SchoolofComputerScienceandTechnology HuazhongUniversityofScienceand Technology

Wuhan China

ElliotLoh DefenceResearchandDevelopmentCanada NationalDefence/GovernmentofCanada Ottawa,ON Canada

MonikaLohani UniversityofUtah DepartmentofPsychology SaltLakeCity,UT USA

StefanoMarrone DepartmentofPsychology UniversitàdellaCampania“L.Vanvitelli”

Caserta Italy and DipartimentodiMatematicaeFisica UniversitádegliStudidellaCampania “LuigiVanvitelli” Caserta

Italy

CarloMassaroni DepartmentalFacultyofEngineering UniversitàCampusBio-MedicodiRoma Rome Italy

ZachMcKinney IEEEStandardsAssociation Piscataway,NJ USA

DavidMendonça MITRECorporation Bedford,MA USA

MircoMoencks DepartmentofEngineering InstituteforManufacturing UniversityofCambridge Cambridge UK

DariusNahavandi InstituteforIntelligentSystemsResearchand Innovation(IISRI) DeakinUniversity WaurnPonds,VIC Australia

MartijndeNeeling DepartmentofNeurology AmsterdamUniversityMedicalCenters(UMC) Amsterdam

Netherlands

AndreasNürnberger FacultyofComputerScience Otto-von-Guericke-UniversitätMagdeburg Magdeburg Germany

SergioF.Ochoa ComputerScienceDepartment UniversityofChile Santiago,RM Chile

Marie-PierrePacaux-Lemoine DepartmentofAutomationandControl Univ.PolytechniqueHauts-de-France,CNRS UMR8201–LAMIH Valenciennes France

MarcosPadrón OrganizationalDevelopment LaboratoryforMachineToolsandProduction Engineering RWTHAachenUniversity Aachen,NRW Germany

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symptoms of, 60 temporosphenoidal, 569 of tonsils, 662 treatment of, 60

Abstraction of blood, 182

A. C. E. mixture, 198

Accommodation, defects of, 604

Acetabulum, migration of, 453

Acetonemia, 82

Acetonuria, 82

Acheilia, 638

Achondroplasia, 432

Acid intoxication from anesthetics, 203

Acinous carcinoma, 290

Acoustic nerve, neurofibroma of, 584

Acromegaly, 437

Acromial process, fracture of, 494

Actinomycis, 109 fungi, 55

Actinomycosis, 109 of abdominal wall, 783 of bone, 432 of breast, 759 definition of, 109 diagnosis of, 110 of face, 640 of intestines, 827 of kidneys, 964 of liver, 914 of lung, 732, 734 of mesentery, 939 of mouth, 657 organism of, 109 prognosis of, 110 pus in, 109 of skin, 308 of thorax, 729

of tongue, 659 treatment of, 110

Adenocarcinoma, 285 of bladder, 992 of pancreas, 953

Adenoids of pharynx, 679 treatment of, 680

Adenoma, 284 of bladder, 992 of breast, 760 of kidney, 969 congenital, 969 of liver, 914 of pancreas, 953 of rectum, 885 sebaceous, 285 cysts, 285 of thyroid, 712

Adenosarcoma, embryonal, 268

Adventitious bursæ, 263

Ainhum, 76

Air embolism, 38 of veins, 363 Aleppo boil, 309

Alimentary canal, infection through, 49

Allantoic cysts, 260

Alveolar sarcoma, 274 suppuration, 664

Alypin, 207

Amastia, 755

Amazia, 755

Amputations, 1023 of arm, 1032 atypical, 1023 control of hemorrhage in, 1024 of elbow, 1031 of finger, 1029

of foot, 1037, 1041

Bruns’ method, 1042

partial, 1034

Teale’s method, 1042 of forearm, 1031 of hand, 1031 of hip-joint, 1045

Davey’s method, 1045

McBurney’s method, 1045

Woodbury’s method, 1045

Wyeth’s method, 1045 interscapularthoracic, 1033 of knee, 1043

Gritti’s method, 1044

Sabanejeff’s method, 1044

Stephen Smith’s method, 1043 of leg, 1039

Bier’s osteoplastic, 1028

circular, 1041

Pirogoff’s method, 1040 of lower extremity, 1034

mediotarsal of Chopart, 1037 method of, 1026 circular, 1026

flap, 1027

osteoplastic, 1027 of penis, 1010 of shoulder, 1032 stump after, 1046 bad, 1046 good, 1046

