This study measured the structural and organizational changesin the knowledge schema of human cognition in response to the learning achieved by 48 students enrolled in the second year of a psychologydegree. Two studies were carried out based on the Chronometric Constructive Cognitive Learning Evaluation Model. This article deals only with the first one, which consisted of a conceptual definition task designed in line with the Natural Semantic Network technique. Participants defined ten target concepts with verbs, nouns, or adjectives (definers), and then weighed the grade of the semantic relationship between the definers and the target concepts. The data indicate that the initial knowledge structures had been modified towards the end of the course. The participants’ human cognition schema presented changes in terms of content, organization, and structure. This evidence supports the idea that the acquisition and transformation of the schemata learned in academic environments may be observed through cognitive s