H E A LT H
NEW HOPE FOR OSTEOARTHRITIS SUFFERERS Studies have shown that undenatured type II collagen (UC-II) is effective in the treatment of rheumatoid arthritis, and preliminary human and animal trials have shown it to be effective in treating osteoarthritis (OA).
T
soup prevented the mobilisation of immune system cells to sites of inflammation. Upon further
here are several types of
appears to reduce autoimmunity
analysis, they found it was not
collagen. The main ones,
to the body’s own CII, resulting in
vegetables, but a component of the
however, are designated
less inflammation in instances of
chicken broth itself that exerted
type I, type II and type III. While
osteoarthritis and rheumatism
this anti-inflammatory activity.
type II collagen (CII) is found
and benefits to joint health.
only in cartilage, collagen types ligaments, bones and joints. CII
UNDENATURED TYPE-II COLLAGEN
is sold in dietary supplements
Scientists have discovered that
as collagen-II (denatured or
undenatured type II collagen
hydrolysed collagen type II
(UC-II) retrains killer T-cells
protein) or as undenatured
(that destroy target cells) so they
collagen type II (also known as
recognise collagen as a harmless
native). Oral administration of CII
substance, preventing the joint
is used to reduce clinical signs
damage seen in osteoarthritis.
I and III are found together in
of osteoarthritis. CII is a peptide and component of joint cartilage. Its oral ingestion
UC-II was discovered when a
Undenatured type II collagen administered orally works with a healthy immune system to promote healthy joints by a process called oral tolerisation.
Chicken-derived CII was found to regulate the immune system and prevent the attack of proteins and healthy joint cartilage. UC-II has been proven to activate a pathway known as induced oral tolerance, which teaches the immune system to correctly recognise cartilage proteins as the body’s own tissues instead of as foreign microbes. Oral-induced tolerance thus prevents an inflammatory
team of scientists at the University
attack, a newly recognised cause
of Nebraska found that chicken
of osteoarthritis. Continued …
48
SILVER DIGEST // WINTER 2019