neuromas, 1047

supracondyloid, 1043 of thigh, 1043

above knee, 1044

Gritti’s method, 1043

Stokes’ method, 1043

of thumb, 1029 tibiotarsal, 1037 of toes, 1034 typical, 1023 of upper extremity, 1029 cineplastic, 1048 entire, 1033 of wrist, 1031

Anastomosis of arteries, aneurysm by, 344 gastric, 816 of intestines, 842

Anastomotic varix, 364

Anel’s method of treating aneurysm, 347

Anemia, 30 pernicious, 30 primary, 30 secondary, 30 splenic, 31

Anesthesia and anesthetics, 192

A. C. E. mixture, 198 accidents from, 201 arrested respiration, 202 treatment of, 202 cardiac failure, 201 acid intoxication from, 203 administration of, 193 anesthol, 200 chloroform, 195 accidents from, 196 action of, 196 administration of, 197 death from, 196 choice of, 200 dangers of, 201 discovery of, 192 ether, 193 accidents due to, 194

action of, 194

narcosis by rectum, 195 petroleum, 199

sequels from administration of, 195 ethyl bromide, 198

chloride, 199

local use of, 199

intraspinal, 207 local, 205

alypin, 207

anesthesin, 207

beta-eucaine, 207

cocaine, 205 liquid air, 205 nervanin, 207 orthoform, 207 stovaine, 207

magnesium salts, 209 management of, 192 methylene bichloride, 198 morphine, 205

nitrous oxide gas, 200 scopolamine, 205 somnoform, 199

Anesthesin, 207

Aneurysmal bruit, 341 varix, 363 of abdominal aorta, 346 arteriovenous, 344 of axillary artery, 345 of carotid artery, 345 external, 345 internal, 345 cirsoid, 278, 339, 344 classification of, 342 diagnosis of, 345 diffuse, 339, 342

dissecting, 339, 342 false, 339, 343 of femoral artery, 346 fusiform, 339, 343 of heart, 732 hernial, 339 of iliac artery, 346 of innominate artery, 345 intracranial, 345 of liver, 914 of neck, 701 of orbit, 592 progress of, 341 pulsation of, 341 racemose, 344 rupture of, 341 sacculated, 339, 342 spontaneous, 339 of subclavian artery, 345 traumatic, 339, 343 treatment of, 346 by extirpation, 348 by introduction of wire, 348 by ligation, 347

Anel’s method, 347

Brasdor’s method, 347 Hunter’s method, 347 Wardrop’s method, 347 by open division, 347 by opening and suture, 348 true, 339 varicose, 339, 342, 363

Angina, Ludwig’s, 658, 703 Vincent’s, 703

Angiocholitis, desquamating, 919

Angioma, 277 arterial, 278

capillary, 277 cavernous, 277 of omentum, 935 of orbit, 592 plexiform, 278 of veins, 366 treatment of, 367

Angiosarcoma, 275

Angiotribe, control of hemorrhage by, 236

Ankle, dislocations of, 544 excision of, 414

Ankyloblepharon, 603

Ankyloglossum, 652

Ankylosis, 403 contractures, 403 of hip, 404 of jaw, 667 of knee, 404 treatment of, 405 true, 403

Annular thrombosis, 35

Anthrax, 106 bacillus of, 54 definition of, 106 incubation in, 107 postmortem appearances in, 107 prognosis of, 107 prophylaxis of, 108 symptoms of, 107 treatment of, 107

Antisepsis, 243

Antiseptic applications, 248 solutions, 248

Antiseptics, toxic, 175

Antitoxin treatment of tetanus, 101

Antrum of Highmore, operations on, 611

Anus, absence of, 873

artificial, 839 congenital defects of, 872 fissures of, 876 imperforate, 873 malformations of, 872

