The samples that Dr Amol Fatangare uses for his research are being stored at minus 80 degrees Celsius.
Blood Test for a Safe Diagnosis of Drug Allergies When a person’s immune system reacts to a drug in an undesired and extreme way, doctors refer to this as a drug allergy. Although allergies only make up a small amount of the side effects of drugs, the symptoms go beyond just itchy rashes and fever. In the most serious cases, drug allergies can cause severe and potentially fatal reactions such as difficulties in breathing, organ failure and circulatory arrest. According to the World Allergy Organization (WAO), drugs are among the most common triggers of anaphylactic shocks, the most severe form of an allergic reaction. That is why it is important for doctors to be able to diagnose drug allergies without any risks for patients. In the project »Analysis of Differential Gene and Protein Expression for In-vitro Detection of Drug Allergies« (INA), scientists at ISAS are working together with the Federal Institute for Drugs and Medical Devices, the Clinic for Dermatology and Allergology of RWTH Aachen University Hospital and the biomedicine company Life & Brain GmbH in Bonn, in order to make a simple blood test for the diagnosis of drug allergies possible.
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There are different ways to diagnose drug
Furthermore, they can directly expose pa-
allergies. For example, doctors can conduct
tients to a suspect drug via provocation tests.
skin tests like prick- or intradermal tests.
For the latter, patients take the relevant me-
ANNUAL REPORT 2021
