Decontamination of mycotoxins in experimental models Mycotoxins in feed necessitated the
Dietary supplementation of rutin in
development of novel technologies that
Nile tilapia improves growth, elevated
would be useful, environmentally friendly,
liver antioxidant capacity, and reduced
and cost-effective in their removal.
liver and myofiber damage induced by T-2-toxin (Deng et al., 2019).
Examples of some compounds used to ameliorate mycotoxin toxicity are described as follows.
Oxidative damage and hepatopancreas immune responses induced by T-2 toxin in Chinese mitten crab (Eriocheir sinensis) are reduced following dietary supplementation with arginine (Zhang et al., 2020).
Sodium selenite exhibits protective effects on AFB1-induced toxicity by inhibiting
Vitamina C supplementation
oxidative stress and excessive apoptosis
diminishes reproductive, immune,
in broilers’ spleen (Wang et al., 2013),
and hematological toxicity in piglets
decreasing DNA damage and histological
exposed to ZEN (Su et al., 2018).
alterations in ducklings’ liver (Shi et al.,
2015), and ameliorating reproductive toxicity in mice (Cao et al., 2017).
Resveratrol (RSV) is able to decrease or reverse ZEN-induced toxicity in adult male Wistar rats, enhancing antioxidant enzyme
Silymarin administration alleviates elevated Vascular endothelial growth factor (VEGF) and fibroblast growth factor-2 (FGF-2) expression levels and diminishes liver damage induced by FB1 in mice (Sozmen et al., 2014) .
activity and improving immune parameters
Lactobacillus paracasei alleviates genotoxicity, oxidative stress status, and histopathological damage induced by FB1 in mice (Ezdini et al., 2020),
(Longobardi et al., 2021).
while Lb. delbrueckii subsp. lactis (LL) and P. acidilactici (PA) strains induced a
in exposed rats (Virk et al., 2020). Curcumin modulates nitrosative stress, inflammation and DNA damage, hepatotoxicity, and nephrotoxicity induced by Ochratoxin A in Rats
Green tea-mediated zinc nanoparticles ameliorate the hepatotoxicity and nephrotoxicity induced by OTA in albino rats (Mansour et al., 2015).
protective effect against antigenotoxicity and precancerous lesions caused by FB1 in Sprague-Dawley Rats (Khalil et al., 2015) .
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