Aorta, abdominal, aneurysm of, 346 ligation of, 356

Aplasia cranii, 547

Aponeurotomy, 327

Apoplectic cysts, 952

Apoplexia neonatorum, 564

Apoplexies, compression, 560

Appendicitis, bacteriology of, 852 causes of, 854 chronic, operation for, 866 complications of, 855 diagnosis of, 857 from acute obstruction of bowel, 858 pancreatitis, 858 from cholecystitis, 857 from colitis, 857 from enterocolitis, 857 from floating kidney, 858 from gastric ulcers, 857 from intestinal ulcers, 857 from lead colic, 858 from mesenteric embolism, 858 thrombosis, 858 from peritonitis, 857 from psoas abscess, 859 from pyosalpinx, 858 from ruptured extra-uterine pregnancy, 858 from strangulated hernias, 858 McBurney’s point in, 855 recurrent, 854 operation for, 866 symptoms of, 859

acute, 855

abdominal distention, 856

bowels, 856

jaundice, 856

muscle spasm, 855

pain, 855

pulse, 856

temperature, 856

tenderness, 855

tumor, 856

vomiting, 856 treatment of, 861

non-operative, 862 operative, 862

indications for, 862 in typhoid fever, 859

Appendicostomy, 850

Appendicular colic, 853

Appendix, vermiform. See Vermiform appendix.

Aprosopia, 638

Arlt’s operation for blepharoplasty, 602

Arm, amputation of, 1032

Arrow poisoning, 173

Arterial angioma, 278

Arteries, abdominal aorta, aneurysm of, 346 ligation of, 356 aneurysm of, 339 by anastomosis, 344 arteriovenous, 344 cirsoid, 339, 344 classification of, 342 diagnosis of, 345 diffuse, 339, 342 dissecting, 339, 342 false, 339, 342 fusiform, 339, 343 hernial, 339

progress of, 341 pulsation of, 341 racemose, 344 rupture of, 341 sacculated, 339, 342 spontaneous, 339 traumatic, 339, 343 treatment of, 346 true, 339 varicose, 339, 344 axillary, aneurysm of, 345 ligation of, 355 brachial, ligation of, 355 calcification of, 339 carotid, aneurysm of, 345 common, ligation of, 351 external, aneurysm of, 345 excision of, 352 ligation of, 352 injuries, 563 internal, aneurysm of, 345 ligation of, 352 circumflex, ligation of, 359 epigastric, ligation of, 359 facial, ligation of, 352 fatty degeneration of, 339 femoral, aneurysm of, 346 ligation of, 359 iliac, aneurysm of, 346 common, ligation of, 356 external, ligation of, 357 internal, ligation of, 357 innominate, aneurysm of, 345 ligation of, 350 ligation of, 350 gangrene from, 73 lingual, ligation of, 352

middle meningeal, injuries of, 563

occipital, ligation of, 352

popliteal, ligation of, 360 radial, ligation of, 356

subclavian, aneurysm of, 345 ligation of, 354 surgical diseases of, 337 temporal, ligation of, 35

thyroid, inferior, ligation of, 353 tibial, anterior, ligation of, 360 posterior, ligation of, 360 ulnar, ligation of, 356 vertebral, ligation of, 353

Arteriorrhaphy in treatment of aneurysm, 348

Arteriosclerosis, 339

Arteriotomy, 183

Arteriovenous aneurysm, 344, 564

Arteritis, 338

Arthrectomy, 400

Arthritis, 382 chronic, 386 treatment of, 386 deformans, 387 treatment of, 389 gonorrheal, 392 postgonorrheal, 152, 392 of jaw, 667 rheumatoid, 387 syphilitic, 385 tuberculous, 393 diagnosis of, 398 pathology of, 394 symptoms of, 397 treatment of, 398

Arthropathic joint disease, 394

Arthrotomy, 400

Artificial respiration, 204

Howard’s method, 204

Marshall Hall’s method, 204 in shock, 180

Sylvester’s method, 204

Ascites, chylous, 368

Ascitic tuberculous peritonitis, 791

Asepsis, 243 sterilization, 243 by boiling water, 244 of dressings, 247 by formalin, 244 fractional, 244 of hands, 245 by heat, 243 of instruments, 246 by mustard flour, 245 of sponges, 247 of suture materials, 247

Aseptic wound fever, 85. See Surgical fever.

