Human Clinical Research Facility | 675 John Kimbrough Blvd. | Building #1542 College Station, TX 77845-4243 979/458-1498 | hcrf@tamu.edu | hcrf.tamu.edu
LEADERSHIP Richard B. Kreider, PhD, FACSM, FISSN, FACN, FNAK Professor, Department of Health & Kinesiology Director, Exercise & Sport Nutrition Lab Executive Director, Human Clinical Research Facility
Nicolaas E. Deutz, MD, PhD Professor, Department of Health & Kinesiology Director, Center for Translational Research in Aging & Longevity Director of Clinical Research, Human Clinical Research Facility
COLLABORATION OPTIONS Collaborative Grants PI’s and/or grant sponsors collaborate with HCRF researchers serving as Co-PI’s or Co-I’s on developing grant and contract proposals;
TEXAS A&M UNIVERSITY HUMAN CLINICAL RESEARCH FACILITY
obtaining IRB approval; conducting the clinical trials; data management and analysis;
The Human Clinical Research Facility (HCRF), a 23,000 square foot biomedical research facility
presenting results; and, publishing research
that was developed to provide a centralized research facility for clinical researchers to conduct
findings. IDC's are shared among Co-PI's.
human clinical research trials at Texas A&M University. The HCRF houses two primary research groups from the Department of Health & Kinesiology in the College of Education and Human Development; the Exercise and Sport Nutrition Laboratory (ESNL) and the Center for Translational Research in Aging and Longevity (CTRAL). The ESNL was developed in 1997 under the direction of Richard B. Kreider, PhD and is dedicated to study the role of exercise and nutrition on health, disease, rehabilitation and performance. The CTRAL was developed in 2006 under the direction of Nicolaas E. Deutz, MD, PhD and Marielle P. Engelen, PhD and is dedicated to the study of translational research on nutrition, exercise, and metabolism in relation to aging and the common diseases of our aging population.
Fee for Service Testing TAMU PI’s and/or external sponsors work with the HCRF directors and staff to coordinate collection of data on IRB approved independently designed, funded, and managed clinical trials on a fee for service basis.
FACILITY OVERVIEW
CLINICAL TESTING & REHABILATATION The Human Clinical Research Facility provides approximately 23,000-square-feet of new space, and includes the following: Level 1: 9,863 sq. ft. • Circuit & Group Training •
Exercise Training & Rehabilitation
•
Break Room
•
Faculty Offices
•
Graduate Assistants
•
Conference Room
•
Work Room
Level 2: 12,189 sq. ft. • Study Rooms •
Metabolic & Fluxomics Unit Laboratory BioBank
•
Metabolic Kitchen
•
Clinical Preparation
•
Nurse Station
•
Clinical Testing Exam Rooms - Dexa Room - REE Room -
CONCEPT DESIGN
Project Initiation / Review IRB Submission Assistance Participant Recruitment, Familiarization, Scheduling and Enrollment Use large database of previously recruited subjects with diseases like COPD, CHF, Cancer, ASD, MCI and healthy subjects Entrance Criteria Exam by Medical Screening Phlebotomy, Biopsy, Sample Handling, and Storage IV Solution Infusions Clinical Chemistry Analysis LC-MS/MS and GC-MS/MS Analysis Biobank with 15 year of samples of human studies that received stable isotope solutions Muscle and Fat Biopsies 24 hour Nursing Supervision
*
RESEARCH SERVICES
LANDSCAPE
Level 1 Floor Plan
Level 2 Floor Plan
FLOOR PLANS
ARCHITECTURE
PBKSPORTS.com
INTERIORS
INTERIORS
ARCHITECTURE
PBKSPORTS.com
FLOOR PLANS
LANDSCAPE
Level 1 Floor Plan
Level 2 Floor Plan
RESEARCH SERVICES
CONCEPT DESIGN
Project Initiation / Review IRB Submission Assistance Participant Recruitment, Familiarization, Scheduling and Enrollment Use large database of previously recruited subjects with diseases like COPD, CHF, Cancer, ASD, MCI and healthy subjects Entrance Criteria Exam by Medical Screening Phlebotomy, Biopsy, Sample Handling, and Storage IV Solution Infusions Clinical Chemistry Analysis LC-MS/MS and GC-MS/MS Analysis Biobank with 15 year of samples of human studies that received stable isotope solutions Muscle and Fat Biopsies 24 hour Nursing Supervision
