Dr. Steven R. Goldstein MD HRT Specialist – What are SERMs?
Dr. Steven R. Goldstein MD is the President of the International Menopause Society, a Certified Menopause Practitioner, and HRT Specialist in NYC. He has authored books on hormone replacement therapy for women and has used hormone therapy to successfully treat symptoms of menopause and perimenopause in women. A category of drugs known as SERMs (Selective Estrogen Receptor Modulators) can be used to help women cope with the many symptoms of menopause. What are SERM’s?
SERMs are first of all Selective, meaning they only act on certain areas or body parts. For instance, some of the SERMs will bind to the estrogen receptors in the bone and lipids, activating them. Another SERM will bind to, but not activate estrogen receptors in the breast and uterus. Essentially you get an estrogen effect where you need it, and block out such an effect where you don’t want it. The E stands for Estrogen, meaning they are the naturally occurring female hormone that is produced by the follicles that develop in a woman’s ovaries. Estrogen does many healthful things for a woman’s body that have nothing to do with reproduction. The level of estrogen in the body plummets after menopause. The R stands for Receptor meaning a specific site in the cells of the body that can be turned on or off by a drug or natural substance be it a SERM or Estrogen. It is estimated