Aspergillus fungi, 56

Aspiration, paracentesis by, 184

Asthma, thymic, 163

Astomia, 638

Astragalectomy, 467

Astragalus, dislocation of, 544

Atheroma of arteries, 339

Atheromatous abscess, 73, 339 cysts of neck, 707 of skin, 310 ulcer, 339

Atresia of rectum, 872

Atrophic elongation of bones, 436

Atrophy of bone, 422 of brain, 578 definition of, 26 of muscles, 332 treatment of, 332

pathological, 26 physiological, 26 senile, 26 of skull, 547 of testicle, 1015 trophoneurotic, 27 of veins, 361

Auricle, rodent ulcer of, 606

Auricles, supernumerary, 605, 638

Auto-intoxication, 79 cause of, 79 ferments in, 79 intestinal putrefaction in, 81 osmotic pressure of blood in, 80 potassium salts in, 80 treatment of, general, 83 venesection in, 80 urea in, 80, 81

Axilla, syphilis of, 751 tuberculosis of, 751

Axillary artery, aneurysm of, 345 ligation of, 355

B

B aërogenes capsulatus, 55 anthracis, 54 bubonic plague, 54 chancroid, 55 coli communis, 53 diphtheriæ, 54 lepræ, 54 mallei, 54

œdematis maligni, 54 pneumoniæ, 54 proteus, 53

pyocyaneus, 53 of Rauschbrand, 55 of rhinoscleroma, 54, tetani, 54 of tuberculosis, 54

typhi abdominalis, 53

Bacteria of pus formation, 51 facultative pyogenic, 53

bacillus aërogenes capsulatus, 55 anthracis, 54

bubonic plague, 54 chancroid, 55

diphtheriæ, 54 lepræ, 54 mallei, 54

œdematis maligni, 54 proteus, 53 pneumoniæ, 54 of Rauschbrand, 55 of rhinoscleroma, 54 tetani, 54 tuberculosis, 54 typhi abdominalis, 53 obligate pyogenic, 52

bacillus, pyocyaneus, 53 coli communis, 53 colon bacillus, 53

diplococcus pneumoniæ, 53 micrococcus gonorrhœæ, 53 lanceolatus, 53 tetragenus, 53

staphylococcus pyogenes albus, 52 aureus, 52 epidermidis, 52

streptococcus erysipelatus, 52 pyogenes, 52

Bacterial determination of pus as an indication to treatment, 57

Balanitis, 149, 1005

Balanoposthitis, 149, 1005

Bandage, elastic, for control of hemorrhage, 234

Bandaging, 189 kinds of, 189, 190, 191 materials used in, 191

Banti’s disease, 31, 942

Barbadoes leg, 372

Barrel-shaped chest, 719

Barton’s head bandage, 191

Basedow’s disease, 713

Bassini’s operation for hernia, 902

Bastard clap, 148

Bed-sores, a cause of gangrene, 74

Bees, poisoning by, 172

Bell’s palsy, 640

Bellocq’s cannula, 681

Bennett’s fracture, 506

Beta-cocaine, 207

Beta-eucaine, 207

Bichat, fatty ball of, 641

Bier’s osteoplastic amputation of leg, 1028 permanent hyperemia in tuberculosis, 120 treatment of tuberculosis of joints, 399

Biett’s collarette, 131

Bifid penis, 1004 tongue, 652

Biliary calculi, 922 diagnosis of, 925 symptoms of, 924 treatment of, 926 colic, 922 symptoms of, 924 ducts, stricture of, 921

fistulas, 917

intestinal, 917 pathological, 917

postoperative, 917 passages, catarrh of, acute, 918 treatment of, 918 chronic, 918 injuries of, 918 operations on, 927 perforation of, 921 ulceration of, 921 symptoms of, 922 treatment of, 922

Billroth’s chain-stitch suture, 241

Biskra button, 309

Bladder, adenocarcinoma of, 992 adenoma of, 992 calculi of, 986 symptoms of, 986 treatment of, 987 congenital malformations of, 977 dermoid cysts of, 992 ectopia of, 978 treatment of, 978 examination of, 977 exstrophy of, 978 treatment of, 978 fibroma of, 992 foreign bodies in, 982 inflammation of, 984 symptoms of, 984 treatment of, 985 injuries to, 981 treatment of, 981 myxoma of, 992 papilloma of, 992 siphonage of, 1003 tuberculosis of, 118 tumors of, 992 symptoms of, 992

treatment of, 992 wounds of, 233

Blastomycetic dermatitis, 309 lesions of mouth, 658 pus, 56

Blennorrhea, 146. See Gonorrhea.