*
RESEARCH CAPABILITIES Exercise Training & Rehabilitation Physiological Testing
Preliminary Concepts
Height / Weight Skinfold Body Composition Bioelectrical Impedance (BIA) Body Composition/Bone Density Assessment (DEXA) Dietary intake analysis (4-day) Lung function Resting Energy Expenditure ECG Stress Test Cardiopulmonary / ECG Stress Test Endurance Time to Exhaustion Test Isotonic Strength Testing Isokinetic Strength Testing Anaerobic Capacity Testing Balance/Gait Analysis Biomechanical Analyses Cognitive Function Psychosocial Assessment Clinical Research Unit for Overnight Stay Research Bedrest Studies Sleep Studies Comprehensive Wet Lab Facility for Sample Analysis Stable Isotope Tracer Metabolism Studies Anabolic Response to Food Digestion and Absorption of Nutrients Protein Synthesis/Breakdown Tissue (muscle, fat) Protein and Fatty Synthesis Metabolic Kinetic Phenotyping Using a 20 Stable Tracer Mixture Intravenous Pulse Elevation Study
Data Entry / Management Data Storage Clinical Trial Consulting
11 GREENWAY PLAZA, 22ND FLOOR, HOUSTON, TX 77046 \\ 1-800-838-7272
VISION/MASTER PLANNING
CLINICAL TESTING & REHABILATATION The Human Clinical Research Facility provides approximately 23,000-square-feet of new space, and includes the following: Level 1: 9,863 sq. ft. • Circuit & Group Training •
Exercise Training & Rehabilitation
•
Break Room
•
Faculty Offices
•
Graduate Assistants
•
Conference Room
•
Work Room
Level 2: 12,189 sq. ft. • Study Rooms •
Metabolic & Fluxomics Unit Laboratory BioBank
•
Metabolic Kitchen
•
Clinical Preparation
•
Nurse Station
•
Clinical Testing Exam Rooms - Dexa Room - REE Room -
FACILITY OVERVIEW
COLLABORATION OPTIONS Collaborative Grants PI’s and/or grant sponsors collaborate with HCRF researchers serving as Co-PI’s or Co-I’s on developing grant and contract proposals;
TEXAS A&M UNIVERSITY HUMAN CLINICAL RESEARCH FACILITY
obtaining IRB approval; conducting the clinical trials; data management and analysis;
The Human Clinical Research Facility (HCRF), a 23,000 square foot biomedical research facility
presenting results; and, publishing research
that was developed to provide a centralized research facility for clinical researchers to conduct
findings. IDC's are shared among Co-PI's.
human clinical research trials at Texas A&M University. The HCRF houses two primary research groups from the Department of Health & Kinesiology in the College of Education and Human Development; the Exercise and Sport Nutrition Laboratory (ESNL) and the Center for Translational Research in Aging and Longevity (CTRAL). The ESNL was developed in 1997 under the direction of Richard B. Kreider, PhD and is dedicated to study the role of exercise and nutrition on health, disease, rehabilitation and performance. The CTRAL was developed in 2006 under the direction of Nicolaas E. Deutz, MD, PhD and Marielle P. Engelen, PhD and is dedicated to the study of translational research on nutrition, exercise, and metabolism in relation to aging and the common diseases of our aging population.
Fee for Service Testing TAMU PI’s and/or external sponsors work with the HCRF directors and staff to coordinate collection of data on IRB approved independently designed, funded, and managed clinical trials on a fee for service basis.
LEADERSHIP Richard B. Kreider, PhD, FACSM, FISSN, FACN, FNAK Professor, Department of Health & Kinesiology Director, Exercise & Sport Nutrition Lab Executive Director, Human Clinical Research Facility
Nicolaas E. Deutz, MD, PhD Professor, Department of Health & Kinesiology Director, Center for Translational Research in Aging & Longevity Director of Clinical Research, Human Clinical Research Facility
Human Clinical Research Facility | 675 John Kimbrough Blvd. | Building #1542 College Station, TX 77845-4243 979/458-1498 | hcrf@tamu.edu | hcrf.tamu.edu