THE HUB VISION Industrial biotechnology (IB) is entering a golden age of opportunity. Technological and scientific advances in biotechnology have revolutionised our ability to synthesise molecules of choice, giving access to novel chemistries that enable tuneable selectivity and the use of benign reaction conditions. These developments can now be coupled to advances in the industrialisation of biology to generate innovative manufacturing routes, supported by high throughput and real-time analytics, process automation, artificial intelligence and data-driven science. By harnessing the power of biology through innovative IB, the Future BRH is aiming to support the development of safer, cleaner and greener manufacturing supply chains, and processes that support the emergence of the bioeconomy that will place the UK at the forefront of global economic Clean Growth in key manufacturing sectors: • • • •
Pharmaceuticals; Value-added chemicals; Engineering materials; Advanced Biofuels
The strategy of the Future BRH is to address the entire manufacturing lifecycle, by considering aspects such as scale-up, process intensification, continuous manufacturing, and integrated and whole-process modelling. To achieve this the Hub is working to deliver new biocatalysts, robust industrial hosts and novel production technologies that will enable rapid transition from proof-of-concept to manufacturing at scale. The emphasis is on predictable deployment of sustainable and innovative biomanufacturing technologies through integrated technology development at all scales of production, harnessing UK-wide world-leading research expertise (particularly across the Hub and Spokes) and frontier science and technology, including data-driven Artificial Intelligence (AI) approaches, automation and new technologies emerging from the 'engineering of biology'.
FUTURE BIOMANUFACTURING RESEARCH HUB | futurebrh.com | Annual Report 2020
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