Blepharitis, 601 marginalis, 601

Blepharoplasty, 602

Arlt’s method for, 602

Dieffenbach’s method for, 603

Fricke’s method for, 603

Richet’s method for, 603

Blood, abstraction of, 182 by arteriotomy, 183 by cupping, 183 by leeching, 183 by venesection, 182

extravasation of, gangrene from, 73 foreign bodies in, 35 formed elements of, 29

glycogen in, 33 infusion of, 185 intravenous, 186 iodine reaction of, 33

osmotic pressure of, in auto-intoxication, 80 microörganisms in, 35 platelets, 30

surgical pathology of, 28 transfusion of, 185

Bloodvessels, injuries of, 216 suture of, 349 end-to-end, 350 lateral, 349 wounds of, 216

Boils, 304

oriental, 309

treatment of, 304

Bones, abscess of, 419, 425 treatment of, 426 achondroplasia, 432 acromegaly, 437 actinomycosis of, 432 atrophic elongation of, 436 atrophy of, 422 caries of, 427 cavalryman’s, 331 cavities, filling of, 431 cranial, acromegaly of, 548 injuries of, 552 leontiasis of, 548 osteomyelitis of, 548 periostitis of, 548 dancer’s, 331 diseases of, parasitic, 432 trophoneurotic, 432 epiphysitis of, acute, 421 exostoses of, 441 fencer’s, 331 fibroma of, 438 fragility of, 435 senile, 436 hydatid disease of, 432 treatment of, 432 hyperostoses of, 441 hypertrophy of, 422 injuries of, 218 leontiasis of, 438 myeloma of, 442 myxoma of, 441 necrosis of, 428 pathological, 428 toxic, 428 treatment of, 428

traumatic, 428 osteoarthropathic hypertrophiante pneumique, 436 osteoma of, 441 osteomalacia of, 434 prognosis of, 434 treatment of, 435 osteomyelitis of, acute, 416 complications of, 419 diagnosis of, 419 etiology of, 419 organisms at fault in, 417 pathology of, 416 prognosis of, 418 symptoms of, 418 treatment of, 419 chronic, 421 tuberculous, 423 latent, 421 osteoporosis of, 422 osteopsathyrosis, 435 osteosclerosis of, 422 ostitis deformans, 436 Paget’s disease of, 436 periostitis, acute infectious, 420 causes of, 421 treatment of, 421 albuminosa, 421 rachitis, 433 rider’s, 331 sarcoma of, 441 treatment of, 441 sequestrum formation of, 429 treatment of, 429 of skull, incomplete formation of, 547 syphilis of, 135, 426 transplantation of, 431 tuberculosis of, 116, 422

acute miliary, 423 pathology of, 423 symptoms of, 423 treatment of, 425 tumors of, 438 cartilaginous, 440

Boric acid, toxic effects of, 175

Bow-leg, 465 treatment of, 465

Brachial artery, ligation of, 355 plexus, operations on, 623

Brain, abscess of, 567 symptoms of, 568 prognosis of, 569 treatment of, 573 atrophy of, 578 compression of, 560 symptoms of, 561 prognosis of, 562 treatment of, 562 concussion of, 559 treatment of, 559 contusion of, 559 symptoms of, 560 treatment of, 560 cysts of, congenital, 578 foreign bodies in, 565 hernia of, 566 treatment of, 566 prolapsus of, 566 treatment of, 566 substance, injuries of, 564 lacerations of, 564 prognosis of, 564 symptoms of, 565 syphilis of, 138 tumors of, 582

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